ARL14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vitamin transmembrane transport (GO:0035461)8.84495261
2desmosome organization (GO:0002934)7.29165480
3bundle of His cell to Purkinje myocyte communication (GO:0086069)6.31129988
4bile acid and bile salt transport (GO:0015721)5.95274150
53-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)5.85459177
6purine ribonucleoside bisphosphate metabolic process (GO:0034035)5.85459177
7intestinal absorption (GO:0050892)5.72252828
8maintenance of gastrointestinal epithelium (GO:0030277)5.25994826
9epoxygenase P450 pathway (GO:0019373)5.23719688
10cytidine metabolic process (GO:0046087)5.00213569
11cytidine catabolic process (GO:0006216)5.00213569
12cytidine deamination (GO:0009972)5.00213569
13drug catabolic process (GO:0042737)4.94508391
14macrophage chemotaxis (GO:0048246)4.92537966
15regulation of guanylate cyclase activity (GO:0031282)4.89063917
16positive regulation of fatty acid oxidation (GO:0046321)4.87522503
17flavonoid metabolic process (GO:0009812)4.79418829
18actin filament depolymerization (GO:0030042)4.75748503
19exogenous drug catabolic process (GO:0042738)4.62926632
20positive regulation of guanylate cyclase activity (GO:0031284)4.62785950
21sulfur compound transport (GO:0072348)4.56159946
22cellular glucuronidation (GO:0052695)4.51108398
23primary alcohol catabolic process (GO:0034310)4.46530308
24fat-soluble vitamin biosynthetic process (GO:0042362)4.42213552
25intestinal cholesterol absorption (GO:0030299)4.36955392
26positive regulation of fatty acid beta-oxidation (GO:0032000)4.33667816
27regulation of systemic arterial blood pressure by hormone (GO:0001990)4.33556453
28regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)4.33556453
29endocrine process (GO:0050886)4.33556453
30regulation of cGMP biosynthetic process (GO:0030826)4.29416066
31epithelial structure maintenance (GO:0010669)4.27885624
32angiotensin maturation (GO:0002003)4.27304757
33calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.15953950
34ethanol metabolic process (GO:0006067)4.13794586
35galactose catabolic process (GO:0019388)4.12858187
36sulfur amino acid catabolic process (GO:0000098)4.11370186
37azole transport (GO:0045117)4.11136106
38positive regulation of cGMP biosynthetic process (GO:0030828)4.10449741
39uronic acid metabolic process (GO:0006063)4.00777439
40glucuronate metabolic process (GO:0019585)4.00777439
41lipoprotein metabolic process (GO:0042157)3.98038487
42nitric oxide metabolic process (GO:0046209)3.95073357
43hypotonic response (GO:0006971)3.92440251
44regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.89067647
45artery smooth muscle contraction (GO:0014824)3.88238132
46morphogenesis of an epithelial fold (GO:0060571)3.85951210
47fucose catabolic process (GO:0019317)3.85900037
48L-fucose metabolic process (GO:0042354)3.85900037
49L-fucose catabolic process (GO:0042355)3.85900037
50positive regulation of lipid catabolic process (GO:0050996)3.82154728
51nucleotide-sugar biosynthetic process (GO:0009226)3.78093382
52sulfate transmembrane transport (GO:1902358)3.77883122
53regulation of cholesterol metabolic process (GO:0090181)3.77667144
54bicarbonate transport (GO:0015701)3.67403970
55regulation of vitamin metabolic process (GO:0030656)3.66797672
56regulation of systemic arterial blood pressure (GO:0003073)3.66397092
57artery development (GO:0060840)3.63390866
58vitamin transport (GO:0051180)3.61818363
59positive regulation of cGMP metabolic process (GO:0030825)3.61013338
60vitamin A metabolic process (GO:0006776)3.59504005
61regulation of cGMP metabolic process (GO:0030823)3.59049077
62UDP-N-acetylglucosamine metabolic process (GO:0006047)3.58512190
63urate metabolic process (GO:0046415)3.57391385
64positive regulation of interleukin-1 secretion (GO:0050716)3.54385761
65digestive system process (GO:0022600)3.52243801
66renal system process involved in regulation of blood volume (GO:0001977)3.51834146
67homocysteine metabolic process (GO:0050667)3.50429245
68phospholipid efflux (GO:0033700)3.50421109
69NADH metabolic process (GO:0006734)3.43481632
70intermediate filament organization (GO:0045109)3.40518935
71fucosylation (GO:0036065)3.39389813
72negative regulation of nitric-oxide synthase activity (GO:0051001)3.37927041
73glycerol metabolic process (GO:0006071)3.35933218
74pyrimidine ribonucleoside catabolic process (GO:0046133)3.33804083
75positive regulation of glycoprotein metabolic process (GO:1903020)3.32681079
76regulation of interleukin-1 secretion (GO:0050704)3.32040180
77cellular ketone body metabolic process (GO:0046950)3.31013167
78phosphatidylcholine biosynthetic process (GO:0006656)3.30941122
79intestinal epithelial cell development (GO:0060576)3.30643276
80xenobiotic catabolic process (GO:0042178)3.30392240
81negative regulation of protein tyrosine kinase activity (GO:0061099)3.30116824
82tonic smooth muscle contraction (GO:0014820)3.27981287
83ventricular cardiac muscle cell action potential (GO:0086005)3.26481517
84peptidyl-tyrosine autophosphorylation (GO:0038083)3.25028744
85viral transcription (GO:0019083)3.24732254
86adhesion of symbiont to host cell (GO:0044650)3.24680848
87virion attachment to host cell (GO:0019062)3.24680848
