ARHGDIB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1leukocyte aggregation (GO:0070486)5.14506208
2positive regulation of gamma-delta T cell activation (GO:0046645)5.01265518
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.80954264
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.80954264
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.67852244
6antigen processing and presentation of endogenous antigen (GO:0019883)4.49737785
7positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.40243530
8regulation of B cell receptor signaling pathway (GO:0050855)4.35482421
9negative regulation of phagocytosis (GO:0050765)4.32672111
10Arp2/3 complex-mediated actin nucleation (GO:0034314)4.32510881
11ribosomal small subunit assembly (GO:0000028)4.30552678
12positive T cell selection (GO:0043368)4.18369770
13positive regulation of B cell differentiation (GO:0045579)3.79995125
14mast cell activation (GO:0045576)3.78751709
15respiratory burst (GO:0045730)3.74650562
16neutrophil activation involved in immune response (GO:0002283)3.73402980
17regulation of B cell differentiation (GO:0045577)3.70191566
18T cell selection (GO:0045058)3.69962400
19cellular response to zinc ion (GO:0071294)3.69105336
20positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.65988120
21immunoglobulin mediated immune response (GO:0016064)3.65183818
22detection of bacterium (GO:0016045)3.64223105
23detection of other organism (GO:0098543)3.58401572
24regulation of gamma-delta T cell differentiation (GO:0045586)3.55768684
25cytidine metabolic process (GO:0046087)3.53922711
26cytidine catabolic process (GO:0006216)3.53922711
27cytidine deamination (GO:0009972)3.53922711
28T cell migration (GO:0072678)3.48074322
29positive regulation by symbiont of host defense response (GO:0052509)3.42417140
30modulation by symbiont of host defense response (GO:0052031)3.42417140
31modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.42417140
32modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.42417140
33positive regulation by organism of defense response of other organism involved in symbiotic interact3.42417140
34modulation by symbiont of host immune response (GO:0052553)3.42417140
35B cell receptor signaling pathway (GO:0050853)3.40452753
36regulation of gamma-delta T cell activation (GO:0046643)3.36194826
37antigen processing and presentation via MHC class Ib (GO:0002475)3.33760828
38response to peptidoglycan (GO:0032494)3.31379064
39negative regulation of interleukin-12 production (GO:0032695)3.31124188
40positive regulation of granulocyte differentiation (GO:0030854)3.30797239
41regulation of antigen processing and presentation (GO:0002577)3.29874566
42positive regulation of antigen processing and presentation (GO:0002579)3.29783027
43defense response to protozoan (GO:0042832)3.29741447
44regulation of regulatory T cell differentiation (GO:0045589)3.29487909
45neutrophil mediated immunity (GO:0002446)3.29388914
46negative T cell selection (GO:0043383)3.28764898
47negative thymic T cell selection (GO:0045060)3.27681146
48positive regulation of T cell mediated cytotoxicity (GO:0001916)3.25358181
49negative regulation of lymphocyte mediated immunity (GO:0002707)3.21997428
50regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.20762009
51regulation of natural killer cell mediated immunity (GO:0002715)3.20762009
52regulation of T cell tolerance induction (GO:0002664)3.20343284
53regulation of T cell mediated cytotoxicity (GO:0001914)3.18751547
54actin nucleation (GO:0045010)3.17448041
55response to protozoan (GO:0001562)3.16996985
56pyrimidine ribonucleoside catabolic process (GO:0046133)3.15849573
57T cell receptor signaling pathway (GO:0050852)3.14012938
58regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.13309509
59Peyers patch development (GO:0048541)3.12051143
60mucosal-associated lymphoid tissue development (GO:0048537)3.12051143
61B cell mediated immunity (GO:0019724)3.11818375
62negative regulation of leukocyte mediated immunity (GO:0002704)3.11126784
63regulation of dendritic cell antigen processing and presentation (GO:0002604)3.08163516
64interferon-gamma production (GO:0032609)3.07449573
65regulation of tolerance induction (GO:0002643)3.07063076
66negative regulation of T cell mediated immunity (GO:0002710)3.07004872
67negative regulation of cell killing (GO:0031342)3.06129064
68negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.06129064
69cellular extravasation (GO:0045123)3.05216646
70modulation of growth of symbiont involved in interaction with host (GO:0044144)3.05191716
71regulation of growth of symbiont in host (GO:0044126)3.05191716
72negative regulation of growth of symbiont in host (GO:0044130)3.05191716
73negative regulation of growth of symbiont involved in interaction with host (GO:0044146)3.05191716
74regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.04994096
75positive thymic T cell selection (GO:0045059)3.04165497
76positive regulation of lamellipodium assembly (GO:0010592)3.04095708
77regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.03507551
78negative regulation of T cell apoptotic process (GO:0070233)3.02576322
79regulation of mast cell degranulation (GO:0043304)2.99919897
80sequestering of actin monomers (GO:0042989)2.98030383
81T cell costimulation (GO:0031295)2.98010629
82response to fungus (GO:0009620)2.97807378
83DNA deamination (GO:0045006)2.97355788
84regulation of T cell receptor signaling pathway (GO:0050856)2.97329474
85myeloid dendritic cell activation (GO:0001773)2.94972636
86telomere maintenance via semi-conservative replication (GO:0032201)2.94934108
87neutrophil activation (GO:0042119)2.94086332
88lymphocyte costimulation (GO:0031294)2.94001003
89regulation of leukocyte mediated cytotoxicity (GO:0001910)2.92993211
90positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.92418641
91response to interferon-beta (GO:0035456)2.90423054
92megakaryocyte development (GO:0035855)2.90092730
93response to type I interferon (GO:0034340)2.89494939
94type I interferon signaling pathway (GO:0060337)2.88500221
95cellular response to type I interferon (GO:0071357)2.88500221
96T cell homeostasis (GO:0043029)2.87876946
97cellular response to interferon-beta (GO:0035458)2.86882598
98defense response to fungus (GO:0050832)2.86258023
99positive regulation of tolerance induction (GO:0002645)2.85249915
100regulation of mast cell activation (GO:0033003)2.84826108
101positive regulation of mast cell activation (GO:0033005)2.84802442
102response to interleukin-15 (GO:0070672)2.84763403
103leukocyte cell-cell adhesion (GO:0007159)2.84395359
104disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.84239417
105killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.84239417
106macrophage activation involved in immune response (GO:0002281)2.83229774
107tolerance induction (GO:0002507)2.82457471
108mast cell activation involved in immune response (GO:0002279)2.82134441
109mast cell degranulation (GO:0043303)2.82134441
110regulation of interleukin-2 biosynthetic process (GO:0045076)2.82111318
111negative regulation of innate immune response (GO:0045824)2.81228441
112interferon-gamma-mediated signaling pathway (GO:0060333)2.80345534
113response to host immune response (GO:0052572)2.78656383
114response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.78656383
115regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.78239559
116DNA strand elongation involved in DNA replication (GO:0006271)2.77389038
117cellular response to interleukin-15 (GO:0071350)2.77128572
118leukocyte degranulation (GO:0043299)2.76732157
119positive regulation of isotype switching (GO:0045830)2.72816253
120myeloid leukocyte mediated immunity (GO:0002444)2.70099934
121angiogenesis involved in wound healing (GO:0060055)2.69286764
122DNA strand elongation (GO:0022616)2.69026793
123regulation of interleukin-12 biosynthetic process (GO:0045075)2.67508386
124granulocyte activation (GO:0036230)2.67030637
125telomere maintenance via recombination (GO:0000722)2.66280076
126myeloid cell activation involved in immune response (GO:0002275)2.66100817
127antigen receptor-mediated signaling pathway (GO:0050851)2.63499614
128viral transcription (GO:0019083)2.60426008
129necroptotic process (GO:0070266)2.59073882
130leukocyte mediated cytotoxicity (GO:0001909)2.58554415
131NIK/NF-kappaB signaling (GO:0038061)2.57655192
132regulation of response to interferon-gamma (GO:0060330)2.56800111
133negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.56496921
134lymphocyte homeostasis (GO:0002260)2.56172524
135positive regulation of macrophage differentiation (GO:0045651)2.55134027
136regulation of necroptotic process (GO:0060544)2.54473736
137positive regulation of lamellipodium organization (GO:1902745)2.54249137
138regulation of alpha-beta T cell proliferation (GO:0046640)2.54207395
139mature B cell differentiation involved in immune response (GO:0002313)2.52991922
140thymic T cell selection (GO:0045061)2.52436435
141regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.52265081
142translational termination (GO:0006415)2.48553701
143definitive hemopoiesis (GO:0060216)2.47828158
144positive regulation of alpha-beta T cell proliferation (GO:0046641)2.44847235
145regulation of interferon-beta biosynthetic process (GO:0045357)2.44037217
146positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.44031622
147myeloid dendritic cell differentiation (GO:0043011)2.41113829
148natural killer cell activation (GO:0030101)2.40773806
149production of molecular mediator involved in inflammatory response (GO:0002532)2.40616750

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.90354282
