ARL6IP6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)5.46261618
2DNA strand elongation (GO:0022616)5.25907382
3DNA replication initiation (GO:0006270)5.16485313
4telomere maintenance via semi-conservative replication (GO:0032201)5.09479818
5DNA unwinding involved in DNA replication (GO:0006268)4.97064501
6DNA replication checkpoint (GO:0000076)4.72886600
7telomere maintenance via recombination (GO:0000722)4.62834002
8DNA ligation (GO:0006266)4.60199667
9mitotic recombination (GO:0006312)4.44101889
10chromatin remodeling at centromere (GO:0031055)4.22466261
11CENP-A containing nucleosome assembly (GO:0034080)4.21615579
12establishment of viral latency (GO:0019043)4.21445467
13DNA replication-dependent nucleosome assembly (GO:0006335)4.19305243
14DNA replication-dependent nucleosome organization (GO:0034723)4.19305243
15nucleotide-excision repair, DNA gap filling (GO:0006297)4.14831589
16protein localization to kinetochore (GO:0034501)4.03748744
17telomere maintenance via telomere lengthening (GO:0010833)4.02254112
18regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.00676291
19kinetochore organization (GO:0051383)3.94307675
20DNA double-strand break processing (GO:0000729)3.91286521
21DNA replication-independent nucleosome organization (GO:0034724)3.90364473
22DNA replication-independent nucleosome assembly (GO:0006336)3.90364473
23ribosomal small subunit assembly (GO:0000028)3.86729147
24sister chromatid segregation (GO:0000819)3.85706184
25DNA deamination (GO:0045006)3.82275284
26proteasome assembly (GO:0043248)3.80753618
27mitotic metaphase plate congression (GO:0007080)3.79701434
28DNA topological change (GO:0006265)3.69648438
29protein localization to chromosome, centromeric region (GO:0071459)3.67775995
30protein neddylation (GO:0045116)3.65304642
31maturation of SSU-rRNA (GO:0030490)3.64035169
32negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.62250631
33nuclear pore organization (GO:0006999)3.61834080
34cullin deneddylation (GO:0010388)3.61552206
35histone exchange (GO:0043486)3.61434193
36nucleobase biosynthetic process (GO:0046112)3.58568039
37mitotic nuclear envelope disassembly (GO:0007077)3.57183175
38regulation of double-strand break repair via homologous recombination (GO:0010569)3.56029878
39regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.53789463
40kinetochore assembly (GO:0051382)3.52316489
41attachment of spindle microtubules to kinetochore (GO:0008608)3.49560641
42deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.47910533
43anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.47158496
44formation of translation preinitiation complex (GO:0001731)3.46279585
45translesion synthesis (GO:0019985)3.43398946
46folic acid-containing compound biosynthetic process (GO:0009396)3.42676798
47metaphase plate congression (GO:0051310)3.41693141
48nuclear pore complex assembly (GO:0051292)3.40548218
49replication fork processing (GO:0031297)3.39567414
50protein deneddylation (GO:0000338)3.39178632
51purine nucleobase biosynthetic process (GO:0009113)3.32321823
52pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.31948155
53nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.31896699
54viral transcription (GO:0019083)3.31634684
55mitotic spindle checkpoint (GO:0071174)3.29029932
56translational termination (GO:0006415)3.27605590
57positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.26851487
58nuclear envelope disassembly (GO:0051081)3.26635780
59membrane disassembly (GO:0030397)3.26635780
60negative regulation of ligase activity (GO:0051352)3.25201089
61negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.25201089
62exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.24453115
63mitotic chromosome condensation (GO:0007076)3.22935658
64telomere maintenance (GO:0000723)3.21375248
65regulation of mitotic spindle checkpoint (GO:1903504)3.21308293
66regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.21308293
67mitotic G2/M transition checkpoint (GO:0044818)3.20175381
68telomere organization (GO:0032200)3.20034968
69DNA catabolic process, exonucleolytic (GO:0000738)3.16903745
70base-excision repair (GO:0006284)3.15757256
71meiotic chromosome segregation (GO:0045132)3.15742053
72spliceosomal snRNP assembly (GO:0000387)3.15376296
73IMP metabolic process (GO:0046040)3.14899781
74histone mRNA metabolic process (GO:0008334)3.12584663
75regulation of nuclear cell cycle DNA replication (GO:0033262)3.12379623
76establishment of chromosome localization (GO:0051303)3.09005645
77IMP biosynthetic process (GO:0006188)3.08925743
78mitotic sister chromatid cohesion (GO:0007064)3.08867738
79intra-S DNA damage checkpoint (GO:0031573)3.08202784
80somatic diversification of immune receptors via somatic mutation (GO:0002566)3.07785882
81somatic hypermutation of immunoglobulin genes (GO:0016446)3.07785882
82postreplication repair (GO:0006301)3.07749805
83regulation of helicase activity (GO:0051095)3.07636208
