Rank | Gene Set | Z-score |
---|---|---|
1 | mitotic metaphase plate congression (GO:0007080) | 5.50969873 |
2 | metaphase plate congression (GO:0051310) | 5.45805506 |
3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.40905143 |
4 | regulation of mitotic spindle organization (GO:0060236) | 5.14606830 |
5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.97343203 |
6 | ATP synthesis coupled proton transport (GO:0015986) | 4.97343203 |
7 | regulation of spindle organization (GO:0090224) | 4.90963991 |
8 | fatty acid elongation (GO:0030497) | 4.71245610 |
9 | protein localization to kinetochore (GO:0034501) | 4.66698890 |
10 | neuron cell-cell adhesion (GO:0007158) | 4.62504176 |
11 | central nervous system myelination (GO:0022010) | 4.59824585 |
12 | axon ensheathment in central nervous system (GO:0032291) | 4.59824585 |
13 | chaperone-mediated protein transport (GO:0072321) | 4.31609715 |
14 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.28731957 |
15 | protein localization to chromosome, centromeric region (GO:0071459) | 4.22266693 |
16 | DNA topological change (GO:0006265) | 4.19545185 |
17 | synaptic vesicle exocytosis (GO:0016079) | 4.16632512 |
18 | spindle checkpoint (GO:0031577) | 4.12804119 |
19 | chromatin remodeling at centromere (GO:0031055) | 4.05442115 |
20 | dopamine transport (GO:0015872) | 3.99806290 |
21 | protein neddylation (GO:0045116) | 3.96887360 |
22 | mitotic sister chromatid segregation (GO:0000070) | 3.96389004 |
23 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.95630383 |
24 | negative regulation of neurotransmitter transport (GO:0051589) | 3.85475176 |
25 | respiratory electron transport chain (GO:0022904) | 3.77177012 |
26 | mitotic spindle checkpoint (GO:0071174) | 3.76660808 |
27 | regulation of chromosome segregation (GO:0051983) | 3.74027650 |
28 | electron transport chain (GO:0022900) | 3.69055408 |
29 | mitotic chromosome condensation (GO:0007076) | 3.67637318 |
30 | ATP hydrolysis coupled proton transport (GO:0015991) | 3.64454176 |
31 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 3.64454176 |
32 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.63125794 |
33 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.61558426 |
34 | DNA double-strand break processing (GO:0000729) | 3.61553413 |
35 | resolution of meiotic recombination intermediates (GO:0000712) | 3.59884993 |
36 | mitotic spindle assembly checkpoint (GO:0007094) | 3.56550809 |
37 | neurotransmitter uptake (GO:0001504) | 3.55985439 |
38 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.55338083 |
39 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.55338083 |
40 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.55338083 |
41 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.55338083 |
42 | negative regulation of sister chromatid segregation (GO:0033046) | 3.55338083 |
43 | spindle assembly checkpoint (GO:0071173) | 3.53459782 |
44 | negative regulation of chromosome segregation (GO:0051985) | 3.52730626 |
45 | histone exchange (GO:0043486) | 3.48816272 |
46 | dopamine biosynthetic process (GO:0042416) | 3.45377491 |
47 | protein localization to chromosome (GO:0034502) | 3.40566106 |
48 | sister chromatid segregation (GO:0000819) | 3.39979172 |
49 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.39961016 |
50 | establishment of integrated proviral latency (GO:0075713) | 3.38046829 |
51 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.32239224 |
52 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.32239224 |
53 | negative regulation of microtubule polymerization (GO:0031115) | 3.31558932 |
54 | NADH dehydrogenase complex assembly (GO:0010257) | 3.30989588 |
55 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.30989588 |
56 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.30989588 |
57 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.29798601 |
58 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.29798601 |
59 | regulation of sister chromatid segregation (GO:0033045) | 3.29798601 |
60 | regulation of dopamine metabolic process (GO:0042053) | 3.28597693 |
61 | regulation of catecholamine metabolic process (GO:0042069) | 3.28597693 |
62 | meiotic chromosome segregation (GO:0045132) | 3.27584252 |
63 | chromosome segregation (GO:0007059) | 3.25790884 |
64 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.22764338 |
65 | mitotic spindle organization (GO:0007052) | 3.21580128 |
66 | substantia nigra development (GO:0021762) | 3.20193127 |
67 | protein localization to synapse (GO:0035418) | 3.19796889 |
68 | mating behavior (GO:0007617) | 3.19307636 |
69 | transferrin transport (GO:0033572) | 3.15164507 |
70 | DNA replication-independent nucleosome organization (GO:0034724) | 3.13986699 |
71 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.13986699 |
72 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.13209295 |
73 | microtubule polymerization or depolymerization (GO:0031109) | 3.12499981 |
74 | presynaptic membrane organization (GO:0097090) | 3.11942499 |
75 | presynaptic membrane assembly (GO:0097105) | 3.09437911 |
76 | kinetochore organization (GO:0051383) | 3.08054192 |
77 | glutamate receptor signaling pathway (GO:0007215) | 3.07471981 |
78 | response to histamine (GO:0034776) | 3.07196896 |
79 | glutamate secretion (GO:0014047) | 3.04697174 |
80 | synaptic transmission, dopaminergic (GO:0001963) | 3.03541893 |
81 | ventricular cardiac muscle cell development (GO:0055015) | 3.03416219 |
82 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.99938493 |
83 | negative regulation of mitosis (GO:0045839) | 2.94354731 |
84 | protein K6-linked ubiquitination (GO:0085020) | 2.93897995 |
85 | protein complex biogenesis (GO:0070271) | 2.93794653 |
86 | microtubule depolymerization (GO:0007019) | 2.93621103 |
87 | neuron recognition (GO:0008038) | 2.92292094 |
88 | vocalization behavior (GO:0071625) | 2.92134263 |
89 | catecholamine transport (GO:0051937) | 2.90910672 |
90 | establishment of viral latency (GO:0019043) | 2.90721634 |
91 | protein localization to cilium (GO:0061512) | 2.87081926 |
92 | neuron-neuron synaptic transmission (GO:0007270) | 2.85724775 |
93 | DNA ligation (GO:0006266) | 2.84963639 |
94 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.84662827 |
95 | positive regulation of chromosome segregation (GO:0051984) | 2.84140609 |
96 | trivalent inorganic cation transport (GO:0072512) | 2.83927132 |
