ARHGAP20

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is an activator of RHO-type GTPases, transducing a signal from RAP1 to RHO and impacting neurite outgrowth. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.69171023
2regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.23378414
3vocalization behavior (GO:0071625)5.22316519
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.18555812
5locomotory exploration behavior (GO:0035641)5.11712768
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.03138628
7synaptic vesicle maturation (GO:0016188)4.85800646
8neuron cell-cell adhesion (GO:0007158)4.83204310
9protein localization to synapse (GO:0035418)4.81190083
10regulation of glutamate receptor signaling pathway (GO:1900449)4.74815078
11synaptic vesicle exocytosis (GO:0016079)4.69934778
12synaptic vesicle docking involved in exocytosis (GO:0016081)4.68105518
13ionotropic glutamate receptor signaling pathway (GO:0035235)4.68093287
14glutamate secretion (GO:0014047)4.57110266
15regulation of synaptic vesicle exocytosis (GO:2000300)4.47451033
16synaptic transmission, glutamatergic (GO:0035249)4.35653756
17glutamate receptor signaling pathway (GO:0007215)4.34605787
18exploration behavior (GO:0035640)4.31128006
19regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.19531289
20neurotransmitter-gated ion channel clustering (GO:0072578)4.11285013
21neuron-neuron synaptic transmission (GO:0007270)4.06847801
22regulation of synaptic vesicle transport (GO:1902803)4.03043545
23regulation of synapse structural plasticity (GO:0051823)3.97253125
24layer formation in cerebral cortex (GO:0021819)3.92743297
25regulation of long-term neuronal synaptic plasticity (GO:0048169)3.91161298
26positive regulation of synapse maturation (GO:0090129)3.84472562
27regulation of neuronal synaptic plasticity (GO:0048168)3.84126195
28low-density lipoprotein particle clearance (GO:0034383)3.83808549
29neuronal action potential propagation (GO:0019227)3.79674274
30neuron recognition (GO:0008038)3.74750170
31neurotransmitter secretion (GO:0007269)3.73384428
32postsynaptic membrane organization (GO:0001941)3.69000296
33cilium or flagellum-dependent cell motility (GO:0001539)3.68325932
34presynaptic membrane assembly (GO:0097105)3.66240942
35regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.65904704
36regulation of cAMP-dependent protein kinase activity (GO:2000479)3.64403972
37regulation of excitatory postsynaptic membrane potential (GO:0060079)3.62931241
38dendritic spine morphogenesis (GO:0060997)3.60945920
39gamma-aminobutyric acid transport (GO:0015812)3.59518639
40membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.59399492
41G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.54451122
42axonal fasciculation (GO:0007413)3.51823490
43regulation of postsynaptic membrane potential (GO:0060078)3.51815873
44long-term memory (GO:0007616)3.51392087
45gamma-aminobutyric acid signaling pathway (GO:0007214)3.48566056
46regulation of dendritic spine morphogenesis (GO:0061001)3.45199756
47regulation of synaptic transmission, glutamatergic (GO:0051966)3.43459804
48membrane depolarization during action potential (GO:0086010)3.37684537
49calcium ion-dependent exocytosis (GO:0017156)3.37670929
50positive regulation of membrane potential (GO:0045838)3.37135900
51proline transport (GO:0015824)3.36977198
52presynaptic membrane organization (GO:0097090)3.36617752
53positive regulation of neurotransmitter secretion (GO:0001956)3.31968649
54sodium ion export (GO:0071436)3.31029268
55positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.31006512
56transmission of nerve impulse (GO:0019226)3.29701084
57regulation of sequestering of triglyceride (GO:0010889)3.27450402
58regulation of synaptic plasticity (GO:0048167)3.25035960
59behavioral defense response (GO:0002209)3.24190885
60behavioral fear response (GO:0001662)3.24190885
61response to histamine (GO:0034776)3.21513756
62positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.18224992
63cerebellar Purkinje cell differentiation (GO:0021702)3.17817865
64dendrite morphogenesis (GO:0048813)3.17260175
65negative regulation of synaptic transmission, GABAergic (GO:0032229)3.17199024
66regulation of neurotransmitter secretion (GO:0046928)3.16859861
67central nervous system projection neuron axonogenesis (GO:0021952)3.16695677
68cerebellar granule cell differentiation (GO:0021707)3.16114788
69auditory behavior (GO:0031223)3.15572066
70long-term synaptic potentiation (GO:0060291)3.14030197
71cellular potassium ion homeostasis (GO:0030007)3.12922266
72positive regulation of cardiac muscle hypertrophy (GO:0010613)3.12569090
73positive regulation of muscle hypertrophy (GO:0014742)3.12569090
74activation of protein kinase A activity (GO:0034199)3.10891746
75membrane depolarization (GO:0051899)3.10316880
76positive regulation of synaptic transmission, GABAergic (GO:0032230)3.10230652
77cell wall macromolecule metabolic process (GO:0044036)3.05800763
78cell wall macromolecule catabolic process (GO:0016998)3.05800763
79synaptic vesicle endocytosis (GO:0048488)3.05177153
