ARHGAP15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)6.11153711
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.94166024
3antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.94166024
4antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.69027005
5antigen processing and presentation of endogenous antigen (GO:0019883)5.45720089
6positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.01607660
7regulation of B cell receptor signaling pathway (GO:0050855)4.97730706
8regulation of gamma-delta T cell differentiation (GO:0045586)4.53832239
9negative T cell selection (GO:0043383)4.53483819
10negative thymic T cell selection (GO:0045060)4.45808788
11leukocyte aggregation (GO:0070486)4.41577410
12ribosomal small subunit assembly (GO:0000028)4.37627872
13positive regulation of B cell differentiation (GO:0045579)4.36414493
14mast cell activation (GO:0045576)4.33589295
15regulation of gamma-delta T cell activation (GO:0046643)4.25556228
16regulation of B cell differentiation (GO:0045577)4.11224542
17negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.08671191
18negative regulation of cell killing (GO:0031342)4.08671191
19Arp2/3 complex-mediated actin nucleation (GO:0034314)3.98471777
20interferon-gamma production (GO:0032609)3.97494327
21T cell migration (GO:0072678)3.95293642
22positive thymic T cell selection (GO:0045059)3.94704401
23response to interleukin-15 (GO:0070672)3.90121059
24B cell receptor signaling pathway (GO:0050853)3.84978447
25negative regulation of phagocytosis (GO:0050765)3.80275405
26cellular response to interleukin-15 (GO:0071350)3.76844157
27antigen processing and presentation via MHC class Ib (GO:0002475)3.69250184
28activated T cell proliferation (GO:0050798)3.69231499
29negative regulation of T cell mediated immunity (GO:0002710)3.63294717
30regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.62840714
31defense response to protozoan (GO:0042832)3.55766983
32positive T cell selection (GO:0043368)3.52768878
33regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.52023361
34regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.49434411
35response to protozoan (GO:0001562)3.44483560
36mast cell degranulation (GO:0043303)3.42628479
37mast cell activation involved in immune response (GO:0002279)3.42628479
38thymic T cell selection (GO:0045061)3.42383541
39regulation of isotype switching to IgG isotypes (GO:0048302)3.42148509
40regulation of T cell receptor signaling pathway (GO:0050856)3.40824748
41regulation of alpha-beta T cell proliferation (GO:0046640)3.40474654
42cellular response to interferon-beta (GO:0035458)3.39969148
43positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.39694501
44regulation of T cell tolerance induction (GO:0002664)3.35679342
45T cell selection (GO:0045058)3.35594318
46antigen receptor-mediated signaling pathway (GO:0050851)3.35585885
47negative regulation of lymphocyte mediated immunity (GO:0002707)3.34987345
48immunoglobulin mediated immune response (GO:0016064)3.33168681
49cytidine deamination (GO:0009972)3.32908932
50cytidine metabolic process (GO:0046087)3.32908932
51cytidine catabolic process (GO:0006216)3.32908932
52DNA deamination (GO:0045006)3.30930975
53T cell homeostasis (GO:0043029)3.29038868
54regulation of tolerance induction (GO:0002643)3.27745776
55cellular response to zinc ion (GO:0071294)3.27516045
56positive regulation of lamellipodium assembly (GO:0010592)3.24110997
57regulation of interleukin-12 biosynthetic process (GO:0045075)3.21656043
58T cell receptor signaling pathway (GO:0050852)3.18834304
59sequestering of actin monomers (GO:0042989)3.18284960
60response to interferon-beta (GO:0035456)3.17206486
61cellular extravasation (GO:0045123)3.16992656
62regulation of regulatory T cell differentiation (GO:0045589)3.11651560
63response to type I interferon (GO:0034340)3.09412695
64type I interferon signaling pathway (GO:0060337)3.08811684
65cellular response to type I interferon (GO:0071357)3.08811684
66positive regulation of alpha-beta T cell proliferation (GO:0046641)3.08354053
67negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.06767903
68myeloid dendritic cell activation (GO:0001773)3.05231820
69interferon-gamma-mediated signaling pathway (GO:0060333)3.04611477
70positive regulation of defense response to virus by host (GO:0002230)3.04008852
71pyrimidine ribonucleoside catabolic process (GO:0046133)3.03399878
72neutrophil activation (GO:0042119)3.02271109
73hepatocyte apoptotic process (GO:0097284)2.99912402
74positive regulation of isotype switching (GO:0045830)2.98543951
75positive regulation of granulocyte differentiation (GO:0030854)2.98462408
76negative regulation of B cell proliferation (GO:0030889)2.98033998
77mature B cell differentiation (GO:0002335)2.95965658
78megakaryocyte development (GO:0035855)2.95295970
79negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.95104618
