ARL5B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and ARFs are part of the RAS superfamily of regulatory GTPases. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1embryonic process involved in female pregnancy (GO:0060136)4.41446675
2pyrimidine nucleobase catabolic process (GO:0006208)4.14406697
3lateral sprouting from an epithelium (GO:0060601)4.03446660
4mitotic sister chromatid cohesion (GO:0007064)4.00864743
5nuclear pore complex assembly (GO:0051292)3.94480530
6pre-miRNA processing (GO:0031054)3.84627071
7regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.81829809
8midgut development (GO:0007494)3.75665534
9dopaminergic neuron differentiation (GO:0071542)3.73669568
10regulation of nucleobase-containing compound transport (GO:0032239)3.65644623
11nuclear pore organization (GO:0006999)3.58116195
12mitotic chromosome condensation (GO:0007076)3.55589195
13cytoplasmic mRNA processing body assembly (GO:0033962)3.53622464
14cellular protein complex localization (GO:0034629)3.52538056
15hippo signaling (GO:0035329)3.49098085
16cell migration involved in sprouting angiogenesis (GO:0002042)3.48189301
17paraxial mesoderm development (GO:0048339)3.43853599
18DNA unwinding involved in DNA replication (GO:0006268)3.42384108
19embryonic foregut morphogenesis (GO:0048617)3.42182138
20protein localization to chromosome, centromeric region (GO:0071459)3.40883377
21protein localization to kinetochore (GO:0034501)3.40077833
22regulation of histone H3-K9 methylation (GO:0051570)3.39329233
23negative regulation of DNA repair (GO:0045738)3.36867284
24regulation of NFAT protein import into nucleus (GO:0051532)3.35355697
25protein complex localization (GO:0031503)3.33296218
26nucleobase catabolic process (GO:0046113)3.25401850
27G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.19421040
28heterochromatin organization (GO:0070828)3.15642190
29establishment of tissue polarity (GO:0007164)3.11118460
30establishment of planar polarity (GO:0001736)3.11118460
31gastrulation with mouth forming second (GO:0001702)3.10899314
32sister chromatid segregation (GO:0000819)3.04907965
33planar cell polarity pathway involved in neural tube closure (GO:0090179)3.02930135
34endocardial cushion morphogenesis (GO:0003203)3.02030444
35regulation of sister chromatid cohesion (GO:0007063)3.01744300
36radial glial cell differentiation (GO:0060019)3.01553563
37positive regulation of cell cycle checkpoint (GO:1901978)3.01268542
38nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)3.00278401
39trophectodermal cell differentiation (GO:0001829)2.99860629
40neuronal stem cell maintenance (GO:0097150)2.97801840
41regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.92020325
42dosage compensation (GO:0007549)2.91810810
43face development (GO:0060324)2.90657383
44notochord development (GO:0030903)2.88375735
45morphogenesis of an epithelial sheet (GO:0002011)2.86843590
46trophoblast giant cell differentiation (GO:0060707)2.86586273
47RNA stabilization (GO:0043489)2.86540543
48mRNA stabilization (GO:0048255)2.86540543
49mitotic G2/M transition checkpoint (GO:0044818)2.84850453
50regulation of cytokine secretion involved in immune response (GO:0002739)2.84701065
51regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.82434379
52regulation of transforming growth factor beta2 production (GO:0032909)2.82008869
53positive regulation of catenin import into nucleus (GO:0035413)2.81551065
54mesenchyme morphogenesis (GO:0072132)2.80321053
55mitotic G2 DNA damage checkpoint (GO:0007095)2.79786106
56ectodermal placode formation (GO:0060788)2.79468166
57cell surface receptor signaling pathway involved in heart development (GO:0061311)2.77319223
58endothelial cell chemotaxis (GO:0035767)2.76925926
59negative regulation of cholesterol transport (GO:0032375)2.76752889
60negative regulation of sterol transport (GO:0032372)2.76752889
61regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.76205981
62DNA topological change (GO:0006265)2.76090123
63axon extension involved in axon guidance (GO:0048846)2.75474693
64neuron projection extension involved in neuron projection guidance (GO:1902284)2.75474693
65regulation of heart morphogenesis (GO:2000826)2.75128805
66negative regulation of NF-kappaB import into nucleus (GO:0042347)2.73417569
67positive regulation of SMAD protein import into nucleus (GO:0060391)2.72981403
68DNA duplex unwinding (GO:0032508)2.71764312
69positive regulation of fatty acid beta-oxidation (GO:0032000)2.71749293
70dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.71234323
71regulation of helicase activity (GO:0051095)2.70206085
72pore complex assembly (GO:0046931)2.70163949
73NLS-bearing protein import into nucleus (GO:0006607)2.68903241
74positive regulation of DNA-templated transcription, initiation (GO:2000144)2.68364085
75regulation of centriole replication (GO:0046599)2.67830329
76regulation of stem cell maintenance (GO:2000036)2.66988869
77non-recombinational repair (GO:0000726)2.66986987
78double-strand break repair via nonhomologous end joining (GO:0006303)2.66986987
79cell proliferation involved in kidney development (GO:0072111)2.66784144
80regulation of cardioblast differentiation (GO:0051890)2.66664165
81artery development (GO:0060840)2.66453472
82DNA geometric change (GO:0032392)2.65378843
83negative regulation of axon extension involved in axon guidance (GO:0048843)2.64871086
84mitotic metaphase plate congression (GO:0007080)2.63392360
85branching involved in labyrinthine layer morphogenesis (GO:0060670)2.62822732
86metaphase plate congression (GO:0051310)2.62235573