80regulation of synapse maturation (GO:0090128)3.04047589
81fear response (GO:0042596)3.03643315
82positive regulation of phosphoprotein phosphatase activity (GO:0032516)3.02932391
83positive regulation of neurotransmitter transport (GO:0051590)3.00602074
84neurotransmitter transport (GO:0006836)3.00343048
85regulation of dendritic spine development (GO:0060998)2.98977457
86membrane hyperpolarization (GO:0060081)2.97149155
87regulation of vesicle fusion (GO:0031338)2.96879952
88neuromuscular process controlling balance (GO:0050885)2.95108382
89peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.94192345
90innervation (GO:0060384)2.93280056
91negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.92247003
92short-term memory (GO:0007614)2.91989164
93learning (GO:0007612)2.91428075
94synapse assembly (GO:0007416)2.91353781
95vesicle transport along microtubule (GO:0047496)2.90938883
96triglyceride catabolic process (GO:0019433)2.89887631
97regulation of neurotransmitter transport (GO:0051588)2.89033630
98startle response (GO:0001964)2.88759662
99fusion of sperm to egg plasma membrane (GO:0007342)2.88422511
100plasma membrane fusion (GO:0045026)2.88377803
101regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.87976464
102cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.87654592
103cochlea development (GO:0090102)2.86578170
104cerebellar Purkinje cell layer development (GO:0021680)2.84456522
105prepulse inhibition (GO:0060134)2.83812735
106response to auditory stimulus (GO:0010996)2.83399146
107mechanosensory behavior (GO:0007638)2.82577113
108neuronal ion channel clustering (GO:0045161)2.81243518
109cellular response to epinephrine stimulus (GO:0071872)2.80226126
110synaptic transmission (GO:0007268)2.79228947
111L-amino acid import (GO:0043092)2.79137886
112regulation of neurotransmitter levels (GO:0001505)2.78530861
113detection of calcium ion (GO:0005513)2.78400913
114neutral lipid catabolic process (GO:0046461)2.77482096
115acylglycerol catabolic process (GO:0046464)2.77482096
116cGMP-mediated signaling (GO:0019934)2.75357940
117intraspecies interaction between organisms (GO:0051703)2.74768400
118parturition (GO:0007567)2.69437548
119regulation of cholesterol storage (GO:0010885)2.66226174
120cellular sodium ion homeostasis (GO:0006883)2.62245061
121regulation of axon extension involved in axon guidance (GO:0048841)2.62072545
122regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.61764770
123negative regulation of dendrite development (GO:2000171)2.61276080
124regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.58178966
125positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.53955367
126negative regulation of dendrite morphogenesis (GO:0050774)2.51449091
127regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.50392000
128positive regulation of dendritic spine development (GO:0060999)2.49167697
129regulation of axon guidance (GO:1902667)2.46887144
130regulation of cardiac muscle hypertrophy (GO:0010611)2.45642404
131cell communication by electrical coupling (GO:0010644)2.43945794
132response to epinephrine (GO:0071871)2.43057311
133negative regulation of fatty acid transport (GO:2000192)2.42467157
134membrane assembly (GO:0071709)2.41692000
135fatty acid homeostasis (GO:0055089)2.41367805
136amino acid import (GO:0043090)2.40947031
137response to dietary excess (GO:0002021)2.37520507
138regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.35707893
139regulation of muscle hypertrophy (GO:0014743)2.34516460
140triglyceride biosynthetic process (GO:0019432)2.33243873
141protein localization to cell surface (GO:0034394)2.31209095
142protein heterotrimerization (GO:0070208)2.29861348
143cytoskeletal anchoring at plasma membrane (GO:0007016)2.24782258
144positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.23783063
145metanephric epithelium development (GO:0072207)2.23046624
146phagocytosis, recognition (GO:0006910)2.21858364
147cellular response to monoamine stimulus (GO:0071868)2.21590734
148cellular response to catecholamine stimulus (GO:0071870)2.21590734
149glucocorticoid biosynthetic process (GO:0006704)2.21162311

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.10282121
2GBX2_23144817_ChIP-Seq_PC3_Human3.70748624
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.68645178
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.59361470
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.55887226
6REST_21632747_ChIP-Seq_MESCs_Mouse2.43097875
7ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.32390818
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.25279594
9* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.23252516
10* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.23252516
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.19222857
12DROSHA_22980978_ChIP-Seq_HELA_Human2.18730203
13* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.16699590
14* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.15786930
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.14624060
16RARB_27405468_Chip-Seq_BRAIN_Mouse2.12007403
17BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.10344396
18* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.05089799
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.04951862
20CTBP2_25329375_ChIP-Seq_LNCAP_Human2.02016322
21* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.97506918
22RNF2_27304074_Chip-Seq_ESCs_Mouse1.97421849
23EZH2_27294783_Chip-Seq_ESCs_Mouse1.96004632
24ZFP57_27257070_Chip-Seq_ESCs_Mouse1.94096092
25GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.93249468
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.90982739
27TAF15_26573619_Chip-Seq_HEK293_Human1.89484784
28SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.88824457
29REST_18959480_ChIP-ChIP_MESCs_Mouse1.87711532
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.87142616
31* EED_16625203_ChIP-ChIP_MESCs_Mouse1.84486258
32* SMAD4_21799915_ChIP-Seq_A2780_Human1.79126987
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.71798197
34* AR_21572438_ChIP-Seq_LNCaP_Human1.71251202
35TRIM28_21343339_ChIP-Seq_HEK293_Human1.70951732
36TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.64719147
37PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.61938630
38EP300_21415370_ChIP-Seq_HL-1_Mouse1.60598115
39ZNF274_21170338_ChIP-Seq_K562_Hela1.60178125
40GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57852118
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.57056407
42NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.54599448
43IKZF1_21737484_ChIP-ChIP_HCT116_Human1.53834513
44NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.50335294
45NRF2_20460467_ChIP-Seq_MEFs_Mouse1.50335294
46P300_19829295_ChIP-Seq_ESCs_Human1.49473876
47PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.45880529
48SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.44726845
49POU3F2_20337985_ChIP-ChIP_501MEL_Human1.41097944
50SMAD3_21741376_ChIP-Seq_EPCs_Human1.39786555
51STAT3_23295773_ChIP-Seq_U87_Human1.39178879
52SOX2_21211035_ChIP-Seq_LN229_Gbm1.35614958
53AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.35389704
54CDX2_19796622_ChIP-Seq_MESCs_Mouse1.33630163
55* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32728004
56* CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.32695718
57PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.30922169
58* AR_25329375_ChIP-Seq_VCAP_Human1.30261581
59EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.30199341
60MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.27431396
61TCF4_23295773_ChIP-Seq_U87_Human1.26740654
62* FUS_26573619_Chip-Seq_HEK293_Human1.26506726
63SMAD_19615063_ChIP-ChIP_OVARY_Human1.26470493
64IGF1R_20145208_ChIP-Seq_DFB_Human1.26088053
65WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.23645221
66CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.21287860
67THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.20929758
68TP53_18474530_ChIP-ChIP_U2OS_Human1.20654398
69TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.20637113
70TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20049565
71POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.20049565
72* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19032793
73* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.18969824
74LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18614195
75UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17854351
76PIAS1_25552417_ChIP-Seq_VCAP_Human1.17691527
77* RNF2_27304074_Chip-Seq_NSC_Mouse1.17481993
78TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16959972
79OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16910091
80MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.16555048
81VDR_22108803_ChIP-Seq_LS180_Human1.16380740
82AR_19668381_ChIP-Seq_PC3_Human1.15120054
83CTNNB1_20460455_ChIP-Seq_HCT116_Human1.13028219
84RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.12928908
85EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.12348617
86NR3C1_23031785_ChIP-Seq_PC12_Mouse1.12201551
87CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.12129068
88TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.11893901
89NANOG_18555785_Chip-Seq_ESCs_Mouse1.11466761
90* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.11007642
91P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09964361
92ARNT_22903824_ChIP-Seq_MCF-7_Human1.09661389
93KDM2B_26808549_Chip-Seq_REH_Human1.08730243
94ZNF217_24962896_ChIP-Seq_MCF-7_Human1.08419476
95YAP1_20516196_ChIP-Seq_MESCs_Mouse1.07986579
96BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.07889019
97* RUNX2_22187159_ChIP-Seq_PCA_Human1.07019619
98RING1B_27294783_Chip-Seq_ESCs_Mouse1.06977670
99PRDM14_20953172_ChIP-Seq_ESCs_Human1.06542269
100BCAT_22108803_ChIP-Seq_LS180_Human1.05001417
101AHR_22903824_ChIP-Seq_MCF-7_Human1.04992983
102TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03788543
103TP53_16413492_ChIP-PET_HCT116_Human1.03345328
104ER_23166858_ChIP-Seq_MCF-7_Human1.02595980
105WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02405349
106CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01978928
107NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01568659
108FLI1_27457419_Chip-Seq_LIVER_Mouse1.01552290
109CLOCK_20551151_ChIP-Seq_293T_Human1.01518187
110RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.01451899
111* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.01410256
112KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.00583968
113ERG_21242973_ChIP-ChIP_JURKAT_Human0.99448733
114* PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.99392434
115FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.99012421
116EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98946825
117E2F1_18555785_Chip-Seq_ESCs_Mouse0.98946399
118SMAD3_21741376_ChIP-Seq_HESCs_Human0.97798613
119TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.95705529
120SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.94752105
121* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.92379343
122SMAD4_21741376_ChIP-Seq_HESCs_Human0.92217662
123RBPJ_22232070_ChIP-Seq_NCS_Mouse0.90914700
124CJUN_26792858_Chip-Seq_BT549_Human0.89844585

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.21885845
2MP0003880_abnormal_central_pattern4.86006257
3MP0003635_abnormal_synaptic_transmissio4.00061470
4MP0008438_abnormal_cutaneous_collagen3.71399635
5MP0004270_analgesia3.48339242
6MP0009745_abnormal_behavioral_response3.30604031
7MP0009046_muscle_twitch3.25186616
8MP0002063_abnormal_learning/memory/cond3.24817508
9MP0001968_abnormal_touch/_nociception3.11789116
10MP0002064_seizures2.90256572
11MP0002572_abnormal_emotion/affect_behav2.80179701
12MP0005275_abnormal_skin_tensile2.73127349
13MP0005503_abnormal_tendon_morphology2.72696395
14MP0005670_abnormal_white_adipose2.67372679
15MP0002822_catalepsy2.56732940
16MP0002734_abnormal_mechanical_nocicepti2.54927253
17MP0005423_abnormal_somatic_nervous2.50661308
18MP0001486_abnormal_startle_reflex2.39500298
19MP0002735_abnormal_chemical_nociception2.38960330
20MP0002272_abnormal_nervous_system2.36935578
21MP0002736_abnormal_nociception_after2.29285527
22MP0001440_abnormal_grooming_behavior2.15689836
23MP0004272_abnormal_basement_membrane2.12478146
24MP0001501_abnormal_sleep_pattern2.01509744
25MP0002067_abnormal_sensory_capabilities1.93952089
26MP0000778_abnormal_nervous_system1.90025020
27MP0009780_abnormal_chondrocyte_physiolo1.88521782
28MP0002638_abnormal_pupillary_reflex1.87857611
29MP0005666_abnormal_adipose_tissue1.86095806
30MP0002733_abnormal_thermal_nociception1.85684961
31MP0002971_abnormal_brown_adipose1.82582860
32MP0002557_abnormal_social/conspecific_i1.79899603
33MP0005386_behavior/neurological_phenoty1.79897718
34MP0004924_abnormal_behavior1.79897718
35MP0001970_abnormal_pain_threshold1.78758772
36MP0002184_abnormal_innervation1.76924951
37MP0001958_emphysema1.76006539
38MP0001984_abnormal_olfaction1.75598966
39MP0000013_abnormal_adipose_tissue1.71426634
40MP0008569_lethality_at_weaning1.71323133
41MP0003690_abnormal_glial_cell1.67121271
42MP0010368_abnormal_lymphatic_system1.66861149
43MP0003787_abnormal_imprinting1.62344230
44MP0002837_dystrophic_cardiac_calcinosis1.62199487
45MP0008004_abnormal_stomach_pH1.61164868
46MP0005646_abnormal_pituitary_gland1.60206706
47MP0004811_abnormal_neuron_physiology1.60151764
48MP0003279_aneurysm1.58267354
49MP0003329_amyloid_beta_deposits1.56819209
50MP0005375_adipose_tissue_phenotype1.56751670
51MP0005410_abnormal_fertilization1.56676100
52MP0003879_abnormal_hair_cell1.53694982
53MP0004145_abnormal_muscle_electrophysio1.51381546
54MP0001188_hyperpigmentation1.51223838
55MP0006276_abnormal_autonomic_nervous1.50551024
56MP0003011_delayed_dark_adaptation1.49108354
57MP0001529_abnormal_vocalization1.49021618
58MP0000955_abnormal_spinal_cord1.45511323
59MP0001661_extended_life_span1.42917821
60MP0000751_myopathy1.42805946
61MP0000003_abnormal_adipose_tissue1.39289567
62MP0003705_abnormal_hypodermis_morpholog1.37472513
63MP0004858_abnormal_nervous_system1.35019791
64MP0003646_muscle_fatigue1.34174626
65MP0002882_abnormal_neuron_morphology1.33214551
66MP0005595_abnormal_vascular_smooth1.32668938
67MP0002066_abnormal_motor_capabilities/c1.32579676
68MP0002909_abnormal_adrenal_gland1.29324901
69MP0004215_abnormal_myocardial_fiber1.28176321
70MP0002102_abnormal_ear_morphology1.27708199
71MP0002108_abnormal_muscle_morphology1.24045720
72MP0005409_darkened_coat_color1.23801989
73MP0008877_abnormal_DNA_methylation1.22133509
74MP0002295_abnormal_pulmonary_circulatio1.21422980
75MP0004233_abnormal_muscle_weight1.17276096
76MP0003633_abnormal_nervous_system1.17015743
77MP0010329_abnormal_lipoprotein_level1.16862706
78MP0002152_abnormal_brain_morphology1.12230453
79MP0000569_abnormal_digit_pigmentation1.12072964
80MP0001502_abnormal_circadian_rhythm1.10568363
81MP0001905_abnormal_dopamine_level1.07831906
82MP0002133_abnormal_respiratory_system1.06389449
83MP0005388_respiratory_system_phenotype1.06389449
84MP0004085_abnormal_heartbeat1.04595183
85MP0005508_abnormal_skeleton_morphology1.04211397
86MP0004885_abnormal_endolymph1.04085261
87MP0003631_nervous_system_phenotype1.03498208
88MP0005334_abnormal_fat_pad1.02185303