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.11369595
3IRF8_21731497_ChIP-ChIP_J774_Mouse3.49208238
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.46801325
5* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.40965931
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.36409003
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.32837297
8BP1_19119308_ChIP-ChIP_Hs578T_Human3.05488775
9SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.98154362
10* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.83301647
11MYB_21317192_ChIP-Seq_ERMYB_Mouse2.80646549
12SCL_19346495_ChIP-Seq_HPC-7_Human2.69029809
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.65374739
14EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.62075253
15* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.54530635
16STAT4_19710469_ChIP-ChIP_TH1__Mouse2.46944922
17* SPI1_23547873_ChIP-Seq_NB4_Human2.44859376
18EGR1_19374776_ChIP-ChIP_THP-1_Human2.42774521
19MYC_22102868_ChIP-Seq_BL_Human2.38750095
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.35995579
21FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.35167664
22VDR_21846776_ChIP-Seq_THP-1_Human2.34254701
23MYB_26560356_Chip-Seq_TH2_Human2.26978475
24SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.25894138
25NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.20749390
26IRF8_27001747_Chip-Seq_BMDM_Mouse2.20414758
27STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.11574839
28E2F4_17652178_ChIP-ChIP_JURKAT_Human2.10977716
29FOXM1_23109430_ChIP-Seq_U2OS_Human2.09173938
30TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.08292685
31ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.04103942
32MAF_26560356_Chip-Seq_TH1_Human2.02914565
33RUNX1_22412390_ChIP-Seq_EML_Mouse1.94561311
34MYB_26560356_Chip-Seq_TH1_Human1.92663065
35SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.90739460
36BRD4_27068464_Chip-Seq_AML-cells_Mouse1.89328293
37* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.88606809
38VDR_24763502_ChIP-Seq_THP-1_Human1.86031341
39NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.85180863
40MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.81271881
41* UTX_26944678_Chip-Seq_JUKART_Human1.80085817
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.79706375
43RUNX_20019798_ChIP-Seq_JUKART_Human1.77652063
44SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.76558011
45FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.69474990
46NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.68993330
47ERG_20887958_ChIP-Seq_HPC-7_Mouse1.67945610
48GABP_17652178_ChIP-ChIP_JURKAT_Human1.66384575
49MYC_18555785_ChIP-Seq_MESCs_Mouse1.63561623
50VDR_23849224_ChIP-Seq_CD4+_Human1.62825010
51NOTCH1_21737748_ChIP-Seq_TLL_Human1.59806851
52EST1_17652178_ChIP-ChIP_JURKAT_Human1.59455574
53FOXP3_21729870_ChIP-Seq_TREG_Human1.54964507
54* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.54828456
55CIITA_25753668_ChIP-Seq_RAJI_Human1.47767614
56GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.47341604
57KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.46717632
58* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.45057672
59* LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.43401164
60GATA1_22383799_ChIP-Seq_G1ME_Mouse1.40085766
61BCL6_27268052_Chip-Seq_Bcells_Human1.38592941
62SPI1_23127762_ChIP-Seq_K562_Human1.34960575
63JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.32845254
64* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.32754504
65MYC_18358816_ChIP-ChIP_MESCs_Mouse1.32687019
66FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.31425863
67GATA1_22025678_ChIP-Seq_K562_Human1.30885404
68MAF_26560356_Chip-Seq_TH2_Human1.29039219
69PU_27001747_Chip-Seq_BMDM_Mouse1.26657568
70TCF7_22412390_ChIP-Seq_EML_Mouse1.26349875
71* GATA3_27048872_Chip-Seq_THYMUS_Human1.23506432
72* GATA1_19941827_ChIP-Seq_MEL_Mouse1.23071773
73VDR_24787735_ChIP-Seq_THP-1_Human1.22260419
74VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.21670111
75VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.20596611
76ETS1_20019798_ChIP-Seq_JURKAT_Human1.19977759
77ELK1_19687146_ChIP-ChIP_HELA_Human1.19936452
78CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.16979463
79E2F1_21310950_ChIP-Seq_MCF-7_Human1.16542240
80* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.16537033
81HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.16025458
82ELF1_20517297_ChIP-Seq_JURKAT_Human1.14690040
83MYC_19030024_ChIP-ChIP_MESCs_Mouse1.14646533
84CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.14229399
85PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.13433858
86XRN2_22483619_ChIP-Seq_HELA_Human1.11327357
87* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09992000
88BCOR_27268052_Chip-Seq_Bcells_Human1.08814170
89SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05903519
90SPI1_20517297_ChIP-Seq_HL60_Human1.05865232
91RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.05347622
92CREB1_15753290_ChIP-ChIP_HEK293T_Human1.03976514
93SRF_21415370_ChIP-Seq_HL-1_Mouse1.03482288
94GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.02938720
95PU.1_20513432_ChIP-Seq_Bcells_Mouse1.02878307
96* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.02793367
97P300_27268052_Chip-Seq_Bcells_Human1.02587452
98TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.02539455
99GATA1_19941826_ChIP-Seq_K562_Human1.02392280
100TFEB_21752829_ChIP-Seq_HELA_Human1.00675981
101* GATA3_26560356_Chip-Seq_TH2_Human1.00005816
102PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.99294490
103CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98650226
104NELFA_20434984_ChIP-Seq_ESCs_Mouse0.98457012
105CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97500238
106SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96281017
107GABP_19822575_ChIP-Seq_HepG2_Human0.96198134
108MYC_19079543_ChIP-ChIP_MESCs_Mouse0.95283187
109DCP1A_22483619_ChIP-Seq_HELA_Human0.93939655
110EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.92335619
111PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91330006
112STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.90944838
113STAT1_20625510_ChIP-Seq_HELA_Human0.90778818
114NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.89620295
115CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.89427774
116RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.89181805
117CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.88937248
118PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88818686
119PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.88590941
120* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87964691
121RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87295076
122RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.87204907
123* GATA2_21666600_ChIP-Seq_HMVEC_Human0.85549225
124KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.85405053
125TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.85189242
126KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.84451110
127RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.81777506
128KDM2B_26808549_Chip-Seq_DND41_Human0.81058358
129CTCF_26484167_Chip-Seq_Bcells_Mouse0.80771673

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.16543366
2MP0005671_abnormal_response_to3.52998858
3MP0009785_altered_susceptibility_to3.52361613
4MP0003436_decreased_susceptibility_to3.14025102
5MP0002396_abnormal_hematopoietic_system3.11426530
6MP0003763_abnormal_thymus_physiology3.06306215
7MP0000685_abnormal_immune_system3.05719892
8MP0001800_abnormal_humoral_immune2.87540941
9MP0005025_abnormal_response_to2.85041952
10MP0005000_abnormal_immune_tolerance2.81717250
11MP0002148_abnormal_hypersensitivity_rea2.73240621
12MP0002419_abnormal_innate_immunity2.72708553
13* MP0002420_abnormal_adaptive_immunity2.67726829
14* MP0002452_abnormal_antigen_presenting2.64424516
15* MP0001819_abnormal_immune_cell2.64201417
16MP0002723_abnormal_immune_serum2.58244147
17MP0001790_abnormal_immune_system2.57484400
18MP0005387_immune_system_phenotype2.57484400
19MP0002166_altered_tumor_susceptibility2.51737766
20* MP0002398_abnormal_bone_marrow2.50254193
21MP0005464_abnormal_platelet_physiology2.41799077
22MP0003724_increased_susceptibility_to2.32135671
23* MP0000716_abnormal_immune_system2.22557995
24MP0002405_respiratory_system_inflammati2.19160126
25MP0009333_abnormal_splenocyte_physiolog2.13553960
26MP0002006_tumorigenesis2.11006192
27MP0003303_peritoneal_inflammation2.09061108
28MP0000689_abnormal_spleen_morphology2.08841983
29MP0004808_abnormal_hematopoietic_stem2.06315025
30MP0002722_abnormal_immune_system2.06127648
31MP0001853_heart_inflammation1.97196012
32* MP0002429_abnormal_blood_cell1.94384736
33MP0001545_abnormal_hematopoietic_system1.93520349
34MP0005397_hematopoietic_system_phenotyp1.93520349
35MP0010155_abnormal_intestine_physiology1.88550320
36MP0001873_stomach_inflammation1.83375520
37MP0006082_CNS_inflammation1.79875860
38MP0008057_abnormal_DNA_replication1.78911925
39MP0001845_abnormal_inflammatory_respons1.78207275
40MP0003693_abnormal_embryo_hatching1.77298017
41MP0000703_abnormal_thymus_morphology1.73412229
42MP0000465_gastrointestinal_hemorrhage1.71658070
43MP0000490_abnormal_crypts_of1.70184898
44MP0005174_abnormal_tail_pigmentation1.65648744
45MP0010094_abnormal_chromosome_stability1.63056764
46MP0000858_altered_metastatic_potential1.60940539
47MP0003806_abnormal_nucleotide_metabolis1.59009112
48MP0001533_abnormal_skeleton_physiology1.52228178
49MP0005075_abnormal_melanosome_morpholog1.51520553
50MP0004947_skin_inflammation1.48310612
51MP0003866_abnormal_defecation1.41753803
52MP0002933_joint_inflammation1.37051567
53MP0003172_abnormal_lysosome_physiology1.36329444
54MP0008469_abnormal_protein_level1.34029927
55MP0006054_spinal_hemorrhage1.32218181
56MP0003077_abnormal_cell_cycle1.30921146
57MP0003300_gastrointestinal_ulcer1.28972253
58MP0002019_abnormal_tumor_incidence1.25860516
59MP0009278_abnormal_bone_marrow1.23121629
60MP0002138_abnormal_hepatobiliary_system1.21217413
61MP0003111_abnormal_nucleus_morphology1.19540735
62MP0000343_altered_response_to1.19005499
63MP0003448_altered_tumor_morphology1.18209516
64MP0005058_abnormal_lysosome_morphology1.14052123
65MP0002095_abnormal_skin_pigmentation1.13097925
66MP0008058_abnormal_DNA_repair1.12295963
67MP0008007_abnormal_cellular_replicative1.09196790
68MP0000015_abnormal_ear_pigmentation1.07587900
69MP0002132_abnormal_respiratory_system1.07470316
70MP0003183_abnormal_peptide_metabolism1.06647208
71MP0005310_abnormal_salivary_gland1.04547425
72MP0010307_abnormal_tumor_latency1.03087474
73MP0004957_abnormal_blastocyst_morpholog1.00109697
74MP0009764_decreased_sensitivity_to0.97034416
75MP0001851_eye_inflammation0.95690157
76MP0010352_gastrointestinal_tract_polyps0.93013608
77MP0004510_myositis0.93001418
78MP0003656_abnormal_erythrocyte_physiolo0.92770037
79MP0003186_abnormal_redox_activity0.85698085
80MP0002277_abnormal_respiratory_mucosa0.84326628
81MP0000313_abnormal_cell_death0.83588556
82MP0009763_increased_sensitivity_to0.80916941
83MP0003191_abnormal_cellular_cholesterol0.74086716
84MP0008260_abnormal_autophagy0.72645723
85MP0003045_fibrosis0.72422911
86MP0005023_abnormal_wound_healing0.70357725
87MP0005084_abnormal_gallbladder_morpholo0.69999778
88MP0004883_abnormal_blood_vessel0.69740683
89MP0001663_abnormal_digestive_system0.69319106
90MP0005451_abnormal_body_composition0.67598316
91MP0002998_abnormal_bone_remodeling0.66756663
92MP0001986_abnormal_taste_sensitivity0.64951720
93MP0003075_altered_response_to0.63700571
94MP0002009_preneoplasia0.63389144
95MP0008004_abnormal_stomach_pH0.63267645
96MP0005390_skeleton_phenotype0.62505022
97MP0005166_decreased_susceptibility_to0.62120400
98MP0000371_diluted_coat_color0.60775984
99MP0006036_abnormal_mitochondrial_physio0.59396487
100MP0002693_abnormal_pancreas_physiology0.59121154
101MP0000604_amyloidosis0.57760537
102MP0003252_abnormal_bile_duct0.57660860
103MP0005645_abnormal_hypothalamus_physiol0.57547874
104MP0003943_abnormal_hepatobiliary_system0.56955114
105MP0003828_pulmonary_edema0.56804908
106MP0000249_abnormal_blood_vessel0.56494166
107MP0008873_increased_physiological_sensi0.56356207
108MP0003795_abnormal_bone_structure0.55359227
109MP0005164_abnormal_response_to0.54980750
110MP0005319_abnormal_enzyme/_coenzyme0.53976364
111MP0004381_abnormal_hair_follicle0.53464989
112MP0003786_premature_aging0.52166408
113MP0005165_increased_susceptibility_to0.51947452
114MP0000350_abnormal_cell_proliferation0.51116148
115MP0005167_abnormal_blood-brain_barrier0.50222274
116MP0001764_abnormal_homeostasis0.50189363
117MP0000477_abnormal_intestine_morphology0.49680942
118MP0009765_abnormal_xenobiotic_induced0.49645227
119MP0008874_decreased_physiological_sensi0.48320185
120MP0008872_abnormal_physiological_respon0.47336189
121MP0002136_abnormal_kidney_physiology0.46195080
122MP0009643_abnormal_urine_homeostasis0.45756678
123MP0001765_abnormal_ion_homeostasis0.44743651

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.68031879
2Eczematoid dermatitis (HP:0000976)5.14793651
3Recurrent bacterial skin infections (HP:0005406)4.92584629
4Elevated erythrocyte sedimentation rate (HP:0003565)4.87047385
5Thrombocytosis (HP:0001894)4.52455147
6Myositis (HP:0100614)4.52032694
7IgM deficiency (HP:0002850)4.35057411
8Recurrent fungal infections (HP:0002841)3.99654439
9Recurrent viral infections (HP:0004429)3.86979727
10Chronic otitis media (HP:0000389)3.86689168
11Obstructive lung disease (HP:0006536)3.81727986
12Chronic obstructive pulmonary disease (HP:0006510)3.81727986
13Meningitis (HP:0001287)3.71046667
14Recurrent bronchitis (HP:0002837)3.63987495
15Mediastinal lymphadenopathy (HP:0100721)3.63512562
16Petechiae (HP:0000967)3.58248378
17Recurrent gram-negative bacterial infections (HP:0005420)3.56874194
18Recurrent skin infections (HP:0001581)3.56085584
19Abnormality of T cells (HP:0002843)3.46758518
20Abnormality of T cell physiology (HP:0011840)3.40048706
21Cellulitis (HP:0100658)3.39297035
22Panhypogammaglobulinemia (HP:0003139)3.36326708
23Abnormal delayed hypersensitivity skin test (HP:0002963)3.34473939
24Recurrent cutaneous fungal infections (HP:0011370)3.31740125
25Chronic mucocutaneous candidiasis (HP:0002728)3.31740125
26Abnormality of macrophages (HP:0004311)3.27086242
27T lymphocytopenia (HP:0005403)3.26180630
28Abnormality of T cell number (HP:0011839)3.23640264
29Agammaglobulinemia (HP:0004432)3.17998174
30IgG deficiency (HP:0004315)3.10237876
31B lymphocytopenia (HP:0010976)3.09566687
32Abnormality of B cell number (HP:0010975)3.09566687
33Gastrointestinal infarctions (HP:0005244)3.09253593
34Orchitis (HP:0100796)3.07501077
35Aplastic anemia (HP:0001915)3.02666831
36Lymphopenia (HP:0001888)3.00551172
37Vasculitis (HP:0002633)3.00407624
38Abnormality of cells of the lymphoid lineage (HP:0012140)2.94561595
39Stomatitis (HP:0010280)2.89793256
40Retrobulbar optic neuritis (HP:0100654)2.89589768
41Optic neuritis (HP:0100653)2.89589768
42Severe combined immunodeficiency (HP:0004430)2.87725991
43Thyroiditis (HP:0100646)2.82408833
44Leukocytosis (HP:0001974)2.82386755
45Eosinophilia (HP:0001880)2.81544254
46Abnormality of the prostate (HP:0008775)2.80226748
47Granulocytopenia (HP:0001913)2.76072590
48Combined immunodeficiency (HP:0005387)2.73783923
49Autoimmune thrombocytopenia (HP:0001973)2.73162721
50Abnormality of eosinophils (HP:0001879)2.70090735
51Encephalitis (HP:0002383)2.69435769
52Spontaneous hematomas (HP:0007420)2.67109700
53Purpura (HP:0000979)2.65702748
54Prolonged bleeding time (HP:0003010)2.61752385
55Periodontitis (HP:0000704)2.61403293
56Gingivitis (HP:0000230)2.60133646
57Epistaxis (HP:0000421)2.59154155
58Reticulocytopenia (HP:0001896)2.55410711
59Hypergammaglobulinemia (HP:0010702)2.54879553
60Nasal polyposis (HP:0100582)2.51800756
61Pustule (HP:0200039)2.49869952
62Reduced antithrombin III activity (HP:0001976)2.47960095
63Inflammation of the large intestine (HP:0002037)2.47185767
64Recurrent sinusitis (HP:0011108)2.44155781
65Vacuolated lymphocytes (HP:0001922)2.44112245
66Abnormality of the pleura (HP:0002103)2.43919573
67Keratoconjunctivitis sicca (HP:0001097)2.43760764
68Gastrointestinal inflammation (HP:0004386)2.43012495
69Lymphoma (HP:0002665)2.42880665
70Pulmonary infiltrates (HP:0002113)2.42878158
71Pulmonary embolism (HP:0002204)2.41785409
72Hemoptysis (HP:0002105)2.40104376
73Recurrent pneumonia (HP:0006532)2.39498595
74Acute hepatic failure (HP:0006554)2.38035833
75Chest pain (HP:0100749)2.34350589
76Osteomyelitis (HP:0002754)2.33978281
77Recurrent lower respiratory tract infections (HP:0002783)2.31968327
78Urticaria (HP:0001025)2.29311112
79Gastrointestinal stroma tumor (HP:0100723)2.28374875
80Gangrene (HP:0100758)2.27973532
81Abnormality of the nasal mucosa (HP:0000433)2.25082003
82Chronic diarrhea (HP:0002028)2.24583124
83Sepsis (HP:0100806)2.23088937
84Abnormal number of erythroid precursors (HP:0012131)2.23037638
85Poikiloderma (HP:0001029)2.22232058
86Neutropenia (HP:0001875)2.21841160
87Keratoconjunctivitis (HP:0001096)2.21399420
88Increased IgM level (HP:0003496)2.21397150
89Verrucae (HP:0200043)2.20941202
90Papilloma (HP:0012740)2.20941202
91Joint swelling (HP:0001386)2.20597694
92IgA deficiency (HP:0002720)2.20461550
93Hepatosplenomegaly (HP:0001433)2.20382716
94Interstitial pulmonary disease (HP:0006530)2.20055248
95Autoimmune hemolytic anemia (HP:0001890)2.19939543
96Arterial thrombosis (HP:0004420)2.19128640
97Type I transferrin isoform profile (HP:0003642)2.17766849
98Skin ulcer (HP:0200042)2.16817401
99Hypoproteinemia (HP:0003075)2.16392207
100Hypochromic anemia (HP:0001931)2.16080742
101Abnormality of cells of the erythroid lineage (HP:0012130)2.14426901
102Increased neuronal autofluorescent lipopigment (HP:0002074)2.12778510
103Increased serum ferritin (HP:0003281)2.12755806
104Increased cerebral lipofuscin (HP:0011813)2.12313074
105Anorexia (HP:0002039)2.12213340
106Hypoplasia of the thymus (HP:0000778)2.11944335
107Absent rod-and cone-mediated responses on ERG (HP:0007688)2.08507885
108Abnormality of iron homeostasis (HP:0011031)2.08104398
109Episodic fever (HP:0001954)2.06748844
110Abnormality of the fingertips (HP:0001211)2.06558828
111Abnormal platelet volume (HP:0011876)2.05193452
112Abnormal platelet function (HP:0011869)2.03347583
113Impaired platelet aggregation (HP:0003540)2.03347583
114Gingival bleeding (HP:0000225)2.03005804
115Prostate neoplasm (HP:0100787)2.02072013
116Increased IgE level (HP:0003212)2.01451921
117Pulmonary fibrosis (HP:0002206)2.01107736
118Skin rash (HP:0000988)2.00161366
119Abnormality of the heme biosynthetic pathway (HP:0010472)2.00013451
120Amaurosis fugax (HP:0100576)1.99658135
121Basal ganglia calcification (HP:0002135)1.97760551
122Colitis (HP:0002583)1.96937660

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.39740442
2TXK3.37796499
3IRAK43.17076829
4KIT2.71366956
5BLK2.63681448
6BTK2.52747700
7TEC2.51874978
8ZAP702.40497397
9JAK32.08542333
10TBK11.96893057
11TYK21.96637023
12IKBKE1.95115433
13SYK1.93762135
14MAP3K141.87428090
15STK101.83055951
16TESK21.79961854
17NME21.78545347
18FLT31.77038758
19ITK1.74917167
20KDR1.69209848
21MAP3K121.67928148
22CSF1R1.67015448
23CLK11.60767548
24PIM21.59633414
25BCKDK1.51076506
26MAP2K31.40820627
27TAOK31.38897545
28LCK1.37158274
29CDC71.36646572
30ERN11.36237195
31STK161.35260002
32GRK61.35190789
33BMPR21.34651117
34WEE11.34614253
35RIPK41.34541771
36FES1.32713044
37LYN1.30737755
38ACVR1B1.28136523
39EEF2K1.25948045
40HCK1.24717041
41CSK1.23858769
42MAP3K131.23779347
43LRRK21.22645227
44VRK21.21731365
45EIF2AK11.18944832
46IKBKB1.17102692
47PIM11.12731716
48RPS6KA41.11980083
49EIF2AK31.11770530
50BRSK21.06949150
51JAK11.02286155
52NLK1.00612665
53BUB11.00397395
54IRAK30.92585430
55TGFBR10.92208290
56PRPF4B0.87013170
57GRK70.86947016
58STK40.86469162
59NUAK10.85004121
60TESK10.82556435
61FGR0.82027360
62TRPM70.81059156
63TNK20.79502005
64PKN20.78818450
65VRK10.76978408
66NEK20.76093186
67ATR0.74292062
68TGFBR20.74018687
69MAP3K30.69042092
70MARK30.65811851
71MATK0.65038353
72MST40.64039119
73RPS6KA60.63980005
74MAP2K60.63137831
75MAP3K100.62627548
76TLK10.60988622
77CDK40.60663717
78RPS6KB20.60528879
79FYN0.60029232
80PDK10.59825598
81FGFR30.58564959
82MAP3K10.58032065
83FGFR40.55097355
84RPS6KC10.54319483
85RPS6KL10.54319483
86PAK40.54135663
87MAPKAPK30.53649351
88NEK90.53630920
89EPHB10.53523350
90CDK70.53245074
91CDK190.53012261
92CHUK0.52951637
93SIK30.52651792
94MAPK40.52104901
95TAOK20.51689088
96MAP3K80.49827948
97CDK80.48313229
98MAP3K110.47208317
99PIK3CG0.46789958
100MAPK110.46623955
101MAPK120.46515143
102ADRBK20.45859945
103JAK20.45809441
104BRSK10.45543281
105PRKCD0.45454653
106MAP3K50.44958620
107PRKCQ0.44841062
108PASK0.44117138
109SCYL20.43651742
110CAMKK10.43413108
111MAPKAPK20.42837525
112DAPK10.42315578
113MYLK0.42081675
114CCNB10.41338687
115ZAK0.40615458
116EIF2AK20.39591541
117CAMKK20.38764794
118ILK0.38227291
119GRK50.38175157
120SRPK10.38159934
121HIPK20.37273139
122ABL10.36759840
123MAP4K20.36591388
124PRKG20.36126607
125TAOK10.34822328
126IGF1R0.34271185
127PTK2B0.33573823
128IRAK10.32966015
129SIK20.32103171
130MAP2K20.31928329
131RPS6KA50.31038529
132MAPK70.27521366
133MAPK30.24861336
134ADRBK10.19713797
135SMG10.19240372

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.63843155
2DNA replication_Homo sapiens_hsa030303.22716984
3Leishmaniasis_Homo sapiens_hsa051402.60146960
4Antigen processing and presentation_Homo sapiens_hsa046122.30262647
5Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.25372922
6Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.24545161
7Mismatch repair_Homo sapiens_hsa034302.23866209
8Ribosome_Homo sapiens_hsa030102.20182777
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.19121123
10Measles_Homo sapiens_hsa051622.09596269
11Base excision repair_Homo sapiens_hsa034102.06622822
12NF-kappa B signaling pathway_Homo sapiens_hsa040642.02483773
13Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.02096235
14Graft-versus-host disease_Homo sapiens_hsa053322.00852274
15Allograft rejection_Homo sapiens_hsa053301.92057298
16B cell receptor signaling pathway_Homo sapiens_hsa046621.87751930
17Hematopoietic cell lineage_Homo sapiens_hsa046401.86826621
18Non-homologous end-joining_Homo sapiens_hsa034501.72790178
19RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.71709281
20Osteoclast differentiation_Homo sapiens_hsa043801.71503614
21Homologous recombination_Homo sapiens_hsa034401.69808684
22Herpes simplex infection_Homo sapiens_hsa051681.67364425
23Proteasome_Homo sapiens_hsa030501.52333850
24Toll-like receptor signaling pathway_Homo sapiens_hsa046201.48484378
25Legionellosis_Homo sapiens_hsa051341.48006118
26Nucleotide excision repair_Homo sapiens_hsa034201.47753434
27T cell receptor signaling pathway_Homo sapiens_hsa046601.47359527
28Shigellosis_Homo sapiens_hsa051311.38119227
29Asthma_Homo sapiens_hsa053101.35102273
30Other glycan degradation_Homo sapiens_hsa005111.34000609
31Pertussis_Homo sapiens_hsa051331.33752228
32Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.30682793
33Jak-STAT signaling pathway_Homo sapiens_hsa046301.29805988
34Spliceosome_Homo sapiens_hsa030401.29280561
35NOD-like receptor signaling pathway_Homo sapiens_hsa046211.25468044
36Tuberculosis_Homo sapiens_hsa051521.22208904
37Influenza A_Homo sapiens_hsa051641.19334030
38Pyrimidine metabolism_Homo sapiens_hsa002401.18955434
39Malaria_Homo sapiens_hsa051441.18335638
40Leukocyte transendothelial migration_Homo sapiens_hsa046701.18127259
41Viral myocarditis_Homo sapiens_hsa054161.18122739
42Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.16882850
43Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.16587950
44Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.15410500
45Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.14055206
46Staphylococcus aureus infection_Homo sapiens_hsa051501.14029372
47Caffeine metabolism_Homo sapiens_hsa002321.12733904
48Hepatitis B_Homo sapiens_hsa051611.12173890
49Apoptosis_Homo sapiens_hsa042101.10717582
50Toxoplasmosis_Homo sapiens_hsa051451.09155936
51Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.07157446
52Cell cycle_Homo sapiens_hsa041101.05575078
53Salmonella infection_Homo sapiens_hsa051320.99977170
54RNA polymerase_Homo sapiens_hsa030200.98541669
55Chemokine signaling pathway_Homo sapiens_hsa040620.98002445
56Fanconi anemia pathway_Homo sapiens_hsa034600.97423360
57Pentose phosphate pathway_Homo sapiens_hsa000300.96902928
58p53 signaling pathway_Homo sapiens_hsa041150.96376425
59Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.96287484
60Acute myeloid leukemia_Homo sapiens_hsa052210.95805044
61Epstein-Barr virus infection_Homo sapiens_hsa051690.93440063
62Platelet activation_Homo sapiens_hsa046110.93042868
63Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.92323161
64Transcriptional misregulation in cancer_Homo sapiens_hsa052020.90556431
65Glycosaminoglycan degradation_Homo sapiens_hsa005310.89316669
66Autoimmune thyroid disease_Homo sapiens_hsa053200.89254496
67Protein export_Homo sapiens_hsa030600.86675526
68TNF signaling pathway_Homo sapiens_hsa046680.83413176
69RNA degradation_Homo sapiens_hsa030180.82991658
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.74379891
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.74363393
72Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.72981996
73Viral carcinogenesis_Homo sapiens_hsa052030.72083746
74Type I diabetes mellitus_Homo sapiens_hsa049400.71585005
75N-Glycan biosynthesis_Homo sapiens_hsa005100.70898873
76HTLV-I infection_Homo sapiens_hsa051660.68499620
77RNA transport_Homo sapiens_hsa030130.66183297
78Pancreatic cancer_Homo sapiens_hsa052120.65888085
79Lysosome_Homo sapiens_hsa041420.64885452
80Chronic myeloid leukemia_Homo sapiens_hsa052200.59623466
81Phagosome_Homo sapiens_hsa041450.58509284
82One carbon pool by folate_Homo sapiens_hsa006700.57971484
83Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.57256909
84Hepatitis C_Homo sapiens_hsa051600.56596635
85African trypanosomiasis_Homo sapiens_hsa051430.54139520
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.53465638
87Rheumatoid arthritis_Homo sapiens_hsa053230.51290075
88Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.50955170
89Basal transcription factors_Homo sapiens_hsa030220.50888546
90Systemic lupus erythematosus_Homo sapiens_hsa053220.50335839
91Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.50084046
92Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48551903
93Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.47538992
94Arachidonic acid metabolism_Homo sapiens_hsa005900.46623681
95Regulation of autophagy_Homo sapiens_hsa041400.45937639
96Purine metabolism_Homo sapiens_hsa002300.45244367
97AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.41954373
98Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.40312280
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39861861
100Non-small cell lung cancer_Homo sapiens_hsa052230.38418454
101Endocytosis_Homo sapiens_hsa041440.36477207
102Small cell lung cancer_Homo sapiens_hsa052220.36418380
103Galactose metabolism_Homo sapiens_hsa000520.34845521
104Colorectal cancer_Homo sapiens_hsa052100.34451122
105alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.32905114
106Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.26266623
107Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.24565334
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.22662216
109VEGF signaling pathway_Homo sapiens_hsa043700.22005404
110Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.21914567
111Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.21754426
112Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.20809657
113Glycerophospholipid metabolism_Homo sapiens_hsa005640.20149637
114Sphingolipid signaling pathway_Homo sapiens_hsa040710.19357003
115Parkinsons disease_Homo sapiens_hsa050120.17471190
116Linoleic acid metabolism_Homo sapiens_hsa005910.16739175
117Carbohydrate digestion and absorption_Homo sapiens_hsa049730.14449874
118Drug metabolism - other enzymes_Homo sapiens_hsa009830.13370843
119Peroxisome_Homo sapiens_hsa041460.12871436
120Oxidative phosphorylation_Homo sapiens_hsa001900.12111066
121Collecting duct acid secretion_Homo sapiens_hsa049660.11790594
122Adipocytokine signaling pathway_Homo sapiens_hsa049200.11697507
123Olfactory transduction_Homo sapiens_hsa047400.09637202
124Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.08123583
125Phototransduction_Homo sapiens_hsa047440.07525308
126Prolactin signaling pathway_Homo sapiens_hsa049170.05576312
127Regulation of actin cytoskeleton_Homo sapiens_hsa048100.04197122
128Nitrogen metabolism_Homo sapiens_hsa009100.03671557
129MAPK signaling pathway_Homo sapiens_hsa040100.03175490

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