ARMC7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)6.60591520
2negative regulation of cell killing (GO:0031342)5.94117925
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.94117925
4leukocyte aggregation (GO:0070486)5.85432012
5positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.83359167
6negative T cell selection (GO:0043383)5.73345542
7antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.64752884
8antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.64752884
9regulation of B cell receptor signaling pathway (GO:0050855)5.64062692
10negative thymic T cell selection (GO:0045060)5.54065523
11regulation of isotype switching to IgG isotypes (GO:0048302)5.18829760
12antigen processing and presentation of endogenous antigen (GO:0019883)4.98769528
13T cell migration (GO:0072678)4.93603882
14regulation of gamma-delta T cell differentiation (GO:0045586)4.85332461
15positive thymic T cell selection (GO:0045059)4.83186890
16GDP-mannose metabolic process (GO:0019673)4.78469356
17regulation of gamma-delta T cell activation (GO:0046643)4.70483203
18cellular response to interleukin-15 (GO:0071350)4.62485322
19response to interleukin-15 (GO:0070672)4.58290962
20thymic T cell selection (GO:0045061)4.47015836
21neutrophil activation involved in immune response (GO:0002283)4.43227362
22positive T cell selection (GO:0043368)4.40615678
23regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.16915604
24regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.15542047
25T cell receptor signaling pathway (GO:0050852)4.13318606
26antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.12668314
27T cell selection (GO:0045058)4.10323341
28regulation of B cell differentiation (GO:0045577)4.07773719
29interferon-gamma production (GO:0032609)3.99384763
30pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.99353692
31positive regulation of isotype switching (GO:0045830)3.98595981
32positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.96828885
33regulation of T cell receptor signaling pathway (GO:0050856)3.96105261
34lymphocyte costimulation (GO:0031294)3.95229397
35T cell costimulation (GO:0031295)3.92325311
36antigen receptor-mediated signaling pathway (GO:0050851)3.85846211
37deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.84208740
38G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)3.83286341
39regulation of response to interferon-gamma (GO:0060330)3.82008928
40negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.76550355
41regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.75681657
42positive regulation of DNA recombination (GO:0045911)3.71578765
43mast cell activation (GO:0045576)3.70963167
44regulation of T cell tolerance induction (GO:0002664)3.70730163
45adenosine receptor signaling pathway (GO:0001973)3.62785489
46regulation of chromatin binding (GO:0035561)3.62531212
47NIK/NF-kappaB signaling (GO:0038061)3.61694537
48leukocyte cell-cell adhesion (GO:0007159)3.59021448
49modulation by virus of host process (GO:0019054)3.57188599
50response to peptidoglycan (GO:0032494)3.56486316
51Arp2/3 complex-mediated actin nucleation (GO:0034314)3.55155812
52sequestering of actin monomers (GO:0042989)3.55003823
53negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.53774264
54negative regulation of erythrocyte differentiation (GO:0045647)3.50328966
55regulation of isotype switching (GO:0045191)3.50004867
56positive regulation of alpha-beta T cell proliferation (GO:0046641)3.40026649
57base-excision repair, AP site formation (GO:0006285)3.37563908
58positive regulation of immunoglobulin mediated immune response (GO:0002891)3.34940014
59positive regulation of B cell mediated immunity (GO:0002714)3.34940014
60interferon-gamma-mediated signaling pathway (GO:0060333)3.34596879
61pentose metabolic process (GO:0019321)3.34320545
62negative regulation of nitric oxide biosynthetic process (GO:0045019)3.34121243
63pyrimidine nucleotide catabolic process (GO:0006244)3.32478886
64regulation of mast cell degranulation (GO:0043304)3.31680583
65B cell receptor signaling pathway (GO:0050853)3.31424979
66negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.31111662
67regulation of alpha-beta T cell proliferation (GO:0046640)3.29693106
68activated T cell proliferation (GO:0050798)3.29225394
69immunoglobulin mediated immune response (GO:0016064)3.28854568
70negative regulation of T cell receptor signaling pathway (GO:0050860)3.26761736
71regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.25228551
72regulation of natural killer cell mediated immunity (GO:0002715)3.25228551
73regulation of immunoglobulin mediated immune response (GO:0002889)3.24186380
74pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.22544569
75regulation of B cell mediated immunity (GO:0002712)3.22284570
76regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.20910934
77regulation of type I interferon-mediated signaling pathway (GO:0060338)3.20285104
78positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.19549183
79negative regulation of phagocytosis (GO:0050765)3.19190305
80response to type I interferon (GO:0034340)3.18481575
81cellular extravasation (GO:0045123)3.17607757
82UV protection (GO:0009650)3.16473946
83cellular response to type I interferon (GO:0071357)3.15740439
84type I interferon signaling pathway (GO:0060337)3.15740439
85G-protein coupled purinergic receptor signaling pathway (GO:0035588)3.14902487
86positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.13391262
87positive regulation of natural killer cell mediated immunity (GO:0002717)3.13391262