97 | ferric iron transport (GO:0015682) | 2.83927132 |
98 | transmission of nerve impulse (GO:0019226) | 2.83782687 |
99 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.83272280 |
100 | limb bud formation (GO:0060174) | 2.83071334 |
101 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.78631686 |
102 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.78588904 |
103 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.78357202 |
104 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 2.78072564 |
105 | mitotic cytokinesis (GO:0000281) | 2.76809222 |
106 | neuronal action potential propagation (GO:0019227) | 2.76060356 |
107 | hydrogen ion transmembrane transport (GO:1902600) | 2.75103952 |
108 | positive regulation of synapse assembly (GO:0051965) | 2.72916607 |
109 | response to insecticide (GO:0017085) | 2.72135162 |
110 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.70822289 |
111 | kinetochore assembly (GO:0051382) | 2.70442753 |
112 | neurotransmitter transport (GO:0006836) | 2.69198803 |
113 | inner mitochondrial membrane organization (GO:0007007) | 2.69093428 |
114 | negative regulation of DNA recombination (GO:0045910) | 2.65864074 |
115 | centriole replication (GO:0007099) | 2.65413270 |
116 | chromosome condensation (GO:0030261) | 2.64427172 |
117 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.64204938 |
118 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.63413841 |
119 | regulation of centriole replication (GO:0046599) | 2.63006284 |
120 | regulation of glutamate secretion (GO:0014048) | 2.62526152 |
121 | histone H2A acetylation (GO:0043968) | 2.62509143 |
122 | negative regulation of nuclear division (GO:0051784) | 2.60340259 |
123 | postsynaptic membrane organization (GO:0001941) | 2.59199860 |
124 | establishment of chromosome localization (GO:0051303) | 2.58315786 |
125 | negative regulation of cell division (GO:0051782) | 2.57264074 |
126 | proton transport (GO:0015992) | 2.56935035 |
127 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.56863745 |
128 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.56863745 |
129 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.56863745 |
130 | neurotransmitter secretion (GO:0007269) | 2.56705401 |
131 | negative regulation of microtubule depolymerization (GO:0007026) | 2.56469804 |
132 | behavioral response to cocaine (GO:0048148) | 2.56127268 |
133 | phagosome maturation (GO:0090382) | 2.55559042 |
134 | axonal fasciculation (GO:0007413) | 2.55445577 |
135 | long-term synaptic potentiation (GO:0060291) | 2.55410049 |
136 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.54928168 |
137 | cholesterol biosynthetic process (GO:0006695) | 2.53824373 |
138 | hydrogen transport (GO:0006818) | 2.53052567 |
139 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.52649287 |
140 | establishment of synaptic vesicle localization (GO:0097480) | 2.52396616 |
141 | synaptic vesicle transport (GO:0048489) | 2.52396616 |
142 | regulation of centrosome cycle (GO:0046605) | 2.50748382 |
143 | mitotic nuclear envelope disassembly (GO:0007077) | 2.50502793 |
144 | cullin deneddylation (GO:0010388) | 2.50469974 |
145 | ATP biosynthetic process (GO:0006754) | 2.49861889 |
146 | mitotic nuclear division (GO:0007067) | 2.49519059 |
147 | regulation of neurotransmitter levels (GO:0001505) | 2.48685668 |
148 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.47150203 |
149 | establishment of mitochondrion localization (GO:0051654) | 2.45786294 |
150 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.45598806 |
151 | synaptic transmission, glutamatergic (GO:0035249) | 2.45426232 |
152 | spermatid nucleus differentiation (GO:0007289) | 2.45243989 |
153 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.45029805 |
154 | regulation of sister chromatid cohesion (GO:0007063) | 2.44751290 |
155 | spindle assembly involved in mitosis (GO:0090307) | 2.44558258 |
156 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.44530691 |
157 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.44153710 |
158 | nucleobase catabolic process (GO:0046113) | 2.43406817 |
159 | regulation of collateral sprouting (GO:0048670) | 2.43291209 |
160 | regulation of DNA endoreduplication (GO:0032875) | 2.43135595 |
161 | CENP-A containing nucleosome assembly (GO:0034080) | 2.42405136 |
162 | ATP-dependent chromatin remodeling (GO:0043044) | 2.42276507 |
163 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.42239536 |
164 | neurotransmitter catabolic process (GO:0042135) | 2.41342783 |
165 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435) | 2.40983971 |
166 | regulation of neurotransmitter uptake (GO:0051580) | 2.40924055 |
167 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.40737679 |
168 | protein K11-linked ubiquitination (GO:0070979) | 2.37493137 |
169 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.36841990 |
170 | regulation of microtubule depolymerization (GO:0031114) | 2.36704939 |
171 | negative regulation of proteasomal protein catabolic process (GO:1901799) | 2.34961125 |
172 | regulation of microtubule cytoskeleton organization (GO:0070507) | 2.34046189 |
173 | synaptic vesicle maturation (GO:0016188) | 2.33489639 |
174 | nuclear envelope disassembly (GO:0051081) | 2.31863716 |
175 | membrane disassembly (GO:0030397) | 2.31863716 |
176 | establishment of mitotic spindle localization (GO:0040001) | 2.31782434 |
177 | olfactory bulb development (GO:0021772) | 2.31130409 |
178 | mitotic cell cycle (GO:0000278) | 2.30190132 |
179 | G2/M transition of mitotic cell cycle (GO:0000086) | 2.29718307 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TAF15_26573619_Chip-Seq_HEK293_Human | 3.88233029 |
2 | * FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.84616357 |
3 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.69595352 |
4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.67982061 |
5 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.27734826 |
6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.15730639 |
7 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.01075260 |
8 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.71109987 |
9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.49514465 |
10 | FUS_26573619_Chip-Seq_HEK293_Human | 2.39524366 |
11 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.33016582 |
12 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.31864175 |