84regulation of mitotic sister chromatid separation (GO:0010965)3.07531834
85regulation of mitotic sister chromatid segregation (GO:0033047)3.07531834
86regulation of sister chromatid segregation (GO:0033045)3.07531834
87chromatin assembly or disassembly (GO:0006333)3.07195735
88maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.06418349
89ribosome biogenesis (GO:0042254)3.05104449
90ribosomal small subunit biogenesis (GO:0042274)3.03988918
91L-serine metabolic process (GO:0006563)3.03160438
92negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.02272688
93ribonucleoprotein complex biogenesis (GO:0022613)3.01822768
94mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.01326622
95establishment of protein localization to mitochondrial membrane (GO:0090151)3.01245107
96ATP-dependent chromatin remodeling (GO:0043044)3.00892020
97establishment of integrated proviral latency (GO:0075713)3.00737345
98translational elongation (GO:0006414)3.00685185
99DNA duplex unwinding (GO:0032508)3.00632796
100DNA geometric change (GO:0032392)3.00404792
101non-recombinational repair (GO:0000726)3.00382457
102double-strand break repair via nonhomologous end joining (GO:0006303)3.00382457
103mismatch repair (GO:0006298)2.99421624
104deoxyribonucleotide biosynthetic process (GO:0009263)2.99264403
105pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.98431436
106microtubule depolymerization (GO:0007019)2.97936761
107transcription-coupled nucleotide-excision repair (GO:0006283)2.96911790
108translational initiation (GO:0006413)2.96353355
109negative regulation of RNA splicing (GO:0033119)2.96179124
110sequestering of actin monomers (GO:0042989)2.95763695
111negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.94985963
112negative regulation of sister chromatid segregation (GO:0033046)2.94985963
113negative regulation of mitotic sister chromatid separation (GO:2000816)2.94985963
114negative regulation of mitotic sister chromatid segregation (GO:0033048)2.94985963
115negative regulation of chromosome segregation (GO:0051985)2.94691019
116SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.94416166
117ribosomal large subunit biogenesis (GO:0042273)2.93414238
118cell cycle G1/S phase transition (GO:0044843)2.92960149
119G1/S transition of mitotic cell cycle (GO:0000082)2.92960149
120chromosome segregation (GO:0007059)2.92604284
121DNA replication (GO:0006260)2.89911781
122protein K6-linked ubiquitination (GO:0085020)2.89845252
123regulation of centrosome cycle (GO:0046605)2.89395438
124rRNA processing (GO:0006364)2.89207663
125protein localization to chromosome (GO:0034502)2.88807233
126negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.87024026
127nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.86961576
128mitotic sister chromatid segregation (GO:0000070)2.86870320
129spindle assembly checkpoint (GO:0071173)2.86418259
130cotranslational protein targeting to membrane (GO:0006613)2.86330831
131spindle checkpoint (GO:0031577)2.85915138
132termination of RNA polymerase II transcription (GO:0006369)2.85860274
133regulation of mitotic metaphase/anaphase transition (GO:0030071)2.84331442
134protein targeting to ER (GO:0045047)2.84242627
135regulation of chromosome segregation (GO:0051983)2.83277999
136mitotic spindle assembly checkpoint (GO:0007094)2.81165559
137rRNA metabolic process (GO:0016072)2.79192725
138regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.78421184
139DNA conformation change (GO:0071103)2.78016725
140pseudouridine synthesis (GO:0001522)2.76213729
141regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.75388781
142negative regulation of mRNA processing (GO:0050686)2.74433807

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* MYC_18555785_ChIP-Seq_MESCs_Mouse4.18981919
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.11825582
3* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.06260495
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.47049576
5* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.33844126
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.93813112
7MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.88200433
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.77494007
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.68149365
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.67162180
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.67063127
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.64913106
13* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.40628584
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.36832573
15AR_21909140_ChIP-Seq_LNCAP_Human2.35777621
16NELFA_20434984_ChIP-Seq_ESCs_Mouse2.35648462
17* E2F1_21310950_ChIP-Seq_MCF-7_Human2.30679267
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.30453153
19ETS1_20019798_ChIP-Seq_JURKAT_Human2.30374013
20* XRN2_22483619_ChIP-Seq_HELA_Human2.22934324
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.18410127