87regulation of cell proliferation involved in heart morphogenesis (GO:2000136)2.61922856
88lung lobe morphogenesis (GO:0060463)2.61328164
89positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.60710689
90negative regulation of translation, ncRNA-mediated (GO:0040033)2.58973054
91regulation of translation, ncRNA-mediated (GO:0045974)2.58973054
92negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.58973054
93regulation of fever generation (GO:0031620)2.58877536
94regulation of DNA damage checkpoint (GO:2000001)2.58820525
95positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.58472982
96epithelial cell differentiation involved in prostate gland development (GO:0060742)2.57797639
97stress granule assembly (GO:0034063)2.57054869
98regulation of RNA export from nucleus (GO:0046831)2.56082330
99dorsal/ventral axis specification (GO:0009950)2.55734724
100positive regulation of astrocyte differentiation (GO:0048711)2.54936666
101regulation of gene silencing by RNA (GO:0060966)2.53947315
102regulation of posttranscriptional gene silencing (GO:0060147)2.53947315
103regulation of gene silencing by miRNA (GO:0060964)2.53947315
104negative regulation of fibrinolysis (GO:0051918)2.53151482
105bundle of His cell to Purkinje myocyte communication (GO:0086069)2.52416706
106response to UV-C (GO:0010225)2.50916544
107chondrocyte development (GO:0002063)2.49648150
108mitotic nuclear envelope disassembly (GO:0007077)2.48072392
109mitotic sister chromatid segregation (GO:0000070)2.47751282
110regulation of gamma-delta T cell differentiation (GO:0045586)2.47220958
111histone lysine demethylation (GO:0070076)2.47200633
112regulation of transforming growth factor beta production (GO:0071634)2.46510841
113regulation of chromatin silencing (GO:0031935)2.46045080
114regulation of chromosome segregation (GO:0051983)2.45377716
115nuclear envelope disassembly (GO:0051081)2.45194302
116membrane disassembly (GO:0030397)2.45194302
117urea cycle (GO:0000050)2.45109185
118urea metabolic process (GO:0019627)2.45109185
119germ cell migration (GO:0008354)2.44980788
120anterior/posterior axis specification, embryo (GO:0008595)2.44777028
121regulation of mitotic metaphase/anaphase transition (GO:0030071)2.44013241
122regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.44013241
123establishment of nucleus localization (GO:0040023)2.43594453
124epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.43504365
125negative regulation of chromosome segregation (GO:0051985)2.42567096
126negative regulation of mitotic sister chromatid segregation (GO:0033048)2.42311532
127negative regulation of mitotic sister chromatid separation (GO:2000816)2.42311532
128negative regulation of sister chromatid segregation (GO:0033046)2.42311532
129negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.42311532
130negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.42311532
131regulation of cardioblast proliferation (GO:0003264)2.41918921
132regulation of secondary heart field cardioblast proliferation (GO:0003266)2.41918921
133regulation of interleukin-12 biosynthetic process (GO:0045075)2.41686523
134negative regulation of axon guidance (GO:1902668)2.41093124
135central nervous system projection neuron axonogenesis (GO:0021952)2.40058874
136embryonic retina morphogenesis in camera-type eye (GO:0060059)2.39494929
137negative regulation of catenin import into nucleus (GO:0035414)2.39413180
138regulation of mitotic sister chromatid separation (GO:0010965)2.38993793
139regulation of mitotic sister chromatid segregation (GO:0033047)2.38993793
140regulation of sister chromatid segregation (GO:0033045)2.38993793
141establishment of integrated proviral latency (GO:0075713)2.38681341
142primitive streak formation (GO:0090009)2.38423693
143regulation of cell-cell adhesion mediated by cadherin (GO:2000047)2.38270433
144regulation of DNA-templated transcription, initiation (GO:2000142)2.37823748
145embryonic camera-type eye morphogenesis (GO:0048596)2.37291234
146positive regulation of cell size (GO:0045793)2.37155859
147blood vessel endothelial cell migration (GO:0043534)2.36978208
148regulation of non-canonical Wnt signaling pathway (GO:2000050)2.36907429
149regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.36246373
150cell proliferation involved in metanephros development (GO:0072203)2.36114364
151histone demethylation (GO:0016577)2.36057937
152regulation of fibrinolysis (GO:0051917)2.35798802
153regulation of gamma-delta T cell activation (GO:0046643)2.35631793
154negative regulation of fibroblast apoptotic process (GO:2000270)2.34899206
155regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.33912654
156regulation of mesenchymal cell proliferation (GO:0010464)2.31884439
157negative regulation of oligodendrocyte differentiation (GO:0048715)2.31117491
158positive regulation of mesenchymal cell proliferation (GO:0002053)2.26673534
159negative regulation of histone methylation (GO:0031061)2.24643797
160regulation of p38MAPK cascade (GO:1900744)2.20935404
161mesenchymal cell proliferation (GO:0010463)2.20269687
162lung epithelium development (GO:0060428)2.19685043
163regulation of catenin import into nucleus (GO:0035412)2.18599379
164post-anal tail morphogenesis (GO:0036342)2.18575138
165insulin-like growth factor receptor signaling pathway (GO:0048009)2.17594353
166limb bud formation (GO:0060174)2.16326405
167regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.15985239
168interkinetic nuclear migration (GO:0022027)2.14894588
169cochlea morphogenesis (GO:0090103)2.14594804
170positive regulation of hormone biosynthetic process (GO:0046886)2.13998502
