ARHGEF17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)4.70864624
2locomotory exploration behavior (GO:0035641)4.62449938
3regulation of short-term neuronal synaptic plasticity (GO:0048172)4.50212686
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.30328541
5synaptic vesicle docking involved in exocytosis (GO:0016081)4.20055570
6cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.83109304
7vocalization behavior (GO:0071625)3.74223888
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.73814833
9cell communication by electrical coupling (GO:0010644)3.67971099
10layer formation in cerebral cortex (GO:0021819)3.67737723
11planar cell polarity pathway involved in neural tube closure (GO:0090179)3.59268492
12plasma membrane repair (GO:0001778)3.57289457
13regulation of synapse structural plasticity (GO:0051823)3.56661927
14glutamate secretion (GO:0014047)3.51030078
15cell migration involved in heart development (GO:0060973)3.50899667
16sodium ion export (GO:0071436)3.48922733
17regulation of synaptic vesicle exocytosis (GO:2000300)3.47036874
18protein heterotrimerization (GO:0070208)3.46807257
19synaptic vesicle exocytosis (GO:0016079)3.45868121
20cytoskeletal anchoring at plasma membrane (GO:0007016)3.44450558
21activation of protein kinase A activity (GO:0034199)3.42841183
22regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.40269376
23collagen fibril organization (GO:0030199)3.31710280
24atrioventricular valve morphogenesis (GO:0003181)3.31642997
25regulation of glutamate receptor signaling pathway (GO:1900449)3.29902934
26exploration behavior (GO:0035640)3.29497205
27basement membrane organization (GO:0071711)3.29244380
28regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.27911609
29regulation of neuronal synaptic plasticity (GO:0048168)3.27765691
30adherens junction assembly (GO:0034333)3.27197794
31dendritic spine morphogenesis (GO:0060997)3.26154478
32membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.24411036
33vascular endothelial growth factor signaling pathway (GO:0038084)3.19429742
34cellular potassium ion homeostasis (GO:0030007)3.15971167
35regulation of long-term neuronal synaptic plasticity (GO:0048169)3.11982209
36cell-substrate adherens junction assembly (GO:0007045)3.10383831
37focal adhesion assembly (GO:0048041)3.10383831
38neuromuscular process controlling balance (GO:0050885)3.06576899
39cell-substrate junction assembly (GO:0007044)3.06087894
40regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.04316815
41regulation of synaptic vesicle transport (GO:1902803)3.02183615
42neurotransmitter secretion (GO:0007269)3.01492040
43semaphorin-plexin signaling pathway (GO:0071526)2.99114163
44kidney mesenchyme development (GO:0072074)2.98519117
45establishment of nucleus localization (GO:0040023)2.97680935
46cerebellar Purkinje cell layer development (GO:0021680)2.90092913
47neuronal action potential propagation (GO:0019227)2.89350382
48endodermal cell differentiation (GO:0035987)2.87996094
49bone trabecula formation (GO:0060346)2.87647229
50cell communication involved in cardiac conduction (GO:0086065)2.85497163
51cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.83962364
52metanephric mesenchyme development (GO:0072075)2.83711234
53extracellular matrix assembly (GO:0085029)2.83440617
54negative regulation of cytosolic calcium ion concentration (GO:0051481)2.81932408
55protein localization to synapse (GO:0035418)2.81863571
56negative regulation of catenin import into nucleus (GO:0035414)2.79881546
57regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.78288505
58skin morphogenesis (GO:0043589)2.73150502
59proline transport (GO:0015824)2.72563359
60positive regulation of synapse maturation (GO:0090129)2.72555413
61potassium ion import (GO:0010107)2.70504935
62endothelial cell morphogenesis (GO:0001886)2.69679732
63stress fiber assembly (GO:0043149)2.69464581
64ionotropic glutamate receptor signaling pathway (GO:0035235)2.68707638
65innervation (GO:0060384)2.68595706
66chondrocyte proliferation (GO:0035988)2.68223793
67axonal fasciculation (GO:0007413)2.67976655
68vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.66025114
69negative regulation of chondrocyte differentiation (GO:0032331)2.65282506
70regulation of dendritic spine morphogenesis (GO:0061001)2.65227518
71dendritic spine organization (GO:0097061)2.64521573
72regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.64047695
73peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.63822925
74Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.63247998
75regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.63091303
76endothelial cell chemotaxis (GO:0035767)2.63077970
77long-term memory (GO:0007616)2.62568267
78regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.62481871
79endocardial cushion development (GO:0003197)2.61625412
80dendrite morphogenesis (GO:0048813)2.60974983
81glomerular basement membrane development (GO:0032836)2.60493056
82dermatan sulfate metabolic process (GO:0030205)2.59748083
83peripheral nervous system axon ensheathment (GO:0032292)2.59572213
84myelination in peripheral nervous system (GO:0022011)2.59572213
85regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.58613818
86positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.58164344
