ARMCX6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1gonadal mesoderm development (GO:0007506)9.10899525
2protein neddylation (GO:0045116)6.92300694
3ribosomal small subunit assembly (GO:0000028)5.67737391
4response to pheromone (GO:0019236)5.53861216
5sequestering of actin monomers (GO:0042989)5.34061585
6regulation of integrin-mediated signaling pathway (GO:2001044)5.27136534
7peptidyl-arginine omega-N-methylation (GO:0035247)5.27122518
8extracellular fibril organization (GO:0043206)4.89135870
9viral transcription (GO:0019083)4.86744413
10protein maturation by protein folding (GO:0022417)4.83931495
11translational termination (GO:0006415)4.68779187
12peptidyl-arginine methylation (GO:0018216)4.62846076
13peptidyl-arginine N-methylation (GO:0035246)4.62846076
14fibril organization (GO:0097435)4.51135435
15positive regulation of mitochondrial calcium ion concentration (GO:0051561)4.39283902
16mitochondrial calcium ion transport (GO:0006851)4.23699968
17translational elongation (GO:0006414)4.15491990
18histone arginine methylation (GO:0034969)4.11662965
19SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.07254753
20DNA unwinding involved in DNA replication (GO:0006268)4.01479740
21cotranslational protein targeting to membrane (GO:0006613)3.99467673
22protein targeting to ER (GO:0045047)3.95690824
23COPI coating of Golgi vesicle (GO:0048205)3.94211680
24Golgi transport vesicle coating (GO:0048200)3.94211680
25nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.83398650
26viral life cycle (GO:0019058)3.75265979
27establishment of protein localization to endoplasmic reticulum (GO:0072599)3.73912749
28protein localization to endoplasmic reticulum (GO:0070972)3.73743680
29cellular protein complex disassembly (GO:0043624)3.73248527
30ribosomal small subunit biogenesis (GO:0042274)3.73123856
31platelet aggregation (GO:0070527)3.72536356
32maturation of SSU-rRNA (GO:0030490)3.69397326
33thrombin receptor signaling pathway (GO:0070493)3.66481912
34deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.57390197
35viral mRNA export from host cell nucleus (GO:0046784)3.57322778
36definitive hemopoiesis (GO:0060216)3.53975028
37protein complex disassembly (GO:0043241)3.50879526
38DNA deamination (GO:0045006)3.50360066
39negative regulation of smooth muscle cell migration (GO:0014912)3.48502481
40positive regulation of endothelial cell differentiation (GO:0045603)3.48433649
41negative regulation of thymocyte apoptotic process (GO:0070244)3.46407656
42neutrophil activation involved in immune response (GO:0002283)3.45310872
43negative regulation of microtubule polymerization (GO:0031115)3.38812857
44negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.35329125
45proteasome assembly (GO:0043248)3.34838621
46macromolecular complex disassembly (GO:0032984)3.33379709
47urogenital system development (GO:0001655)3.33196546
48regulation of alternative mRNA splicing, via spliceosome (GO:0000381)3.29267390
49type B pancreatic cell proliferation (GO:0044342)3.28225799
50translational initiation (GO:0006413)3.27336004
51negative regulation of RNA splicing (GO:0033119)3.26835816
52adenosine receptor signaling pathway (GO:0001973)3.25785610
53regulation of cellular amino acid metabolic process (GO:0006521)3.20327504
54protein deneddylation (GO:0000338)3.19636708
55cullin deneddylation (GO:0010388)3.15571767
56positive regulation of RNA splicing (GO:0033120)3.14893073
57negative regulation of erythrocyte differentiation (GO:0045647)3.13723296
58pyrimidine nucleotide catabolic process (GO:0006244)3.12877586
59negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.11464299
60positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)3.07101915
61platelet dense granule organization (GO:0060155)3.05315009
62establishment of integrated proviral latency (GO:0075713)3.03272599
63positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.99930146
64phagocytosis, engulfment (GO:0006911)2.99540587
65angiogenesis involved in wound healing (GO:0060055)2.99197696
66lipoxygenase pathway (GO:0019372)2.98077877
67negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.97253624
68CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.95849899
69respiratory system process (GO:0003016)2.93864302
70platelet degranulation (GO:0002576)2.92989397
71DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.92559040
72antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.92010148
73polyamine biosynthetic process (GO:0006596)2.88644597
74positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.86357069
75nuclear-transcribed mRNA catabolic process (GO:0000956)2.86292011
76negative regulation of nitric-oxide synthase activity (GO:0051001)2.86110894
77negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.85771437
78positive regulation of receptor biosynthetic process (GO:0010870)2.85395730
79positive regulation of mitochondrial fission (GO:0090141)2.85370322
80negative regulation of ligase activity (GO:0051352)2.83639315
81negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.83639315
82regulation of response to tumor cell (GO:0002834)2.82954447
83positive regulation of response to tumor cell (GO:0002836)2.82954447
84positive regulation of immune response to tumor cell (GO:0002839)2.82954447
85regulation of immune response to tumor cell (GO:0002837)2.82954447
86negative regulation of nitric oxide biosynthetic process (GO:0045019)2.82610276
87spliceosomal snRNP assembly (GO:0000387)2.82327545
88deoxyribonucleotide catabolic process (GO:0009264)2.80256510
89intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.80219494
90signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.80219494
91mitochondrial calcium ion homeostasis (GO:0051560)2.79344463
92adenosine metabolic process (GO:0046085)2.79242561
93autophagic vacuole fusion (GO:0000046)2.79112721
94histone H2A acetylation (GO:0043968)2.78473526
95antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.77354222
96signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.76276735
97signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.76276735
98signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.76276735
99mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.76171232
100negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.75853605
101regulation of mRNA splicing, via spliceosome (GO:0048024)2.75356005
102positive regulation of Rho protein signal transduction (GO:0035025)2.74391112
103regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.74327935
104spliceosomal complex assembly (GO:0000245)2.73091469
105endothelium development (GO:0003158)2.71843094
106peptidyl-arginine modification (GO:0018195)2.70142550
107negative regulation of homotypic cell-cell adhesion (GO:0034111)2.69540154
108mRNA catabolic process (GO:0006402)2.68025930
109deoxyribose phosphate catabolic process (GO:0046386)2.65259352
110barbed-end actin filament capping (GO:0051016)2.65201056
111pinocytosis (GO:0006907)2.64534662
112membrane invagination (GO:0010324)2.63475661
113GMP metabolic process (GO:0046037)2.62361053
114signal transduction involved in DNA integrity checkpoint (GO:0072401)2.62307871
115signal transduction involved in DNA damage checkpoint (GO:0072422)2.62307871
116Arp2/3 complex-mediated actin nucleation (GO:0034314)2.62093256
117facial nerve structural organization (GO:0021612)2.62080821
118protein targeting to membrane (GO:0006612)2.61596315
119regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.60295131
120signal transduction involved in cell cycle checkpoint (GO:0072395)2.60137080
121fatty acid elongation (GO:0030497)2.59993611
122purine-containing compound salvage (GO:0043101)2.58879173
123intra-S DNA damage checkpoint (GO:0031573)2.58640477
124pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.56561417
125RNA catabolic process (GO:0006401)2.51133228
126blood vessel maturation (GO:0001955)2.50570014
127histamine secretion (GO:0001821)2.49627873
128negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.49031495
129anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.47923173
130mitochondrial fusion (GO:0008053)2.47123041
131neuron cell-cell adhesion (GO:0007158)2.46816902
132UV protection (GO:0009650)2.46457301
133positive regulation of male gonad development (GO:2000020)2.45399666
134deoxyribose phosphate metabolic process (GO:0019692)2.44581537
135regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)2.43818635
136de novo posttranslational protein folding (GO:0051084)2.43791020
137homotypic cell-cell adhesion (GO:0034109)2.42955314
138beta-amyloid metabolic process (GO:0050435)2.42799237
139pyrimidine nucleobase catabolic process (GO:0006208)2.42737010
140mRNA splice site selection (GO:0006376)2.42570835
141hydrogen peroxide catabolic process (GO:0042744)2.42417304
142mitochondrial respiratory chain complex I assembly (GO:0032981)2.41818785
143NADH dehydrogenase complex assembly (GO:0010257)2.41818785
144mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.41818785
145de novo protein folding (GO:0006458)2.41598954
146genetic imprinting (GO:0071514)2.41529532
147N-glycan processing (GO:0006491)2.40991458
148regulation of receptor recycling (GO:0001919)2.40612698
149neurofilament cytoskeleton organization (GO:0060052)2.40360340
150positive regulation of macrophage differentiation (GO:0045651)2.40132985
151pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.39543952
152positive regulation of receptor recycling (GO:0001921)2.38956083
153positive regulation of amino acid transport (GO:0051957)2.38908001
154protein-DNA complex disassembly (GO:0032986)2.38855593
155nucleosome disassembly (GO:0006337)2.38855593
156intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0008631)2.38414618
157pentose-phosphate shunt (GO:0006098)2.38176639
158layer formation in cerebral cortex (GO:0021819)2.37920684
159negative regulation of phosphoprotein phosphatase activity (GO:0032515)2.37846221
160regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.37706523
161protein complex biogenesis (GO:0070271)2.36681869
162spinal cord association neuron differentiation (GO:0021527)2.34435921
163respiratory tube development (GO:0030323)2.33815465
164cranial nerve morphogenesis (GO:0021602)2.33771162
165atrial septum morphogenesis (GO:0060413)2.33702452
166negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.33658805
167establishment of viral latency (GO:0019043)2.32327847
168negative regulation of mRNA processing (GO:0050686)2.31558083
169DNA damage response, detection of DNA damage (GO:0042769)2.31370736
170regulation of male gonad development (GO:2000018)2.26732282
171lymphoid progenitor cell differentiation (GO:0002320)2.26309621
1722-deoxyribonucleotide biosynthetic process (GO:0009265)2.24865639
173deoxyribose phosphate biosynthetic process (GO:0046385)2.24865639
174regulation of protein heterodimerization activity (GO:0043497)2.24584964
175RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.24163310
176tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.24163310
177formation of translation preinitiation complex (GO:0001731)2.24115951
178postsynaptic membrane organization (GO:0001941)2.22627616
179antigen processing and presentation via MHC class Ib (GO:0002475)2.21825178
180mitotic spindle assembly checkpoint (GO:0007094)2.20849543
181dosage compensation (GO:0007549)2.20496843
182DNA strand elongation involved in DNA replication (GO:0006271)2.20021609
183RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.19817852
184mRNA splicing, via spliceosome (GO:0000398)2.19817852
185endosome to pigment granule transport (GO:0043485)2.19259051
186endosome to melanosome transport (GO:0035646)2.19259051
187RNA splicing, via transesterification reactions (GO:0000375)2.17736977
188negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.16833476
189negative regulation of DNA-templated transcription, elongation (GO:0032785)2.16833476
190positive regulation of cell size (GO:0045793)2.15887189

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYC_18555785_ChIP-Seq_MESCs_Mouse3.84621529
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.35978908
3E2F7_22180533_ChIP-Seq_HELA_Human3.35624872
4IGF1R_20145208_ChIP-Seq_DFB_Human3.34717836
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.31476897
6TP63_19390658_ChIP-ChIP_HaCaT_Human3.26341705
7HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.10993640
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.94939017
9SRF_21415370_ChIP-Seq_HL-1_Mouse2.48535477
10TTF2_22483619_ChIP-Seq_HELA_Human2.47677185
11CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.40748255
12NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.37925963
13ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.30829760
14XRN2_22483619_ChIP-Seq_HELA_Human2.27477032
15MYC_19079543_ChIP-ChIP_MESCs_Mouse2.24156002
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.22001674
17MYC_22102868_ChIP-Seq_BL_Human2.21093562
18HOXB4_20404135_ChIP-ChIP_EML_Mouse2.15940257
19EZH2_27304074_Chip-Seq_ESCs_Mouse2.13973128
20SRY_22984422_ChIP-ChIP_TESTIS_Rat2.13712715
21ELF1_17652178_ChIP-ChIP_JURKAT_Human2.13298947
22CIITA_25753668_ChIP-Seq_RAJI_Human2.11772870
23DMRT1_21621532_ChIP-ChIP_FETAL_Ovary2.10340211
24ATF3_23680149_ChIP-Seq_GBM1-GSC_Human2.09709393
25SCL_19346495_ChIP-Seq_HPC-7_Human2.09150634
26RARG_19884340_ChIP-ChIP_MEFs_Mouse2.07197537
27LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.05931034
28RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.05442330
29MYC_18358816_ChIP-ChIP_MESCs_Mouse2.05415266
30TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.04292074
31MYC_19030024_ChIP-ChIP_MESCs_Mouse2.00723348
32ZNF274_21170338_ChIP-Seq_K562_Hela1.99554762
33RBPJ_22232070_ChIP-Seq_NCS_Mouse1.97214319
34CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.96336056
35HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.94726140
36EST1_17652178_ChIP-ChIP_JURKAT_Human1.89862703
37ZFP281_18757296_ChIP-ChIP_E14_Mouse1.88158002
38IKZF1_21737484_ChIP-ChIP_HCT116_Human1.84664745
39EZH2_22144423_ChIP-Seq_EOC_Human1.84426521
40CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.83361397
41KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.81870950
42PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.80454046
43JARID2_20064375_ChIP-Seq_MESCs_Mouse1.77418368
44* IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.76299351
45PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.76008462
46ETS1_20019798_ChIP-Seq_JURKAT_Human1.75323836
47PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.70455503
48HIF1A_21447827_ChIP-Seq_MCF-7_Human1.69023969
49SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.68346260
50GABP_17652178_ChIP-ChIP_JURKAT_Human1.67858090
51NELFA_20434984_ChIP-Seq_ESCs_Mouse1.67451016
52DCP1A_22483619_ChIP-Seq_HELA_Human1.66137833
53CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.66044425
54MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.65926229
55HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.65525163
56ZFX_18555785_ChIP-Seq_MESCs_Mouse1.62353938
57JARID2_20075857_ChIP-Seq_MESCs_Mouse1.57513447
58MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.57063484
59TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.56271163
60LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.56257358
61CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.55318239
62POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.53002758
63TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.49947568
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.49200332
65YY1_21170310_ChIP-Seq_MESCs_Mouse1.45737182
66FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.44076414
67TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.43426391
68TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.42581753
69CBX2_27304074_Chip-Seq_ESCs_Mouse1.42209247
70CLOCK_20551151_ChIP-Seq_293T_Human1.41910918
71ZNF263_19887448_ChIP-Seq_K562_Human1.41151021
72IRF8_21731497_ChIP-ChIP_J774_Mouse1.40416371
73MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.39482409
74WT1_19549856_ChIP-ChIP_CCG9911_Human1.39413195
75E2F4_17652178_ChIP-ChIP_JURKAT_Human1.38792002
76* TFEB_21752829_ChIP-Seq_HELA_Human1.36562222
77E2F1_18555785_ChIP-Seq_MESCs_Mouse1.35995081
78SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.35408634
79THAP11_20581084_ChIP-Seq_MESCs_Mouse1.35348358
80VDR_23849224_ChIP-Seq_CD4+_Human1.34549053
81GABP_19822575_ChIP-Seq_HepG2_Human1.34217317
82BMI1_23680149_ChIP-Seq_NPCS_Mouse1.33876051
83RNF2_27304074_Chip-Seq_NSC_Mouse1.33620836
84CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.33250636
85ERG_20887958_ChIP-Seq_HPC-7_Mouse1.32893163
86E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.32473428
87CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.32266930
88TP53_20018659_ChIP-ChIP_R1E_Mouse1.31734964
89MYB_21317192_ChIP-Seq_ERMYB_Mouse1.31538440
90PADI4_21655091_ChIP-ChIP_MCF-7_Human1.31066174
91STAT4_19710469_ChIP-ChIP_TH1__Mouse1.30451715
92CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.29907228
93OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.29664787
94TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.28911238
95EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.28802418
96SPI1_23547873_ChIP-Seq_NB4_Human1.28366069
97JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.28135173
98STAT6_21828071_ChIP-Seq_BEAS2B_Human1.27607896
99YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26856513
100KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.25657466
101SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.25215351
102PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24560977
103ELK3_25401928_ChIP-Seq_HUVEC_Human1.23718516
104TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.23031467
105SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.22187506
106EED_16625203_ChIP-ChIP_MESCs_Mouse1.22137238
107VDR_21846776_ChIP-Seq_THP-1_Human1.21978265
108FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.21475911
109EWS_26573619_Chip-Seq_HEK293_Human1.21033840
110NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.20614660
111MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.19864973
112BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.19475489
113ELK1_22589737_ChIP-Seq_MCF10A_Human1.18430528
114FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.16768144
115NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.16410840
116SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.16086433
117GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.15750792
118GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.15129430
119SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.14016138
120FOXP3_21729870_ChIP-Seq_TREG_Human1.13153398
121RNF2_27304074_Chip-Seq_ESCs_Mouse1.12904290
122WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.12741125
123SOX17_20123909_ChIP-Seq_XEN_Mouse1.12562695
124EZH2_18974828_ChIP-Seq_MESCs_Mouse1.11937996
125RNF2_18974828_ChIP-Seq_MESCs_Mouse1.11937996
126GATA2_21666600_ChIP-Seq_HMVEC_Human1.11793386
127SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.09927669
128CTCF_18555785_ChIP-Seq_MESCs_Mouse1.09305840
129* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.07421541
130RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.07323512
131GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07146197
132DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.06384161
133RING1B_27294783_Chip-Seq_ESCs_Mouse1.06370098
134ELK1_19687146_ChIP-ChIP_HELA_Human1.05589923
135DNAJC2_21179169_ChIP-ChIP_NT2_Human1.05482018
136POU5F1_16153702_ChIP-ChIP_HESCs_Human1.05220913
137TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.04754208
138IRF8_22096565_ChIP-ChIP_GC-B_Human1.04733578
139BRD4_25478319_ChIP-Seq_HGPS_Human1.04660516
140SUZ12_27294783_Chip-Seq_ESCs_Mouse1.04551341
141NANOG_18555785_ChIP-Seq_MESCs_Mouse1.04388627
142EZH2_27294783_Chip-Seq_ESCs_Mouse1.04325520
143CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.03586989
144GATA4_21415370_ChIP-Seq_HL-1_Mouse1.03264911
145ZFP281_27345836_Chip-Seq_ESCs_Mouse1.02852806
146TRIM28_21343339_ChIP-Seq_HEK293_Human1.01854816
147SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00396407
148CREB1_15753290_ChIP-ChIP_HEK293T_Human0.99998934
149FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99943009
150SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.98913004
151NOTCH1_21737748_ChIP-Seq_TLL_Human0.98833912
152ESR1_15608294_ChIP-ChIP_MCF-7_Human0.98237890
153STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.97685439
154JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97334015
155NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.94109489

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003122_maternal_imprinting6.15991040
2MP0005464_abnormal_platelet_physiology4.73271326
3MP0003121_genomic_imprinting3.68610011
4MP0005058_abnormal_lysosome_morphology3.21499151
5MP0006276_abnormal_autonomic_nervous3.10598736
6MP0000372_irregular_coat_pigmentation2.90951862
7MP0003123_paternal_imprinting2.90451384
8MP0009379_abnormal_foot_pigmentation2.89357145
9MP0003566_abnormal_cell_adhesion2.55369213
10MP0003385_abnormal_body_wall2.24906997
11MP0005257_abnormal_intraocular_pressure2.21436142
12MP0005275_abnormal_skin_tensile2.13152168
13MP0003186_abnormal_redox_activity2.12677322
14MP0002938_white_spotting2.09687359
15MP0005645_abnormal_hypothalamus_physiol2.03449358
16MP0009384_cardiac_valve_regurgitation1.98114793
17MP0006054_spinal_hemorrhage1.94714831
18MP0000343_altered_response_to1.93998576
19MP0003724_increased_susceptibility_to1.87799421
20MP0003942_abnormal_urinary_system1.86583879
21MP0005423_abnormal_somatic_nervous1.86551651
22MP0005083_abnormal_biliary_tract1.86178628
23MP0001542_abnormal_bone_strength1.79444028
24MP0005084_abnormal_gallbladder_morpholo1.69874567
25MP0000631_abnormal_neuroendocrine_gland1.68048738
26MP0008004_abnormal_stomach_pH1.66603449
27MP0004808_abnormal_hematopoietic_stem1.64047633
28MP0003787_abnormal_imprinting1.63711262
29MP0000049_abnormal_middle_ear1.62917486
30MP0003119_abnormal_digestive_system1.62626834
31MP0002249_abnormal_larynx_morphology1.59295386
32MP0010030_abnormal_orbit_morphology1.57592079
33MP0008438_abnormal_cutaneous_collagen1.56859434
34MP0008789_abnormal_olfactory_epithelium1.55466876
35MP0003828_pulmonary_edema1.53553500
36MP0002282_abnormal_trachea_morphology1.50856828
37MP0000534_abnormal_ureter_morphology1.50575649
38MP0006292_abnormal_olfactory_placode1.50314842
39MP0003136_yellow_coat_color1.49837860
40MP0005165_increased_susceptibility_to1.48500214
41MP0000537_abnormal_urethra_morphology1.46611169
42MP0002396_abnormal_hematopoietic_system1.46396665
43MP0009250_abnormal_appendicular_skeleto1.43213128
44MP0001958_emphysema1.42938648
45MP0003115_abnormal_respiratory_system1.42766747
46MP0001879_abnormal_lymphatic_vessel1.40647713
47MP0002184_abnormal_innervation1.39560470
48MP0005171_absent_coat_pigmentation1.38593480
49MP0003950_abnormal_plasma_membrane1.33956172
50MP0005390_skeleton_phenotype1.33913033
51MP0000751_myopathy1.33302861
52MP0002148_abnormal_hypersensitivity_rea1.30122541
53MP0005367_renal/urinary_system_phenotyp1.30002641
54MP0000516_abnormal_urinary_system1.30002641
55MP0005394_taste/olfaction_phenotype1.29057160
56MP0005499_abnormal_olfactory_system1.29057160
57MP0002751_abnormal_autonomic_nervous1.28812270
58MP0001533_abnormal_skeleton_physiology1.28655263
59MP0004084_abnormal_cardiac_muscle1.28596104
60MP0000569_abnormal_digit_pigmentation1.28416900
61MP0003941_abnormal_skin_development1.27536282
62MP0003880_abnormal_central_pattern1.26682950
63MP0001968_abnormal_touch/_nociception1.25727817
64MP0002102_abnormal_ear_morphology1.25506046
65MP0003567_abnormal_fetal_cardiomyocyte1.23665108
66MP0005503_abnormal_tendon_morphology1.21147780
67MP0002736_abnormal_nociception_after1.20993672
68MP0008007_abnormal_cellular_replicative1.18112598
69MP0000778_abnormal_nervous_system1.17621502
70MP0008260_abnormal_autophagy1.17255603
71MP0002295_abnormal_pulmonary_circulatio1.16407393
72MP0000358_abnormal_cell_content/1.14610750
73MP0002932_abnormal_joint_morphology1.14233239
74MP0003303_peritoneal_inflammation1.14128699
75MP0004510_myositis1.11563542
76MP0002233_abnormal_nose_morphology1.11381613
77MP0000955_abnormal_spinal_cord1.09872246
78MP0008995_early_reproductive_senescence1.08949910
79MP0002638_abnormal_pupillary_reflex1.08237639
80MP0010368_abnormal_lymphatic_system1.08215143
81MP0002733_abnormal_thermal_nociception1.07939234
82MP0002557_abnormal_social/conspecific_i1.06651300
83MP0000428_abnormal_craniofacial_morphol1.05884981
84MP0002177_abnormal_outer_ear1.05590449
85MP0001299_abnormal_eye_distance/1.05560365
86MP0000678_abnormal_parathyroid_gland1.04001064
87MP0003861_abnormal_nervous_system1.02785111
88MP0001188_hyperpigmentation1.02727146
89MP0001243_abnormal_dermal_layer1.02350406
90MP0003191_abnormal_cellular_cholesterol1.01933126
91MP0002081_perinatal_lethality1.00870815
92MP0002114_abnormal_axial_skeleton1.00292348
93MP0001348_abnormal_lacrimal_gland0.96962051