88regulation of interleukin-12 biosynthetic process (GO:0045075)3.12483108
89deoxyribonucleotide catabolic process (GO:0009264)3.09236545
90rRNA modification (GO:0000154)3.09093621
91pentose-phosphate shunt (GO:0006098)3.08812072
92positive regulation of tolerance induction (GO:0002645)3.08043532
93positive regulation of granulocyte differentiation (GO:0030854)3.07444041
94response to protozoan (GO:0001562)3.07153456
95positive regulation of interleukin-2 production (GO:0032743)3.05414863
96proline biosynthetic process (GO:0006561)3.04489612
97natural killer cell activation (GO:0030101)3.02865223
98defense response to protozoan (GO:0042832)3.01809464
99regulation of interferon-beta biosynthetic process (GO:0045357)2.98408513
100regulation of tolerance induction (GO:0002643)2.98325468
101regulation of interleukin-2 biosynthetic process (GO:0045076)2.98295085
102purinergic nucleotide receptor signaling pathway (GO:0035590)2.97967530
103respiratory burst (GO:0045730)2.97607012
104positive regulation of humoral immune response (GO:0002922)2.97455177
105positive regulation of macrophage differentiation (GO:0045651)2.96089331
106T cell homeostasis (GO:0043029)2.96007999
107protein insertion into membrane (GO:0051205)2.93749075
108deoxyribose phosphate catabolic process (GO:0046386)2.93292353
109pyrimidine nucleoside salvage (GO:0043097)2.93151542
110pyrimidine-containing compound salvage (GO:0008655)2.93151542
111negative regulation of interleukin-12 production (GO:0032695)2.92929309
112cellular defense response (GO:0006968)2.91653290
113modulation by symbiont of host cellular process (GO:0044068)2.91031565
114positive regulation of B cell differentiation (GO:0045579)2.90912580
115regulation of leukocyte degranulation (GO:0043300)2.90373997
116metallo-sulfur cluster assembly (GO:0031163)2.89857984
117iron-sulfur cluster assembly (GO:0016226)2.89857984
118modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.88292309
119positive regulation by organism of defense response of other organism involved in symbiotic interact2.88292309
120modulation by symbiont of host immune response (GO:0052553)2.88292309
121positive regulation by symbiont of host defense response (GO:0052509)2.88292309
122modulation by symbiont of host defense response (GO:0052031)2.88292309
123modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.88292309
124regulation of myeloid leukocyte mediated immunity (GO:0002886)2.88073034
125JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.87571430
126regulation of mast cell activation involved in immune response (GO:0033006)2.87175101
127lymphocyte migration (GO:0072676)2.86843865
128B cell mediated immunity (GO:0019724)2.85477705
129amino sugar catabolic process (GO:0046348)2.84423434
130leukocyte degranulation (GO:0043299)2.82397093
131regulation of superoxide anion generation (GO:0032928)2.81800612
132T-helper cell differentiation (GO:0042093)2.81566047
133CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.81566047
134T cell differentiation (GO:0030217)2.79828231
135immune response-activating cell surface receptor signaling pathway (GO:0002429)2.79592115
136alpha-beta T cell activation (GO:0046631)2.78935234
137neutrophil activation (GO:0042119)2.78076323
138negative regulation of lymphocyte mediated immunity (GO:0002707)2.77316716
139lymphocyte homeostasis (GO:0002260)2.77305913
140positive regulation of mast cell activation (GO:0033005)2.76583807
141ribosomal small subunit biogenesis (GO:0042274)2.74975342
142mannose metabolic process (GO:0006013)2.74523556
143positive regulation of protein homooligomerization (GO:0032464)2.74126753
144granulocyte activation (GO:0036230)2.73851931
145purinergic receptor signaling pathway (GO:0035587)2.73707997
146rRNA methylation (GO:0031167)2.73025554
147lipoxygenase pathway (GO:0019372)2.72733942
148purine deoxyribonucleotide catabolic process (GO:0009155)2.67428880
149mitochondrial calcium ion transport (GO:0006851)2.65997279
150cellular response to virus (GO:0098586)2.65937875
151response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.63922969
152response to host immune response (GO:0052572)2.63922969
153NADPH regeneration (GO:0006740)2.60557979
1543-UTR-mediated mRNA stabilization (GO:0070935)2.60019648
155myeloid cell activation involved in immune response (GO:0002275)2.58442840
156negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.57665672
157negative regulation of innate immune response (GO:0045824)2.57474266
158N-acetylneuraminate metabolic process (GO:0006054)2.57367979
159detection of bacterium (GO:0016045)2.57194667
160positive regulation of Cdc42 GTPase activity (GO:0043089)2.56856648
161granulocyte differentiation (GO:0030851)2.54187560
162negative regulation of B cell apoptotic process (GO:0002903)2.51237601
163response to muramyl dipeptide (GO:0032495)2.50612893
164tolerance induction (GO:0002507)2.50094262
165detection of other organism (GO:0098543)2.49808962
166regulated secretory pathway (GO:0045055)2.47851764
167nucleotide salvage (GO:0043173)2.47423619
168mitochondrial fusion (GO:0008053)2.46933559
169pinocytosis (GO:0006907)2.46018183
170negative regulation of tumor necrosis factor production (GO:0032720)2.45884545
171transcription from mitochondrial promoter (GO:0006390)2.45112888
172macrophage activation involved in immune response (GO:0002281)2.44220818
173pseudouridine synthesis (GO:0001522)2.42835316
174response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.41286131
175response to host (GO:0075136)2.41286131
176response to host defenses (GO:0052200)2.41286131
177positive regulation of mast cell activation involved in immune response (GO:0033008)2.40816453
178positive regulation of mast cell degranulation (GO:0043306)2.40816453
179regulation of regulated secretory pathway (GO:1903305)2.38319522

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.41748161
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.97082776
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.91901233
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.14158494
5IRF8_21731497_ChIP-ChIP_J774_Mouse4.09639353
6E2F7_22180533_ChIP-Seq_HELA_Human3.99760841
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.58427589
8IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.39340814
9STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.37922247
10* SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.36577834
11STAT4_19710469_ChIP-ChIP_TH1__Mouse3.29184012
12FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.99746727
13MYB_26560356_Chip-Seq_TH2_Human2.87348572
14MYC_22102868_ChIP-Seq_BL_Human2.79755241
15* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.78729158
16RUNX_20019798_ChIP-Seq_JUKART_Human2.76414593
17* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.71812970
18TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.63460680
19NOTCH1_21737748_ChIP-Seq_TLL_Human2.59671639
20IRF8_27001747_Chip-Seq_BMDM_Mouse2.57462414
21* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.55170055
22SPI1_23547873_ChIP-Seq_NB4_Human2.54400875
23SCL_19346495_ChIP-Seq_HPC-7_Human2.49951599
24MYB_26560356_Chip-Seq_TH1_Human2.45191326
25MAF_26560356_Chip-Seq_TH1_Human2.43652672
26MYB_21317192_ChIP-Seq_ERMYB_Mouse2.42879866
27* FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.41654985
28HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.38910213
29* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.35593030
30TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.34512803
31SMAD_19615063_ChIP-ChIP_OVARY_Human2.33845419
32* UTX_26944678_Chip-Seq_JUKART_Human2.27189163
33LXR_22292898_ChIP-Seq_THP-1_Human2.15874696
34VDR_21846776_ChIP-Seq_THP-1_Human2.14839816
35EGR1_19374776_ChIP-ChIP_THP-1_Human2.09575684
36* RUNX1_22412390_ChIP-Seq_EML_Mouse2.05195170
37BP1_19119308_ChIP-ChIP_Hs578T_Human2.03514187
38MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.93839313
39ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.93302946
40XRN2_22483619_ChIP-Seq_HELA_Human1.90573150
41VDR_24763502_ChIP-Seq_THP-1_Human1.87834404
42ELF1_17652178_ChIP-ChIP_JURKAT_Human1.85914436
43CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.83679100
44VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.82467609
45P68_20966046_ChIP-Seq_HELA_Human1.76826172
46BRD4_27068464_Chip-Seq_AML-cells_Mouse1.76481826
47* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.75352813
48GATA3_27048872_Chip-Seq_THYMUS_Human1.75344149
49DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.74493936
50MYC_18358816_ChIP-ChIP_MESCs_Mouse1.71870826
51MAF_26560356_Chip-Seq_TH2_Human1.71077517
52MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.69678247
53TET1_21451524_ChIP-Seq_MESCs_Mouse1.69522955
54SRY_22984422_ChIP-ChIP_TESTIS_Rat1.69026037
55NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.66401642
56E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.64818527
57BCL6_27268052_Chip-Seq_Bcells_Human1.61728669
58THAP11_20581084_ChIP-Seq_MESCs_Mouse1.61595722
59RACK7_27058665_Chip-Seq_MCF-7_Human1.59932143
60CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.59894490
61RARG_19884340_ChIP-ChIP_MEFs_Mouse1.55768862
62BCOR_27268052_Chip-Seq_Bcells_Human1.54178865
63CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.53977242
64SPI1_23127762_ChIP-Seq_K562_Human1.53433900
65MYC_18555785_ChIP-Seq_MESCs_Mouse1.52814427
66TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.52787506
67ELF1_20517297_ChIP-Seq_JURKAT_Human1.52135900
68TCF7_22412390_ChIP-Seq_EML_Mouse1.51168564
69CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.50495127
70GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.50241520
71RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.48874947
72CTCF_27219007_Chip-Seq_ERYTHROID_Human1.48544538
73CIITA_25753668_ChIP-Seq_RAJI_Human1.47166324
74HOXB4_20404135_ChIP-ChIP_EML_Mouse1.44865727
75ETS1_20019798_ChIP-Seq_JURKAT_Human1.44561433
76PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.43372286
77* GABP_19822575_ChIP-Seq_HepG2_Human1.42114498
78SA1_27219007_Chip-Seq_ERYTHROID_Human1.40373424
79PU_27001747_Chip-Seq_BMDM_Mouse1.39245898
80GATA2_22383799_ChIP-Seq_G1ME_Mouse1.38134224
81LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.37918285
82EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.37533528
83DCP1A_22483619_ChIP-Seq_HELA_Human1.36983648
84ERG_20887958_ChIP-Seq_HPC-7_Mouse1.34940853
85* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.34853866
86NCOR1_26117541_ChIP-Seq_K562_Human1.34367136
87RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.31653630
88ZNF263_19887448_ChIP-Seq_K562_Human1.29838907
89STAT6_21828071_ChIP-Seq_BEAS2B_Human1.28519257
90KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.27280392
91CTCF_21964334_Chip-Seq_Bcells_Human1.27211857
92PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.26399960
93GATA3_26560356_Chip-Seq_TH2_Human1.25880417
94YY1_22570637_ChIP-Seq_MALME-3M_Human1.25410469
95PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.25406413
96MYC_19030024_ChIP-ChIP_MESCs_Mouse1.24691852
97FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.24388007
98PHF8_20622854_ChIP-Seq_HELA_Human1.21807989
99NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.20768260
100FOXP3_21729870_ChIP-Seq_TREG_Human1.20150245
101VDR_23849224_ChIP-Seq_CD4+_Human1.20097934
102E2F1_20622854_ChIP-Seq_HELA_Human1.19974396
103BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.19942879
104CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.19580492
105CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.15718811
106* CTCF_26484167_Chip-Seq_Bcells_Mouse1.15558832
107CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.15539160
108Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.15482583
109YY1_21170310_ChIP-Seq_MESCs_Mouse1.14525583
110GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.14087826
111FOXP1_21924763_ChIP-Seq_HESCs_Human1.14055108
112PU.1_20513432_ChIP-Seq_Bcells_Mouse1.13398326
113* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.13111578
114NELFA_20434984_ChIP-Seq_ESCs_Mouse1.12997908
115MYC_19079543_ChIP-ChIP_MESCs_Mouse1.12371959
116NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.12218762
117CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.11877339
118CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.10945577
119KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.10159160
120CTCF_21964334_ChIP-Seq_BJAB-B_Human1.09919157
121KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.08778422
122RARB_24833708_ChIP-Seq_LIVER_Mouse1.08444377
123SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.08346371
124FOXM1_23109430_ChIP-Seq_U2OS_Human1.07671981
125KDM5A_27292631_Chip-Seq_BREAST_Human1.07114417
126* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.06668379
127HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.06568787
128* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.04402745
129GABP_17652178_ChIP-ChIP_JURKAT_Human1.01236051
130CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98852624
131KDM2B_26808549_Chip-Seq_DND41_Human0.97551238
132GATA1_22383799_ChIP-Seq_G1ME_Mouse0.96427541
133PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96039847
134* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.94160478
135ELK3_25401928_ChIP-Seq_HUVEC_Human0.93959345
136TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.91465758
137* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90008812
138PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89643141
139THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.89012403
140SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.86584174
141ELK1_19687146_ChIP-ChIP_HELA_Human0.86245192
142STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.82784700
143GATA1_19941827_ChIP-Seq_MEL_Mouse0.81877961
144TP63_19390658_ChIP-ChIP_HaCaT_Human0.80401192
145VDR_24787735_ChIP-Seq_THP-1_Human0.79579051
146TFEB_21752829_ChIP-Seq_HELA_Human0.77232787
147BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.76603542
148E2F4_17652178_ChIP-ChIP_JURKAT_Human0.76423358
149SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.74443353
150KDM2B_26808549_Chip-Seq_SUP-B15_Human0.73039277
151JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.72576393
152CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.71713011
153* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.69928074

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology4.54832947
2MP0001835_abnormal_antigen_presentation4.05321024
3MP0005671_abnormal_response_to3.71556181
4MP0009785_altered_susceptibility_to3.47679303
5MP0000685_abnormal_immune_system3.12423882
6MP0006082_CNS_inflammation3.08152612
7MP0001800_abnormal_humoral_immune3.07285121
8MP0002420_abnormal_adaptive_immunity2.97553501
9MP0001819_abnormal_immune_cell2.94459272
10MP0005387_immune_system_phenotype2.91958345
11MP0001790_abnormal_immune_system2.91958345
12MP0005000_abnormal_immune_tolerance2.89421573
13MP0005025_abnormal_response_to2.85683698
14MP0003436_decreased_susceptibility_to2.82089298
15MP0008260_abnormal_autophagy2.81979298
16MP0002452_abnormal_antigen_presenting2.81648052
17MP0002723_abnormal_immune_serum2.79395810
18MP0002398_abnormal_bone_marrow2.70699613
19MP0003724_increased_susceptibility_to2.67235071
20MP0005083_abnormal_biliary_tract2.59463144
21MP0003806_abnormal_nucleotide_metabolis2.58057389
22MP0002419_abnormal_innate_immunity2.55015909
23MP0002405_respiratory_system_inflammati2.52145148
24MP0002396_abnormal_hematopoietic_system2.48582794
25MP0000716_abnormal_immune_system2.43224881
26MP0009333_abnormal_splenocyte_physiolog2.41676209
27MP0002148_abnormal_hypersensitivity_rea2.39153885
28MP0000689_abnormal_spleen_morphology2.18870949
29MP0005464_abnormal_platelet_physiology2.14694782
30MP0000703_abnormal_thymus_morphology2.13634323
31MP0002722_abnormal_immune_system2.12841608
32MP0004510_myositis2.10501823
33MP0002429_abnormal_blood_cell1.99914232
34MP0004808_abnormal_hematopoietic_stem1.98839073
35MP0010155_abnormal_intestine_physiology1.96001551
36MP0002166_altered_tumor_susceptibility1.93163912
37MP0004947_skin_inflammation1.91589327
38MP0003303_peritoneal_inflammation1.88262181
39MP0009840_abnormal_foam_cell1.86589288
40MP0002132_abnormal_respiratory_system1.85900742
41MP0002933_joint_inflammation1.84572964
42MP0005310_abnormal_salivary_gland1.83846215
43MP0000858_altered_metastatic_potential1.83556323
44MP0001851_eye_inflammation1.81706635
45MP0001845_abnormal_inflammatory_respons1.80897422
46MP0001873_stomach_inflammation1.79395188
47MP0002006_tumorigenesis1.70685816
