ARMCX5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)4.91319181
2synaptic vesicle docking involved in exocytosis (GO:0016081)4.70788778
3neuron cell-cell adhesion (GO:0007158)4.65449523
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.58043335
5presynaptic membrane assembly (GO:0097105)4.50172076
6regulation of short-term neuronal synaptic plasticity (GO:0048172)4.44729773
7neuronal action potential propagation (GO:0019227)4.35356517
8regulation of synaptic vesicle exocytosis (GO:2000300)4.32998215
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.23977860
10vocalization behavior (GO:0071625)4.22858660
11protein localization to synapse (GO:0035418)4.14545079
12glutamate secretion (GO:0014047)4.09653836
13regulation of synaptic vesicle transport (GO:1902803)4.03962854
14regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.03095911
15gamma-aminobutyric acid signaling pathway (GO:0007214)3.95574969
16presynaptic membrane organization (GO:0097090)3.89296948
17postsynaptic membrane organization (GO:0001941)3.82957716
18pyrimidine nucleobase catabolic process (GO:0006208)3.76043296
19protein-cofactor linkage (GO:0018065)3.72222406
20protein complex biogenesis (GO:0070271)3.68271926
21positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.66218770
22regulation of glutamate receptor signaling pathway (GO:1900449)3.65935291
23DNA double-strand break processing (GO:0000729)3.62130820
24proteasome assembly (GO:0043248)3.57297210
25regulation of vesicle fusion (GO:0031338)3.54237006
26mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.51600603
27mitochondrial respiratory chain complex assembly (GO:0033108)3.49064988
28response to histamine (GO:0034776)3.49037611
29neuron-neuron synaptic transmission (GO:0007270)3.48707839
30cullin deneddylation (GO:0010388)3.48233896
31positive regulation of neurotransmitter secretion (GO:0001956)3.47774210
32regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.47712821
33glutamate receptor signaling pathway (GO:0007215)3.47122494
34synaptic transmission, glutamatergic (GO:0035249)3.44324165
35positive regulation of neurotransmitter transport (GO:0051590)3.44042222
36ionotropic glutamate receptor signaling pathway (GO:0035235)3.38962116
37mitochondrial respiratory chain complex I assembly (GO:0032981)3.37270149
38NADH dehydrogenase complex assembly (GO:0010257)3.37270149
39mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.37270149
40establishment of protein localization to mitochondrial membrane (GO:0090151)3.36462555
41synaptic vesicle maturation (GO:0016188)3.34620840
42DNA damage response, detection of DNA damage (GO:0042769)3.33328330
43histone H2A acetylation (GO:0043968)3.31901331
44regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.30592532
45regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.30592532
46neurotransmitter secretion (GO:0007269)3.29903769
47negative regulation of hormone biosynthetic process (GO:0032353)3.27867344
48negative regulation of hormone metabolic process (GO:0032351)3.27867344
49regulation of meiosis I (GO:0060631)3.24907371
50long-term synaptic potentiation (GO:0060291)3.21857673
51positive regulation of membrane potential (GO:0045838)3.20727987
52synaptic vesicle endocytosis (GO:0048488)3.20383752
53regulation of excitatory postsynaptic membrane potential (GO:0060079)3.15518187
54respiratory chain complex IV assembly (GO:0008535)3.14533411
55regulation of neurotransmitter secretion (GO:0046928)3.14518626
56protein deneddylation (GO:0000338)3.11716372
57G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.11583321
58negative regulation of synaptic transmission, GABAergic (GO:0032229)3.09996483
59behavioral response to ethanol (GO:0048149)3.07902080
60nucleobase catabolic process (GO:0046113)3.07844296
61negative regulation of dendrite morphogenesis (GO:0050774)3.06440164
62positive regulation of vesicle fusion (GO:0031340)3.05948951
63negative regulation of DNA recombination (GO:0045910)3.05495299
64regulation of long-term neuronal synaptic plasticity (GO:0048169)3.04493072
65cytochrome complex assembly (GO:0017004)3.03376722
66sequestering of actin monomers (GO:0042989)3.02944014
67neurotransmitter-gated ion channel clustering (GO:0072578)3.02282615
68regulation of postsynaptic membrane potential (GO:0060078)3.01227701
69behavioral response to cocaine (GO:0048148)2.99415313
70resolution of meiotic recombination intermediates (GO:0000712)2.95783841
71chaperone-mediated protein transport (GO:0072321)2.95224998
72regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.94260480
73regulation of mitotic spindle checkpoint (GO:1903504)2.94260480
74regulation of neuronal synaptic plasticity (GO:0048168)2.92552353
75nonmotile primary cilium assembly (GO:0035058)2.92108874
76regulation of neurotransmitter transport (GO:0051588)2.91361090
77positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.90180292
78establishment of synaptic vesicle localization (GO:0097480)2.89307092
79synaptic vesicle transport (GO:0048489)2.89307092
80positive regulation of meiosis (GO:0045836)2.89188767
81neuron recognition (GO:0008038)2.89147035
82protein neddylation (GO:0045116)2.89044267
83regulation of helicase activity (GO:0051095)2.88914356
84startle response (GO:0001964)2.87722055
85regulation of meiosis (GO:0040020)2.87430488
86positive regulation of mitochondrial fission (GO:0090141)2.86112916
87mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.84628529
88regulation of synaptic transmission, glutamatergic (GO:0051966)2.83908240
89somatic diversification of immune receptors via somatic mutation (GO:0002566)2.82737985
90somatic hypermutation of immunoglobulin genes (GO:0016446)2.82737985
91establishment of integrated proviral latency (GO:0075713)2.82530784
92detection of calcium ion (GO:0005513)2.81597530
93neural tube formation (GO:0001841)2.80972967
94ATP synthesis coupled proton transport (GO:0015986)2.80499292