94MP0004811_abnormal_neuron_physiology0.96615174
95MP0000750_abnormal_muscle_regeneration0.96384589
96MP0001986_abnormal_taste_sensitivity0.95755320
97MP0008775_abnormal_heart_ventricle0.95424006
98MP0002116_abnormal_craniofacial_bone0.95286553
99MP0003315_abnormal_perineum_morphology0.94997288
100MP0003279_aneurysm0.94636027
101MP0005023_abnormal_wound_healing0.94420106
102MP0009840_abnormal_foam_cell0.94398772
103MP0009780_abnormal_chondrocyte_physiolo0.94048030
104MP0003943_abnormal_hepatobiliary_system0.91053096
105MP0005187_abnormal_penis_morphology0.90131169
106MP0003890_abnormal_embryonic-extraembry0.89783497
107MP0003795_abnormal_bone_structure0.89349023
108MP0001835_abnormal_antigen_presentation0.88351646
109MP0004272_abnormal_basement_membrane0.88129542
110MP0009763_increased_sensitivity_to0.87674672
111MP0003755_abnormal_palate_morphology0.86482821
112MP0003935_abnormal_craniofacial_develop0.86406849
113MP0004145_abnormal_muscle_electrophysio0.86356919
114MP0002234_abnormal_pharynx_morphology0.85354578
115MP0000685_abnormal_immune_system0.85027657
116MP0001851_eye_inflammation0.84518936
117MP0000767_abnormal_smooth_muscle0.84006986
118MP0003635_abnormal_synaptic_transmissio0.83383964
119MP0004134_abnormal_chest_morphology0.83324909
120MP0000639_abnormal_adrenal_gland0.83234418
121MP0000749_muscle_degeneration0.83165256
122MP0005000_abnormal_immune_tolerance0.83104175
123MP0000858_altered_metastatic_potential0.82904359
124MP0005075_abnormal_melanosome_morpholog0.82013618
125MP0001293_anophthalmia0.80759176
126MP0000249_abnormal_blood_vessel0.80525475
127MP0009053_abnormal_anal_canal0.80289476
128MP0000230_abnormal_systemic_arterial0.80257402
129MP0004859_abnormal_synaptic_plasticity0.79858655
130MP0005408_hypopigmentation0.79601953
131MP0001849_ear_inflammation0.79176001
132MP0005508_abnormal_skeleton_morphology0.78950582
133MP0003656_abnormal_erythrocyte_physiolo0.78682601
134MP0002734_abnormal_mechanical_nocicepti0.78198603
135MP0004858_abnormal_nervous_system0.77162059
136MP0000681_abnormal_thyroid_gland0.77142962
137MP0002095_abnormal_skin_pigmentation0.77115400
138MP0005174_abnormal_tail_pigmentation0.76886592
139MP0008932_abnormal_embryonic_tissue0.76252001
140MP0002128_abnormal_blood_circulation0.76137776
141MP0003693_abnormal_embryo_hatching0.75509777
142MP0008877_abnormal_DNA_methylation0.75253996
143MP0002152_abnormal_brain_morphology0.74739601
144MP0004133_heterotaxia0.74609359
145MP0003705_abnormal_hypodermis_morpholog0.74000504
146MP0001853_heart_inflammation0.73636817
147MP0005397_hematopoietic_system_phenotyp0.73362073
148MP0001545_abnormal_hematopoietic_system0.73362073
149MP0003638_abnormal_response/metabolism_0.72912558
150MP0000383_abnormal_hair_follicle0.72844089
151MP0003077_abnormal_cell_cycle0.72736709
152MP0002896_abnormal_bone_mineralization0.72707067
153MP0002132_abnormal_respiratory_system0.70170862
154MP0004270_analgesia0.70040946
155MP0005164_abnormal_response_to0.69648797
156MP0000163_abnormal_cartilage_morphology0.69645763
157MP0005193_abnormal_anterior_eye0.69304948
158MP0005595_abnormal_vascular_smooth0.69051895
159MP0004883_abnormal_blood_vessel0.68772158
160MP0001529_abnormal_vocalization0.68110552
161MP0002085_abnormal_embryonic_tissue0.67832676
162MP0002113_abnormal_skeleton_development0.66316585
163MP0002089_abnormal_postnatal_growth/wei0.66151525
164MP0002109_abnormal_limb_morphology0.66050488
165MP0000613_abnormal_salivary_gland0.65513431
166MP0009697_abnormal_copulation0.65470608
167MP0000465_gastrointestinal_hemorrhage0.65431020
168MP0009333_abnormal_splenocyte_physiolog0.65373144
169MP0002090_abnormal_vision0.65365876
170MP0006082_CNS_inflammation0.64987657
171MP0005248_abnormal_Harderian_gland0.64878962

Predicted human phenotypes

RankGene SetZ-score
1Petechiae (HP:0000967)5.74128773
2Prolonged bleeding time (HP:0003010)5.11239475
3Increased mean platelet volume (HP:0011877)4.99054753
4Menorrhagia (HP:0000132)4.89943291
5Abnormal platelet volume (HP:0011876)4.59339638
6Purpura (HP:0000979)4.45304006
7Premature rupture of membranes (HP:0001788)4.27713387
8Short 4th metacarpal (HP:0010044)3.89887827
9Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.89887827
10Epistaxis (HP:0000421)3.86390988
11Hepatosplenomegaly (HP:0001433)3.50799282
12Agitation (HP:0000713)3.49023854
13Renal duplication (HP:0000075)3.36314749
14Colon cancer (HP:0003003)3.34341619
15Syringomyelia (HP:0003396)3.28139656
16Spinal cord lesions (HP:0100561)3.28139656
17Aplastic anemia (HP:0001915)3.20930377
18Vertebral compression fractures (HP:0002953)3.17642016
19Cervical subluxation (HP:0003308)3.15922553
20Abnormality of the 4th metacarpal (HP:0010012)3.12283795
21Gingival bleeding (HP:0000225)3.06333532
22Sleep apnea (HP:0010535)3.06014231
23Upper limb muscle weakness (HP:0003484)3.02259465
24Failure to thrive in infancy (HP:0001531)2.87153006
25Hyperacusis (HP:0010780)2.86220805
26Abnormality of cells of the erythroid lineage (HP:0012130)2.86136045
27Renal Fanconi syndrome (HP:0001994)2.85895049
283-Methylglutaconic aciduria (HP:0003535)2.79427721
29Aortic dissection (HP:0002647)2.78965757
30Abnormal hair whorl (HP:0010721)2.77772890
31Hepatoblastoma (HP:0002884)2.76392024
32Abnormality of the heme biosynthetic pathway (HP:0010472)2.75068720
33Impaired platelet aggregation (HP:0003540)2.70770160
34Abnormal platelet function (HP:0011869)2.70770160
35Abnormality of the parietal bone (HP:0002696)2.64303495
36Limb dystonia (HP:0002451)2.63671357
37Microglossia (HP:0000171)2.63510496
38Vacuolated lymphocytes (HP:0001922)2.62456643
39Morphological abnormality of the middle ear (HP:0008609)2.61322553
40Severe visual impairment (HP:0001141)2.60244778
41Abnormal pupillary function (HP:0007686)2.58529544
42Shawl scrotum (HP:0000049)2.56983196
43Dysostosis multiplex (HP:0000943)2.56963378
44Abnormal number of erythroid precursors (HP:0012131)2.56744851
45Increased IgM level (HP:0003496)2.55700888
46Type 2 muscle fiber atrophy (HP:0003554)2.54409843
47Abnormal number of incisors (HP:0011064)2.54264252
48Osteolytic defects of the hand bones (HP:0009699)2.52832950
49Osteolytic defects of the phalanges of the hand (HP:0009771)2.52832950
50Muscle fiber atrophy (HP:0100295)2.50838808
51Acute lymphatic leukemia (HP:0006721)2.48387547