171positive regulation of p38MAPK cascade (GO:1900745)2.13962912
172somite development (GO:0061053)2.13651965
173positive regulation of BMP signaling pathway (GO:0030513)2.12183093
174monoubiquitinated protein deubiquitination (GO:0035520)2.11896533

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EGR1_19374776_ChIP-ChIP_THP-1_Human4.33748545
2SALL1_21062744_ChIP-ChIP_HESCs_Human4.25845007
3TP63_17297297_ChIP-ChIP_HaCaT_Human4.15938067
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.07365216
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.76139031
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.59474148
7STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse3.15251395
8FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.12149389
9TP63_19390658_ChIP-ChIP_HaCaT_Human2.89162117
10AR_21909140_ChIP-Seq_LNCAP_Human2.83649244
11CLOCK_20551151_ChIP-Seq_293T_Human2.78602649
12E2F7_22180533_ChIP-Seq_HELA_Human2.73642432
13CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.51373568
14FOXM1_23109430_ChIP-Seq_U2OS_Human2.43611066
15RBPJ_22232070_ChIP-Seq_NCS_Mouse2.40405376
16WT1_19549856_ChIP-ChIP_CCG9911_Human2.25254880
17NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.19707917
18TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.14943046
19PRDM5_23873026_ChIP-Seq_MEFs_Mouse2.12792951
20ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.99985799
21FUS_26573619_Chip-Seq_HEK293_Human1.98802106
22* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.95599568
23TRIM28_21343339_ChIP-Seq_HEK293_Human1.94940855
24* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.92896290
25HIF1A_21447827_ChIP-Seq_MCF-7_Human1.88201490
26TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.88113174
27BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.88034887
28FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.85339532
29STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.82287165
30ESR1_21235772_ChIP-Seq_MCF-7_Human1.80822788
31SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.80253318
32LXR_22158963_ChIP-Seq_LIVER_Mouse1.71918703
33POU3F2_20337985_ChIP-ChIP_501MEL_Human1.71536185
34RXR_22158963_ChIP-Seq_LIVER_Mouse1.69911835
35FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.68313658
36STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.66998464
37EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.64046286
38WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.61994341
39E2F1_21310950_ChIP-Seq_MCF-7_Human1.56727824
40ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.50498383
41HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.50207161
42EGR1_23403033_ChIP-Seq_LIVER_Mouse1.46718330
43PKCTHETA_26484144_Chip-Seq_BREAST_Human1.42641249
44PPARA_22158963_ChIP-Seq_LIVER_Mouse1.42283686
45SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.41673387
46CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.41177982
47SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.41034372
48ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.40898962
49ISL1_27105846_Chip-Seq_CPCs_Mouse1.35105181
50* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.34202576
51ZFP281_27345836_Chip-Seq_ESCs_Mouse1.33282368
52NFIB_24661679_ChIP-Seq_LUNG_Mouse1.32556600
53SALL4_18804426_ChIP-ChIP_XEN_Mouse1.32363056
54CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.31938253
55SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.31885420
56SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.31885420
57BRD4_25478319_ChIP-Seq_HGPS_Human1.29256659
58* FOXO3_23340844_ChIP-Seq_DLD1_Human1.26906371
59MYC_18555785_ChIP-Seq_MESCs_Mouse1.25567866
60RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.25430839
61TCF4_18268006_ChIP-ChIP_LS174T_Human1.24930693
62* ELK1_19687146_ChIP-ChIP_HELA_Human1.23511156
63RING1B_27294783_Chip-Seq_NPCs_Mouse1.21718937
64STAT6_21828071_ChIP-Seq_BEAS2B_Human1.21235474
65NANOG_16153702_ChIP-ChIP_HESCs_Human1.20989590
66POU5F1_16153702_ChIP-ChIP_HESCs_Human1.19759168
67* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.19460497
68TCF7_22412390_ChIP-Seq_EML_Mouse1.19401415
69FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.19088251
70PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19079365
71NELFA_20434984_ChIP-Seq_ESCs_Mouse1.18184069
72SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.18090341
73MYC_22102868_ChIP-Seq_BL_Human1.18079012
74DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.17084943
75STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.16072055
76NOTCH1_21737748_ChIP-Seq_TLL_Human1.15492556
77KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.15250530
78KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.15250530
79KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.15250530
80NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.15207539
81PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12510012
82NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.12337184
83MYCN_18555785_ChIP-Seq_MESCs_Mouse1.11148786
84GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.11054551
85CJUN_26792858_Chip-Seq_BT549_Human1.10922834
86TCF3_18692474_ChIP-Seq_MEFs_Mouse1.09860758
87SOX2_16153702_ChIP-ChIP_HESCs_Human1.09249134
88KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.07912955
89* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.06856720
90ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.05952918
91TCF3_18692474_ChIP-Seq_MESCs_Mouse1.05682696
92FOXM1_26456572_ChIP-Seq_MCF-7_Human1.05090762
93FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03675726
94P300_19829295_ChIP-Seq_ESCs_Human1.03578265