13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.30657116 |
14 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.28229863 |
15 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.28081498 |
16 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.26173323 |
17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.23037293 |
18 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.22587156 |
19 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.12849388 |
20 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.12202682 |
21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.09558936 |
22 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.08729850 |
23 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.03450203 |
24 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.03208567 |
25 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.94581139 |
26 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.94044175 |
27 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.93368910 |
28 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.91616211 |
29 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.90404696 |
30 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.89938556 |
31 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.87208237 |
32 | * EWS_26573619_Chip-Seq_HEK293_Human | 1.83985741 |
33 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.80516409 |
34 | P300_19829295_ChIP-Seq_ESCs_Human | 1.78160833 |
35 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.74913506 |
36 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.72744487 |
37 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.71738540 |
38 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.70458941 |
39 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.64454209 |
40 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.62948889 |
41 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.62614469 |
42 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.60837976 |
43 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.58360961 |
44 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.57721972 |
45 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.57274122 |
46 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.50554766 |
47 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.50056569 |
48 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.45172770 |
49 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.41299485 |
50 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.41208070 |
51 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.40817410 |
52 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.38691608 |
53 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.38121658 |
54 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.37171057 |
55 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.37019808 |
56 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.35043823 |
57 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.34753410 |
58 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.34514534 |
59 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.34464072 |
60 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.34166289 |
61 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.34100457 |
62 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.30256366 |
63 | * CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.29281142 |
64 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.28968529 |
65 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.27085687 |
66 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.25551420 |
67 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.25137801 |
68 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.24011290 |
69 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.21855358 |
70 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.19717129 |
71 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.19110412 |
72 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.19076951 |
73 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.18495906 |
74 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.18368529 |
75 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.18067778 |
76 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.17709989 |
77 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.16725889 |
78 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.16575016 |
79 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.15698310 |
80 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.15676112 |
81 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.14751387 |
82 | JUN_21703547_ChIP-Seq_K562_Human | 1.14443699 |
83 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.14353988 |
84 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.12928852 |
85 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.10812142 |
86 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.10812142 |
87 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.10021245 |
88 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.09378374 |
89 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.08727198 |
90 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.08552537 |
91 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.08445832 |
92 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.06052759 |
93 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.05632730 |
94 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.05523501 |
95 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.05329967 |
96 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.05098394 |
97 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.04224843 |
98 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.03572499 |
99 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.03189453 |
100 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.02591287 |
101 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.01998049 |
102 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.01710584 |
103 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.01655171 |
104 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.00966324 |
105 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.98622057 |
106 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.98356087 |
107 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.98234176 |