80actin nucleation (GO:0045010)2.94388838
81definitive hemopoiesis (GO:0060216)2.94276433
82regulation of leukocyte mediated cytotoxicity (GO:0001910)2.93714597
83neutrophil activation involved in immune response (GO:0002283)2.91567412
84positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.91499259
85T cell costimulation (GO:0031295)2.91169200
86lymphocyte homeostasis (GO:0002260)2.91071894
87lymphocyte costimulation (GO:0031294)2.90157283
88regulation of granulocyte differentiation (GO:0030852)2.89867668
89Peyers patch development (GO:0048541)2.89644026
90mucosal-associated lymphoid tissue development (GO:0048537)2.89644026
91negative regulation of leukocyte mediated immunity (GO:0002704)2.89064633
92respiratory burst (GO:0045730)2.88765574
93positive regulation of mast cell activation (GO:0033005)2.88253448
94negative regulation of interleukin-12 production (GO:0032695)2.86970849
95positive regulation of tolerance induction (GO:0002645)2.84551347
96regulation of natural killer cell mediated immunity (GO:0002715)2.84414965
97regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.84414965
98negative regulation of adaptive immune response (GO:0002820)2.84260988
99regulation of response to interferon-gamma (GO:0060330)2.83733156
100positive regulation of T cell differentiation in thymus (GO:0033089)2.83072344
101regulation of mast cell activation (GO:0033003)2.83005780
102B cell mediated immunity (GO:0019724)2.82365703
103microglial cell activation (GO:0001774)2.79392883
104tolerance induction (GO:0002507)2.79353175
105regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.77929505
106positive regulation of interleukin-2 production (GO:0032743)2.77002650
107leukocyte cell-cell adhesion (GO:0007159)2.76800477
108positive regulation of DNA recombination (GO:0045911)2.76217722
109modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.76091298
110modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.76091298
111positive regulation by organism of defense response of other organism involved in symbiotic interact2.76091298
112modulation by symbiont of host immune response (GO:0052553)2.76091298
113positive regulation by symbiont of host defense response (GO:0052509)2.76091298
114modulation by symbiont of host defense response (GO:0052031)2.76091298
115T cell proliferation (GO:0042098)2.74986710
116regulation of T cell mediated cytotoxicity (GO:0001914)2.74631012
117regulation of alpha-beta T cell activation (GO:0046634)2.74297065
118regulation of cell killing (GO:0031341)2.74003626
119NIK/NF-kappaB signaling (GO:0038061)2.73986673
120mature B cell differentiation involved in immune response (GO:0002313)2.73906782
121alpha-beta T cell differentiation (GO:0046632)2.73184062
122telomere maintenance via semi-conservative replication (GO:0032201)2.72568672
123regulation of T cell mediated immunity (GO:0002709)2.72499558
124leukocyte degranulation (GO:0043299)2.68335835
125leukocyte homeostasis (GO:0001776)2.68005974
126regulation of B cell mediated immunity (GO:0002712)2.66382616
127positive regulation of lamellipodium organization (GO:1902745)2.66311777
128regulation of isotype switching (GO:0045191)2.65517525
129angiogenesis involved in wound healing (GO:0060055)2.63051384
130myeloid cell activation involved in immune response (GO:0002275)2.62515166
131negative regulation of T cell receptor signaling pathway (GO:0050860)2.61912128
132positive regulation of macrophage differentiation (GO:0045651)2.61735903
133regulation of interleukin-2 biosynthetic process (GO:0045076)2.60352607
134viral transcription (GO:0019083)2.60080577
135positive regulation of immunoglobulin mediated immune response (GO:0002891)2.58729612
136positive regulation of B cell mediated immunity (GO:0002714)2.58729612
137positive regulation of T cell mediated cytotoxicity (GO:0001916)2.57559845
138regulation of necroptotic process (GO:0060544)2.57544827
139positive regulation of B cell activation (GO:0050871)2.56883914
140neutrophil mediated immunity (GO:0002446)2.56475717
141necroptotic process (GO:0070266)2.54752303

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.54750239
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.66497712
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.47744424
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.01175641
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.01032326
6* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.61339217
7IRF8_21731497_ChIP-ChIP_J774_Mouse3.31371059
8* SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.22313101
9SCL_19346495_ChIP-Seq_HPC-7_Human3.03216771
10* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.97891441
11IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.80577575
12STAT4_19710469_ChIP-ChIP_TH1__Mouse2.74711688
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.72618038
14* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.66484777
15* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.62264694
16STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.62081108
17* MYB_26560356_Chip-Seq_TH2_Human2.48952846
18BP1_19119308_ChIP-ChIP_Hs578T_Human2.48476277
19* FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.48344999
20MYC_22102868_ChIP-Seq_BL_Human2.45924476
21SPI1_23547873_ChIP-Seq_NB4_Human2.45790535
22* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.44204175
23RUNX_20019798_ChIP-Seq_JUKART_Human2.40797605
24* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.37488115
25* IRF8_27001747_Chip-Seq_BMDM_Mouse2.30316410
26VDR_21846776_ChIP-Seq_THP-1_Human2.23046949
27FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.21834989
28NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.18918395
29MYB_26560356_Chip-Seq_TH1_Human2.15784376
30TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.12536759
31E2F4_17652178_ChIP-ChIP_JURKAT_Human2.09407054
32ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.06408288
33* MAF_26560356_Chip-Seq_TH1_Human2.06081132
34EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.04621447
35RUNX1_22412390_ChIP-Seq_EML_Mouse1.98961720
36SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.92426581
37NOTCH1_21737748_ChIP-Seq_TLL_Human1.91389162
38MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.89554828
39EGR1_19374776_ChIP-ChIP_THP-1_Human1.88353276
40* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.87916031
41UTX_26944678_Chip-Seq_JUKART_Human1.87263586
42SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.85779369
43FLI1_27457419_Chip-Seq_LIVER_Mouse1.85209862
44VDR_24763502_ChIP-Seq_THP-1_Human1.80419148
45NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.79981670
46ERG_20887958_ChIP-Seq_HPC-7_Mouse1.78576444
47SMAD_19615063_ChIP-ChIP_OVARY_Human1.77404144
48BRD4_27068464_Chip-Seq_AML-cells_Mouse1.71730199
49* VDR_23849224_ChIP-Seq_CD4+_Human1.70423192
50GATA1_22025678_ChIP-Seq_K562_Human1.67725231
51FOXM1_23109430_ChIP-Seq_U2OS_Human1.67111830
52* FOXP3_21729870_ChIP-Seq_TREG_Human1.62042056
53* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.61055230
54* LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.56970019
55VDR_22108803_ChIP-Seq_LS180_Human1.56639378
56CIITA_25753668_ChIP-Seq_RAJI_Human1.56118958
57VDR_24787735_ChIP-Seq_THP-1_Human1.56117726
58GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.52780259
59BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.52468621
60GATA2_22383799_ChIP-Seq_G1ME_Mouse1.51005176
61FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.50786978
62EST1_17652178_ChIP-ChIP_JURKAT_Human1.48645891
63SPI1_23127762_ChIP-Seq_K562_Human1.48215007
64* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.47601236
65FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.46759547
66* GATA3_27048872_Chip-Seq_THYMUS_Human1.46295415
67IGF1R_20145208_ChIP-Seq_DFB_Human1.45761564
68GABP_17652178_ChIP-ChIP_JURKAT_Human1.44233105
69PCGF2_27294783_Chip-Seq_ESCs_Mouse1.35496730
70MYC_18555785_ChIP-Seq_MESCs_Mouse1.34450338
71ELK1_19687146_ChIP-ChIP_HELA_Human1.33386703
72MAF_26560356_Chip-Seq_TH2_Human1.32794354
73* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.32674121
74TCF7_22412390_ChIP-Seq_EML_Mouse1.30477966
75GATA1_22383799_ChIP-Seq_G1ME_Mouse1.30428102
76PU_27001747_Chip-Seq_BMDM_Mouse1.29986211
77PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.27821372
78VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.21865024
79ZNF274_21170338_ChIP-Seq_K562_Hela1.21276146
80RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.18741310
81* GATA3_26560356_Chip-Seq_TH2_Human1.17811238
82VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.16316100
83* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.14854452
84SMRT_27268052_Chip-Seq_Bcells_Human1.13599637
85PCGF2_27294783_Chip-Seq_NPCs_Mouse1.12405902
86JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.11591464
87EGR1_23403033_ChIP-Seq_LIVER_Mouse1.10688142
88CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.08977907
89* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.08739012
90HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.08418224
91GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07866504
92ER_23166858_ChIP-Seq_MCF-7_Human1.07718047
93* GATA3_26560356_Chip-Seq_TH1_Human1.05828263
94MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.04612076
95KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.04566418
96POU3F2_20337985_ChIP-ChIP_501MEL_Human1.04330242
97MYC_18358816_ChIP-ChIP_MESCs_Mouse1.03454780
98ETS1_20019798_ChIP-Seq_JURKAT_Human1.03266209
99E2F1_21310950_ChIP-Seq_MCF-7_Human1.02703138
100IRF1_19129219_ChIP-ChIP_H3396_Human1.02397637
101PU.1_20513432_ChIP-Seq_Bcells_Mouse1.02383532