95* NANOG_21062744_ChIP-ChIP_HESCs_Human1.03240307
96MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02978858
97SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.02882412
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02231247
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.02231247
100KDM2B_26808549_Chip-Seq_JURKAT_Human1.01902168
101AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.01730586
102ESR2_21235772_ChIP-Seq_MCF-7_Human1.01703764
103KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.00462058
104SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.00126440
105NRF2_20460467_ChIP-Seq_MEFs_Mouse0.99794325
106NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.99794325
107TAF15_26573619_Chip-Seq_HEK293_Human0.99638776
108POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.98931304
109* EWS_26573619_Chip-Seq_HEK293_Human0.98511322
110RXR_22108803_ChIP-Seq_LS180_Human0.98459827
111PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.96839790
112ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.96743197
113SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.95857171
114CDX2_19796622_ChIP-Seq_MESCs_Mouse0.95413707
115CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.95393604
116UBF1/2_26484160_Chip-Seq_HMECs_Human0.94843359
117CHD1_26751641_Chip-Seq_LNCaP_Human0.93275295
118* E2F4_17652178_ChIP-ChIP_JURKAT_Human0.92907084
119SOX2_18555785_ChIP-Seq_MESCs_Mouse0.92725698
120NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.92634256
121* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.92483473
122ZFP281_18757296_ChIP-ChIP_E14_Mouse0.92204467
123PIAS1_25552417_ChIP-Seq_VCAP_Human0.92063872
124* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.91369771
125YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.91306148
126SOX9_24532713_ChIP-Seq_HFSC_Mouse0.90749167
127ZFX_18555785_ChIP-Seq_MESCs_Mouse0.90311708
128EP300_21415370_ChIP-Seq_HL-1_Mouse0.89916105
129POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.89799260
130ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.89207098
131* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.88448664
132IGF1R_20145208_ChIP-Seq_DFB_Human0.88351103
133Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.88285138
134EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.87369992
135DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.87351175
136* AHR_22903824_ChIP-Seq_MCF-7_Human0.87205617
137TBX3_20139965_ChIP-Seq_MESCs_Mouse0.87178250
138POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.86715940
139OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.86635982
140RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.85890077
141VDR_24787735_ChIP-Seq_THP-1_Human0.85760618
142TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.85411686
143* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.84269571
144TBX3_20139965_ChIP-Seq_ESCs_Mouse0.83219626

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009053_abnormal_anal_canal3.96552954
2MP0010030_abnormal_orbit_morphology3.12406347
3MP0000566_synostosis2.79265585
4MP0000537_abnormal_urethra_morphology2.76851882
5MP0005076_abnormal_cell_differentiation2.75922905
6MP0000569_abnormal_digit_pigmentation2.59119828
7MP0003705_abnormal_hypodermis_morpholog2.50797766
8MP0005187_abnormal_penis_morphology2.44844031
9MP0002282_abnormal_trachea_morphology2.39864284
10MP0004957_abnormal_blastocyst_morpholog2.35646614
11MP0002139_abnormal_hepatobiliary_system2.28725591
12MP0010094_abnormal_chromosome_stability2.27315185
13MP0003890_abnormal_embryonic-extraembry2.14439417
14MP0005248_abnormal_Harderian_gland2.13468922
15MP0000383_abnormal_hair_follicle2.05157045
16MP0003077_abnormal_cell_cycle2.01561805
17MP0003111_abnormal_nucleus_morphology1.99323597
18MP0005360_urolithiasis1.96895101
19MP0003693_abnormal_embryo_hatching1.95998530
20MP0010307_abnormal_tumor_latency1.92954009
21MP0003221_abnormal_cardiomyocyte_apopto1.92444126
22MP0009672_abnormal_birth_weight1.91692934
23MP0010352_gastrointestinal_tract_polyps1.84728838
24MP0010678_abnormal_skin_adnexa1.78908806
25MP0001730_embryonic_growth_arrest1.77891531
26MP0005085_abnormal_gallbladder_physiolo1.71833643
27MP0004264_abnormal_extraembryonic_tissu1.71333487
28MP0003941_abnormal_skin_development1.70481373
29MP0010234_abnormal_vibrissa_follicle1.70146721
30MP0003303_peritoneal_inflammation1.64326819
31MP0005367_renal/urinary_system_phenotyp1.62940477
32MP0000516_abnormal_urinary_system1.62940477
33MP0002009_preneoplasia1.61414191
34MP0002138_abnormal_hepatobiliary_system1.59698993
35MP0003121_genomic_imprinting1.59358611
36MP0005365_abnormal_bile_salt1.57660339
37MP0003315_abnormal_perineum_morphology1.56869002
38MP0000350_abnormal_cell_proliferation1.55134459
39MP0001697_abnormal_embryo_size1.54962170
40MP0003122_maternal_imprinting1.53960201
41MP0003385_abnormal_body_wall1.53761170
42MP0008932_abnormal_embryonic_tissue1.49165810
43MP0002938_white_spotting1.47407300
44MP0002932_abnormal_joint_morphology1.45569731
45MP0001340_abnormal_eyelid_morphology1.44964183
46MP0003252_abnormal_bile_duct1.43982068
47MP0002098_abnormal_vibrissa_morphology1.43960087
48MP0008058_abnormal_DNA_repair1.40941773
49MP0003937_abnormal_limbs/digits/tail_de1.40098753
50MP0006054_spinal_hemorrhage1.39380771
51MP0003942_abnormal_urinary_system1.39094747
52MP0000647_abnormal_sebaceous_gland1.38426678
53MP0001346_abnormal_lacrimal_gland1.38129869
54MP0002697_abnormal_eye_size1.37718058
55MP0004197_abnormal_fetal_growth/weight/1.37505991
56MP0002092_abnormal_eye_morphology1.35589050
