Rank | Gene Set | Z-score |
---|---|---|
1 | axon ensheathment in central nervous system (GO:0032291) | 7.09490541 |
2 | central nervous system myelination (GO:0022010) | 7.09490541 |
3 | cornea development in camera-type eye (GO:0061303) | 6.32604897 |
4 | establishment of protein localization to Golgi (GO:0072600) | 4.76114486 |
5 | neural tube formation (GO:0001841) | 4.69383524 |
6 | limb bud formation (GO:0060174) | 4.59381256 |
7 | protein targeting to Golgi (GO:0000042) | 4.47308125 |
8 | long-chain fatty acid biosynthetic process (GO:0042759) | 4.40053041 |
9 | myelination (GO:0042552) | 4.26038121 |
10 | ensheathment of neurons (GO:0007272) | 4.19023869 |
11 | axon ensheathment (GO:0008366) | 4.19023869 |
12 | regulation of timing of cell differentiation (GO:0048505) | 4.17423947 |
13 | presynaptic membrane assembly (GO:0097105) | 4.14094664 |
14 | negative regulation of neurotransmitter secretion (GO:0046929) | 4.08648884 |
15 | presynaptic membrane organization (GO:0097090) | 4.05538778 |
16 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.99307661 |
17 | eye photoreceptor cell differentiation (GO:0001754) | 3.91028216 |
18 | photoreceptor cell differentiation (GO:0046530) | 3.91028216 |
19 | positive regulation of cell fate commitment (GO:0010455) | 3.81961524 |
20 | regulation of development, heterochronic (GO:0040034) | 3.79412290 |
21 | hindbrain development (GO:0030902) | 3.73699402 |
22 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.73373188 |
23 | negative regulation of neurotransmitter transport (GO:0051589) | 3.68398930 |
24 | protein K11-linked deubiquitination (GO:0035871) | 3.58358956 |
25 | fatty acid elongation (GO:0030497) | 3.55452651 |
26 | DNA deamination (GO:0045006) | 3.52793870 |
27 | regulation of telomere maintenance (GO:0032204) | 3.31954454 |
28 | protein localization to Golgi apparatus (GO:0034067) | 3.31881398 |
29 | oligodendrocyte differentiation (GO:0048709) | 3.28621797 |
30 | asymmetric protein localization (GO:0008105) | 3.27950748 |
31 | neuron cell-cell adhesion (GO:0007158) | 3.25357242 |
32 | prenylation (GO:0097354) | 3.25001669 |
33 | protein prenylation (GO:0018342) | 3.25001669 |
34 | behavioral response to nicotine (GO:0035095) | 3.24274344 |
35 | regulation of collateral sprouting (GO:0048670) | 3.23219607 |
36 | epithelial cilium movement (GO:0003351) | 3.16394165 |
37 | regulation of pigment cell differentiation (GO:0050932) | 3.12927939 |
38 | regulation of cilium movement (GO:0003352) | 3.09995769 |
39 | histone H3-K4 trimethylation (GO:0080182) | 3.08098425 |
40 | negative regulation of protein localization to cell surface (GO:2000009) | 3.07046124 |
41 | glycerophospholipid catabolic process (GO:0046475) | 3.06041056 |
42 | photoreceptor cell development (GO:0042461) | 3.03909417 |
43 | microtubule anchoring (GO:0034453) | 3.02176049 |
44 | histone H2B ubiquitination (GO:0033523) | 3.02019368 |
45 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 3.00678557 |
46 | retina layer formation (GO:0010842) | 3.00650959 |
47 | RNA destabilization (GO:0050779) | 2.98365608 |
48 | response to redox state (GO:0051775) | 2.98114258 |
49 | apical protein localization (GO:0045176) | 2.97252112 |
50 | GPI anchor biosynthetic process (GO:0006506) | 2.96515530 |
51 | L-fucose catabolic process (GO:0042355) | 2.96239719 |
52 | fucose catabolic process (GO:0019317) | 2.96239719 |
53 | L-fucose metabolic process (GO:0042354) | 2.96239719 |
54 | transmission of nerve impulse (GO:0019226) | 2.94267039 |
55 | positive regulation of defense response to virus by host (GO:0002230) | 2.94119145 |
56 | axoneme assembly (GO:0035082) | 2.92048164 |
57 | reciprocal DNA recombination (GO:0035825) | 2.91565089 |
58 | reciprocal meiotic recombination (GO:0007131) | 2.91565089 |
59 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.90762395 |
60 | replication fork processing (GO:0031297) | 2.88931492 |
61 | centriole replication (GO:0007099) | 2.87828715 |
62 | cilium morphogenesis (GO:0060271) | 2.87207982 |
63 | negative regulation of execution phase of apoptosis (GO:1900118) | 2.86384953 |
64 | rRNA catabolic process (GO:0016075) | 2.83943986 |
65 | activated T cell proliferation (GO:0050798) | 2.82842655 |
66 | seminiferous tubule development (GO:0072520) | 2.82652708 |
67 | cellular response to interleukin-15 (GO:0071350) | 2.82504855 |
68 | dorsal/ventral axis specification (GO:0009950) | 2.81707269 |
69 | GPI anchor metabolic process (GO:0006505) | 2.81586972 |
70 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.80167873 |
71 | eye photoreceptor cell development (GO:0042462) | 2.79662333 |
72 | positive regulation of action potential (GO:0045760) | 2.79514684 |
73 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.78828717 |
74 | response to pheromone (GO:0019236) | 2.78491972 |
75 | response to epinephrine (GO:0071871) | 2.77036141 |
76 | embryonic epithelial tube formation (GO:0001838) | 2.74114947 |
77 | positive regulation of meiosis (GO:0045836) | 2.69055947 |
78 | astrocyte differentiation (GO:0048708) | 2.68689377 |
79 | lateral sprouting from an epithelium (GO:0060601) | 2.67488723 |
80 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.66896572 |
81 | cellular response to epinephrine stimulus (GO:0071872) | 2.66100064 |
82 | synapsis (GO:0007129) | 2.65721958 |
83 | mast cell degranulation (GO:0043303) | 2.63913094 |
84 | mast cell activation involved in immune response (GO:0002279) | 2.63913094 |
85 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 2.62010470 |
86 | negative regulation of mast cell activation (GO:0033004) | 2.61232130 |
87 | developmental pigmentation (GO:0048066) | 2.61181542 |
88 | negative regulation of axon extension (GO:0030517) | 2.60266810 |
89 | nucleotide transmembrane transport (GO:1901679) | 2.59898003 |
90 | cyclic nucleotide catabolic process (GO:0009214) | 2.55327161 |
91 | regulation of hexokinase activity (GO:1903299) | 2.54727909 |
92 | regulation of glucokinase activity (GO:0033131) | 2.54727909 |
93 | kynurenine metabolic process (GO:0070189) | 2.54424886 |
94 | interferon-gamma production (GO:0032609) | 2.53465865 |
95 | regulation of memory T cell differentiation (GO:0043380) | 2.52587771 |
96 | cranial nerve development (GO:0021545) | 2.52471597 |
97 | histone mRNA catabolic process (GO:0071044) | 2.52330114 |
98 | L-amino acid import (GO:0043092) | 2.52124310 |
99 | acrosome reaction (GO:0007340) | 2.52007110 |
100 | neuron recognition (GO:0008038) | 2.51671874 |
101 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.50801317 |
102 | myelin maintenance (GO:0043217) | 2.50353590 |