102NFE2_27457419_Chip-Seq_LIVER_Mouse1.01959463
103TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.01290258
104EZH2_27294783_Chip-Seq_NPCs_Mouse1.00851632
105SUZ12_27294783_Chip-Seq_NPCs_Mouse1.00673742
106CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.99933385
107SRF_21415370_ChIP-Seq_HL-1_Mouse0.99871660
108HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.98453789
109PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.97944132
110PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96236914
111* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96165733
112PRDM14_20953172_ChIP-Seq_ESCs_Human0.94371984
113MYC_19030024_ChIP-ChIP_MESCs_Mouse0.94133671
114GATA1_19941827_ChIP-Seq_MEL_Mouse0.93871343
115* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93241080
116CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.92951322
117PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.92550985
118* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92502226
119RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90620717
120STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.90443582
121CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90261285
122RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.89710596
123HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.89306192
124ETS1_22383799_ChIP-Seq_G1ME_Mouse0.88341734
125GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.88027680
126XRN2_22483619_ChIP-Seq_HELA_Human0.87963799
127KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.87658620
128PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86496151
129EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.85662950
130Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.85370298
131NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.84919003
132RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.83985256
133CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.83832694
134CRX_20693478_ChIP-Seq_RETINA_Mouse0.83713614
135FOXA1_21572438_ChIP-Seq_LNCaP_Human0.83535098
136EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.82544918
137PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.81980272
138TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.81206098
139GATA2_21666600_ChIP-Seq_HMVEC_Human0.79717861
140TP53_22573176_ChIP-Seq_HFKS_Human0.79535307
141OCT4_21477851_ChIP-Seq_ESCs_Mouse0.79370207
142SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.78251294

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.64528396
2MP0005671_abnormal_response_to3.83129225
3MP0003763_abnormal_thymus_physiology3.62316556
4MP0000685_abnormal_immune_system3.56211284
5MP0002396_abnormal_hematopoietic_system3.48007435
6MP0009785_altered_susceptibility_to3.21090199
7MP0001800_abnormal_humoral_immune3.09919282
8MP0005000_abnormal_immune_tolerance2.89825283
9MP0002420_abnormal_adaptive_immunity2.80846365
10MP0002452_abnormal_antigen_presenting2.77764478
11MP0001790_abnormal_immune_system2.77616163
12MP0005387_immune_system_phenotype2.77616163
13MP0001819_abnormal_immune_cell2.77192148
14MP0005025_abnormal_response_to2.75715013
15MP0002723_abnormal_immune_serum2.74247886
16MP0002166_altered_tumor_susceptibility2.73775651
17MP0003436_decreased_susceptibility_to2.72400448
18MP0002398_abnormal_bone_marrow2.68834315
19MP0002148_abnormal_hypersensitivity_rea2.58453843
20MP0002419_abnormal_innate_immunity2.53589944
21MP0000716_abnormal_immune_system2.37509387
22MP0003724_increased_susceptibility_to2.23982992
23MP0000689_abnormal_spleen_morphology2.23888779
24MP0002006_tumorigenesis2.21953296
25MP0005464_abnormal_platelet_physiology2.19637776
26MP0002722_abnormal_immune_system2.12614392
27MP0009333_abnormal_splenocyte_physiolog2.11247438
28MP0001853_heart_inflammation2.10115781
29MP0002405_respiratory_system_inflammati2.08948185
30MP0004808_abnormal_hematopoietic_stem2.07747692
31MP0002429_abnormal_blood_cell2.01256760
32MP0005174_abnormal_tail_pigmentation1.97113076
33MP0000703_abnormal_thymus_morphology1.96512045
34MP0010155_abnormal_intestine_physiology1.90620480
35MP0001873_stomach_inflammation1.82223190
36MP0003866_abnormal_defecation1.80273590
37MP0005397_hematopoietic_system_phenotyp1.76243104
38MP0001545_abnormal_hematopoietic_system1.76243104
39MP0005075_abnormal_melanosome_morpholog1.69361143
40MP0003303_peritoneal_inflammation1.68980914
41MP0001845_abnormal_inflammatory_respons1.67947225
42MP0006082_CNS_inflammation1.67562549
43MP0000465_gastrointestinal_hemorrhage1.64489647
44MP0010094_abnormal_chromosome_stability1.56209762
45MP0000490_abnormal_crypts_of1.46725761
46MP0004947_skin_inflammation1.46397438
47MP0008057_abnormal_DNA_replication1.44077822
48MP0000858_altered_metastatic_potential1.36467934
49MP0003300_gastrointestinal_ulcer1.35098460
50MP0008469_abnormal_protein_level1.34459766
51MP0002138_abnormal_hepatobiliary_system1.33271592