48MP0003866_abnormal_defecation1.59359325
49MP0005501_abnormal_skin_physiology1.54716499
50MP0001533_abnormal_skeleton_physiology1.51449241
51MP0001853_heart_inflammation1.45327375
52MP0001545_abnormal_hematopoietic_system1.39361977
53MP0005397_hematopoietic_system_phenotyp1.39361977
54MP0006036_abnormal_mitochondrial_physio1.39241452
55MP0003448_altered_tumor_morphology1.38482554
56MP0008469_abnormal_protein_level1.36795510
57MP0006035_abnormal_mitochondrial_morpho1.34156923
58MP0000490_abnormal_crypts_of1.33067857
59MP0005075_abnormal_melanosome_morpholog1.27597164
60MP0000465_gastrointestinal_hemorrhage1.26943055
61MP0004957_abnormal_blastocyst_morpholog1.23747711
62MP0009278_abnormal_bone_marrow1.23288311
63MP0001986_abnormal_taste_sensitivity1.20917721
64MP0000015_abnormal_ear_pigmentation1.18976193
65MP0009764_decreased_sensitivity_to1.15985579
66MP0008004_abnormal_stomach_pH1.15956347
67MP0002019_abnormal_tumor_incidence1.13080776
68MP0000678_abnormal_parathyroid_gland1.12240257
69MP0005174_abnormal_tail_pigmentation1.10103666
70MP0008058_abnormal_DNA_repair1.02734484
71MP0005058_abnormal_lysosome_morphology1.01469728
72MP0000358_abnormal_cell_content/0.98514216
73MP0002998_abnormal_bone_remodeling0.98402847
74MP0005084_abnormal_gallbladder_morpholo0.97631686
75MP0005171_absent_coat_pigmentation0.96431502
76MP0008007_abnormal_cellular_replicative0.95724381
77MP0008932_abnormal_embryonic_tissue0.93460658
78MP0003453_abnormal_keratinocyte_physiol0.92765977
79MP0004381_abnormal_hair_follicle0.89871411
80MP0000750_abnormal_muscle_regeneration0.89799087
81MP0001849_ear_inflammation0.89654517
82MP0002796_impaired_skin_barrier0.86914064
83MP0003075_altered_response_to0.85974959
84MP0003279_aneurysm0.84266578
85MP0005584_abnormal_enzyme/coenzyme_acti0.83455416
86MP0008874_decreased_physiological_sensi0.83241567
87MP0003300_gastrointestinal_ulcer0.82714978
88MP0009931_abnormal_skin_appearance0.81122467
89MP0004185_abnormal_adipocyte_glucose0.80581160
90MP0003183_abnormal_peptide_metabolism0.80299211
91MP0005076_abnormal_cell_differentiation0.79959772
92MP0009765_abnormal_xenobiotic_induced0.79736176
93MP0003111_abnormal_nucleus_morphology0.78694029
94MP0000343_altered_response_to0.78448794
95MP0003077_abnormal_cell_cycle0.75819368
96MP0001730_embryonic_growth_arrest0.75794115
97MP0000350_abnormal_cell_proliferation0.75030160
98MP0001764_abnormal_homeostasis0.74852005
99MP0005360_urolithiasis0.74398603
100MP0003828_pulmonary_edema0.74340295
101MP0005166_decreased_susceptibility_to0.74087726
102MP0005023_abnormal_wound_healing0.72905676
103MP0003693_abnormal_embryo_hatching0.71825069
104MP0009763_increased_sensitivity_to0.71494554
105MP0005451_abnormal_body_composition0.71296743
106MP0002095_abnormal_skin_pigmentation0.70954651
107MP0002138_abnormal_hepatobiliary_system0.70388216
108MP0005390_skeleton_phenotype0.70038850
109MP0008875_abnormal_xenobiotic_pharmacok0.69862786
110MP0003172_abnormal_lysosome_physiology0.65975517
111MP0010094_abnormal_chromosome_stability0.64736229
112MP0000313_abnormal_cell_death0.63526825
113MP0003795_abnormal_bone_structure0.62801109
114MP0010307_abnormal_tumor_latency0.60553607
115MP0001348_abnormal_lacrimal_gland0.59274805
116MP0003786_premature_aging0.58859994
117MP0002277_abnormal_respiratory_mucosa0.57553999
118MP0000371_diluted_coat_color0.55634065
119MP0003656_abnormal_erythrocyte_physiolo0.51079845
120MP0001191_abnormal_skin_condition0.47124675
121MP0002136_abnormal_kidney_physiology0.46521979
122MP0000249_abnormal_blood_vessel0.45877869
123MP0001663_abnormal_digestive_system0.45857208
124MP0008873_increased_physiological_sensi0.45483718
125MP0002928_abnormal_bile_duct0.44682225
126MP0006292_abnormal_olfactory_placode0.42176471
127MP0000477_abnormal_intestine_morphology0.41935623
128MP0003191_abnormal_cellular_cholesterol0.40711176
129MP0003186_abnormal_redox_activity0.39025557

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)5.05472176
2Recurrent abscess formation (HP:0002722)4.99844191
3Abnormality of T cell number (HP:0011839)4.95922315
4Elevated erythrocyte sedimentation rate (HP:0003565)4.85076809
5Eczematoid dermatitis (HP:0000976)4.84605831
6Abnormality of T cells (HP:0002843)4.55572593
7IgM deficiency (HP:0002850)4.48354646
8Abnormal delayed hypersensitivity skin test (HP:0002963)4.23994109
9Recurrent fungal infections (HP:0002841)4.12154062
10Myositis (HP:0100614)3.88620300
11Recurrent bacterial skin infections (HP:0005406)3.87255509
12Stomatitis (HP:0010280)3.87224540
13Recurrent viral infections (HP:0004429)3.85205012
14Panhypogammaglobulinemia (HP:0003139)3.84806413
15Chronic mucocutaneous candidiasis (HP:0002728)3.73607744
16Recurrent cutaneous fungal infections (HP:0011370)3.73607744
17Recurrent bronchitis (HP:0002837)3.73139172
18Chronic otitis media (HP:0000389)3.70992934
19IgG deficiency (HP:0004315)3.66111949
20Severe combined immunodeficiency (HP:0004430)3.59269079
21Chronic obstructive pulmonary disease (HP:0006510)3.57060575
22Obstructive lung disease (HP:0006536)3.57060575
23Testicular atrophy (HP:0000029)3.52991370
24Combined immunodeficiency (HP:0005387)3.52760381
25Autoimmune thrombocytopenia (HP:0001973)3.45768864
26Lymphopenia (HP:0001888)3.44039493
27Nasal polyposis (HP:0100582)3.40687330
28Mediastinal lymphadenopathy (HP:0100721)3.37537458
29Recurrent skin infections (HP:0001581)3.32071434
30Meningitis (HP:0001287)3.28789185
31Abnormality of cells of the lymphoid lineage (HP:0012140)3.28413827
32Increased IgM level (HP:0003496)3.27697125