87neuronal ion channel clustering (GO:0045161)2.56675073
88neuron recognition (GO:0008038)2.56212550
89negative regulation of fatty acid transport (GO:2000192)2.54970801
90cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.54895969
91regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.53707339
92retina vasculature morphogenesis in camera-type eye (GO:0061299)2.52064426
93regulation of synaptic plasticity (GO:0048167)2.51999962
94extracellular fibril organization (GO:0043206)2.51390585
95vesicle transport along microtubule (GO:0047496)2.51283201
96collagen metabolic process (GO:0032963)2.51207406
97membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.51057171
98regulation of ARF protein signal transduction (GO:0032012)2.50183926
99auditory behavior (GO:0031223)2.49484676
100cell volume homeostasis (GO:0006884)2.49445513
101camera-type eye morphogenesis (GO:0048593)2.49136476
102cellular sodium ion homeostasis (GO:0006883)2.48973367
103G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.48878803
104regulation of axon extension involved in axon guidance (GO:0048841)2.48358690
105regulation of establishment of planar polarity (GO:0090175)2.48336004
106regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.47784858
107membrane depolarization during action potential (GO:0086010)2.47627566
108synaptic transmission, glutamatergic (GO:0035249)2.47592276
109protein retention in ER lumen (GO:0006621)2.46820454
110regulation of membrane repolarization (GO:0060306)2.46089456
111cardiac myofibril assembly (GO:0055003)2.46006731
112neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.45897569
113epithelial cell-cell adhesion (GO:0090136)2.44603815
114paraxial mesoderm development (GO:0048339)2.43736054
115membrane repolarization (GO:0086009)2.43194591
116positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.42358905
117regulation of excitatory postsynaptic membrane potential (GO:0060079)2.42286864
118positive regulation of fibroblast migration (GO:0010763)2.41555167
119potassium ion homeostasis (GO:0055075)2.41505256
120cerebellar Purkinje cell differentiation (GO:0021702)2.40481928
121dermatan sulfate biosynthetic process (GO:0030208)2.39512936
122collagen catabolic process (GO:0030574)2.38704349
123negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.38564638
124positive regulation of synaptic transmission, GABAergic (GO:0032230)2.38100068
125neuromuscular junction development (GO:0007528)2.36264877
126positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.36236670
127neuromuscular process controlling posture (GO:0050884)2.35721834
128neurotransmitter-gated ion channel clustering (GO:0072578)2.35634131
129multicellular organismal macromolecule metabolic process (GO:0044259)2.35401353
130regulation of postsynaptic membrane potential (GO:0060078)2.34642592
131regulation of calcium ion transmembrane transporter activity (GO:1901019)2.34001613
132regulation of calcium ion transmembrane transport (GO:1903169)2.34001613
133regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.33811336
134cell proliferation involved in metanephros development (GO:0072203)2.33754863
135chemosensory behavior (GO:0007635)2.33469250
136dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.33429313
137positive regulation of membrane potential (GO:0045838)2.33365629
138actin filament depolymerization (GO:0030042)2.33160538
139positive regulation of blood vessel endothelial cell migration (GO:0043536)2.33028084
140axon extension (GO:0048675)2.32525099
141regulation of axon guidance (GO:1902667)2.32385046
142negative regulation of potassium ion transmembrane transport (GO:1901380)2.32186232
143axon extension involved in axon guidance (GO:0048846)2.31730181
144neuron projection extension involved in neuron projection guidance (GO:1902284)2.31730181
145venous blood vessel morphogenesis (GO:0048845)2.31208262
146suckling behavior (GO:0001967)2.31090084
147insulin-like growth factor receptor signaling pathway (GO:0048009)2.31011819
148cochlea morphogenesis (GO:0090103)2.30944865
149hemidesmosome assembly (GO:0031581)2.30850712
150mating behavior (GO:0007617)2.30631514
151positive regulation of potassium ion transport (GO:0043268)2.30389174
152neuromuscular process (GO:0050905)2.29833403
153maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.29645174
154regulation of clathrin-mediated endocytosis (GO:2000369)2.29320535
155protein targeting to plasma membrane (GO:0072661)2.29125708
156detection of calcium ion (GO:0005513)2.28718949
157glutamate receptor signaling pathway (GO:0007215)2.28680453
158positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.28414207
159prepulse inhibition (GO:0060134)2.28103968
160cell-cell junction maintenance (GO:0045217)2.27045643
161regulation of cardioblast differentiation (GO:0051890)2.26853444
162extracellular matrix disassembly (GO:0022617)2.26808494
163metanephric nephron epithelium development (GO:0072243)2.25809681
164barbed-end actin filament capping (GO:0051016)2.24967890
165convergent extension (GO:0060026)2.24883950
166endocardial cushion morphogenesis (GO:0003203)2.24642103
167non-canonical Wnt signaling pathway (GO:0035567)2.24025991
168positive regulation of osteoblast proliferation (GO:0033690)2.23244137
169renal filtration (GO:0097205)2.23125412