88alkaloid metabolic process (GO:0009820)3.22774893
89GDP-mannose metabolic process (GO:0019673)3.22655371
90sperm capacitation (GO:0048240)3.19190528
91digestion (GO:0007586)3.15986368
92positive regulation of triglyceride metabolic process (GO:0090208)3.13898206
93eosinophil chemotaxis (GO:0048245)3.13148135
94hormone catabolic process (GO:0042447)3.12881895
95negative regulation of keratinocyte proliferation (GO:0010839)3.11935456
96sulfate transport (GO:0008272)3.11019460
97positive regulation of pseudopodium assembly (GO:0031274)3.10281849
98receptor guanylyl cyclase signaling pathway (GO:0007168)3.09665605
99sodium ion homeostasis (GO:0055078)3.09002137
100diacylglycerol metabolic process (GO:0046339)3.08081669
101citrulline biosynthetic process (GO:0019240)3.07852796
102regulation of bile acid biosynthetic process (GO:0070857)3.03831380
103nitric oxide biosynthetic process (GO:0006809)3.03771865
104translational termination (GO:0006415)3.03597413
105positive regulation of glycoprotein biosynthetic process (GO:0010560)3.03346021
106sulfation (GO:0051923)3.02073979
107tight junction assembly (GO:0070830)3.01705380
108alditol metabolic process (GO:0019400)2.98154519
109hemidesmosome assembly (GO:0031581)2.95154267
110protein autoprocessing (GO:0016540)2.93686110
111positive regulation of fatty acid metabolic process (GO:0045923)2.93245902
112negative regulation of protein autophosphorylation (GO:0031953)2.91625380
113fucose metabolic process (GO:0006004)2.90625540
114prostanoid metabolic process (GO:0006692)2.90341449
115prostaglandin metabolic process (GO:0006693)2.90341449
116O-glycan processing (GO:0016266)2.90334110
117urea metabolic process (GO:0019627)2.90292915
118hepatocyte apoptotic process (GO:0097284)2.89796363
119regulation of histone phosphorylation (GO:0033127)2.89033020
120ethanol oxidation (GO:0006069)2.88667061
121oligosaccharide biosynthetic process (GO:0009312)2.88598057
122inositol phosphate-mediated signaling (GO:0048016)2.86108378
123triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.83312274
124regulation of metalloenzyme activity (GO:0048552)2.83171273
125transcytosis (GO:0045056)2.83169500
126regulation of cellular extravasation (GO:0002691)2.83131949
127cell communication involved in cardiac conduction (GO:0086065)2.83131811
128ketone body metabolic process (GO:1902224)2.82809467
129regulation of early endosome to late endosome transport (GO:2000641)2.81911642
130urea cycle (GO:0000050)2.81806284
131lipoprotein transport (GO:0042953)2.81618457
132negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.79260157
133eosinophil migration (GO:0072677)2.78982889
134very-low-density lipoprotein particle assembly (GO:0034379)2.78720198
135response to hepatocyte growth factor (GO:0035728)2.78425381
136cellular response to hepatocyte growth factor stimulus (GO:0035729)2.78425381
137regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.77935125
138quinone biosynthetic process (GO:1901663)2.75909063
139ubiquinone biosynthetic process (GO:0006744)2.75909063
140regulation of cell-cell adhesion mediated by cadherin (GO:2000047)2.75444390
141glycolipid catabolic process (GO:0019377)2.74907453
142regulation of respiratory burst (GO:0060263)2.74885493
143antibacterial humoral response (GO:0019731)2.73189143
144regulation of nitric-oxide synthase activity (GO:0050999)2.73045232
145drug transmembrane transport (GO:0006855)2.72757449
146drug metabolic process (GO:0017144)2.71022584
147negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.70781112
148regulation of cholesterol homeostasis (GO:2000188)2.70741903
149regulation of pseudopodium assembly (GO:0031272)2.70650952
150response to histamine (GO:0034776)2.70563421
151nucleoside diphosphate biosynthetic process (GO:0009133)2.70000244
152regulation of triglyceride catabolic process (GO:0010896)2.69860851
153DNA damage induced protein phosphorylation (GO:0006975)2.69813885
154positive regulation of Cdc42 GTPase activity (GO:0043089)2.68203762
155antimicrobial humoral response (GO:0019730)2.66745796
156thrombin receptor signaling pathway (GO:0070493)2.66204673
157cyclooxygenase pathway (GO:0019371)2.65931626
158regulation of RIG-I signaling pathway (GO:0039535)2.64270355
159SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.63476893
160protein targeting to ER (GO:0045047)2.63298608
161renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)2.62053645
162adhesion of symbiont to host (GO:0044406)2.61531987
163cotranslational protein targeting to membrane (GO:0006613)2.61493038
164positive regulation of triglyceride lipase activity (GO:0061365)2.60847643
165positive regulation of lipoprotein lipase activity (GO:0051006)2.60847643
166pyrimidine-containing compound transmembrane transport (GO:0072531)10.1363897

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.76980966
2TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.95009466
3CDX2_20551321_ChIP-Seq_CACO-2_Human3.67996283
4* SOX2_27498859_Chip-Seq_STOMACH_Mouse3.28450104
5HNF4A_19761587_ChIP-ChIP_CACO-2_Human3.28297481
6SRY_22984422_ChIP-ChIP_TESTIS_Rat3.21020338
7* SOX2_20726797_ChIP-Seq_SW620_Human3.10614986
8PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.97344438
