ARMC12

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1spermatid development (GO:0007286)9.96978187
2epithelial cilium movement (GO:0003351)9.65782150
3plasma membrane fusion (GO:0045026)9.63159564
4axonemal dynein complex assembly (GO:0070286)9.58895828
5motile cilium assembly (GO:0044458)9.29025505
6reproduction (GO:0000003)9.16405203
7regulation of cilium movement (GO:0003352)8.76693907
8cilium or flagellum-dependent cell motility (GO:0001539)8.16913625
9cilium movement (GO:0003341)7.77949613
10negative regulation of inclusion body assembly (GO:0090084)7.62342865
11sperm capacitation (GO:0048240)7.27219055
12synaptonemal complex organization (GO:0070193)7.26208873
13single fertilization (GO:0007338)7.20565847
14synaptonemal complex assembly (GO:0007130)7.18581931
15epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.15441250
16male meiosis (GO:0007140)6.97315091
17spermatogenesis (GO:0007283)6.94997709
18male gamete generation (GO:0048232)6.92536653
19piRNA metabolic process (GO:0034587)6.87784196
20organic cation transport (GO:0015695)6.79877408
21microtubule depolymerization (GO:0007019)6.78021824
22short-term memory (GO:0007614)6.49785930
23gamete generation (GO:0007276)6.37285418
24regulation of inclusion body assembly (GO:0090083)6.31995015
25fertilization (GO:0009566)6.19655147
26chromosome condensation (GO:0030261)5.86892824
27calcium ion-dependent exocytosis (GO:0017156)5.64777291
28DNA packaging (GO:0006323)5.53962674
29germ cell development (GO:0007281)5.52028492
30cellular process involved in reproduction in multicellular organism (GO:0022412)5.42188515
31spermatid nucleus differentiation (GO:0007289)5.24878778
32regulation of microtubule-based movement (GO:0060632)5.14524492
33glycerol ether metabolic process (GO:0006662)5.10196387
34multicellular organismal reproductive process (GO:0048609)5.01145282
35microtubule severing (GO:0051013)5.00349875
36cell recognition (GO:0008037)4.99480902
37ventricular system development (GO:0021591)4.95569132
38male meiosis I (GO:0007141)4.86077625
39chromosome organization involved in meiosis (GO:0070192)4.83915650
40regulation of gonadotropin secretion (GO:0032276)4.72162079
41ether metabolic process (GO:0018904)4.71330088
42seminiferous tubule development (GO:0072520)4.71198451
43positive regulation of male gonad development (GO:2000020)4.57947303
44dendritic spine morphogenesis (GO:0060997)4.53855183
45sexual reproduction (GO:0019953)4.51931835
46sex determination (GO:0007530)4.47316115
47DNA methylation involved in gamete generation (GO:0043046)4.43928368
48single strand break repair (GO:0000012)4.39811276
49positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.37038403
50chaperone-mediated protein complex assembly (GO:0051131)4.29045834
51left/right pattern formation (GO:0060972)4.27293915
52protein maturation by protein folding (GO:0022417)4.25095789
53meiotic nuclear division (GO:0007126)4.22758709
54metanephric mesenchyme development (GO:0072075)4.20108440
55skeletal muscle organ development (GO:0060538)4.17114051
56negative regulation of metanephros development (GO:0072217)4.14259345
57regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.14084537
58regulation of male gonad development (GO:2000018)4.13930646
59cardiac muscle hypertrophy in response to stress (GO:0014898)4.07262538
60muscle hypertrophy in response to stress (GO:0003299)4.07262538
61cardiac muscle adaptation (GO:0014887)4.07262538
62cellular response to follicle-stimulating hormone stimulus (GO:0071372)4.03062640
63multicellular organismal development (GO:0007275)4.01869306
64meiosis I (GO:0007127)3.94577479
65deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.94231257
66diaphragm development (GO:0060539)3.92906678
67positive regulation of synapse maturation (GO:0090129)3.91043134
68atrioventricular valve morphogenesis (GO:0003181)3.86080184
69negative regulation of mesenchymal cell apoptotic process (GO:2001054)3.73469150
70sequestering of actin monomers (GO:0042989)3.69025117
71negative regulation of phosphoprotein phosphatase activity (GO:0032515)3.68535562
72behavioral response to nicotine (GO:0035095)3.68532832
73epithelial cell fate commitment (GO:0072148)3.67710400
74cellular response to gonadotropin stimulus (GO:0071371)3.66662325
75male sex determination (GO:0030238)3.66304473
76protein polyglutamylation (GO:0018095)3.62843774
77cell-cell junction maintenance (GO:0045217)3.61841853
78cardiac right ventricle morphogenesis (GO:0003215)3.59693370
79regulation of spindle checkpoint (GO:0090231)3.57786269
80genitalia morphogenesis (GO:0035112)3.55043968
81mesonephros development (GO:0001823)3.48377973
82microtubule polymerization or depolymerization (GO:0031109)3.47442926
83kidney mesenchyme development (GO:0072074)3.47269561
84regulation of female gonad development (GO:2000194)3.45891647
85protein K11-linked deubiquitination (GO:0035871)3.44183537
86regulation of cardioblast differentiation (GO:0051890)3.43174278
87response to parathyroid hormone (GO:0071107)3.43081184
88parturition (GO:0007567)3.41961816
89endocardial cushion development (GO:0003197)3.41557877
90meiotic cell cycle (GO:0051321)3.40531859
91pyrimidine nucleobase catabolic process (GO:0006208)3.38960347
92protein refolding (GO:0042026)3.35817179
93chemosensory behavior (GO:0007635)3.35212894
94camera-type eye morphogenesis (GO:0048593)3.35182781
95positive regulation of mitochondrial fission (GO:0090141)3.34733005
96urinary tract smooth muscle contraction (GO:0014848)3.27877067
97calcium-mediated signaling using intracellular calcium source (GO:0035584)3.27666863
98histone H3-K36 demethylation (GO:0070544)3.25341362
99nucleus organization (GO:0006997)3.24814971
100monoubiquitinated protein deubiquitination (GO:0035520)3.23820941
101cornea development in camera-type eye (GO:0061303)3.22119223
102nonmotile primary cilium assembly (GO:0035058)3.21883445
103interferon-gamma secretion (GO:0072643)3.21050625
104mitotic sister chromatid cohesion (GO:0007064)3.18410136
105glycolytic process (GO:0006096)3.17627262
106positive regulation of filopodium assembly (GO:0051491)3.12419760
107peroxisome fission (GO:0016559)3.10073485
108carnitine transport (GO:0015879)3.08394702
109amino-acid betaine transport (GO:0015838)3.08394702
110establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.07613579