170multicellular organismal metabolic process (GO:0044236)2.20549447
171negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.20018716
172sequestering of extracellular ligand from receptor (GO:0035581)2.19701175
173branching involved in salivary gland morphogenesis (GO:0060445)2.19218763
174positive regulation of receptor recycling (GO:0001921)2.18434927
175cell migration involved in sprouting angiogenesis (GO:0002042)2.18429182
176mesenchyme morphogenesis (GO:0072132)2.18383564
177cerebellar granule cell differentiation (GO:0021707)2.17655709
178substrate adhesion-dependent cell spreading (GO:0034446)2.16594028
179metanephric nephron tubule development (GO:0072234)2.15902696

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.47850349
2THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.81075523
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.79695103
4* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.64858102
5* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.64858102
6PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.64252338
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.62684687
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.57815767
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.45170946
10DROSHA_22980978_ChIP-Seq_HELA_Human2.41963412
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.34289644
12* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.33596013
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.31390145
14RARB_27405468_Chip-Seq_BRAIN_Mouse2.26085754
15EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.22259623
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.22242066
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.21841375
18* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.20566289
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.17784558
20RNF2_27304074_Chip-Seq_ESCs_Mouse2.08963793
21* EZH2_27294783_Chip-Seq_ESCs_Mouse2.01033476
22WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.97092108
23* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.96963004
24TRIM28_21343339_ChIP-Seq_HEK293_Human1.89639072
25GBX2_23144817_ChIP-Seq_PC3_Human1.89539200
26* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.88280391
27CLOCK_20551151_ChIP-Seq_293T_Human1.86692775
28MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.80214515
29ZFP281_18757296_ChIP-ChIP_E14_Mouse1.78845641
30* ELK3_25401928_ChIP-Seq_HUVEC_Human1.77383569
31TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.72832344
32KDM2B_26808549_Chip-Seq_K562_Human1.70818262
33IKZF1_21737484_ChIP-ChIP_HCT116_Human1.70716215
34ERG_21242973_ChIP-ChIP_JURKAT_Human1.70145528
35TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.70134817
36REST_21632747_ChIP-Seq_MESCs_Mouse1.68057848
37* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.66969975
38ESR1_21235772_ChIP-Seq_MCF-7_Human1.62121622
39EP300_21415370_ChIP-Seq_HL-1_Mouse1.60135771
40RACK7_27058665_Chip-Seq_MCF-7_Human1.59522877
41* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.57310570
42* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.56148136
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.56030916
44CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.47974919
45EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.47824622
46* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.46109777
47TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.45649253
48UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.45057392
49REST_18959480_ChIP-ChIP_MESCs_Mouse1.44165313
50ZFP281_27345836_Chip-Seq_ESCs_Mouse1.41037271
51* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.40413636
52GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.39698311
53NFIB_24661679_ChIP-Seq_LUNG_Mouse1.38936671
54ZNF217_24962896_ChIP-Seq_MCF-7_Human1.38474619
55SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.38368128
56* RING1B_27294783_Chip-Seq_ESCs_Mouse1.37581008
57STAT6_21828071_ChIP-Seq_BEAS2B_Human1.36712244
58SOX9_24532713_ChIP-Seq_HFSC_Mouse1.34732727
59ESR2_21235772_ChIP-Seq_MCF-7_Human1.33746209
60PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.31980281
61RARG_19884340_ChIP-ChIP_MEFs_Mouse1.30334210
62* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.29865480
63DNAJC2_21179169_ChIP-ChIP_NT2_Human1.29642130
64NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.29263171
65ZNF274_21170338_ChIP-Seq_K562_Hela1.28599421
66RING1B_27294783_Chip-Seq_NPCs_Mouse1.26612983
67CDX2_19796622_ChIP-Seq_MESCs_Mouse1.24865806
68TP53_22127205_ChIP-Seq_IMR90_Human1.23640398
69AR_19668381_ChIP-Seq_PC3_Human1.22191537
70NR3C1_23031785_ChIP-Seq_PC12_Mouse1.21881391
71ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.21711240
72RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.21620404
73AR_21572438_ChIP-Seq_LNCaP_Human1.21175009
74KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.20340296
75ZNF263_19887448_ChIP-Seq_K562_Human1.19739807
76NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.19673121
77ESR1_20079471_ChIP-ChIP_T-47D_Human1.19401536
78TP53_20018659_ChIP-ChIP_R1E_Mouse1.18071223
79SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.17102130
80* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.15740208
81AHR_22903824_ChIP-Seq_MCF-7_Human1.13794048