9CDX2_19796622_ChIP-Seq_MESCs_Mouse2.91986000
10ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.86684355
11PPARA_22158963_ChIP-Seq_LIVER_Mouse2.82355157
12PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.71934046
13IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.55849148
14AR_21909140_ChIP-Seq_LNCAP_Human2.54410373
15* GATA6_25053715_ChIP-Seq_YYC3_Human2.43134130
16RXR_22158963_ChIP-Seq_LIVER_Mouse2.42959215
17* GATA4_25053715_ChIP-Seq_YYC3_Human2.20258104
18LXR_22158963_ChIP-Seq_LIVER_Mouse2.14036373
19* SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.11596951
20TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.95759681
21TCF4_18268006_ChIP-ChIP_LS174T_Human1.83611451
22RACK7_27058665_Chip-Seq_MCF-7_Human1.83418570
23IKZF1_21737484_ChIP-ChIP_HCT116_Human1.81274329
24TRIM28_21343339_ChIP-Seq_HEK293_Human1.80468457
25ESR2_21235772_ChIP-Seq_MCF-7_Human1.79296484
26KLF5_25053715_ChIP-Seq_YYC3_Human1.75978779
27FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.67283728
28ATF3_27146783_Chip-Seq_COLON_Human1.66106300
29KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.65253227
30P63_26484246_Chip-Seq_KERATINOCYTES_Human1.62781599
31RARG_19884340_ChIP-ChIP_MEFs_Mouse1.62001885
32CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.60408009
33PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.59624862
34KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.57956144
35RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57872478
36EGR1_23403033_ChIP-Seq_LIVER_Mouse1.57831685
37NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.56956815
38NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.52815746
39PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.52556980
40BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.52264267
41ESR1_21235772_ChIP-Seq_MCF-7_Human1.49958535
42FOXO3_23340844_ChIP-Seq_DLD1_Human1.47221649
43STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.44648652
44PPAR_26484153_Chip-Seq_NCI-H1993_Human1.44625681
45CLOCK_20551151_ChIP-Seq_293T_Human1.43164921
46UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.43061159
47TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.40463029
48ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.38303155
49SALL4_18804426_ChIP-ChIP_XEN_Mouse1.37058116
50CTCF_27219007_Chip-Seq_Bcells_Human1.35609951
51FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.35484216
52CREB1_26743006_Chip-Seq_LNCaP_Human1.34664061
53ELK1_22589737_ChIP-Seq_MCF10A_Human1.31974053
54TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.30251900
55BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.28894536
56CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.27448884
57* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.23337558
58NRF2_20460467_ChIP-Seq_MEFs_Mouse1.23104421
59NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.23104421
60RUNX1_27514584_Chip-Seq_MCF-7_Human1.22199892
61FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.19008050
62STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.17780915
63EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.17296727
64FOXM1_26456572_ChIP-Seq_MCF-7_Human1.16807820
65* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.14784183
66ZNF263_19887448_ChIP-Seq_K562_Human1.11776558
67KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.11377046
68* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.11209169
69* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.11209169
70KAP1_22055183_ChIP-Seq_ESCs_Mouse1.08245412
71CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.07917334
72TET1_21451524_ChIP-Seq_MESCs_Mouse1.05882731
73SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.04290731
74* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.04257721
75ZNF217_24962896_ChIP-Seq_MCF-7_Human1.02569549
76CJUN_26792858_Chip-Seq_BT549_Human1.01955905
77EGR1_19032775_ChIP-ChIP_M12_Human1.00847279
78OCT4_18692474_ChIP-Seq_MEFs_Mouse0.99785116
79TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.97796164
80LXR_22292898_ChIP-Seq_THP-1_Human0.97669036
81ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.96762053
82STAT6_21828071_ChIP-Seq_BEAS2B_Human0.95884966
83SMAD_19615063_ChIP-ChIP_OVARY_Human0.95089770
84ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.94293564
85CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.93542649
86GATA3_24758297_ChIP-Seq_MCF-7_Human0.93528217
87ELK3_25401928_ChIP-Seq_HUVEC_Human0.92897032
88NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.92624621
89* CDX2_22108803_ChIP-Seq_LS180_Human0.91534050
90SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.91348600
91TCF3_18692474_ChIP-Seq_MEFs_Mouse0.91312111
92IRF1_19129219_ChIP-ChIP_H3396_Human0.91145785
93NANOG_18692474_ChIP-Seq_MEFs_Mouse0.90923053
94TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.90782002
95GATA2_19941826_ChIP-Seq_K562_Human0.90347830
96CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89488851
97ERG_21242973_ChIP-ChIP_JURKAT_Human0.89452199
98POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88960719
99SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.88508546
100TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.88324029