57MP0009250_abnormal_appendicular_skeleto1.34946485
58MP0003755_abnormal_palate_morphology1.34892944
59MP0001286_abnormal_eye_development1.31971760
60MP0003935_abnormal_craniofacial_develop1.31330589
61MP0000778_abnormal_nervous_system1.29808351
62MP0000733_abnormal_muscle_development1.29271660
63MP0003119_abnormal_digestive_system1.28363154
64MP0001293_anophthalmia1.26805500
65MP0002254_reproductive_system_inflammat1.24143119
66MP0001915_intracranial_hemorrhage1.22136525
67MP0001299_abnormal_eye_distance/1.16854309
68MP0009697_abnormal_copulation1.16297351
69MP0003115_abnormal_respiratory_system1.15874895
70MP0004808_abnormal_hematopoietic_stem1.15646418
71MP0003453_abnormal_keratinocyte_physiol1.13349598
72MP0002084_abnormal_developmental_patter1.13255174
73MP0002080_prenatal_lethality1.13081540
74MP0008961_abnormal_basal_metabolism1.08208669
75MP0005508_abnormal_skeleton_morphology1.07902959
76MP0002233_abnormal_nose_morphology1.07709316
77MP0003943_abnormal_hepatobiliary_system1.07406939
78MP0003091_abnormal_cell_migration1.07375054
79MP0002088_abnormal_embryonic_growth/wei1.07123525
80MP0000432_abnormal_head_morphology1.07072676
81MP0003195_calcinosis1.04076451
82MP0003567_abnormal_fetal_cardiomyocyte1.03165863
83MP0003436_decreased_susceptibility_to1.02823783
84MP0010368_abnormal_lymphatic_system1.01831524
85MP0002116_abnormal_craniofacial_bone1.01559738
86MP0003300_gastrointestinal_ulcer1.00754246
87MP0003984_embryonic_growth_retardation0.99943338
88MP0002796_impaired_skin_barrier0.99242632
89MP0000377_abnormal_hair_follicle0.99242344
90MP0001216_abnormal_epidermal_layer0.98840497
91MP0002109_abnormal_limb_morphology0.98662430
92MP0005503_abnormal_tendon_morphology0.97633160
93MP0000428_abnormal_craniofacial_morphol0.97536112
94MP0002086_abnormal_extraembryonic_tissu0.97499438
95MP0004185_abnormal_adipocyte_glucose0.97292510
96MP0008057_abnormal_DNA_replication0.96840553
97MP0008004_abnormal_stomach_pH0.96275699
98MP0002234_abnormal_pharynx_morphology0.95953047
99MP0002111_abnormal_tail_morphology0.95531406
100MP0001672_abnormal_embryogenesis/_devel0.95463887
101MP0005380_embryogenesis_phenotype0.95463887
102MP0004947_skin_inflammation0.93167313
103MP0004272_abnormal_basement_membrane0.91741206
104MP0009703_decreased_birth_body0.91239719
105MP0000579_abnormal_nail_morphology0.90393302
106MP0005275_abnormal_skin_tensile0.90290713
107MP0002085_abnormal_embryonic_tissue0.90060432
108MP0002006_tumorigenesis0.89670418
109MP0008995_early_reproductive_senescence0.89249674
110MP0002925_abnormal_cardiovascular_devel0.88821267
111MP0000427_abnormal_hair_cycle0.88185591
112MP0002166_altered_tumor_susceptibility0.87953891
113MP0003123_paternal_imprinting0.86943438
114MP0005257_abnormal_intraocular_pressure0.86024257
115MP0000467_abnormal_esophagus_morphology0.85143557
116MP0000767_abnormal_smooth_muscle0.85063864
117MP0002115_abnormal_skeleton_extremities0.83861988
118MP0002113_abnormal_skeleton_development0.83642171
119MP0002249_abnormal_larynx_morphology0.83508841
120MP0000163_abnormal_cartilage_morphology0.83436278
121MP0003566_abnormal_cell_adhesion0.80165517
122MP0003861_abnormal_nervous_system0.80093909
123MP0002081_perinatal_lethality0.79535308
124MP0003950_abnormal_plasma_membrane0.79479194
125MP0000627_abnormal_mammary_gland0.78554400
126MP0008007_abnormal_cellular_replicative0.77732382
127MP0002060_abnormal_skin_morphology0.77328551
128MP0000313_abnormal_cell_death0.75902978
129MP0010630_abnormal_cardiac_muscle0.73512111
130MP0001177_atelectasis0.70153244
131MP0005621_abnormal_cell_physiology0.69636959
132MP0005391_vision/eye_phenotype0.69125850
133MP0003868_abnormal_feces_composition0.67433484
134MP0005647_abnormal_sex_gland0.67253629
135MP0003718_maternal_effect0.65087373
136MP0002877_abnormal_melanocyte_morpholog0.63908706

Predicted human phenotypes

RankGene SetZ-score
1Short 4th metacarpal (HP:0010044)4.05381214
2Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)4.05381214
3Papillary thyroid carcinoma (HP:0002895)3.95786860
4Vitreoretinal degeneration (HP:0000655)3.47352243
5Nephroblastoma (Wilms tumor) (HP:0002667)3.26871626
6Abnormality of the 4th metacarpal (HP:0010012)3.26459142
7Chromosomal breakage induced by crosslinking agents (HP:0003221)3.21276840
8Embryonal renal neoplasm (HP:0011794)3.18464546
9Chromsome breakage (HP:0040012)3.09654787
10Curly hair (HP:0002212)2.99790118
11Hypoplastic labia majora (HP:0000059)2.96783716
12Asymmetry of the thorax (HP:0001555)2.93309747
13Thyroid carcinoma (HP:0002890)2.84002718
14Midline defect of the nose (HP:0004122)2.63377133
15Abnormality of the labia majora (HP:0012881)2.61002921
16Cortical dysplasia (HP:0002539)2.56232769
17Abnormal lung lobation (HP:0002101)2.46653225
18Volvulus (HP:0002580)2.41462707
19Rhabdomyosarcoma (HP:0002859)2.39785209
20Hepatoblastoma (HP:0002884)2.39645001
21Abnormality of the nasal septum (HP:0000419)2.32440456
22Persistence of primary teeth (HP:0006335)2.31607556
23Deep venous thrombosis (HP:0002625)2.31445514
24Oligodontia (HP:0000677)2.29409531
25Abnormality of chromosome stability (HP:0003220)2.27347082
26Overlapping toe (HP:0001845)2.25916463
27Short middle phalanx of the 5th finger (HP:0004220)2.25012128
28Spastic diplegia (HP:0001264)2.23694558
29Abnormal foot bone ossification (HP:0010675)2.23369065
30Hypoplastic ischia (HP:0003175)2.20951933
31Bifid tongue (HP:0010297)2.20772008
32Cystic hygroma (HP:0000476)2.19673295
33Abnormal tarsal ossification (HP:0008369)2.17204896
34Aplasia/Hypoplasia of the sternum (HP:0006714)2.17015551
35Labial hypoplasia (HP:0000066)2.16017202
36Limited elbow extension (HP:0001377)2.15101020