82* SMC3_22415368_ChIP-Seq_MEFs_Mouse1.13245927
83SOX2_21211035_ChIP-Seq_LN229_Gbm1.12878323
84ISL1_27105846_Chip-Seq_CPCs_Mouse1.08842268
85SMAD4_21799915_ChIP-Seq_A2780_Human1.08666723
86ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.07187382
87CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.06582816
88SMAD3_21741376_ChIP-Seq_HESCs_Human1.05505658
89PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.05207509
90ARNT_22903824_ChIP-Seq_MCF-7_Human1.04832165
91GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.03470239
92KDM2B_26808549_Chip-Seq_DND41_Human1.03287666
93SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.03167912
94SMC4_20622854_ChIP-Seq_HELA_Human1.02908235
95LXR_22292898_ChIP-Seq_THP-1_Human1.02401455
96YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01933547
97GATA2_21666600_ChIP-Seq_HMVEC_Human1.01846871
98TP53_16413492_ChIP-PET_HCT116_Human1.00969511
99SMAD4_21741376_ChIP-Seq_HESCs_Human1.00891501
100* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.00697817
101PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.00639716
102TCF7_22412390_ChIP-Seq_EML_Mouse1.00208305
103KDM2B_26808549_Chip-Seq_JURKAT_Human0.99877950
104RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.99374481
105* CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.98675215
106* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.98087569
107BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97953233
108NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.97490912
109TET1_21490601_ChIP-Seq_MESCs_Mouse0.97144699
110* CTCF_27219007_Chip-Seq_Bcells_Human0.95410852
111TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.95105111
112UBF1/2_26484160_Chip-Seq_HMECs_Human0.94670983
113* RUNX1_27514584_Chip-Seq_MCF-7_Human0.94616828
114WT1_19549856_ChIP-ChIP_CCG9911_Human0.94434231
115SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.94373733
116CTBP2_25329375_ChIP-Seq_LNCAP_Human0.94301390
117SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.94268081
118ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.93118362
119ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.93029194
120PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92734518
121SMAD_19615063_ChIP-ChIP_OVARY_Human0.92044229
122CTNNB1_20460455_ChIP-Seq_HCT116_Human0.91282764
123RXR_22108803_ChIP-Seq_LS180_Human0.91060415
124SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90507676
125* TP53_23651856_ChIP-Seq_MEFs_Mouse0.87908743
126* CREB1_26743006_Chip-Seq_LNCaP_Human0.86847230
127PIAS1_25552417_ChIP-Seq_VCAP_Human0.86805193
128* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.86314763
129TBX20_22080862_ChIP-Seq_HEART_Mouse0.86006592
130TBX20_22328084_ChIP-Seq_HEART_Mouse0.86006592
131SMAD3_21741376_ChIP-Seq_ESCs_Human0.85702056
132STAT3_23295773_ChIP-Seq_U87_Human0.85089591
133TP63_17297297_ChIP-ChIP_HaCaT_Human0.84959272

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.13114543
2MP0003283_abnormal_digestive_organ2.86289672
3MP0003635_abnormal_synaptic_transmissio2.85992892
4MP0009780_abnormal_chondrocyte_physiolo2.77904772
5MP0005623_abnormal_meninges_morphology2.71489165
6MP0004270_analgesia2.60331928
7MP0000751_myopathy2.44877388
8MP0005257_abnormal_intraocular_pressure2.35992299
9MP0003566_abnormal_cell_adhesion2.23967529
10MP0009384_cardiac_valve_regurgitation2.23471653
11MP0002909_abnormal_adrenal_gland2.19486289
12MP0002063_abnormal_learning/memory/cond2.17216060
13MP0003880_abnormal_central_pattern2.12220634
14MP0000013_abnormal_adipose_tissue2.04683456
15MP0004858_abnormal_nervous_system2.02652649
16MP0009745_abnormal_behavioral_response2.00643419
17MP0003122_maternal_imprinting1.97216241
18MP0000767_abnormal_smooth_muscle1.89802199
19MP0002822_catalepsy1.86941429
20MP0004272_abnormal_basement_membrane1.85480009
21MP0002064_seizures1.82983034
22MP0005409_darkened_coat_color1.75678821
23MP0008438_abnormal_cutaneous_collagen1.74754866
24MP0004145_abnormal_muscle_electrophysio1.69117870
25MP0002837_dystrophic_cardiac_calcinosis1.68576351
26MP0004084_abnormal_cardiac_muscle1.68411209
27MP0003705_abnormal_hypodermis_morpholog1.64946244
28MP0009046_muscle_twitch1.63419391
29MP0002572_abnormal_emotion/affect_behav1.61710860
30MP0004233_abnormal_muscle_weight1.60458636
31MP0005508_abnormal_skeleton_morphology1.58372098
32MP0001348_abnormal_lacrimal_gland1.55258018
33MP0001849_ear_inflammation1.52843701
34MP0002734_abnormal_mechanical_nocicepti1.51023661
35MP0005503_abnormal_tendon_morphology1.49120352
36MP0002249_abnormal_larynx_morphology1.48254112
37MP0002272_abnormal_nervous_system1.46501736
38MP0001299_abnormal_eye_distance/1.45883151
39MP0001968_abnormal_touch/_nociception1.45841053
40MP0000534_abnormal_ureter_morphology1.40831701
41MP0001486_abnormal_startle_reflex1.40231756
42MP0002295_abnormal_pulmonary_circulatio1.38911538
43MP0001879_abnormal_lymphatic_vessel1.37094461
44MP0002234_abnormal_pharynx_morphology1.33331328
45MP0005023_abnormal_wound_healing1.32389051
46MP0008961_abnormal_basal_metabolism1.32024242
47MP0005595_abnormal_vascular_smooth1.30107705
48MP0004036_abnormal_muscle_relaxation1.29579640
49MP0004811_abnormal_neuron_physiology1.29241217
50MP0008569_lethality_at_weaning1.27705077
51MP0003045_fibrosis1.27103964