101RAD21_21589869_ChIP-Seq_MESCs_Mouse0.87584148
102HNF4A_19822575_ChIP-Seq_HepG2_Human0.87152630
103TP63_22573176_ChIP-Seq_HFKS_Human0.86722249
104* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.86648843
105PHF8_20622854_ChIP-Seq_HELA_Human0.86457603
106FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.85971218
107CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.85794957
108EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.84874353
109NANOG_20526341_ChIP-Seq_ESCs_Human0.84595372
110BCL6_27268052_Chip-Seq_Bcells_Human0.84436958
111AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.84009417
112CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.83986078
113SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.83953566
114SOX2_18692474_ChIP-Seq_MEFs_Mouse0.83889890
115KLF4_18555785_ChIP-Seq_MESCs_Mouse0.83534933
116HTT_18923047_ChIP-ChIP_STHdh_Human0.82775962
117STAT1_20625510_ChIP-Seq_HELA_Human0.81804334
118ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.81787571
119GATA2_21666600_ChIP-Seq_HMVEC_Human0.81578984
120GATA1_26923725_Chip-Seq_HPCs_Mouse0.81473004
121HIF1A_21447827_ChIP-Seq_MCF-7_Human0.81332490
122ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.80927040
123SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.80282386
124P300_27268052_Chip-Seq_Bcells_Human0.79898510
125FOXA1_25552417_ChIP-Seq_VCAP_Human0.79708054
126* MYC_19915707_ChIP-ChIP_AK7_Human0.79075800
127SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.78872554
128AR_20517297_ChIP-Seq_VCAP_Human0.78290073
129BCOR_27268052_Chip-Seq_Bcells_Human0.78239735
130PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.78150214
131VDR_22108803_ChIP-Seq_LS180_Human0.77716403
132SMAD3_21741376_ChIP-Seq_HESCs_Human0.77128375

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005377_hearing/vestibular/ear_phenot4.47605165
2MP0003878_abnormal_ear_physiology4.47605165
3MP0002822_catalepsy4.42003381
4MP0001873_stomach_inflammation3.88540652
5MP0008004_abnormal_stomach_pH3.51459254
6MP0005360_urolithiasis3.36714482
7MP0001666_abnormal_nutrient_absorption3.17047656
8MP0003866_abnormal_defecation3.12478787
9MP0000462_abnormal_digestive_system2.82339709
10MP0001663_abnormal_digestive_system2.71544546
11MP0001664_abnormal_digestion2.65295345
12MP0008875_abnormal_xenobiotic_pharmacok2.61585399
13MP0005085_abnormal_gallbladder_physiolo2.59277493
14MP0005381_digestive/alimentary_phenotyp2.51108294
15MP0004264_abnormal_extraembryonic_tissu2.39861490
16MP0005257_abnormal_intraocular_pressure2.38274123
17MP0004147_increased_porphyrin_level2.25524917
18MP0005670_abnormal_white_adipose2.25410756
19MP0002139_abnormal_hepatobiliary_system2.25183004
20MP0003183_abnormal_peptide_metabolism2.24978463
21MP0003303_peritoneal_inflammation2.23234336
22MP0010678_abnormal_skin_adnexa2.03300505
23MP0010234_abnormal_vibrissa_follicle10.1424583
24MP0003252_abnormal_bile_duct1.82911437
25MP0005167_abnormal_blood-brain_barrier1.82546528
26MP0003300_gastrointestinal_ulcer1.81919781
27MP0000490_abnormal_crypts_of1.79122829
28MP0000477_abnormal_intestine_morphology1.78453348
29MP0003191_abnormal_cellular_cholesterol1.74078517
30MP0010155_abnormal_intestine_physiology1.67421238
31MP0003705_abnormal_hypodermis_morpholog1.66461415
32MP0002796_impaired_skin_barrier1.59630220
33MP0005367_renal/urinary_system_phenotyp1.55476486
34MP0000516_abnormal_urinary_system1.55476486
35MP0010329_abnormal_lipoprotein_level1.51663729
36MP0009785_altered_susceptibility_to1.47698771
37MP0003453_abnormal_keratinocyte_physiol1.46832203
38MP0000470_abnormal_stomach_morphology1.46421698
39MP0001756_abnormal_urination1.42366904
40MP0000383_abnormal_hair_follicle1.42273155
41MP0001764_abnormal_homeostasis1.33579557
42MP0001188_hyperpigmentation1.29955179
43MP0003806_abnormal_nucleotide_metabolis1.28920913
44MP0001501_abnormal_sleep_pattern1.28328722
45MP0009840_abnormal_foam_cell1.26900995
46MP0002132_abnormal_respiratory_system1.25226356
47MP0003941_abnormal_skin_development1.24856623
48MP0002876_abnormal_thyroid_physiology1.23698309
49MP0008872_abnormal_physiological_respon1.22681633
50MP0005408_hypopigmentation1.22500149
51MP0000685_abnormal_immune_system1.20269888
52MP0003868_abnormal_feces_composition1.16930892
53MP0004019_abnormal_vitamin_homeostasis1.13649951
54MP0003186_abnormal_redox_activity1.10926494
55MP0003315_abnormal_perineum_morphology1.09115416
56MP0002234_abnormal_pharynx_morphology1.09103416
57MP0004947_skin_inflammation1.06018276
58MP0005166_decreased_susceptibility_to1.05644770
59MP0002971_abnormal_brown_adipose1.05514302
60MP0003950_abnormal_plasma_membrane1.01399745
61MP0003879_abnormal_hair_cell1.00907868
62MP0002118_abnormal_lipid_homeostasis1.00886701
63MP0003693_abnormal_embryo_hatching0.94803481
64MP0006082_CNS_inflammation0.94212565
65MP0005165_increased_susceptibility_to0.93320291
66MP0000566_synostosis0.92749039
67MP0004885_abnormal_endolymph0.90685876
68MP0009643_abnormal_urine_homeostasis0.90677315
69MP0000230_abnormal_systemic_arterial0.88704449
70MP0003718_maternal_effect0.85237741
71MP0009333_abnormal_splenocyte_physiolog0.85149103
72MP0010352_gastrointestinal_tract_polyps0.85073466
73MP0002098_abnormal_vibrissa_morphology0.81405898