111mitochondrion transport along microtubule (GO:0047497)3.07613579
112polyamine biosynthetic process (GO:0006596)3.05836253
113positive regulation of macrophage activation (GO:0043032)3.04803685
114nucleoside diphosphate phosphorylation (GO:0006165)3.03305625
115positive regulation of sodium ion transmembrane transporter activity (GO:2000651)3.02320288
116establishment of mitochondrion localization (GO:0051654)2.97823242
117polyol catabolic process (GO:0046174)2.97342184
118protein localization to cilium (GO:0061512)2.96108903
119adaptation of signaling pathway (GO:0023058)2.94569690
120epithelial cell differentiation involved in kidney development (GO:0035850)2.93914946
121RNA localization (GO:0006403)2.92999346
122glomerulus development (GO:0032835)2.92080676
123behavioral response to ethanol (GO:0048149)2.91919687
124peptidyl-cysteine modification (GO:0018198)2.91872722
125cardiac muscle hypertrophy (GO:0003300)2.90546943
126carnitine transmembrane transport (GO:1902603)2.89464017
127meiotic cell cycle process (GO:1903046)2.89396952
128RNA destabilization (GO:0050779)2.89198763
129alditol metabolic process (GO:0019400)2.88084674
130positive regulation of receptor biosynthetic process (GO:0010870)2.87503718
131chromatin silencing (GO:0006342)2.86600012
132specification of organ identity (GO:0010092)2.83496937
133cell junction maintenance (GO:0034331)2.82224441
134regulation of cell proliferation involved in kidney development (GO:1901722)2.81631039
135biotin metabolic process (GO:0006768)2.81551033
136positive regulation of dendritic spine development (GO:0060999)2.80458985
137response to redox state (GO:0051775)2.80387648
138peristalsis (GO:0030432)2.79874517
139oxidative demethylation (GO:0070989)2.79735431
140negative regulation of kidney development (GO:0090185)2.79702427
141mitochondrion localization (GO:0051646)2.78330504
142calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.78022297
143sex differentiation (GO:0007548)2.77627134
144GTP biosynthetic process (GO:0006183)2.77430917
145ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.74891610
146regulation of synapse maturation (GO:0090128)2.74075586
147striated muscle hypertrophy (GO:0014897)2.74070032
148synapsis (GO:0007129)2.73494108
149regulation of mesenchymal cell apoptotic process (GO:2001053)2.72639482
150histone H4-K8 acetylation (GO:0043982)2.71391937
151histone H4-K5 acetylation (GO:0043981)2.71391937
152negative regulation of cytosolic calcium ion concentration (GO:0051481)2.70964359
153regulation of cilium assembly (GO:1902017)2.70564196
154metanephric epithelium development (GO:0072207)2.69434717
155mitochondrion degradation (GO:0000422)2.69307089
156positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.67675598
157cilium organization (GO:0044782)2.65978511
158mesenchymal to epithelial transition (GO:0060231)2.65343706
159positive regulation of mesonephros development (GO:0061213)2.65218950
160muscle cell fate commitment (GO:0042693)2.64465186
161positive regulation of amino acid transport (GO:0051957)2.64034647
162positive regulation of action potential (GO:0045760)2.63786335
1634-hydroxyproline metabolic process (GO:0019471)2.63319936
164hindbrain development (GO:0030902)2.63108023
165positive regulation of cellular amine metabolic process (GO:0033240)2.62626083
166microtubule-based movement (GO:0007018)2.61794356
167positive regulation of gastrulation (GO:2000543)2.61764304
168cellular component assembly involved in morphogenesis (GO:0010927)2.55579867
169cilium morphogenesis (GO:0060271)2.55452650
170cilium assembly (GO:0042384)2.54740514
171axoneme assembly (GO:0035082)2.49039709
172UTP biosynthetic process (GO:0006228)2.48113945
173protein localization to chromosome, centromeric region (GO:0071459)2.47819138
174peptidyl-glutamic acid modification (GO:0018200)2.47332201
175negative regulation of organelle assembly (GO:1902116)2.42727625
176intraciliary transport (GO:0042073)2.42295294
177gene silencing by RNA (GO:0031047)2.41697362
178sperm motility (GO:0030317)14.3090060
179cell wall macromolecule catabolic process (GO:0016998)12.9172495
180cell wall macromolecule metabolic process (GO:0044036)12.9172495
181fusion of sperm to egg plasma membrane (GO:0007342)12.6628968
182acrosome reaction (GO:0007340)12.5211658
183acrosome assembly (GO:0001675)11.6191096
184sperm-egg recognition (GO:0035036)11.5931155
185binding of sperm to zona pellucida (GO:0007339)10.6392116
186multicellular organism reproduction (GO:0032504)10.4911188
187cell-cell recognition (GO:0009988)10.3755921

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.28930482
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat5.04492085
3EZH2_22144423_ChIP-Seq_EOC_Human4.13918539
4NR4A2_19515692_ChIP-ChIP_MN9D_Mouse4.02593719
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.99651754
6CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons3.62310026
7RBPJ_22232070_ChIP-Seq_NCS_Mouse3.14173261
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.01075016
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.80828727
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.76640732
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.73921841
12PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.69307922
13VDR_22108803_ChIP-Seq_LS180_Human2.58223066
14ERG_21242973_ChIP-ChIP_JURKAT_Human2.55574683
15IKZF1_21737484_ChIP-ChIP_HCT116_Human2.51010691
16MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.48509915
17CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.34789818
18GATA1_26923725_Chip-Seq_HPCs_Mouse2.33297487
19CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.26060516
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.10979591
21EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.05384725
22HIF1A_21447827_ChIP-Seq_MCF-7_Human2.02434698
23ZNF274_21170338_ChIP-Seq_K562_Hela1.99968148
24CTCF_27219007_Chip-Seq_Bcells_Human1.99811147
25GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.95196745
26FLI1_27457419_Chip-Seq_LIVER_Mouse1.92438929
27CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.91229154
28EZH2_27294783_Chip-Seq_ESCs_Mouse1.86526547
29FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.84853233
30EZH2_27304074_Chip-Seq_ESCs_Mouse1.83911848
31KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.81973290
32ELK4_26923725_Chip-Seq_MESODERM_Mouse1.76786043
33SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.75486799
34STAT1_17558387_ChIP-Seq_HELA_Human1.75182112
35ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.74959012
36GABP_17652178_ChIP-ChIP_JURKAT_Human1.73898153
37SOX2_22085726_ChIP-Seq_NPCs_Mouse1.71640174
38MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.67069259
39TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.65859304
40GATA3_21867929_ChIP-Seq_CD8_Mouse1.64203584
41PCGF2_27294783_Chip-Seq_ESCs_Mouse1.59562082
42ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.59309072
43REST_18959480_ChIP-ChIP_MESCs_Mouse1.57599581
44GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.53018310
45FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.51974580
46DNAJC2_21179169_ChIP-ChIP_NT2_Human1.51624358
47CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.48642028
48CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.48557169
49WDR5_24793694_ChIP-Seq_LNCAP_Human1.47349793
50KAP1_22055183_ChIP-Seq_ESCs_Mouse1.45008542
51ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.44248016
52JARID2_20064375_ChIP-Seq_MESCs_Mouse1.43111757
53PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.42015041
54CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.41408366
55SOX2_18555785_ChIP-Seq_MESCs_Mouse1.41276530
56RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.40308732
57P53_21459846_ChIP-Seq_SAOS-2_Human1.40060141
58OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.39928529
59KDM2B_26808549_Chip-Seq_REH_Human1.39284278
60TP53_20018659_ChIP-ChIP_R1E_Mouse1.36758989
61LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.36494716
62MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.36068913
63TAL1_26923725_Chip-Seq_HPCs_Mouse1.35917887
64SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.35877969
65CBP_20019798_ChIP-Seq_JUKART_Human1.34907914
66IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.34907914
67EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.32012958
68DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.31030073
69GATA3_21867929_ChIP-Seq_TH1_Mouse1.30547809
70ZFP281_18757296_ChIP-ChIP_E14_Mouse1.30256923
71PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.29285044
72RNF2_27304074_Chip-Seq_ESCs_Mouse1.28261539
73REST_21632747_ChIP-Seq_MESCs_Mouse1.27909307
74HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.26482509
75EED_16625203_ChIP-ChIP_MESCs_Mouse1.26409451
76CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26055527
77SA1_27219007_Chip-Seq_ERYTHROID_Human1.25792796
78P68_20966046_ChIP-Seq_HELA_Human1.25337707
79SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24469115
80CREB1_26743006_Chip-Seq_LNCaP_Human1.24200853
81GF1_26923725_Chip-Seq_HPCs_Mouse1.23806185
82RAD21_21589869_ChIP-Seq_MESCs_Mouse1.23398083
83CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.21165884
84SPI1_26923725_Chip-Seq_HPCs_Mouse1.20465783
85FOXP1_21924763_ChIP-Seq_HESCs_Human1.19485168
86ETS1_20019798_ChIP-Seq_JURKAT_Human1.19372239
87CTCF_18555785_ChIP-Seq_MESCs_Mouse1.19229723
88FLI1_21867929_ChIP-Seq_TH2_Mouse1.18593172
89NFE2_27457419_Chip-Seq_LIVER_Mouse1.18422027
90JARID2_20075857_ChIP-Seq_MESCs_Mouse1.17969845
91IRF1_19129219_ChIP-ChIP_H3396_Human1.16276572
92BCL6_27268052_Chip-Seq_Bcells_Human1.16125826
93RARB_24833708_ChIP-Seq_LIVER_Mouse1.16089351
94SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.15543451
95RXRA_24833708_ChIP-Seq_LIVER_Mouse1.15410065
96CBX2_27304074_Chip-Seq_ESCs_Mouse1.15172521
97E2F1_20622854_ChIP-Seq_HELA_Human1.14711366
98SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.14232043
99KDM2B_26808549_Chip-Seq_K562_Human1.14198500
100TET1_21451524_ChIP-Seq_MESCs_Mouse1.13550595
101SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.13199623
102TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13061900
103EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.12732281
104RUNX1_26923725_Chip-Seq_HPCs_Mouse1.12438596
105ERG_20517297_ChIP-Seq_VCAP_Human1.11760804
106SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.11660968
107JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.11582740
108CTBP2_25329375_ChIP-Seq_LNCAP_Human1.11516137
109MYC_27129775_Chip-Seq_CORNEA_Mouse1.11142985
110TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10780930
111POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10780930
112PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.10522212
113EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.09970164
114TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.09571636
115PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09197513
116GATA1_19941827_ChIP-Seq_MEL86_Mouse1.09039730
117RARA_24833708_ChIP-Seq_LIVER_Mouse1.07911326
118YY1_22570637_ChIP-Seq_MALME-3M_Human1.07600895
119ESET_19884257_ChIP-Seq_ESCs_Mouse1.07082501
120JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.06169280
121SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05895999
122RXR_22108803_ChIP-Seq_LS180_Human1.05711211
123RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.05256496
124SUZ12_27294783_Chip-Seq_NPCs_Mouse1.04789429
125PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.04657336
126BMI1_23680149_ChIP-Seq_NPCS_Mouse1.04633869
127ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.04111751
128KDM5A_27292631_Chip-Seq_BREAST_Human1.02972644
129TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02363388
130OCT4_19829295_ChIP-Seq_ESCs_Human1.02182205
131VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.01574508
132CTCF_20526341_ChIP-Seq_ESCs_Human1.01368715
133BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.01199087
134E2F1_17053090_ChIP-ChIP_MCF-7_Human1.00887109
135CRX_20693478_ChIP-Seq_RETINA_Mouse1.00789549
136OCT4_20526341_ChIP-Seq_ESCs_Human1.00269487
137EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.00052881
138LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.99939568
139PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.99487954
140XRN2_22483619_ChIP-Seq_HELA_Human0.98948648
141RING1B_27294783_Chip-Seq_ESCs_Mouse0.98282471
142NFIB_24661679_ChIP-Seq_LUNG_Mouse0.98078417
143SOX11_22085726_ChIP-Seq_ESNs_Mouse0.97509007