108 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.98118259 |
109 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 0.97469331 |
110 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.96990551 |
111 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.96548232 |
112 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.96489769 |
113 | * MYC_18940864_ChIP-ChIP_HL60_Human | 0.95839930 |
114 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.95034337 |
115 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94338408 |
116 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.94280677 |
117 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 0.94050238 |
118 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 0.93552431 |
119 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.92222798 |
120 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.91179960 |
121 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.90707300 |
122 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.89868882 |
123 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.89686626 |
124 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.88704156 |
125 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.88137865 |
126 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.88131831 |
127 | * FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.87908554 |
128 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.87296475 |
129 | * TTF2_22483619_ChIP-Seq_HELA_Human | 0.87264881 |
130 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86871101 |
131 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.86871101 |
132 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.86709704 |
133 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.86481169 |
134 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.85551535 |
135 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.84612971 |
136 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.84273137 |
137 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.82579589 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 5.47999094 |
2 | MP0001529_abnormal_vocalization | 3.98750689 |
3 | MP0004859_abnormal_synaptic_plasticity | 3.39036738 |
4 | MP0001968_abnormal_touch/_nociception | 3.05430221 |
5 | MP0002736_abnormal_nociception_after | 3.03245195 |
6 | MP0003635_abnormal_synaptic_transmissio | 2.99486042 |
7 | MP0001905_abnormal_dopamine_level | 2.99162585 |
8 | MP0002064_seizures | 2.94320740 |
9 | MP0009745_abnormal_behavioral_response | 2.83569899 |
10 | MP0006292_abnormal_olfactory_placode | 2.71929513 |
11 | MP0003693_abnormal_embryo_hatching | 2.59312551 |
12 | MP0003890_abnormal_embryonic-extraembry | 2.58188258 |
13 | MP0009046_muscle_twitch | 2.54837905 |
14 | MP0005423_abnormal_somatic_nervous | 2.52277515 |
15 | MP0002063_abnormal_learning/memory/cond | 2.49364017 |
16 | MP0002272_abnormal_nervous_system | 2.47716576 |
17 | MP0002572_abnormal_emotion/affect_behav | 2.42481261 |
18 | MP0004270_analgesia | 2.41600440 |
19 | MP0002735_abnormal_chemical_nociception | 2.35766550 |
20 | MP0006276_abnormal_autonomic_nervous | 2.33662134 |
21 | MP0001486_abnormal_startle_reflex | 2.21126117 |
22 | MP0001440_abnormal_grooming_behavior | 2.13513470 |
23 | MP0002734_abnormal_mechanical_nocicepti | 2.13377290 |
24 | MP0003329_amyloid_beta_deposits | 2.12538378 |
25 | MP0004142_abnormal_muscle_tone | 2.06833228 |
26 | MP0000566_synostosis | 2.05556639 |
27 | MP0003111_abnormal_nucleus_morphology | 2.03475126 |
28 | MP0002067_abnormal_sensory_capabilities | 1.99720882 |
29 | MP0002733_abnormal_thermal_nociception | 1.93460984 |
30 | MP0000920_abnormal_myelination | 1.92796266 |
31 | MP0003077_abnormal_cell_cycle | 1.90552564 |
32 | MP0001970_abnormal_pain_threshold | 1.84663367 |
33 | MP0000778_abnormal_nervous_system | 1.82332025 |
34 | MP0005551_abnormal_eye_electrophysiolog | 1.77604699 |
35 | MP0001501_abnormal_sleep_pattern | 1.76591342 |
36 | MP0005386_behavior/neurological_phenoty | 1.73988704 |
37 | MP0004924_abnormal_behavior | 1.73988704 |
38 | MP0001293_anophthalmia | 1.69972721 |
39 | MP0008789_abnormal_olfactory_epithelium | 1.69422942 |
40 | MP0010030_abnormal_orbit_morphology | 1.63796383 |
41 | MP0008058_abnormal_DNA_repair | 1.62762825 |
42 | MP0001984_abnormal_olfaction | 1.61503175 |
43 | MP0003122_maternal_imprinting | 1.59999901 |
44 | MP0008877_abnormal_DNA_methylation | 1.54411664 |
45 | MP0002938_white_spotting | 1.54272303 |
46 | MP0003937_abnormal_limbs/digits/tail_de | 1.51142194 |
47 | MP0002233_abnormal_nose_morphology | 1.45605217 |
48 | MP0005248_abnormal_Harderian_gland | 1.44177240 |
49 | MP0002557_abnormal_social/conspecific_i | 1.43225200 |
50 | MP0004742_abnormal_vestibular_system | 1.42625720 |
51 | MP0002184_abnormal_innervation | 1.40571908 |
52 | MP0002229_neurodegeneration | 1.38415069 |
53 | MP0003690_abnormal_glial_cell | 1.37272099 |
54 | MP0009379_abnormal_foot_pigmentation | 1.36446913 |
55 | MP0001188_hyperpigmentation | 1.36268698 |
56 | MP0009697_abnormal_copulation | 1.32701206 |
57 | MP0000537_abnormal_urethra_morphology | 1.32433720 |
58 | MP0002882_abnormal_neuron_morphology | 1.31639442 |
59 | MP0003632_abnormal_nervous_system | 1.31540872 |
60 | MP0002066_abnormal_motor_capabilities/c | 1.30475844 |
61 | MP0005646_abnormal_pituitary_gland | 1.29098569 |
62 | MP0004885_abnormal_endolymph | 1.28105070 |
63 | MP0004133_heterotaxia | 1.26036946 |
64 | MP0003634_abnormal_glial_cell | 1.25418534 |
65 | MP0003861_abnormal_nervous_system | 1.25269732 |
66 | MP0005409_darkened_coat_color | 1.24773729 |
67 | MP0003631_nervous_system_phenotype | 1.23793002 |
68 | MP0003119_abnormal_digestive_system | 1.22943627 |
69 | MP0001177_atelectasis | 1.22390866 |
70 | MP0006072_abnormal_retinal_apoptosis | 1.21793248 |
71 | MP0000955_abnormal_spinal_cord | 1.20662535 |
72 | MP0001963_abnormal_hearing_physiology | 1.20557465 |
73 | MP0002822_catalepsy | 1.19303070 |
74 | MP0001986_abnormal_taste_sensitivity | 1.18766333 |
75 | MP0001286_abnormal_eye_development | 1.18407656 |
76 | MP0002653_abnormal_ependyma_morphology | 1.17475761 |
77 | MP0008872_abnormal_physiological_respon | 1.17234422 |
78 | MP0000604_amyloidosis | 1.15915505 |
79 | MP0000647_abnormal_sebaceous_gland | 1.13239656 |
80 | MP0008569_lethality_at_weaning | 1.11393060 |
81 | MP0004811_abnormal_neuron_physiology | 1.11078370 |