52MP0000015_abnormal_ear_pigmentation1.30141353
53MP0003693_abnormal_embryo_hatching1.21273977
54MP0002019_abnormal_tumor_incidence1.20416417
55MP0002933_joint_inflammation1.19234942
56MP0003077_abnormal_cell_cycle1.18140351
57MP0002095_abnormal_skin_pigmentation1.17986054
58MP0001533_abnormal_skeleton_physiology1.16006765
59MP0008007_abnormal_cellular_replicative1.11741776
60MP0000372_irregular_coat_pigmentation1.09554440
61MP0008058_abnormal_DNA_repair1.08959315
62MP0003183_abnormal_peptide_metabolism1.06228958
63MP0005058_abnormal_lysosome_morphology1.04251840
64MP0009278_abnormal_bone_marrow1.00666826
65MP0003787_abnormal_imprinting0.98255689
66MP0005310_abnormal_salivary_gland0.98040038
67MP0003172_abnormal_lysosome_physiology0.97876947
68MP0003045_fibrosis0.97304134
69MP0003111_abnormal_nucleus_morphology0.96847838
70MP0002009_preneoplasia0.96846419
71MP0003448_altered_tumor_morphology0.95697512
72MP0000343_altered_response_to0.95198259
73MP0000569_abnormal_digit_pigmentation0.92807724
74MP0009764_decreased_sensitivity_to0.91041256
75MP0003191_abnormal_cellular_cholesterol0.89467691
76MP0004381_abnormal_hair_follicle0.88199359
77MP0001986_abnormal_taste_sensitivity0.87691932
78MP0006054_spinal_hemorrhage0.87240308
79MP0004510_myositis0.85111808
80MP0002132_abnormal_respiratory_system0.84907807
81MP0009763_increased_sensitivity_to0.79383188
82MP0001851_eye_inflammation0.78740118
83MP0008872_abnormal_physiological_respon0.78640766
84MP0003195_calcinosis0.77698185
85MP0004957_abnormal_blastocyst_morpholog0.75646298
86MP0003252_abnormal_bile_duct0.74565541
87MP0002163_abnormal_gland_morphology0.74560651
88MP0003806_abnormal_nucleotide_metabolis0.72653601
89MP0008961_abnormal_basal_metabolism0.72482553
90MP0003646_muscle_fatigue0.71954431
91MP0001501_abnormal_sleep_pattern0.71615165
92MP0002876_abnormal_thyroid_physiology0.69685428
93MP0003656_abnormal_erythrocyte_physiolo0.69523799
94MP0004883_abnormal_blood_vessel0.69426078
95MP0002693_abnormal_pancreas_physiology0.68575935
96MP0010307_abnormal_tumor_latency0.68196340
97MP0002277_abnormal_respiratory_mucosa0.66673410
98MP0000313_abnormal_cell_death0.65353020
99MP0005645_abnormal_hypothalamus_physiol0.65334384
100MP0001919_abnormal_reproductive_system0.65320191
101MP0009765_abnormal_xenobiotic_induced0.65237969
102MP0003075_altered_response_to0.62878567
103MP0002998_abnormal_bone_remodeling0.62502530
104MP0004130_abnormal_muscle_cell0.62202996
105MP0003943_abnormal_hepatobiliary_system0.61872561
106MP0008873_increased_physiological_sensi0.60534420
107MP0010352_gastrointestinal_tract_polyps0.60121370
108MP0004484_altered_response_of0.59491423
109MP0001663_abnormal_digestive_system0.59380926
110MP0005166_decreased_susceptibility_to0.58837729
111MP0004147_increased_porphyrin_level0.56409398
112MP0003828_pulmonary_edema0.55575884
113MP0005167_abnormal_blood-brain_barrier0.55365668
114MP0001765_abnormal_ion_homeostasis0.54171471
115MP0008877_abnormal_DNA_methylation0.53221245
116MP0002136_abnormal_kidney_physiology0.51839819
117MP0000249_abnormal_blood_vessel0.50995752
118MP0005409_darkened_coat_color0.50034906
119MP0000371_diluted_coat_color0.45949376
120MP0000477_abnormal_intestine_morphology0.45445695
121MP0008874_decreased_physiological_sensi0.45203322
122MP0000604_amyloidosis0.44491678
123MP0003786_premature_aging0.43449212

Predicted human phenotypes

RankGene SetZ-score
1Elevated erythrocyte sedimentation rate (HP:0003565)5.68637042
2IgM deficiency (HP:0002850)4.96018962
3Recurrent abscess formation (HP:0002722)4.79024614
4Myositis (HP:0100614)4.43142033
5Chronic otitis media (HP:0000389)4.35924341
6Thrombocytosis (HP:0001894)4.29883534
7Recurrent bacterial skin infections (HP:0005406)4.20276871
8Recurrent bronchitis (HP:0002837)4.19224866
9Eczematoid dermatitis (HP:0000976)4.11444148
10Recurrent viral infections (HP:0004429)4.09268167
11Stomatitis (HP:0010280)4.07646292
12T lymphocytopenia (HP:0005403)4.02337129
13Recurrent fungal infections (HP:0002841)4.02061555
14Panhypogammaglobulinemia (HP:0003139)3.95840497
15IgG deficiency (HP:0004315)3.87825857
16Abnormality of T cells (HP:0002843)3.87603936
17Abnormality of T cell number (HP:0011839)3.83442981
18Meningitis (HP:0001287)3.66219162
19Abnormality of B cell number (HP:0010975)3.62491699
20B lymphocytopenia (HP:0010976)3.62491699
21Abnormality of T cell physiology (HP:0011840)3.55310416
22Agammaglobulinemia (HP:0004432)3.53937376
23Chronic mucocutaneous candidiasis (HP:0002728)3.48638049
24Recurrent cutaneous fungal infections (HP:0011370)3.48638049
25Abnormal delayed hypersensitivity skin test (HP:0002963)3.46584822
26Severe combined immunodeficiency (HP:0004430)3.43608539
27Thyroiditis (HP:0100646)3.31835179
28Mediastinal lymphadenopathy (HP:0100721)3.30873938
29Recurrent skin infections (HP:0001581)3.29994055
30Chronic obstructive pulmonary disease (HP:0006510)3.19253530
31Obstructive lung disease (HP:0006536)3.19253530
32Combined immunodeficiency (HP:0005387)3.16162109
33Retrobulbar optic neuritis (HP:0100654)3.12383339
34Optic neuritis (HP:0100653)3.12383339
35Petechiae (HP:0000967)3.10981302
36Abnormality of the prostate (HP:0008775)3.02626954
37Lymphopenia (HP:0001888)3.02009967
38Aplastic anemia (HP:0001915)3.01807836
39Abnormality of the fingertips (HP:0001211)3.01332301
40Vasculitis (HP:0002633)3.00983377
41Orchitis (HP:0100796)3.00368040
42Leukocytosis (HP:0001974)2.89721710
43Stomach cancer (HP:0012126)2.89004546
44Abnormality of cells of the lymphoid lineage (HP:0012140)2.87855044
45Cellulitis (HP:0100658)2.87817782
46Eosinophilia (HP:0001880)2.86723459
47Abnormality of eosinophils (HP:0001879)2.86486291
48Prolonged bleeding time (HP:0003010)2.85914456
49Lymphoma (HP:0002665)2.84277906
50Increased IgM level (HP:0003496)2.83836549
51Nasal polyposis (HP:0100582)2.82830754
52Inflammation of the large intestine (HP:0002037)2.80634240
53Encephalitis (HP:0002383)2.79023956
54Granulocytopenia (HP:0001913)2.73985380
55Gastrointestinal inflammation (HP:0004386)2.72214465
56Hypoplasia of the thymus (HP:0000778)2.70252493
57Recurrent sinusitis (HP:0011108)2.69987135
58Hypergammaglobulinemia (HP:0010702)2.64961340
59IgA deficiency (HP:0002720)2.64230509
60Chronic diarrhea (HP:0002028)2.64051736
61Gangrene (HP:0100758)2.63487592
62Abnormality of macrophages (HP:0004311)2.59888036
63Epistaxis (HP:0000421)2.56805250
64Recurrent gram-negative bacterial infections (HP:0005420)2.52461163
65Chest pain (HP:0100749)2.51680944
66Pulmonary embolism (HP:0002204)2.51346185
67Spontaneous hematomas (HP:0007420)2.47798276
68Pulmonary infiltrates (HP:0002113)2.46640406
69Abnormality of the pleura (HP:0002103)2.45310532
70Abnormal number of erythroid precursors (HP:0012131)2.44621663
71Hypoproteinemia (HP:0003075)2.43282497
72Keratoconjunctivitis sicca (HP:0001097)2.42893080
73Gastrointestinal stroma tumor (HP:0100723)2.42119640
74Abnormality of the nasal mucosa (HP:0000433)2.40767276
75Reticulocytopenia (HP:0001896)2.39913562
76Hemoptysis (HP:0002105)2.39857775
77Gingivitis (HP:0000230)2.39586967
78Pustule (HP:0200039)2.38159566
79Abnormality of cells of the erythroid lineage (HP:0012130)2.36569741
80Periodontitis (HP:0000704)2.35724308
81Vacuolated lymphocytes (HP:0001922)2.32837692
82Anorexia (HP:0002039)2.32594815
83Gastrointestinal infarctions (HP:0005244)2.31845568
84Bronchitis (HP:0012387)2.31672107
85Colitis (HP:0002583)2.30891651
86Autoimmune thrombocytopenia (HP:0001973)2.28485472
87Joint swelling (HP:0001386)2.27504963
88Chronic sinusitis (HP:0011109)2.26278836
89Arterial thrombosis (HP:0004420)2.23553343
90Increased neuronal autofluorescent lipopigment (HP:0002074)2.21859085
91Prostate neoplasm (HP:0100787)2.21205702
92Autoimmune hemolytic anemia (HP:0001890)2.19468350
93Recurrent pneumonia (HP:0006532)2.19063280
94Keratoconjunctivitis (HP:0001096)2.18373580
95Neutropenia (HP:0001875)2.18298454
96Increased IgE level (HP:0003212)2.18277087
97Amaurosis fugax (HP:0100576)2.16864309
98Alveolar cell carcinoma (HP:0006519)2.15037345
99Osteomyelitis (HP:0002754)2.14956267
100Gingival bleeding (HP:0000225)2.11745939
101Polyneuropathy (HP:0001271)2.10587079
102Absent rod-and cone-mediated responses on ERG (HP:0007688)2.09382701
103Poikiloderma (HP:0001029)2.08090350
104Sepsis (HP:0100806)2.07353788
105Urticaria (HP:0001025)2.06449611
106Keratitis (HP:0000491)2.05682966
107Recurrent lower respiratory tract infections (HP:0002783)2.05587595
108Myelodysplasia (HP:0002863)2.05075461
109Neoplasm of the tracheobronchial system (HP:0100552)2.03040153
110Congenital stationary night blindness (HP:0007642)2.02044300
111Vertigo (HP:0002321)1.99281615
112Skin rash (HP:0000988)1.97273831
113Abnormality of male internal genitalia (HP:0000022)1.96986239
114Impaired platelet aggregation (HP:0003540)1.96882382
115Abnormal platelet function (HP:0011869)1.96882382
116Papilloma (HP:0012740)1.96452495
117Verrucae (HP:0200043)1.96452495
118Hypochromic anemia (HP:0001931)1.95820087
119Pulmonary fibrosis (HP:0002206)1.95577580
120Glomerulopathy (HP:0100820)1.95171391
121Attenuation of retinal blood vessels (HP:0007843)1.94796029
122Acute hepatic failure (HP:0006554)1.94579367
123Thrombophlebitis (HP:0004418)1.90180470
124Increased cerebral lipofuscin (HP:0011813)1.85849653
125Decreased electroretinogram (ERG) amplitude (HP:0000654)1.81061016

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.89204327
2TXK4.30356340
3FRK3.17733683
4KIT2.94536189
5MAP3K122.80175958
6TEC2.68008108
7ZAP702.61808673
8IRAK42.46583498
9BTK2.41405989
10TYK22.27396021
11JAK32.26836236
12IKBKE2.19173574
13ITK2.08003590
14BLK2.07368740
15BMPR22.05339201
16SYK1.94298593
17PIK3CG1.93325462
18MAP3K141.91777848
19FLT31.80688921
20STK101.76100878
21GRK61.72703355