103 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.50264296 |
104 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.50250180 |
105 | epithelial tube formation (GO:0072175) | 2.50230059 |
106 | spinal cord motor neuron differentiation (GO:0021522) | 2.49395268 |
107 | positive regulation of meiotic cell cycle (GO:0051446) | 2.49166290 |
108 | cilium organization (GO:0044782) | 2.48586339 |
109 | regulation of meiosis I (GO:0060631) | 2.48540379 |
110 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.48424623 |
111 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.48424623 |
112 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.48300908 |
113 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.48292620 |
114 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.48292620 |
115 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.47518251 |
116 | protein polyglutamylation (GO:0018095) | 2.46947663 |
117 | multicellular organism reproduction (GO:0032504) | 2.46193030 |
118 | centriole assembly (GO:0098534) | 2.46105831 |
119 | positive regulation of neuroblast proliferation (GO:0002052) | 2.45727962 |
120 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.45239486 |
121 | keratinocyte development (GO:0003334) | 2.44874524 |
122 | adaptation of signaling pathway (GO:0023058) | 2.44825356 |
123 | neuron remodeling (GO:0016322) | 2.44529061 |
124 | negative regulation of myoblast differentiation (GO:0045662) | 2.44490669 |
125 | cilium movement (GO:0003341) | 2.44462918 |
126 | positive regulation of mRNA catabolic process (GO:0061014) | 2.43801731 |
127 | intraciliary transport (GO:0042073) | 2.43476226 |
128 | male meiosis I (GO:0007141) | 2.43025911 |
129 | somite development (GO:0061053) | 2.43015023 |
130 | regulation of somitogenesis (GO:0014807) | 2.42870040 |
131 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.42623274 |
132 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.42623274 |
133 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.42623274 |
134 | regulation of DNA endoreduplication (GO:0032875) | 2.41571392 |
135 | cytidine metabolic process (GO:0046087) | 2.41048781 |
136 | cytidine catabolic process (GO:0006216) | 2.41048781 |
137 | cytidine deamination (GO:0009972) | 2.41048781 |
138 | cilium assembly (GO:0042384) | 2.40660784 |
139 | pituitary gland development (GO:0021983) | 2.40563378 |
140 | organ growth (GO:0035265) | 2.40279262 |
141 | detection of light stimulus involved in visual perception (GO:0050908) | 2.39924794 |
142 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.39924794 |
143 | protein K63-linked deubiquitination (GO:0070536) | 2.39804763 |
144 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.39130069 |
145 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.39130069 |
146 | import into cell (GO:0098657) | 2.39047617 |
147 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.38049345 |
148 | ncRNA catabolic process (GO:0034661) | 2.37656177 |
149 | response to monoamine (GO:0071867) | 2.37271967 |
150 | response to catecholamine (GO:0071869) | 2.37271967 |
151 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.37047549 |
152 | forebrain neuron differentiation (GO:0021879) | 2.35557492 |
153 | olfactory bulb development (GO:0021772) | 2.35364579 |
154 | recombinational repair (GO:0000725) | 2.34068327 |
155 | double-strand break repair via homologous recombination (GO:0000724) | 2.33775565 |
156 | nonmotile primary cilium assembly (GO:0035058) | 2.32803122 |
157 | regulation of feeding behavior (GO:0060259) | 2.32516052 |
158 | negative regulation of JUN kinase activity (GO:0043508) | 2.31493541 |
159 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 2.30119462 |
160 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 2.30119462 |
161 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.29966888 |
162 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.29966888 |
163 | negative regulation of exocytosis (GO:0045920) | 2.29598305 |
164 | otic vesicle formation (GO:0030916) | 2.29029911 |
165 | startle response (GO:0001964) | 2.28992245 |
166 | magnesium ion transport (GO:0015693) | 2.27383622 |
167 | peripheral nervous system axon ensheathment (GO:0032292) | 2.25572701 |
168 | myelination in peripheral nervous system (GO:0022011) | 2.25572701 |
169 | regulation of axon regeneration (GO:0048679) | 2.25068375 |
170 | regulation of neuron projection regeneration (GO:0070570) | 2.25068375 |
171 | negative regulation of axonogenesis (GO:0050771) | 2.24020064 |
172 | dendrite development (GO:0016358) | 2.22161157 |
173 | glycolipid biosynthetic process (GO:0009247) | 2.21544719 |
174 | substantia nigra development (GO:0021762) | 2.18731294 |
175 | axonal fasciculation (GO:0007413) | 2.16678933 |
176 | postsynaptic membrane organization (GO:0001941) | 2.16644335 |
177 | cellular response to catecholamine stimulus (GO:0071870) | 2.14833372 |
178 | cellular response to monoamine stimulus (GO:0071868) | 2.14833372 |
179 | adult walking behavior (GO:0007628) | 2.14561981 |
180 | protein palmitoylation (GO:0018345) | 2.14514385 |
181 | neuronal ion channel clustering (GO:0045161) | 2.14496944 |
182 | negative regulation of transcription by competitive promoter binding (GO:0010944) | 2.13224608 |
183 | astrocyte development (GO:0014002) | 2.13131122 |
184 | ear development (GO:0043583) | 2.11626877 |
185 | regulation of dopamine metabolic process (GO:0042053) | 2.10857827 |
186 | regulation of catecholamine metabolic process (GO:0042069) | 2.10857827 |
Rank | Gene Set | Z-score |
---|---|---|
1 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.46240121 |
2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.39377037 |
3 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.01302343 |
4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.62167009 |
5 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.59911332 |
6 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.45175463 |
7 | * TAF15_26573619_Chip-Seq_HEK293_Human | 2.39327350 |
8 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.37856993 |
9 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.19509540 |
10 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.19021690 |
11 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.15109677 |
12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.12006700 |
13 | FUS_26573619_Chip-Seq_HEK293_Human | 2.07328333 |
14 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.04491457 |
15 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.03447318 |
16 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.03308087 |