82 | MP0000631_abnormal_neuroendocrine_gland | 1.10746652 |
83 | MP0003633_abnormal_nervous_system | 1.08336335 |
84 | MP0003755_abnormal_palate_morphology | 1.08000080 |
85 | MP0000049_abnormal_middle_ear | 1.06962224 |
86 | MP0005253_abnormal_eye_physiology | 1.06924182 |
87 | MP0003136_yellow_coat_color | 1.06682169 |
88 | MP0002697_abnormal_eye_size | 1.05650602 |
89 | MP0001485_abnormal_pinna_reflex | 1.04633594 |
90 | MP0001502_abnormal_circadian_rhythm | 1.04465966 |
91 | MP0002152_abnormal_brain_morphology | 1.04367860 |
92 | MP0002752_abnormal_somatic_nervous | 1.02519858 |
93 | MP0002234_abnormal_pharynx_morphology | 1.01736593 |
94 | MP0005645_abnormal_hypothalamus_physiol | 0.97824081 |
95 | MP0001346_abnormal_lacrimal_gland | 0.95222717 |
96 | MP0003385_abnormal_body_wall | 0.94793868 |
97 | MP0005410_abnormal_fertilization | 0.94421540 |
98 | MP0003567_abnormal_fetal_cardiomyocyte | 0.93994199 |
99 | MP0004957_abnormal_blastocyst_morpholog | 0.93818288 |
100 | MP0003121_genomic_imprinting | 0.93480661 |
101 | MP0005391_vision/eye_phenotype | 0.93452651 |
102 | MP0003315_abnormal_perineum_morphology | 0.93244784 |
103 | MP0003879_abnormal_hair_cell | 0.91642650 |
104 | MP0001929_abnormal_gametogenesis | 0.87653766 |
105 | MP0002210_abnormal_sex_determination | 0.87476812 |
106 | MP0008057_abnormal_DNA_replication | 0.87466753 |
107 | MP0003787_abnormal_imprinting | 0.87035660 |
108 | MP0005187_abnormal_penis_morphology | 0.86746001 |
109 | MP0002084_abnormal_developmental_patter | 0.86127549 |
110 | MP0004858_abnormal_nervous_system | 0.85465249 |
111 | MP0002638_abnormal_pupillary_reflex | 0.84847488 |
112 | MP0000026_abnormal_inner_ear | 0.84621054 |
113 | MP0001664_abnormal_digestion | 0.83556238 |
114 | MP0002090_abnormal_vision | 0.82775436 |
115 | MP0002085_abnormal_embryonic_tissue | 0.82157310 |
116 | MP0008932_abnormal_embryonic_tissue | 0.81420595 |
117 | MP0000427_abnormal_hair_cycle | 0.79836570 |
118 | MP0003011_delayed_dark_adaptation | 0.79541028 |
119 | MP0002876_abnormal_thyroid_physiology | 0.79081250 |
120 | MP0005195_abnormal_posterior_eye | 0.78926745 |
121 | MP0002102_abnormal_ear_morphology | 0.78415916 |
122 | MP0000372_irregular_coat_pigmentation | 0.76393785 |
123 | MP0006035_abnormal_mitochondrial_morpho | 0.74934705 |
124 | MP0010094_abnormal_chromosome_stability | 0.74804446 |
125 | MP0003123_paternal_imprinting | 0.73815487 |
126 | MP0005499_abnormal_olfactory_system | 0.73396669 |
127 | MP0005394_taste/olfaction_phenotype | 0.73396669 |
128 | MP0005171_absent_coat_pigmentation | 0.73016236 |
129 | MP0004147_increased_porphyrin_level | 0.72018763 |
130 | MP0006036_abnormal_mitochondrial_physio | 0.71795436 |
131 | MP0003950_abnormal_plasma_membrane | 0.71172060 |
132 | MP0002751_abnormal_autonomic_nervous | 0.70189744 |
133 | MP0003938_abnormal_ear_development | 0.69737277 |
134 | MP0003698_abnormal_male_reproductive | 0.69689971 |
135 | MP0002069_abnormal_eating/drinking_beha | 0.69152425 |
136 | MP0003718_maternal_effect | 0.68550186 |
137 | MP0005535_abnormal_body_temperature | 0.67574438 |
138 | MP0004043_abnormal_pH_regulation | 0.66021137 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 4.25865001 |
2 | Increased serum pyruvate (HP:0003542) | 4.15198091 |
3 | Abnormality of glycolysis (HP:0004366) | 4.15198091 |
4 | Cortical dysplasia (HP:0002539) | 3.93175768 |
5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.87495069 |
6 | Myokymia (HP:0002411) | 3.80847838 |
7 | Mitochondrial inheritance (HP:0001427) | 3.80394607 |
8 | Focal motor seizures (HP:0011153) | 3.69682412 |
9 | Progressive macrocephaly (HP:0004481) | 3.64634574 |
10 | Acute encephalopathy (HP:0006846) | 3.47332750 |
11 | Neurofibrillary tangles (HP:0002185) | 3.39341473 |
12 | Volvulus (HP:0002580) | 3.38146067 |
13 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 3.37124329 |
14 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 3.37124329 |
15 | Hepatocellular necrosis (HP:0001404) | 3.29183159 |
16 | Increased CSF lactate (HP:0002490) | 3.21784255 |
17 | Cerebral inclusion bodies (HP:0100314) | 3.10204887 |
18 | Atonic seizures (HP:0010819) | 3.07908097 |
19 | Leukodystrophy (HP:0002415) | 3.07182908 |
20 | Septo-optic dysplasia (HP:0100842) | 2.98721035 |
21 | Limb dystonia (HP:0002451) | 2.92417797 |
22 | Epileptic encephalopathy (HP:0200134) | 2.91335191 |
23 | Increased hepatocellular lipid droplets (HP:0006565) | 2.86062522 |
24 | Increased nuchal translucency (HP:0010880) | 2.84859156 |
25 | Pheochromocytoma (HP:0002666) | 2.83372507 |
26 | Neuroendocrine neoplasm (HP:0100634) | 2.79815760 |
27 | Abnormality of the corticospinal tract (HP:0002492) | 2.79303664 |
28 | Renal Fanconi syndrome (HP:0001994) | 2.76650624 |
29 | Visual hallucinations (HP:0002367) | 2.74480351 |
30 | Abnormal hair whorl (HP:0010721) | 2.70531694 |
31 | Gait imbalance (HP:0002141) | 2.62310105 |
32 | Parakeratosis (HP:0001036) | 2.61766200 |
33 | Oligodactyly (hands) (HP:0001180) | 2.58134213 |
34 | Absence seizures (HP:0002121) | 2.56512399 |
35 | Medial flaring of the eyebrow (HP:0010747) | 2.48749772 |
36 | Focal seizures (HP:0007359) | 2.48480461 |
37 | Dialeptic seizures (HP:0011146) | 2.46414420 |
38 | Progressive cerebellar ataxia (HP:0002073) | 2.43748988 |
39 | Congenital primary aphakia (HP:0007707) | 2.42164570 |
40 | Polyphagia (HP:0002591) | 2.39565443 |
41 | Optic disc pallor (HP:0000543) | 2.38098601 |
42 | Supranuclear gaze palsy (HP:0000605) | 2.37849985 |
43 | Nephrogenic diabetes insipidus (HP:0009806) | 2.37459868 |
44 | Colon cancer (HP:0003003) | 2.37310931 |
45 | Absent septum pellucidum (HP:0001331) | 2.36078325 |
46 | Vaginal atresia (HP:0000148) | 2.35910569 |
47 | Delusions (HP:0000746) | 2.35687038 |
48 | Genital tract atresia (HP:0001827) | 2.32348038 |
49 | Insidious onset (HP:0003587) | 2.32243089 |
50 | Termporal pattern (HP:0011008) | 2.32243089 |
51 | Cerebral hypomyelination (HP:0006808) | 2.31962631 |
52 | Lipid accumulation in hepatocytes (HP:0006561) | 2.31421051 |
53 | Generalized tonic-clonic seizures (HP:0002069) | 2.30112189 |
54 | Hepatic necrosis (HP:0002605) | 2.29882699 |
55 | Spastic gait (HP:0002064) | 2.27083337 |
56 | Meckel diverticulum (HP:0002245) | 2.25880736 |
57 | Hypoplastic pelvis (HP:0008839) | 2.25236571 |
58 | Hyperventilation (HP:0002883) | 2.22783209 |
59 | Abnormality of binocular vision (HP:0011514) | 2.22755734 |
60 | Diplopia (HP:0000651) | 2.22755734 |
61 | Abnormality of renal resorption (HP:0011038) | 2.21547641 |
62 | Stenosis of the external auditory canal (HP:0000402) | 2.19810371 |
63 | True hermaphroditism (HP:0010459) | 2.18010503 |
64 | Retinal dysplasia (HP:0007973) | 2.16207376 |
65 | Emotional lability (HP:0000712) | 2.15544462 |
66 | CNS hypomyelination (HP:0003429) | 2.14757794 |
67 | Truncal ataxia (HP:0002078) | 2.12420418 |
68 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.11599501 |
69 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.11320518 |
70 | Oligodactyly (HP:0012165) | 2.10390141 |
71 | Respiratory failure (HP:0002878) | 2.10278141 |
72 | Abnormality of the ileum (HP:0001549) | 2.10189220 |
73 | Hepatoblastoma (HP:0002884) | 2.09713174 |
74 | Abnormal eating behavior (HP:0100738) | 2.08123184 |
75 | Intestinal atresia (HP:0011100) | 2.07826754 |
76 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.07641824 |
77 | Abnormality of the septum pellucidum (HP:0007375) | 2.07279075 |
78 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.07053996 |
79 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.06906736 |
80 | Increased circulating renin level (HP:0000848) | 2.06046305 |
81 | Duodenal stenosis (HP:0100867) | 2.05915594 |
82 | Small intestinal stenosis (HP:0012848) | 2.05915594 |
83 | Abnormal ciliary motility (HP:0012262) | 2.05394170 |
84 | Abnormality of the duodenum (HP:0002246) | 2.04337518 |
85 | Anophthalmia (HP:0000528) | 2.03426608 |
86 | Hemivertebrae (HP:0002937) | 2.02838099 |
87 | Dysmetria (HP:0001310) | 2.02780740 |
88 | Optic nerve hypoplasia (HP:0000609) | 2.02761608 |
89 | Cerebral edema (HP:0002181) | 2.01990140 |
90 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.99638356 |
91 | Bifid tongue (HP:0010297) | 1.99358558 |
92 | Split foot (HP:0001839) | 1.98455483 |
93 | Degeneration of anterior horn cells (HP:0002398) | 1.97942482 |
94 | Abnormality of the anterior horn cell (HP:0006802) | 1.97942482 |
95 | Abnormality of chromosome stability (HP:0003220) | 1.97443813 |
96 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.97101159 |
97 | Cerebral hemorrhage (HP:0001342) | 1.96222906 |
98 | Urinary urgency (HP:0000012) | 1.94965637 |
99 | Embryonal renal neoplasm (HP:0011794) | 1.94699314 |
100 | Progressive inability to walk (HP:0002505) | 1.94205539 |
101 | Sensory axonal neuropathy (HP:0003390) | 1.93100486 |
102 | Scanning speech (HP:0002168) | 1.93088139 |
103 | X-linked dominant inheritance (HP:0001423) | 1.92282986 |
104 | Abnormality of midbrain morphology (HP:0002418) | 1.90615553 |
105 | Molar tooth sign on MRI (HP:0002419) | 1.90615553 |
106 | Anxiety (HP:0000739) | 1.90310869 |
107 | Hypothermia (HP:0002045) | 1.89674784 |
108 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.88780982 |
109 | Preaxial hand polydactyly (HP:0001177) | 1.88740866 |
110 | Peripheral hypomyelination (HP:0007182) | 1.87045223 |
111 | Increased intramyocellular lipid droplets (HP:0012240) | 1.86203223 |
112 | Esophageal atresia (HP:0002032) | 1.85066188 |
113 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.84458931 |
114 | Lactic acidosis (HP:0003128) | 1.84414193 |
115 | Abnormality of the labia minora (HP:0012880) | 1.84115515 |
116 | Hypomagnesemia (HP:0002917) | 1.84046747 |
117 | Sloping forehead (HP:0000340) | 1.83984342 |
118 | Increased serum lactate (HP:0002151) | 1.83890895 |
119 | Medulloblastoma (HP:0002885) | 1.82755672 |
120 | Pancreatic cysts (HP:0001737) | 1.82493141 |
121 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.81985323 |
122 | Hypoplastic female external genitalia (HP:0012815) | 1.81261565 |
123 | Febrile seizures (HP:0002373) | 1.81260833 |
124 | Psychosis (HP:0000709) | 1.80493634 |
125 | Generalized myoclonic seizures (HP:0002123) | 1.79424301 |
126 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.77883876 |
127 | Ankle clonus (HP:0011448) | 1.77871521 |
128 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.76871944 |
129 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.76871944 |
130 | Autoamputation (HP:0001218) | 1.76821829 |
131 | Postaxial hand polydactyly (HP:0001162) | 1.76745852 |
132 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.76058305 |
133 | CNS demyelination (HP:0007305) | 1.75170680 |
134 | 3-Methylglutaconic aciduria (HP:0003535) | 1.74820854 |
135 | Pancreatic fibrosis (HP:0100732) | 1.74690409 |
136 | Poor suck (HP:0002033) | 1.74521330 |
137 | Esotropia (HP:0000565) | 1.73646430 |
138 | Inability to walk (HP:0002540) | 1.73638193 |
139 | Exercise intolerance (HP:0003546) | 1.73405051 |
140 | Abnormal lung lobation (HP:0002101) | 1.72585974 |
141 | Lissencephaly (HP:0001339) | 1.72583224 |
142 | Glioma (HP:0009733) | 1.70860259 |
143 | Poor coordination (HP:0002370) | 1.70363990 |
144 | Renal hypoplasia (HP:0000089) | 1.70073405 |
145 | Specific learning disability (HP:0001328) | 1.69733085 |
146 | Myelomeningocele (HP:0002475) | 1.69503963 |
147 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.69060608 |
148 | Absent/shortened dynein arms (HP:0200106) | 1.69060608 |
149 | Hyperglycinemia (HP:0002154) | 1.68919177 |
150 | Absent radius (HP:0003974) | 1.67828565 |
151 | Maternal diabetes (HP:0009800) | 1.67825864 |
152 | Supernumerary spleens (HP:0009799) | 1.67432311 |
153 | Labial hypoplasia (HP:0000066) | 1.67163065 |
154 | Drooling (HP:0002307) | 1.66059349 |
155 | Anencephaly (HP:0002323) | 1.65504014 |
156 | Chromsome breakage (HP:0040012) | 1.65351000 |
157 | Median cleft lip (HP:0000161) | 1.64805110 |
158 | Absent forearm bone (HP:0003953) | 1.63751644 |
159 | Aplasia involving forearm bones (HP:0009822) | 1.63751644 |
160 | Action tremor (HP:0002345) | 1.63667077 |
161 | Aqueductal stenosis (HP:0002410) | 1.63401927 |
162 | Sclerocornea (HP:0000647) | 1.62967823 |
163 | Gastrointestinal atresia (HP:0002589) | 1.62290474 |
164 | Short tibia (HP:0005736) | 1.61261409 |
165 | Dandy-Walker malformation (HP:0001305) | 1.61137244 |
166 | Rhabdomyosarcoma (HP:0002859) | 1.61064200 |
167 | Holoprosencephaly (HP:0001360) | 1.60083152 |
168 | Micropenis (HP:0000054) | 1.58838012 |
169 | Postaxial foot polydactyly (HP:0001830) | 1.58689390 |
170 | Abnormality of the lower motor neuron (HP:0002366) | 1.58586697 |
171 | Missing ribs (HP:0000921) | 1.56298892 |
172 | Amyotrophic lateral sclerosis (HP:0007354) | 1.55551046 |
173 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.54963737 |