33Ragged-red muscle fibers (HP:0003200)3.23048542
34Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.21964219
35Purpura (HP:0000979)3.21886489
36Abnormality of T cell physiology (HP:0011840)3.20523479
37Recurrent gram-negative bacterial infections (HP:0005420)3.17068860
38Thrombocytosis (HP:0001894)3.15495649
39Leukocytosis (HP:0001974)3.15090102
40Epistaxis (HP:0000421)3.10599281
41Thoracic kyphosis (HP:0002942)3.05481512
42Prolonged bleeding time (HP:0003010)3.04258664
43Vaginal fistula (HP:0004320)3.03592562
44Thyroiditis (HP:0100646)2.94084723
45Chronic diarrhea (HP:0002028)2.90779680
46Gastrointestinal infarctions (HP:0005244)2.90209800
47Abnormality of eosinophils (HP:0001879)2.87527117
48Rectovaginal fistula (HP:0000143)2.86713099
49Rectal fistula (HP:0100590)2.86713099
50Pustule (HP:0200039)2.86530129
51Vasculitis (HP:0002633)2.86358679
52Vacuolated lymphocytes (HP:0001922)2.85758224
53Abnormality of the nasal mucosa (HP:0000433)2.84336489
54Encephalitis (HP:0002383)2.78477571
55Agammaglobulinemia (HP:0004432)2.78143890
56Abnormality of macrophages (HP:0004311)2.75712675
57Orchitis (HP:0100796)2.73943981
58Eosinophilia (HP:0001880)2.73833260
59Intestinal fistula (HP:0100819)2.72569996
60Retrobulbar optic neuritis (HP:0100654)2.67489120
61Optic neuritis (HP:0100653)2.67489120
62Gingivitis (HP:0000230)2.67264347
63Autoimmune hemolytic anemia (HP:0001890)2.63693908
64Inflammation of the large intestine (HP:0002037)2.63054611
65Renal Fanconi syndrome (HP:0001994)2.61139432
66Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.60501161
67Annular pancreas (HP:0001734)2.60092262
68Abnormality of the heme biosynthetic pathway (HP:0010472)2.57991383
69Dyschromatopsia (HP:0007641)2.57787773
70Hepatosplenomegaly (HP:0001433)2.57105859
71Increased muscle lipid content (HP:0009058)2.55884157
72Increased intramyocellular lipid droplets (HP:0012240)2.54030544
73Joint swelling (HP:0001386)2.53051191
74Progressive muscle weakness (HP:0003323)2.49663453
75Increased serum ferritin (HP:0003281)2.49516595
76Progressive external ophthalmoplegia (HP:0000590)2.47791108
77Gingival bleeding (HP:0000225)2.46494718
78Entropion (HP:0000621)2.45347909
79Gastrointestinal inflammation (HP:0004386)2.44690848
80Hemorrhage of the eye (HP:0011885)2.44040190
81Hemoptysis (HP:0002105)2.43458052
82Impaired platelet aggregation (HP:0003540)2.42681589
83Abnormal platelet function (HP:0011869)2.42681589
84Hypertensive crisis (HP:0100735)2.42159706
85Chest pain (HP:0100749)2.42159357
86Petechiae (HP:0000967)2.40747754
87Rough bone trabeculation (HP:0100670)2.39568969
88Arterial thrombosis (HP:0004420)2.39094658
89Abnormality of the prostate (HP:0008775)2.38517442
90Recurrent sinusitis (HP:0011108)2.37845241
91Hypergammaglobulinemia (HP:0010702)2.37137051
92Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.36658820
93Decreased activity of mitochondrial respiratory chain (HP:0008972)2.36658820
94Granulocytopenia (HP:0001913)2.36350694
95Joint hemorrhage (HP:0005261)2.36282720
96Spontaneous hematomas (HP:0007420)2.34389080
97Aplasia/Hypoplasia of the sacrum (HP:0008517)2.31665554
98Squamous cell carcinoma (HP:0002860)2.28182071
99Thin bony cortex (HP:0002753)2.28140109
100Loss of speech (HP:0002371)2.24886602
101Lymphoma (HP:0002665)2.23851941
102Abnormal trabecular bone morphology (HP:0100671)2.23502515
103Pulmonary infiltrates (HP:0002113)2.22834846
104Myopathic facies (HP:0002058)2.22540760
105Cellulitis (HP:0100658)2.20762600
106Respiratory difficulties (HP:0002880)2.20136059
107Amaurosis fugax (HP:0100576)2.19800062
108Dysostosis multiplex (HP:0000943)2.17406375
109Urticaria (HP:0001025)2.15318697
110Increased IgE level (HP:0003212)2.11635441
111Microretrognathia (HP:0000308)2.10279882
112Reduced antithrombin III activity (HP:0001976)2.09931980
113Poikiloderma (HP:0001029)2.07554986
114Abnormality of iron homeostasis (HP:0011031)2.06434240
115Abnormality of the thoracic spine (HP:0100711)2.05655724
116Menorrhagia (HP:0000132)2.03994929
117Chronic sinusitis (HP:0011109)2.03267689
118Viral hepatitis (HP:0006562)2.01724470
119Periodontitis (HP:0000704)2.00766767
120Bronchitis (HP:0012387)1.99915677
121Mesangial abnormality (HP:0001966)1.99407412
122Hypoplasia of the thymus (HP:0000778)1.98297795
123Abnormality of the fingertips (HP:0001211)1.98048667
124Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.96918450
125Hypochromic anemia (HP:0001931)1.96855503
126Albinism (HP:0001022)1.95799411
127Anorexia (HP:0002039)1.94361308
128Abnormal platelet volume (HP:0011876)1.93400323
129Keratoconjunctivitis sicca (HP:0001097)1.92662549
130Male infertility (HP:0003251)1.92545049
131Easy fatigability (HP:0003388)1.91720525
132Skin ulcer (HP:0200042)1.90142355
133Increased mean platelet volume (HP:0011877)1.89750952
134B lymphocytopenia (HP:0010976)1.89662959
135Abnormality of B cell number (HP:0010975)1.89662959
136Abnormality of mucopolysaccharide metabolism (HP:0011020)1.88107695
137Abnormality of polysaccharide metabolism (HP:0011012)1.88107695
138Abnormality of glycosaminoglycan metabolism (HP:0004371)1.88107695
139Abnormal hair whorl (HP:0010721)1.87933023
140Colitis (HP:0002583)1.87576187
141Abnormality of the costochondral junction (HP:0000919)1.87209598
142Abnormality of the intrinsic pathway (HP:0010989)1.86684607
143Acrocyanosis (HP:0001063)1.86539780
144Glomerulopathy (HP:0100820)1.85344465
145Premature graying of hair (HP:0002216)1.85329326
146Increased cerebral lipofuscin (HP:0011813)1.85229388
147Cholelithiasis (HP:0001081)1.84834359
148Abnormality of DNA repair (HP:0003254)1.84657502