17 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.00271938 |
18 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.95947330 |
19 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.93619574 |
20 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.90961180 |
21 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.90887242 |
22 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.88892632 |
23 | * PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.87981523 |
24 | P300_19829295_ChIP-Seq_ESCs_Human | 1.86580704 |
25 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.85847616 |
26 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.84558563 |
27 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.81465642 |
28 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.79370869 |
29 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.74758604 |
30 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.74758604 |
31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.74456308 |
32 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.73376058 |
33 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.72618590 |
34 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.72391084 |
35 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.72303005 |
36 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.71713724 |
37 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.70303710 |
38 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.70139985 |
39 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.69115718 |
40 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.68663193 |
41 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.68579982 |
42 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.68442423 |
43 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.67495811 |
44 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.65623099 |
45 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.65623099 |
46 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.65546734 |
47 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.63722872 |
48 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.62714562 |
49 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.62356865 |
50 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.61331214 |
51 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.61076671 |
52 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.60796585 |
53 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.60129438 |
54 | EWS_26573619_Chip-Seq_HEK293_Human | 1.58950002 |
55 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.57259477 |
56 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.55228883 |
57 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.54813251 |
58 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.53803952 |
59 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.53780812 |
60 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.51853134 |
61 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.50981212 |
62 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.50564055 |
63 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.48960736 |
64 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.48813103 |
65 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.48757036 |
66 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.48354857 |
67 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.47735662 |
68 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.45471043 |
69 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.45310059 |
70 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.44209909 |
71 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.44127811 |
72 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.43816345 |
73 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.43161829 |
74 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.42433684 |
75 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.41274675 |
76 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.41157174 |
77 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.40873739 |
78 | * FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.40363322 |
79 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.39872489 |
80 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.39272107 |
81 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.37161622 |
82 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.36932410 |
83 | AR_25329375_ChIP-Seq_VCAP_Human | 1.35424312 |
84 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.34180120 |
85 | STAT3_23295773_ChIP-Seq_U87_Human | 1.34157208 |
86 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.33752252 |
87 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.32732327 |
88 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.32208677 |
89 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.31565530 |
90 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.31322396 |
91 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.30573479 |
92 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.30205734 |
93 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.29675516 |
94 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.29213557 |
95 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.27739116 |
96 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.27022997 |
97 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26777149 |
98 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.26777149 |
99 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.26657767 |
100 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.26649773 |
101 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.25644030 |
102 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.25428159 |
103 | * TP53_22573176_ChIP-Seq_HFKS_Human | 1.25182058 |
104 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.24616054 |
105 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.24601151 |
106 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.21078481 |
107 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.19484226 |
108 | TP53_16413492_ChIP-PET_HCT116_Human | 1.17874169 |
109 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.17536161 |
110 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.17431430 |
111 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.17316588 |
112 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.17020519 |
113 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.16448769 |
114 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.16330891 |