74MP0002060_abnormal_skin_morphology0.81018203
75MP0005501_abnormal_skin_physiology0.80602228
76MP0001216_abnormal_epidermal_layer0.78791620
77MP0008260_abnormal_autophagy0.78490331
78MP0005365_abnormal_bile_salt0.78293835
79MP0005084_abnormal_gallbladder_morpholo0.78213746
80MP0003385_abnormal_body_wall0.77613452
81MP0009115_abnormal_fat_cell0.76065825
82MP0000858_altered_metastatic_potential0.75679198
83MP0004043_abnormal_pH_regulation0.74398103
84MP0005076_abnormal_cell_differentiation0.73316245
85MP0001765_abnormal_ion_homeostasis0.73211533
86MP0000467_abnormal_esophagus_morphology0.72843286
87MP0005023_abnormal_wound_healing0.72796044
88MP0004185_abnormal_adipocyte_glucose0.72624438
89MP0009765_abnormal_xenobiotic_induced0.72381614
90MP0008873_increased_physiological_sensi0.72330673
91MP0005083_abnormal_biliary_tract0.69399795
92MP0003724_increased_susceptibility_to0.69356000
93MP0002896_abnormal_bone_mineralization0.68400330
94MP0002638_abnormal_pupillary_reflex0.68083229
95MP0002254_reproductive_system_inflammat0.67608455
96MP0010386_abnormal_urinary_bladder0.67228321
97MP0004782_abnormal_surfactant_physiolog0.66505514
98MP0001485_abnormal_pinna_reflex0.65996848
99MP0000249_abnormal_blood_vessel0.64622537
100MP0001849_ear_inflammation0.63660102
101MP0000613_abnormal_salivary_gland0.63085919
102MP0001881_abnormal_mammary_gland0.62953851
103MP0005058_abnormal_lysosome_morphology0.62894703
104MP0005666_abnormal_adipose_tissue0.60792239
105MP0000537_abnormal_urethra_morphology0.60704801
106MP0009379_abnormal_foot_pigmentation0.60548645
107MP0003283_abnormal_digestive_organ0.58921444
108MP0000609_abnormal_liver_physiology0.58276251
109MP0008469_abnormal_protein_level0.57217216
110MP0010771_integument_phenotype0.56650631
111MP0009384_cardiac_valve_regurgitation0.55183072
112MP0002138_abnormal_hepatobiliary_system0.54739785
113MP0005332_abnormal_amino_acid0.53879119
114MP0001879_abnormal_lymphatic_vessel0.53727330
115MP0000013_abnormal_adipose_tissue0.52983830
116MP0005636_abnormal_mineral_homeostasis0.52632189
117MP0005410_abnormal_fertilization0.52258006
118MP0009053_abnormal_anal_canal0.48817745
119MP0005025_abnormal_response_to0.47475745
120MP0003638_abnormal_response/metabolism_0.45599929
121MP0002136_abnormal_kidney_physiology0.44716120
122MP0000762_abnormal_tongue_morphology0.44463983
123MP0000678_abnormal_parathyroid_gland0.43838973
124MP0000003_abnormal_adipose_tissue0.41258960
125MP0009780_abnormal_chondrocyte_physiolo0.39702462
126MP0001440_abnormal_grooming_behavior0.39023716
127MP0005448_abnormal_energy_balance0.38285295
128MP0005584_abnormal_enzyme/coenzyme_acti0.38265646
129MP0005266_abnormal_metabolism0.37454467
130MP0000538_abnormal_urinary_bladder0.36377161
131MP0005319_abnormal_enzyme/_coenzyme0.36299455
132MP0001270_distended_abdomen0.35676023
133MP0009642_abnormal_blood_homeostasis0.34590192
134MP0001845_abnormal_inflammatory_respons0.34544813

Predicted human phenotypes

RankGene SetZ-score
1Malnutrition (HP:0004395)7.81547838
2Flat acetabular roof (HP:0003180)6.67703686
3Right ventricular cardiomyopathy (HP:0011663)6.63400805
4Abnormality of small intestinal villus morphology (HP:0011472)6.28449125
5Villous atrophy (HP:0011473)6.28449125
6Ileus (HP:0002595)5.28826808
7Pigmentary retinal degeneration (HP:0001146)5.19797170
8Abdominal distention (HP:0003270)4.90165671
9Cupped ribs (HP:0000887)4.68123632
10Abnormal tarsal ossification (HP:0008369)4.62758744
11Prostate neoplasm (HP:0100787)4.46229866
12Woolly hair (HP:0002224)4.34616127
13Gout (HP:0001997)4.20012557
14Hyperactive renin-angiotensin system (HP:0000841)4.11112224
15Chorioretinal atrophy (HP:0000533)4.09207439
16Oligomenorrhea (HP:0000876)3.78920659
17Pustule (HP:0200039)3.78846223
18Fragile nails (HP:0001808)3.55426358
19Alopecia of scalp (HP:0002293)3.55166405
20Vascular calcification (HP:0004934)3.50898983
21Abnormality of chloride homeostasis (HP:0011422)3.36591678
22Congenital sensorineural hearing impairment (HP:0008527)3.31092133
23Dehydration (HP:0001944)3.26811538
24Xanthomatosis (HP:0000991)3.23226944
25Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.20581804
26Steatorrhea (HP:0002570)3.20245513
27Hypoalphalipoproteinemia (HP:0003233)3.19194425
28Abnormal foot bone ossification (HP:0010675)3.15082668
29Decreased circulating renin level (HP:0003351)3.14961581
30Metabolic alkalosis (HP:0200114)3.11343517
31Intrahepatic cholestasis (HP:0001406)3.00367316
32Hypolipoproteinemia (HP:0010981)2.99145575
33Cardiovascular calcification (HP:0011915)2.96390642
34Hyperlipoproteinemia (HP:0010980)2.89445373
35Hyperammonemia (HP:0001987)2.89012367
36Palpitations (HP:0001962)2.87711634
37Hyperglycinuria (HP:0003108)2.79789520
38Abnormality of the vitamin B12 metabolism (HP:0004341)2.78137311
39Hypoglycemic coma (HP:0001325)2.77295329
40Macrocytic anemia (HP:0001972)2.76737006
41Segmental peripheral demyelination/remyelination (HP:0003481)2.75580225
42Congenital stationary night blindness (HP:0007642)2.67518227
43Facial shape deformation (HP:0011334)2.67357923
44Potter facies (HP:0002009)2.67357923
45Focal segmental glomerulosclerosis (HP:0000097)2.63237785
46Decreased electroretinogram (ERG) amplitude (HP:0000654)2.63169555