149Abnormality of lateral ventricle (HP:0030047)1.83952140
150Basal ganglia calcification (HP:0002135)1.83241210
151Breast hypoplasia (HP:0003187)1.80773011
152IgA deficiency (HP:0002720)1.80490001
153Microvesicular hepatic steatosis (HP:0001414)1.80248149
154Rib fusion (HP:0000902)1.79743456
155Mucopolysacchariduria (HP:0008155)1.79325719
156Urinary glycosaminoglycan excretion (HP:0003541)1.79325719
157Ulnar bowing (HP:0003031)1.78293904
158Muscle fiber atrophy (HP:0100295)1.78132839
159Type 2 muscle fiber atrophy (HP:0003554)1.78128601
160Increased hepatocellular lipid droplets (HP:0006565)1.76454703
161Abnormal gallbladder physiology (HP:0012438)1.76198582
162Cholecystitis (HP:0001082)1.76198582
163Aplasia/Hypoplasia of the thymus (HP:0010515)1.73641116

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK5.19016570
2MAP4K15.00735782
3JAK33.10924866
4ZAP702.96876669
5TAOK22.92668240
6PRPF4B2.69636968
7SMG12.69079524
8IKBKE2.52523541
9MAP3K112.49424020
10TYK22.37919881
11STK102.37021402
12KIT2.33579391
13MAP3K142.29780122
14ITK2.27919315
15IRAK42.20843757
16BLK2.05104450
17TEC2.01839205
18BTK1.91500760
19MAP3K121.89761325
20TRIB31.85205486
21LCK1.84069292
22MST41.83646221
23CLK11.81840061
24TBK11.79278383
25GRK61.69950647
26VRK21.69142136
27SYK1.68058431
28CSF1R1.58045443
29HCK1.55011221
30NME21.54126472
31JAK11.52528951
32MARK31.51195537
33SIK31.50893345
34IKBKB1.48793466
35SIK11.44746314
36CSK1.41487287
37MAP2K61.40351597
38NLK1.40061803
39TESK11.39768495
40NEK91.37457535
41FES1.33533598
42EPHA31.33485953
43FGFR41.32731363
44BMX1.29599667
45TESK21.27108317
46MAP3K31.26615612
47EPHA21.24263679
48BUB11.18351476
49PRKD21.16540581
50AURKA1.13118180
51KDR1.13009406
52ARAF1.11405959
53MAP3K131.07331515
54STK161.06803349
55ICK1.06743301
56MAPK151.04272482
57PIM11.04113271
58LYN1.03502208
59ACVR1B0.99665794
60BCKDK0.99173492
61TAOK30.97899204
62TGFBR20.94452122
63MAP3K50.94264522
64IRAK30.92701792
65MAP3K10.91534059
66PRKCQ0.89910516
67FGFR30.88104498
68DYRK1B0.84950701
69VRK10.83512552
70MATK0.81432628
71PAK10.81322252
72PDPK10.81080936
73PRKCH0.79722948
74CHUK0.78677659
75RPS6KA40.78387395
76FLT30.74439948
77MAP3K60.73888409
78CDK40.71331634
79TLK10.71205756
80MAP2K30.70934311
81TGFBR10.70437948
82MAP3K80.69607353
83MST1R0.68403607
84LRRK20.67883264
85RPS6KA60.67825329
86PAK40.66624876
87MARK20.65762001
88MAP2K20.65731475
89DAPK10.65525728
90TNK20.63458732
91JAK20.58406592
92MAP2K40.57674236
93ERN10.57069400
94STK40.56190172
95PIM20.55439680
96BMPR1B0.54519534
97CDK70.54309396
98SIK20.53695248
99ABL20.53422520
100SCYL20.51995958
101PBK0.51334627
102MAPK120.49969594
103ADRBK20.48934586
104PDK20.47840328
105SRPK10.47096085
106BRSK20.46781678
107RAF10.46758446
108ALK0.46307943
109CDK120.44858358
110RIPK40.44424054
111PDK10.43726454
112TAOK10.41867231
113RPS6KL10.41835771
114RPS6KC10.41835771
115PTK60.41147090
116MAP2K70.41026328
117IRAK20.39873545
118SGK20.39726644
119SGK30.39546870
120CHEK20.37659800
121DAPK30.37520133
122PRKG20.37401063
123PRKD10.36933814
124KSR20.36229697
125DMPK0.35853377
126CCNB10.35169233
127PRKCD0.34614757
128MAP3K100.33222777
129CDK190.33022860
130MAPK30.32984893
131MAPK40.32089955
132ABL10.30051135
133CDC70.28560356
134WEE10.28553697
135IGF1R0.27747472
136NUAK10.26770085
137FGR0.26653993
138STK240.25210744
139IRAK10.23302282
140HIPK20.23130088
141ATR0.23041166
142EIF2AK10.22982227
143EPHB10.22943798
144MAPK110.22263351
145MAPKAPK20.22135657
146FYN0.21921985

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.31141059
2Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046503.08544912
3Leishmaniasis_Homo sapiens_hsa051402.78192706
4Graft-versus-host disease_Homo sapiens_hsa053322.72797427
5T cell receptor signaling pathway_Homo sapiens_hsa046602.64056706
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.59005135
7Antigen processing and presentation_Homo sapiens_hsa046122.58225183
8Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.52014934
9Measles_Homo sapiens_hsa051622.50159099
10NF-kappa B signaling pathway_Homo sapiens_hsa040642.49263923
11Fructose and mannose metabolism_Homo sapiens_hsa000512.22148179
12Allograft rejection_Homo sapiens_hsa053302.13612683
13Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.13115961
14Osteoclast differentiation_Homo sapiens_hsa043802.09610069
15Hematopoietic cell lineage_Homo sapiens_hsa046402.07822954
16Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.04922699
17B cell receptor signaling pathway_Homo sapiens_hsa046621.92240666
18Herpes simplex infection_Homo sapiens_hsa051681.75136634
19RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.68533309
20Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.63225540
21Toll-like receptor signaling pathway_Homo sapiens_hsa046201.60745750
22Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.58404948
23Pentose phosphate pathway_Homo sapiens_hsa000301.56185981
24TNF signaling pathway_Homo sapiens_hsa046681.49274512
25Jak-STAT signaling pathway_Homo sapiens_hsa046301.49233004
26Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.45870363
27NOD-like receptor signaling pathway_Homo sapiens_hsa046211.44880320
28Staphylococcus aureus infection_Homo sapiens_hsa051501.42223180
29Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.37982002
30Viral myocarditis_Homo sapiens_hsa054161.37935439
31DNA replication_Homo sapiens_hsa030301.36618282
32Shigellosis_Homo sapiens_hsa051311.35270915
33Influenza A_Homo sapiens_hsa051641.33913399
34Apoptosis_Homo sapiens_hsa042101.29180303
35Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.29114353