115 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.15713049 |
116 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.14335201 |
117 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.13668396 |
118 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.12592724 |
119 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.12266682 |
120 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.12193552 |
121 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.11056320 |
122 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.10504216 |
123 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.10403608 |
124 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.09699016 |
125 | GATA3_26560356_Chip-Seq_TH2_Human | 1.09488568 |
126 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.09479838 |
127 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.09308760 |
128 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.09151685 |
129 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.09045813 |
130 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.08953924 |
131 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.08953924 |
132 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.08945474 |
133 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.08819934 |
134 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06610991 |
135 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.05172892 |
136 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.05047768 |
137 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.01731851 |
138 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.00611261 |
139 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.99314631 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000569_abnormal_digit_pigmentation | 3.92338709 |
2 | MP0003880_abnormal_central_pattern | 3.83727670 |
3 | MP0005409_darkened_coat_color | 3.80434309 |
4 | * MP0008877_abnormal_DNA_methylation | 3.46362863 |
5 | MP0001188_hyperpigmentation | 3.29952023 |
6 | MP0003136_yellow_coat_color | 3.17403213 |
7 | MP0005171_absent_coat_pigmentation | 2.96946505 |
8 | MP0000920_abnormal_myelination | 2.72234159 |
9 | MP0000566_synostosis | 2.59115524 |
10 | MP0008789_abnormal_olfactory_epithelium | 2.41708364 |
11 | MP0006292_abnormal_olfactory_placode | 2.30819030 |
12 | MP0004742_abnormal_vestibular_system | 2.20431303 |
13 | MP0000778_abnormal_nervous_system | 2.19315240 |
14 | MP0005423_abnormal_somatic_nervous | 2.16094371 |
15 | MP0001486_abnormal_startle_reflex | 2.13945963 |
16 | MP0004381_abnormal_hair_follicle | 2.09222815 |
17 | MP0004270_analgesia | 2.03522214 |
18 | MP0005499_abnormal_olfactory_system | 1.92527774 |
19 | MP0005394_taste/olfaction_phenotype | 1.92527774 |
20 | MP0003950_abnormal_plasma_membrane | 1.84558668 |
21 | MP0005257_abnormal_intraocular_pressure | 1.81798192 |
22 | MP0003195_calcinosis | 1.81407102 |
23 | MP0001529_abnormal_vocalization | 1.80398587 |
24 | MP0003724_increased_susceptibility_to | 1.78592570 |
25 | MP0002272_abnormal_nervous_system | 1.72084830 |
26 | MP0001905_abnormal_dopamine_level | 1.70471996 |
27 | MP0001485_abnormal_pinna_reflex | 1.70195732 |
28 | MP0005551_abnormal_eye_electrophysiolog | 1.65543830 |
29 | MP0000383_abnormal_hair_follicle | 1.64017963 |
30 | MP0005671_abnormal_response_to | 1.60571758 |
31 | MP0002009_preneoplasia | 1.59970424 |
32 | MP0009745_abnormal_behavioral_response | 1.54693281 |
33 | MP0004134_abnormal_chest_morphology | 1.53005019 |
34 | MP0004885_abnormal_endolymph | 1.52634179 |
35 | MP0001968_abnormal_touch/_nociception | 1.51538848 |
36 | MP0006072_abnormal_retinal_apoptosis | 1.51091403 |
37 | MP0005645_abnormal_hypothalamus_physiol | 1.50400781 |
38 | MP0005379_endocrine/exocrine_gland_phen | 1.49696467 |
39 | MP0000427_abnormal_hair_cycle | 1.41468735 |
40 | MP0010678_abnormal_skin_adnexa | 1.41190780 |
41 | MP0005646_abnormal_pituitary_gland | 1.37636110 |
42 | MP0001919_abnormal_reproductive_system | 1.37072091 |
43 | MP0001346_abnormal_lacrimal_gland | 1.36308734 |
44 | MP0002064_seizures | 1.34460362 |
45 | MP0009379_abnormal_foot_pigmentation | 1.34425309 |
46 | MP0002938_white_spotting | 1.34305705 |
47 | MP0000462_abnormal_digestive_system | 1.32885128 |
48 | MP0002160_abnormal_reproductive_system | 1.32355900 |
49 | MP0002734_abnormal_mechanical_nocicepti | 1.31853030 |
50 | MP0003937_abnormal_limbs/digits/tail_de | 1.31114659 |
51 | MP0002102_abnormal_ear_morphology | 1.29820693 |
52 | MP0008995_early_reproductive_senescence | 1.29734867 |
53 | MP0005389_reproductive_system_phenotype | 1.29677477 |
54 | MP0002163_abnormal_gland_morphology | 1.29230290 |
55 | MP0004142_abnormal_muscle_tone | 1.26592937 |
56 | MP0002928_abnormal_bile_duct | 1.25311056 |
57 | MP0009046_muscle_twitch | 1.24549854 |
58 | MP0002572_abnormal_emotion/affect_behav | 1.22605082 |
59 | MP0001963_abnormal_hearing_physiology | 1.21135874 |
60 | MP0000631_abnormal_neuroendocrine_gland | 1.20435001 |
61 | MP0001502_abnormal_circadian_rhythm | 1.20113350 |
62 | MP0003635_abnormal_synaptic_transmissio | 1.19170529 |
63 | MP0000026_abnormal_inner_ear | 1.18571012 |
64 | MP0000015_abnormal_ear_pigmentation | 1.18170869 |
65 | MP0002736_abnormal_nociception_after | 1.17373739 |
66 | MP0001440_abnormal_grooming_behavior | 1.15318173 |
67 | MP0008058_abnormal_DNA_repair | 1.14896720 |
68 | MP0003938_abnormal_ear_development | 1.13592046 |
69 | MP0006276_abnormal_autonomic_nervous | 1.13485580 |
70 | MP0001986_abnormal_taste_sensitivity | 1.12203172 |
71 | MP0002752_abnormal_somatic_nervous | 1.11523112 |
72 | MP0002882_abnormal_neuron_morphology | 1.11042498 |
73 | MP0004133_heterotaxia | 1.10991634 |
74 | MP0009250_abnormal_appendicular_skeleto | 1.10584585 |
75 | MP0008057_abnormal_DNA_replication | 1.09656527 |
76 | MP0002277_abnormal_respiratory_mucosa | 1.09437744 |
77 | MP0003122_maternal_imprinting | 1.09372749 |
78 | MP0005253_abnormal_eye_physiology | 1.08384998 |
79 | MP0000762_abnormal_tongue_morphology | 1.07924195 |
80 | MP0001177_atelectasis | 1.07354637 |
81 | * MP0003787_abnormal_imprinting | 1.07282511 |
82 | MP0002234_abnormal_pharynx_morphology | 1.07125361 |
83 | MP0002557_abnormal_social/conspecific_i | 1.06017571 |
84 | MP0000049_abnormal_middle_ear | 1.05350327 |
85 | MP0001800_abnormal_humoral_immune | 1.04380318 |
86 | MP0001984_abnormal_olfaction | 1.03135428 |
87 | MP0002063_abnormal_learning/memory/cond | 1.02910374 |
88 | MP0002909_abnormal_adrenal_gland | 1.02629149 |
89 | MP0002067_abnormal_sensory_capabilities | 1.02150112 |
90 | MP0002184_abnormal_innervation | 1.00895191 |