95energy coupled proton transport, down electrochemical gradient (GO:0015985)2.80499292
96replication fork processing (GO:0031297)2.78454132
97cilium morphogenesis (GO:0060271)2.77242666
98neurotransmitter transport (GO:0006836)2.74913118
99negative regulation of neurotransmitter transport (GO:0051589)2.74542125
100ubiquinone metabolic process (GO:0006743)2.74518067
101epithelial cilium movement (GO:0003351)2.73396562
102dopamine transport (GO:0015872)2.72725570
103lysine catabolic process (GO:0006554)2.72499975
104lysine metabolic process (GO:0006553)2.72499975
105regulation of synaptic plasticity (GO:0048167)2.71782917
106positive regulation of synapse maturation (GO:0090129)2.71155054
107locomotory exploration behavior (GO:0035641)2.69258901
108negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.68966221
109negative regulation of translation, ncRNA-mediated (GO:0040033)2.68966221
110regulation of translation, ncRNA-mediated (GO:0045974)2.68966221
111striatum development (GO:0021756)2.68571875
112transferrin transport (GO:0033572)2.67318557
113positive regulation of meiotic cell cycle (GO:0051446)2.66894382
114establishment of vesicle localization (GO:0051650)2.66841507
115regulation of hexokinase activity (GO:1903299)2.65395295
116regulation of glucokinase activity (GO:0033131)2.65395295
117negative regulation of DNA-dependent DNA replication (GO:2000104)2.65194740
118regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.63126271
119nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.62071787
120axonal fasciculation (GO:0007413)2.61888064
121inner mitochondrial membrane organization (GO:0007007)2.60725832
122exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.59723298
123exploration behavior (GO:0035640)2.59259817
124fear response (GO:0042596)2.58910887
125synapsis (GO:0007129)2.57609295
126regulation of glutamate secretion (GO:0014048)2.56774795
127negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.56549063
128ubiquinone biosynthetic process (GO:0006744)2.56334904
129maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.55413210
130intraspecies interaction between organisms (GO:0051703)2.55126080
131social behavior (GO:0035176)2.55126080
132epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.55018579
133regulation of meiotic cell cycle (GO:0051445)2.54986107
134response to pheromone (GO:0019236)2.54778974
135DNA integration (GO:0015074)2.53775455
136piRNA metabolic process (GO:0034587)2.53303020
137intraciliary transport (GO:0042073)2.53050265
138cerebellar Purkinje cell differentiation (GO:0021702)2.52537113
139regulation of neurotransmitter uptake (GO:0051580)2.52523171
140regulation of cAMP-dependent protein kinase activity (GO:2000479)2.52121078
141behavioral fear response (GO:0001662)2.52003896
142behavioral defense response (GO:0002209)2.52003896
143G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.50496316
144respiratory electron transport chain (GO:0022904)2.50413998
145retinal ganglion cell axon guidance (GO:0031290)2.50331174
146positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.50059931
147mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.50026006
148positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.50026006
149regulation of neurotransmitter levels (GO:0001505)2.49632637
150regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.49507019
151positive regulation of synapse assembly (GO:0051965)2.49111297
152spliceosomal snRNP assembly (GO:0000387)2.48718734
153negative regulation of dendrite development (GO:2000171)2.48646323
154electron transport chain (GO:0022900)2.47138890
155positive regulation of synaptic transmission (GO:0050806)2.47025252
156membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.46740242
157learning (GO:0007612)2.46080395
158long-term memory (GO:0007616)2.45922391
159membrane depolarization (GO:0051899)2.45847300
160trivalent inorganic cation transport (GO:0072512)2.45745959
161ferric iron transport (GO:0015682)2.45745959
162transmission of nerve impulse (GO:0019226)2.45454741
163regulation of synapse maturation (GO:0090128)2.43358118
164regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.42999736
165positive regulation of protein homodimerization activity (GO:0090073)2.42869073
166vesicle docking involved in exocytosis (GO:0006904)2.42547692
167regulation of mitochondrial translation (GO:0070129)2.41487446
168mitotic metaphase plate congression (GO:0007080)2.40976856
169non-recombinational repair (GO:0000726)2.40380849
170double-strand break repair via nonhomologous end joining (GO:0006303)2.40380849
171L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.39355672
172protein K11-linked deubiquitination (GO:0035871)2.38981838
173regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.38864187
174DNA ligation (GO:0006266)2.37971280
175limb bud formation (GO:0060174)2.35927384
176DNA methylation involved in gamete generation (GO:0043046)2.35157806
177CENP-A containing nucleosome assembly (GO:0034080)2.35099669
178positive regulation of mRNA processing (GO:0050685)2.34257322
179nucleotide-excision repair, DNA gap filling (GO:0006297)2.33892629
180chromatin remodeling at centromere (GO:0031055)2.32911795
181indolalkylamine metabolic process (GO:0006586)2.32519237
182protein K11-linked ubiquitination (GO:0070979)2.32471376
183postreplication repair (GO:0006301)2.32205687
184kidney morphogenesis (GO:0060993)2.31757086
185intra-S DNA damage checkpoint (GO:0031573)2.31183392
186establishment of viral latency (GO:0019043)2.30537203
187metaphase plate congression (GO:0051310)2.29174865
188anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.29098503
189tryptophan metabolic process (GO:0006568)2.29027783
190hindbrain development (GO:0030902)2.27983912
191regulation of acyl-CoA biosynthetic process (GO:0050812)2.26636516
192maturation of 5.8S rRNA (GO:0000460)2.26503877