52MP0005423_abnormal_somatic_nervous1.25116011
53MP0004215_abnormal_myocardial_fiber1.24236418
54MP0001501_abnormal_sleep_pattern1.23937970
55MP0000733_abnormal_muscle_development1.22711808
56MP0005275_abnormal_skin_tensile1.22298042
57MP0001958_emphysema1.20416311
58MP0003329_amyloid_beta_deposits1.20305358
59MP0003279_aneurysm1.19741374
60MP0000003_abnormal_adipose_tissue1.17696787
61MP0002060_abnormal_skin_morphology1.16909148
62MP0004085_abnormal_heartbeat1.15605914
63MP0003879_abnormal_hair_cell1.15276598
64MP0009250_abnormal_appendicular_skeleto1.14391836
65MP0001440_abnormal_grooming_behavior1.14187577
66MP0000762_abnormal_tongue_morphology1.13927966
67MP0003137_abnormal_impulse_conducting1.13800998
68MP0004087_abnormal_muscle_fiber1.12174142
69MP0002184_abnormal_innervation1.11536289
70MP0003123_paternal_imprinting1.11367087
71MP0000566_synostosis1.11127560
72MP0000955_abnormal_spinal_cord1.11073465
73MP0002733_abnormal_thermal_nociception1.10375700
74MP0000462_abnormal_digestive_system1.10269555
75MP0003385_abnormal_body_wall1.09559248
76MP0004885_abnormal_endolymph1.08130584
77MP0001542_abnormal_bone_strength1.07258558
78MP0005620_abnormal_muscle_contractility1.06137858
79MP0000747_muscle_weakness1.05296786
80MP0002108_abnormal_muscle_morphology1.04691231
81MP0010234_abnormal_vibrissa_follicle1.03507391
82MP0000749_muscle_degeneration1.03402113
83MP0005670_abnormal_white_adipose1.03242056
84MP0000778_abnormal_nervous_system1.02831364
85MP0001970_abnormal_pain_threshold1.02147353
86MP0005076_abnormal_cell_differentiation1.00511842
87MP0000537_abnormal_urethra_morphology1.00357919
88MP0005187_abnormal_penis_morphology0.99521267
89MP0003942_abnormal_urinary_system0.99195057
90MP0002557_abnormal_social/conspecific_i0.98499767
91MP0002067_abnormal_sensory_capabilities0.96863324
92MP0002896_abnormal_bone_mineralization0.96790105
93MP0010030_abnormal_orbit_morphology0.95776439
94MP0002972_abnormal_cardiac_muscle0.95049907
95MP0006138_congestive_heart_failure0.94633033
96MP0002882_abnormal_neuron_morphology0.94237070
97MP0002877_abnormal_melanocyte_morpholog0.93594577
98MP0005167_abnormal_blood-brain_barrier0.93364989
99MP0005330_cardiomyopathy0.92952970
100MP0003787_abnormal_imprinting0.92794890
101MP0001177_atelectasis0.91372359
102MP0003091_abnormal_cell_migration0.89883746
103MP0002116_abnormal_craniofacial_bone0.88773790
104MP0003950_abnormal_plasma_membrane0.88760267
105MP0005375_adipose_tissue_phenotype0.88723572
106MP0010630_abnormal_cardiac_muscle0.88417804
107MP0004484_altered_response_of0.87909833
108MP0000759_abnormal_skeletal_muscle0.87581721
109MP0002128_abnormal_blood_circulation0.87506753
110MP0010368_abnormal_lymphatic_system0.87237402
111MP0002066_abnormal_motor_capabilities/c0.87030625
112MP0003115_abnormal_respiratory_system0.86660493
113MP0004130_abnormal_muscle_cell0.86549037
114MP0002269_muscular_atrophy0.85984277
115MP0010386_abnormal_urinary_bladder0.85249123
116MP0000163_abnormal_cartilage_morphology0.85038862
117MP0003633_abnormal_nervous_system0.84642581
118MP0003634_abnormal_glial_cell0.84576666
119MP0002932_abnormal_joint_morphology0.84495267
120MP0002735_abnormal_chemical_nociception0.83015247
121MP0004924_abnormal_behavior0.82108028
122MP0005386_behavior/neurological_phenoty0.82108028
123MP0001614_abnormal_blood_vessel0.81642714
124MP0000049_abnormal_middle_ear0.81533692
125MP0002736_abnormal_nociception_after0.81211333
126MP0002089_abnormal_postnatal_growth/wei0.80906130
127MP0002152_abnormal_brain_morphology0.80357310
128MP0000428_abnormal_craniofacial_morphol0.79566448
129MP0001502_abnormal_circadian_rhythm0.79040640
130MP0002133_abnormal_respiratory_system0.78389637
131MP0005388_respiratory_system_phenotype0.78389637
132MP0005369_muscle_phenotype0.77946214
133MP0008775_abnormal_heart_ventricle0.76560195
134MP0000579_abnormal_nail_morphology0.75634515
135MP0005646_abnormal_pituitary_gland0.75617348
136MP0000569_abnormal_digit_pigmentation0.75590610
137MP0002925_abnormal_cardiovascular_devel0.75177977
138MP0009053_abnormal_anal_canal0.72392223
139MP0002115_abnormal_skeleton_extremities0.71646991
140MP0002933_joint_inflammation0.71079714
141MP0006054_spinal_hemorrhage0.70339226
142MP0003935_abnormal_craniofacial_develop0.67718364
143MP0002114_abnormal_axial_skeleton0.67638193
144MP0000432_abnormal_head_morphology0.65951837
145MP0003755_abnormal_palate_morphology0.64352143
146MP0001243_abnormal_dermal_layer0.62004267
147MP0001346_abnormal_lacrimal_gland0.61510664
148MP0000750_abnormal_muscle_regeneration0.60203796
149MP0002113_abnormal_skeleton_development0.60139730
150MP0005171_absent_coat_pigmentation0.60042420

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)3.93258093
2Focal motor seizures (HP:0011153)3.53853123
3Protrusio acetabuli (HP:0003179)3.21223760
4Obstructive sleep apnea (HP:0002870)3.13249917
5Focal seizures (HP:0007359)3.09628330
6Cervical subluxation (HP:0003308)3.06813512
7Shallow orbits (HP:0000586)3.01118199
8Soft skin (HP:0000977)3.01096080
9Neonatal short-limb short stature (HP:0008921)3.00327480
10Cerebral aneurysm (HP:0004944)2.98402742
11Visual hallucinations (HP:0002367)2.90571289
12Abnormality of dentin (HP:0010299)2.90500787
13Action tremor (HP:0002345)2.87139453
14Wormian bones (HP:0002645)2.81955850
15Broad metatarsal (HP:0001783)2.73756751