91 | MP0008872_abnormal_physiological_respon | 0.99455581 |
92 | MP0000955_abnormal_spinal_cord | 0.99441729 |
93 | MP0005075_abnormal_melanosome_morpholog | 0.99210435 |
94 | MP0005084_abnormal_gallbladder_morpholo | 0.99096188 |
95 | MP0003385_abnormal_body_wall | 0.97105994 |
96 | MP0004147_increased_porphyrin_level | 0.96436777 |
97 | MP0003632_abnormal_nervous_system | 0.94941927 |
98 | MP0002229_neurodegeneration | 0.94411024 |
99 | MP0003634_abnormal_glial_cell | 0.94138532 |
100 | MP0001851_eye_inflammation | 0.94097700 |
101 | MP0003690_abnormal_glial_cell | 0.93800445 |
102 | MP0001501_abnormal_sleep_pattern | 0.93520925 |
103 | MP0005195_abnormal_posterior_eye | 0.93381230 |
104 | MP0001299_abnormal_eye_distance/ | 0.92375392 |
105 | MP0003755_abnormal_palate_morphology | 0.91821945 |
106 | MP0001929_abnormal_gametogenesis | 0.91005288 |
107 | MP0005410_abnormal_fertilization | 0.90716201 |
108 | MP0000647_abnormal_sebaceous_gland | 0.90635831 |
109 | MP0002837_dystrophic_cardiac_calcinosis | 0.90156694 |
110 | MP0003698_abnormal_male_reproductive | 0.90072872 |
111 | MP0002177_abnormal_outer_ear | 0.88201124 |
112 | MP0002233_abnormal_nose_morphology | 0.88089954 |
113 | MP0002876_abnormal_thyroid_physiology | 0.87405911 |
114 | MP0003763_abnormal_thymus_physiology | 0.87209652 |
115 | MP0008961_abnormal_basal_metabolism | 0.87182525 |
116 | MP0005174_abnormal_tail_pigmentation | 0.87032857 |
117 | MP0008569_lethality_at_weaning | 0.86250570 |
118 | MP0004859_abnormal_synaptic_plasticity | 0.85023096 |
119 | MP0005310_abnormal_salivary_gland | 0.84728406 |
120 | MP0003890_abnormal_embryonic-extraembry | 0.84110406 |
121 | MP0002751_abnormal_autonomic_nervous | 0.84035330 |
122 | MP0002249_abnormal_larynx_morphology | 0.80411837 |
123 | MP0001324_abnormal_eye_pigmentation | 0.79758317 |
124 | MP0006054_spinal_hemorrhage | 0.78729955 |
125 | MP0005391_vision/eye_phenotype | 0.77786758 |
126 | MP0002735_abnormal_chemical_nociception | 0.77399305 |
127 | MP0002210_abnormal_sex_determination | 0.75035897 |
128 | MP0002638_abnormal_pupillary_reflex | 0.73401703 |
129 | MP0004924_abnormal_behavior | 0.73088760 |
130 | MP0005386_behavior/neurological_phenoty | 0.73088760 |
131 | MP0000372_irregular_coat_pigmentation | 0.72879627 |
132 | * MP0003121_genomic_imprinting | 0.72858253 |
133 | MP0002723_abnormal_immune_serum | 0.72537164 |
134 | MP0000653_abnormal_sex_gland | 0.72106107 |
135 | MP0002095_abnormal_skin_pigmentation | 0.70902042 |
136 | MP0000613_abnormal_salivary_gland | 0.70896453 |
137 | MP0001970_abnormal_pain_threshold | 0.70153902 |
138 | MP0002152_abnormal_brain_morphology | 0.69928754 |
139 | MP0010386_abnormal_urinary_bladder | 0.69593533 |
140 | MP0002693_abnormal_pancreas_physiology | 0.69312647 |
141 | MP0003567_abnormal_fetal_cardiomyocyte | 0.68271356 |
142 | MP0001119_abnormal_female_reproductive | 0.68008824 |
143 | MP0003252_abnormal_bile_duct | 0.66882109 |
144 | MP0001944_abnormal_pancreas_morphology | 0.66340181 |
145 | MP0001145_abnormal_male_reproductive | 0.65572261 |
146 | MP0002420_abnormal_adaptive_immunity | 0.63330887 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 3.84140599 |
2 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 3.84140599 |
3 | Pancreatic cysts (HP:0001737) | 3.66277213 |
4 | Hypoplasia of the fovea (HP:0007750) | 3.58609173 |
5 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 3.58609173 |
6 | Parakeratosis (HP:0001036) | 3.27881166 |
7 | True hermaphroditism (HP:0010459) | 3.13526222 |
8 | White forelock (HP:0002211) | 3.08907193 |
9 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.99622966 |
10 | Absent/shortened dynein arms (HP:0200106) | 2.99622966 |
11 | Abnormality of the renal cortex (HP:0011035) | 2.96286535 |
12 | Abnormality of the fovea (HP:0000493) | 2.94400042 |
13 | Abnormal ciliary motility (HP:0012262) | 2.94274245 |
14 | Patchy hypopigmentation of hair (HP:0011365) | 2.88891529 |
15 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.84746119 |
16 | Thyroiditis (HP:0100646) | 2.84329272 |
17 | Hyperventilation (HP:0002883) | 2.83200349 |
18 | Neurofibrillary tangles (HP:0002185) | 2.82492365 |
19 | Sensory axonal neuropathy (HP:0003390) | 2.80958471 |
20 | Abnormality of incisor morphology (HP:0011063) | 2.79893675 |
21 | Congenital stationary night blindness (HP:0007642) | 2.79783803 |
22 | Renal cortical cysts (HP:0000803) | 2.79756725 |
23 | Abnormal hair whorl (HP:0010721) | 2.77998472 |
24 | Cupped ear (HP:0000378) | 2.77667004 |
25 | Alacrima (HP:0000522) | 2.76891678 |
26 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.68629871 |
27 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.65827681 |
28 | Thickened helices (HP:0000391) | 2.61456470 |
29 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.60749687 |
30 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.58035934 |
31 | Decreased lacrimation (HP:0000633) | 2.56536120 |
32 | Abnormality of the corticospinal tract (HP:0002492) | 2.55673852 |
33 | Chronic hepatic failure (HP:0100626) | 2.55254968 |
34 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.54091556 |
35 | Abnormality of T cell number (HP:0011839) | 2.51302002 |
36 | Gaze-evoked nystagmus (HP:0000640) | 2.51013455 |
37 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.50775747 |
38 | Genetic anticipation (HP:0003743) | 2.47350998 |
39 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.46046699 |
40 | Septo-optic dysplasia (HP:0100842) | 2.42697001 |
41 | Progressive cerebellar ataxia (HP:0002073) | 2.41899370 |
42 | Absent speech (HP:0001344) | 2.40636699 |
43 | Absent septum pellucidum (HP:0001331) | 2.39996995 |
44 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.39992999 |
45 | Congenital sensorineural hearing impairment (HP:0008527) | 2.39341685 |
46 | Stomatitis (HP:0010280) | 2.36461796 |
47 | Aplasia cutis congenita (HP:0001057) | 2.35941647 |
48 | Severe combined immunodeficiency (HP:0004430) | 2.33844953 |
49 | Lip pit (HP:0100267) | 2.32994972 |
50 | Abnormality of eosinophils (HP:0001879) | 2.32275659 |
51 | Attenuation of retinal blood vessels (HP:0007843) | 2.32078325 |
52 | Abnormality of the septum pellucidum (HP:0007375) | 2.31828122 |
53 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.30010875 |
54 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.30010875 |
55 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.28922891 |
56 | Anteriorly placed anus (HP:0001545) | 2.28792537 |
57 | Widely spaced teeth (HP:0000687) | 2.28626217 |
58 | T lymphocytopenia (HP:0005403) | 2.28105058 |