89MP0001542_abnormal_bone_strength1.02028197
90MP0004142_abnormal_muscle_tone1.01220366
91MP0000534_abnormal_ureter_morphology1.00949290
92MP0004484_altered_response_of1.00089444
93MP0003283_abnormal_digestive_organ0.99672764
94MP0003698_abnormal_male_reproductive0.96933091
95MP0005645_abnormal_hypothalamus_physiol0.96401332
96MP0000462_abnormal_digestive_system0.93218611
97MP0000920_abnormal_myelination0.93104858
98MP0000604_amyloidosis0.91528839
99MP0005551_abnormal_eye_electrophysiolog0.90415370
100MP0003942_abnormal_urinary_system0.89336652
101MP0003868_abnormal_feces_composition0.87916781
102MP0002896_abnormal_bone_mineralization0.87551747
103MP0009384_cardiac_valve_regurgitation0.87429856
104MP0002653_abnormal_ependyma_morphology0.86891871
105MP0010386_abnormal_urinary_bladder0.86253363
106MP0004185_abnormal_adipocyte_glucose0.85877013
107MP0005623_abnormal_meninges_morphology0.85579976
108MP0002069_abnormal_eating/drinking_beha0.84150817
109MP0000631_abnormal_neuroendocrine_gland0.84146785
110MP0000767_abnormal_smooth_muscle0.83332094
111MP0000538_abnormal_urinary_bladder0.82474700
112MP0004510_myositis0.82421496
113MP0008872_abnormal_physiological_respon0.81609023
114MP0004742_abnormal_vestibular_system0.80689600
115MP0003122_maternal_imprinting0.80661600
116MP0004130_abnormal_muscle_cell0.80253965
117MP0001177_atelectasis0.80183999
118MP0009115_abnormal_fat_cell0.80150853
119MP0008874_decreased_physiological_sensi0.80020078
120MP0003950_abnormal_plasma_membrane0.78825154
121MP0003091_abnormal_cell_migration0.78693126
122MP0006138_congestive_heart_failure0.78362314
123MP0005448_abnormal_energy_balance0.77719539
124MP0003137_abnormal_impulse_conducting0.77629405
125MP0002229_neurodegeneration0.77160255
126MP0005620_abnormal_muscle_contractility0.76540264
127MP0001963_abnormal_hearing_physiology0.76026127
128MP0002752_abnormal_somatic_nervous0.75950951
129MP0002970_abnormal_white_adipose0.75285979
130MP0003959_abnormal_lean_body0.74290923
131MP0002876_abnormal_thyroid_physiology0.74169814
132MP0003632_abnormal_nervous_system0.74118461
133MP0005535_abnormal_body_temperature0.72519996
134MP0004036_abnormal_muscle_relaxation0.67406822
135MP0001299_abnormal_eye_distance/0.67148628
136MP0005171_absent_coat_pigmentation0.65666757
137MP0003861_abnormal_nervous_system0.65506899
138MP0005187_abnormal_penis_morphology0.65368720
139MP0005394_taste/olfaction_phenotype0.62723447
140MP0005499_abnormal_olfactory_system0.62723447
141MP0001929_abnormal_gametogenesis0.62280464
142MP0000015_abnormal_ear_pigmentation0.60714795
143MP0002234_abnormal_pharynx_morphology0.60363925
144MP0000747_muscle_weakness0.60216689
145MP0008961_abnormal_basal_metabolism0.58700993
146MP0003634_abnormal_glial_cell0.55633630
147MP0002161_abnormal_fertility/fecundity0.53777475

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.25586410
2Myokymia (HP:0002411)5.51371695
3Focal seizures (HP:0007359)5.18566448
4Epileptic encephalopathy (HP:0200134)4.71731468
5Protrusio acetabuli (HP:0003179)4.27257728
6Visual hallucinations (HP:0002367)4.25407992
7Febrile seizures (HP:0002373)4.24387727
8Dynein arm defect of respiratory motile cilia (HP:0012255)4.21596319
9Absent/shortened dynein arms (HP:0200106)4.21596319
10Progressive cerebellar ataxia (HP:0002073)4.13914154
11Atonic seizures (HP:0010819)4.12846477
12Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.82141239
13Aortic aneurysm (HP:0004942)3.76924416
14Broad-based gait (HP:0002136)3.75621982
15Absence seizures (HP:0002121)3.57422997
16Gaze-evoked nystagmus (HP:0000640)3.47006815
17Hyperventilation (HP:0002883)3.44574885
18Generalized tonic-clonic seizures (HP:0002069)3.41843443
19Vascular tortuosity (HP:0004948)3.39018258
20Dialeptic seizures (HP:0011146)3.31896043
21Truncal ataxia (HP:0002078)3.09738613
22Abnormal respiratory motile cilium physiology (HP:0012261)3.08923665
23Arterial tortuosity (HP:0005116)3.06004194
24Poor eye contact (HP:0000817)3.01989860
25Action tremor (HP:0002345)3.01873464
26Premature rupture of membranes (HP:0001788)2.98497034
27Aortic dissection (HP:0002647)2.96997837
28Gait imbalance (HP:0002141)2.93128442
29Genetic anticipation (HP:0003743)2.88301692
30Impaired smooth pursuit (HP:0007772)2.85733085
31Abnormal respiratory motile cilium morphology (HP:0005938)2.82898749
32Abnormal respiratory epithelium morphology (HP:0012253)2.82898749
33Urinary bladder sphincter dysfunction (HP:0002839)2.82374361
34Drooling (HP:0002307)2.81923564
35Excessive salivation (HP:0003781)2.81923564
36Mutism (HP:0002300)2.80526339
37Impaired vibration sensation in the lower limbs (HP:0002166)2.79406458
38Abnormal ciliary motility (HP:0012262)2.73879844
39Dysdiadochokinesis (HP:0002075)2.71958448
40Skin nodule (HP:0200036)2.65096971
41Abnormal social behavior (HP:0012433)2.63399003
42Impaired social interactions (HP:0000735)2.63399003
43Rhinitis (HP:0012384)2.56531702
44Dysmetria (HP:0001310)2.55219264
45Abnormality of the lower motor neuron (HP:0002366)2.52009148
46Abnormality of ocular smooth pursuit (HP:0000617)2.51638260
47Supranuclear gaze palsy (HP:0000605)2.51207648
48Ankle clonus (HP:0011448)2.51171587
49Hemiparesis (HP:0001269)2.50503084
50Absent speech (HP:0001344)2.49779995
51Amblyopia (HP:0000646)2.46222835
52Turricephaly (HP:0000262)2.45486628
53Broad metatarsal (HP:0001783)2.45142011
54Shallow orbits (HP:0000586)2.44220500
55Amyotrophic lateral sclerosis (HP:0007354)2.43831467
56Intention tremor (HP:0002080)2.40712851
57Hypoplasia of the iris (HP:0007676)2.39922827
58Progressive inability to walk (HP:0002505)2.37518253
59Congenital primary aphakia (HP:0007707)2.36218724
60Overgrowth (HP:0001548)2.34291746
61Fetal akinesia sequence (HP:0001989)2.33459477
62Depression (HP:0000716)2.33369754
63Medial flaring of the eyebrow (HP:0010747)2.33341595
64Urinary urgency (HP:0000012)2.32995360
65Abnormal eating behavior (HP:0100738)2.31516976
66Degeneration of the lateral corticospinal tracts (HP:0002314)2.31245658
67Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.31245658
68Insomnia (HP:0100785)2.30928308
69Wormian bones (HP:0002645)2.30177013
70Follicular hyperkeratosis (HP:0007502)2.28700552
71Cerebral aneurysm (HP:0004944)2.28504282
72Dysmetric saccades (HP:0000641)2.28307061
73Inability to walk (HP:0002540)2.27284330
74Epileptiform EEG discharges (HP:0011182)2.25535409
75Papilledema (HP:0001085)2.24213044
76Stereotypic behavior (HP:0000733)2.21673791
77Acanthosis nigricans (HP:0000956)2.20523956
78Hyperlipoproteinemia (HP:0010980)2.20274680
79Striae distensae (HP:0001065)2.19119066
80Diplopia (HP:0000651)2.19028547
81Abnormality of binocular vision (HP:0011514)2.19028547
82Abnormality of the corticospinal tract (HP:0002492)2.18656562
83Insidious onset (HP:0003587)2.17444334
84Termporal pattern (HP:0011008)2.17444334
85Anxiety (HP:0000739)2.16301741
86Torticollis (HP:0000473)2.15795862
87Epidermoid cyst (HP:0200040)2.14948283
88Soft skin (HP:0000977)2.13131667
89Nephrogenic diabetes insipidus (HP:0009806)2.12525704
90Postural instability (HP:0002172)2.10230030
91EEG with generalized epileptiform discharges (HP:0011198)2.10117378
92Ankle contracture (HP:0006466)2.07951355
93Spastic gait (HP:0002064)2.06935542
94Inappropriate behavior (HP:0000719)2.06588265
95Scanning speech (HP:0002168)2.06450396
96Increased variability in muscle fiber diameter (HP:0003557)2.06247690
97Cerebral inclusion bodies (HP:0100314)2.04980247
98Bladder diverticulum (HP:0000015)2.04285500
99Elfin facies (HP:0004428)2.03804319
100Retinal dysplasia (HP:0007973)2.00626077
101Polyphagia (HP:0002591)1.99697085
102Neurofibrillary tangles (HP:0002185)1.99050971
103Generalized myoclonic seizures (HP:0002123)1.98527008
104Bundle branch block (HP:0011710)1.98520657
105Neoplasm of the heart (HP:0100544)1.98404984
106Mitral stenosis (HP:0001718)1.97374525
107Sensory axonal neuropathy (HP:0003390)1.96690784
108Ventricular fibrillation (HP:0001663)1.95487016
109Hypsarrhythmia (HP:0002521)1.95145753
110Abnormality of dentin (HP:0010299)1.94442311
111Pointed chin (HP:0000307)1.94184171
112Specific learning disability (HP:0001328)1.93992259
113Focal dystonia (HP:0004373)1.93181451
114Coronal craniosynostosis (HP:0004440)1.92908729
115Lower limb amyotrophy (HP:0007210)1.92512119
116Impaired vibratory sensation (HP:0002495)1.92509979
117Papillary thyroid carcinoma (HP:0002895)1.92501124
118Complement deficiency (HP:0004431)1.91446666
119Limb dystonia (HP:0002451)1.88994370
120Lower limb muscle weakness (HP:0007340)1.88423067
121Type II lissencephaly (HP:0007260)1.88310697
122Overriding aorta (HP:0002623)1.88008684
123Abnormality of saccadic eye movements (HP:0000570)1.85190302
124Genital tract atresia (HP:0001827)1.84615388
125Gait ataxia (HP:0002066)1.83680114
126Renovascular hypertension (HP:0100817)1.83275942
127Aplasia involving bones of the extremities (HP:0009825)1.83265256
128Aplasia involving bones of the upper limbs (HP:0009823)1.83265256
129Aplasia of the phalanges of the hand (HP:0009802)1.83265256
130Poor coordination (HP:0002370)1.81926310
131Infertility (HP:0000789)1.81595446
132Bradykinesia (HP:0002067)1.80955546
133Vaginal atresia (HP:0000148)1.80625110
134Postural tremor (HP:0002174)1.80239871
135Abnormal EKG (HP:0003115)1.80198651
136Growth hormone excess (HP:0000845)1.77559721
137Neonatal short-limb short stature (HP:0008921)1.75058626
138Hammertoe (HP:0001765)1.74986178
139Testicular neoplasm (HP:0010788)1.73152553
140Abnormality of the pulmonary veins (HP:0011718)1.71387166
141Relative macrocephaly (HP:0004482)1.69564389
142Vertebral compression fractures (HP:0002953)1.69516320
143Anomalous pulmonary venous return (HP:0010772)1.68755408
144Joint laxity (HP:0001388)1.67704768
145Dilatation of the ascending aorta (HP:0005111)1.66146241
146Aneurysm (HP:0002617)1.66080757
147Craniofacial dystonia (HP:0012179)1.65997315
148Bowel diverticulosis (HP:0005222)1.65693507
149Pulmonary artery stenosis (HP:0004415)1.65644991
150Long toe (HP:0010511)1.65111529
151Osteolytic defects of the phalanges of the hand (HP:0009771)1.65108285
152Osteolytic defects of the hand bones (HP:0009699)1.65108285
153Oligomenorrhea (HP:0000876)1.64545312
154Aortic regurgitation (HP:0001659)1.63835855
155Wide anterior fontanel (HP:0000260)1.62685096