22* VDR_23849224_ChIP-Seq_CD4+_Human2.15807788
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.13941135
24E2F7_22180533_ChIP-Seq_HELA_Human10.5626705
25* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.96892751
26* FOXP3_21729870_ChIP-Seq_TREG_Human1.91775687
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.89217294
28DCP1A_22483619_ChIP-Seq_HELA_Human1.88867508
29SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.88625135
30PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.87623917
31* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.86388709
32EGR1_19374776_ChIP-ChIP_THP-1_Human1.84852719
33SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.83646190
34TTF2_22483619_ChIP-Seq_HELA_Human1.83073736
35* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.77229886
36GABP_19822575_ChIP-Seq_HepG2_Human1.72326220
37* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.69309303
38FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.68462251
39MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.68403103
40ELK1_19687146_ChIP-ChIP_HELA_Human1.65723132
41HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.63966561
42EWS_26573619_Chip-Seq_HEK293_Human1.62980186
43* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.60704092
44* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.60607588
45TP63_19390658_ChIP-ChIP_HaCaT_Human1.59546922
46IGF1R_20145208_ChIP-Seq_DFB_Human1.56085568
47HOXB4_20404135_ChIP-ChIP_EML_Mouse1.55234018
48NANOG_18555785_ChIP-Seq_MESCs_Mouse1.53211340
49MYC_22102868_ChIP-Seq_BL_Human1.51010993
50POU5F1_16153702_ChIP-ChIP_HESCs_Human1.50061735
51RBPJ_22232070_ChIP-Seq_NCS_Mouse1.49077267
52NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.47748415
53IRF1_19129219_ChIP-ChIP_H3396_Human1.47085726
54ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.44712518
55THAP11_20581084_ChIP-Seq_MESCs_Mouse1.43507979
56YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.42197739
57SOX2_16153702_ChIP-ChIP_HESCs_Human1.41808968
58ERG_20887958_ChIP-Seq_HPC-7_Mouse1.41091558
59ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.36270816
60CIITA_25753668_ChIP-Seq_RAJI_Human1.35739743
61NANOG_16153702_ChIP-ChIP_HESCs_Human1.33612527
62SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.33513046
63KDM5A_27292631_Chip-Seq_BREAST_Human1.29696177
64HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.27580602
65SRF_21415370_ChIP-Seq_HL-1_Mouse1.27323458
66E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.25616651
67* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.25105472
68FUS_26573619_Chip-Seq_HEK293_Human1.24357586
69CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.23753354
70E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.22585699
71YY1_21170310_ChIP-Seq_MESCs_Mouse1.22196688
72FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.19971504
73NOTCH1_21737748_ChIP-Seq_TLL_Human1.17869362
74CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.14942766
75PADI4_21655091_ChIP-ChIP_MCF-7_Human1.13496136
76SOX2_18555785_ChIP-Seq_MESCs_Mouse1.13205498
77POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.08683392
78KLF4_18555785_ChIP-Seq_MESCs_Mouse1.07657986
79SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.06257662
80POU3F2_20337985_ChIP-ChIP_501MEL_Human1.05696960
81KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.04625069
82GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.02029430
83TFEB_21752829_ChIP-Seq_HELA_Human1.01905500
84NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.00647035
85CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99676658
86ZNF274_21170338_ChIP-Seq_K562_Hela0.99615718
87MYC_18940864_ChIP-ChIP_HL60_Human0.99130185
88STAT3_1855785_ChIP-Seq_MESCs_Mouse0.97984169
89SPI1_23547873_ChIP-Seq_NB4_Human0.96602174
90DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.95680784
91ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95522224
92SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.92831310
93PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.92229848
94SOX17_20123909_ChIP-Seq_XEN_Mouse0.90670263
95CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.88984653
96* VDR_21846776_ChIP-Seq_THP-1_Human0.88962477
97NANOG_21062744_ChIP-ChIP_HESCs_Human0.87458418
98TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.87326840
99SALL1_21062744_ChIP-ChIP_HESCs_Human0.85299964
100CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.82042287
101IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.80725694
102BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.80613493
103TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.80351634
104POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.79983264
105TAF15_26573619_Chip-Seq_HEK293_Human0.76732405
106SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.74671977
107CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.74665496
108CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.74554220
109CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.73964956
110FLI1_27457419_Chip-Seq_LIVER_Mouse0.73194066
111DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.72660108
112NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.71056016
113FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.70873362
114SCL_19346495_ChIP-Seq_HPC-7_Human0.70006125
115PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.69305375
116ELK1_22589737_ChIP-Seq_MCF10A_Human0.69241193
117MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.67467244
118FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.66512984

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.72443620
2MP0010094_abnormal_chromosome_stability4.58489477
3MP0008057_abnormal_DNA_replication3.92366109
4MP0003111_abnormal_nucleus_morphology3.88569379
5MP0004957_abnormal_blastocyst_morpholog3.80476212
6MP0003077_abnormal_cell_cycle3.66992878
7MP0008058_abnormal_DNA_repair3.37015825
8MP0008007_abnormal_cellular_replicative2.91873350
9MP0001529_abnormal_vocalization2.59528224
10MP0008932_abnormal_embryonic_tissue2.52855317
11MP0003123_paternal_imprinting2.42728640
12MP0002396_abnormal_hematopoietic_system2.38382164
13MP0005394_taste/olfaction_phenotype2.34229597
14MP0005499_abnormal_olfactory_system2.34229597
15MP0008877_abnormal_DNA_methylation2.32992767
16MP0006054_spinal_hemorrhage2.13171198
17MP0010352_gastrointestinal_tract_polyps2.10713593
18MP0000350_abnormal_cell_proliferation2.05344685
19MP0003136_yellow_coat_color2.03533338
20MP0000490_abnormal_crypts_of1.99911598
21MP0001730_embryonic_growth_arrest1.93922092
22MP0003786_premature_aging1.70358772
23MP0006072_abnormal_retinal_apoptosis1.65085938
24MP0004808_abnormal_hematopoietic_stem1.56555803
25MP0001293_anophthalmia1.56007807
26MP0001697_abnormal_embryo_size1.55985248
27MP0005380_embryogenesis_phenotype1.52178148
28MP0001672_abnormal_embryogenesis/_devel1.52178148
29MP0002210_abnormal_sex_determination1.50783728
30MP0003122_maternal_imprinting1.49929314
31MP0006292_abnormal_olfactory_placode1.49202713
32MP0010307_abnormal_tumor_latency1.48209572
33MP0003221_abnormal_cardiomyocyte_apopto1.45276559
34MP0000313_abnormal_cell_death1.40139262
35MP0003984_embryonic_growth_retardation1.39662817
36MP0005084_abnormal_gallbladder_morpholo1.39518743
37MP0003121_genomic_imprinting1.38999085
38MP0005397_hematopoietic_system_phenotyp1.38814449
39MP0001545_abnormal_hematopoietic_system1.38814449
40MP0003567_abnormal_fetal_cardiomyocyte1.38061197
41MP0002233_abnormal_nose_morphology1.36824090
42MP0010030_abnormal_orbit_morphology1.36751628
43MP0002088_abnormal_embryonic_growth/wei1.35750935
44MP0002080_prenatal_lethality1.35688453
45MP0002085_abnormal_embryonic_tissue1.35607180
46MP0003763_abnormal_thymus_physiology1.35144715
47MP0002019_abnormal_tumor_incidence1.34598598
48MP0001929_abnormal_gametogenesis1.31721746
49MP0001145_abnormal_male_reproductive1.29428597
50MP0002234_abnormal_pharynx_morphology1.28332501
51MP0006035_abnormal_mitochondrial_morpho1.27605668
52MP0004197_abnormal_fetal_growth/weight/1.25525925
53MP0002086_abnormal_extraembryonic_tissu1.24101885
54MP0002084_abnormal_developmental_patter1.21909971
55MP0002697_abnormal_eye_size1.17837930
56MP0003890_abnormal_embryonic-extraembry1.17246876
57MP0005076_abnormal_cell_differentiation1.17026757
58MP0000566_synostosis1.16783676
59MP0009333_abnormal_splenocyte_physiolog1.15780762
60MP0002398_abnormal_bone_marrow1.12813801
61MP0005253_abnormal_eye_physiology1.11214406
62MP0000653_abnormal_sex_gland1.10752748
63MP0005391_vision/eye_phenotype1.10514015
64MP0000703_abnormal_thymus_morphology1.10095302
65MP0003011_delayed_dark_adaptation1.06883198
66MP0002751_abnormal_autonomic_nervous1.06867692
67MP0000647_abnormal_sebaceous_gland1.05466163
68MP0001764_abnormal_homeostasis1.04337884
69MP0002102_abnormal_ear_morphology1.02334500
70MP0000372_irregular_coat_pigmentation1.02061144
71MP0002722_abnormal_immune_system0.96504160
72MP0003718_maternal_effect0.95731817
73MP0001119_abnormal_female_reproductive0.95418736
74MP0009053_abnormal_anal_canal0.95116856
75MP0002090_abnormal_vision0.94675840
76MP0000689_abnormal_spleen_morphology0.94109415
77MP0003315_abnormal_perineum_morphology0.92815359
78MP0002938_white_spotting0.90864190
79MP0008789_abnormal_olfactory_epithelium0.89485898
80MP0006036_abnormal_mitochondrial_physio0.88404690
81MP0002653_abnormal_ependyma_morphology0.87851452
82MP0003119_abnormal_digestive_system0.86277820
83MP0002009_preneoplasia0.85914602
84MP0005171_absent_coat_pigmentation0.85774901
85MP0000631_abnormal_neuroendocrine_gland0.85672361
86MP0002160_abnormal_reproductive_system0.84669276
87MP0002429_abnormal_blood_cell0.83786952
88MP0005248_abnormal_Harderian_gland0.83080748
89MP0004147_increased_porphyrin_level0.82051134
90MP0003698_abnormal_male_reproductive0.81829661
91MP0000049_abnormal_middle_ear0.81277392
92MP0001286_abnormal_eye_development0.81206145
93MP0003755_abnormal_palate_morphology0.80967674
94MP0001188_hyperpigmentation0.79596157
95MP0003861_abnormal_nervous_system0.78875698
96MP0003937_abnormal_limbs/digits/tail_de0.77896356
97MP0002092_abnormal_eye_morphology0.76683850
98MP0003385_abnormal_body_wall0.76554294
99MP0009278_abnormal_bone_marrow0.76549128
100MP0002163_abnormal_gland_morphology0.75645463
101MP0001853_heart_inflammation0.74130586
102MP0000778_abnormal_nervous_system0.72718057
103MP0003806_abnormal_nucleotide_metabolis0.72534762
104MP0003186_abnormal_redox_activity0.72315791
105MP0004133_heterotaxia0.72177178
106MP0005671_abnormal_response_to0.71944231
107MP0000428_abnormal_craniofacial_morphol0.71843908
108MP0000358_abnormal_cell_content/0.71622470
109MP0002132_abnormal_respiratory_system0.71480097
110MP0000537_abnormal_urethra_morphology0.70731060
111MP0008995_early_reproductive_senescence0.70542216
112MP0005075_abnormal_melanosome_morpholog0.70492869
113MP0000716_abnormal_immune_system0.70438358
114MP0001915_intracranial_hemorrhage0.70083427
115MP0009697_abnormal_copulation0.69914498
116MP0003656_abnormal_erythrocyte_physiolo0.69800991
117MP0000858_altered_metastatic_potential0.69669948
118MP0002638_abnormal_pupillary_reflex0.68909851
119MP0002282_abnormal_trachea_morphology0.68201404
120MP0000685_abnormal_immune_system0.66826586
121MP0002095_abnormal_skin_pigmentation0.66513685
122MP0005389_reproductive_system_phenotype0.65792059
123MP0005384_cellular_phenotype0.64844508
124MP0001346_abnormal_lacrimal_gland0.64545021
125MP0009672_abnormal_birth_weight0.64456092
126MP0002006_tumorigenesis0.64003646
127MP0005410_abnormal_fertilization0.63756617
128MP0005174_abnormal_tail_pigmentation0.63375508
129MP0001727_abnormal_embryo_implantation0.62955769
130MP0009703_decreased_birth_body0.62888504
131MP0000477_abnormal_intestine_morphology0.61862578
132MP0003941_abnormal_skin_development0.61714637
133MP0002111_abnormal_tail_morphology0.60805487
134MP0009379_abnormal_foot_pigmentation0.59679880
135MP0002161_abnormal_fertility/fecundity0.59555918

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.94804143
2Abnormality of cells of the erythroid lineage (HP:0012130)4.33530692
3Abnormal number of erythroid precursors (HP:0012131)4.28858966
4Reticulocytopenia (HP:0001896)4.26049653
5Breast hypoplasia (HP:0003187)3.63583480
6Chromsome breakage (HP:0040012)3.63455624
7Cortical dysplasia (HP:0002539)3.44041168
8Abnormality of chromosome stability (HP:0003220)3.42639349
9Chromosomal breakage induced by crosslinking agents (HP:0003221)3.42172624
10Colon cancer (HP:0003003)3.38736553
11Patellar aplasia (HP:0006443)3.25069177
12Selective tooth agenesis (HP:0001592)3.20025308
13Oral leukoplakia (HP:0002745)3.08004824
14Increased hepatocellular lipid droplets (HP:0006565)3.00355302
15Aplasia/Hypoplasia of the patella (HP:0006498)2.98768973
16Abnormality of the labia minora (HP:0012880)2.97656942
17Aplasia/Hypoplasia of the uvula (HP:0010293)2.94758141
18Meckel diverticulum (HP:0002245)2.93399837
1911 pairs of ribs (HP:0000878)2.89885452
20Aplastic anemia (HP:0001915)2.88041856
21Medulloblastoma (HP:0002885)2.88012846
22Acute necrotizing encephalopathy (HP:0006965)2.86488862
23Abnormality of the preputium (HP:0100587)2.83955335
24Abnormality of the ileum (HP:0001549)2.82027832
25Supernumerary spleens (HP:0009799)2.77380323
26Pallor (HP:0000980)2.69771340
27Septo-optic dysplasia (HP:0100842)2.68790400
28Acute encephalopathy (HP:0006846)2.66057355
29Absent thumb (HP:0009777)2.65844216
30Myelodysplasia (HP:0002863)2.61964431
31Abnormality of the anterior horn cell (HP:0006802)2.61786114
32Degeneration of anterior horn cells (HP:0002398)2.61786114
33Abnormal mitochondria in muscle tissue (HP:0008316)2.59984756
34Lipid accumulation in hepatocytes (HP:0006561)2.56864234
35Microvesicular hepatic steatosis (HP:0001414)2.56320437
36Atresia of the external auditory canal (HP:0000413)2.55862674
37Small intestinal stenosis (HP:0012848)2.55022112
38Duodenal stenosis (HP:0100867)2.55022112
39Mitochondrial inheritance (HP:0001427)2.54957056
40Microretrognathia (HP:0000308)2.52851750
41Impulsivity (HP:0100710)2.52444000
42Abnormality of the heme biosynthetic pathway (HP:0010472)2.51621398
43Hypoplastic pelvis (HP:0008839)2.49125328
44Ectopic kidney (HP:0000086)2.48694562
45Increased CSF lactate (HP:0002490)2.47752801
46Absent radius (HP:0003974)2.46086551
47Hyperglycinemia (HP:0002154)2.42384580
48Increased serum pyruvate (HP:0003542)2.42255459
49Hepatocellular necrosis (HP:0001404)2.41727593
50Absent forearm bone (HP:0003953)2.40777288
51Aplasia involving forearm bones (HP:0009822)2.40777288
52Abnormal number of incisors (HP:0011064)2.36812945
53Macrocytic anemia (HP:0001972)2.35905689
54Premature graying of hair (HP:0002216)2.33063705
55Bone marrow hypocellularity (HP:0005528)2.31601886
56Abnormal spermatogenesis (HP:0008669)2.30966529
57Neoplasm of the pancreas (HP:0002894)2.30782559
58Sloping forehead (HP:0000340)2.28163461
59Short middle phalanx of the 5th finger (HP:0004220)2.27436141
60Type I transferrin isoform profile (HP:0003642)2.24904891
61Abnormal lung lobation (HP:0002101)2.24069918
62Carpal bone hypoplasia (HP:0001498)2.21360883
63Pancreatic islet-cell hyperplasia (HP:0004510)2.20471516
64Abnormality of the duodenum (HP:0002246)2.20099854
65Triphalangeal thumb (HP:0001199)2.18743302
66Rough bone trabeculation (HP:0100670)2.16685637
67Hepatic necrosis (HP:0002605)2.15296383
68Cleft eyelid (HP:0000625)2.15161726
69Ependymoma (HP:0002888)2.13445756
70Progressive macrocephaly (HP:0004481)2.12135778
71Slender long bone (HP:0003100)2.09874283
72Postnatal microcephaly (HP:0005484)2.09808544
73Tracheoesophageal fistula (HP:0002575)2.09144817
743-Methylglutaconic aciduria (HP:0003535)2.08211158
75Renal Fanconi syndrome (HP:0001994)2.08071277
76Hemivertebrae (HP:0002937)2.07747696
77Aplasia/Hypoplasia of the sacrum (HP:0008517)2.05036024
78Abnormality of glycolysis (HP:0004366)2.04617384
79Agnosia (HP:0010524)2.04025896
80Increased nuchal translucency (HP:0010880)2.03591127
81Cellular immunodeficiency (HP:0005374)2.03403762
82Absent septum pellucidum (HP:0001331)2.03108313
83Nephroblastoma (Wilms tumor) (HP:0002667)2.02680699
84Increased serum lactate (HP:0002151)2.02457762
85Intestinal atresia (HP:0011100)2.02164640
86Proximal placement of thumb (HP:0009623)2.00932259
87Rhabdomyosarcoma (HP:0002859)1.99504865
88Lymphoma (HP:0002665)1.98094707
89Abnormality of the metopic suture (HP:0005556)1.96793346
90Duplicated collecting system (HP:0000081)1.96645358
91Abnormality of the carotid arteries (HP:0005344)1.95631287
92Hypoplasia of the radius (HP:0002984)1.95433743
93Aplasia/Hypoplasia of the sternum (HP:0006714)1.95218988
94Optic nerve coloboma (HP:0000588)1.95167842
95Deviation of the thumb (HP:0009603)1.93599963
96Missing ribs (HP:0000921)1.90098365
97Reduced antithrombin III activity (HP:0001976)1.89971417
98Embryonal renal neoplasm (HP:0011794)1.89750652
99Median cleft lip (HP:0000161)1.86428162
100Cerebral edema (HP:0002181)1.86390980
101Horseshoe kidney (HP:0000085)1.85356297
102Pancytopenia (HP:0001876)1.85233719
103Preaxial hand polydactyly (HP:0001177)1.85202988
104Oligodactyly (HP:0012165)1.84062783
105Abnormality of reticulocytes (HP:0004312)1.83868123
106Spastic diplegia (HP:0001264)1.81905680
107Overlapping toe (HP:0001845)1.81722277
108Clubbing of toes (HP:0100760)1.81189911
109IgM deficiency (HP:0002850)1.81104351
110Thrombocytosis (HP:0001894)1.80394776
111Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.80312541
112Abnormality of the renal collecting system (HP:0004742)1.78326014
113Muscle fiber atrophy (HP:0100295)1.76357602
114True hermaphroditism (HP:0010459)1.76179776
115Shoulder girdle muscle weakness (HP:0003547)1.75866711
116Abnormality of the septum pellucidum (HP:0007375)1.74425043
117Exertional dyspnea (HP:0002875)1.73806937
118Respiratory difficulties (HP:0002880)1.73557505
119Facial hemangioma (HP:0000329)1.73113428
120Facial cleft (HP:0002006)1.73079810
121Cafe-au-lait spot (HP:0000957)1.72719121
122Abnormality of serum amino acid levels (HP:0003112)1.72142999
123Short thumb (HP:0009778)1.71827673
124Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.71067602
125Short 4th metacarpal (HP:0010044)1.71067602
126Abdominal situs inversus (HP:0003363)1.71050085
127Abnormality of abdominal situs (HP:0011620)1.71050085
128Broad foot (HP:0001769)1.70632454
129Bifid tongue (HP:0010297)1.70083860
130Pendular nystagmus (HP:0012043)1.69644997
131Trismus (HP:0000211)1.69367751
132Lactic acidosis (HP:0003128)1.69039592
133Squamous cell carcinoma (HP:0002860)1.68620441
134Basal cell carcinoma (HP:0002671)1.67684899
135Volvulus (HP:0002580)1.67060192
136Type 2 muscle fiber atrophy (HP:0003554)1.67033493
137Ovarian neoplasm (HP:0100615)1.66809507
138Hypoplasia of the capital femoral epiphysis (HP:0003090)1.66695760
139Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.66463733
140Abnormal protein N-linked glycosylation (HP:0012347)1.66463733
141Abnormal protein glycosylation (HP:0012346)1.66463733
142Abnormal glycosylation (HP:0012345)1.66463733
143Atrophy/Degeneration involving motor neurons (HP:0007373)1.66130121
144Holoprosencephaly (HP:0001360)1.65083300
145Anophthalmia (HP:0000528)1.64544068
146Maternal diabetes (HP:0009800)1.64270225
147Glossoptosis (HP:0000162)1.64245085
148Irregular epiphyses (HP:0010582)1.63950705
149Gastrointestinal atresia (HP:0002589)1.62888694
150Stenosis of the external auditory canal (HP:0000402)1.62838424
151Multiple enchondromatosis (HP:0005701)1.62613060
152Neoplasm of the colon (HP:0100273)1.62341036
153Embryonal neoplasm (HP:0002898)1.61510844
154Congenital primary aphakia (HP:0007707)1.61021301

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.77885670
2WEE14.20193159
3BUB13.59592267
4EIF2AK13.38594316
5ACVR1B3.32108408
6VRK22.91198504
7NEK22.67492598
8SRPK12.46332407
9BRSK22.33112149
10EIF2AK32.32055705
11DYRK32.14560062
12MAP4K22.09712700
13MKNK12.06868850
14PLK42.06095889
15STK161.97043092
16PASK1.96353096
17TTK1.95394775
18TLK11.94276902
19VRK11.92801635
20RPS6KA41.88586879
21PLK11.84452269
22CDK71.83102425
23ATR1.75497965
24TRIM281.74739846
25BCR1.73042266
26NEK11.70443627
27MKNK21.68004946
28NUAK11.66766057
29NME21.62457243
30CDK191.58057358
31CDK121.55136509
32AURKB1.53714416
33CHEK21.48608845
34MAP3K101.43689450
35RPS6KB21.43151389
36CDK81.38416955
37SCYL21.37958890
38WNK31.37664719
39BRSK11.37360317
40CDK41.34230563
41TAF11.31631364
42STK101.22514967
43CSNK1G11.16605421
44TESK21.15112546
45MAP3K81.14778932
46CCNB11.14687078
47PLK31.14036782
48CHEK11.14022546
49TGFBR11.13117450
50BMPR1B1.11087702
51PIM11.11019693
52STK41.06703015
53CSNK1G31.06687491
54TNIK1.06599591
55AURKA1.03153846
56PIM21.02933033
57MAPKAPK31.00215908
58TSSK60.97636265
59EEF2K0.93739187
60CSNK1G20.93541978
61NME10.92283253
62ATM0.91869408
63FLT30.89175649
64YES10.89100888
65PBK0.87924407
66PAK40.87374664
67MAP2K70.85597673
68EIF2AK20.84383577
69CSNK1A1L0.84210071
70PLK20.83949785
71MELK0.81923046
72STK30.79735857
73CDK30.76807995
74CDK20.73568394
75TESK10.73039424
76BRD40.72537949
77MAP3K40.71048739
78MST40.70883741
79BRAF0.69505819
80KDR0.68415988
81EPHB20.67635344
82CSNK2A10.66426025
83MAP4K10.62848133
84CDK60.62258611
85LRRK20.62201046
86ERBB30.59452483
87CSNK2A20.59019281
88CDK140.58505124
89JAK30.58250593
90MARK30.57742935
91FGFR10.57717294
92ZAK0.56939817
93CDK10.55635412
94NLK0.54980229
95RPS6KA50.54859671
96BTK0.53952591
97MAP2K30.49248000
98CDK180.49135752
99TEC0.47786174
100CDK11A0.46958605
101TAOK20.46913614
102EPHA30.44410749
103PNCK0.44340796
104CDK150.44026484
105CLK10.43008969
106PAK10.41526749
107IRAK40.40840372
108DYRK1B0.38152801
109DYRK20.37829054
110NEK90.37271990
111CDK90.36483212
112MAPK110.36040766
113KSR10.35495635
114LIMK10.35486826
115RAF10.35152589
116CHUK0.33847197
117STK38L0.33798417
118MAP3K30.33746231
119ERBB40.33730704
120LATS10.32496736
121BCKDK0.31161554
122MINK10.29082681
123AKT10.27333846
124EPHA20.26907150
125AKT20.26361618
126KIT0.25266475
127PRKDC0.24570643
128MAP3K110.23517376
129TYK20.22894509
130LYN0.22503240
131ILK0.21142794
132PRKCI0.20464978

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.59865539
2Mismatch repair_Homo sapiens_hsa034304.44983493
3Spliceosome_Homo sapiens_hsa030403.26352801
4Homologous recombination_Homo sapiens_hsa034403.24379056
5Base excision repair_Homo sapiens_hsa034103.14941464
6Ribosome_Homo sapiens_hsa030103.12168196
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.08111410
8Cell cycle_Homo sapiens_hsa041103.04556635
9Nucleotide excision repair_Homo sapiens_hsa034202.87978322
10RNA transport_Homo sapiens_hsa030132.81107069
11Proteasome_Homo sapiens_hsa030502.55236723
12Fanconi anemia pathway_Homo sapiens_hsa034602.54837214
13RNA polymerase_Homo sapiens_hsa030202.47801464
14Pyrimidine metabolism_Homo sapiens_hsa002402.41841559
15One carbon pool by folate_Homo sapiens_hsa006702.34835733
16Non-homologous end-joining_Homo sapiens_hsa034502.19353104
17Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.16328669
18Basal transcription factors_Homo sapiens_hsa030222.10862210
19Oxidative phosphorylation_Homo sapiens_hsa001902.09805731
20Steroid biosynthesis_Homo sapiens_hsa001002.08580054
21Parkinsons disease_Homo sapiens_hsa050122.07106183
22RNA degradation_Homo sapiens_hsa030182.01517348
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.82842920
24p53 signaling pathway_Homo sapiens_hsa041151.78557666
25mRNA surveillance pathway_Homo sapiens_hsa030151.72650870
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.65519537
27Systemic lupus erythematosus_Homo sapiens_hsa053221.34332267
28Purine metabolism_Homo sapiens_hsa002301.27847431
29Fatty acid elongation_Homo sapiens_hsa000621.26661378
30Herpes simplex infection_Homo sapiens_hsa051681.21854942
31Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.18797196
32Protein export_Homo sapiens_hsa030601.16917610
33Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.11447491
34Propanoate metabolism_Homo sapiens_hsa006401.10496717
35Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.08583466
36Epstein-Barr virus infection_Homo sapiens_hsa051691.08399284
372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.06757237
38Alzheimers disease_Homo sapiens_hsa050101.06411851
39Viral carcinogenesis_Homo sapiens_hsa052030.99775909
40Selenocompound metabolism_Homo sapiens_hsa004500.99329115
41Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.95297962
42Pyruvate metabolism_Homo sapiens_hsa006200.95246617
43Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.92113315
44Antigen processing and presentation_Homo sapiens_hsa046120.91993809
45Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.90416925
46Folate biosynthesis_Homo sapiens_hsa007900.89400560
47HTLV-I infection_Homo sapiens_hsa051660.88554714
48Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.83374810
49Oocyte meiosis_Homo sapiens_hsa041140.81161355
50Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.80825499
51Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.80567212
52Small cell lung cancer_Homo sapiens_hsa052220.79618367
53Transcriptional misregulation in cancer_Homo sapiens_hsa052020.77179414
54Legionellosis_Homo sapiens_hsa051340.75714229
55Thyroid cancer_Homo sapiens_hsa052160.74389233
56MicroRNAs in cancer_Homo sapiens_hsa052060.73002314
57Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.72423756
58Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.71033110
59Notch signaling pathway_Homo sapiens_hsa043300.65446601
60Pentose phosphate pathway_Homo sapiens_hsa000300.65126263
61Measles_Homo sapiens_hsa051620.62711816
62N-Glycan biosynthesis_Homo sapiens_hsa005100.59873090
63Cysteine and methionine metabolism_Homo sapiens_hsa002700.59288920
64Sulfur relay system_Homo sapiens_hsa041220.58832090
65Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.56235490
66Basal cell carcinoma_Homo sapiens_hsa052170.55761577
67Hepatitis B_Homo sapiens_hsa051610.54623194
68Apoptosis_Homo sapiens_hsa042100.54576161
69NF-kappa B signaling pathway_Homo sapiens_hsa040640.53228843
70Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.52606516
71TGF-beta signaling pathway_Homo sapiens_hsa043500.52592955
72Peroxisome_Homo sapiens_hsa041460.51192685
73Colorectal cancer_Homo sapiens_hsa052100.48829019
74Primary immunodeficiency_Homo sapiens_hsa053400.47794501
75Regulation of autophagy_Homo sapiens_hsa041400.47686964
76Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.47461283
77Chronic myeloid leukemia_Homo sapiens_hsa052200.46286450
78Fatty acid metabolism_Homo sapiens_hsa012120.46270945
79Drug metabolism - other enzymes_Homo sapiens_hsa009830.46257655
80Alcoholism_Homo sapiens_hsa050340.45780744
81Biosynthesis of amino acids_Homo sapiens_hsa012300.45389855
82Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.43719779
83Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.43650659
84Hematopoietic cell lineage_Homo sapiens_hsa046400.42178611
85Bladder cancer_Homo sapiens_hsa052190.39749560
86Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.39410640
87Hippo signaling pathway_Homo sapiens_hsa043900.38413141
88Influenza A_Homo sapiens_hsa051640.36685808
89Shigellosis_Homo sapiens_hsa051310.34773954
90Huntingtons disease_Homo sapiens_hsa050160.34357935
91Glutathione metabolism_Homo sapiens_hsa004800.33823283
92RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.32740021
93Pathways in cancer_Homo sapiens_hsa052000.31368519
94Butanoate metabolism_Homo sapiens_hsa006500.30198627
95Prostate cancer_Homo sapiens_hsa052150.29717833
96Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.28551565
97Acute myeloid leukemia_Homo sapiens_hsa052210.28399420
98Pancreatic cancer_Homo sapiens_hsa052120.28258743
99Intestinal immune network for IgA production_Homo sapiens_hsa046720.24611004
100NOD-like receptor signaling pathway_Homo sapiens_hsa046210.23005385
101Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.22935269
102Hedgehog signaling pathway_Homo sapiens_hsa043400.22868691
103Renin-angiotensin system_Homo sapiens_hsa046140.22123122
104Cardiac muscle contraction_Homo sapiens_hsa042600.19794413
105Viral myocarditis_Homo sapiens_hsa054160.19258608
106Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.18583526
107Vitamin B6 metabolism_Homo sapiens_hsa007500.18131154
108Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.17785494
109Jak-STAT signaling pathway_Homo sapiens_hsa046300.17284011
110Central carbon metabolism in cancer_Homo sapiens_hsa052300.17138905
111Lysine degradation_Homo sapiens_hsa003100.16421718
112HIF-1 signaling pathway_Homo sapiens_hsa040660.16403952
113Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.16120197
114Allograft rejection_Homo sapiens_hsa053300.15964961
115Wnt signaling pathway_Homo sapiens_hsa043100.15331186
116Leishmaniasis_Homo sapiens_hsa051400.15240654
117Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.14704357
118Nitrogen metabolism_Homo sapiens_hsa009100.14691662
119Adherens junction_Homo sapiens_hsa045200.14069016
120Non-small cell lung cancer_Homo sapiens_hsa052230.13123374
121Graft-versus-host disease_Homo sapiens_hsa053320.12735631
122PI3K-Akt signaling pathway_Homo sapiens_hsa041510.12432837
123Primary bile acid biosynthesis_Homo sapiens_hsa001200.12200872
124Carbon metabolism_Homo sapiens_hsa012000.11737159
125Metabolic pathways_Homo sapiens_hsa011000.11600203
126Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.11229588
127Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.07384907
128Arginine and proline metabolism_Homo sapiens_hsa003300.07120952
129Phototransduction_Homo sapiens_hsa047440.04955251
130Fatty acid degradation_Homo sapiens_hsa000710.02812207

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