59 | Stomach cancer (HP:0012126) | 2.23289817 |
60 | Tubulointerstitial nephritis (HP:0001970) | 2.21378392 |
61 | Metaphyseal dysplasia (HP:0100255) | 2.20387792 |
62 | Optic nerve coloboma (HP:0000588) | 2.17912333 |
63 | Abnormal auditory evoked potentials (HP:0006958) | 2.14796968 |
64 | Conical tooth (HP:0000698) | 2.12175351 |
65 | Volvulus (HP:0002580) | 2.08981138 |
66 | Abnormality of the nasolacrimal system (HP:0000614) | 2.08806332 |
67 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.07981913 |
68 | Abnormality of midbrain morphology (HP:0002418) | 2.07765912 |
69 | Molar tooth sign on MRI (HP:0002419) | 2.07765912 |
70 | Nasolacrimal duct obstruction (HP:0000579) | 2.06912708 |
71 | Abnormality of the parietal bone (HP:0002696) | 2.06883770 |
72 | Cystic liver disease (HP:0006706) | 2.06715877 |
73 | Retinal dysplasia (HP:0007973) | 2.04509136 |
74 | Peripheral hypomyelination (HP:0007182) | 2.04378105 |
75 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.02350077 |
76 | IgG deficiency (HP:0004315) | 2.02274961 |
77 | Alveolar cell carcinoma (HP:0006519) | 2.01363988 |
78 | Hip dysplasia (HP:0001385) | 2.01318021 |
79 | Genital tract atresia (HP:0001827) | 1.99554492 |
80 | Postaxial foot polydactyly (HP:0001830) | 1.99447090 |
81 | Chin dimple (HP:0010751) | 1.97045832 |
82 | Protruding tongue (HP:0010808) | 1.96993854 |
83 | Keratitis (HP:0000491) | 1.95065255 |
84 | Duplicated collecting system (HP:0000081) | 1.94586194 |
85 | Long nose (HP:0003189) | 1.92451077 |
86 | Mixed hearing impairment (HP:0000410) | 1.91889346 |
87 | Vaginal atresia (HP:0000148) | 1.91815424 |
88 | Abnormality of the lacrimal duct (HP:0011481) | 1.91241635 |
89 | Decreased central vision (HP:0007663) | 1.91187526 |
90 | Abnormality of the labia minora (HP:0012880) | 1.91046651 |
91 | Tented upper lip vermilion (HP:0010804) | 1.90666328 |
92 | Short tibia (HP:0005736) | 1.90629121 |
93 | Optic nerve hypoplasia (HP:0000609) | 1.90584718 |
94 | Abnormality of the nasal septum (HP:0000419) | 1.90266353 |
95 | Onion bulb formation (HP:0003383) | 1.89877890 |
96 | Anomalous pulmonary venous return (HP:0010772) | 1.88080917 |
97 | Abnormality of chromosome stability (HP:0003220) | 1.87303137 |
98 | Adrenal hypoplasia (HP:0000835) | 1.87231843 |
99 | Median cleft lip (HP:0000161) | 1.86232036 |
100 | Abnormality of the columella (HP:0009929) | 1.85257367 |
101 | Fair hair (HP:0002286) | 1.84005500 |
102 | Truncal obesity (HP:0001956) | 1.83539728 |
103 | Neoplasm of the adrenal cortex (HP:0100641) | 1.82543961 |
104 | Gastroesophageal reflux (HP:0002020) | 1.82522680 |
105 | Myelomeningocele (HP:0002475) | 1.82126769 |
106 | Medial flaring of the eyebrow (HP:0010747) | 1.82001353 |
107 | Congenital hepatic fibrosis (HP:0002612) | 1.80814285 |
108 | Overfolded helix (HP:0000396) | 1.80138580 |
109 | Tubular atrophy (HP:0000092) | 1.80119255 |
110 | Aqueductal stenosis (HP:0002410) | 1.79135563 |
111 | Abnormality of the incisor (HP:0000676) | 1.78535344 |
112 | Gait imbalance (HP:0002141) | 1.78090098 |
113 | Hypoplastic ischia (HP:0003175) | 1.77648928 |
114 | Slow saccadic eye movements (HP:0000514) | 1.77641065 |
115 | Oligodactyly (hands) (HP:0001180) | 1.77402750 |
116 | Male pseudohermaphroditism (HP:0000037) | 1.77059246 |
117 | Abnormality of the renal collecting system (HP:0004742) | 1.77030733 |
118 | Abnormality of the renal medulla (HP:0100957) | 1.76359381 |
119 | Epileptic encephalopathy (HP:0200134) | 1.76194063 |
120 | Papillary thyroid carcinoma (HP:0002895) | 1.76169918 |
121 | Lissencephaly (HP:0001339) | 1.74978674 |
122 | Focal motor seizures (HP:0011153) | 1.74325868 |
123 | Asplenia (HP:0001746) | 1.73899128 |
124 | Intestinal atresia (HP:0011100) | 1.73628428 |
125 | Narrow forehead (HP:0000341) | 1.73009974 |
126 | Dysmetria (HP:0001310) | 1.72892586 |
127 | Premature skin wrinkling (HP:0100678) | 1.72226860 |
128 | Abnormality of the axillary hair (HP:0100134) | 1.71998831 |
129 | Abnormality of secondary sexual hair (HP:0009888) | 1.71998831 |
130 | Atelectasis (HP:0100750) | 1.70632345 |
131 | Hypoplasia of the iris (HP:0007676) | 1.70358065 |
132 | Broad-based gait (HP:0002136) | 1.70189952 |
133 | Prostate neoplasm (HP:0100787) | 1.70075169 |
134 | Polydipsia (HP:0001959) | 1.70007530 |
135 | Abnormal drinking behavior (HP:0030082) | 1.70007530 |
136 | Nephronophthisis (HP:0000090) | 1.69858335 |
137 | Split foot (HP:0001839) | 1.69139763 |
138 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.68962928 |
139 | Congenital primary aphakia (HP:0007707) | 1.67738319 |
140 | Abnormality of the pulmonary veins (HP:0011718) | 1.67443358 |
141 | Growth hormone deficiency (HP:0000824) | 1.66810296 |
142 | Type II lissencephaly (HP:0007260) | 1.66750840 |
143 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.66732068 |
144 | Pendular nystagmus (HP:0012043) | 1.66537905 |
145 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.66503167 |
146 | Ectopic anus (HP:0004397) | 1.65565423 |
147 | Postaxial hand polydactyly (HP:0001162) | 1.65514252 |
148 | Hypoplastic iliac wings (HP:0002866) | 1.65469972 |
149 | Midline defect of the nose (HP:0004122) | 1.65406801 |
150 | Scanning speech (HP:0002168) | 1.65339887 |
151 | Abnormality of T cells (HP:0002843) | 1.64361599 |
152 | Inability to walk (HP:0002540) | 1.64289527 |
153 | Excessive salivation (HP:0003781) | 1.64120218 |
154 | Drooling (HP:0002307) | 1.64120218 |
155 | Abolished electroretinogram (ERG) (HP:0000550) | 1.63303368 |
156 | Preaxial hand polydactyly (HP:0001177) | 1.62381354 |
157 | Eosinophilia (HP:0001880) | 1.62314437 |
158 | Pancreatic fibrosis (HP:0100732) | 1.62137598 |
159 | Aplasia involving bones of the extremities (HP:0009825) | 1.62075442 |
160 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.62075442 |
161 | Aplasia of the phalanges of the hand (HP:0009802) | 1.62075442 |
162 | Abnormality of salivation (HP:0100755) | 1.62013292 |
163 | Supernumerary ribs (HP:0005815) | 1.61447049 |
164 | Blue irides (HP:0000635) | 1.61419985 |
165 | Constricted visual fields (HP:0001133) | 1.61375311 |
166 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.60571460 |
167 | Febrile seizures (HP:0002373) | 1.60497552 |
168 | Hypochromic microcytic anemia (HP:0004840) | 1.60030382 |
169 | Small hand (HP:0200055) | 1.60005757 |
170 | Abnormality of molar (HP:0011077) | 1.59895555 |
171 | Abnormality of molar morphology (HP:0011070) | 1.59895555 |
172 | Increased corneal curvature (HP:0100692) | 1.59343836 |
173 | Highly arched eyebrow (HP:0002553) | 1.59311829 |
174 | Autoimmune hemolytic anemia (HP:0001890) | 1.58967420 |