36Chemokine signaling pathway_Homo sapiens_hsa040621.28164723
37Toxoplasmosis_Homo sapiens_hsa051451.26358594
38Base excision repair_Homo sapiens_hsa034101.25494307
39Autoimmune thyroid disease_Homo sapiens_hsa053201.25429261
40Legionellosis_Homo sapiens_hsa051341.25191880
41Malaria_Homo sapiens_hsa051441.24832900
42Leukocyte transendothelial migration_Homo sapiens_hsa046701.24792513
43Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.23051750
44Biosynthesis of amino acids_Homo sapiens_hsa012301.23000873
45Hepatitis B_Homo sapiens_hsa051611.21878589
46Acute myeloid leukemia_Homo sapiens_hsa052211.18753444
47Tuberculosis_Homo sapiens_hsa051521.18743370
48Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.17716016
49Galactose metabolism_Homo sapiens_hsa000521.11634512
50Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.06804553
51Nucleotide excision repair_Homo sapiens_hsa034201.06122591
52Pertussis_Homo sapiens_hsa051331.04244732
53Bladder cancer_Homo sapiens_hsa052191.03661227
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.02176704
55Epstein-Barr virus infection_Homo sapiens_hsa051691.00691313
56Asthma_Homo sapiens_hsa053100.99839099
57Other glycan degradation_Homo sapiens_hsa005110.98994198
582-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.97761547
59Type I diabetes mellitus_Homo sapiens_hsa049400.96118488
60Salmonella infection_Homo sapiens_hsa051320.91387259
61HTLV-I infection_Homo sapiens_hsa051660.86788180
62Rheumatoid arthritis_Homo sapiens_hsa053230.85143151
63p53 signaling pathway_Homo sapiens_hsa041150.83268504
64RNA polymerase_Homo sapiens_hsa030200.81407868
65Pancreatic cancer_Homo sapiens_hsa052120.80421894
66Platelet activation_Homo sapiens_hsa046110.79109010
67Lysosome_Homo sapiens_hsa041420.78347220
68Mismatch repair_Homo sapiens_hsa034300.77867660
69Hepatitis C_Homo sapiens_hsa051600.77062072
70Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.77027739
71Spliceosome_Homo sapiens_hsa030400.74671180
72Collecting duct acid secretion_Homo sapiens_hsa049660.74653288
73Glutathione metabolism_Homo sapiens_hsa004800.73820962
74Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.73307761
75Homologous recombination_Homo sapiens_hsa034400.70610436
76Drug metabolism - other enzymes_Homo sapiens_hsa009830.70055678
77Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.69849027
78Prolactin signaling pathway_Homo sapiens_hsa049170.69199827
79Non-homologous end-joining_Homo sapiens_hsa034500.68443941
80Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.68249890
81Viral carcinogenesis_Homo sapiens_hsa052030.68054768
82Pyrimidine metabolism_Homo sapiens_hsa002400.67990936
83Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.65189172
84Folate biosynthesis_Homo sapiens_hsa007900.64735801
85Proteasome_Homo sapiens_hsa030500.62776210
86Sulfur metabolism_Homo sapiens_hsa009200.62661033
87VEGF signaling pathway_Homo sapiens_hsa043700.62334521
88Transcriptional misregulation in cancer_Homo sapiens_hsa052020.61808635
89Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61686317
90Basal transcription factors_Homo sapiens_hsa030220.61615153
91Vibrio cholerae infection_Homo sapiens_hsa051100.61336101
92Central carbon metabolism in cancer_Homo sapiens_hsa052300.61148933
93Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.61061593
94Non-small cell lung cancer_Homo sapiens_hsa052230.60375262
95Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57835198
96AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.57061718
97Chronic myeloid leukemia_Homo sapiens_hsa052200.56836869
98Regulation of autophagy_Homo sapiens_hsa041400.56112942
99Neurotrophin signaling pathway_Homo sapiens_hsa047220.55954398
100N-Glycan biosynthesis_Homo sapiens_hsa005100.55836007
101Ribosome_Homo sapiens_hsa030100.54693722
102Colorectal cancer_Homo sapiens_hsa052100.54397954
103SNARE interactions in vesicular transport_Homo sapiens_hsa041300.53691616
104RNA degradation_Homo sapiens_hsa030180.53639121
105Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.53069197
106Cell cycle_Homo sapiens_hsa041100.52732691
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52434577
108Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.51264321
109Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50677013
110Carbon metabolism_Homo sapiens_hsa012000.50002242
111Notch signaling pathway_Homo sapiens_hsa043300.49876638
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.49591359
113Phagosome_Homo sapiens_hsa041450.49131827
114Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.48347135
115Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.47086812
116Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.46418574
117Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.45477880
118Parkinsons disease_Homo sapiens_hsa050120.45459723
119Thyroid cancer_Homo sapiens_hsa052160.44667617
120MAPK signaling pathway_Homo sapiens_hsa040100.44511565
121FoxO signaling pathway_Homo sapiens_hsa040680.44352528
122Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.40867012
123Glycosaminoglycan degradation_Homo sapiens_hsa005310.35854744
124Sphingolipid signaling pathway_Homo sapiens_hsa040710.35595199
125African trypanosomiasis_Homo sapiens_hsa051430.34565354
126Fanconi anemia pathway_Homo sapiens_hsa034600.33121480
127Sulfur relay system_Homo sapiens_hsa041220.27172493
128Rap1 signaling pathway_Homo sapiens_hsa040150.25215419
129Endocytosis_Homo sapiens_hsa041440.23499573

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