52Hyperlipoproteinemia (HP:0010980)2.47769696
53Nausea (HP:0002018)2.43247530
54Flat cornea (HP:0007720)2.42242011
55Lissencephaly (HP:0001339)2.41124741
56Thrombocytosis (HP:0001894)2.38917297
57Cholecystitis (HP:0001082)2.38692098
58Abnormal gallbladder physiology (HP:0012438)2.38692098
59Protrusio acetabuli (HP:0003179)2.35155013
60Loss of speech (HP:0002371)2.33170038
61Exertional dyspnea (HP:0002875)2.32279157
62Spinal rigidity (HP:0003306)2.30054184
63Down-sloping shoulders (HP:0200021)2.29455793
64Abnormality of dentin (HP:0010299)2.28304190
65Abnormality of glycolipid metabolism (HP:0010969)2.28236656
66Abnormality of liposaccharide metabolism (HP:0010968)2.28236656
67Abnormality of glycosphingolipid metabolism (HP:0004343)2.28236656
68Bowel diverticulosis (HP:0005222)2.27931531
69Abnormality of lateral ventricle (HP:0030047)2.24557627
70Septo-optic dysplasia (HP:0100842)2.22843255
71Abnormality of skull ossification (HP:0002703)2.22808064
72High anterior hairline (HP:0009890)2.22165649
73Joint stiffness (HP:0001387)2.20593751
74Follicular hyperkeratosis (HP:0007502)2.20316239
75Acute necrotizing encephalopathy (HP:0006965)2.17191035
76Shoulder girdle muscle weakness (HP:0003547)2.16694413
77Overriding aorta (HP:0002623)2.14227705
78Aortic aneurysm (HP:0004942)2.14193879
79Medulloblastoma (HP:0002885)2.13147914
80Hypoventilation (HP:0002791)2.11381659
81Centrally nucleated skeletal muscle fibers (HP:0003687)2.11341822
82Abnormal mitochondria in muscle tissue (HP:0008316)2.10965133
83Abnormal auditory evoked potentials (HP:0006958)2.07178014
84Soft skin (HP:0000977)2.05943647
85Reticulocytopenia (HP:0001896)2.05668925
86Sacral dimple (HP:0000960)2.04588360
87Abnormality of the umbilical cord (HP:0010881)2.03835396
88Pallor (HP:0000980)2.02919120
89Abnormality of the anterior horn cell (HP:0006802)2.02826629
90Degeneration of anterior horn cells (HP:0002398)2.02826629
91Renovascular hypertension (HP:0100817)2.02355953
92Dyschromatopsia (HP:0007641)2.00306663
93Aplasia/Hypoplasia of the brainstem (HP:0007362)2.00294287
94Hypoplasia of the brainstem (HP:0002365)2.00294287
95Midline defect of the nose (HP:0004122)2.00017922
96Adducted thumb (HP:0001181)1.99791752
97Renal dysplasia (HP:0000110)1.98716760
98Spondylolisthesis (HP:0003302)1.98268805
99Vascular tortuosity (HP:0004948)1.98194862
100Insomnia (HP:0100785)1.97197758
101Tetraparesis (HP:0002273)1.96337453
102Growth hormone deficiency (HP:0000824)1.95030808
103Abnormality of the vasculature of the conjunctiva (HP:0008054)1.94830279
104Asymmetry of the thorax (HP:0001555)1.94754658
105Short middle phalanx of the 5th finger (HP:0004220)1.94421339
106Bruising susceptibility (HP:0000978)1.92980271
107Mitochondrial inheritance (HP:0001427)1.92716002
108Acute encephalopathy (HP:0006846)1.92200376
109Neoplasm of the heart (HP:0100544)1.91685089
110Bladder diverticulum (HP:0000015)1.89810662
111Elfin facies (HP:0004428)1.89788220
112Conjunctival telangiectasia (HP:0000524)1.89733253
113Hypothermia (HP:0002045)1.89211383
114Abnormality of skeletal muscle fiber size (HP:0012084)1.88975678
115Abnormal delivery (HP:0001787)1.88524707
116Restlessness (HP:0000711)1.87974525
117Anterior segment dysgenesis (HP:0007700)1.86417434
118Optic nerve coloboma (HP:0000588)1.85024008
119Atrophy/Degeneration involving motor neurons (HP:0007373)1.83473476
120Distal lower limb muscle weakness (HP:0009053)1.83162984
121Large eyes (HP:0001090)1.81301517
122Rimmed vacuoles (HP:0003805)1.81105449
123Abnormality of the nasolacrimal system (HP:0000614)1.80920972
124Hepatic necrosis (HP:0002605)1.80723862
125Abnormality of the columella (HP:0009929)1.80620696
126Arterial tortuosity (HP:0005116)1.80559197
127Hepatocellular necrosis (HP:0001404)1.79169705
128Distal lower limb amyotrophy (HP:0008944)1.76273615
129Prolonged neonatal jaundice (HP:0006579)1.75397091
130Poor eye contact (HP:0000817)1.75150950
131Dilatation of the ascending aorta (HP:0005111)1.73718585
132Back pain (HP:0003418)1.72021203
133Abnormality of placental membranes (HP:0011409)1.71949096
134Amniotic constriction ring (HP:0009775)1.71949096
135Broad alveolar ridges (HP:0000187)1.71408856
136Cutaneous melanoma (HP:0012056)1.71177175
137Pointed chin (HP:0000307)1.71139250
138Neoplasm of the peripheral nervous system (HP:0100007)1.71036485
139Ankle clonus (HP:0011448)1.70736948
140Abnormality of the lacrimal duct (HP:0011481)1.70403889
141Wormian bones (HP:0002645)1.70188057
142Diastasis recti (HP:0001540)1.69921857
143Type I transferrin isoform profile (HP:0003642)1.68433993
144Flared iliac wings (HP:0002869)1.68409297
145Nonimmune hydrops fetalis (HP:0001790)1.68320597
146Ankle contracture (HP:0006466)1.67966385
147Broad toe (HP:0001837)1.67893950
148Increased hepatocellular lipid droplets (HP:0006565)1.67221198
149Increased intramyocellular lipid droplets (HP:0012240)1.66742312
150Broad finger (HP:0001500)1.66307290
151Abnormality of the aortic arch (HP:0012303)1.66087507
152Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.65992661
153Easy fatigability (HP:0003388)1.65975442
154Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.65828093
155Increased variability in muscle fiber diameter (HP:0003557)1.65453103
156Poor head control (HP:0002421)1.64553296
157Downturned corners of mouth (HP:0002714)1.64307177
158Generalized aminoaciduria (HP:0002909)1.63314752
159Bifid tongue (HP:0010297)1.63046386
160Abnormalities of placenta or umbilical cord (HP:0001194)1.62941753
161Obsessive-compulsive behavior (HP:0000722)1.62611604
162Breech presentation (HP:0001623)1.61298898
163Abnormality of the musculature of the pelvis (HP:0001469)1.61168953
164Abnormality of the hip-girdle musculature (HP:0001445)1.61168953
165Blue sclerae (HP:0000592)1.60877977
166Megalocornea (HP:0000485)1.60588663
16711 pairs of ribs (HP:0000878)1.60168318
168Decreased skull ossification (HP:0004331)1.60079637
169Papillary thyroid carcinoma (HP:0002895)1.59957252
170Pelvic girdle muscle weakness (HP:0003749)1.59496463
171Weak cry (HP:0001612)1.59353012
172Abnormality of the phalanges of the hallux (HP:0010057)1.58756750
173Hypoplastic heart (HP:0001961)1.58676711
174Abnormality of the metopic suture (HP:0005556)1.58492007
175Amaurosis fugax (HP:0100576)1.58410378
176Progressive macrocephaly (HP:0004481)1.58336374
177Periauricular skin pits (HP:0100277)1.58234652
178Preauricular pit (HP:0004467)1.58234652
179Generalized amyotrophy (HP:0003700)1.57691652
180Popliteal pterygium (HP:0009756)1.57309024
181Ependymoma (HP:0002888)1.55408997
182Hypoplastic left heart (HP:0004383)1.54895594
183Obstructive sleep apnea (HP:0002870)1.53187020
184Visual hallucinations (HP:0002367)1.52989292
185Increased density of long bones (HP:0006392)1.52835720
186Poor suck (HP:0002033)1.52474167
187Wide cranial sutures (HP:0010537)1.52316954
188Exotropia (HP:0000577)1.52201889

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.39238331
2TESK13.13777197
3WNK33.07941971
4ERBB33.04255153
5FLT32.91277037
6MARK12.90878522
7MKNK12.74890239
8BCKDK2.73314995
9PIM22.64599029
10MST42.64459986
11MAPK132.50923189
12UHMK12.46369332
13TESK22.42791077
14TGFBR12.33653350
15TIE12.31655675
16CDC72.31574896
17DYRK22.13128716
18EPHB22.09256214
19CDK192.06583081
20TRIM282.05136767
21EIF2AK11.99154160
22BCR1.98237027
23CSNK1G31.83025086
24NUAK11.80593174
25DYRK31.75383216
26PASK1.73941968
27TNIK1.72201895
28SIK21.71141790
29PDGFRA1.70665415
30NTRK21.70391493
31EEF2K1.64035952
32MAP3K121.63492560
33VRK11.58283806
34MINK11.54645276
35MAP3K101.54590980
36MKNK21.49602410
37LIMK11.47073648
38SCYL21.46640553
39ACVR1B1.41125388
40TAF11.39527297
41BMX1.38076719
42DDR21.35490621
43DAPK31.32580406
44ILK1.32540533
45KIT1.23830633
46GRK51.23379486
47CSNK1A1L1.22305314
48PAK41.18781002
49NTRK31.17364802
50KDR1.16072884
51CCNB11.14391666
52TSSK61.13679855
53JAK31.12557646
54CSNK1G21.10840301
55MAP4K21.10524259
56CSF1R1.10224332
57CSNK1G11.10037073
58NME21.09125261
59NEK91.03005968
60MAP2K71.02037807
61BUB11.00397425
62SRPK11.00357478
63TAOK20.99055493
64MAP3K50.98516618
65FES0.97235479
66MAPKAPK30.95094487
67ARAF0.95047511
68WEE10.93683119
69GRK70.92745616
70NEK20.90425044
71CAMKK20.89716200
72MAP3K30.87774839
73PTK2B0.87658476
74ADRBK20.84789658
75IRAK30.82718180
76SMG10.81009904
77RPS6KB20.80361323
78EIF2AK30.80214320
79BRSK20.78307595
80ABL20.76387479
81TBK10.75882216
82RIPK10.74956120
83HIPK20.74745026
84TGFBR20.74364463
85MUSK0.74056014
86CDK80.73237967
87BTK0.72891956
88FER0.72158353
89PAK10.72054890
90CAMK40.70258597
91PAK20.69519813
92MAPK90.69406350
93IKBKB0.67913138
94STK160.67497839
95AURKA0.67365744
96ADRBK10.65906701
97PKN20.64682777
98CDK140.63920758
99SIK30.63216202
100MAPKAPK50.63016302
101MOS0.58844366
102PIK3CG0.58679110
103STK40.57998941
104ATR0.57960631
105BRSK10.57881892
106PLK30.57390846
107DYRK1B0.56072552
108ROCK20.56051983
109CDK70.55477509
110NTRK10.54448202
111EIF2AK20.54140695
112BMPR20.53580345
113TAOK30.52773414
114NEK10.51827076
115CDK180.51097581
116ZAP700.50947349
117CDK11A0.48980347
118DYRK1A0.48934617
119RET0.48206898
120CDK150.47258844
121MAP2K20.46999058
122ICK0.46924060
123TEC0.45826748
124MYLK0.45438297
125CSNK2A20.45117885
126CDK50.44895093
127CLK10.43060099
128CDK20.42819041
129CHUK0.42474391
130LRRK20.41370522
131DAPK10.41024284
132PLK10.40818700
133ERBB20.40747880
134LYN0.40698618
135MAP2K60.40631550
136HCK0.40380047
137MAPK40.40026670
138MAP3K110.39277101
139FGR0.39027518
140RPS6KA50.38650334
141SYK0.38503045
142MAPK80.37986328
143PRKD10.37884132
144PBK0.37732798
145EPHB10.37441059
146ZAK0.37288531
147AKT10.37206715
148CASK0.36824073
149PHKG20.36605902
150PHKG10.36605902
151STK100.35844745
152CAMK10.35159937
153GSK3A0.33896260
154BMPR1B0.33800701

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.96943162
2Fatty acid elongation_Homo sapiens_hsa000623.19928567
3Spliceosome_Homo sapiens_hsa030403.06148817
4DNA replication_Homo sapiens_hsa030302.94585036
5Mismatch repair_Homo sapiens_hsa034302.58711503
6SNARE interactions in vesicular transport_Homo sapiens_hsa041302.39088528
7Glycosaminoglycan degradation_Homo sapiens_hsa005312.17449246
8Glutathione metabolism_Homo sapiens_hsa004802.04587759
9Base excision repair_Homo sapiens_hsa034101.93380849
10Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.82310777
11Cell cycle_Homo sapiens_hsa041101.79189544
12ECM-receptor interaction_Homo sapiens_hsa045121.76108267
13Proteasome_Homo sapiens_hsa030501.69684607
14Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.61697195
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.60723028
16N-Glycan biosynthesis_Homo sapiens_hsa005101.59263710
17Other glycan degradation_Homo sapiens_hsa005111.58830222
18Nucleotide excision repair_Homo sapiens_hsa034201.49841268
19Lysosome_Homo sapiens_hsa041421.39327196
20Steroid biosynthesis_Homo sapiens_hsa001001.35467439
21Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.32409579
22Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.31980936
23RNA transport_Homo sapiens_hsa030131.31390370
24Pyrimidine metabolism_Homo sapiens_hsa002401.31163017
25Pentose phosphate pathway_Homo sapiens_hsa000301.29693000
26Notch signaling pathway_Homo sapiens_hsa043301.26368134
27RNA degradation_Homo sapiens_hsa030181.25950887
28Parkinsons disease_Homo sapiens_hsa050121.24495893
29Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.20910498
30Basal cell carcinoma_Homo sapiens_hsa052171.20827915
31Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.20640281
32Collecting duct acid secretion_Homo sapiens_hsa049661.18448448
33Hedgehog signaling pathway_Homo sapiens_hsa043401.15996870
34mRNA surveillance pathway_Homo sapiens_hsa030151.14737894
35Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.14021583
36Colorectal cancer_Homo sapiens_hsa052101.12829916
37Protein export_Homo sapiens_hsa030601.12321016
38Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.12086102
39Cocaine addiction_Homo sapiens_hsa050301.11612762
40Gap junction_Homo sapiens_hsa045401.11576177
41Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.10850844
42Allograft rejection_Homo sapiens_hsa053301.10662629
43Transcriptional misregulation in cancer_Homo sapiens_hsa052021.09537845
44Axon guidance_Homo sapiens_hsa043601.07720724
45Basal transcription factors_Homo sapiens_hsa030221.07561747
462-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.06646654
47Alcoholism_Homo sapiens_hsa050341.06371539
48Phagosome_Homo sapiens_hsa041451.05911081
49Oocyte meiosis_Homo sapiens_hsa041141.03392967
50Wnt signaling pathway_Homo sapiens_hsa043101.02503600