175 | Abnormality of the ischium (HP:0003174) | 1.58328500 |
176 | Pachygyria (HP:0001302) | 1.54631506 |
177 | Sloping forehead (HP:0000340) | 1.54554577 |
178 | Abnormality of macular pigmentation (HP:0008002) | 1.54365010 |
179 | Prominent nasal bridge (HP:0000426) | 1.53956074 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 4.98326585 |
2 | STK39 | 3.98182775 |
3 | TNIK | 3.69284289 |
4 | MAP4K2 | 2.82234516 |
5 | CASK | 2.70581421 |
6 | OXSR1 | 2.64752134 |
7 | BCR | 2.51452355 |
8 | TAOK3 | 2.39998105 |
9 | NEK6 | 2.16276679 |
10 | PKN1 | 2.16178436 |
11 | MAP3K4 | 1.96819417 |
12 | BMPR1B | 1.91774049 |
13 | PNCK | 1.87647538 |
14 | EPHB1 | 1.80842979 |
15 | PTK2B | 1.77480755 |
16 | CLK1 | 1.74989467 |
17 | ACVR1B | 1.70642487 |
18 | BRD4 | 1.67279950 |
19 | WNK1 | 1.56103267 |
20 | AKT3 | 1.56013037 |
21 | PBK | 1.55507190 |
22 | FGFR2 | 1.54537687 |
23 | MKNK2 | 1.53305050 |
24 | WNK4 | 1.52528122 |
25 | BMPR2 | 1.49630410 |
26 | IRAK1 | 1.47880390 |
27 | NUAK1 | 1.45062846 |
28 | IRAK4 | 1.41377454 |
29 | CSNK1A1L | 1.35919256 |
30 | GRK7 | 1.35172161 |
31 | INSRR | 1.33946706 |
32 | PLK4 | 1.31523923 |
33 | MAPK13 | 1.31008386 |
34 | STK38L | 1.28994389 |
35 | CDK3 | 1.28965842 |
36 | MKNK1 | 1.26152629 |
37 | TXK | 1.22958672 |
38 | PRPF4B | 1.18677216 |
39 | MAPK15 | 1.16047974 |
40 | PINK1 | 1.15879121 |
41 | EPHA4 | 1.15718199 |
42 | TRIM28 | 1.11973539 |
43 | MAP2K7 | 1.11912709 |
44 | CSNK1G3 | 1.06463334 |
45 | STK16 | 1.05574675 |
46 | MAP3K14 | 1.04556104 |
47 | SGK223 | 1.02670156 |
48 | SGK494 | 1.02670156 |
49 | MST4 | 1.00519989 |
50 | CAMKK2 | 0.99363536 |
51 | MARK3 | 0.98846340 |
52 | CAMK2B | 0.98665086 |
53 | PRKCQ | 0.98435049 |
54 | IRAK2 | 0.97974332 |
55 | MARK1 | 0.97441768 |
56 | MARK2 | 0.96288305 |
57 | SIK3 | 0.95888080 |
58 | MAPKAPK5 | 0.95402409 |
59 | BRSK2 | 0.94225162 |
60 | UHMK1 | 0.92438121 |
61 | ZAK | 0.91117704 |
62 | TLK1 | 0.90909640 |
63 | CSNK1G1 | 0.90340600 |
64 | ROCK2 | 0.89641104 |
65 | NLK | 0.89490355 |
66 | CSNK1G2 | 0.87532182 |
67 | YES1 | 0.86888115 |
68 | CHUK | 0.85874704 |
69 | KIT | 0.85299317 |
70 | DYRK1A | 0.84496654 |
71 | IKBKB | 0.80755169 |
72 | DYRK3 | 0.80194790 |
73 | NTRK3 | 0.79583833 |
74 | DYRK2 | 0.79142136 |
75 | CAMK2D | 0.79027598 |
76 | PIK3CG | 0.77734620 |
77 | FES | 0.77071512 |
78 | GRK1 | 0.76124874 |
79 | BLK | 0.75683465 |
80 | PRKCE | 0.75237962 |
81 | ADRBK2 | 0.74494372 |
82 | SRPK1 | 0.70972341 |
83 | CDK19 | 0.70097572 |
84 | WEE1 | 0.69066191 |
85 | FGR | 0.67955088 |
86 | TAF1 | 0.67610064 |
87 | EIF2AK2 | 0.67415312 |
88 | RPS6KA5 | 0.66058387 |
89 | PRKCG | 0.65997691 |
90 | EPHA3 | 0.65901910 |
91 | MAP2K4 | 0.65801312 |
92 | TRPM7 | 0.64291841 |
93 | ERBB3 | 0.63738152 |
94 | MELK | 0.63246011 |
95 | CAMK2A | 0.62583174 |
96 | KSR1 | 0.62168705 |
97 | STK3 | 0.60885956 |
98 | MAPK7 | 0.58974130 |
99 | PIK3CA | 0.58606567 |
100 | ERBB2 | 0.57302451 |
101 | CAMK1G | 0.56711051 |
102 | MAP4K1 | 0.56447244 |
103 | TNK2 | 0.55654963 |
104 | NME1 | 0.55016139 |
105 | PRKG1 | 0.54930911 |
106 | GRK6 | 0.54590308 |
107 | MET | 0.53610323 |
108 | MAP3K13 | 0.52935094 |
109 | BTK | 0.52382543 |
110 | CDK9 | 0.52248713 |
111 | MATK | 0.51380499 |
112 | VRK1 | 0.51318396 |
113 | PAK3 | 0.51287548 |
114 | STK11 | 0.50475324 |
115 | ADRBK1 | 0.48931130 |
116 | SIK2 | 0.48148914 |
117 | RIPK4 | 0.47855149 |
118 | WNK3 | 0.47596294 |
119 | CDK5 | 0.47319423 |
120 | PLK2 | 0.47316938 |
121 | SGK1 | 0.46951533 |
122 | CDK8 | 0.46756056 |
123 | SYK | 0.46175115 |
124 | HIPK2 | 0.45375523 |
125 | CSNK1D | 0.44253662 |
126 | IKBKE | 0.43698473 |
127 | NTRK2 | 0.43585759 |
128 | DMPK | 0.43585553 |
129 | ITK | 0.43036528 |
130 | LYN | 0.42773028 |
131 | SGK2 | 0.42114105 |
132 | LCK | 0.40984033 |
133 | JAK1 | 0.40283236 |
134 | IRAK3 | 0.39012384 |
135 | FYN | 0.38234714 |
136 | TEC | 0.37800397 |
137 | CSNK1A1 | 0.35016622 |
138 | MAP3K6 | 0.34867831 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.60979792 |
2 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.40589530 |
3 | Homologous recombination_Homo sapiens_hsa03440 | 2.21282487 |
4 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.19107338 |
5 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.17908996 |
6 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.14151747 |
7 | Protein export_Homo sapiens_hsa03060 | 2.08508200 |
8 | Axon guidance_Homo sapiens_hsa04360 | 1.93640833 |
9 | Nicotine addiction_Homo sapiens_hsa05033 | 1.88235475 |
10 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.87940627 |
11 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.82818340 |
12 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.77585537 |
13 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.76636126 |
14 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.75516495 |
15 | RNA degradation_Homo sapiens_hsa03018 | 1.74300842 |
16 | Phototransduction_Homo sapiens_hsa04744 | 1.67884157 |
17 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.60594281 |
18 | Morphine addiction_Homo sapiens_hsa05032 | 1.59455228 |
19 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.57188252 |
20 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.56479757 |
21 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.54965635 |
22 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.54845624 |
23 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.37769872 |
24 | GABAergic synapse_Homo sapiens_hsa04727 | 1.32784978 |
25 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.31894088 |
26 | Circadian entrainment_Homo sapiens_hsa04713 | 1.29561139 |
27 | Taste transduction_Homo sapiens_hsa04742 | 1.27567420 |
28 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.22201662 |
29 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.21956152 |
30 | Measles_Homo sapiens_hsa05162 | 1.20108101 |
31 | Long-term depression_Homo sapiens_hsa04730 | 1.18877028 |
32 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.16992674 |
33 | Allograft rejection_Homo sapiens_hsa05330 | 1.15832501 |
34 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.10789128 |
35 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.05768923 |
36 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.05327647 |
37 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.03228855 |
38 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.02814705 |
39 | Cocaine addiction_Homo sapiens_hsa05030 | 1.02770645 |
40 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.02240797 |
41 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.01406491 |