16Ulnar bowing (HP:0003031)2.62524056
17Premature rupture of membranes (HP:0001788)2.59009409
18Blue sclerae (HP:0000592)2.53375517
19Mitral regurgitation (HP:0001653)2.52635884
20Bundle branch block (HP:0011710)2.51754953
21Ventricular fibrillation (HP:0001663)2.51356825
22Sudden death (HP:0001699)2.47574159
23Increased variability in muscle fiber diameter (HP:0003557)2.41058467
24Ankle contracture (HP:0006466)2.40373926
25Bladder diverticulum (HP:0000015)2.38594944
26Broad face (HP:0000283)2.34535657
27Wide anterior fontanel (HP:0000260)2.32325443
28Biconcave vertebral bodies (HP:0004586)2.31873674
29Joint laxity (HP:0001388)2.29942631
30Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.28475567
31Aortic regurgitation (HP:0001659)2.26577352
32Bronchomalacia (HP:0002780)2.26506078
33Depression (HP:0000716)2.25945451
34Pointed chin (HP:0000307)2.22496619
35Follicular hyperkeratosis (HP:0007502)2.21334661
36Papilledema (HP:0001085)2.19778308
37Insomnia (HP:0100785)2.19504579
38Ankle clonus (HP:0011448)2.19414490
39Mildly elevated creatine phosphokinase (HP:0008180)2.18129868
40Hypoventilation (HP:0002791)2.17541448
41Atonic seizures (HP:0010819)2.13217238
42Buphthalmos (HP:0000557)2.12826016
43Abnormality of the lower motor neuron (HP:0002366)2.12709758
44Upper limb amyotrophy (HP:0009129)2.12684867
45Distal upper limb amyotrophy (HP:0007149)2.12684867
46Round ear (HP:0100830)2.12290924
47Prolonged QT interval (HP:0001657)2.11859934
48Atrophic scars (HP:0001075)2.10063928
49Type 1 muscle fiber predominance (HP:0003803)2.08363493
50Bowel diverticulosis (HP:0005222)2.08342387
51Hemiplegia (HP:0002301)2.07840814
52Renal duplication (HP:0000075)2.07778741
53Distal lower limb amyotrophy (HP:0008944)2.07622896
54Vertebral compression fractures (HP:0002953)2.06289748
55Coronal craniosynostosis (HP:0004440)2.05953630
56Hyperacusis (HP:0010780)2.05508742
57Neoplasm of the heart (HP:0100544)2.02504992
58Hypoplasia of the iris (HP:0007676)2.02164658
59Difficulty running (HP:0009046)2.01305799
60Generalized tonic-clonic seizures (HP:0002069)2.00554762
61Megalencephaly (HP:0001355)2.00469706
62Ankyloglossia (HP:0010296)2.00171966
63Aplasia involving bones of the extremities (HP:0009825)2.00012153
64Aplasia involving bones of the upper limbs (HP:0009823)2.00012153
65Aplasia of the phalanges of the hand (HP:0009802)2.00012153
66Disproportionate tall stature (HP:0001519)1.99405269
67Lower limb amyotrophy (HP:0007210)1.98368808
68Hypercortisolism (HP:0001578)1.97338824
69Overgrowth (HP:0001548)1.96955212
70Distal lower limb muscle weakness (HP:0009053)1.96434591
71Enlarged penis (HP:0000040)1.96419399
72Dilatation of the ascending aorta (HP:0005111)1.96004494
73Short nail (HP:0001799)1.95853036
74Abnormality of skeletal muscle fiber size (HP:0012084)1.95688910
75Epileptic encephalopathy (HP:0200134)1.95341441
76Absence seizures (HP:0002121)1.94973871
77Ectopia lentis (HP:0001083)1.94675833
78Annular pancreas (HP:0001734)1.94094501
79Joint stiffness (HP:0001387)1.92156774
80Turricephaly (HP:0000262)1.91849970
81Thin ribs (HP:0000883)1.91219942
82Lymphangioma (HP:0100764)1.90949517
83Rapidly progressive (HP:0003678)1.90609785
84Slender build (HP:0001533)1.90570490
85Infantile muscular hypotonia (HP:0008947)1.90140533
86Thin bony cortex (HP:0002753)1.88958203
87Difficulty climbing stairs (HP:0003551)1.88345582
88Supranuclear gaze palsy (HP:0000605)1.87581506
89Progressive cerebellar ataxia (HP:0002073)1.87060407
90Abnormality of the calf musculature (HP:0001430)1.86404607
91Macroorchidism (HP:0000053)1.86400478
92Torticollis (HP:0000473)1.86228737
93Aneurysm (HP:0002617)1.86226318
94Wrist flexion contracture (HP:0001239)1.85962510
95Resting tremor (HP:0002322)1.85882339
96Atrial fibrillation (HP:0005110)1.85688488
97Camptodactyly of toe (HP:0001836)1.84967907
98Primary atrial arrhythmia (HP:0001692)1.84878930
99Peritonitis (HP:0002586)1.84821435
100Increased connective tissue (HP:0009025)1.83641352
101Mitral valve prolapse (HP:0001634)1.83623355
102Impaired vibration sensation in the lower limbs (HP:0002166)1.82293314
103Aortic dissection (HP:0002647)1.82262390
104Spondylolisthesis (HP:0003302)1.81522610
105Mild short stature (HP:0003502)1.80435618
106Hyporeflexia of lower limbs (HP:0002600)1.80247959
107Abnormal EKG (HP:0003115)1.80231662
108Congenital glaucoma (HP:0001087)1.80169436
109Fragile skin (HP:0001030)1.80071456
110Anxiety (HP:0000739)1.80060467
111Dysmetric saccades (HP:0000641)1.79848819
112Exercise-induced myalgia (HP:0003738)1.79051135
113Dysdiadochokinesis (HP:0002075)1.75482099
114Aortic valve stenosis (HP:0001650)1.75326182
115Limited hip movement (HP:0008800)1.74881373
116Poor eye contact (HP:0000817)1.74506429
117Aortic aneurysm (HP:0004942)1.74463438
118Supraventricular arrhythmia (HP:0005115)1.74188112
119Scapular winging (HP:0003691)1.73077419
120Insidious onset (HP:0003587)1.72385557
121Termporal pattern (HP:0011008)1.72385557
122Long toe (HP:0010511)1.72226328
123Abnormality of the acetabulum (HP:0003170)1.71908155
124Osteoarthritis (HP:0002758)1.71894389
125Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.71823113
126Abnormal social behavior (HP:0012433)1.71604089
127Impaired social interactions (HP:0000735)1.71604089
128Genetic anticipation (HP:0003743)1.71291996
129Elfin facies (HP:0004428)1.70738642