144ELK3_25401928_ChIP-Seq_HUVEC_Human0.97177336
145CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.96673445
146BCOR_27268052_Chip-Seq_Bcells_Human0.96670314
147NANOG_18555785_Chip-Seq_ESCs_Mouse0.96317886
148FLI1_21867929_ChIP-Seq_CD8_Mouse0.95905127
149ELF1_20517297_ChIP-Seq_JURKAT_Human0.94815631
150EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.92318320
151GABP_19822575_ChIP-Seq_HepG2_Human0.91660134
152MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.91470176
153SOX3_22085726_ChIP-Seq_NPCs_Mouse0.90967149
154SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.90556733
155DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.90379068
156NFYB_21822215_ChIP-Seq_K562_Human0.90015790
157OCT4_18555785_Chip-Seq_ESCs_Mouse0.90001857
158ELF5_23300383_ChIP-Seq_T47D_Human0.89700023
159RNF2_18974828_ChIP-Seq_MESCs_Mouse0.89481934
160EZH2_18974828_ChIP-Seq_MESCs_Mouse0.89481934
161NANOG_20526341_ChIP-Seq_ESCs_Human0.89414558
162SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.89360403
163RNF2_27304074_Chip-Seq_NSC_Mouse0.89341124
164TAF15_26573619_Chip-Seq_HEK293_Human0.88932442
165ERA_21632823_ChIP-Seq_H3396_Human0.88735302
166RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.88693700
167CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.88628252
168LXR_22292898_ChIP-Seq_THP-1_Human0.88102352
169SMC3_22415368_ChIP-Seq_MEFs_Mouse0.87897590
170CIITA_25753668_ChIP-Seq_RAJI_Human0.87488085
171PHF8_20622854_ChIP-Seq_HELA_Human0.87217211
172CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.87169682
173PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.87150970
174RACK7_27058665_Chip-Seq_MCF-7_Human0.87132287
175SOX2_21211035_ChIP-Seq_LN229_Human0.87007401
176P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.86697836
177RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.86504556
178SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.86350972
179KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.86191206
180P53_22387025_ChIP-Seq_ESCs_Mouse0.86092066
181TAF2_19829295_ChIP-Seq_ESCs_Human0.83660074

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.06967138
2MP0001929_abnormal_gametogenesis5.60728603
3MP0002163_abnormal_gland_morphology4.57983029
4MP0008877_abnormal_DNA_methylation3.95812542
5MP0009384_cardiac_valve_regurgitation3.84979320
6MP0003122_maternal_imprinting3.72317802
7MP0002210_abnormal_sex_determination3.37040531
8MP0002161_abnormal_fertility/fecundity3.34919032
9MP0005379_endocrine/exocrine_gland_phen3.21201087
10MP0005670_abnormal_white_adipose3.04223494
11MP0006292_abnormal_olfactory_placode2.98939220
12MP0001145_abnormal_male_reproductive2.86271588
13MP0000653_abnormal_sex_gland2.48794938
14MP0008789_abnormal_olfactory_epithelium2.41224524
15MP0003121_genomic_imprinting2.38109599
16MP0002822_catalepsy2.33626473
17MP0003315_abnormal_perineum_morphology2.25897970
18MP0002653_abnormal_ependyma_morphology2.16172385
19MP0005394_taste/olfaction_phenotype2.01471753
20MP0005499_abnormal_olfactory_system2.01471753
21MP0005410_abnormal_fertilization16.6506468
22MP0003123_paternal_imprinting1.89954028
23MP0000778_abnormal_nervous_system1.88581658
24MP0000639_abnormal_adrenal_gland1.80458432
25MP0009379_abnormal_foot_pigmentation1.79473701
26MP0003646_muscle_fatigue1.65967149
27MP0001529_abnormal_vocalization1.65553264
28MP0010386_abnormal_urinary_bladder1.64734592
29MP0000537_abnormal_urethra_morphology1.63149619
30MP0000750_abnormal_muscle_regeneration1.62946878
31MP0005645_abnormal_hypothalamus_physiol1.59630943
32MP0003880_abnormal_central_pattern1.48940823
33MP0002160_abnormal_reproductive_system1.48193126
34MP0006276_abnormal_autonomic_nervous1.46801725
35MP0000049_abnormal_middle_ear1.45432970
36MP0002909_abnormal_adrenal_gland1.44757133
37MP0005083_abnormal_biliary_tract1.42701812
38MP0004885_abnormal_endolymph1.41483786
39MP0004233_abnormal_muscle_weight1.40877030
40MP0003567_abnormal_fetal_cardiomyocyte1.40696165
41MP0005423_abnormal_somatic_nervous1.35059301
42MP0001919_abnormal_reproductive_system1.33463162
43MP0002277_abnormal_respiratory_mucosa1.33165742
44MP0001346_abnormal_lacrimal_gland1.31861970
45MP0002233_abnormal_nose_morphology1.30644613
46MP0002735_abnormal_chemical_nociception1.30601653
47MP0003136_yellow_coat_color1.29171892
48MP0002876_abnormal_thyroid_physiology1.29029909
49MP0004859_abnormal_synaptic_plasticity1.24200683
50MP0000955_abnormal_spinal_cord1.21607204
51MP0005623_abnormal_meninges_morphology1.20548588
52MP0005248_abnormal_Harderian_gland1.17758482
53MP0000566_synostosis1.16336794
54MP0001502_abnormal_circadian_rhythm1.16137097
55MP0003755_abnormal_palate_morphology1.12549065
56MP0002272_abnormal_nervous_system1.10918090
57MP0001765_abnormal_ion_homeostasis1.10384445
58MP0002282_abnormal_trachea_morphology1.09572686
59MP0002127_abnormal_cardiovascular_syste1.08787717
60MP0001970_abnormal_pain_threshold1.03818023
61MP0003938_abnormal_ear_development1.03082397
62MP0002733_abnormal_thermal_nociception1.01188699
63MP0002249_abnormal_larynx_morphology1.00713219
64MP0002557_abnormal_social/conspecific_i0.99537964
65MP0001485_abnormal_pinna_reflex0.98247051
66MP0001984_abnormal_olfaction0.95609866
67MP0002234_abnormal_pharynx_morphology0.93670785
68MP0004142_abnormal_muscle_tone0.93252765
69MP0008058_abnormal_DNA_repair0.92434249
70MP0003045_fibrosis0.89265853
71MP0002837_dystrophic_cardiac_calcinosis0.87836470
72MP0005647_abnormal_sex_gland0.85655269
73MP0003936_abnormal_reproductive_system0.85251163
74MP0009745_abnormal_behavioral_response0.80466481
75MP0002063_abnormal_learning/memory/cond0.79906632
76MP0002882_abnormal_neuron_morphology0.78491758
77MP0005310_abnormal_salivary_gland0.76546906
78MP0001905_abnormal_dopamine_level0.76167261
79MP0005389_reproductive_system_phenotype0.75797405
80MP0002638_abnormal_pupillary_reflex0.74509632
81MP0002572_abnormal_emotion/affect_behav0.72999048
82MP0002693_abnormal_pancreas_physiology0.72605854
83MP0000026_abnormal_inner_ear0.71235211
84MP0003115_abnormal_respiratory_system0.70049863
85MP0008995_early_reproductive_senescence0.69761974
86MP0009046_muscle_twitch0.69506796
87MP0001486_abnormal_startle_reflex0.69470104
88MP0000631_abnormal_neuroendocrine_gland0.69055889
89MP0003635_abnormal_synaptic_transmissio0.68904964