174 | Triphalangeal thumb (HP:0001199) | 1.53664002 |
175 | Papillary thyroid carcinoma (HP:0002895) | 1.53659185 |
176 | Pendular nystagmus (HP:0012043) | 1.52344414 |
177 | Astrocytoma (HP:0009592) | 1.50239802 |
178 | Abnormality of the astrocytes (HP:0100707) | 1.50239802 |
179 | Horseshoe kidney (HP:0000085) | 1.49282094 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 4.83420549 |
2 | MAP3K12 | 3.79502499 |
3 | PNCK | 2.87126383 |
4 | OXSR1 | 2.69555796 |
5 | STK39 | 2.55584885 |
6 | WEE1 | 2.23920999 |
7 | CASK | 2.22245973 |
8 | MAP3K4 | 2.13468423 |
9 | TRIM28 | 2.09445580 |
10 | SRPK1 | 2.02561662 |
11 | MKNK2 | 1.96694061 |
12 | STK16 | 1.95263504 |
13 | PBK | 1.94035993 |
14 | CDK19 | 1.92704836 |
15 | EPHA4 | 1.88994638 |
16 | NTRK3 | 1.87976344 |
17 | PLK4 | 1.83867012 |
18 | UHMK1 | 1.82438601 |
19 | MAPKAPK5 | 1.82174685 |
20 | MAP2K7 | 1.80451648 |
21 | MINK1 | 1.77885430 |
22 | TESK2 | 1.75795867 |
23 | CCNB1 | 1.70841386 |
24 | TSSK6 | 1.69209261 |
25 | PLK2 | 1.64657885 |
26 | MAP3K9 | 1.62018280 |
27 | EIF2AK3 | 1.61811195 |
28 | MST4 | 1.58350296 |
29 | CSNK1G3 | 1.50350837 |
30 | TNIK | 1.49474905 |
31 | ARAF | 1.43797543 |
32 | MARK1 | 1.39771975 |
33 | PLK3 | 1.38577804 |
34 | FGR | 1.37175084 |
35 | BRSK1 | 1.36229365 |
36 | RIPK4 | 1.34315904 |
37 | GRK5 | 1.28719443 |
38 | WNK4 | 1.28302806 |
39 | BCR | 1.27433185 |
40 | GRK6 | 1.26749604 |
41 | MAPK13 | 1.26457511 |
42 | FES | 1.25851092 |
43 | VRK1 | 1.25220756 |
44 | BRSK2 | 1.25024177 |
45 | NTRK2 | 1.20084333 |
46 | CSNK1G2 | 1.17860956 |
47 | PRKD3 | 1.15971149 |
48 | MAP2K4 | 1.13298591 |
49 | CDC7 | 1.12703429 |
50 | CDK14 | 1.08624251 |
51 | ZAK | 1.05815109 |
52 | CDK18 | 1.04246173 |
53 | NME1 | 1.03326138 |
54 | CDK15 | 1.02003002 |
55 | ERBB3 | 0.99591427 |
56 | NEK1 | 0.98639592 |
57 | PDK2 | 0.97000658 |
58 | BRAF | 0.96548653 |
59 | EPHB2 | 0.95073898 |
60 | MAP4K2 | 0.94102613 |
61 | AURKB | 0.91609190 |
62 | CDK11A | 0.90399325 |
63 | CAMK2B | 0.89787478 |
64 | VRK2 | 0.87643782 |
65 | GRK7 | 0.87610993 |
66 | AURKA | 0.87347303 |
67 | LIMK1 | 0.86594083 |
68 | EIF2AK2 | 0.86230090 |
69 | WNK3 | 0.84701976 |
70 | CSNK1G1 | 0.83926357 |
71 | KSR2 | 0.83251803 |
72 | NUAK1 | 0.80944504 |
73 | ADRBK2 | 0.80458371 |
74 | ERBB4 | 0.80110902 |
75 | STK38L | 0.78439101 |
76 | DAPK1 | 0.76557129 |
77 | CAMK2A | 0.75395769 |
78 | CDK5 | 0.74087958 |
79 | NTRK1 | 0.73843928 |
80 | STK3 | 0.72163474 |
81 | PLK1 | 0.72073777 |
82 | TTK | 0.71724475 |
83 | PRKCG | 0.71018080 |
84 | MELK | 0.70906735 |
85 | CLK1 | 0.68525945 |
86 | CSNK1A1L | 0.68139999 |
87 | ATR | 0.67232985 |
88 | LATS2 | 0.66267662 |
89 | PINK1 | 0.66159111 |
90 | SGK223 | 0.62857489 |
91 | SGK494 | 0.62857489 |
92 | NEK6 | 0.62199467 |
93 | KSR1 | 0.62040042 |
94 | ROCK2 | 0.59553220 |
95 | BMPR1B | 0.59510064 |
96 | BMPR2 | 0.53053833 |
97 | PKN1 | 0.52961084 |
98 | DYRK3 | 0.52609775 |
99 | PRPF4B | 0.52560243 |
100 | MAP3K13 | 0.51040203 |
101 | SYK | 0.50433863 |
102 | EIF2AK1 | 0.50293618 |
103 | PAK3 | 0.49600139 |
104 | STK10 | 0.48437386 |
105 | ADRBK1 | 0.48293966 |
106 | DYRK1A | 0.48115771 |
107 | ATM | 0.46638573 |
108 | TAF1 | 0.45874600 |
109 | MKNK1 | 0.43739930 |
110 | MAP3K6 | 0.41008998 |
111 | DYRK2 | 0.41004718 |
112 | NEK2 | 0.40294927 |
113 | PAK6 | 0.39023240 |
114 | CDK3 | 0.37841428 |
115 | ERBB2 | 0.36445905 |
116 | TNK2 | 0.35395979 |
117 | PRKCQ | 0.34484559 |
118 | FGFR1 | 0.34254415 |
119 | CAMK2D | 0.33807646 |
120 | PTK2B | 0.33462360 |
121 | CDK8 | 0.33404027 |
122 | CSNK1E | 0.33363805 |
123 | CHEK1 | 0.32222304 |
124 | ALK | 0.32116889 |
125 | PRKCI | 0.31920436 |
126 | FYN | 0.30402907 |
127 | RPS6KA4 | 0.29845351 |
128 | YES1 | 0.25444582 |
129 | CAMK2G | 0.25151456 |
130 | MAPK4 | 0.25061134 |
131 | CDK1 | 0.24721532 |
132 | PRKCE | 0.24704304 |
133 | LCK | 0.24455170 |
134 | CHEK2 | 0.23976144 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.40791627 |
2 | Parkinsons disease_Homo sapiens_hsa05012 | 3.64569804 |
3 | Nicotine addiction_Homo sapiens_hsa05033 | 3.55003038 |
4 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 3.34556512 |
5 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.95775515 |
6 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.93671183 |
7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.79177685 |
8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.56865272 |
9 | Proteasome_Homo sapiens_hsa03050 | 2.54733922 |
10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.45234121 |
11 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.21362630 |
12 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.19097464 |
13 | GABAergic synapse_Homo sapiens_hsa04727 | 2.09128646 |
14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.96154669 |
15 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.86297023 |
16 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.76821538 |
17 | Morphine addiction_Homo sapiens_hsa05032 | 1.75895760 |
18 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.73234839 |
19 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.69509520 |
20 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.67601440 |
21 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.61467703 |
22 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.60732013 |
23 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.59921095 |
24 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.59600726 |
25 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.57788564 |
26 | Long-term potentiation_Homo sapiens_hsa04720 | 1.51999077 |
27 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.51812626 |
28 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.50611972 |
29 | Circadian entrainment_Homo sapiens_hsa04713 | 1.41096860 |
30 | Phototransduction_Homo sapiens_hsa04744 | 1.38931779 |
31 | Ribosome_Homo sapiens_hsa03010 | 1.36343026 |
32 | Long-term depression_Homo sapiens_hsa04730 | 1.34305624 |
33 | Olfactory transduction_Homo sapiens_hsa04740 | 1.34215318 |
34 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.33539319 |
35 | Base excision repair_Homo sapiens_hsa03410 | 1.32118438 |
36 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.31322206 |
37 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.30805488 |
38 | Protein export_Homo sapiens_hsa03060 | 1.28139694 |
39 | Taste transduction_Homo sapiens_hsa04742 | 1.27946816 |
40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.26123974 |