37Absent eyelashes (HP:0000561)2.14811401
38Missing ribs (HP:0000921)2.12603473
39High anterior hairline (HP:0009890)2.12018609
40Right ventricular cardiomyopathy (HP:0011663)2.10413117
41Renal duplication (HP:0000075)2.09367701
42Myelomeningocele (HP:0002475)2.08687806
43Acanthocytosis (HP:0001927)2.06106030
44Hypochromic microcytic anemia (HP:0004840)2.05489013
45Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.05026471
46Broad thumb (HP:0011304)2.03934743
47Short 5th finger (HP:0009237)2.03044091
48Intrahepatic cholestasis (HP:0001406)2.01506628
49Termporal pattern (HP:0011008)2.01011051
50Insidious onset (HP:0003587)2.01011051
51Broad palm (HP:0001169)2.00802456
52Narrow palate (HP:0000189)2.00564743
53Malignant gastrointestinal tract tumors (HP:0006749)1.99543317
54Gastrointestinal carcinoma (HP:0002672)1.99543317
55Cutaneous finger syndactyly (HP:0010554)1.99333471
56Abnormality of the ischium (HP:0003174)1.98139022
57Abnormality of the intervertebral disk (HP:0005108)1.96421485
58Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.95905074
59Mitral valve prolapse (HP:0001634)1.95062031
60Supernumerary ribs (HP:0005815)1.94946866
61Uterine neoplasm (HP:0010784)1.94728361
62Spinal cord lesions (HP:0100561)1.93542467
63Syringomyelia (HP:0003396)1.93542467
64Biliary tract neoplasm (HP:0100574)1.93529842
65Epidermoid cyst (HP:0200040)1.93146952
66Colon cancer (HP:0003003)1.92491551
67Heterotopia (HP:0002282)1.92034477
68Hypobetalipoproteinemia (HP:0003563)1.91557422
69Increased number of teeth (HP:0011069)1.91138979
70Abnormality of the lumbar spine (HP:0100712)1.90513368
71Absent radius (HP:0003974)1.90305922
72Abnormality of the phalanges of the 2nd finger (HP:0009541)1.90257574
73Epiphyseal dysplasia (HP:0002656)1.89024599
74Capillary hemangiomas (HP:0005306)1.88501257
75Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.87635863
76Transitional cell carcinoma of the bladder (HP:0006740)1.87354855
77Obsessive-compulsive behavior (HP:0000722)1.85707722
78Coronal craniosynostosis (HP:0004440)1.84966916
79Abnormality of the phalanges of the 5th finger (HP:0004213)1.84033251
80Bifid scrotum (HP:0000048)1.83950686
81Meckel diverticulum (HP:0002245)1.83918459
82Absent frontal sinuses (HP:0002688)1.83719910
832-3 toe syndactyly (HP:0004691)1.83650347
84Wide nose (HP:0000445)1.83308019
85Abnormality of chromosome segregation (HP:0002916)1.82890131
86Lymphangioma (HP:0100764)1.81880742
87Abnormality of the 2nd finger (HP:0004100)1.79583324
88Skull defect (HP:0001362)1.79430519
89Anal stenosis (HP:0002025)1.78835228
90Embryonal neoplasm (HP:0002898)1.78362838
91Long eyelashes (HP:0000527)1.77549699
92Cubitus valgus (HP:0002967)1.77490947
93Relative macrocephaly (HP:0004482)1.77013034
94Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.76752378
95Oligodactyly (HP:0012165)1.76650836
96Short middle phalanx of finger (HP:0005819)1.76426216
97Chorioretinal atrophy (HP:0000533)1.75619517
98Bladder neoplasm (HP:0009725)1.75364984
99Bladder carcinoma (HP:0002862)1.75364984
100Acute lymphatic leukemia (HP:0006721)1.74933273
101Oligodactyly (hands) (HP:0001180)1.74369929
102Hypoplastic female external genitalia (HP:0012815)1.74276806
103Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.73980239
104Pulmonic stenosis (HP:0001642)1.73728498
105Myocardial infarction (HP:0001658)1.73452253
106Abnormal number of incisors (HP:0011064)1.72477749
107Wide anterior fontanel (HP:0000260)1.71635105
108Neoplasm of the small intestine (HP:0100833)1.71528331
109Leiomyosarcoma (HP:0100243)1.71276560
110Uterine leiomyosarcoma (HP:0002891)1.71276560
111Subacute progressive viral hepatitis (HP:0006572)1.71252409
112Omphalocele (HP:0001539)1.71189762
113Renal cell carcinoma (HP:0005584)1.70970476
114Large earlobe (HP:0009748)1.70250278
115Complement deficiency (HP:0004431)1.70148099
116Abnormality of the distal phalanx of the thumb (HP:0009617)1.69267526
117Abnormal ventriculo-arterial connection (HP:0011563)1.68976953
118Transposition of the great arteries (HP:0001669)1.68976953
119Abnormal connection of the cardiac segments (HP:0011545)1.68976953
120Exotropia (HP:0000577)1.68974556
121Abnormality of monocarboxylic acid metabolism (HP:0010996)1.68755070
122Abnormality of the common coagulation pathway (HP:0010990)1.68302394
123Diastasis recti (HP:0001540)1.68102881
124Aplasia involving forearm bones (HP:0009822)1.67965719
125Absent forearm bone (HP:0003953)1.67965719
126Preaxial foot polydactyly (HP:0001841)1.67809602
127Anophthalmia (HP:0000528)1.67037962
128Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.66913907
129Abnormality of the ileum (HP:0001549)1.66629825
130Acute myeloid leukemia (HP:0004808)1.66477787
131Shoulder girdle muscle weakness (HP:0003547)1.65968952
132Flat acetabular roof (HP:0003180)1.65883105
133Esophageal varix (HP:0002040)1.64918692
134Thickened helices (HP:0000391)1.64264399
135Osteomalacia (HP:0002749)1.64152486
136Choanal stenosis (HP:0000452)1.64111902
137Tetraparesis (HP:0002273)1.63657171
138Proximal tubulopathy (HP:0000114)1.63367721
139Cutaneous syndactyly (HP:0012725)1.63248762
140Progressive external ophthalmoplegia (HP:0000590)1.63155534
141Abnormality of the pubic bones (HP:0003172)1.63033425
142Trigonocephaly (HP:0000243)1.62974131
143Aortic aneurysm (HP:0004942)1.62848600
144Exostoses (HP:0100777)1.62816216
145Shallow orbits (HP:0000586)1.62581087
146Intestinal atresia (HP:0011100)1.62542370
147Lip pit (HP:0100267)1.62210864
148Supernumerary bones of the axial skeleton (HP:0009144)1.60384041
149Abnormality of the incisor (HP:0000676)1.59424096