90MP0002752_abnormal_somatic_nervous0.67906090
91MP0005377_hearing/vestibular/ear_phenot0.65287376
92MP0003878_abnormal_ear_physiology0.65287376
93MP0005636_abnormal_mineral_homeostasis0.64923586
94MP0003011_delayed_dark_adaptation0.64519819
95MP0005666_abnormal_adipose_tissue0.61421116
96MP0010094_abnormal_chromosome_stability0.58802287
97MP0003329_amyloid_beta_deposits0.55016717
98MP0001764_abnormal_homeostasis0.53442906
99MP0003699_abnormal_female_reproductive0.53298529
100MP0004036_abnormal_muscle_relaxation0.52791341
101MP0003111_abnormal_nucleus_morphology0.51752461
102MP0005397_hematopoietic_system_phenotyp0.49768005
103MP0001545_abnormal_hematopoietic_system0.49768005
104MP0000358_abnormal_cell_content/0.48197525
105MP0001293_anophthalmia0.47912274
106MP0002736_abnormal_nociception_after0.47053142
107MP0002269_muscular_atrophy0.46026572
108MP0009278_abnormal_bone_marrow0.45131762
109MP0001324_abnormal_eye_pigmentation0.44693345
110MP0006036_abnormal_mitochondrial_physio0.43001388
111MP0000569_abnormal_digit_pigmentation0.42913405
112MP0000534_abnormal_ureter_morphology0.39195812
113MP0001730_embryonic_growth_arrest0.37192821
114MP0009115_abnormal_fat_cell0.36228977
115MP0005253_abnormal_eye_physiology0.34952135
116MP0001119_abnormal_female_reproductive0.32747789
117MP0002928_abnormal_bile_duct0.32228384
118MP0004133_heterotaxia0.31852962
119MP0005551_abnormal_eye_electrophysiolog0.29616117
120MP0003950_abnormal_plasma_membrane0.28922316
121MP0005391_vision/eye_phenotype0.28696165
122MP0003879_abnormal_hair_cell0.28047864
123MP0000604_amyloidosis0.27097146
124MP0003942_abnormal_urinary_system0.26193055
125MP0002102_abnormal_ear_morphology0.25750338
126MP0003786_premature_aging0.25706892
127MP0002971_abnormal_brown_adipose0.25686310
128MP0004019_abnormal_vitamin_homeostasis0.25534193
129MP0002169_no_abnormal_phenotype0.25397547
130MP0002873_normal_phenotype0.25138838
131MP0004811_abnormal_neuron_physiology0.25057913
132MP0003861_abnormal_nervous_system0.23769663
133MP0002139_abnormal_hepatobiliary_system0.23762244
134MP0008007_abnormal_cellular_replicative0.23354393
135MP0003633_abnormal_nervous_system0.21901730
136MP0001968_abnormal_touch/_nociception0.21793806
137MP0010307_abnormal_tumor_latency0.20660866
138MP0004742_abnormal_vestibular_system0.20355009
139MP0003948_abnormal_gas_homeostasis0.20218597
140MP0006035_abnormal_mitochondrial_morpho0.20214549
141MP0008057_abnormal_DNA_replication0.20152204
142MP0001849_ear_inflammation0.19633207
143MP0002152_abnormal_brain_morphology0.19011085
144MP0003077_abnormal_cell_cycle0.18538702
145MP0003631_nervous_system_phenotype0.18338937
146MP0001727_abnormal_embryo_implantation0.18336425
147MP0000313_abnormal_cell_death0.17676512
148MP0001672_abnormal_embryogenesis/_devel0.17655982
149MP0005380_embryogenesis_phenotype0.17655982
150MP0008875_abnormal_xenobiotic_pharmacok0.17654308
151MP0001661_extended_life_span0.17624531
152MP0002295_abnormal_pulmonary_circulatio0.17336544
153MP0002092_abnormal_eye_morphology0.17258000
154MP0004808_abnormal_hematopoietic_stem0.17060970
155MP0005375_adipose_tissue_phenotype0.16962512
156MP0002084_abnormal_developmental_patter0.16118249
157MP0000001_mammalian_phenotype0.16046985
158MP0004145_abnormal_muscle_electrophysio0.15586055
159MP0003787_abnormal_imprinting0.15508898
160MP0001697_abnormal_embryo_size0.15377217
161MP0004043_abnormal_pH_regulation0.15159654
162MP0002405_respiratory_system_inflammati0.13538881
163MP0000462_abnormal_digestive_system0.12826676
164MP0005319_abnormal_enzyme/_coenzyme0.12447439
165MP0002132_abnormal_respiratory_system0.12270844
166MP0008961_abnormal_basal_metabolism0.12116572

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.33506981
2Abnormal respiratory motile cilium morphology (HP:0005938)9.19127970
3Abnormal respiratory epithelium morphology (HP:0012253)9.19127970
4Rhinitis (HP:0012384)7.48003113
5Chronic bronchitis (HP:0004469)7.47669868
6Infertility (HP:0000789)7.27533837
7Abnormal ciliary motility (HP:0012262)7.22813495
8Gonadal dysgenesis (HP:0000133)6.54160480
9Nasal polyposis (HP:0100582)6.44649150
10Testicular neoplasm (HP:0010788)5.62795799
11Sex reversal (HP:0012245)5.45490364
12Abnormal sex determination (HP:0012244)5.45490364
13Abnormality of the nasal mucosa (HP:0000433)5.29592596
14Male infertility (HP:0003251)5.23586895
15Bronchitis (HP:0012387)4.65848946
16Hypoplastic left heart (HP:0004383)4.60192192
17Anomalous pulmonary venous return (HP:0010772)4.45693685
18Bronchiectasis (HP:0002110)4.43321007
19Mesangial abnormality (HP:0001966)4.13175031
20Nephronophthisis (HP:0000090)4.03938576
21Abnormal spermatogenesis (HP:0008669)3.86747569
22Abnormality of the pulmonary veins (HP:0011718)3.75815490
23Intestinal atresia (HP:0011100)3.74499068
24Chronic hepatic failure (HP:0100626)3.72860738
25Germ cell neoplasia (HP:0100728)3.66764004
26Hypoplastic heart (HP:0001961)3.62107071
27Oligodactyly (hands) (HP:0001180)3.50077442
28Retinal dysplasia (HP:0007973)3.34464803
29Recurrent otitis media (HP:0000403)3.33496894
30Male pseudohermaphroditism (HP:0000037)3.30429100
31Oligodactyly (HP:0012165)3.28825905
32True hermaphroditism (HP:0010459)3.26711937
33Recurrent sinusitis (HP:0011108)3.22276117
34Polyphagia (HP:0002591)3.22166476
35Abnormality of the vocal cords (HP:0008777)3.22094407
36Progressive inability to walk (HP:0002505)3.11533139
37Transposition of the great arteries (HP:0001669)3.10323911
38Abnormal connection of the cardiac segments (HP:0011545)3.10323911
39Abnormal ventriculo-arterial connection (HP:0011563)3.10323911
40Abnormality of the renal medulla (HP:0100957)3.01890231
41Failure to thrive in infancy (HP:0001531)2.93253839
42Impulsivity (HP:0100710)2.93008454
43Recurrent bronchitis (HP:0002837)2.77968332
44Tubulointerstitial nephritis (HP:0001970)2.64671457
45Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.64349399
46Decreased activity of mitochondrial respiratory chain (HP:0008972)2.64349399
47Sleep apnea (HP:0010535)2.58632507
48Molar tooth sign on MRI (HP:0002419)2.54328950
49Abnormality of midbrain morphology (HP:0002418)2.54328950
50Tubular atrophy (HP:0000092)2.54123929
51Abnormal gallbladder physiology (HP:0012438)2.49328572
52Cholecystitis (HP:0001082)2.49328572
53Abnormal lung lobation (HP:0002101)2.39864235
54Azoospermia (HP:0000027)2.38782304