51Rheumatoid arthritis_Homo sapiens_hsa053231.01600588
52Thyroid cancer_Homo sapiens_hsa052161.01517552
53TGF-beta signaling pathway_Homo sapiens_hsa043501.00144483
54Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.97839176
55Neurotrophin signaling pathway_Homo sapiens_hsa047220.95872848
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.95753090
57Autoimmune thyroid disease_Homo sapiens_hsa053200.94492147
58Biosynthesis of amino acids_Homo sapiens_hsa012300.94487698
59Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.93848907
60Dopaminergic synapse_Homo sapiens_hsa047280.92872068
61Epstein-Barr virus infection_Homo sapiens_hsa051690.91245734
62Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.90788145
63Asthma_Homo sapiens_hsa053100.90696912
64Huntingtons disease_Homo sapiens_hsa050160.88699933
65p53 signaling pathway_Homo sapiens_hsa041150.87480920
66HTLV-I infection_Homo sapiens_hsa051660.86948465
67RNA polymerase_Homo sapiens_hsa030200.86457580
68Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.86400706
69Nicotine addiction_Homo sapiens_hsa050330.85672015
70Homologous recombination_Homo sapiens_hsa034400.85604810
71Focal adhesion_Homo sapiens_hsa045100.84796474
72Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.84556803
73Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.83372640
74Hematopoietic cell lineage_Homo sapiens_hsa046400.81356987
75Salmonella infection_Homo sapiens_hsa051320.81232987
76Melanogenesis_Homo sapiens_hsa049160.80975935
77Carbon metabolism_Homo sapiens_hsa012000.80478064
78Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.80315601
79Galactose metabolism_Homo sapiens_hsa000520.79277012
80Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.79209829
81MicroRNAs in cancer_Homo sapiens_hsa052060.79028305
82Sulfur metabolism_Homo sapiens_hsa009200.78768049
83Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.78679742
84Graft-versus-host disease_Homo sapiens_hsa053320.78650331
85Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.78208210
86Endocytosis_Homo sapiens_hsa041440.78097567
87Serotonergic synapse_Homo sapiens_hsa047260.77296799
88Hippo signaling pathway_Homo sapiens_hsa043900.76968748
89Pathways in cancer_Homo sapiens_hsa052000.74763909
90Purine metabolism_Homo sapiens_hsa002300.74460370
91Chronic myeloid leukemia_Homo sapiens_hsa052200.74384613
92Non-homologous end-joining_Homo sapiens_hsa034500.74329902
93Long-term potentiation_Homo sapiens_hsa047200.74181943
94Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.73382181
95Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.73168135
96Herpes simplex infection_Homo sapiens_hsa051680.73113252
97Systemic lupus erythematosus_Homo sapiens_hsa053220.72631809
98Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.72265302
99Maturity onset diabetes of the young_Homo sapiens_hsa049500.71388820
100Hepatitis B_Homo sapiens_hsa051610.71337900
101Viral carcinogenesis_Homo sapiens_hsa052030.70828215
102Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.69213270
103Malaria_Homo sapiens_hsa051440.69162738
104Endometrial cancer_Homo sapiens_hsa052130.69060537
105Regulation of actin cytoskeleton_Homo sapiens_hsa048100.67877319
106Primary immunodeficiency_Homo sapiens_hsa053400.67599890
107Glioma_Homo sapiens_hsa052140.67510801
108Insulin secretion_Homo sapiens_hsa049110.66359970
109Antigen processing and presentation_Homo sapiens_hsa046120.66355933
110Estrogen signaling pathway_Homo sapiens_hsa049150.65808529
111Taste transduction_Homo sapiens_hsa047420.64724656
112Non-small cell lung cancer_Homo sapiens_hsa052230.64414382
113Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.64088812
114Small cell lung cancer_Homo sapiens_hsa052220.63863949
115Cardiac muscle contraction_Homo sapiens_hsa042600.63399468
116Circadian entrainment_Homo sapiens_hsa047130.62998026
117Aldosterone synthesis and secretion_Homo sapiens_hsa049250.59918030
118Amphetamine addiction_Homo sapiens_hsa050310.59881455
119Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.59545730
120Cholinergic synapse_Homo sapiens_hsa047250.59415400
121Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58694873
122Leukocyte transendothelial migration_Homo sapiens_hsa046700.57839960
123Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.56873026
124Platelet activation_Homo sapiens_hsa046110.56511377
125Oxidative phosphorylation_Homo sapiens_hsa001900.56188169
126Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55646087
127Shigellosis_Homo sapiens_hsa051310.55421858
128Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.55305024
129Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.55081356
130Prolactin signaling pathway_Homo sapiens_hsa049170.54281149
131Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.54231650
132GABAergic synapse_Homo sapiens_hsa047270.53141836
133PI3K-Akt signaling pathway_Homo sapiens_hsa041510.52119879
134Apoptosis_Homo sapiens_hsa042100.51604191
135Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.51275094
136Legionellosis_Homo sapiens_hsa051340.50897095
137Intestinal immune network for IgA production_Homo sapiens_hsa046720.50874289
138Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.50668316
139NF-kappa B signaling pathway_Homo sapiens_hsa040640.50021817
140Sulfur relay system_Homo sapiens_hsa041220.49969468
141Bladder cancer_Homo sapiens_hsa052190.49891097
142Dilated cardiomyopathy_Homo sapiens_hsa054140.49464151
143Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.48746902
144Central carbon metabolism in cancer_Homo sapiens_hsa052300.48718943
145Olfactory transduction_Homo sapiens_hsa047400.48480379
146Morphine addiction_Homo sapiens_hsa050320.47771488
147Viral myocarditis_Homo sapiens_hsa054160.47330930
148Cysteine and methionine metabolism_Homo sapiens_hsa002700.47150184
149Alzheimers disease_Homo sapiens_hsa050100.46813435
150AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46449888
151RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.46428349
152One carbon pool by folate_Homo sapiens_hsa006700.46027542
153Phototransduction_Homo sapiens_hsa047440.43205072
154Arachidonic acid metabolism_Homo sapiens_hsa005900.42925321
155Vibrio cholerae infection_Homo sapiens_hsa051100.42209613

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