156Horizontal nystagmus (HP:0000666)1.62509398
157Buphthalmos (HP:0000557)1.62186348
158Obstructive sleep apnea (HP:0002870)1.61879989
159Upper motor neuron abnormality (HP:0002127)1.61631480

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.77866698
2NTRK34.49133444
3MAP3K93.83940668
4MARK13.83649740
5MAP3K43.15791741
6MAP2K72.72781321
7CASK2.49004482
8DAPK22.22729057
9MINK12.20284861
10DDR22.03927145
11PDGFRA2.02853609
12NTRK22.02038889
13PDK41.95989750
14PDK31.95989750
15MYLK1.90080466
16PAK61.87244646
17MAP2K41.82802703
18KSR21.80153836
19TNIK1.73364122
20MAPK131.66075474
21KSR11.59485136
22ADRBK21.59480876
23PLK21.56142850
24PRKD31.55287294
25RIPK41.53375661
26CAMKK11.46202343
27TGFBR21.44550640
28MAP3K121.42319505
29PHKG11.40908755
30PHKG21.40908755
31DAPK11.33814574
32CDK51.32361958
33FES1.29943419
34LATS21.29387407
35STK381.29319583
36PNCK1.28632951
37NTRK11.28573931
38PRPF4B1.25802600
39MAP3K61.22519228
40EPHB21.16986983
41TYRO31.15148236
42TAOK11.12605122
43SIK21.12467321
44SIK11.09068473
45PRKCG1.09033146
46CAMK2A1.07356124
47CAMK1D1.07163255
48PDK21.00846167
49GRK70.99782395
50GRK50.99263582
51CCNB10.99144723
52MAPK70.98203081
53NEK90.97586383
54LMTK20.96271194
55LATS10.95391371
56CDK190.94968810
57MAP3K20.93335916
58JAK10.90387829
59CAMKK20.88402249
60MOS0.87700519
61SGK20.85650004
62PTK2B0.85473089
63MARK20.83413102
64MAP2K10.82344122
65PTK20.82294959
66AKT30.80267513
67RET0.79410035
68SGK4940.78657961
69SGK2230.78657961
70MAPK40.78580917
71BMPR20.78123068
72TIE10.77539008
73MET0.76185949
74STK110.75513037
75DMPK0.75198598
76CAMK10.73846248
77SGK10.73671367
78CDK180.73316544
79RAF10.73275482
80CAMK2B0.72044549
81CDK150.71174075
82TESK10.70522593
83FRK0.70465752
84ARAF0.70203777
85PAK30.68550576
86CDK140.67035978
87CSNK1G20.64833533
88FGFR20.62818910
89SGK30.60732688
90BRD40.60208999
91EPHA30.59806482
92OXSR10.58501869
93CDK11A0.58294402
94RPS6KA20.57826428
95PAK20.57668998
96MAP3K130.57403522
97ADRBK10.57287403
98PDK10.57139054
99DYRK1A0.57011681
100UHMK10.52983716
101PINK10.52209530
102PRKCH0.52060598
103PRKCE0.50976689
104PKN10.49998485
105ROCK20.49793007
106TRIB30.49495043
107ABL20.48874958
108MUSK0.48119201
109PDPK10.47952410
110TAOK20.46973674
111MAPK120.46506804
112CAMK2D0.46180216
113FER0.45865788
114RPS6KA30.42907722
115ERBB30.42879698
116PRKCZ0.41426744
117NEK60.41027454
118BRAF0.38913927
119FYN0.38842758
120CAMK1G0.37561672
121PRKG10.37482517
122RIPK10.37464270
123MAPK100.34918074
124CDC42BPA0.34461697
125WNK10.33660959
126MAP3K10.32616181
127PDGFRB0.32475347
128CAMK2G0.32150459
129MAP3K50.30638018
130FGR0.28806383
131CAMK40.28742603

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.78071246
2Synaptic vesicle cycle_Homo sapiens_hsa047212.92047695
3Circadian entrainment_Homo sapiens_hsa047132.77496615
4Long-term potentiation_Homo sapiens_hsa047202.74607273
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.67790542
6Glutamatergic synapse_Homo sapiens_hsa047242.64592025
7Olfactory transduction_Homo sapiens_hsa047402.53250966
8Morphine addiction_Homo sapiens_hsa050322.52451445
9Amphetamine addiction_Homo sapiens_hsa050312.49999487
10GABAergic synapse_Homo sapiens_hsa047272.46514011
11Dopaminergic synapse_Homo sapiens_hsa047282.12913573
12Salivary secretion_Homo sapiens_hsa049702.05747526
13Taste transduction_Homo sapiens_hsa047421.90921392
14Renin secretion_Homo sapiens_hsa049241.90886672
15Insulin secretion_Homo sapiens_hsa049111.86185018
16Cholinergic synapse_Homo sapiens_hsa047251.85599849
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.81561557
18Gastric acid secretion_Homo sapiens_hsa049711.81467062
19Long-term depression_Homo sapiens_hsa047301.79339876
20Oxytocin signaling pathway_Homo sapiens_hsa049211.77713438
21Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.77350363
22PPAR signaling pathway_Homo sapiens_hsa033201.75892117
23Serotonergic synapse_Homo sapiens_hsa047261.71749159
24Calcium signaling pathway_Homo sapiens_hsa040201.69970130
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.63332840
26Cocaine addiction_Homo sapiens_hsa050301.59531527
27Fatty acid biosynthesis_Homo sapiens_hsa000611.56538175
28Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.50038231
29GnRH signaling pathway_Homo sapiens_hsa049121.44663040
30cAMP signaling pathway_Homo sapiens_hsa040241.39270073
31Gap junction_Homo sapiens_hsa045401.30863413
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.29415524
33Axon guidance_Homo sapiens_hsa043601.28207422
34Collecting duct acid secretion_Homo sapiens_hsa049661.25082415
35ECM-receptor interaction_Homo sapiens_hsa045121.24908637
36Estrogen signaling pathway_Homo sapiens_hsa049151.23451355
37Type II diabetes mellitus_Homo sapiens_hsa049301.22994820
38Glycerolipid metabolism_Homo sapiens_hsa005611.20641608
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.19687451
40Phosphatidylinositol signaling system_Homo sapiens_hsa040701.19632143
41Cardiac muscle contraction_Homo sapiens_hsa042601.18604997
42cGMP-PKG signaling pathway_Homo sapiens_hsa040221.17636060
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.15745070