55Hyperthyroidism (HP:0000836)2.38113042
56Beaking of vertebral bodies (HP:0004568)2.36593534
57Tubulointerstitial abnormality (HP:0001969)2.35689862
58Hand muscle atrophy (HP:0009130)2.32946266
59Gonadotropin excess (HP:0000837)2.32785337
60Primary adrenal insufficiency (HP:0008207)2.32160849
61Myokymia (HP:0002411)2.31308879
62Medial flaring of the eyebrow (HP:0010747)2.22900288
63Broad alveolar ridges (HP:0000187)2.20249474
64Dyschromatopsia (HP:0007641)2.19245725
65Rhabdomyosarcoma (HP:0002859)2.18603903
66Female pseudohermaphroditism (HP:0010458)2.18084800
67Hypokinesia (HP:0002375)2.08431555
68Aplasia/Hypoplasia of the sacrum (HP:0008517)2.05436861
69J-shaped sella turcica (HP:0002680)2.05419336
70Choroideremia (HP:0001139)2.02731960
71Flattened epiphyses (HP:0003071)2.02538046
72Papilledema (HP:0001085)2.02324652
73Ileus (HP:0002595)2.01601613
74Rimmed vacuoles (HP:0003805)2.01253918
75Hyperglycinemia (HP:0002154)2.00694445
76Absent/shortened dynein arms (HP:0200106)13.3673118
77Dynein arm defect of respiratory motile cilia (HP:0012255)13.3673118
78Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.0998760
79Agitation (HP:0000713)1.98990375
80Spastic tetraparesis (HP:0001285)1.97843664
81Tubulointerstitial fibrosis (HP:0005576)1.97414791
82Insomnia (HP:0100785)1.97074682
83Ragged-red muscle fibers (HP:0003200)1.96106721
84Hip dysplasia (HP:0001385)1.95990078
85Hypsarrhythmia (HP:0002521)1.95356380
86Decreased central vision (HP:0007663)1.95173359
87High anterior hairline (HP:0009890)1.93553061
88Adrenal hypoplasia (HP:0000835)1.92219832
89Rib fusion (HP:0000902)1.90152312
90Congenital malformation of the right heart (HP:0011723)1.88588301
91Double outlet right ventricle (HP:0001719)1.88588301
92Drooling (HP:0002307)1.88115194
93Hypoplasia of the uterus (HP:0000013)1.87361352
94Intellectual disability, moderate (HP:0002342)1.86537941
9511 pairs of ribs (HP:0000878)1.86391903
96Biconcave vertebral bodies (HP:0004586)1.85775092
97Nephroblastoma (Wilms tumor) (HP:0002667)1.85658388
98EEG with generalized epileptiform discharges (HP:0011198)1.85508352
99Epileptiform EEG discharges (HP:0011182)1.84335084
100Facial diplegia (HP:0001349)1.83519251
101Flat capital femoral epiphysis (HP:0003370)1.83356598
102Esotropia (HP:0000565)1.82962677
103Gastrointestinal atresia (HP:0002589)1.82212318
104Abnormal drinking behavior (HP:0030082)1.80733797
105Polydipsia (HP:0001959)1.80733797
106Hemorrhage of the eye (HP:0011885)1.76191953
107Congenital diaphragmatic hernia (HP:0000776)1.76190204
108Excessive salivation (HP:0003781)1.75726743
109Delayed gross motor development (HP:0002194)1.75626125
110Aplasia/hypoplasia of the uterus (HP:0008684)1.75513132
111Hypoplasia of the capital femoral epiphysis (HP:0003090)1.73503652
112Postaxial foot polydactyly (HP:0001830)1.73054069
113Short nail (HP:0001799)1.72730309
114Optic nerve coloboma (HP:0000588)1.68264230
115Stage 5 chronic kidney disease (HP:0003774)1.68073787
116Bile duct proliferation (HP:0001408)1.67741088
117Abnormal biliary tract physiology (HP:0012439)1.67741088
118Heterotopia (HP:0002282)1.67488213
119Abnormality of the corticospinal tract (HP:0002492)1.66903325
120Abnormality of the labia minora (HP:0012880)1.66337954
121Abnormality of renal excretion (HP:0011036)1.65467292
122Facial hemangioma (HP:0000329)1.65465436
123Bradykinesia (HP:0002067)1.65053259
124Atelectasis (HP:0100750)1.63946516
125Neurofibrillary tangles (HP:0002185)1.62137173
126Congenital hepatic fibrosis (HP:0002612)1.61712239
127Embryonal renal neoplasm (HP:0011794)1.61431517
128Renal salt wasting (HP:0000127)1.60599012
129Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.60246226
130Degeneration of the lateral corticospinal tracts (HP:0002314)1.60246226
131Neoplasm of striated muscle (HP:0009728)1.60117649
132Decreased electroretinogram (ERG) amplitude (HP:0000654)1.59718881
133Abnormality of the renal cortex (HP:0011035)1.53347076
134Short ribs (HP:0000773)1.52889938
135Oculomotor apraxia (HP:0000657)1.49341094
136Bundle branch block (HP:0011710)1.48994921
137Bell-shaped thorax (HP:0001591)1.48545129
138Asymmetric septal hypertrophy (HP:0001670)1.47256693
139Aplasia/Hypoplasia of the lens (HP:0008063)1.43236770
140Facial cleft (HP:0002006)1.42130514
141Abnormality of permanent molar morphology (HP:0011071)1.41772194
142Abnormality of the dental root (HP:0006486)1.41772194
143Taurodontia (HP:0000679)1.41772194
144Abnormal urine output (HP:0012590)1.41765686
145Easy fatigability (HP:0003388)1.41192330
146Exercise-induced myalgia (HP:0003738)1.39270195
147Renal dysplasia (HP:0000110)1.38969948
148Fibular hypoplasia (HP:0003038)1.38567052
149Absent epiphyses (HP:0010577)1.35664873
150Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.35664873
151Postaxial hand polydactyly (HP:0001162)1.34088978
152Deformed sella turcica (HP:0002681)1.33716785
153Abnormality of dentin (HP:0010299)1.32871589
154Abnormality of the dental pulp (HP:0006479)1.32222320
155Cystic liver disease (HP:0006706)1.32002225
156Abnormality of the lower motor neuron (HP:0002366)1.31088630
157Constricted visual fields (HP:0001133)1.30149227
158Cerebral inclusion bodies (HP:0100314)1.29868293
159Abnormality of molar (HP:0011077)1.29773766
160Abnormality of molar morphology (HP:0011070)1.29773766
161Fatigable weakness (HP:0003473)1.28506390
162Abnormality of the neuromuscular junction (HP:0003398)1.28506390
163Myoglobinuria (HP:0002913)1.26279272
164Pancreatic fibrosis (HP:0100732)1.25454766
165Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.24217503
166Broad distal phalanx of finger (HP:0009836)1.23464292
167Hypercholesterolemia (HP:0003124)1.23214089
168Sensory axonal neuropathy (HP:0003390)1.20423280
169Amyotrophic lateral sclerosis (HP:0007354)1.20191309
170Rhabdomyolysis (HP:0003201)1.19348103
171Loss of speech (HP:0002371)1.19317080
172Hemiparesis (HP:0001269)1.19086306
173Chronic sinusitis (HP:0011109)1.18013842
174Polyuria (HP:0000103)1.17568268
175Short femoral neck (HP:0100864)1.16871948
176Cerebellar dysplasia (HP:0007033)1.16557989
177Nephropathy (HP:0000112)1.14853466
178Truncal obesity (HP:0001956)1.14003296
179Personality changes (HP:0000751)1.12621286
180Short thorax (HP:0010306)1.10767098

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.94417893
2PDK47.94417893
3TESK16.60354868
4PRKD35.26867759
5PDK25.12715658
6ICK4.65993087
7CDK192.94848127
8EPHB12.82302701
9EPHB22.59776439
10PAK32.44532965
11DYRK22.33862153
12PTK2B2.22758130
13SGK2232.21196264
14SGK4942.21196264
15TRIM282.18763730
16PRPF4B2.15450174
17WNK42.13110249
18STK392.04477995
19STK381.97074105
20PNCK1.81264415
21NEK21.75912402
22DYRK1B1.67068527
23PKN21.65594552
24PRKCI1.60550527
25MINK11.60335627
26TAOK21.59418630
27CDK81.58286868
28MAP2K71.55558920
29PHKG21.54579996
30PHKG11.54579996
31CASK1.49552544
32NLK1.44976871
33MARK11.44608292
34EPHA31.36124792
35PDK11.27407727
36TNK21.25972822
37FER1.23406928
38SIK31.21822421
39TRIB31.16603422
40YES11.16302956
41LRRK21.12548730
42SRPK11.08013891
43CAMK1D1.01677344
44DYRK31.01531422
45EPHA21.01394456
46SGK21.00158184
47DYRK1A0.87626254
48TYRO30.86045113
49RIPK40.85434963
50PDPK10.84869550
51SIK10.84650957
52PTK60.82972520
53RPS6KA20.82805942
54UHMK10.81522413
55MAPK150.79515947
56CCNB10.76730180
57SGK30.76512642
58BCR0.76064475
59WNK10.75278987
60MAP3K40.73777970
61EEF2K0.72536491
62IRAK10.72385765
63TTK0.71580584
64CAMK10.71028517
65SIK20.71020005
66ARAF0.69331385
67STK30.69092854
68MAP3K70.67415686
69TESK20.67021580
70EPHA40.66280023
71PINK10.66162416
72PASK0.65795514
73PTK20.64636597
74CHEK20.62902818
75MAP4K20.62115000
76MAP2K40.60315773
77MAP2K30.60313887
78STK38L0.58215300
79MUSK0.52618879
80MAP2K60.52256630
81PRKD20.52071365
82FGFR10.51920270
83RPS6KC10.49014798
84RPS6KL10.49014798
85RPS6KA60.45719405
86WEE10.45605975
87NTRK20.45172428
88MAP3K10.44333478
89PAK10.44066980
90ERN10.43164833
91BRD40.42995300
92BCKDK0.42104355
93NTRK10.41647343
94MAPK130.41379419
95CAMK1G0.41244664
96DDR20.40913063
97CHEK10.40662736
98IRAK20.39606720
99PRKCG0.39164513
100MAP3K110.38776465
101BMPR1B0.38077573
102LMTK20.36057724
103CSNK1A10.35183346
104BRSK20.34079939
105AKT20.33732621
106MAPK90.33360764
107SGK10.33144608
108ALK0.31172936
109TNIK0.30780055
110FLT30.30186036
111MAP3K100.30081835
112HIPK20.29702202
113CDK50.28945019
114MAPKAPK50.28105262
115PAK20.26639796
116ATM0.26379175
117PLK40.25360020
118PAK40.24755679
119ATR0.24285663
120MTOR0.23740811
121CAMKK10.23711572
122MARK20.23453582
123BRSK10.22330332
124PRKAA10.21463785
125PLK10.20714390
126BRAF0.19316703
127PRKCZ0.19234795
128CDC70.18415187
129CDK150.17395916
130NEK60.15615193
131PRKCQ0.14828672
132STK100.14645220
133CDK180.14381865
134CDK11A0.13462453
135BUB10.13268480
136RPS6KB10.12556410
137MARK30.10348346
138RPS6KA10.09430476
139CSNK2A10.09002106
140PRKG20.08752999
141CDK140.08611867
142PIM10.08522063
143ZAP700.06835413
144GSK3B0.06608267
145CDK60.06194173
146AURKA0.05374483
147STK110.04757240
148CDK20.04749439
149CSF1R0.04400400
150CDK10.03969608
151PRKCD0.03425867
152CDK40.03066498
153CSNK2A20.02075651
154MAPK80.01879731
155CLK10.01411827
156PRKACG0.01254295
157PRKG10.01004355
158CAMK2A0.00542259
159MAP3K50.00528249
160PDGFRB-0.0434475
161TAOK1-0.0399339
162PRKACB-0.0385720
163EGFR-0.0378515
164RPS6KA3-0.0367360
165PKN1-0.0336543
166CDK3-0.0312310
167WNK3-0.0126452
168CSNK1D-0.0117140
169PAK6-0.0056792
170PRKCA-0.0002988
171PRKCB-0.0001864

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.78184222
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.44896592
3Vitamin B6 metabolism_Homo sapiens_hsa007503.89631872
4alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.30320948
5Pyruvate metabolism_Homo sapiens_hsa006203.22890275
6Linoleic acid metabolism_Homo sapiens_hsa005913.22587529
7Steroid biosynthesis_Homo sapiens_hsa001002.84197509
8Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.74295356
9Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.72442854
10Glucagon signaling pathway_Homo sapiens_hsa049222.53650695
11Propanoate metabolism_Homo sapiens_hsa006402.41528150
12Basal transcription factors_Homo sapiens_hsa030222.40397075
13Carbohydrate digestion and absorption_Homo sapiens_hsa049732.38663782
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.25429080
15Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.22905222
16Axon guidance_Homo sapiens_hsa043602.07014842
17Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005342.06168156
18Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.04129999
19Arginine and proline metabolism_Homo sapiens_hsa003302.00030073
20Ribosome_Homo sapiens_hsa030101.99715718
21Glycerolipid metabolism_Homo sapiens_hsa005611.97112490
22Butanoate metabolism_Homo sapiens_hsa006501.94691548
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.93264175
24Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.92252231
25Selenocompound metabolism_Homo sapiens_hsa004501.91590164
26Glycerophospholipid metabolism_Homo sapiens_hsa005641.89449706
27PPAR signaling pathway_Homo sapiens_hsa033201.82537810
28beta-Alanine metabolism_Homo sapiens_hsa004101.81345966
29Fatty acid elongation_Homo sapiens_hsa000621.73542534
30Basal cell carcinoma_Homo sapiens_hsa052171.73027179
31Primary bile acid biosynthesis_Homo sapiens_hsa001201.72349142
32Phenylalanine metabolism_Homo sapiens_hsa003601.70780119
33Pentose phosphate pathway_Homo sapiens_hsa000301.70674170
34Oocyte meiosis_Homo sapiens_hsa041141.68828717
35Histidine metabolism_Homo sapiens_hsa003401.67687159
36Fructose and mannose metabolism_Homo sapiens_hsa000511.65132365
37Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.64164242
38Peroxisome_Homo sapiens_hsa041461.59690347
39Mineral absorption_Homo sapiens_hsa049781.57217005
40Fat digestion and absorption_Homo sapiens_hsa049751.55944921
41Tyrosine metabolism_Homo sapiens_hsa003501.55539447
42Sulfur relay system_Homo sapiens_hsa041221.53183413
43Ether lipid metabolism_Homo sapiens_hsa005651.52226182
44Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.47447639
45Amphetamine addiction_Homo sapiens_hsa050311.47180457
46Lysine degradation_Homo sapiens_hsa003101.41333185
47Dorso-ventral axis formation_Homo sapiens_hsa043201.40553929
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.39611576
49Drug metabolism - other enzymes_Homo sapiens_hsa009831.39187417
50Fatty acid metabolism_Homo sapiens_hsa012121.38417176
51Fatty acid degradation_Homo sapiens_hsa000711.38241383
52Carbon metabolism_Homo sapiens_hsa012001.35264433
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.33310049
54Glycosaminoglycan degradation_Homo sapiens_hsa005311.29733596