150Cutis marmorata (HP:0000965)1.59361370
151Absent eyebrow (HP:0002223)1.57207645
152Hypoplasia of the maxilla (HP:0000327)1.56740015
153Medulloblastoma (HP:0002885)1.56567304
154Deep philtrum (HP:0002002)1.55506654
155Dental malocclusion (HP:0000689)1.54803381
156Natal tooth (HP:0000695)1.54475927
157Patellar dislocation (HP:0002999)1.54411400
158Broad phalanges of the hand (HP:0009768)1.54390558
159Hematochezia (HP:0002573)1.54199349
160Increased nuchal translucency (HP:0010880)1.54086153
161Deviation of the thumb (HP:0009603)1.53741376
162Abnormality of the parietal bone (HP:0002696)1.53570688
163Short clavicles (HP:0000894)1.53218491
164Bilateral microphthalmos (HP:0007633)1.52983335

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FGFR23.20457657
2LATS13.15662223
3EPHB23.11371495
4EPHA33.07856104
5SIK33.02816839
6CDK122.90411381
7MAP3K102.75762794
8LATS22.75689039
9KSR12.73581657
10STK38L2.65811822
11BRD42.58569877
12BCR2.40102735
13FGFR42.17344288
14FGFR32.16074467
15ERBB32.15671748
16BRSK22.07356439
17SIK12.06898292
18MAP3K142.02240114
19WEE12.01968358
20TTK1.91322630
21ERBB21.91293568
22RIPK11.84425047
23CHUK1.82482553
24TGFBR11.78028517
25ACVR1B1.65603245
26AKT31.64657374
27FGFR11.62623841
28DYRK1B1.59626259
29EPHA21.57367621
30PDGFRA1.56643517
31EIF2AK31.55766499
32MAP3K41.55111670
33DYRK31.41546457
34TAF11.39079971
35CDK61.37574416
36DYRK21.36352107
37MST1R1.31625938
38CASK1.30438512
39PLK41.30278453
40EEF2K1.27940623
41MAP3K31.27123813
42MELK1.27086217
43STK31.23313197
44PDGFRB1.18903119
45TNIK1.15365002
46NUAK11.14812612
47IRAK31.12516565
48CAMK1D1.10068664
49PTK61.10040738
50TAOK21.09563959
51TGFBR21.09311135
52ITK1.05993902
53MARK11.03864333
54MAP3K90.97853229
55PBK0.96429400
56CHEK20.95705326
57SRPK10.95423426
58BMPR1B0.94198046
59IKBKB0.92682047
60CAMK1G0.92052612
61MTOR0.90175918
62FER0.89782288
63ERBB40.87899226
64FRK0.86360162
65GSK3A0.84810465
66RPS6KA40.84162923
67DDR20.83438363
68MKNK10.83233635
69ICK0.81259306
70PIM10.81249039
71TRIM280.80791482
72BMPR20.76903241
73DYRK1A0.75736006
74RPS6KA10.75182434
75MET0.72832588
76YES10.70198285
77SGK20.69135816
78FLT30.68390330
79TBK10.66326860
80MAP3K20.65626227
81MST40.65575076
82PKN20.65478430
83CDK90.65474214
84MAP3K70.64424141
85CSNK1D0.64213125
86IRAK20.64161414
87CHEK10.60208227
88SIK20.59853586
89STK240.59037060
90PLK10.58821781
91BUB10.58380161
92IRAK10.58282713
93STK390.57630360
94MATK0.57585367
95ERN10.56165471
96TYRO30.56133126
97CSNK1A1L0.55637580
98INSRR0.53422364
99NEK10.52939519
100AKT20.52894887
101SCYL20.52283251
102CLK10.52057657
103CDK70.51822177
104DMPK0.51461064
105SGK30.49973742
106CDK30.49654136
107ALK0.48889891
108MAP3K60.48641796
109MAPK90.48022623
110ATR0.47388414
111RPS6KA50.46814923
112EIF2AK20.44701976
113CDK40.44223117
114AKT10.43403091
115MKNK20.43200616
116CDK20.42884712
117CSNK1E0.42840287
118RPS6KB20.42651998
119PLK30.41926799
120STK100.41390312
121PNCK0.40608855
122KSR20.40481878
123IKBKE0.40222092
124TXK0.39819027
125NEK20.39208293
126ATM0.39046540
127CDC70.38984718
128TSSK60.38877949
129MAP3K50.38763281
130CDK10.38630009
131PIK3CA0.37567627
132MAPK10.37417139
133EGFR0.36827257
134MAPK100.36618737
135TLK10.36201755
136SGK2230.35731784
137PASK0.35590072
138RET0.35118359
139CSNK1G10.34652953
140IGF1R0.34465715
141MAPK80.34198636
142NLK0.34070385
143AURKB0.33243325

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal cell carcinoma_Homo sapiens_hsa052172.53626309
2Primary bile acid biosynthesis_Homo sapiens_hsa001202.40289089
3Non-homologous end-joining_Homo sapiens_hsa034502.18558835
4Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045502.03841563
5Complement and coagulation cascades_Homo sapiens_hsa046101.89814392
6Thyroid cancer_Homo sapiens_hsa052161.85364343
7Steroid biosynthesis_Homo sapiens_hsa001001.81742420
8MicroRNAs in cancer_Homo sapiens_hsa052061.80798981
9Hippo signaling pathway_Homo sapiens_hsa043901.77191992
10Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.76212111
11RNA transport_Homo sapiens_hsa030131.74410105
12Lysine degradation_Homo sapiens_hsa003101.71261854
13Notch signaling pathway_Homo sapiens_hsa043301.67177286
14NF-kappa B signaling pathway_Homo sapiens_hsa040641.62951366
15Adherens junction_Homo sapiens_hsa045201.61847841
16Systemic lupus erythematosus_Homo sapiens_hsa053221.61003824
17TGF-beta signaling pathway_Homo sapiens_hsa043501.59769076
18Staphylococcus aureus infection_Homo sapiens_hsa051501.57602436
19Hedgehog signaling pathway_Homo sapiens_hsa043401.53547414
20Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.48773068
21Arginine biosynthesis_Homo sapiens_hsa002201.46960691
22Mismatch repair_Homo sapiens_hsa034301.44565441
23p53 signaling pathway_Homo sapiens_hsa041151.42003146
24Colorectal cancer_Homo sapiens_hsa052101.38304758
25T cell receptor signaling pathway_Homo sapiens_hsa046601.38242738
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.38223007
27Chronic myeloid leukemia_Homo sapiens_hsa052201.38160618
28Nitrogen metabolism_Homo sapiens_hsa009101.34245413
29Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.34186282
30Small cell lung cancer_Homo sapiens_hsa052221.30216526
31TNF signaling pathway_Homo sapiens_hsa046681.29776849
32Proteoglycans in cancer_Homo sapiens_hsa052051.29706173
33Viral myocarditis_Homo sapiens_hsa054161.28871021
34Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.26813540
35Selenocompound metabolism_Homo sapiens_hsa004501.25323732
36Transcriptional misregulation in cancer_Homo sapiens_hsa052021.23131478
37Allograft rejection_Homo sapiens_hsa053301.23036927
38HTLV-I infection_Homo sapiens_hsa051661.22586666