44Dorso-ventral axis formation_Homo sapiens_hsa043201.15357433
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.15041939
46Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.14413748
47ErbB signaling pathway_Homo sapiens_hsa040121.13831843
48Oocyte meiosis_Homo sapiens_hsa041141.07641581
49Glioma_Homo sapiens_hsa052141.05632068
50Dilated cardiomyopathy_Homo sapiens_hsa054141.03439513
51Vascular smooth muscle contraction_Homo sapiens_hsa042701.02385504
52Prion diseases_Homo sapiens_hsa050201.01630159
53Focal adhesion_Homo sapiens_hsa045100.97926338
54Melanogenesis_Homo sapiens_hsa049160.96954814
55Phenylalanine metabolism_Homo sapiens_hsa003600.90518815
56Choline metabolism in cancer_Homo sapiens_hsa052310.85970432
57Phospholipase D signaling pathway_Homo sapiens_hsa040720.85170443
58beta-Alanine metabolism_Homo sapiens_hsa004100.81631163
59Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.79572451
60MAPK signaling pathway_Homo sapiens_hsa040100.77902875
61Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.77217306
62Pancreatic secretion_Homo sapiens_hsa049720.75914120
63Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.74646042
64AMPK signaling pathway_Homo sapiens_hsa041520.74548244
65Circadian rhythm_Homo sapiens_hsa047100.74126968
66Glucagon signaling pathway_Homo sapiens_hsa049220.73825818
67Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.72687806
68Protein digestion and absorption_Homo sapiens_hsa049740.72378479
69Phototransduction_Homo sapiens_hsa047440.71981280
70Adipocytokine signaling pathway_Homo sapiens_hsa049200.71510313
71Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.69540172
72Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.66915443
73VEGF signaling pathway_Homo sapiens_hsa043700.66832291
74Pyruvate metabolism_Homo sapiens_hsa006200.66663053
75Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.65893447
76Fatty acid metabolism_Homo sapiens_hsa012120.65478784
77Vibrio cholerae infection_Homo sapiens_hsa051100.65183658
78Ras signaling pathway_Homo sapiens_hsa040140.65145632
79Ovarian steroidogenesis_Homo sapiens_hsa049130.63851647
80Histidine metabolism_Homo sapiens_hsa003400.63091734
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61557548
82Amoebiasis_Homo sapiens_hsa051460.61557390
83Thyroid hormone synthesis_Homo sapiens_hsa049180.61194985
84Glycosaminoglycan degradation_Homo sapiens_hsa005310.60774237
85Proteoglycans in cancer_Homo sapiens_hsa052050.58619316
86Thyroid hormone signaling pathway_Homo sapiens_hsa049190.57940233
87Fatty acid elongation_Homo sapiens_hsa000620.57689429
88Neurotrophin signaling pathway_Homo sapiens_hsa047220.56749818
89Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.56454067
90Rap1 signaling pathway_Homo sapiens_hsa040150.54779347
91Tyrosine metabolism_Homo sapiens_hsa003500.54741946
92Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54361425
93Endometrial cancer_Homo sapiens_hsa052130.53755483
94Wnt signaling pathway_Homo sapiens_hsa043100.53667307
95Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.53602653
96AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.53149147
97mTOR signaling pathway_Homo sapiens_hsa041500.52370691
98Carbohydrate digestion and absorption_Homo sapiens_hsa049730.52214774
99Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.51299403
100Inositol phosphate metabolism_Homo sapiens_hsa005620.50938424
101Renal cell carcinoma_Homo sapiens_hsa052110.50916172
102Propanoate metabolism_Homo sapiens_hsa006400.50828712
103Fatty acid degradation_Homo sapiens_hsa000710.47985563
104Insulin signaling pathway_Homo sapiens_hsa049100.47747897
105Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47688546
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.47341721
107Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.46698829
108Alcoholism_Homo sapiens_hsa050340.43287011
109Adherens junction_Homo sapiens_hsa045200.42455694
110Colorectal cancer_Homo sapiens_hsa052100.41598135
111Alzheimers disease_Homo sapiens_hsa050100.40847865
112Melanoma_Homo sapiens_hsa052180.37757227
113Renin-angiotensin system_Homo sapiens_hsa046140.36989460
114Non-small cell lung cancer_Homo sapiens_hsa052230.36706016
115ABC transporters_Homo sapiens_hsa020100.36642729
116Platelet activation_Homo sapiens_hsa046110.35890327
117Endocytosis_Homo sapiens_hsa041440.33708286
118Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.30282836
119Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.28478017
120Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.27593924
121Glycerophospholipid metabolism_Homo sapiens_hsa005640.26907750
122Bile secretion_Homo sapiens_hsa049760.26363552
123Regulation of actin cytoskeleton_Homo sapiens_hsa048100.25954727
124Huntingtons disease_Homo sapiens_hsa050160.24037722
125Chemokine signaling pathway_Homo sapiens_hsa040620.23799754
126Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.23489555
127Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.22710136
128Prolactin signaling pathway_Homo sapiens_hsa049170.22371344

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