42 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.00806488 |
43 | Basal transcription factors_Homo sapiens_hsa03022 | 0.99686567 |
44 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.97489937 |
45 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.96901376 |
46 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.96839137 |
47 | Salivary secretion_Homo sapiens_hsa04970 | 0.96324592 |
48 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.96234590 |
49 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.95700034 |
50 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.93465011 |
51 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.93352742 |
52 | Renin secretion_Homo sapiens_hsa04924 | 0.92894116 |
53 | ABC transporters_Homo sapiens_hsa02010 | 0.91768265 |
54 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.89370197 |
55 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.88759327 |
56 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.85512226 |
57 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.83859101 |
58 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.83129544 |
59 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.82523471 |
60 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.81372762 |
61 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.80516259 |
62 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.79925989 |
63 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.79860926 |
64 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.79585921 |
65 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.79449933 |
66 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.78244536 |
67 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.77212791 |
68 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.76821702 |
69 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.76744554 |
70 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.76114815 |
71 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.76112435 |
72 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.75820302 |
73 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.75779189 |
74 | Long-term potentiation_Homo sapiens_hsa04720 | 0.75295132 |
75 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.74852153 |
76 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.74380054 |
77 | Insulin secretion_Homo sapiens_hsa04911 | 0.74152682 |
78 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.73935193 |
79 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.73458259 |
80 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.72483220 |
81 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.72129269 |
82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.70270498 |
83 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.70158233 |
84 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.70081812 |
85 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.69570875 |
86 | Malaria_Homo sapiens_hsa05144 | 0.69019531 |
87 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.68693132 |
88 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.68500254 |
89 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.68339527 |
90 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.67947449 |
91 | Prostate cancer_Homo sapiens_hsa05215 | 0.66805446 |
92 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.66593089 |
93 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.66477357 |
94 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.66011995 |
95 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.65156489 |
96 | Alcoholism_Homo sapiens_hsa05034 | 0.64921035 |
97 | Melanogenesis_Homo sapiens_hsa04916 | 0.64625127 |
98 | RNA polymerase_Homo sapiens_hsa03020 | 0.64533541 |
99 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.63634686 |
100 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.63540645 |
101 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.62954299 |
102 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.62893307 |
103 | Alzheimers disease_Homo sapiens_hsa05010 | 0.61535582 |
104 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.60793523 |
105 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.59898658 |
106 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.59470063 |
107 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.59363816 |
108 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.58693499 |
109 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.58272513 |
110 | Tight junction_Homo sapiens_hsa04530 | 0.57928381 |
111 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.57006561 |
112 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.56800119 |
113 | Asthma_Homo sapiens_hsa05310 | 0.55506114 |
114 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.55444602 |
115 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.54731945 |
116 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.54073356 |
117 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.53227450 |
118 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.52807062 |
119 | Olfactory transduction_Homo sapiens_hsa04740 | 0.52614580 |
120 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.52254937 |
121 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.52233689 |
122 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.51308833 |
123 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.49329187 |
124 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.48500336 |
125 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.48284810 |
126 | Peroxisome_Homo sapiens_hsa04146 | 0.47741413 |
127 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.47424385 |
128 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.47348564 |
129 | Legionellosis_Homo sapiens_hsa05134 | 0.46479899 |
130 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.46119168 |
131 | Circadian rhythm_Homo sapiens_hsa04710 | 0.45357877 |
132 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.45270042 |
133 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.44880103 |
134 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.44081025 |
135 | Leishmaniasis_Homo sapiens_hsa05140 | 0.43611604 |
136 | RNA transport_Homo sapiens_hsa03013 | 0.42689487 |
137 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.42603544 |
138 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.40100154 |
139 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.35251812 |
140 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.34011189 |
141 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.33390950 |