22CSF1R1.69645949
23TBK11.67214912
24TAOK31.67018526
25LCK1.62468301
26RIPK41.53920625
27ZAK1.43221182
28CLK11.41824543
29NUAK11.41112761
30JAK11.39329771
31MAP3K131.39006632
32TNK21.37692624
33IKBKB1.37063575
34MAP2K31.34536417
35NME21.30801911
36LYN1.29979327
37HCK1.29503829
38FES1.28992396
39PIM11.25924958
40VRK11.21361474
41MAP4K21.19035889
42MKNK11.17127258
43PIM21.12991453
44TESK21.11958596
45STK161.11331848
46EEF2K1.10276691
47IRAK31.07218601
48KDR1.05037200
49IRAK11.01573567
50BCKDK0.95592909
51NLK0.94670936
52CSK0.93545853
53MAPKAPK50.93229743
54FGFR40.91157119
55DAPK10.87609033
56GRK70.85164222
57LRRK20.84755995
58EIF2AK30.83738251
59CDC70.81579043
60MST40.81198724
61ACVR1B0.80586061
62FGFR30.77483024
63TGFBR20.73946014
64TGFBR10.72876408
65STK40.71593301
66WEE10.71401737
67ADRBK20.70795630
68CHUK0.70312251
69PRKCQ0.68449393
70MUSK0.67109043
71PINK10.66392797
72MAP2K20.65069702
73ATR0.64998331
74MATK0.63463079
75MAPK40.63339133
76TLK10.63027382
77GRK10.62725699
78OXSR10.62295806
79JAK20.62214491
80BMPR1B0.61254247
81EPHA30.61046055
82MYLK0.60233605
83PDK10.59653521
84CAMKK20.58238212
85CCNB10.57746019
86BUB10.57387674
87CDK80.57111616
88ERN10.56098750
89BRSK20.55489969
90CDK40.54638741
91TNIK0.53850533
92MAP3K100.53795849
93RPS6KA60.53286057
94CDK190.52367919
95SIK30.50862973
96SRPK10.50655937
97MARK30.49972755
98EIF2AK10.49325093
99RPS6KB20.48281176
100DAPK20.47867315
101TRPM70.47408044
102MAP3K110.47383595
103MAP3K60.46975177
104PTK2B0.46902839
105GRK50.46881061
106ADRBK10.46231499
107RPS6KA40.45886155
108IGF1R0.45167522
109MAPK130.44800137
110SIK20.43626730
111RPS6KA50.43515830
112ABL10.42527932
113MAP3K10.42217415
114FYN0.41678339
115CAMKK10.40906078
116MAP2K60.39556954
117HIPK20.39275330
118RPS6KC10.39268074
119RPS6KL10.39268074
120FGR0.39240209
121BRD40.37943289
122MAPK110.37348707
123NEK20.37244041
124PASK0.36606619
125PRKCD0.35656189
126PKN20.35619323
127CDK60.35431880
128MAPK70.35373830
129PRKCH0.33116449
130MAP3K50.32480195
131PIK3CA0.30456904
132STK110.30160990
133TRIM280.30113075
134SCYL20.28968804
135INSRR0.28310951
136EGFR0.27680624
137MAPK30.27005353
138EPHB10.23821792
139MAP3K30.23593149

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.55324950
2DNA replication_Homo sapiens_hsa030302.90346557
3Intestinal immune network for IgA production_Homo sapiens_hsa046722.66658084
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.42791327
5Allograft rejection_Homo sapiens_hsa053302.35261991
6Leishmaniasis_Homo sapiens_hsa051402.33632081
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.30456780
8Measles_Homo sapiens_hsa051622.29325917
9Antigen processing and presentation_Homo sapiens_hsa046122.28162115
10T cell receptor signaling pathway_Homo sapiens_hsa046602.20000436
11B cell receptor signaling pathway_Homo sapiens_hsa046622.18495634
12Mismatch repair_Homo sapiens_hsa034302.17304211
13Ribosome_Homo sapiens_hsa030102.16486019
14Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.13610928
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.12664659
16Hematopoietic cell lineage_Homo sapiens_hsa046402.05643188
17Base excision repair_Homo sapiens_hsa034102.04928075
18RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.79000723
19Homologous recombination_Homo sapiens_hsa034401.77847869
20Osteoclast differentiation_Homo sapiens_hsa043801.76509578
21Herpes simplex infection_Homo sapiens_hsa051681.74280952
22Graft-versus-host disease_Homo sapiens_hsa053321.71655818
23Non-homologous end-joining_Homo sapiens_hsa034501.62474918
24Asthma_Homo sapiens_hsa053101.55504365
25NOD-like receptor signaling pathway_Homo sapiens_hsa046211.53465143
26Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.43963858
27Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.42560505
28Jak-STAT signaling pathway_Homo sapiens_hsa046301.41621710
29Nucleotide excision repair_Homo sapiens_hsa034201.37520430
30Toll-like receptor signaling pathway_Homo sapiens_hsa046201.35210029
31Shigellosis_Homo sapiens_hsa051311.34227035
32Spliceosome_Homo sapiens_hsa030401.30484659
33Autoimmune thyroid disease_Homo sapiens_hsa053201.29331245
34Viral myocarditis_Homo sapiens_hsa054161.26273314
35Legionellosis_Homo sapiens_hsa051341.25604456
36Pertussis_Homo sapiens_hsa051331.24499668
37Other glycan degradation_Homo sapiens_hsa005111.21400187
38Influenza A_Homo sapiens_hsa051641.18913442
39Hepatitis B_Homo sapiens_hsa051611.15516587
40Toxoplasmosis_Homo sapiens_hsa051451.12518658
41Tuberculosis_Homo sapiens_hsa051521.10894479
42Acute myeloid leukemia_Homo sapiens_hsa052211.10476441
43Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.10323469
44Chemokine signaling pathway_Homo sapiens_hsa040621.09645049
45Platelet activation_Homo sapiens_hsa046111.03980631
46alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.02930491
47RNA degradation_Homo sapiens_hsa030181.02610417
48Malaria_Homo sapiens_hsa051441.02407989
49Transcriptional misregulation in cancer_Homo sapiens_hsa052021.01322750
50Fanconi anemia pathway_Homo sapiens_hsa034600.99903391
51Leukocyte transendothelial migration_Homo sapiens_hsa046700.98376833
52Apoptosis_Homo sapiens_hsa042100.97550395
53Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.96708560
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.92868608
55Salmonella infection_Homo sapiens_hsa051320.91941309
56Phototransduction_Homo sapiens_hsa047440.90862161
57Pyrimidine metabolism_Homo sapiens_hsa002400.90412076
58Epstein-Barr virus infection_Homo sapiens_hsa051690.88964201
59Linoleic acid metabolism_Homo sapiens_hsa005910.85865322
60Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.85216610
61Cell cycle_Homo sapiens_hsa041100.84241019
62Proteasome_Homo sapiens_hsa030500.81958876
63TNF signaling pathway_Homo sapiens_hsa046680.78432183
64Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.77701681
65Type I diabetes mellitus_Homo sapiens_hsa049400.75324518
66Viral carcinogenesis_Homo sapiens_hsa052030.74609443
67Systemic lupus erythematosus_Homo sapiens_hsa053220.74360283
68Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.74328634
69Staphylococcus aureus infection_Homo sapiens_hsa051500.73130054
70RNA polymerase_Homo sapiens_hsa030200.71490439
71Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.71031773
72p53 signaling pathway_Homo sapiens_hsa041150.68179828
73HTLV-I infection_Homo sapiens_hsa051660.67113167
74Hepatitis C_Homo sapiens_hsa051600.64784338
75Pancreatic cancer_Homo sapiens_hsa052120.64742559
76Arachidonic acid metabolism_Homo sapiens_hsa005900.62613392
77Dorso-ventral axis formation_Homo sapiens_hsa043200.62365896
78Protein export_Homo sapiens_hsa030600.61890743
79Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.61084374
80Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.60733496
81Chronic myeloid leukemia_Homo sapiens_hsa052200.60537674
82Regulation of autophagy_Homo sapiens_hsa041400.60069607
83Pentose phosphate pathway_Homo sapiens_hsa000300.59547674
84Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.58703518
85Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.57137540
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57096489
87Basal transcription factors_Homo sapiens_hsa030220.56604636
88Non-small cell lung cancer_Homo sapiens_hsa052230.54834183
89Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54721764
90N-Glycan biosynthesis_Homo sapiens_hsa005100.54409262
91Nitrogen metabolism_Homo sapiens_hsa009100.54151795
92Rheumatoid arthritis_Homo sapiens_hsa053230.52110915
93Olfactory transduction_Homo sapiens_hsa047400.51682556
94African trypanosomiasis_Homo sapiens_hsa051430.51449374
95Ether lipid metabolism_Homo sapiens_hsa005650.49424081
96RNA transport_Homo sapiens_hsa030130.49370981
97Neurotrophin signaling pathway_Homo sapiens_hsa047220.49353849
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47796122
99Caffeine metabolism_Homo sapiens_hsa002320.47056937
100Glycosaminoglycan degradation_Homo sapiens_hsa005310.44511635
101Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.42867839
102Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.42574078
103VEGF signaling pathway_Homo sapiens_hsa043700.41705932
104Purine metabolism_Homo sapiens_hsa002300.40706685
105Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40496458
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.39153657
107ABC transporters_Homo sapiens_hsa020100.38793910
108AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.37489098
109Prolactin signaling pathway_Homo sapiens_hsa049170.36354728
110Colorectal cancer_Homo sapiens_hsa052100.35086188
111Glycerophospholipid metabolism_Homo sapiens_hsa005640.34926849
112Thyroid cancer_Homo sapiens_hsa052160.34551276
113Phosphatidylinositol signaling system_Homo sapiens_hsa040700.34014421
114Peroxisome_Homo sapiens_hsa041460.31554616
115Lysosome_Homo sapiens_hsa041420.31059083
116Carbohydrate digestion and absorption_Homo sapiens_hsa049730.30837234
117Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.29509766
118Phagosome_Homo sapiens_hsa041450.27721696
119Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.27688840
120Small cell lung cancer_Homo sapiens_hsa052220.27686243
121Salivary secretion_Homo sapiens_hsa049700.20652287
122FoxO signaling pathway_Homo sapiens_hsa040680.17609016
123MAPK signaling pathway_Homo sapiens_hsa040100.17500335
124Tryptophan metabolism_Homo sapiens_hsa003800.16305717
125Morphine addiction_Homo sapiens_hsa050320.13723240
126Renin secretion_Homo sapiens_hsa049240.13578051
127Inositol phosphate metabolism_Homo sapiens_hsa005620.13284586
128Steroid hormone biosynthesis_Homo sapiens_hsa001400.12460686
129Vascular smooth muscle contraction_Homo sapiens_hsa042700.11551217

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