47Abnormality of fatty-acid metabolism (HP:0004359)2.60976041
48Abnormal biliary tract morphology (HP:0012440)2.60329621
49Abnormality of glutamine family amino acid metabolism (HP:0010902)2.57934932
50Abnormality of vitamin B metabolism (HP:0004340)2.56883806
51Curly hair (HP:0002212)2.55943121
52Stenosis of the external auditory canal (HP:0000402)2.54745755
53Abnormality of carpal bone ossification (HP:0006257)2.54525496
54Abnormality of serine family amino acid metabolism (HP:0010894)2.51833558
55Abnormality of glycine metabolism (HP:0010895)2.51833558
56Hypobetalipoproteinemia (HP:0003563)2.51505065
57Gastrointestinal dysmotility (HP:0002579)2.51298802
58Confusion (HP:0001289)2.51266747
59Abnormality of nucleobase metabolism (HP:0010932)2.47974251
60Widely patent fontanelles and sutures (HP:0004492)2.46674892
61Acanthocytosis (HP:0001927)2.46575786
62Ventricular tachycardia (HP:0004756)2.45006622
63Abnormality of the distal phalanges of the toes (HP:0010182)2.42348447
64Congenital, generalized hypertrichosis (HP:0004540)2.39216181
65Hypophosphatemic rickets (HP:0004912)2.38687606
66Alveolar cell carcinoma (HP:0006519)2.37637797
67Milia (HP:0001056)2.36025478
68Nephrolithiasis (HP:0000787)2.35985887
69Micronodular cirrhosis (HP:0001413)2.32766771
70Hemorrhage of the eye (HP:0011885)2.30480467
71Biliary tract neoplasm (HP:0100574)2.25722689
72Hyperglycinemia (HP:0002154)2.25617132
73Abnormality of the gastric mucosa (HP:0004295)2.24682379
74Cheilitis (HP:0100825)2.24439657
75Toxemia of pregnancy (HP:0100603)2.23786995
76Abnormality of monocarboxylic acid metabolism (HP:0010996)2.23283275
77Pendular nystagmus (HP:0012043)2.23034590
78Renal tubular acidosis (HP:0001947)2.22815796
79Posterior subcapsular cataract (HP:0007787)2.20026199
80Chronic diarrhea (HP:0002028)2.19811116
81Thin bony cortex (HP:0002753)2.17982041
82Hyponatremia (HP:0002902)2.17845529
83Cerebral palsy (HP:0100021)2.17306585
84Achilles tendon contracture (HP:0001771)2.17172921
85Pili torti (HP:0003777)2.15949755
86Abnormality of the costochondral junction (HP:0000919)2.14381665
87Rhabdomyolysis (HP:0003201)2.14323431
88Abnormality of the Achilles tendon (HP:0005109)2.09854231
89Metabolic acidosis (HP:0001942)2.09798689
90Hepatic necrosis (HP:0002605)2.09419949
91Vacuolated lymphocytes (HP:0001922)2.09392228
92Polygenic inheritance (HP:0010982)2.08936327
93Glomerulosclerosis (HP:0000096)2.08559315
94Parakeratosis (HP:0001036)2.05394560
95Hydroxyprolinuria (HP:0003080)2.05375779
96Abnormality of proline metabolism (HP:0010907)2.05375779
97Abnormality of aromatic amino acid family metabolism (HP:0004338)2.04161336
98Symphalangism affecting the phalanges of the hand (HP:0009773)2.04064972
99Plantar hyperkeratosis (HP:0007556)2.03778257
100Neoplasm of the tracheobronchial system (HP:0100552)2.01729730
101Hypercholesterolemia (HP:0003124)2.01682756
102Abnormality of purine metabolism (HP:0004352)2.01309425
103Amelogenesis imperfecta (HP:0000705)2.01221998
104Difficulty running (HP:0009046)2.00908942
105Mildly elevated creatine phosphokinase (HP:0008180)2.00898617
106Protuberant abdomen (HP:0001538)2.00384174
107Hyperphosphaturia (HP:0003109)1.99638614
108Lethargy (HP:0001254)1.99130995
109Conjugated hyperbilirubinemia (HP:0002908)1.99118277
110Abnormality of vitamin metabolism (HP:0100508)1.98986614
111Syncope (HP:0001279)1.98775965
112Dicarboxylic aciduria (HP:0003215)1.98668119
113Abnormality of dicarboxylic acid metabolism (HP:0010995)1.98668119
114Esophageal varix (HP:0002040)1.98664770
115Abnormality of renin-angiotensin system (HP:0000847)1.97652766
116Ridged nail (HP:0001807)1.97062066
117Type I diabetes mellitus (HP:0100651)1.96603634
118Exocrine pancreatic insufficiency (HP:0001738)1.96177738
119Fat malabsorption (HP:0002630)1.96088984
120Fragile skin (HP:0001030)1.96003027
121Increased purine levels (HP:0004368)1.95877524
122Hyperuricemia (HP:0002149)1.95877524
123Metaphyseal irregularity (HP:0003025)1.95149484
124Hepatocellular necrosis (HP:0001404)1.94896460
125Congenital ichthyosiform erythroderma (HP:0007431)1.94562933
126Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.93733336
127Pterygium (HP:0001059)1.93100134
128Proximal tubulopathy (HP:0000114)1.91953590
129Sensorimotor neuropathy (HP:0007141)1.90602758
130Hyperglycemia (HP:0003074)1.89955389
131Atrophic scars (HP:0001075)1.89942579
132Paraparesis (HP:0002385)1.88992577
133Subcapsular cataract (HP:0000523)1.88123018
134Alkalosis (HP:0001948)1.87997029
135Termporal pattern (HP:0011008)1.87410244
136Insidious onset (HP:0003587)1.87410244
137Shawl scrotum (HP:0000049)1.87249569
138Generalized aminoaciduria (HP:0002909)1.86810408
139Hyperaldosteronism (HP:0000859)1.86335850
140Hyperphosphatemia (HP:0002905)1.86234827
141Petechiae (HP:0000967)1.86096763
142Abnormal ossification of hand bones (HP:0005921)1.86096572
143Palmar hyperkeratosis (HP:0010765)1.85917639
144Pancreatitis (HP:0001733)1.84605641
145Abnormal urine phosphate concentration (HP:0012599)1.82635617
146Neoplasm of the rectum (HP:0100743)1.82298076
147Ventricular arrhythmia (HP:0004308)1.81628736
148Progressive sensorineural hearing impairment (HP:0000408)1.81197967
149Myoglobinuria (HP:0002913)1.81060191
150Ventricular fibrillation (HP:0001663)1.80859764