193regulation of cilium movement (GO:0003352)2.24755514
194negative regulation of ligase activity (GO:0051352)2.24076222
195negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.24076222

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.15320420
2GBX2_23144817_ChIP-Seq_PC3_Human4.27884528
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.54555031
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.24227369
5GABP_17652178_ChIP-ChIP_JURKAT_Human2.99686137
6EST1_17652178_ChIP-ChIP_JURKAT_Human2.86855132
7FUS_26573619_Chip-Seq_HEK293_Human2.71469300
8SMAD_19615063_ChIP-ChIP_OVARY_Human2.69627910
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.69244025
10TAF15_26573619_Chip-Seq_HEK293_Human2.68023594
11POU3F2_20337985_ChIP-ChIP_501MEL_Human2.52546473
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.51252851
13CTBP2_25329375_ChIP-Seq_LNCAP_Human2.42106909
14NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.41757426
15ELK1_19687146_ChIP-ChIP_HELA_Human2.33507876
16HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.30337092
17SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.27447453
18CTBP1_25329375_ChIP-Seq_LNCAP_Human2.21527203
19JARID2_20064375_ChIP-Seq_MESCs_Mouse2.19593460
20REST_21632747_ChIP-Seq_MESCs_Mouse2.13625753
21SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.11995197
22P300_19829295_ChIP-Seq_ESCs_Human2.10108138
23ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.09185288
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.00717104
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.98718012
26CREB1_15753290_ChIP-ChIP_HEK293T_Human1.98167246
27E2F4_17652178_ChIP-ChIP_JURKAT_Human1.94306726
28PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.92769681
29SMAD4_21799915_ChIP-Seq_A2780_Human1.92232645
30GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.89191416
31VDR_23849224_ChIP-Seq_CD4+_Human1.87373843
32CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.85896268
33IGF1R_20145208_ChIP-Seq_DFB_Human1.85525218
34SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.84597844
35ETS1_20019798_ChIP-Seq_JURKAT_Human1.83996272
36RNF2_27304074_Chip-Seq_NSC_Mouse1.80744183
37JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.80444599
38FLI1_27457419_Chip-Seq_LIVER_Mouse1.77197825
39BMI1_23680149_ChIP-Seq_NPCS_Mouse1.75362671
40MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.75344841
41EWS_26573619_Chip-Seq_HEK293_Human1.74854508
42VDR_22108803_ChIP-Seq_LS180_Human1.73597856
43SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.71238556
44EZH2_27304074_Chip-Seq_ESCs_Mouse1.70610216
45RARB_27405468_Chip-Seq_BRAIN_Mouse1.69827279
46MYC_18940864_ChIP-ChIP_HL60_Human1.68297206
47REST_18959480_ChIP-ChIP_MESCs_Mouse1.67033584
48PADI4_21655091_ChIP-ChIP_MCF-7_Human1.66519446
49PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.65580572
50E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.59227320
51CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54703564
52PCGF2_27294783_Chip-Seq_ESCs_Mouse1.52951237
53NANOG_18555785_Chip-Seq_ESCs_Mouse1.51313437
54YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.48900062
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.47531671
56CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.46961752
57OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.45366518
58STAT3_23295773_ChIP-Seq_U87_Human1.44745069
59AR_25329375_ChIP-Seq_VCAP_Human1.44028246
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.43912221
61* POU5F1_16153702_ChIP-ChIP_HESCs_Human1.43838718
62SMAD3_21741376_ChIP-Seq_EPCs_Human1.43769787
63JARID2_20075857_ChIP-Seq_MESCs_Mouse1.43425252
64TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.42097856
65GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.41445211
66AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.41433005
67SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.40931218
68KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.39846095
69EZH2_18974828_ChIP-Seq_MESCs_Mouse1.39523409
70RNF2_18974828_ChIP-Seq_MESCs_Mouse1.39523409
71MTF2_20144788_ChIP-Seq_MESCs_Mouse1.38746003
72FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.37636130
73MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.37607985
74RNF2_27304074_Chip-Seq_ESCs_Mouse1.37545293
75TCF4_23295773_ChIP-Seq_U87_Human1.37344280
76JUN_21703547_ChIP-Seq_K562_Human1.37010430
77SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.36092573
78UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.35005369
79ER_23166858_ChIP-Seq_MCF-7_Human1.34619915
80CBX2_27304074_Chip-Seq_ESCs_Mouse1.33960604
81P53_22127205_ChIP-Seq_FIBROBLAST_Human1.33150324
82IRF1_19129219_ChIP-ChIP_H3396_Human1.32681514
83CBP_20019798_ChIP-Seq_JUKART_Human1.31338461
84IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.31338461
85SRF_21415370_ChIP-Seq_HL-1_Mouse1.28578506
86SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.27280156
87SOX2_21211035_ChIP-Seq_LN229_Gbm1.27106461
88SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26339819
89FOXP3_21729870_ChIP-Seq_TREG_Human1.26231189
90SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.24622495
91MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.24436450
92TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.24386707
93MYC_18555785_ChIP-Seq_MESCs_Mouse1.24200927
94RUNX2_22187159_ChIP-Seq_PCA_Human1.22134962
95DCP1A_22483619_ChIP-Seq_HELA_Human1.22120304
96AR_21572438_ChIP-Seq_LNCaP_Human1.20627710
97THAP11_20581084_ChIP-Seq_MESCs_Mouse1.20442705
98PRDM14_20953172_ChIP-Seq_ESCs_Human1.20249720
99E2F1_18555785_Chip-Seq_ESCs_Mouse1.19587340
100TP53_16413492_ChIP-PET_HCT116_Human1.19030478
101NR3C1_23031785_ChIP-Seq_PC12_Mouse1.18854243
102SALL1_21062744_ChIP-ChIP_HESCs_Human1.18788843
103SOX2_16153702_ChIP-ChIP_HESCs_Human1.18216689
104BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.16998935
105EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.16121505
106TP63_19390658_ChIP-ChIP_HaCaT_Human1.16083301
107RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.15812452
108CMYC_18555785_Chip-Seq_ESCs_Mouse1.13955378
109GABP_19822575_ChIP-Seq_HepG2_Human1.13697927
110SUZ12_27294783_Chip-Seq_ESCs_Mouse1.13455502
111EED_16625203_ChIP-ChIP_MESCs_Mouse1.12913184
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12681790
113POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.12681790
114TP53_22573176_ChIP-Seq_HFKS_Human1.12159162
115SUZ12_27294783_Chip-Seq_NPCs_Mouse1.11577930
116ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.10834156
117FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.09558086
118SOX9_26525672_Chip-Seq_HEART_Mouse1.09022557
119PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.08562649
120P53_22387025_ChIP-Seq_ESCs_Mouse1.08530135
121EZH2_27294783_Chip-Seq_ESCs_Mouse1.08507617
122MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.08292886
123SOX2_18555785_Chip-Seq_ESCs_Mouse1.07486275
124CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.07017742
125PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.05512041
126SUZ12_18555785_Chip-Seq_ESCs_Mouse1.04366806
127ZNF274_21170338_ChIP-Seq_K562_Hela1.04238521
128BCAT_22108803_ChIP-Seq_LS180_Human1.04041011
129YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03497079
130TTF2_22483619_ChIP-Seq_HELA_Human1.02035120
131STAT3_18555785_Chip-Seq_ESCs_Mouse1.01855026
132NANOG_16153702_ChIP-ChIP_HESCs_Human1.01012799
133EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.00835684
134TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00107696
135LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98992181
136RBPJ_22232070_ChIP-Seq_NCS_Mouse0.98818111
137IKZF1_21737484_ChIP-ChIP_HCT116_Human0.98162690
138KLF5_20875108_ChIP-Seq_MESCs_Mouse0.97997642
139FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.97015440
140EZH2_27294783_Chip-Seq_NPCs_Mouse0.96071449
141HOXB4_20404135_ChIP-ChIP_EML_Mouse0.95184050
142HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.95023400
143FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.93815853
144GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.93016565
145TAL1_26923725_Chip-Seq_HPCs_Mouse0.92778824
146ELK1_22589737_ChIP-Seq_MCF10A_Human0.91830781
147MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.91304203

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.28298648
2MP0004859_abnormal_synaptic_plasticity4.23989775
3MP0003635_abnormal_synaptic_transmissio3.29421724
4MP0004270_analgesia3.14238840
5MP0008877_abnormal_DNA_methylation2.96738818
6MP0009745_abnormal_behavioral_response2.80173915
7MP0001968_abnormal_touch/_nociception2.78927670
8MP0006292_abnormal_olfactory_placode2.73521435
9MP0002822_catalepsy2.70303713
10MP0003787_abnormal_imprinting2.67675854
11MP0002063_abnormal_learning/memory/cond2.66140165
12MP0006276_abnormal_autonomic_nervous2.58268436
13MP0002064_seizures2.55318177
14MP0002734_abnormal_mechanical_nocicepti2.48138539
15MP0002572_abnormal_emotion/affect_behav2.44710182
16MP0009046_muscle_twitch2.33358879
17MP0002735_abnormal_chemical_nociception2.29788911
18MP0002736_abnormal_nociception_after2.22931502
19MP0002272_abnormal_nervous_system2.21398343
20MP0001529_abnormal_vocalization2.21105815
21MP0003890_abnormal_embryonic-extraembry2.17801186
22MP0001188_hyperpigmentation2.13085607
23MP0009697_abnormal_copulation2.11729507
24MP0000569_abnormal_digit_pigmentation2.08429671
25MP0001905_abnormal_dopamine_level1.96991559
26MP0001984_abnormal_olfaction1.88037369
27MP0001501_abnormal_sleep_pattern1.82601677
28MP0010386_abnormal_urinary_bladder1.78556248
29MP0002067_abnormal_sensory_capabilities1.77050934
30MP0002733_abnormal_thermal_nociception1.76547159
31MP0004133_heterotaxia1.73808368
32MP0005386_behavior/neurological_phenoty1.73147068
33MP0004924_abnormal_behavior1.73147068
34MP0005646_abnormal_pituitary_gland1.71342407
35MP0002938_white_spotting1.70952985
36MP0001970_abnormal_pain_threshold1.70409104
37MP0001486_abnormal_startle_reflex1.68883736
38MP0002184_abnormal_innervation1.67171867
39MP0001502_abnormal_circadian_rhythm1.64692603
40MP0003123_paternal_imprinting1.63224075
41MP0001440_abnormal_grooming_behavior1.62517889
42MP0003879_abnormal_hair_cell1.58503428
43MP0000778_abnormal_nervous_system1.52736266
44MP0005499_abnormal_olfactory_system1.50368569
45MP0005394_taste/olfaction_phenotype1.50368569
46MP0003121_genomic_imprinting1.49570104
47MP0008995_early_reproductive_senescence1.46143566
48MP0005423_abnormal_somatic_nervous1.45769271
49MP0002102_abnormal_ear_morphology1.45516096
50MP0005084_abnormal_gallbladder_morpholo1.44787439
51MP0002557_abnormal_social/conspecific_i1.38043656
52MP0003937_abnormal_limbs/digits/tail_de1.37825575
53MP0008789_abnormal_olfactory_epithelium1.32527172
54MP0002638_abnormal_pupillary_reflex1.32129342
55MP0004811_abnormal_neuron_physiology1.30160513
56MP0003119_abnormal_digestive_system1.29288527
57MP0001986_abnormal_taste_sensitivity1.27473031
58MP0002277_abnormal_respiratory_mucosa1.25250836
59MP0008569_lethality_at_weaning1.24681571
60MP0008932_abnormal_embryonic_tissue1.24576889
61MP0006035_abnormal_mitochondrial_morpho1.23462831
62MP0000955_abnormal_spinal_cord1.23456842
63MP0000631_abnormal_neuroendocrine_gland1.23148087
64MP0003195_calcinosis1.23052361
65MP0000516_abnormal_urinary_system1.22369114
66MP0005367_renal/urinary_system_phenotyp1.22369114
67MP0003122_maternal_imprinting1.21525310
68MP0002233_abnormal_nose_morphology1.19774017
69MP0009780_abnormal_chondrocyte_physiolo1.19416891
70MP0002837_dystrophic_cardiac_calcinosis1.19403148
71MP0008007_abnormal_cellular_replicative1.18374792
72MP0001293_anophthalmia1.15957803
73MP0002282_abnormal_trachea_morphology1.15573019
74MP0000647_abnormal_sebaceous_gland1.15426113
75MP0002882_abnormal_neuron_morphology1.14100371