41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.22740000 |
42 | RNA polymerase_Homo sapiens_hsa03020 | 1.18513864 |
43 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.18033625 |
44 | Cocaine addiction_Homo sapiens_hsa05030 | 1.16695774 |
45 | Salivary secretion_Homo sapiens_hsa04970 | 1.15862871 |
46 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.14617895 |
47 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.11898712 |
48 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.10468370 |
49 | Renin secretion_Homo sapiens_hsa04924 | 1.09281580 |
50 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.07952492 |
51 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.07189960 |
52 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.07035919 |
53 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.06862723 |
54 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.03880991 |
55 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.01487901 |
56 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.99709966 |
57 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.98553843 |
58 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.96946687 |
59 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.96237690 |
60 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.93864889 |
61 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.93650544 |
62 | Mismatch repair_Homo sapiens_hsa03430 | 0.91157500 |
63 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.90162079 |
64 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.88777088 |
65 | Gap junction_Homo sapiens_hsa04540 | 0.88308754 |
66 | Phagosome_Homo sapiens_hsa04145 | 0.88038774 |
67 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.84516431 |
68 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.83910737 |
69 | Spliceosome_Homo sapiens_hsa03040 | 0.78791159 |
70 | Alcoholism_Homo sapiens_hsa05034 | 0.78540627 |
71 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.78451051 |
72 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.78113329 |
73 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.75028655 |
74 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.74777450 |
75 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.71838671 |
76 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.71533744 |
77 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.71270147 |
78 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.71005059 |
79 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.70636971 |
80 | Axon guidance_Homo sapiens_hsa04360 | 0.69559812 |
81 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.68545742 |
82 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.67237301 |
83 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.67191565 |
84 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.66773330 |
85 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.64829585 |
86 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.64624323 |
87 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.63712665 |
88 | Cell cycle_Homo sapiens_hsa04110 | 0.63159977 |
89 | Peroxisome_Homo sapiens_hsa04146 | 0.61653820 |
90 | Homologous recombination_Homo sapiens_hsa03440 | 0.58546154 |
91 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.58452210 |
92 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.57075511 |
93 | Carbon metabolism_Homo sapiens_hsa01200 | 0.56812295 |
94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.56530281 |
95 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.54137678 |
96 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.52174641 |
97 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.49936115 |
98 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.46728254 |
99 | Basal transcription factors_Homo sapiens_hsa03022 | 0.46265907 |
100 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45234346 |
101 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.44982997 |
102 | DNA replication_Homo sapiens_hsa03030 | 0.44775525 |
103 | RNA degradation_Homo sapiens_hsa03018 | 0.44453284 |
104 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.43160353 |
105 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.42796608 |
106 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.42677359 |
107 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.41434996 |
108 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.41230127 |
109 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.41149086 |
110 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.40663541 |
111 | Histidine metabolism_Homo sapiens_hsa00340 | 0.40214269 |
112 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.38886604 |
113 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.38788170 |
114 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.38650434 |
115 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.38515608 |
116 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.38124176 |
117 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.37357126 |
118 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.33905926 |
119 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.33477339 |
120 | Purine metabolism_Homo sapiens_hsa00230 | 0.33004915 |
121 | RNA transport_Homo sapiens_hsa03013 | 0.29098607 |
122 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.29073094 |
123 | Insulin secretion_Homo sapiens_hsa04911 | 0.27735970 |
124 | Melanogenesis_Homo sapiens_hsa04916 | 0.27270125 |
125 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.27148928 |
126 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.27145433 |
127 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.26914453 |
128 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.25204260 |
129 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.24968321 |
130 | Asthma_Homo sapiens_hsa05310 | 0.22431298 |
131 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.22379666 |
132 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.20891665 |
133 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.20702454 |
134 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.18609730 |
135 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.18165751 |
136 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.16356201 |
137 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.15444742 |