130Genu recurvatum (HP:0002816)1.70508524
131Postural instability (HP:0002172)1.70474653
132Venous abnormality (HP:0002624)1.69881826
133Stridor (HP:0010307)1.69563397
134Flat cornea (HP:0007720)1.69347175
135Supraventricular tachycardia (HP:0004755)1.69166254
136Mitral stenosis (HP:0001718)1.68079255
137Striae distensae (HP:0001065)1.67850105
138Arterial tortuosity (HP:0005116)1.67511971
139Spinal rigidity (HP:0003306)1.67115691
140Vascular tortuosity (HP:0004948)1.66736226
141Syncope (HP:0001279)1.66208523
142Hyperextensible skin (HP:0000974)1.66011732
143Osteolytic defects of the hand bones (HP:0009699)1.65675144
144Osteolytic defects of the phalanges of the hand (HP:0009771)1.65675144
145Venous insufficiency (HP:0005293)1.65054891
146Hip contracture (HP:0003273)1.64709879
147Abnormal delivery (HP:0001787)1.63939426
148Coxa vara (HP:0002812)1.63743169
149Elbow flexion contracture (HP:0002987)1.63494127
150Inguinal hernia (HP:0000023)1.62845913
151Deviation of the hallux (HP:0010051)1.62455374
152Arnold-Chiari malformation (HP:0002308)1.62363769
153Protruding ear (HP:0000411)1.61122350
154Pulmonary artery stenosis (HP:0004415)1.60807341
155Natal tooth (HP:0000695)1.60699446
156Vertebral arch anomaly (HP:0008438)1.60521988
157Advanced eruption of teeth (HP:0006288)1.60225780

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.50671524
2PRKD33.40370430
3EPHA43.19028667
4MAP3K92.76817892
5TRIB32.67426387
6NTRK12.27618464
7PDGFRA2.23894082
8PAK62.20456689
9KSR22.15959394
10RIPK12.06805767
11MINK12.05614192
12DDR22.00487288
13DAPK21.93564141
14CAMKK11.91180994
15MAP3K41.91079774
16LATS21.90331603
17TTN1.88336320
18EPHA21.75591197
19STK381.64392229
20LMTK21.57620761
21PKN21.57417487
22DMPK1.51827656
23EEF2K1.49977577
24MAP3K21.49386705
25TESK11.49017168
26PAK31.46936502
27TYRO31.44970531
28MET1.36906286
29NTRK21.34721502
30FGFR41.34167260
31ERN11.32110148
32PRKCH1.30091388
33TIE11.28191014
34FER1.26175454
35KSR11.26064156
36PHKG21.23682922
37PHKG11.23682922
38RET1.23240291
39MAP3K61.20049187
40CDK51.19552784
41MARK11.19355182
42CDK121.16813400
43LIMK11.15058558
44TAOK11.13901069
45MAP2K41.13723265
46PTK2B1.10697849
47SMG11.08901213
48CDC42BPA1.07462291
49NEK91.04864068
50PTK21.04046646
51UHMK11.03798083
52EPHB21.02781760
53WNK41.02763148
54LATS11.01468378
55EPHB11.01419366
56ALK0.93953896
57BMX0.92855345
58CAMK1G0.92775207
59WNK10.90334110
60NEK10.90193868
61PAK40.89812620
62SIK20.88280117
63MAPK150.85282993
64MAP3K10.83522341
65PTK60.82328745
66MAP3K70.82184619
67ROCK10.82183532
68CAMK10.80829706
69TGFBR20.80137819
70SCYL20.77923503
71CAMK2G0.75684214
72PLK20.74818394
73DAPK10.74467657
74MAPK70.74425301
75PRKD20.74042075
76MARK20.73532794
77STK110.73248533
78PDGFRB0.72292058
79ICK0.72230763
80AKT30.72121631
81FGFR20.69776464
82SGK30.69708506
83MAP2K10.69553611
84PRKCG0.69327195
85CAMKK20.68953191
86MAP2K70.68647582
87PRKG20.68473962
88SIK10.68224628
89MST1R0.67918676
90CDK140.67866902
91CDK150.67568422
92CAMK2A0.66971206
93TRPM70.65751006
94CDK180.65359667
95PAK20.64581078
96FGFR10.63206902
97MAPK120.63087858
98RPS6KC10.62484607
99RPS6KL10.62484607
100PRKD10.61498092
101DAPK30.60435418
102PDPK10.59236024
103GRK50.58873546
104SGK4940.57684402
105SGK2230.57684402
106MYLK0.57397010
107SGK10.56543623
108CDK11A0.55351436
109PNCK0.54956002
110CAMK2B0.53122190
111CAMK2D0.52108311
112CAMK40.51413709
113ROCK20.51280471
114PRPF4B0.51051939
115RPS6KA30.50372687
116MTOR0.49185409
117RPS6KA20.48697297
118MAPKAPK30.46010878
119ARAF0.45697750
120PRKCE0.45375438
121PDK10.45047086
122MUSK0.44896508
123MOS0.44459602
124PINK10.44390886
125SGK20.43897639
126RPS6KA60.43763328
127ILK0.43300131
128FLT30.42157618
129MAPK100.41660400
130MAP3K130.41579300
131MAP3K120.41167523
132CAMK1D0.40914097
133SRC0.40317462
134MAPK40.40094877
135HIPK20.39833927

Predicted pathways (KEGG)

RankGene SetZ-score
1Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.23880665
2Synaptic vesicle cycle_Homo sapiens_hsa047212.15788269
3Circadian entrainment_Homo sapiens_hsa047132.11771828
4Insulin secretion_Homo sapiens_hsa049112.06068276
5Long-term potentiation_Homo sapiens_hsa047202.02432320
6Olfactory transduction_Homo sapiens_hsa047401.99986804
7Amphetamine addiction_Homo sapiens_hsa050311.93851985
8Nicotine addiction_Homo sapiens_hsa050331.93590478
9GABAergic synapse_Homo sapiens_hsa047271.89831778
10Aldosterone synthesis and secretion_Homo sapiens_hsa049251.87796913
11Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.81047613
12Dilated cardiomyopathy_Homo sapiens_hsa054141.77678315
13Gastric acid secretion_Homo sapiens_hsa049711.76746593
14Glutamatergic synapse_Homo sapiens_hsa047241.75247701
15Salivary secretion_Homo sapiens_hsa049701.74025296
16Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.69408290
17Dopaminergic synapse_Homo sapiens_hsa047281.69278595
18Morphine addiction_Homo sapiens_hsa050321.68133791
19Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.66641184
20Cholinergic synapse_Homo sapiens_hsa047251.62757188
21Cocaine addiction_Homo sapiens_hsa050301.55390707
22Notch signaling pathway_Homo sapiens_hsa043301.53655330
23Oxytocin signaling pathway_Homo sapiens_hsa049211.53545468
24Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.51172562
25Renin secretion_Homo sapiens_hsa049241.50770430