151Glycosuria (HP:0003076)1.77225162
152Abnormality of urine glucose concentration (HP:0011016)1.77225162
153Abnormal hand bone ossification (HP:0010660)1.76160763
154Abnormality of the prostate (HP:0008775)1.75153402
155Nausea (HP:0002018)1.73692428

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PIK3CA8.14172809
2MST1R7.92383626
3MAP3K24.42268939
4LMTK23.93604046
5KSR23.63177632
6MAP2K23.53204934
7ACVR1B3.11133451
8MET2.86166190
9EPHB22.72666765
10PRKG22.27717923
11MYLK2.18025813
12STK242.04570255
13MST41.91162866
14NME11.89787878
15PBK1.87906768
16NEK11.73815532
17TTK1.65626434
18MAP2K11.63120773
19OXSR11.58116924
20CAMK2D1.52222065
21GRK11.49795649
22FRK1.48132291
23TESK11.47644825
24EPHA21.40410205
25PDK21.40387345
26TESK21.38748588
27PAK41.33951463
28MAP3K31.29456805
29ERBB41.16668092
30ADRBK21.06034615
31TYK21.04111408
32MAP3K11.02799898
33GRK60.97472014
34SIK10.93573593
35NME20.92633785
36MAP3K80.87931914
37AKT30.86969111
38TAOK30.86774611
39RIPK40.85510629
40EIF2AK10.85509803
41CDK190.83643272
42DMPK0.80861769
43RPS6KB20.79302523
44DDR20.76242361
45ADRBK10.71772183
46BRSK20.69420722
47LIMK10.67954142
48NUAK10.67188855
49BRAF0.65755118
50PKN20.65680919
51ABL20.65148029
52TRIB30.64934442
53RET0.64664049
54EPHB10.64083622
55STK38L0.63790161
56MATK0.63008431
57ARAF0.60065982
58PDPK10.59766830
59PTK60.59449175
60CLK10.59258456
61MAP3K140.58833663
62IRAK30.58590763
63MAPKAPK20.57715184
64CAMK2G0.57464747
65EIF2AK30.57402100
66WNK10.55330310
67CAMK2B0.54871563
68DAPK30.54297467
69PRKD30.52746440
70PRKCI0.51856314
71TIE10.49820296
72BMX0.47689156
73CDK90.45861451
74PTK20.45781197
75EEF2K0.45741058
76FER0.42124995
77BCKDK0.40940338
78LRRK20.40848732
79RIPK10.39999467
80TAOK10.39930001
81MAP3K90.39850067
82PAK20.39322079
83SRC0.37400467
84ILK0.37096946
85MAPK150.37096545
86CSK0.36715659
87ALK0.36370807
88STK30.35547435
89TBK10.35114285
90MAP3K110.35074206
91PIK3CG0.34543000
92BCR0.33999942
93EPHA30.33518265
94DAPK10.31741761
95PDK10.31154303
96STK100.30649919
97MAP3K120.30350797
98PTK2B0.29846683
99PRKCA0.29531474
100ROCK10.28030186
101AURKB0.25084044
102CDK80.24430541
103MELK0.24236916
104ERN10.22767266
105TAOK20.22558809
106ITK0.22324027
107PAK10.21822427
108GSK3A0.21504404
109SIK30.20367138
110PRKD20.19887963
111MAP3K130.19720000
112JAK20.19604610
113PIM20.19600009
114MAPK40.19559240
115STK390.19556537
116FYN0.19414057
117ERBB20.19108937
118BUB10.19014676
119CDK30.17794437
120IGF1R0.17353375
121CDC42BPA0.17255347
122CSNK1E0.16771289
123MAP3K100.15940758
124PRKCQ0.15471896
125GRK50.14571486
126DYRK30.13213319
127KDR0.12580208
128PRKACG0.12240036
129MAP2K60.11393394
130LYN0.10932688
131RPS6KA50.10733277
132PRKCB0.10324672
133CSNK2A20.10159965
134MAPK70.10157821
135PRKCH0.09825713
136TTN0.09724939
137PRKCE0.09548556
138PRKAA20.07230111
139TNIK0.07213190
140FGFR40.07078618
141CSNK1A10.06243896
142PRKCD0.06199207
143CAMK2A0.05159444

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009205.75923494
2Mineral absorption_Homo sapiens_hsa049784.14837376
3Cyanoamino acid metabolism_Homo sapiens_hsa004604.05622576
4Fat digestion and absorption_Homo sapiens_hsa049753.57665808
5Bile secretion_Homo sapiens_hsa049762.57222591
6Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.54094537
7Sulfur relay system_Homo sapiens_hsa041222.35769702
8Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.33586651
9Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.31053331
10Histidine metabolism_Homo sapiens_hsa003402.20441920
11Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.12664266
12Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008602.05871345
13Galactose metabolism_Homo sapiens_hsa000521.89820245
14Chemical carcinogenesis_Homo sapiens_hsa052041.89742749
15Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.79487323
16Vitamin digestion and absorption_Homo sapiens_hsa049771.76644912
17Ribosome_Homo sapiens_hsa030101.68814168
18Renin-angiotensin system_Homo sapiens_hsa046141.65815279
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.64513093
20Phenylalanine metabolism_Homo sapiens_hsa003601.53029234
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.52452155
22Fatty acid degradation_Homo sapiens_hsa000711.50267624
23Oxidative phosphorylation_Homo sapiens_hsa001901.49035290
24PPAR signaling pathway_Homo sapiens_hsa033201.44502602
25Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.43739079
26Maturity onset diabetes of the young_Homo sapiens_hsa049501.42185747
27Intestinal immune network for IgA production_Homo sapiens_hsa046721.38431983
28Pentose and glucuronate interconversions_Homo sapiens_hsa000401.35936707
29Starch and sucrose metabolism_Homo sapiens_hsa005001.33544492
30Bladder cancer_Homo sapiens_hsa052191.29232230
31Glutathione metabolism_Homo sapiens_hsa004801.29093479
32Folate biosynthesis_Homo sapiens_hsa007901.26116060
33Butanoate metabolism_Homo sapiens_hsa006501.24858104
34Fructose and mannose metabolism_Homo sapiens_hsa000511.24566355
35Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.23784194
36Thyroid cancer_Homo sapiens_hsa052161.22525891
37Caffeine metabolism_Homo sapiens_hsa002321.20735514
38alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.17237982
39Tight junction_Homo sapiens_hsa045301.11907885
40Glycerolipid metabolism_Homo sapiens_hsa005611.10330125
41Gastric acid secretion_Homo sapiens_hsa049711.10187185
42Tryptophan metabolism_Homo sapiens_hsa003801.08653374
43Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.08541955
44Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.08487901
45Carbohydrate digestion and absorption_Homo sapiens_hsa049731.04789047
46Parkinsons disease_Homo sapiens_hsa050121.03211920
47beta-Alanine metabolism_Homo sapiens_hsa004101.02344145
48Pancreatic secretion_Homo sapiens_hsa049721.00675983
49Fatty acid biosynthesis_Homo sapiens_hsa000610.99998105
50Alzheimers disease_Homo sapiens_hsa050100.99784510
51Linoleic acid metabolism_Homo sapiens_hsa005910.98822959
52Protein digestion and absorption_Homo sapiens_hsa049740.95985242
53Salivary secretion_Homo sapiens_hsa049700.92998410
54Steroid hormone biosynthesis_Homo sapiens_hsa001400.89675819
55ABC transporters_Homo sapiens_hsa020100.89002844
56Nitrogen metabolism_Homo sapiens_hsa009100.88372685
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.85646249
58Other glycan degradation_Homo sapiens_hsa005110.85608252
59Proteasome_Homo sapiens_hsa030500.83432154
60Cardiac muscle contraction_Homo sapiens_hsa042600.76104075
61Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.74656153
62Glycerophospholipid metabolism_Homo sapiens_hsa005640.73322095
63Sphingolipid metabolism_Homo sapiens_hsa006000.72866789
64Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.72478739
65Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.71053185
66Drug metabolism - other enzymes_Homo sapiens_hsa009830.70557561
67Arginine biosynthesis_Homo sapiens_hsa002200.70183261
68Leukocyte transendothelial migration_Homo sapiens_hsa046700.69531645
69Hepatitis C_Homo sapiens_hsa051600.67334878
70Fatty acid metabolism_Homo sapiens_hsa012120.66971781
71Pyruvate metabolism_Homo sapiens_hsa006200.65572035
72Dorso-ventral axis formation_Homo sapiens_hsa043200.64530839
73Primary bile acid biosynthesis_Homo sapiens_hsa001200.62831792
74Tyrosine metabolism_Homo sapiens_hsa003500.61189863
75Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.60799923
76Pentose phosphate pathway_Homo sapiens_hsa000300.59648020
77Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.58165220
78Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.57012847
79Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.55953212
80HIF-1 signaling pathway_Homo sapiens_hsa040660.55101315
81Retinol metabolism_Homo sapiens_hsa008300.53245576
82Biosynthesis of amino acids_Homo sapiens_hsa012300.51702853
83Salmonella infection_Homo sapiens_hsa051320.49301955
84Type II diabetes mellitus_Homo sapiens_hsa049300.47115350
85Huntingtons disease_Homo sapiens_hsa050160.46579632
86Propanoate metabolism_Homo sapiens_hsa006400.45609065
87Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.43259666
88Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.43030735
89Cysteine and methionine metabolism_Homo sapiens_hsa002700.40599881
90Adherens junction_Homo sapiens_hsa045200.40180859
91Gap junction_Homo sapiens_hsa045400.38966131
92Fatty acid elongation_Homo sapiens_hsa000620.38811834
93Arachidonic acid metabolism_Homo sapiens_hsa005900.37446063
94Prion diseases_Homo sapiens_hsa050200.36914999
95Ether lipid metabolism_Homo sapiens_hsa005650.36640454
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.34460718
97African trypanosomiasis_Homo sapiens_hsa051430.34143300
98Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.32712890
99Carbon metabolism_Homo sapiens_hsa012000.30628458
100Central carbon metabolism in cancer_Homo sapiens_hsa052300.29904350
101Complement and coagulation cascades_Homo sapiens_hsa046100.27259592
102Metabolic pathways_Homo sapiens_hsa011000.27252657
103Vascular smooth muscle contraction_Homo sapiens_hsa042700.25988515
104Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.25272494
105Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.25013133
106Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.24359969
107Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.22242775
108Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.22070578
109Thyroid hormone synthesis_Homo sapiens_hsa049180.21367312
110Peroxisome_Homo sapiens_hsa041460.19327427
111NOD-like receptor signaling pathway_Homo sapiens_hsa046210.18333465
112GnRH signaling pathway_Homo sapiens_hsa049120.16498484
113Selenocompound metabolism_Homo sapiens_hsa004500.16182927
114Glycosaminoglycan degradation_Homo sapiens_hsa005310.14698552
115Long-term depression_Homo sapiens_hsa047300.13660321
1162-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.13531279
117Pertussis_Homo sapiens_hsa051330.13240316
118Arginine and proline metabolism_Homo sapiens_hsa003300.12559163
119Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.11713295
120Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.10667863
121Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.09166714
122Inositol phosphate metabolism_Homo sapiens_hsa005620.07171243
123Phototransduction_Homo sapiens_hsa047440.07002551
124SNARE interactions in vesicular transport_Homo sapiens_hsa041300.01061303

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