76MP0003567_abnormal_fetal_cardiomyocyte1.12453056
77MP0004043_abnormal_pH_regulation1.11841658
78MP0004145_abnormal_muscle_electrophysio1.11393814
79MP0002066_abnormal_motor_capabilities/c1.11105572
80MP0005187_abnormal_penis_morphology1.10440577
81MP0002909_abnormal_adrenal_gland1.08770877
82MP0005551_abnormal_eye_electrophysiolog1.06182853
83MP0003786_premature_aging1.06136701
84MP0006072_abnormal_retinal_apoptosis1.04673189
85MP0002090_abnormal_vision1.04589482
86MP0004147_increased_porphyrin_level1.04438218
87MP0004957_abnormal_blastocyst_morpholog0.96931137
88MP0004142_abnormal_muscle_tone0.96841177
89MP0008058_abnormal_DNA_repair0.95860442
90MP0003077_abnormal_cell_cycle0.95715489
91MP0002152_abnormal_brain_morphology0.94458381
92MP0004742_abnormal_vestibular_system0.94354350
93MP0002928_abnormal_bile_duct0.93298063
94MP0003136_yellow_coat_color0.92995850
95MP0001299_abnormal_eye_distance/0.92002371
96MP0000566_synostosis0.91791009
97MP0008057_abnormal_DNA_replication0.89710733
98MP0000372_irregular_coat_pigmentation0.88569452
99MP0003111_abnormal_nucleus_morphology0.88491046
100MP0005248_abnormal_Harderian_gland0.87073235
101MP0001286_abnormal_eye_development0.86544701
102MP0001764_abnormal_homeostasis0.86470369
103MP0001963_abnormal_hearing_physiology0.86253676
104MP0003385_abnormal_body_wall0.85789062
105MP0000049_abnormal_middle_ear0.85366661
106MP0002751_abnormal_autonomic_nervous0.85180051
107MP0003718_maternal_effect0.84294138
108MP0005391_vision/eye_phenotype0.83316423
109MP0002752_abnormal_somatic_nervous0.81573159
110MP0005310_abnormal_salivary_gland0.74256815
111MP0003646_muscle_fatigue0.73718373
112MP0005379_endocrine/exocrine_gland_phen0.73580762
113MP0001485_abnormal_pinna_reflex0.73502452
114MP0001929_abnormal_gametogenesis0.72548479
115MP0002653_abnormal_ependyma_morphology0.71747143
116MP0003183_abnormal_peptide_metabolism0.70374303
117MP0002229_neurodegeneration0.70026917
118MP0000013_abnormal_adipose_tissue0.66594230
119MP0005645_abnormal_hypothalamus_physiol0.66210879
120MP0000015_abnormal_ear_pigmentation0.66185329
121MP0003861_abnormal_nervous_system0.66163002
122MP0003698_abnormal_male_reproductive0.66006135
123MP0003631_nervous_system_phenotype0.65202296
124MP0002210_abnormal_sex_determination0.63526645
125MP0003329_amyloid_beta_deposits0.62171701
126MP0004085_abnormal_heartbeat0.62095078
127MP0004215_abnormal_myocardial_fiber0.62031808
128MP0000653_abnormal_sex_gland0.61525557
129MP0002127_abnormal_cardiovascular_syste0.59451396
130MP0002163_abnormal_gland_morphology0.59126615
131MP0002876_abnormal_thyroid_physiology0.58931930
132MP0010094_abnormal_chromosome_stability0.58474543
133MP0002234_abnormal_pharynx_morphology0.58058528
134MP0003633_abnormal_nervous_system0.57972713
135MP0002069_abnormal_eating/drinking_beha0.55714627
136MP0005253_abnormal_eye_physiology0.54638942
137MP0008874_decreased_physiological_sensi0.54186730
138MP0003693_abnormal_embryo_hatching0.53125695
139MP0005408_hypopigmentation0.50688915
140MP0008872_abnormal_physiological_respon0.50073209

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.27936706
2Atonic seizures (HP:0010819)5.22949629
3Epileptic encephalopathy (HP:0200134)4.66006395
4Febrile seizures (HP:0002373)4.63827608
5Focal seizures (HP:0007359)4.34892064
6Absence seizures (HP:0002121)3.80262659
7Visual hallucinations (HP:0002367)3.66161807
8Hyperventilation (HP:0002883)3.61396372
9Dialeptic seizures (HP:0011146)3.53144037
10Abnormal hair whorl (HP:0010721)3.44719847
11Abnormality of the labia minora (HP:0012880)3.21719773
12Gait imbalance (HP:0002141)3.21713664
13True hermaphroditism (HP:0010459)3.18173007
14Protruding tongue (HP:0010808)3.15049922
15Myokymia (HP:0002411)3.07961307
16Acute encephalopathy (HP:0006846)3.07508489
17Medial flaring of the eyebrow (HP:0010747)3.04515784
18Colon cancer (HP:0003003)3.03390942
19Congenital primary aphakia (HP:0007707)3.03282726
20Hypothermia (HP:0002045)2.98829774
21Nephronophthisis (HP:0000090)2.98053781
22Progressive cerebellar ataxia (HP:0002073)2.97951726
23Hepatocellular necrosis (HP:0001404)2.97688429
24Increased hepatocellular lipid droplets (HP:0006565)2.93326081
25Broad-based gait (HP:0002136)2.85945127
26Increased CSF lactate (HP:0002490)2.84987243
27Nephrogenic diabetes insipidus (HP:0009806)2.84951576
28Hepatic necrosis (HP:0002605)2.79590267
29Generalized tonic-clonic seizures (HP:0002069)2.77826982
30Aplasia/Hypoplasia of the uvula (HP:0010293)2.75422602
31Lipid accumulation in hepatocytes (HP:0006561)2.72158507
32Birth length less than 3rd percentile (HP:0003561)2.67929672
33Drooling (HP:0002307)2.64075867
34Excessive salivation (HP:0003781)2.64075867
35Gaze-evoked nystagmus (HP:0000640)2.62740450
36Poor coordination (HP:0002370)2.62618150
37Inability to walk (HP:0002540)2.61632578
38Meckel diverticulum (HP:0002245)2.60615694
39Methylmalonic acidemia (HP:0002912)2.60500646
40Progressive inability to walk (HP:0002505)2.59715712
41Abnormality of the ileum (HP:0001549)2.51992830
42Shoulder girdle muscle weakness (HP:0003547)2.51300285
43Pancreatic fibrosis (HP:0100732)2.49774602
44Bifid tongue (HP:0010297)2.48561871
45Papillary thyroid carcinoma (HP:0002895)2.46222105
46Genital tract atresia (HP:0001827)2.45729906
47Truncal ataxia (HP:0002078)2.45439122
48Abnormality of the renal medulla (HP:0100957)2.38672236
49Ependymoma (HP:0002888)2.34540424
50Amblyopia (HP:0000646)2.33745060
51Vaginal atresia (HP:0000148)2.32665175
52Glioma (HP:0009733)2.32484249
53Renal Fanconi syndrome (HP:0001994)2.31319231
54Epileptiform EEG discharges (HP:0011182)2.31281493
55Abnormality of chromosome stability (HP:0003220)2.27662981
56Absent speech (HP:0001344)2.26394284
57Facial hemangioma (HP:0000329)2.25409573
58Hyperglycinemia (HP:0002154)2.24544354
59Aplasia/Hypoplasia of the tongue (HP:0010295)2.24255117
60Cerebral edema (HP:0002181)2.23929282
61Medulloblastoma (HP:0002885)2.23313031
62Poor eye contact (HP:0000817)2.22297349
63Fair hair (HP:0002286)2.21495120
64Abnormality of lateral ventricle (HP:0030047)2.20509079
65Astrocytoma (HP:0009592)2.16424994
66Abnormality of the astrocytes (HP:0100707)2.16424994
67Acute necrotizing encephalopathy (HP:0006965)2.14007156
68Fetal akinesia sequence (HP:0001989)2.09784495
69EEG with generalized epileptiform discharges (HP:0011198)2.08579158
70Sclerocornea (HP:0000647)2.08510080
71Dysdiadochokinesis (HP:0002075)2.08502058
72Volvulus (HP:0002580)2.06179041
73Menstrual irregularities (HP:0000858)2.05859414
74Aplasia/Hypoplasia of the tibia (HP:0005772)2.04874287
75Methylmalonic aciduria (HP:0012120)2.04255170
76Lissencephaly (HP:0001339)2.04130638
77Abnormality of the preputium (HP:0100587)2.01644517
78Retinal dysplasia (HP:0007973)1.99074149
79Labial hypoplasia (HP:0000066)1.97330463
80Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.97238983
81Thyroid carcinoma (HP:0002890)1.96361367
82Anencephaly (HP:0002323)1.95954943
83Tubulointerstitial nephritis (HP:0001970)1.95483824
84Generalized hypopigmentation of hair (HP:0011358)1.95458294
85Delusions (HP:0000746)1.94849458
86Polyphagia (HP:0002591)1.94734816
87Bile duct proliferation (HP:0001408)1.94650422
88Abnormal biliary tract physiology (HP:0012439)1.94650422
89Abnormal mitochondria in muscle tissue (HP:0008316)1.93985464
90Hypoplastic female external genitalia (HP:0012815)1.93801575
91Impaired vibration sensation in the lower limbs (HP:0002166)1.93460759
92Progressive macrocephaly (HP:0004481)1.92738499
93Degeneration of anterior horn cells (HP:0002398)1.92586337
94Abnormality of the anterior horn cell (HP:0006802)1.92586337
95Increased serum lactate (HP:0002151)1.91547958
96Urinary bladder sphincter dysfunction (HP:0002839)1.90193381
97Short tibia (HP:0005736)1.89629700
98Abnormality of methionine metabolism (HP:0010901)1.88922927
99Lactic acidosis (HP:0003128)1.83873567
100Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.83491376
101Decreased activity of mitochondrial respiratory chain (HP:0008972)1.83491376
102Severe visual impairment (HP:0001141)1.83277652
103Abnormality of salivation (HP:0100755)1.83233938
104Specific learning disability (HP:0001328)1.82021321
105Hypsarrhythmia (HP:0002521)1.81057406
106Preaxial hand polydactyly (HP:0001177)1.80967546
107Limb dystonia (HP:0002451)1.80693249
108Postaxial hand polydactyly (HP:0001162)1.79537104
109Type II lissencephaly (HP:0007260)1.79126060
110Generalized aminoaciduria (HP:0002909)1.78954790
111Hypoplastic pelvis (HP:0008839)1.78723740
112Aplasia/Hypoplasia of the lens (HP:0008063)1.78595738
113Abnormality of the renal cortex (HP:0011035)1.78445822
114Narrow forehead (HP:0000341)1.78370812
115Oligodactyly (hands) (HP:0001180)1.77681666
116Abnormal social behavior (HP:0012433)1.76823707
117Impaired social interactions (HP:0000735)1.76823707
118Atrophy/Degeneration involving motor neurons (HP:0007373)1.76324920
119Optic nerve hypoplasia (HP:0000609)1.76117241
120Increased serum pyruvate (HP:0003542)1.75253768
121Cystic liver disease (HP:0006706)1.75182625
122Unsteady gait (HP:0002317)1.75072896
123Dysmetria (HP:0001310)1.74286423
124Duodenal stenosis (HP:0100867)1.73821438
125Small intestinal stenosis (HP:0012848)1.73821438
126Abnormality of vitamin B metabolism (HP:0004340)1.73791628
127Type I transferrin isoform profile (HP:0003642)1.73531919
128Supernumerary spleens (HP:0009799)1.71995131
129Neoplasm of the adrenal gland (HP:0100631)1.71370893
130Gastroesophageal reflux (HP:0002020)1.71244415
131Thickened helices (HP:0000391)1.70575293
132Capillary hemangiomas (HP:0005306)1.70276257
133Abnormal eating behavior (HP:0100738)1.70269702
134Increased intramyocellular lipid droplets (HP:0012240)1.69907153
135Abnormality of the vitamin B12 metabolism (HP:0004341)1.69837883
136Respiratory failure (HP:0002878)1.69801510
137Pachygyria (HP:0001302)1.69213672
138Aganglionic megacolon (HP:0002251)1.69171072
139Abnormality of urine glucose concentration (HP:0011016)1.69044283
140Glycosuria (HP:0003076)1.69044283
141Stereotypic behavior (HP:0000733)1.68405605
142Abnormality of renal resorption (HP:0011038)1.68203306
143Sensory axonal neuropathy (HP:0003390)1.68116394
144Renal cortical cysts (HP:0000803)1.68106892
145Esotropia (HP:0000565)1.66394495
146Genetic anticipation (HP:0003743)1.64123534
147Amyotrophic lateral sclerosis (HP:0007354)1.63529232
148Generalized myoclonic seizures (HP:0002123)1.62322640
149Pancreatic cysts (HP:0001737)1.59490127
150Abnormality of the labia (HP:0000058)1.59483404
151Broad foot (HP:0001769)1.58935059
152Hypoplastic iliac wings (HP:0002866)1.58326957
153Absent eyebrow (HP:0002223)1.56885147
154Congenital stationary night blindness (HP:0007642)1.56600166
155Decreased lacrimation (HP:0000633)1.56455713
156Impaired smooth pursuit (HP:0007772)1.52978230
157Aplasia/Hypoplasia of the fovea (HP:0008060)1.52489301
158Hypoplasia of the fovea (HP:0007750)1.52489301
159Abnormality of the musculature of the pelvis (HP:0001469)1.51990345
160Abnormality of the hip-girdle musculature (HP:0001445)1.51990345
161Abnormality of the clitoris (HP:0000056)1.50385629
162Pelvic girdle muscle weakness (HP:0003749)1.49198933
163Mitochondrial inheritance (HP:0001427)1.47907814
164Abnormality of midbrain morphology (HP:0002418)1.47562649
165Molar tooth sign on MRI (HP:0002419)1.47562649
166Septate vagina (HP:0001153)1.47178018
167Abnormality of the corticospinal tract (HP:0002492)1.46983545
168Breast hypoplasia (HP:0003187)1.46944021

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.05094311
2TNIK3.84499135
3MAP3K43.61936080
4CASK3.51224085
5MAP2K73.34923041
6EPHA43.34175983
7MAP3K122.73674477
8BRSK22.72676010
9ZAK2.71596996
10MAP4K22.56307940
11TRIM282.34388033
12MAP3K92.33846348
13FRK2.33326747
14MKNK12.32589679
15PLK22.10814550
16CDK192.06687742
17MST42.05079150
18DAPK22.00420966
19PNCK1.83247983
20BUB11.81017062
21MAP3K61.77995036
22BMPR1B1.72577216
23MAP2K41.71733484
24ARAF1.71379554
25CCNB11.69734461
26DAPK11.68774557
27MAPK131.60749858
28AKT31.56653178
29RAF11.54492444
30NUAK11.54415913
31ERBB31.52017604
32GRK51.50857885
33BRAF1.44336244
34BMPR21.44046194
35MINK11.43499728
36CDK81.40877657
37PRPF4B1.40233121
38CDK31.36566315
39TAOK31.36213718
40MUSK1.32813713
41KSR11.31779684
42MARK11.30849549
43DYRK31.28540351
44LIMK11.26705427
45LATS21.26432278
46KSR21.25516280
47MAPK151.24814479
48NTRK21.20469013
49PAK61.19072006
50CSNK1G11.17716429
51PINK11.15790139
52CDC71.14113294
53NEK11.05932934
54TTK1.05692863
55WEE11.04609577
56SGK21.02484960
57PLK11.01978942
58CAMKK21.00417189
59BRD41.00289089
60VRK20.99073268
61CAMK2A0.97779400
62WNK30.96259438
63RIPK40.95273129
64CSNK1A1L0.95168302
65PAK30.93913392
66PLK30.92580724
67STK38L0.91568771
68RPS6KA40.90170667
69BRSK10.90169626
70OXSR10.89716599
71CDK50.86705444
72SGK4940.86655223
73SGK2230.86655223
74TAF10.85671823
75FGFR20.82081999
76DYRK1A0.80344108
77BCKDK0.78652177
78NLK0.78300858
79TAOK10.77448700
80NME10.76220158
81NTRK10.74627048
82ATR0.71910686
83PRKCG0.69139845
84RPS6KA50.68777829
85CSNK1G20.68668455
86STK160.68561629
87PLK40.67253260
88SIK30.65784482
89DYRK20.65667790
90BCR0.64688976
91ERBB40.63702933
92GRK10.62950341
93FES0.62793140
94MKNK20.61968115
95CAMK2B0.60340172
96ATM0.60260819
97TSSK60.59103020
98PHKG10.58340095
99PHKG20.58340095
100UHMK10.57734904
101MOS0.57104602
102VRK10.55090778
103STK240.54456493
104EIF2AK20.54000813
105CDK180.53597114
106FER0.53272559
107EPHA30.52278158
108SIK20.51576379
109PTK2B0.51325830
110FGR0.50795744
111SRPK10.50682883
112PASK0.50586704
113MAP3K130.48738844
114FLT30.47456902
115HIPK20.47432652
116CDK150.47156722
117CDK140.46380981
118CDC42BPA0.46134333
119ADRBK20.45942794
120CHEK20.45686326
121MARK20.44755017
122YES10.44680693
123TGFBR10.44598899
124STK380.44582092
125MAP3K50.44500845
126PRKCE0.44381348
127ACVR1B0.44305418
128EIF2AK30.43354668
129CDK11A0.42990405
130CSNK1E0.41730306
131INSRR0.41708011
132CSNK1A10.41613631
133GRK70.41288550
134CAMK10.41272502
135TXK0.40322485
136SGK10.40270668
137ADRBK10.39431256
138PKN10.39099985
139CAMK2D0.39023452
140MAPK100.35945769
141TLK10.35357140
142ROCK20.35104854
143MAPKAPK50.34644611
144PRKACB0.34618098
145CSNK1D0.33341092
146SGK30.33066864
147NEK60.33065053
148CSNK2A10.32944939
149CSNK1G30.32135955
150LATS10.31497989
151AURKB0.30016389
152PRKCZ0.29789065

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.77996246
2Protein export_Homo sapiens_hsa030603.59199029
3Synaptic vesicle cycle_Homo sapiens_hsa047213.22790479
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.61371552
5Long-term potentiation_Homo sapiens_hsa047202.58679002
6Mismatch repair_Homo sapiens_hsa034302.54176603
7Amphetamine addiction_Homo sapiens_hsa050312.49863961
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.34936125
9Collecting duct acid secretion_Homo sapiens_hsa049662.28430984
10Olfactory transduction_Homo sapiens_hsa047402.26752663
11Fanconi anemia pathway_Homo sapiens_hsa034602.20093193
12Morphine addiction_Homo sapiens_hsa050322.13410162
13Glutamatergic synapse_Homo sapiens_hsa047242.12808272
14Dopaminergic synapse_Homo sapiens_hsa047282.10910235
15GABAergic synapse_Homo sapiens_hsa047272.09865616
16Circadian entrainment_Homo sapiens_hsa047132.06384871
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.99643877
18Serotonergic synapse_Homo sapiens_hsa047261.97244166
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.95825613
20Propanoate metabolism_Homo sapiens_hsa006401.92207218
21Taste transduction_Homo sapiens_hsa047421.86234924
22Steroid biosynthesis_Homo sapiens_hsa001001.83684989
23Selenocompound metabolism_Homo sapiens_hsa004501.78105521
24Insulin secretion_Homo sapiens_hsa049111.77755476
25Long-term depression_Homo sapiens_hsa047301.75937405
26Circadian rhythm_Homo sapiens_hsa047101.72017358
27Homologous recombination_Homo sapiens_hsa034401.71874462
28Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.63548142
29DNA replication_Homo sapiens_hsa030301.58620743
30Butanoate metabolism_Homo sapiens_hsa006501.58289056
31Spliceosome_Homo sapiens_hsa030401.57350882
32Basal transcription factors_Homo sapiens_hsa030221.56689365
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.55465921
34Nucleotide excision repair_Homo sapiens_hsa034201.52567546
35Cholinergic synapse_Homo sapiens_hsa047251.51818241
36Oxytocin signaling pathway_Homo sapiens_hsa049211.51636961
37Phototransduction_Homo sapiens_hsa047441.51164578
38Base excision repair_Homo sapiens_hsa034101.47838878
39Renin secretion_Homo sapiens_hsa049241.47639675
40Cocaine addiction_Homo sapiens_hsa050301.46663294
41Salivary secretion_Homo sapiens_hsa049701.45162576
42Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.40377217
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.38681808
44GnRH signaling pathway_Homo sapiens_hsa049121.36622195
45Fatty acid elongation_Homo sapiens_hsa000621.35858184
46Oocyte meiosis_Homo sapiens_hsa041141.35519110
47Aldosterone synthesis and secretion_Homo sapiens_hsa049251.35010359
48Calcium signaling pathway_Homo sapiens_hsa040201.34808786
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.26977514
50Oxidative phosphorylation_Homo sapiens_hsa001901.24303195
512-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.21753178
52Tryptophan metabolism_Homo sapiens_hsa003801.20152215
53Vibrio cholerae infection_Homo sapiens_hsa051101.18620963
54ErbB signaling pathway_Homo sapiens_hsa040121.14433173
55Sulfur metabolism_Homo sapiens_hsa009201.12070466
56RNA degradation_Homo sapiens_hsa030181.10715273
57Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.10697321
58Maturity onset diabetes of the young_Homo sapiens_hsa049501.08906353
59RNA polymerase_Homo sapiens_hsa030201.05804039
60cAMP signaling pathway_Homo sapiens_hsa040241.05760846
61Linoleic acid metabolism_Homo sapiens_hsa005911.05316574
62Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.04735207
63One carbon pool by folate_Homo sapiens_hsa006701.04685073
64Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.01051738
65Gastric acid secretion_Homo sapiens_hsa049710.99400288
66alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.98924880
67Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.97422735
68Axon guidance_Homo sapiens_hsa043600.96728058
69Cysteine and methionine metabolism_Homo sapiens_hsa002700.96684830
70Estrogen signaling pathway_Homo sapiens_hsa049150.96081056
71Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.95221689
72Choline metabolism in cancer_Homo sapiens_hsa052310.93639368
73Pyrimidine metabolism_Homo sapiens_hsa002400.92888125
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.92687491
75Alzheimers disease_Homo sapiens_hsa050100.92505857
76Gap junction_Homo sapiens_hsa045400.92070794
77Folate biosynthesis_Homo sapiens_hsa007900.90520560
78Ribosome_Homo sapiens_hsa030100.90042340
79Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.89682448
80cGMP-PKG signaling pathway_Homo sapiens_hsa040220.88940698
81Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.87679566
82Glioma_Homo sapiens_hsa052140.87603110
83Huntingtons disease_Homo sapiens_hsa050160.86647055
84Vascular smooth muscle contraction_Homo sapiens_hsa042700.86234902
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.85628235
86Parkinsons disease_Homo sapiens_hsa050120.83042368
87Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.82052657
88Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.80828900
89MAPK signaling pathway_Homo sapiens_hsa040100.79082059
90Melanogenesis_Homo sapiens_hsa049160.77475510
91Cardiac muscle contraction_Homo sapiens_hsa042600.76938691
92Ovarian steroidogenesis_Homo sapiens_hsa049130.76703595
93Ras signaling pathway_Homo sapiens_hsa040140.74100564
94Regulation of autophagy_Homo sapiens_hsa041400.73305216
95Cell cycle_Homo sapiens_hsa041100.72453091
96Pentose and glucuronate interconversions_Homo sapiens_hsa000400.71883328
97Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.71806673
98Metabolic pathways_Homo sapiens_hsa011000.71671566
99Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.71014497
100Pyruvate metabolism_Homo sapiens_hsa006200.70606857
101Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.68211180
102Colorectal cancer_Homo sapiens_hsa052100.67309412
103Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.66978319
104Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.66908515
105Non-homologous end-joining_Homo sapiens_hsa034500.66649647
106SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66220971
107Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.64847315
108Type II diabetes mellitus_Homo sapiens_hsa049300.63319876
109Wnt signaling pathway_Homo sapiens_hsa043100.62357399
110Peroxisome_Homo sapiens_hsa041460.61539959
111VEGF signaling pathway_Homo sapiens_hsa043700.60872696
112Fatty acid metabolism_Homo sapiens_hsa012120.60291000
113Thyroid cancer_Homo sapiens_hsa052160.60280427
114Proteasome_Homo sapiens_hsa030500.59141625
115Prolactin signaling pathway_Homo sapiens_hsa049170.58897647
116Ether lipid metabolism_Homo sapiens_hsa005650.57747435
117Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.57615431
118Rheumatoid arthritis_Homo sapiens_hsa053230.57465551
119Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.56835114
120mRNA surveillance pathway_Homo sapiens_hsa030150.55004273
121Glucagon signaling pathway_Homo sapiens_hsa049220.54516194
122Endometrial cancer_Homo sapiens_hsa052130.53718843
123Phospholipase D signaling pathway_Homo sapiens_hsa040720.53189410
124Type I diabetes mellitus_Homo sapiens_hsa049400.52483203
125Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.52428318
126Alcoholism_Homo sapiens_hsa050340.51841622
127Dorso-ventral axis formation_Homo sapiens_hsa043200.51730436
128RNA transport_Homo sapiens_hsa030130.50940076
129Renal cell carcinoma_Homo sapiens_hsa052110.50695565
130N-Glycan biosynthesis_Homo sapiens_hsa005100.50677890
131Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.50312947
132Primary bile acid biosynthesis_Homo sapiens_hsa001200.50233410
133Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49931636
134Caffeine metabolism_Homo sapiens_hsa002320.49208642
135Hedgehog signaling pathway_Homo sapiens_hsa043400.49185304
136Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.46478135
137Thyroid hormone signaling pathway_Homo sapiens_hsa049190.45643139
138Nitrogen metabolism_Homo sapiens_hsa009100.45249209
139Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.44102438
140Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.43657252
141Glutathione metabolism_Homo sapiens_hsa004800.43595557
142Retinol metabolism_Homo sapiens_hsa008300.43373848
143Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.43122931
144Pancreatic cancer_Homo sapiens_hsa052120.42085366
145beta-Alanine metabolism_Homo sapiens_hsa004100.41716502
146Carbon metabolism_Homo sapiens_hsa012000.41228173
147FoxO signaling pathway_Homo sapiens_hsa040680.41061797
148Inositol phosphate metabolism_Homo sapiens_hsa005620.40566610
149Dilated cardiomyopathy_Homo sapiens_hsa054140.40100782
150Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.39280579
151Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.39052294
152Basal cell carcinoma_Homo sapiens_hsa052170.39014533
153Sphingolipid signaling pathway_Homo sapiens_hsa040710.38218436
154Purine metabolism_Homo sapiens_hsa002300.37566191
155Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.36143683
156T cell receptor signaling pathway_Homo sapiens_hsa046600.34931676
157Pancreatic secretion_Homo sapiens_hsa049720.33553649
158Neurotrophin signaling pathway_Homo sapiens_hsa047220.33216389

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