55RNA polymerase_Homo sapiens_hsa030201.27697019
56Cyanoamino acid metabolism_Homo sapiens_hsa004601.24337140
57Cardiac muscle contraction_Homo sapiens_hsa042601.23073646
58Fanconi anemia pathway_Homo sapiens_hsa034601.21645193
59Parkinsons disease_Homo sapiens_hsa050121.18415917
60Cysteine and methionine metabolism_Homo sapiens_hsa002701.17948743
61Oxidative phosphorylation_Homo sapiens_hsa001901.17311060
62Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.15593999
63Purine metabolism_Homo sapiens_hsa002301.12856805
64Caffeine metabolism_Homo sapiens_hsa002321.10089764
65Antigen processing and presentation_Homo sapiens_hsa046121.09026038
66Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.05896668
67Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.00483315
68Glutathione metabolism_Homo sapiens_hsa004801.00166083
69Collecting duct acid secretion_Homo sapiens_hsa049660.99214607
70Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.98487527
71Hedgehog signaling pathway_Homo sapiens_hsa043400.97596842
72Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.96898039
73RNA transport_Homo sapiens_hsa030130.96620296
74mRNA surveillance pathway_Homo sapiens_hsa030150.96370037
75Renin secretion_Homo sapiens_hsa049240.95280741
76Hippo signaling pathway_Homo sapiens_hsa043900.94372895
77Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.93391404
78Biosynthesis of amino acids_Homo sapiens_hsa012300.92277159
79Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.90735984
80Arachidonic acid metabolism_Homo sapiens_hsa005900.89704949
81Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.85001940
82Huntingtons disease_Homo sapiens_hsa050160.84727859
83Adipocytokine signaling pathway_Homo sapiens_hsa049200.83540527
84Steroid hormone biosynthesis_Homo sapiens_hsa001400.80495163
85Notch signaling pathway_Homo sapiens_hsa043300.79921799
86Chemical carcinogenesis_Homo sapiens_hsa052040.77223271
87Insulin secretion_Homo sapiens_hsa049110.76063677
88Phototransduction_Homo sapiens_hsa047440.75966298
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.74905275
90Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.74846936
91Estrogen signaling pathway_Homo sapiens_hsa049150.70889660
92Long-term potentiation_Homo sapiens_hsa047200.69865797
93Thyroid hormone synthesis_Homo sapiens_hsa049180.69422671
94Bile secretion_Homo sapiens_hsa049760.67073309
95Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.65930173
96cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64749688
97Vibrio cholerae infection_Homo sapiens_hsa051100.62929151
98Legionellosis_Homo sapiens_hsa051340.60960035
99Protein export_Homo sapiens_hsa030600.59548832
100Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.58530643
101Alzheimers disease_Homo sapiens_hsa050100.58225360
102Renin-angiotensin system_Homo sapiens_hsa046140.57539220
103ErbB signaling pathway_Homo sapiens_hsa040120.55434468
104Central carbon metabolism in cancer_Homo sapiens_hsa052300.54275142
105Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54109701
106Dopaminergic synapse_Homo sapiens_hsa047280.53582581
107Aldosterone synthesis and secretion_Homo sapiens_hsa049250.53522038
108N-Glycan biosynthesis_Homo sapiens_hsa005100.52570551
109Pancreatic secretion_Homo sapiens_hsa049720.52022029
110Pyrimidine metabolism_Homo sapiens_hsa002400.51785028
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.51625822
112Tight junction_Homo sapiens_hsa045300.51249320
113Systemic lupus erythematosus_Homo sapiens_hsa053220.50382197
114Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.47041895
115Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.46881359
116Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.46380149
117Vascular smooth muscle contraction_Homo sapiens_hsa042700.45925064
118Salivary secretion_Homo sapiens_hsa049700.44792490
119Endocytosis_Homo sapiens_hsa041440.44083661
120Nicotine addiction_Homo sapiens_hsa050330.43915123
121AMPK signaling pathway_Homo sapiens_hsa041520.43257622
122Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.42992030
1232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.41577335
124Synaptic vesicle cycle_Homo sapiens_hsa047210.41518489
125Protein digestion and absorption_Homo sapiens_hsa049740.41387003
126Retinol metabolism_Homo sapiens_hsa008300.40798599
127Calcium signaling pathway_Homo sapiens_hsa040200.40524357
128ABC transporters_Homo sapiens_hsa020100.39920106
129Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.39570367
130MAPK signaling pathway_Homo sapiens_hsa040100.38956963
131Thyroid hormone signaling pathway_Homo sapiens_hsa049190.38765402
132Base excision repair_Homo sapiens_hsa034100.38461355
133Metabolic pathways_Homo sapiens_hsa011000.37526552
134GABAergic synapse_Homo sapiens_hsa047270.37399482
135Galactose metabolism_Homo sapiens_hsa000520.36949694
136Morphine addiction_Homo sapiens_hsa050320.36878623
137Inositol phosphate metabolism_Homo sapiens_hsa005620.35949699
138VEGF signaling pathway_Homo sapiens_hsa043700.35881011
139Gastric acid secretion_Homo sapiens_hsa049710.32435288
140Phosphatidylinositol signaling system_Homo sapiens_hsa040700.31936326
141Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.29178404
142Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.28884881
143Pentose and glucuronate interconversions_Homo sapiens_hsa000400.28181090
144Sulfur metabolism_Homo sapiens_hsa009200.26458276
145cAMP signaling pathway_Homo sapiens_hsa040240.25913869
146Alcoholism_Homo sapiens_hsa050340.22821447
147Taste transduction_Homo sapiens_hsa047420.19193447
148Cocaine addiction_Homo sapiens_hsa050300.17618362
149Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.13000052
150HIF-1 signaling pathway_Homo sapiens_hsa040660.12199200
151Cell cycle_Homo sapiens_hsa041100.11568075
152Circadian entrainment_Homo sapiens_hsa047130.11144710
153B cell receptor signaling pathway_Homo sapiens_hsa046620.10459171
154Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.09791914
155Salmonella infection_Homo sapiens_hsa051320.08773159
156Wnt signaling pathway_Homo sapiens_hsa043100.08095831
157RNA degradation_Homo sapiens_hsa030180.07610589
158Epstein-Barr virus infection_Homo sapiens_hsa051690.05751555

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