39DNA replication_Homo sapiens_hsa030301.18322947
40Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.17792805
41Axon guidance_Homo sapiens_hsa043601.16265991
42Hepatitis B_Homo sapiens_hsa051611.15858410
43Endometrial cancer_Homo sapiens_hsa052131.13567772
44RNA degradation_Homo sapiens_hsa030181.10324183
45NOD-like receptor signaling pathway_Homo sapiens_hsa046211.10009294
46Prostate cancer_Homo sapiens_hsa052151.09799948
47Leishmaniasis_Homo sapiens_hsa051401.05874588
48Toxoplasmosis_Homo sapiens_hsa051451.05247824
49Herpes simplex infection_Homo sapiens_hsa051681.04514724
50Insulin resistance_Homo sapiens_hsa049311.04439411
51Tryptophan metabolism_Homo sapiens_hsa003801.04286899
52Wnt signaling pathway_Homo sapiens_hsa043101.04269979
53Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.04010381
54Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.02098411
55Graft-versus-host disease_Homo sapiens_hsa053321.01274419
56Legionellosis_Homo sapiens_hsa051340.99519324
57Osteoclast differentiation_Homo sapiens_hsa043800.99413766
58Fatty acid biosynthesis_Homo sapiens_hsa000610.98720802
59AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.98705021
60Tight junction_Homo sapiens_hsa045300.96380487
61Viral carcinogenesis_Homo sapiens_hsa052030.96113330
62Retinol metabolism_Homo sapiens_hsa008300.95020031
63Steroid hormone biosynthesis_Homo sapiens_hsa001400.93876910
64Vitamin digestion and absorption_Homo sapiens_hsa049770.91078582
65FoxO signaling pathway_Homo sapiens_hsa040680.89734036
66ECM-receptor interaction_Homo sapiens_hsa045120.87019564
67Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.86966428
68Fanconi anemia pathway_Homo sapiens_hsa034600.85160310
69Pancreatic cancer_Homo sapiens_hsa052120.84447212
70Basal transcription factors_Homo sapiens_hsa030220.80989402
71Sphingolipid metabolism_Homo sapiens_hsa006000.80523438
72Prolactin signaling pathway_Homo sapiens_hsa049170.80299374
73Pathways in cancer_Homo sapiens_hsa052000.79732932
74Bladder cancer_Homo sapiens_hsa052190.79510718
75Autoimmune thyroid disease_Homo sapiens_hsa053200.78440230
76Measles_Homo sapiens_hsa051620.75902111
77Longevity regulating pathway - mammal_Homo sapiens_hsa042110.75764264
78Renal cell carcinoma_Homo sapiens_hsa052110.75265711
79Toll-like receptor signaling pathway_Homo sapiens_hsa046200.74844996
80mTOR signaling pathway_Homo sapiens_hsa041500.74050489
81Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73938830
82mRNA surveillance pathway_Homo sapiens_hsa030150.72884340
83Influenza A_Homo sapiens_hsa051640.72795931
84Focal adhesion_Homo sapiens_hsa045100.72284906
85Amoebiasis_Homo sapiens_hsa051460.72000593
86Fat digestion and absorption_Homo sapiens_hsa049750.70847504
87Dorso-ventral axis formation_Homo sapiens_hsa043200.68767488
88Apoptosis_Homo sapiens_hsa042100.68595321
89Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.67936725
90Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.67909052
91Type II diabetes mellitus_Homo sapiens_hsa049300.66910852
92Circadian rhythm_Homo sapiens_hsa047100.66188660
93African trypanosomiasis_Homo sapiens_hsa051430.65918451
94HIF-1 signaling pathway_Homo sapiens_hsa040660.65879846
95One carbon pool by folate_Homo sapiens_hsa006700.65844320
96Choline metabolism in cancer_Homo sapiens_hsa052310.65657570
97Cysteine and methionine metabolism_Homo sapiens_hsa002700.65575618
98Alcoholism_Homo sapiens_hsa050340.65094180
99Inositol phosphate metabolism_Homo sapiens_hsa005620.63878244
100Intestinal immune network for IgA production_Homo sapiens_hsa046720.62052186
101RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.61136924
102Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.60493417
103Insulin signaling pathway_Homo sapiens_hsa049100.59524372
104PI3K-Akt signaling pathway_Homo sapiens_hsa041510.59464261
105ErbB signaling pathway_Homo sapiens_hsa040120.58926204
106Salmonella infection_Homo sapiens_hsa051320.58837772
107Melanogenesis_Homo sapiens_hsa049160.58755661
108Adipocytokine signaling pathway_Homo sapiens_hsa049200.58477481
109Maturity onset diabetes of the young_Homo sapiens_hsa049500.58248955
110Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.58240845
111Pentose and glucuronate interconversions_Homo sapiens_hsa000400.58049380
112Melanoma_Homo sapiens_hsa052180.57822464
113Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.57554872
114Thyroid hormone signaling pathway_Homo sapiens_hsa049190.57446772
115Hepatitis C_Homo sapiens_hsa051600.57377065
116Glioma_Homo sapiens_hsa052140.57136817
117Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.56712380
118Asthma_Homo sapiens_hsa053100.56515765
119Cell cycle_Homo sapiens_hsa041100.56329638
120Jak-STAT signaling pathway_Homo sapiens_hsa046300.55710410
121Caffeine metabolism_Homo sapiens_hsa002320.54450910
122Acute myeloid leukemia_Homo sapiens_hsa052210.53744239
123Neurotrophin signaling pathway_Homo sapiens_hsa047220.53371679
124Spliceosome_Homo sapiens_hsa030400.53363381
125Prion diseases_Homo sapiens_hsa050200.52927364
126Central carbon metabolism in cancer_Homo sapiens_hsa052300.52604790
127Malaria_Homo sapiens_hsa051440.51890326
128Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.51273732
129Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.50917982
130Nucleotide excision repair_Homo sapiens_hsa034200.50117984
131Shigellosis_Homo sapiens_hsa051310.49660995
132Non-small cell lung cancer_Homo sapiens_hsa052230.49021625
133Pertussis_Homo sapiens_hsa051330.48849009
134Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.48607008

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »