ARMC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of DNA methylation (GO:0044030)8.66835253
2regulation of meiosis I (GO:0060631)8.13869418
3regulation of female gonad development (GO:2000194)7.13556335
4cilium or flagellum-dependent cell motility (GO:0001539)6.86262651
5meiotic cell cycle (GO:0051321)6.85812690
6retinal cone cell development (GO:0046549)6.76328667
7centriole replication (GO:0007099)6.22760545
8axonemal dynein complex assembly (GO:0070286)6.18973375
9cilium movement (GO:0003341)5.71378640
10motile cilium assembly (GO:0044458)5.68747568
11female gamete generation (GO:0007292)5.59551322
12polyketide metabolic process (GO:0030638)5.47927468
13doxorubicin metabolic process (GO:0044598)5.47927468
14daunorubicin metabolic process (GO:0044597)5.47927468
15epithelial cilium movement (GO:0003351)5.39300105
16regulation of cell maturation (GO:1903429)4.97430662
17epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.90933044
18synapsis (GO:0007129)4.76764258
19glycine transport (GO:0015816)4.63973221
20positive regulation of gastrulation (GO:2000543)4.57676605
21multicellular organism reproduction (GO:0032504)4.53131226
22gene silencing by RNA (GO:0031047)4.45066997
23regulation of steroid hormone secretion (GO:2000831)4.41908216
24regulation of histone H3-K9 methylation (GO:0051570)4.40805024
25acrosome reaction (GO:0007340)4.40792153
26pyrimidine-containing compound transmembrane transport (GO:0072531)4.40650852
27relaxation of smooth muscle (GO:0044557)4.39132101
28oocyte development (GO:0048599)4.30037487
29neuron fate determination (GO:0048664)4.16732480
30positive regulation of histone H3-K4 methylation (GO:0051571)4.14646755
31sperm motility (GO:0030317)4.13080671
32positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.12440672
33positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.12440672
34positive regulation of mitotic sister chromatid separation (GO:1901970)4.12440672
35regulation of acrosome reaction (GO:0060046)4.10200806
36fusion of sperm to egg plasma membrane (GO:0007342)4.06440636
37axoneme assembly (GO:0035082)4.04366403
38male meiosis I (GO:0007141)4.01613680
39protein localization to cilium (GO:0061512)3.94356061
40acrosome assembly (GO:0001675)3.92972623
41synaptonemal complex assembly (GO:0007130)3.92582051
42cell wall macromolecule metabolic process (GO:0044036)3.87058093
43cell wall macromolecule catabolic process (GO:0016998)3.87058093
44regulation of cilium movement (GO:0003352)3.81260222
45chromosome organization involved in meiosis (GO:0070192)3.80086057
46auditory receptor cell stereocilium organization (GO:0060088)3.74659087
47primitive streak formation (GO:0090009)3.71783147
48response to pheromone (GO:0019236)3.71228504
49oogenesis (GO:0048477)3.71035090
50negative regulation of cAMP-mediated signaling (GO:0043951)3.70626007
51synaptonemal complex organization (GO:0070193)3.59716168
52regulation of meiosis (GO:0040020)3.59561618
53somite rostral/caudal axis specification (GO:0032525)3.52911283
54male meiosis (GO:0007140)3.48614654
55energy homeostasis (GO:0097009)3.47182485
56sensory perception of smell (GO:0007608)3.46414180
57microtubule-based movement (GO:0007018)3.42301163
58piRNA metabolic process (GO:0034587)3.41486777
59meiotic nuclear division (GO:0007126)3.37733328
60regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.36789853
61sperm capacitation (GO:0048240)3.34588022
62intraciliary transport (GO:0042073)3.33539673
63reproduction (GO:0000003)3.31816269
64sperm-egg recognition (GO:0035036)3.31319233
65spermatid nucleus differentiation (GO:0007289)3.30684922
66negative regulation of histone methylation (GO:0031061)3.30487476
67microtubule bundle formation (GO:0001578)3.30113149
68negative regulation of reproductive process (GO:2000242)3.28633872
69plasma membrane fusion (GO:0045026)3.28263920
70genitalia morphogenesis (GO:0035112)3.27903930
71cilium assembly (GO:0042384)3.24397721
72positive regulation of chromosome segregation (GO:0051984)3.22452599
73regulation of cell communication by electrical coupling (GO:0010649)3.22297097
74membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.22205810
75ventricular system development (GO:0021591)3.20521089
76cilium organization (GO:0044782)3.20299981
77inner ear receptor stereocilium organization (GO:0060122)3.20285979
78detection of calcium ion (GO:0005513)3.19538951
79detection of molecule of bacterial origin (GO:0032490)3.14320639
80aminoglycoside antibiotic metabolic process (GO:0030647)3.12904714
81phosphorelay signal transduction system (GO:0000160)3.12716172
82regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.12222781
83single fertilization (GO:0007338)3.10842817
84pyrimidine dimer repair (GO:0006290)3.09889053
85regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.09839748
86meiosis I (GO:0007127)3.08345081
87regulation of meiotic cell cycle (GO:0051445)3.08213818
88urinary tract smooth muscle contraction (GO:0014848)3.07961407
89labyrinthine layer development (GO:0060711)3.07749332
90meiotic cell cycle process (GO:1903046)3.07398643
91cell-cell recognition (GO:0009988)3.06675130
92nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)3.05524365
93dopamine biosynthetic process (GO:0042416)3.03395107
94CENP-A containing nucleosome assembly (GO:0034080)3.03135337
95G-protein coupled receptor internalization (GO:0002031)3.02709656
96establishment of chromosome localization (GO:0051303)3.01288669
97sulfate transmembrane transport (GO:1902358)3.01204311
98positive regulation of cellular amide metabolic process (GO:0034250)2.99529015
99microtubule polymerization or depolymerization (GO:0031109)2.99034115
100cellular component assembly involved in morphogenesis (GO:0010927)2.98111263
101L-amino acid import (GO:0043092)2.97029455
102oxygen transport (GO:0015671)2.93701654
103regulation of double-strand break repair via homologous recombination (GO:0010569)2.91207987
104regulation of sarcomere organization (GO:0060297)2.90158917
105vitamin transmembrane transport (GO:0035461)2.90065967
106nucleus organization (GO:0006997)2.89920652
107translesion synthesis (GO:0019985)2.89120445
108centriole assembly (GO:0098534)2.87315708
109membrane depolarization during action potential (GO:0086010)2.86610361
110spermatogenesis (GO:0007283)2.83569946
111DNA methylation involved in gamete generation (GO:0043046)2.82484316
112germ cell development (GO:0007281)2.82315593
113male gamete generation (GO:0048232)2.82187395
114gamete generation (GO:0007276)2.79718266
115cardiac myofibril assembly (GO:0055003)2.79542840
116regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.79322993
117regulation of mitotic spindle checkpoint (GO:1903504)2.79322993
118regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.78833798
119spermatid development (GO:0007286)2.78770196
120positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.78691698
121regulation of relaxation of muscle (GO:1901077)2.78454176
122smoothened signaling pathway (GO:0007224)2.78124244
123regulation of microtubule-based movement (GO:0060632)2.77280728
124positive regulation of action potential (GO:0045760)2.77037757
125cell projection assembly (GO:0030031)2.76611977
126retinal rod cell development (GO:0046548)2.76554740
127synaptic vesicle docking involved in exocytosis (GO:0016081)2.74118556
128cytoplasmic microtubule organization (GO:0031122)2.73817209
129chromatin remodeling at centromere (GO:0031055)2.72699118
130gene silencing (GO:0016458)2.72412992
131calcium ion-dependent exocytosis (GO:0017156)2.72041843
132myofibril assembly (GO:0030239)2.68938636
133regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.68926467
134startle response (GO:0001964)2.67784224
135cilium morphogenesis (GO:0060271)2.66889676
136sulfate transport (GO:0008272)2.66101742
137negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.65179499
138protein polyglutamylation (GO:0018095)2.64178628
139regulation of membrane repolarization (GO:0060306)2.61748738
140microtubule depolymerization (GO:0007019)2.58965063
141left/right axis specification (GO:0070986)2.58961780
142regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.56574421
143microtubule severing (GO:0051013)2.55961430
144negative regulation of synaptic transmission, GABAergic (GO:0032229)2.55060367
145vocalization behavior (GO:0071625)2.52303966
146calcium ion import (GO:0070509)2.49932725
147binding of sperm to zona pellucida (GO:0007339)2.48866693
148negative regulation of skeletal muscle tissue development (GO:0048642)2.48236724
149G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.48009486
150behavioral response to ethanol (GO:0048149)2.47674697
151positive regulation of vascular permeability (GO:0043117)2.47533716
152neuron cell-cell adhesion (GO:0007158)2.46567081
153cardiac chamber formation (GO:0003207)2.45507511
154regulation of action potential (GO:0098900)2.42169246
155cardiac conduction (GO:0061337)2.41762198
156cardiac ventricle formation (GO:0003211)2.40513951
157atrial cardiac muscle cell action potential (GO:0086014)2.38784803
158negative regulation of systemic arterial blood pressure (GO:0003085)2.37992310
159positive regulation of CREB transcription factor activity (GO:0032793)2.35724341
160positive regulation of neurotransmitter secretion (GO:0001956)2.34564183
161negative regulation of cytosolic calcium ion concentration (GO:0051481)2.32852232
162cAMP catabolic process (GO:0006198)2.32600091
163left/right pattern formation (GO:0060972)2.32501199
164regulation of actin filament-based movement (GO:1903115)2.31407298
165neurotransmitter-gated ion channel clustering (GO:0072578)2.30616316
166fertilization (GO:0009566)2.30043752
167presynaptic membrane organization (GO:0097090)2.28496186
168nonmotile primary cilium assembly (GO:0035058)2.28383694
169regulation of cardiac muscle contraction (GO:0055117)2.28065650

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.28660530
2EZH2_22144423_ChIP-Seq_EOC_Human4.83020214
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.11220168
4GBX2_23144817_ChIP-Seq_PC3_Human3.67610716
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.25378309
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.08675340
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.84684212
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.43865390
9PCGF2_27294783_Chip-Seq_ESCs_Mouse2.41460354
10TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.31932684
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.26012089
12TAF15_26573619_Chip-Seq_HEK293_Human2.08806159
13BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.00640764
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.96864453
15SUZ12_27294783_Chip-Seq_NPCs_Mouse1.93694936
16CBX2_27304074_Chip-Seq_ESCs_Mouse1.93219575
17VDR_22108803_ChIP-Seq_LS180_Human1.87640890
18KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.83930725
19KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.83930725
20KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.83930725
21NFE2_27457419_Chip-Seq_LIVER_Mouse1.82498736
22POU3F2_20337985_ChIP-ChIP_501MEL_Human1.82382990
23PCGF2_27294783_Chip-Seq_NPCs_Mouse1.82037662
24SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.78821971
25IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.73968631
26CBP_20019798_ChIP-Seq_JUKART_Human1.73968631
27P300_19829295_ChIP-Seq_ESCs_Human1.73783712
28PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.72025058
29TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.71196004
30HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.70880689
31SMAD4_21799915_ChIP-Seq_A2780_Human1.70565193
32SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.68350410
33ZNF274_21170338_ChIP-Seq_K562_Hela1.68273182
34EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.66740251
35NANOG_18555785_Chip-Seq_ESCs_Mouse1.64393282
36BMI1_23680149_ChIP-Seq_NPCS_Mouse1.63086280
37IRF1_19129219_ChIP-ChIP_H3396_Human1.62247301
38E2F1_18555785_Chip-Seq_ESCs_Mouse1.60015701
39JARID2_20064375_ChIP-Seq_MESCs_Mouse1.58418252
40EWS_26573619_Chip-Seq_HEK293_Human1.58031366
41EZH2_27304074_Chip-Seq_ESCs_Mouse1.56311426
42* DROSHA_22980978_ChIP-Seq_HELA_Human1.56219753
43TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.56131851
44POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.56131851
45P53_22387025_ChIP-Seq_ESCs_Mouse1.56085267
46SUZ12_18555785_Chip-Seq_ESCs_Mouse1.53667660
47RNF2_27304074_Chip-Seq_NSC_Mouse1.51866384
48CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51147933
49STAT3_18555785_Chip-Seq_ESCs_Mouse1.50419067
50* EZH2_27294783_Chip-Seq_NPCs_Mouse1.50276804
51PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.48676428
52ER_23166858_ChIP-Seq_MCF-7_Human1.48619332
53EED_16625203_ChIP-ChIP_MESCs_Mouse1.48522584
54* REST_21632747_ChIP-Seq_MESCs_Mouse1.48467404
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.47698681
56SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.47200892
57SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.46230628
58SALL1_21062744_ChIP-ChIP_HESCs_Human1.46210309
59SMAD_19615063_ChIP-ChIP_OVARY_Human1.45259676
60IGF1R_20145208_ChIP-Seq_DFB_Human1.44360454
61EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.43921500
62CMYC_18555785_Chip-Seq_ESCs_Mouse1.43789975
63SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.42759619
64FOXM1_26456572_ChIP-Seq_MCF-7_Human1.41743839
65CDX2_19796622_ChIP-Seq_MESCs_Mouse1.41619408
66CTBP1_25329375_ChIP-Seq_LNCAP_Human1.41478978
67* PRDM14_20953172_ChIP-Seq_ESCs_Human1.41189271
68SMAD3_21741376_ChIP-Seq_EPCs_Human1.39845248
69CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.39674268
70EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.39312164
71P300_18555785_Chip-Seq_ESCs_Mouse1.34475043
72SOX2_18555785_Chip-Seq_ESCs_Mouse1.34411346
73EZH2_27294783_Chip-Seq_ESCs_Mouse1.33920622
74OCT4_18555785_Chip-Seq_ESCs_Mouse1.33818293
75SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.32794433
76RNF2_18974828_ChIP-Seq_MESCs_Mouse1.32694253
77EZH2_18974828_ChIP-Seq_MESCs_Mouse1.32694253
78* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.32662800
79AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32649502
80NMYC_18555785_Chip-Seq_ESCs_Mouse1.32288942
81SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.32025647
82SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31930197
83AHR_22903824_ChIP-Seq_MCF-7_Human1.31663406
84RNF2_27304074_Chip-Seq_ESCs_Mouse1.31480242
85TAL1_26923725_Chip-Seq_HPCs_Mouse1.31044059
86* TCF4_23295773_ChIP-Seq_U87_Human1.30000885
87RUNX1_27457419_Chip-Seq_LIVER_Mouse1.29823487
88NR3C1_21868756_ChIP-Seq_MCF10A_Human1.29176077
89* STAT3_23295773_ChIP-Seq_U87_Human1.28354547
90UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.28072041
91* PIAS1_25552417_ChIP-Seq_VCAP_Human1.26858607
92PU1_27457419_Chip-Seq_LIVER_Mouse1.26605911
93FUS_26573619_Chip-Seq_HEK293_Human1.26097422
94TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25014973
95ARNT_22903824_ChIP-Seq_MCF-7_Human1.24701904
96ZFX_18555785_Chip-Seq_ESCs_Mouse1.24337947
97SUZ12_27294783_Chip-Seq_ESCs_Mouse1.23041874
98SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.22806817
99GATA1_26923725_Chip-Seq_HPCs_Mouse1.22524669
100SMAD4_21741376_ChIP-Seq_EPCs_Human1.22172798
101KDM2B_26808549_Chip-Seq_REH_Human1.22094869
102MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.21057435
103MTF2_20144788_ChIP-Seq_MESCs_Mouse1.20764589
104CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.20479290
105JARID2_20075857_ChIP-Seq_MESCs_Mouse1.19625467
106KLF4_18555785_Chip-Seq_ESCs_Mouse1.19222468
107TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18496476
108CTCF_18555785_Chip-Seq_ESCs_Mouse1.18480276
109KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.17979528
110ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.17614810
111BCAT_22108803_ChIP-Seq_LS180_Human1.17425987
112ESRRB_18555785_Chip-Seq_ESCs_Mouse1.16808405
113RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.15601067
114HTT_18923047_ChIP-ChIP_STHdh_Human1.15250697
115* CRX_20693478_ChIP-Seq_RETINA_Mouse1.13901184
116* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13368475
117AR_25329375_ChIP-Seq_VCAP_Human1.12520265
118* OCT4_21477851_ChIP-Seq_ESCs_Mouse1.12176655
119BP1_19119308_ChIP-ChIP_Hs578T_Human1.11505122
120LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11364743
121NANOG_19829295_ChIP-Seq_ESCs_Human1.10931886
122SOX2_19829295_ChIP-Seq_ESCs_Human1.10931886
123CBP_21632823_ChIP-Seq_H3396_Human1.10804847
124* EP300_21415370_ChIP-Seq_HL-1_Mouse1.10673320
125TCF4_22108803_ChIP-Seq_LS180_Human1.09953074
126* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.09689204
127SMRT_27268052_Chip-Seq_Bcells_Human1.09553115
128EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.09446098
129OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09273513
130RUNX2_22187159_ChIP-Seq_PCA_Human1.08386672
131MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.08274335
132STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.07162839
133CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.07046809
134SMAD1_18555785_Chip-Seq_ESCs_Mouse1.06689767
135NANOG_20526341_ChIP-Seq_ESCs_Human1.00849950
136SOX2_21211035_ChIP-Seq_LN229_Gbm0.98392378
137TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.97764938
138TP53_22573176_ChIP-Seq_HFKS_Human0.96633960
139GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.96148468
140* ZNF217_24962896_ChIP-Seq_MCF-7_Human0.95682536
141* FOXA1_27270436_Chip-Seq_PROSTATE_Human0.94538984
142* FOXA1_25329375_ChIP-Seq_VCAP_Human0.94538984
143TP53_18474530_ChIP-ChIP_U2OS_Human0.93911299
144NOTCH1_21737748_ChIP-Seq_TLL_Human0.93815087
145* SALL4_22934838_ChIP-ChIP_CD34+_Human0.92671696
146STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.92417355
147MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.91947933
148CDX2_22108803_ChIP-Seq_LS180_Human0.90773440
149LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90767010
150* FOXA1_21572438_ChIP-Seq_LNCaP_Human0.88684565
151NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.88495759
152JUN_21703547_ChIP-Seq_K562_Human0.87378817

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003718_maternal_effect6.67598474
2MP0008789_abnormal_olfactory_epithelium4.96215506
3MP0005499_abnormal_olfactory_system4.15995490
4MP0005394_taste/olfaction_phenotype4.15995490
5MP0001984_abnormal_olfaction3.90048283
6MP0003646_muscle_fatigue3.75254279
7MP0005410_abnormal_fertilization3.74838629
8MP0005645_abnormal_hypothalamus_physiol3.26354622
9MP0003890_abnormal_embryonic-extraembry3.18754968
10MP0002653_abnormal_ependyma_morphology3.05011611
11MP0005646_abnormal_pituitary_gland2.89358377
12MP0005395_other_phenotype2.86995609
13MP0010030_abnormal_orbit_morphology2.55994037
14MP0001188_hyperpigmentation2.45556006
15MP0002837_dystrophic_cardiac_calcinosis2.40818667
16MP0008004_abnormal_stomach_pH2.37095660
17MP0000566_synostosis2.34656690
18MP0004215_abnormal_myocardial_fiber2.32589316
19MP0002139_abnormal_hepatobiliary_system2.26621484
20MP0002234_abnormal_pharynx_morphology2.17028066
21MP0010234_abnormal_vibrissa_follicle2.11333800
22MP0005171_absent_coat_pigmentation2.04974222
23MP0008877_abnormal_DNA_methylation2.02401962
24MP0009046_muscle_twitch1.99851325
25MP0002735_abnormal_chemical_nociception1.99451607
26MP0006292_abnormal_olfactory_placode1.92370652
27MP0002102_abnormal_ear_morphology1.91516499
28MP0003787_abnormal_imprinting1.91377306
29MP0006276_abnormal_autonomic_nervous1.89541819
30MP0000751_myopathy1.89465217
31MP0003880_abnormal_central_pattern1.87745026
32MP0004510_myositis1.85970838
33MP0002928_abnormal_bile_duct1.80041314
34MP0003136_yellow_coat_color1.76680793
35MP0002822_catalepsy1.75752880
36MP0004084_abnormal_cardiac_muscle1.73145095
37MP0002138_abnormal_hepatobiliary_system1.72957845
38MP0003698_abnormal_male_reproductive1.71856809
39MP0003699_abnormal_female_reproductive1.71170545
40MP0003878_abnormal_ear_physiology1.71144481
41MP0005377_hearing/vestibular/ear_phenot1.71144481
42MP0002638_abnormal_pupillary_reflex1.69642942
43MP0001486_abnormal_startle_reflex1.66969553
44MP0009697_abnormal_copulation1.66240120
45MP0001293_anophthalmia1.65753639
46MP0004484_altered_response_of1.65634349
47MP0004036_abnormal_muscle_relaxation1.60734538
48MP0000653_abnormal_sex_gland1.60590554
49MP0005423_abnormal_somatic_nervous1.59482315
50MP0010386_abnormal_urinary_bladder1.59058872
51MP0009745_abnormal_behavioral_response1.54977275
52MP0008875_abnormal_xenobiotic_pharmacok1.49897387
53MP0002736_abnormal_nociception_after1.47383741
54MP0008995_early_reproductive_senescence1.47016649
55MP0002233_abnormal_nose_morphology1.46527450
56MP0000631_abnormal_neuroendocrine_gland1.45088189
57MP0004085_abnormal_heartbeat1.44731395
58MP0003879_abnormal_hair_cell1.44450452
59MP0002572_abnormal_emotion/affect_behav1.44141027
60MP0001968_abnormal_touch/_nociception1.43752224
61MP0001145_abnormal_male_reproductive1.43143380
62MP0002132_abnormal_respiratory_system1.41758201
63MP0004742_abnormal_vestibular_system1.37314605
64MP0004043_abnormal_pH_regulation1.34624753
65MP0009780_abnormal_chondrocyte_physiolo1.34296203
66MP0002557_abnormal_social/conspecific_i1.34217286
67MP0003635_abnormal_synaptic_transmissio1.30013558
68MP0005389_reproductive_system_phenotype1.29591904
69MP0002972_abnormal_cardiac_muscle1.29337454
70MP0005360_urolithiasis1.29129448
71MP0008057_abnormal_DNA_replication1.28635089
72MP0001986_abnormal_taste_sensitivity1.27955338
73MP0003252_abnormal_bile_duct1.27574815
74MP0002277_abnormal_respiratory_mucosa1.26192697
75MP0010678_abnormal_skin_adnexa1.25246488
76MP0004859_abnormal_synaptic_plasticity1.24817897
77MP0002067_abnormal_sensory_capabilities1.24758925
78MP0001929_abnormal_gametogenesis1.22759838
79MP0000569_abnormal_digit_pigmentation1.22229187
80MP0005670_abnormal_white_adipose1.21394454
81MP0001440_abnormal_grooming_behavior1.21231508
82MP0008058_abnormal_DNA_repair1.19285408
83MP0002063_abnormal_learning/memory/cond1.19033678
84MP0001502_abnormal_circadian_rhythm1.18652712
85MP0003137_abnormal_impulse_conducting1.18498472
86MP0002272_abnormal_nervous_system1.16384109
87MP0002064_seizures1.16285234
88MP0001485_abnormal_pinna_reflex1.16192179
89MP0001501_abnormal_sleep_pattern1.15769701
90MP0004142_abnormal_muscle_tone1.14890298
91MP0005085_abnormal_gallbladder_physiolo1.13860844
92MP0001529_abnormal_vocalization1.13740515
93MP0005409_darkened_coat_color1.13065802
94MP0002734_abnormal_mechanical_nocicepti1.11874253
95MP0003195_calcinosis1.09725916
96MP0002184_abnormal_innervation1.08841752
97MP0002876_abnormal_thyroid_physiology1.07443967
98MP0003950_abnormal_plasma_membrane1.05354908
99MP0000015_abnormal_ear_pigmentation1.04832766
100MP0006072_abnormal_retinal_apoptosis1.03944875
101MP0003941_abnormal_skin_development1.03518441
102MP0002210_abnormal_sex_determination1.03034564
103MP0004924_abnormal_behavior1.02696260
104MP0005386_behavior/neurological_phenoty1.02696260
105MP0005620_abnormal_muscle_contractility1.00909860
106MP0000749_muscle_degeneration1.00701639
107MP0003121_genomic_imprinting1.00250670
108MP0000427_abnormal_hair_cycle0.99572040
109MP0008775_abnormal_heart_ventricle0.98571797
110MP0000778_abnormal_nervous_system0.98417205
111MP0003077_abnormal_cell_cycle0.97565225
112MP0003828_pulmonary_edema0.97342522
113MP0002127_abnormal_cardiovascular_syste0.96645271
114MP0001963_abnormal_hearing_physiology0.96230038
115MP0000762_abnormal_tongue_morphology0.94692520
116MP0004133_heterotaxia0.94015148
117MP0002160_abnormal_reproductive_system0.93376261
118MP0005551_abnormal_eye_electrophysiolog0.92342295
119MP0000026_abnormal_inner_ear0.92339872
120MP0001324_abnormal_eye_pigmentation0.92287653
121MP0002163_abnormal_gland_morphology0.91513769
122MP0001970_abnormal_pain_threshold0.91259101
123MP0000383_abnormal_hair_follicle0.88513658
124MP0003693_abnormal_embryo_hatching0.88351754
125MP0005647_abnormal_sex_gland0.88226482
126MP0006138_congestive_heart_failure0.88060965
127MP0005253_abnormal_eye_physiology0.86544931
128MP0001119_abnormal_female_reproductive0.84912382
129MP0005310_abnormal_salivary_gland0.83353672
130MP0003183_abnormal_peptide_metabolism0.82573374
131MP0002106_abnormal_muscle_physiology0.81587065
132MP0000049_abnormal_middle_ear0.80884322
133MP0002090_abnormal_vision0.80515421
134MP0003656_abnormal_erythrocyte_physiolo0.80388404
135MP0003119_abnormal_digestive_system0.80255342
136MP0001905_abnormal_dopamine_level0.80239304
137MP0004270_analgesia0.78635832
138MP0000372_irregular_coat_pigmentation0.75903525
139MP0002161_abnormal_fertility/fecundity0.73451519
140MP0010094_abnormal_chromosome_stability0.73136107
141MP0005379_endocrine/exocrine_gland_phen0.69767032
142MP0005330_cardiomyopathy0.68689649
143MP0005623_abnormal_meninges_morphology0.68394700
144MP0005369_muscle_phenotype0.68256305
145MP0000678_abnormal_parathyroid_gland0.67952998
146MP0002752_abnormal_somatic_nervous0.67233503
147MP0008932_abnormal_embryonic_tissue0.65776242
148MP0004019_abnormal_vitamin_homeostasis0.65279819
149MP0005174_abnormal_tail_pigmentation0.65183439
150MP0000538_abnormal_urinary_bladder0.64456346
151MP0000681_abnormal_thyroid_gland0.63570704
152MP0005391_vision/eye_phenotype0.62513681
153MP0005195_abnormal_posterior_eye0.62106572
154MP0010307_abnormal_tumor_latency0.58846101
155MP0002751_abnormal_autonomic_nervous0.55705546
156MP0002229_neurodegeneration0.54212853
157MP0001756_abnormal_urination0.52671789
158MP0005187_abnormal_penis_morphology0.52004853
159MP0001664_abnormal_digestion0.51377082
160MP0002282_abnormal_trachea_morphology0.48563899
161MP0002909_abnormal_adrenal_gland0.46799388
162MP0001286_abnormal_eye_development0.45664087

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)7.93168827
2Dynein arm defect of respiratory motile cilia (HP:0012255)7.47720210
3Absent/shortened dynein arms (HP:0200106)7.47720210
4Abnormal respiratory motile cilium physiology (HP:0012261)6.89989285
5Abnormal ciliary motility (HP:0012262)6.70508643
6Abnormal respiratory epithelium morphology (HP:0012253)6.17714257
7Abnormal respiratory motile cilium morphology (HP:0005938)6.17714257
8Supernumerary spleens (HP:0009799)5.80143811
9Rhinitis (HP:0012384)5.64044089
10Male infertility (HP:0003251)3.75264653
11Oligodactyly (hands) (HP:0001180)3.63332064
12Atrial fibrillation (HP:0005110)3.36496543
13Abnormality of abdominal situs (HP:0011620)3.29369949
14Abdominal situs inversus (HP:0003363)3.29369949
15Nephronophthisis (HP:0000090)3.29045198
16Chronic hepatic failure (HP:0100626)3.28961757
17Tubulointerstitial nephritis (HP:0001970)3.19642977
18Febrile seizures (HP:0002373)3.18374814
19Medial flaring of the eyebrow (HP:0010747)3.18225893
20Primary atrial arrhythmia (HP:0001692)3.17033825
21Chronic bronchitis (HP:0004469)3.16955611
22Abnormality of the nasal mucosa (HP:0000433)3.06170213
23Pancreatic fibrosis (HP:0100732)3.06094137
24Septo-optic dysplasia (HP:0100842)3.03958454
25Facial hemangioma (HP:0000329)3.02895723
26Bronchiectasis (HP:0002110)3.00180043
27Supraventricular tachycardia (HP:0004755)2.99928583
28Molar tooth sign on MRI (HP:0002419)2.92052169
29Abnormality of midbrain morphology (HP:0002418)2.92052169
30True hermaphroditism (HP:0010459)2.90791938
31Osteomalacia (HP:0002749)2.89555164
32Supraventricular arrhythmia (HP:0005115)2.85767985
33Abnormality of the labia minora (HP:0012880)2.81987631
34Abnormality of the renal medulla (HP:0100957)2.77998676
35Sudden death (HP:0001699)2.76882572
36Short tibia (HP:0005736)2.76345836
37Absent eyebrow (HP:0002223)2.74646599
38Focal motor seizures (HP:0011153)2.74407422
39Nephrogenic diabetes insipidus (HP:0009806)2.67862349
40Bronchitis (HP:0012387)2.64659422
41Azoospermia (HP:0000027)2.60969139
42Aplasia/Hypoplasia of the tibia (HP:0005772)2.59862171
43Gait imbalance (HP:0002141)2.58581146
44Chromosomal breakage induced by crosslinking agents (HP:0003221)2.56517073
45Anencephaly (HP:0002323)2.53942351
46Absent septum pellucidum (HP:0001331)2.53347450
47Congenital primary aphakia (HP:0007707)2.53265969
48Oligodactyly (HP:0012165)2.52208032
49Syncope (HP:0001279)2.51660261
50Prostate neoplasm (HP:0100787)2.36445638
51Cholecystitis (HP:0001082)2.34201613
52Abnormal gallbladder physiology (HP:0012438)2.34201613
53Gonadotropin excess (HP:0000837)2.30885498
54Congenital hepatic fibrosis (HP:0002612)2.28087206
55Infertility (HP:0000789)2.27211356
56Left ventricular hypertrophy (HP:0001712)2.26192757
57Papillary thyroid carcinoma (HP:0002895)2.24534734
58Ventricular tachycardia (HP:0004756)2.22042895
59Hypothermia (HP:0002045)2.21510185
60Retinal dysplasia (HP:0007973)2.17950217
61Abnormal biliary tract physiology (HP:0012439)2.17879040
62Bile duct proliferation (HP:0001408)2.17879040
63Chronic sinusitis (HP:0011109)2.17180466
64Chromsome breakage (HP:0040012)2.17173506
65Calf muscle hypertrophy (HP:0008981)2.16902746
66Lip pit (HP:0100267)2.14613181
67Abnormality of the septum pellucidum (HP:0007375)2.13893476
68Occipital encephalocele (HP:0002085)2.13575346
69Recurrent otitis media (HP:0000403)2.13317297
70Postaxial foot polydactyly (HP:0001830)2.10226711
71Malnutrition (HP:0004395)2.09860271
72Recurrent sinusitis (HP:0011108)2.08453581
73Abnormal hair whorl (HP:0010721)2.07432014
74Poor coordination (HP:0002370)2.06618520
75Congenital sensorineural hearing impairment (HP:0008527)2.05473218
76Prolonged QT interval (HP:0001657)2.04778683
77Optic neuritis (HP:0100653)2.03386857
78Retrobulbar optic neuritis (HP:0100654)2.03386857
79Renal dysplasia (HP:0000110)1.99998402
80Hypophosphatemic rickets (HP:0004912)1.98587693
81Muscle hypertrophy of the lower extremities (HP:0008968)1.98519358
82Aplasia/Hypoplasia of the lens (HP:0008063)1.97286396
83Median cleft lip (HP:0000161)1.96648908
84Epileptic encephalopathy (HP:0200134)1.95928087
85Decreased central vision (HP:0007663)1.95656890
86Genital tract atresia (HP:0001827)1.95050366
87Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.94587188
88Abnormal spermatogenesis (HP:0008669)1.93415832
89Postaxial hand polydactyly (HP:0001162)1.93410012
90Hypoplasia of the fovea (HP:0007750)1.91662196
91Aplasia/Hypoplasia of the fovea (HP:0008060)1.91662196
92Oculomotor apraxia (HP:0000657)1.91367715
93Abnormality of the renal cortex (HP:0011035)1.89661647
94Pancreatic cysts (HP:0001737)1.88626939
95Tubulointerstitial abnormality (HP:0001969)1.86781652
96Bundle branch block (HP:0011710)1.85509673
97Abolished electroretinogram (ERG) (HP:0000550)1.84768936
98Anterior segment dysgenesis (HP:0007700)1.83838090
99Abnormality of the right ventricle (HP:0001707)1.83256640
100Nasal polyposis (HP:0100582)1.82912561
101Maternal diabetes (HP:0009800)1.82451149
102Vaginal atresia (HP:0000148)1.82394227
103Cone-rod dystrophy (HP:0000548)1.82284074
104Hyperventilation (HP:0002883)1.82162566
105Duplicated collecting system (HP:0000081)1.81835363
106Bradycardia (HP:0001662)1.81631675
107Enlarged penis (HP:0000040)1.80871592
108Fair hair (HP:0002286)1.80869105
109Abnormality of the renal collecting system (HP:0004742)1.80475373
110White forelock (HP:0002211)1.80462685
111Wrist flexion contracture (HP:0001239)1.80096336
112Bell-shaped thorax (HP:0001591)1.79270378
113Cystic liver disease (HP:0006706)1.78727673
114Abnormal EKG (HP:0003115)1.78185877
115Abnormality of the calf musculature (HP:0001430)1.77725229
116Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.76440053
117Abnormality of the fovea (HP:0000493)1.75300740
118Abnormality of molar (HP:0011077)1.75095855
119Abnormality of molar morphology (HP:0011070)1.75095855
120Hyperactive renin-angiotensin system (HP:0000841)1.74505208
121Aplasia/Hypoplasia of the tongue (HP:0010295)1.73206555
122Tubular atrophy (HP:0000092)1.72599086
123Patchy hypopigmentation of hair (HP:0011365)1.71950081
124Stillbirth (HP:0003826)1.69209336
125Pulmonary artery stenosis (HP:0004415)1.68236795
126Unilateral renal agenesis (HP:0000122)1.66992354
127Abnormality of the dental root (HP:0006486)1.66622919
128Taurodontia (HP:0000679)1.66622919
129Abnormality of permanent molar morphology (HP:0011071)1.66622919
130Preaxial hand polydactyly (HP:0001177)1.65768728
131Aganglionic megacolon (HP:0002251)1.63771149
132Abnormality of dental color (HP:0011073)1.63569540
133Dyschromatopsia (HP:0007641)1.62318315
134Sclerocornea (HP:0000647)1.61688169
135Abnormality of incisor morphology (HP:0011063)1.61447184
136Exercise-induced myalgia (HP:0003738)1.61147274
137Heart block (HP:0012722)1.60777227
138Impulsivity (HP:0100710)1.60640653
139Male pseudohermaphroditism (HP:0000037)1.60070511
140Hyperphosphatemia (HP:0002905)1.60058659
141Optic nerve hypoplasia (HP:0000609)1.60039016
142Follicular hyperkeratosis (HP:0007502)1.58896782
143Astigmatism (HP:0000483)1.56505215
144Abnormality of the dental pulp (HP:0006479)1.56354407
145Absent eyelashes (HP:0000561)1.54950801
146Intrahepatic cholestasis (HP:0001406)1.52148546
147Abnormal rod and cone electroretinograms (HP:0008323)1.49761731
148Abnormality of the phalanges of the hallux (HP:0010057)1.47891053
149Dysdiadochokinesis (HP:0002075)1.47873038
150Metaphyseal irregularity (HP:0003025)1.45938882
151Chronic otitis media (HP:0000389)1.45455353
152Absent rod-and cone-mediated responses on ERG (HP:0007688)1.43647761
153Narrow forehead (HP:0000341)1.42456020
154Retinitis pigmentosa (HP:0000510)1.41524398
155Truncal obesity (HP:0001956)1.41129863

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K94.76004918
2ARAF4.31084183
3MAP3K134.13537041
4CASK4.12827140
5SIK33.48465048
6PDK42.98675340
7PDK32.98675340
8MAP2K72.69090811
9CDK92.57723025
10LMTK22.57316868
11PHKG22.43241088
12PHKG12.43241088
13MST42.32826425
14BRAF2.20623939
15TNIK2.11811068
16GRK72.08708973
17TTK1.99002281
18PDK21.97803504
19PRPF4B1.97272696
20KSR21.96031153
21BMPR21.93106489
22SGK21.92201097
23MET1.87973590
24MOS1.82328821
25ZAK1.81903212
26TAOK31.80700995
27RAF11.77723407
28MUSK1.76201199
29INSRR1.76077646
30MAPK131.69290004
31CDK81.68277699
32AURKA1.58109973
33STK38L1.56505254
34EIF2AK31.54271144
35TXK1.53189987
36PRKCI1.51014759
37MAP3K41.50417272
38SIK21.46064895
39BMPR1B1.45633573
40PNCK1.35554557
41ERBB31.32137182
42NEK91.31812910
43STK391.30016558
44WNK31.29708179
45SGK2231.25632474
46SGK4941.25632474
47NTRK21.25036554
48KSR11.24239903
49CDK31.23982918
50PLK21.23792215
51PINK11.21547050
52IRAK11.20254006
53NTRK31.19880792
54AKT31.17893359
55YES11.17256064
56IRAK41.16939384
57ADRBK21.15115787
58MARK31.14764657
59PRKD31.13507659
60PTK2B1.11699124
61SGK31.11175401
62STK31.09560199
63MAP3K141.09487403
64PKN11.09157945
65MYLK1.08705129
66TRIM281.07561466
67STK381.06098544
68PLK11.06030249
69IRAK31.05493704
70VRK11.02187590
71MAPKAPK31.01387832
72BLK0.96826722
73DAPK20.96556661
74MAP4K20.94379092
75PLK40.91941644
76MARK10.89731031
77ACVR1B0.89530288
78EPHA40.88894591
79MAP3K60.87852613
80CCNB10.86600566
81CAMK2A0.85600226
82CAMK40.84349321
83STK240.83722055
84NUAK10.83462207
85EIF2AK20.81063634
86LATS10.80834920
87BRSK20.80560699
88TTN0.80145752
89PRKCE0.78400814
90CSNK1G10.77381963
91MAPK150.76261838
92IRAK20.76016433
93CDK70.75380861
94CAMK2D0.73606436
95TNK20.73219276
96DMPK0.71885360
97PIK3CA0.71767119
98PLK30.70443885
99CSNK1G20.69980169
100OBSCN0.69693431
101TSSK60.64787009
102MELK0.64110494
103TRPM70.62568389
104SIK10.61188375
105MAPK70.61031370
106TEC0.59925384
107CDC70.59101044
108EPHA30.57960773
109GRK50.57460802
110PIM10.56962703
111SGK10.56513573
112OXSR10.55998832
113TIE10.55641966
114GRK10.55021241
115WNK10.54973538
116FRK0.54555970
117CSNK1G30.54244176
118MAP3K120.52298578
119TGFBR10.52056160
120CAMK10.51241381
121MAP3K80.50698145
122MKNK20.49004339
123BCR0.48683244
124CSNK1A1L0.48112868
125NME10.48111878
126NEK60.47715905
127PRKG10.47206516
128IKBKE0.46360846
129MAPK120.45163535
130CDK120.44974588
131PRKCG0.44494289
132CSNK1D0.43713998
133TGFBR20.42741826
134CDK20.42495813
135MAP2K40.42132001
136LRRK20.41922295
137ATM0.40567090
138CDK190.38580721
139PRKAA20.38411682
140JAK10.38054709
141PRKACA0.37532635
142PRKAA10.37186842
143RPS6KA20.36236920
144SRPK10.35795559
145PRKCZ0.34760876
146CAMK2B0.34012994
147MAP3K50.33621931
148CHEK10.33083805
149ADRBK10.32959460
150BRSK10.32923880
151EGFR0.32579579
152MARK20.31800698
153PRKACB0.31670009
154RIPK40.31660053
155CDK50.30861637
156CDK10.30708523
157PDK10.30102232
158NEK20.29972833
159WNK40.29341601
160CAMK1D0.28433464
161NLK0.25659850
162MAP3K20.23677524
163TLK10.22329691
164ATR0.21158232

Predicted pathways (KEGG)

RankGene SetZ-score
1Caffeine metabolism_Homo sapiens_hsa002324.00324467
2Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005333.83722484
3Olfactory transduction_Homo sapiens_hsa047403.78909352
4Cell cycle_Homo sapiens_hsa041102.95470159
5Nicotine addiction_Homo sapiens_hsa050332.86237566
6Oocyte meiosis_Homo sapiens_hsa041142.77761298
7Mismatch repair_Homo sapiens_hsa034302.55373574
8RNA degradation_Homo sapiens_hsa030182.52882852
9Taste transduction_Homo sapiens_hsa047422.31442041
10Folate biosynthesis_Homo sapiens_hsa007902.28027898
11Morphine addiction_Homo sapiens_hsa050322.13399187
12Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.96412466
13Cardiac muscle contraction_Homo sapiens_hsa042601.96407960
14Calcium signaling pathway_Homo sapiens_hsa040201.95620346
15Nucleotide excision repair_Homo sapiens_hsa034201.94785830
16Circadian entrainment_Homo sapiens_hsa047131.84383003
17Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.82656021
18Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.82432781
19Dilated cardiomyopathy_Homo sapiens_hsa054141.81480737
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.70971318
21Synaptic vesicle cycle_Homo sapiens_hsa047211.70585117
22ABC transporters_Homo sapiens_hsa020101.63050586
23Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.62052303
24Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.58746094
25Glutamatergic synapse_Homo sapiens_hsa047241.57002718
26Serotonergic synapse_Homo sapiens_hsa047261.54591998
27Base excision repair_Homo sapiens_hsa034101.50894765
28Homologous recombination_Homo sapiens_hsa034401.49158993
29Insulin secretion_Homo sapiens_hsa049111.42860415
30Amphetamine addiction_Homo sapiens_hsa050311.41204668
31Huntingtons disease_Homo sapiens_hsa050161.40824287
32SNARE interactions in vesicular transport_Homo sapiens_hsa041301.39667307
33Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.38342477
34Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.37466961
35Phototransduction_Homo sapiens_hsa047441.33423144
36Renin secretion_Homo sapiens_hsa049241.31231291
37Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.30697794
38Collecting duct acid secretion_Homo sapiens_hsa049661.30672116
39Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.30620573
40Regulation of autophagy_Homo sapiens_hsa041401.30420202
41Oxidative phosphorylation_Homo sapiens_hsa001901.29479784
42cAMP signaling pathway_Homo sapiens_hsa040241.29014280
43Chemical carcinogenesis_Homo sapiens_hsa052041.28860907
44Ovarian steroidogenesis_Homo sapiens_hsa049131.24503355
45GABAergic synapse_Homo sapiens_hsa047271.21909017
46Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.19845199
47Fanconi anemia pathway_Homo sapiens_hsa034601.17355520
48Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.15423928
49Salivary secretion_Homo sapiens_hsa049701.15248621
50Rheumatoid arthritis_Homo sapiens_hsa053231.15033007
51Fatty acid biosynthesis_Homo sapiens_hsa000611.14944361
52Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.11825428
53Histidine metabolism_Homo sapiens_hsa003401.10963973
54Cysteine and methionine metabolism_Homo sapiens_hsa002701.10891129
55RNA polymerase_Homo sapiens_hsa030201.10833282
56Cholinergic synapse_Homo sapiens_hsa047251.09218710
57Intestinal immune network for IgA production_Homo sapiens_hsa046721.07829510
58RNA transport_Homo sapiens_hsa030131.06212238
59Phosphatidylinositol signaling system_Homo sapiens_hsa040701.05894153
60Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.05665932
61cGMP-PKG signaling pathway_Homo sapiens_hsa040221.04236671
62Alzheimers disease_Homo sapiens_hsa050101.01150521
63Parkinsons disease_Homo sapiens_hsa050120.99517043
64Dopaminergic synapse_Homo sapiens_hsa047280.97013586