26Gap junction_Homo sapiens_hsa045401.44085062
27GnRH signaling pathway_Homo sapiens_hsa049121.43790951
28Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.42205817
29Type II diabetes mellitus_Homo sapiens_hsa049301.39490846
30Glioma_Homo sapiens_hsa052141.38042803
31Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.37401288
32Glycosaminoglycan degradation_Homo sapiens_hsa005311.34585708
33Estrogen signaling pathway_Homo sapiens_hsa049151.30111636
34Melanogenesis_Homo sapiens_hsa049161.27869574
35Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.27100467
36Calcium signaling pathway_Homo sapiens_hsa040201.27061011
37cGMP-PKG signaling pathway_Homo sapiens_hsa040221.25147560
38cAMP signaling pathway_Homo sapiens_hsa040241.23386863
39Taste transduction_Homo sapiens_hsa047421.21210718
40ECM-receptor interaction_Homo sapiens_hsa045121.19808202
41Long-term depression_Homo sapiens_hsa047301.18377018
42Axon guidance_Homo sapiens_hsa043601.18349602
43Nitrogen metabolism_Homo sapiens_hsa009101.18129876
44Focal adhesion_Homo sapiens_hsa045101.18039585
45Vascular smooth muscle contraction_Homo sapiens_hsa042701.11888093
46Prion diseases_Homo sapiens_hsa050201.11695226
47Dorso-ventral axis formation_Homo sapiens_hsa043201.08070939
48Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.05859538
49Serotonergic synapse_Homo sapiens_hsa047261.04204127
50Small cell lung cancer_Homo sapiens_hsa052221.01544355
51Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.01003977
52Cardiac muscle contraction_Homo sapiens_hsa042600.97617393
53Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.96420097
54ErbB signaling pathway_Homo sapiens_hsa040120.96337462
55Thyroid hormone signaling pathway_Homo sapiens_hsa049190.94757047
56Thyroid hormone synthesis_Homo sapiens_hsa049180.94125164
57Proteoglycans in cancer_Homo sapiens_hsa052050.93468878
58Phosphatidylinositol signaling system_Homo sapiens_hsa040700.92589347
59PI3K-Akt signaling pathway_Homo sapiens_hsa041510.92395675
60Phospholipase D signaling pathway_Homo sapiens_hsa040720.92151709
61mTOR signaling pathway_Homo sapiens_hsa041500.91782828
62Pancreatic secretion_Homo sapiens_hsa049720.90664855
63Other glycan degradation_Homo sapiens_hsa005110.88849815
64AMPK signaling pathway_Homo sapiens_hsa041520.87351781
65Glucagon signaling pathway_Homo sapiens_hsa049220.85955075
66Hippo signaling pathway_Homo sapiens_hsa043900.85937981
67MicroRNAs in cancer_Homo sapiens_hsa052060.85869236
68Rap1 signaling pathway_Homo sapiens_hsa040150.85109298
69Hedgehog signaling pathway_Homo sapiens_hsa043400.85031158
70Amoebiasis_Homo sapiens_hsa051460.83831296
71Tight junction_Homo sapiens_hsa045300.81958495
72Protein digestion and absorption_Homo sapiens_hsa049740.81887671
73Neurotrophin signaling pathway_Homo sapiens_hsa047220.81232383
74VEGF signaling pathway_Homo sapiens_hsa043700.79160474
75Pathways in cancer_Homo sapiens_hsa052000.77593386
76Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.76419269
77Carbohydrate digestion and absorption_Homo sapiens_hsa049730.74787670
78Endometrial cancer_Homo sapiens_hsa052130.74683819
79Leukocyte transendothelial migration_Homo sapiens_hsa046700.74464939
80Longevity regulating pathway - mammal_Homo sapiens_hsa042110.74449026
81Wnt signaling pathway_Homo sapiens_hsa043100.74445339
82Inositol phosphate metabolism_Homo sapiens_hsa005620.74043640
83Oocyte meiosis_Homo sapiens_hsa041140.73856183
84Adherens junction_Homo sapiens_hsa045200.73032920
85Bladder cancer_Homo sapiens_hsa052190.72014716
86Insulin signaling pathway_Homo sapiens_hsa049100.71623563
87MAPK signaling pathway_Homo sapiens_hsa040100.70796847
88Renal cell carcinoma_Homo sapiens_hsa052110.68118770
89TGF-beta signaling pathway_Homo sapiens_hsa043500.67626023
90Vibrio cholerae infection_Homo sapiens_hsa051100.67531123
91Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.66609352
92AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.66234057
93Basal cell carcinoma_Homo sapiens_hsa052170.65668346
94Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.65462951
95Endocytosis_Homo sapiens_hsa041440.64140275
96Choline metabolism in cancer_Homo sapiens_hsa052310.63347208
97Regulation of actin cytoskeleton_Homo sapiens_hsa048100.63192853
98Central carbon metabolism in cancer_Homo sapiens_hsa052300.62597777
99Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.62444192
100Non-small cell lung cancer_Homo sapiens_hsa052230.61210942
101Ovarian steroidogenesis_Homo sapiens_hsa049130.61054376
102Ras signaling pathway_Homo sapiens_hsa040140.60647872
103Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59972896
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59793306
105Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58764632
106Bile secretion_Homo sapiens_hsa049760.55593384
107Insulin resistance_Homo sapiens_hsa049310.54633438
108Prostate cancer_Homo sapiens_hsa052150.51855249
109Circadian rhythm_Homo sapiens_hsa047100.51195474
110Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51163689
111Chronic myeloid leukemia_Homo sapiens_hsa052200.50800009
112Platelet activation_Homo sapiens_hsa046110.50398437
113Melanoma_Homo sapiens_hsa052180.49950192
114Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.49845159

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