65Toll-like receptor signaling pathway_Homo sapiens_hsa046200.93989846
66Basal transcription factors_Homo sapiens_hsa030220.93477470
67p53 signaling pathway_Homo sapiens_hsa041150.92498518
68Propanoate metabolism_Homo sapiens_hsa006400.91428327
69Circadian rhythm_Homo sapiens_hsa047100.89942792
70Arachidonic acid metabolism_Homo sapiens_hsa005900.89379562
71Autoimmune thyroid disease_Homo sapiens_hsa053200.89197391
72Aldosterone synthesis and secretion_Homo sapiens_hsa049250.88309428
73Cocaine addiction_Homo sapiens_hsa050300.88043526
74Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.86987222
75Long-term potentiation_Homo sapiens_hsa047200.86964434
76Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.86874258
77Oxytocin signaling pathway_Homo sapiens_hsa049210.85841778
78Gap junction_Homo sapiens_hsa045400.85558168
79Gastric acid secretion_Homo sapiens_hsa049710.85543634
80Phenylalanine metabolism_Homo sapiens_hsa003600.84533955
81Protein export_Homo sapiens_hsa030600.83426284
82Type II diabetes mellitus_Homo sapiens_hsa049300.82498297
83Phagosome_Homo sapiens_hsa041450.82367593
84Fatty acid elongation_Homo sapiens_hsa000620.81736827
85Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.81655222
86Ether lipid metabolism_Homo sapiens_hsa005650.77130823
87NF-kappa B signaling pathway_Homo sapiens_hsa040640.76217223
88Axon guidance_Homo sapiens_hsa043600.74113306
89Glucagon signaling pathway_Homo sapiens_hsa049220.73989407
90Vascular smooth muscle contraction_Homo sapiens_hsa042700.72650587
91Maturity onset diabetes of the young_Homo sapiens_hsa049500.71323298
92Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.69492924
93Mineral absorption_Homo sapiens_hsa049780.68138159
94MAPK signaling pathway_Homo sapiens_hsa040100.67939914
95Ras signaling pathway_Homo sapiens_hsa040140.67620566
96Inositol phosphate metabolism_Homo sapiens_hsa005620.67557027
97Melanoma_Homo sapiens_hsa052180.67275281
98Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.66592456
99Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.65595099
100Sphingolipid metabolism_Homo sapiens_hsa006000.65261857
101Long-term depression_Homo sapiens_hsa047300.64212978
102Dorso-ventral axis formation_Homo sapiens_hsa043200.63743051
103Purine metabolism_Homo sapiens_hsa002300.63514062
104Hematopoietic cell lineage_Homo sapiens_hsa046400.62586051
105Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.62570887
106Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.61630451
107Measles_Homo sapiens_hsa051620.59896536
108Allograft rejection_Homo sapiens_hsa053300.59588298
109Glycosaminoglycan degradation_Homo sapiens_hsa005310.58993332
110Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.58980990
111Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.58865123
112Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.58506098
113Glutathione metabolism_Homo sapiens_hsa004800.58240241
114Retinol metabolism_Homo sapiens_hsa008300.57270175
115Osteoclast differentiation_Homo sapiens_hsa043800.57013909
116Tyrosine metabolism_Homo sapiens_hsa003500.56861596
117Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.56462423
118RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.56403173
119Hedgehog signaling pathway_Homo sapiens_hsa043400.54421582
120beta-Alanine metabolism_Homo sapiens_hsa004100.53739348
121Tuberculosis_Homo sapiens_hsa051520.53631866
122Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.53613202
123Vitamin digestion and absorption_Homo sapiens_hsa049770.52193426
124Linoleic acid metabolism_Homo sapiens_hsa005910.51040843
125Bile secretion_Homo sapiens_hsa049760.50386128
126Jak-STAT signaling pathway_Homo sapiens_hsa046300.49013711
127NOD-like receptor signaling pathway_Homo sapiens_hsa046210.48601108
128Chemokine signaling pathway_Homo sapiens_hsa040620.47569713
129Pancreatic secretion_Homo sapiens_hsa049720.46681868
130alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.46289370
131Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.45655176
132Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.44997617
133African trypanosomiasis_Homo sapiens_hsa051430.44135149
134Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.43764204
135Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.43447174
136Peroxisome_Homo sapiens_hsa041460.43283982
137Primary bile acid biosynthesis_Homo sapiens_hsa001200.41576536
138TNF signaling pathway_Homo sapiens_hsa046680.41410305
139Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.40210888
140Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.40093284
141Other glycan degradation_Homo sapiens_hsa005110.39971105
142Graft-versus-host disease_Homo sapiens_hsa053320.39648354
143Influenza A_Homo sapiens_hsa051640.39422347
144Wnt signaling pathway_Homo sapiens_hsa043100.38814075
145Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.38721011
146Vibrio cholerae infection_Homo sapiens_hsa051100.38172316
147Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.37384403
148DNA replication_Homo sapiens_hsa030300.36522585
149mRNA surveillance pathway_Homo sapiens_hsa030150.34876479
150Butanoate metabolism_Homo sapiens_hsa006500.34783045
151Tight junction_Homo sapiens_hsa045300.34093543
152TGF-beta signaling pathway_Homo sapiens_hsa043500.31709084
153Glycerophospholipid metabolism_Homo sapiens_hsa005640.30246176
154Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.27468129
155Hippo signaling pathway_Homo sapiens_hsa043900.27290934
156Steroid biosynthesis_Homo sapiens_hsa001000.26249600
157Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.26008413
158Metabolic pathways_Homo sapiens_hsa011000.21730063
159FoxO signaling pathway_Homo sapiens_hsa040680.20113366

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »