ARMT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)5.43255683
2proteasome assembly (GO:0043248)4.95820195
3microtubule depolymerization (GO:0007019)4.46731393
4DNA strand renaturation (GO:0000733)4.46412453
5establishment of integrated proviral latency (GO:0075713)4.45958861
6centriole assembly (GO:0098534)4.44693629
7axonemal dynein complex assembly (GO:0070286)4.17642755
8motile cilium assembly (GO:0044458)4.08612307
9negative regulation of DNA-dependent DNA replication (GO:2000104)4.03908686
10mitotic metaphase plate congression (GO:0007080)4.02641520
11ribosome assembly (GO:0042255)4.00169043
12negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.96929659
13regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.85953809
14kinetochore organization (GO:0051383)3.81545144
15DNA integration (GO:0015074)3.81167984
16protein K6-linked ubiquitination (GO:0085020)3.77684300
17IMP biosynthetic process (GO:0006188)3.73954620
18kinetochore assembly (GO:0051382)3.73720230
19piRNA metabolic process (GO:0034587)3.72760032
20L-serine metabolic process (GO:0006563)3.70004227
21centriole replication (GO:0007099)3.67345414
22DNA replication checkpoint (GO:0000076)3.64322091
23negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.63428159
24negative regulation of ligase activity (GO:0051352)3.63428159
25protein localization to kinetochore (GO:0034501)3.62206098
26positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.61584249
27meiotic chromosome segregation (GO:0045132)3.59061883
28metaphase plate congression (GO:0051310)3.58394428
29anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.58055974
30DNA methylation involved in gamete generation (GO:0043046)3.56139956
31DNA ligation (GO:0006266)3.54634183
32purine nucleobase biosynthetic process (GO:0009113)3.48937846
33DNA synthesis involved in DNA repair (GO:0000731)3.46488132
34viral mRNA export from host cell nucleus (GO:0046784)3.44975218
35regulation of DNA endoreduplication (GO:0032875)3.40866758
36male meiosis (GO:0007140)3.40503863
37anterior/posterior axis specification, embryo (GO:0008595)3.38645295
38regulation of cellular amino acid metabolic process (GO:0006521)3.37906690
39regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.36449324
40IMP metabolic process (GO:0046040)3.36167994
41non-recombinational repair (GO:0000726)3.36096840
42double-strand break repair via nonhomologous end joining (GO:0006303)3.36096840
43polyketide metabolic process (GO:0030638)3.32294113
44doxorubicin metabolic process (GO:0044598)3.32294113
45daunorubicin metabolic process (GO:0044597)3.32294113
46establishment of viral latency (GO:0019043)3.31321708
47superoxide anion generation (GO:0042554)3.30974503
48synapsis (GO:0007129)3.29826702
49DNA strand elongation involved in DNA replication (GO:0006271)3.29452121
50regulation of nuclear cell cycle DNA replication (GO:0033262)3.28907479
51DNA replication-dependent nucleosome assembly (GO:0006335)3.25636211
52DNA replication-dependent nucleosome organization (GO:0034723)3.25636211
53signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.20292275
54signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.20292275
55signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.20292275
56DNA strand elongation (GO:0022616)3.19860337
57intestinal epithelial cell development (GO:0060576)3.19541445
58CENP-A containing nucleosome assembly (GO:0034080)3.19322382
59DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.16460198
60signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.15319882
61intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.15319882
62histone mRNA metabolic process (GO:0008334)3.13855545
63signal transduction involved in DNA integrity checkpoint (GO:0072401)3.11203346
64signal transduction involved in DNA damage checkpoint (GO:0072422)3.11203346
65establishment of protein localization to mitochondrial membrane (GO:0090151)3.10409169
66chromatin remodeling at centromere (GO:0031055)3.09457048
67formation of translation preinitiation complex (GO:0001731)3.08948373
68positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.08775884
69rRNA modification (GO:0000154)3.07896473
70signal transduction involved in cell cycle checkpoint (GO:0072395)3.05753722
71mitotic sister chromatid cohesion (GO:0007064)3.05624969
72nucleobase biosynthetic process (GO:0046112)3.03726256
73protein localization to chromosome, centromeric region (GO:0071459)3.02936089
74response to X-ray (GO:0010165)3.02316659
75spindle checkpoint (GO:0031577)3.01973911
76regulation of ubiquitin-protein transferase activity (GO:0051438)3.00480467
77single strand break repair (GO:0000012)2.99771821
78female gonad development (GO:0008585)2.99353007
79mitochondrial RNA metabolic process (GO:0000959)2.99013866
80positive regulation of ligase activity (GO:0051351)2.96591365
81protein complex localization (GO:0031503)2.96345186
82G1/S transition of mitotic cell cycle (GO:0000082)2.96237365
83cell cycle G1/S phase transition (GO:0044843)2.96237365
84cullin deneddylation (GO:0010388)2.95491191
85G-protein coupled receptor internalization (GO:0002031)2.95332108
86mitotic spindle checkpoint (GO:0071174)2.94907159
87epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.94356878
88negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.93407790
89negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.93407790
90negative regulation of mitotic sister chromatid segregation (GO:0033048)2.93407790
91negative regulation of mitotic sister chromatid separation (GO:2000816)2.93407790
92negative regulation of sister chromatid segregation (GO:0033046)2.93407790
93histone exchange (GO:0043486)2.92553278
94exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.91709154
95preassembly of GPI anchor in ER membrane (GO:0016254)2.91686758
96mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.91176845
97DNA damage response, detection of DNA damage (GO:0042769)2.91160310
98regulation of ligase activity (GO:0051340)2.90505569
99regulation of centriole replication (GO:0046599)2.89984478
100replicative senescence (GO:0090399)2.89780274
101chaperone-mediated protein transport (GO:0072321)2.89267426
102multicellular organism reproduction (GO:0032504)2.89247070
103negative regulation of chromosome segregation (GO:0051985)2.89169676
104vagina development (GO:0060068)2.89108690
105acrosome reaction (GO:0007340)2.87873159
106mismatch repair (GO:0006298)2.87813716
107mitotic G2/M transition checkpoint (GO:0044818)2.87206042
108reciprocal meiotic recombination (GO:0007131)2.85533911
109reciprocal DNA recombination (GO:0035825)2.85533911
110protein neddylation (GO:0045116)2.85268477
111regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.85150091
112energy homeostasis (GO:0097009)2.84731151
113regulation of chromosome segregation (GO:0051983)2.83231670
114DNA catabolic process, exonucleolytic (GO:0000738)2.82882310
115establishment of chromosome localization (GO:0051303)2.82203709
116regulation of DNA damage checkpoint (GO:2000001)2.81275697
117ATP-dependent chromatin remodeling (GO:0043044)2.81101919
118DNA double-strand break processing (GO:0000729)2.80115230
119negative regulation of granulocyte differentiation (GO:0030853)2.79970963
120rRNA methylation (GO:0031167)2.79627298
121folic acid-containing compound biosynthetic process (GO:0009396)2.79446125
122nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.78943096
123tRNA aminoacylation for protein translation (GO:0006418)2.78676478
124maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.78019873
125tricarboxylic acid cycle (GO:0006099)2.76776957
126nodal signaling pathway (GO:0038092)2.76072772
127histone H3-K36 demethylation (GO:0070544)2.75988597
128amino acid activation (GO:0043038)2.75633691
129tRNA aminoacylation (GO:0043039)2.75633691
130epithelial cilium movement (GO:0003351)2.75578760
131mitotic sister chromatid segregation (GO:0000070)2.75356309
132androgen biosynthetic process (GO:0006702)2.75166963
133histone H3-K9 methylation (GO:0051567)2.74023484
134regulation of coenzyme metabolic process (GO:0051196)2.73919686
135regulation of cofactor metabolic process (GO:0051193)2.73919686
136regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.73575032
137chromosome organization involved in meiosis (GO:0070192)2.65330306
138male meiosis I (GO:0007141)2.64878279
139positive regulation of protein homodimerization activity (GO:0090073)2.64682317
140cilium movement (GO:0003341)2.64127663
141regulation of timing of cell differentiation (GO:0048505)2.62463462
142left/right axis specification (GO:0070986)2.62432373
143recombinational repair (GO:0000725)2.61266117
144adenosine metabolic process (GO:0046085)2.60430137
145regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.59185796
146regulation of mitotic spindle checkpoint (GO:1903504)2.59185796
147regulation of helicase activity (GO:0051095)2.59047364
148GPI anchor biosynthetic process (GO:0006506)2.58237683
149V(D)J recombination (GO:0033151)2.57909901
150telomere maintenance via telomerase (GO:0007004)2.55599255
151histone H3-K4 trimethylation (GO:0080182)2.54466040
152microtubule polymerization or depolymerization (GO:0031109)2.53140301
153double-strand break repair via homologous recombination (GO:0000724)2.50344540
154cell proliferation in forebrain (GO:0021846)2.50166134
155sulfate transport (GO:0008272)2.49301162
156telomere maintenance via semi-conservative replication (GO:0032201)2.47465589
157sperm-egg recognition (GO:0035036)2.45913387
158GPI anchor metabolic process (GO:0006505)2.45830643
159auditory receptor cell stereocilium organization (GO:0060088)2.43805017
160sulfate transmembrane transport (GO:1902358)2.42896514
161regulation of development, heterochronic (GO:0040034)2.42719405
162histone H3-K9 modification (GO:0061647)2.41662636
163telomere maintenance via recombination (GO:0000722)2.41440143
164regulation of histone H3-K9 methylation (GO:0051570)2.41050764
165interkinetic nuclear migration (GO:0022027)2.40515681
166negative regulation of DNA recombination (GO:0045910)2.40377714
167lymphoid progenitor cell differentiation (GO:0002320)2.39958086
168telomere maintenance via telomere lengthening (GO:0010833)2.38300375
169DNA replication-independent nucleosome organization (GO:0034724)2.38106646
170DNA replication-independent nucleosome assembly (GO:0006336)2.38106646
171startle response (GO:0001964)2.36894249
172telomere maintenance (GO:0000723)2.36758508
173DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.36700086
174positive regulation of DNA-dependent DNA replication (GO:2000105)2.36508093
175deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.35894168
176tRNA methylation (GO:0030488)2.35160707
177DNA damage response, signal transduction resulting in transcription (GO:0042772)2.34970289
178intra-S DNA damage checkpoint (GO:0031573)2.34594115
179deoxyribonucleotide biosynthetic process (GO:0009263)2.34125914
180negative regulation of telomere maintenance (GO:0032205)2.34009766
181mesenchymal cell differentiation involved in kidney development (GO:0072161)2.33766901
182mesenchymal cell differentiation involved in renal system development (GO:2001012)2.33766901
183DNA recombination (GO:0006310)2.33145945
184telomere organization (GO:0032200)2.32913823
185dendritic cell chemotaxis (GO:0002407)2.32728787

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.82048686
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.62983213
3PCGF2_27294783_Chip-Seq_ESCs_Mouse3.40826111
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.33409881
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.31302468
6FLI1_27457419_Chip-Seq_LIVER_Mouse3.05081926
7PCGF2_27294783_Chip-Seq_NPCs_Mouse3.04724733
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.98166092
9CREB1_15753290_ChIP-ChIP_HEK293T_Human2.88155304
10NFE2_27457419_Chip-Seq_LIVER_Mouse2.86589935
11GBX2_23144817_ChIP-Seq_PC3_Human2.86253870
12SUZ12_27294783_Chip-Seq_NPCs_Mouse2.86001880
13AR_21909140_ChIP-Seq_LNCAP_Human2.82195826
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.78328459
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.77232694
16ELK1_19687146_ChIP-ChIP_HELA_Human2.66135219
17ZFP57_27257070_Chip-Seq_ESCs_Mouse2.64103129
18MYC_19030024_ChIP-ChIP_MESCs_Mouse2.52569636
19JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.45127629
20PADI4_21655091_ChIP-ChIP_MCF-7_Human2.41640345
21MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.41497349
22EZH2_27294783_Chip-Seq_NPCs_Mouse2.37021534
23E2F4_17652178_ChIP-ChIP_JURKAT_Human2.33816180
24MYC_19079543_ChIP-ChIP_MESCs_Mouse2.33125632
25NELFA_20434984_ChIP-Seq_ESCs_Mouse2.32915737
26BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.32454883
27KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.30779366
28EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.27952572
29HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.23429674
30ETS1_20019798_ChIP-Seq_JURKAT_Human2.21191092
31TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.18582172
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.17721028
33MYC_18358816_ChIP-ChIP_MESCs_Mouse2.12081085
34CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.11934463
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.10041626
36TP63_19390658_ChIP-ChIP_HaCaT_Human2.08601031
37EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse2.08061234
38SUZ12_18555785_Chip-Seq_ESCs_Mouse2.05833361
39GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.04671831
40STAT3_18555785_Chip-Seq_ESCs_Mouse2.04390443
41DCP1A_22483619_ChIP-Seq_HELA_Human2.02320505
42P53_22387025_ChIP-Seq_ESCs_Mouse2.02069408
43E2F1_18555785_Chip-Seq_ESCs_Mouse2.01195124
44E2F1_18555785_ChIP-Seq_MESCs_Mouse2.00784951
45NANOG_18555785_Chip-Seq_ESCs_Mouse2.00260784
46TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.99410907
47GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.98943999
48NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.98867717
49EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.98767031
50MYCN_18555785_ChIP-Seq_MESCs_Mouse1.98666635
51FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.97066333
52VDR_23849224_ChIP-Seq_CD4+_Human1.95302197
53RUNX1_27457419_Chip-Seq_LIVER_Mouse1.90988784
54P300_18555785_Chip-Seq_ESCs_Mouse1.90909692
55FOXP3_21729870_ChIP-Seq_TREG_Human1.90635787
56NMYC_18555785_Chip-Seq_ESCs_Mouse1.90096504
57OCT4_18555785_Chip-Seq_ESCs_Mouse1.89104808
58EZH2_22144423_ChIP-Seq_EOC_Human1.85639920
59BMI1_23680149_ChIP-Seq_NPCS_Mouse1.84932506
60IGF1R_20145208_ChIP-Seq_DFB_Human1.83024656
61CMYC_18555785_Chip-Seq_ESCs_Mouse1.80045147
62FOXM1_23109430_ChIP-Seq_U2OS_Human1.79133337
63ELF1_17652178_ChIP-ChIP_JURKAT_Human1.79021551
64E2F1_21310950_ChIP-Seq_MCF-7_Human1.78219376
65ZFX_18555785_Chip-Seq_ESCs_Mouse1.77627388
66ESRRB_18555785_Chip-Seq_ESCs_Mouse1.74076391
67NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.73462190
68KLF4_18555785_Chip-Seq_ESCs_Mouse1.72547561
69PU1_27457419_Chip-Seq_LIVER_Mouse1.72170742
70PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.71910321
71ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.70435071
72NOTCH1_21737748_ChIP-Seq_TLL_Human1.68568753
73SOX2_18555785_Chip-Seq_ESCs_Mouse1.68398093
74CBX2_27304074_Chip-Seq_ESCs_Mouse1.68250353
75HOXB4_20404135_ChIP-ChIP_EML_Mouse1.68216063
76POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68166045
77CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.66787986
78YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.65442484
79POU3F2_20337985_ChIP-ChIP_501MEL_Human1.65263765
80ZFX_18555785_ChIP-Seq_MESCs_Mouse1.64926506
81RBPJ_22232070_ChIP-Seq_NCS_Mouse1.63161803
82NANOG_16153702_ChIP-ChIP_HESCs_Human1.62745866
83CRX_20693478_ChIP-Seq_RETINA_Mouse1.62368332
84OCT4_21477851_ChIP-Seq_ESCs_Mouse1.62306984
85THAP11_20581084_ChIP-Seq_MESCs_Mouse1.61692444
86CTCF_18555785_Chip-Seq_ESCs_Mouse1.61378281
87FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.60713498
88SMAD1_18555785_Chip-Seq_ESCs_Mouse1.60648012
89SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.60593360
90GABP_19822575_ChIP-Seq_HepG2_Human1.54807525
91KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.54489105
92KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.54489105
93KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.54489105
94SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.53764516
95TAF15_26573619_Chip-Seq_HEK293_Human1.53554050
96IRF1_19129219_ChIP-ChIP_H3396_Human1.51120783
97EWS_26573619_Chip-Seq_HEK293_Human1.50845907
98HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.50626326
99TTF2_22483619_ChIP-Seq_HELA_Human1.49091330
100ESR1_15608294_ChIP-ChIP_MCF-7_Human1.46272322
101TAL1_26923725_Chip-Seq_HPCs_Mouse1.43165255
102RNF2_27304074_Chip-Seq_NSC_Mouse1.39502279
103SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.39441355
104XRN2_22483619_ChIP-Seq_HELA_Human1.36254214
105NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.35931399
106FUS_26573619_Chip-Seq_HEK293_Human1.35562878
107POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.34161521
108POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.32162599
109SRF_21415370_ChIP-Seq_HL-1_Mouse1.30601999
110P300_19829295_ChIP-Seq_ESCs_Human1.28402048
111ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.27984830
112IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.26761698
113ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.26309289
114KAP1_22055183_ChIP-Seq_ESCs_Mouse1.26069016
115LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25519075
116FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.24867624
117NANOG_18555785_ChIP-Seq_MESCs_Mouse1.24212093
118SOX17_20123909_ChIP-Seq_XEN_Mouse1.22481852
119POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.20733615
120TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20733615
121IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.20705019
122TCF3_18692474_ChIP-Seq_MEFs_Mouse1.20279917
123CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19897381
124SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.18689275
125ER_23166858_ChIP-Seq_MCF-7_Human1.16827239
126SOX2_16153702_ChIP-ChIP_HESCs_Human1.15961492
127PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.14329177
128POU5F1_16153702_ChIP-ChIP_HESCs_Human1.14309076
129MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.13689649
130NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.13646771
131CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.12676338
132KDM2B_26808549_Chip-Seq_REH_Human1.09700555
133SOX2_18555785_ChIP-Seq_MESCs_Mouse1.08316137
134SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.06812032
135VDR_22108803_ChIP-Seq_LS180_Human1.06005396
136CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.05817388
137CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.03376535
138LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.02455883
139MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.02299323
140ELF5_23300383_ChIP-Seq_T47D_Human1.01823356
141CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.01759105
142STAT1_17558387_ChIP-Seq_HELA_Human1.00941396
143MYC_18940864_ChIP-ChIP_HL60_Human0.98326736
144SALL1_21062744_ChIP-ChIP_HESCs_Human0.97342270
145EGR1_23403033_ChIP-Seq_LIVER_Mouse0.97280213
146E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.97212763
147TFEB_21752829_ChIP-Seq_HELA_Human0.95814154
148ESR1_20079471_ChIP-ChIP_T-47D_Human0.94818948
149SCL_19346495_ChIP-Seq_HPC-7_Human0.94775983
150TCF4_23295773_ChIP-Seq_U87_Human0.94242286
151RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.93057074
152ERG_20887958_ChIP-Seq_HPC-7_Mouse0.92776099
153KLF4_18555785_ChIP-Seq_MESCs_Mouse0.92660716
154CTBP1_25329375_ChIP-Seq_LNCAP_Human0.92280595
155NFYB_21822215_ChIP-Seq_K562_Human0.90428276
156KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.90349566
157KDM5A_27292631_Chip-Seq_BREAST_Human0.90295052
158CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.88939835
159EOMES_21245162_ChIP-Seq_HESCs_Human0.88612313
160SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.88192518
161KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.87048416
162SMAD4_21799915_ChIP-Seq_A2780_Human0.86238808
163IRF8_21731497_ChIP-ChIP_J774_Mouse0.85491692
164EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.84826322
165HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.84724359
166TCF3_18692474_ChIP-Seq_MESCs_Mouse0.84633829
167IRF8_22096565_ChIP-ChIP_GC-B_Human0.84278451
168EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.82851064
169ZNF274_21170338_ChIP-Seq_K562_Hela0.81952357
170EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.81943571
171STAT3_23295773_ChIP-Seq_U87_Human0.81439179
172TBL1_22424771_ChIP-Seq_293T_Human0.81136600
173FOXM1_26456572_ChIP-Seq_MCF-7_Human0.80599252
174GF1_26923725_Chip-Seq_HPCs_Mouse0.80433103
175UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.80140541
176PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.79642936
177STAT3_1855785_ChIP-Seq_MESCs_Mouse0.77774462
178ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.76696173
179RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.73349646
180SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.72402378

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis4.41117377
2MP0004957_abnormal_blastocyst_morpholog4.17700545
3MP0003890_abnormal_embryonic-extraembry4.04664609
4MP0008058_abnormal_DNA_repair3.75088953
5MP0001188_hyperpigmentation3.72686093
6MP0006292_abnormal_olfactory_placode3.48259530
7MP0008057_abnormal_DNA_replication3.45249228
8MP0003136_yellow_coat_color3.15601392
9MP0001986_abnormal_taste_sensitivity3.15511797
10MP0010094_abnormal_chromosome_stability3.05871490
11MP0002254_reproductive_system_inflammat3.03286341
12MP0003111_abnormal_nucleus_morphology2.67815341
13MP0002396_abnormal_hematopoietic_system2.53679990
14MP0004381_abnormal_hair_follicle2.50797852
15MP0008877_abnormal_DNA_methylation2.49798171
16MP0005409_darkened_coat_color2.44072849
17MP0005410_abnormal_fertilization2.43242987
18MP0004264_abnormal_extraembryonic_tissu2.32974780
19MP0005174_abnormal_tail_pigmentation2.31684951
20MP0002102_abnormal_ear_morphology2.29712530
21MP0003941_abnormal_skin_development2.24276671
22MP0006054_spinal_hemorrhage2.24037563
23MP0000015_abnormal_ear_pigmentation2.08758155
24MP0009672_abnormal_birth_weight1.98724035
25MP0000569_abnormal_digit_pigmentation1.94641174
26MP0005075_abnormal_melanosome_morpholog1.94254693
27MP0008995_early_reproductive_senescence1.90435693
28MP0003806_abnormal_nucleotide_metabolis1.85130281
29MP0001730_embryonic_growth_arrest1.82760995
30MP0002736_abnormal_nociception_after1.79296524
31MP0002277_abnormal_respiratory_mucosa1.79208426
32MP0005380_embryogenesis_phenotype1.77622839
33MP0001672_abnormal_embryogenesis/_devel1.77622839
34MP0003693_abnormal_embryo_hatching1.77261599
35MP0003786_premature_aging1.74351731
36MP0003718_maternal_effect1.73822180
37MP0003787_abnormal_imprinting1.68407444
38MP0001697_abnormal_embryo_size1.65649921
39MP0005423_abnormal_somatic_nervous1.62900034
40MP0002796_impaired_skin_barrier1.61087564
41MP0003186_abnormal_redox_activity1.58883123
42MP0002084_abnormal_developmental_patter1.58660825
43MP0003077_abnormal_cell_cycle1.54415453
44MP0002088_abnormal_embryonic_growth/wei1.52644342
45MP0003698_abnormal_male_reproductive1.50474091
46MP0003984_embryonic_growth_retardation1.50255548
47MP0010030_abnormal_orbit_morphology1.50095899
48MP0002085_abnormal_embryonic_tissue1.49459412
49MP0002210_abnormal_sex_determination1.48903443
50MP0008007_abnormal_cellular_replicative1.47521777
51MP0003567_abnormal_fetal_cardiomyocyte1.47037756
52MP0000490_abnormal_crypts_of1.46506536
53MP0010234_abnormal_vibrissa_follicle1.45340837
54MP0001929_abnormal_gametogenesis1.45184670
55MP0000383_abnormal_hair_follicle1.44764220
56MP0009697_abnormal_copulation1.44036665
57MP0002132_abnormal_respiratory_system1.43850391
58MP0010307_abnormal_tumor_latency1.42972495
59MP0000350_abnormal_cell_proliferation1.42137825
60MP0002095_abnormal_skin_pigmentation1.41538583
61MP0003119_abnormal_digestive_system1.39270184
62MP0005645_abnormal_hypothalamus_physiol1.39175960
63MP0005408_hypopigmentation1.36434140
64MP0005646_abnormal_pituitary_gland1.34163596
65MP0010352_gastrointestinal_tract_polyps1.33559760
66MP0005171_absent_coat_pigmentation1.30880216
67MP0002080_prenatal_lethality1.28199065
68MP0001727_abnormal_embryo_implantation1.27740277
69MP0001835_abnormal_antigen_presentation1.24859257
70MP0002751_abnormal_autonomic_nervous1.20866714
71MP0009703_decreased_birth_body1.18672727
72MP0002086_abnormal_extraembryonic_tissu1.14740130
73MP0005499_abnormal_olfactory_system1.14475178
74MP0005394_taste/olfaction_phenotype1.14475178
75MP0005379_endocrine/exocrine_gland_phen1.13791055
76MP0002938_white_spotting1.13699836
77MP0001286_abnormal_eye_development1.13070374
78MP0002160_abnormal_reproductive_system1.12956024
79MP0001800_abnormal_humoral_immune1.12509202
80MP0004808_abnormal_hematopoietic_stem1.10172345
81MP0005451_abnormal_body_composition1.10170862
82MP0001145_abnormal_male_reproductive1.09218145
83MP0005647_abnormal_sex_gland1.08752607
84MP0002697_abnormal_eye_size1.08501115
85MP0004742_abnormal_vestibular_system1.08493957
86MP0000647_abnormal_sebaceous_gland1.08488383
87MP0002233_abnormal_nose_morphology1.08450883
88MP0010678_abnormal_skin_adnexa1.08265482
89MP0008260_abnormal_autophagy1.08181928
90MP0001881_abnormal_mammary_gland1.06238971
91MP0003123_paternal_imprinting1.02541452
92MP0000358_abnormal_cell_content/1.02493071
93MP0006035_abnormal_mitochondrial_morpho1.02489014
94MP0005360_urolithiasis1.02187290
95MP0005377_hearing/vestibular/ear_phenot1.01733030
96MP0003878_abnormal_ear_physiology1.01733030
97MP0005671_abnormal_response_to1.01480328
98MP0000026_abnormal_inner_ear1.00061929
99MP0000653_abnormal_sex_gland0.99969232
100MP0005501_abnormal_skin_physiology0.99006067
101MP0002090_abnormal_vision0.98597890
102MP0001177_atelectasis0.98216186
103MP0005248_abnormal_Harderian_gland0.97935806
104MP0002111_abnormal_tail_morphology0.97540463
105MP0003195_calcinosis0.96854011
106MP0003763_abnormal_thymus_physiology0.96365693
107MP0000627_abnormal_mammary_gland0.96167878
108MP0003938_abnormal_ear_development0.96167107
109MP0000537_abnormal_urethra_morphology0.96117882
110MP0002163_abnormal_gland_morphology0.95433854
111MP0001790_abnormal_immune_system0.93302203
112MP0005387_immune_system_phenotype0.93302203
113MP0000049_abnormal_middle_ear0.93108403
114MP0004197_abnormal_fetal_growth/weight/0.92713656
115MP0003936_abnormal_reproductive_system0.92165716
116MP0008789_abnormal_olfactory_epithelium0.89907540
117MP0001119_abnormal_female_reproductive0.89413756
118MP0003221_abnormal_cardiomyocyte_apopto0.89314571
119MP0002148_abnormal_hypersensitivity_rea0.89106590
120MP0005367_renal/urinary_system_phenotyp0.88613582
121MP0000516_abnormal_urinary_system0.88613582
122MP0002452_abnormal_antigen_presenting0.88590555
123MP0001486_abnormal_startle_reflex0.86887361
124MP0000470_abnormal_stomach_morphology0.86839892
125MP0004133_heterotaxia0.86669406
126MP0002723_abnormal_immune_serum0.86515668
127MP0000313_abnormal_cell_death0.85826841
128MP0002398_abnormal_bone_marrow0.85414892
129MP0001186_pigmentation_phenotype0.85343840
130MP0004142_abnormal_muscle_tone0.84192026
131MP0009785_altered_susceptibility_to0.83797233
132MP0005389_reproductive_system_phenotype0.83673685
133MP0000427_abnormal_hair_cycle0.82286847
134MP0001919_abnormal_reproductive_system0.80858703
135MP0002420_abnormal_adaptive_immunity0.80635518
136MP0000703_abnormal_thymus_morphology0.80575434
137MP0008932_abnormal_embryonic_tissue0.79891469
138MP0001819_abnormal_immune_cell0.79806911
139MP0004782_abnormal_surfactant_physiolog0.78997865
140MP0001963_abnormal_hearing_physiology0.78688910
141MP0002638_abnormal_pupillary_reflex0.78027157
142MP0002419_abnormal_innate_immunity0.77585771
143MP0002075_abnormal_coat/hair_pigmentati0.77287136
144MP0006036_abnormal_mitochondrial_physio0.75437515
145MP0002098_abnormal_vibrissa_morphology0.75429271
146MP0000716_abnormal_immune_system0.75196872
147MP0003937_abnormal_limbs/digits/tail_de0.74980399
148MP0005551_abnormal_eye_electrophysiolog0.74695531
149MP0001293_anophthalmia0.74659951
150MP0000689_abnormal_spleen_morphology0.74457134
151MP0001346_abnormal_lacrimal_gland0.73313527
152MP0001764_abnormal_homeostasis0.73184057
153MP0005025_abnormal_response_to0.73086352
154MP0002249_abnormal_larynx_morphology0.72261698
155MP0003315_abnormal_perineum_morphology0.71355958
156MP0001849_ear_inflammation0.71112142
157MP0004134_abnormal_chest_morphology0.70150655
158MP0001873_stomach_inflammation0.69932618
159MP0000372_irregular_coat_pigmentation0.69875645
160MP0000428_abnormal_craniofacial_morphol0.69668323
161MP0009384_cardiac_valve_regurgitation0.69242968
162MP0009780_abnormal_chondrocyte_physiolo0.68833000
163MP0000579_abnormal_nail_morphology0.68592422
164MP0000462_abnormal_digestive_system0.68395541
165MP0002161_abnormal_fertility/fecundity0.68036126
166MP0002722_abnormal_immune_system0.66918274
167MP0003724_increased_susceptibility_to0.66822934
168MP0002735_abnormal_chemical_nociception0.66292156
169MP0005253_abnormal_eye_physiology0.65711779

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)7.15643609
2Chromsome breakage (HP:0040012)6.51006821
3Absent/shortened dynein arms (HP:0200106)5.05919844
4Dynein arm defect of respiratory motile cilia (HP:0012255)5.05919844
5Duplicated collecting system (HP:0000081)4.73572428
6Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.63375720
7Abnormality of the renal collecting system (HP:0004742)4.40415940
8Abnormal respiratory motile cilium morphology (HP:0005938)3.87151905
9Abnormal respiratory epithelium morphology (HP:0012253)3.87151905
10Abnormality of the preputium (HP:0100587)3.71388204
11Abnormal ciliary motility (HP:0012262)3.65247425
12Aplasia/Hypoplasia of the uvula (HP:0010293)3.63128566
13Prostate neoplasm (HP:0100787)3.52148114
14Abnormal respiratory motile cilium physiology (HP:0012261)3.44162103
15Meckel diverticulum (HP:0002245)3.41984785
16Abnormality of chromosome stability (HP:0003220)3.37637950
17Abnormal umbilical cord blood vessels (HP:0011403)3.36358821
18Single umbilical artery (HP:0001195)3.36358821
19Abnormality of the fetal cardiovascular system (HP:0010948)3.36358821
20Abnormality of the ileum (HP:0001549)3.28277033
21Multiple enchondromatosis (HP:0005701)3.26270019
22Clubbing of toes (HP:0100760)3.22860536
23Abnormality of DNA repair (HP:0003254)3.20449331
24Ectopic kidney (HP:0000086)3.16260513
25Abnormality of methionine metabolism (HP:0010901)3.05618938
26Breast carcinoma (HP:0003002)2.91609570
27Upper limb muscle weakness (HP:0003484)2.87448675
28Tubulointerstitial nephritis (HP:0001970)2.85627418
29Abnormality of the umbilical cord (HP:0010881)2.84178649
30Duplication of thumb phalanx (HP:0009942)2.82552306
31Microvesicular hepatic steatosis (HP:0001414)2.82064595
32Abnormality of serum amino acid levels (HP:0003112)2.81525402
33Abnormality of alanine metabolism (HP:0010916)2.80194654
34Hyperalaninemia (HP:0003348)2.80194654
35Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.80194654
36Renal cortical cysts (HP:0000803)2.76607180
37Increased serum pyruvate (HP:0003542)2.74666927
38Colon cancer (HP:0003003)2.72989534
39Neoplasm of the adrenal gland (HP:0100631)2.71690851
40Abnormality of the labia minora (HP:0012880)2.70692667
41Reduced antithrombin III activity (HP:0001976)2.68663184
42Reticulocytopenia (HP:0001896)2.66756672
43Nephronophthisis (HP:0000090)2.63324735
44Ependymoma (HP:0002888)2.62426578
45Abnormality of the carotid arteries (HP:0005344)2.59651742
46Increased hepatocellular lipid droplets (HP:0006565)2.56918756
47Abnormality of glycolysis (HP:0004366)2.56895931
48Abnormality of the prostate (HP:0008775)2.52940157
49Abnormality of aspartate family amino acid metabolism (HP:0010899)2.50262357
50Methylmalonic acidemia (HP:0002912)2.46754893
51Septo-optic dysplasia (HP:0100842)2.43445454
52Nephroblastoma (Wilms tumor) (HP:0002667)2.43322482
53Birth length less than 3rd percentile (HP:0003561)2.42975722
54Recurrent sinusitis (HP:0011108)2.40073896
55Febrile seizures (HP:0002373)2.38783047
56Small intestinal stenosis (HP:0012848)2.35530468
57Duodenal stenosis (HP:0100867)2.35530468
58Bone marrow hypocellularity (HP:0005528)2.33162592
59Abnormality of the renal medulla (HP:0100957)2.32868163
60Congenital stationary night blindness (HP:0007642)2.31647032
61Hyperglycinemia (HP:0002154)2.31330461
62Rhabdomyosarcoma (HP:0002859)2.29618633
63Intestinal atresia (HP:0011100)2.28554709
64Abnormalities of placenta or umbilical cord (HP:0001194)2.27183818
65Bifid tongue (HP:0010297)2.25339246
66Type I transferrin isoform profile (HP:0003642)2.25155123
67Embryonal renal neoplasm (HP:0011794)2.24279288
68Medulloblastoma (HP:0002885)2.23599875
69Lipid accumulation in hepatocytes (HP:0006561)2.21100985
70Spastic diplegia (HP:0001264)2.20476345
71Acute encephalopathy (HP:0006846)2.20328789
72Ovarian neoplasm (HP:0100615)2.19287642
73Aplasia/Hypoplasia of the sacrum (HP:0008517)2.18646810
74Increased CSF lactate (HP:0002490)2.17862740
75Supernumerary spleens (HP:0009799)2.17132619
76Postaxial foot polydactyly (HP:0001830)2.16766171
77Stenosis of the external auditory canal (HP:0000402)2.16698159
78Median cleft lip (HP:0000161)2.15321095
79Abnormality of the renal cortex (HP:0011035)2.15184580
80Microglossia (HP:0000171)2.14960506
81Rhinitis (HP:0012384)2.14361092
82Agnosia (HP:0010524)2.13843717
83Horseshoe kidney (HP:0000085)2.13264644
84Double outlet right ventricle (HP:0001719)2.13175985
85Congenital malformation of the right heart (HP:0011723)2.13175985
86Myelodysplasia (HP:0002863)2.12483118
87Decreased central vision (HP:0007663)2.12041754
88Short thumb (HP:0009778)2.11809164
89Abnormality of serine family amino acid metabolism (HP:0010894)2.09900044
90Abnormality of glycine metabolism (HP:0010895)2.09900044
91Triphalangeal thumb (HP:0001199)2.09813989
92Abnormality of pyrimidine metabolism (HP:0004353)2.09723735
93Acute necrotizing encephalopathy (HP:0006965)2.08711391
94Abnormality of incisor morphology (HP:0011063)2.07526673
95Absent thumb (HP:0009777)2.06692424
96Abnormality of the parathyroid morphology (HP:0011766)2.04765989
97Hyperglycinuria (HP:0003108)2.04688171
98Impulsivity (HP:0100710)2.04071858
99Megaloblastic anemia (HP:0001889)2.04009467
100Optic nerve hypoplasia (HP:0000609)2.03370924
101Recurrent pneumonia (HP:0006532)2.01470256
102Congenital hepatic fibrosis (HP:0002612)2.00891773
103Preaxial hand polydactyly (HP:0001177)2.00696787
104Carpal bone hypoplasia (HP:0001498)1.99991909
105True hermaphroditism (HP:0010459)1.99663054
106Uterine neoplasm (HP:0010784)1.98807979
107Glioma (HP:0009733)1.98552896
108Gonadotropin excess (HP:0000837)1.97421971
109Acute lymphatic leukemia (HP:0006721)1.97382199
110Absent eyebrow (HP:0002223)1.96469341
111Absent septum pellucidum (HP:0001331)1.96386548
112Hypoglycemic coma (HP:0001325)1.96039454
113Osteomalacia (HP:0002749)1.94994300
114Abnormality of the duodenum (HP:0002246)1.93976098
115Anal stenosis (HP:0002025)1.93602146
116Methylmalonic aciduria (HP:0012120)1.93577766
117Aplasia cutis congenita (HP:0001057)1.93317955
118Myelomeningocele (HP:0002475)1.92053448
119Degeneration of anterior horn cells (HP:0002398)1.91708117
120Abnormality of the anterior horn cell (HP:0006802)1.91708117
121Cerebral edema (HP:0002181)1.91299345
122Pancreatic islet-cell hyperplasia (HP:0004510)1.91256919
123Oligohydramnios (HP:0001562)1.90592003
124Increased serum lactate (HP:0002151)1.89926898
125Sloping forehead (HP:0000340)1.89414956
126Respiratory difficulties (HP:0002880)1.87709259
127Hypoplastic pelvis (HP:0008839)1.86901278
128Bronchiectasis (HP:0002110)1.85602181
129Septate vagina (HP:0001153)1.85519902
130Abnormal lung lobation (HP:0002101)1.84441036
131Bilateral microphthalmos (HP:0007633)1.83833199
132Facial cleft (HP:0002006)1.83560387
133Leukopenia (HP:0001882)1.83353531
134Asplenia (HP:0001746)1.82973928
135Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.81741675
136Abnormal protein N-linked glycosylation (HP:0012347)1.81741675
137Abnormal protein glycosylation (HP:0012346)1.81741675
138Abnormal glycosylation (HP:0012345)1.81741675
139Fair hair (HP:0002286)1.80925849
140Abnormality of the septum pellucidum (HP:0007375)1.80913645
141Male pseudohermaphroditism (HP:0000037)1.80107760
142Neoplasm of the colon (HP:0100273)1.78237795
143Papillary thyroid carcinoma (HP:0002895)1.76374985
144Fused cervical vertebrae (HP:0002949)1.76257507
145White forelock (HP:0002211)1.75779791
146Abnormality of homocysteine metabolism (HP:0010919)1.75189775
147Homocystinuria (HP:0002156)1.75189775
148Abnormality of sulfur amino acid metabolism (HP:0004339)1.75072789
149Intrahepatic cholestasis (HP:0001406)1.74972007
150Mesomelia (HP:0003027)1.74572934
151Abnormality of the incisor (HP:0000676)1.73840939
152Volvulus (HP:0002580)1.73519805
153Hypergonadotropic hypogonadism (HP:0000815)1.71608556
154Absent radius (HP:0003974)1.71134946
155Attenuation of retinal blood vessels (HP:0007843)1.69775085
156Astigmatism (HP:0000483)1.69222894
157Aplasia/Hypoplasia of the earlobes (HP:0009906)1.67990509
158Aplasia/Hypoplasia of the tibia (HP:0005772)1.66966681
159Absent rod-and cone-mediated responses on ERG (HP:0007688)1.66331822
160Aplasia involving forearm bones (HP:0009822)1.65817665
161Absent forearm bone (HP:0003953)1.65817665
162Chronic hepatic failure (HP:0100626)1.65575325
163Abnormal spermatogenesis (HP:0008669)1.65474982
164Patchy hypopigmentation of hair (HP:0011365)1.65012392
165Dry hair (HP:0011359)1.64849050
166Bile duct proliferation (HP:0001408)1.64261556
167Abnormal biliary tract physiology (HP:0012439)1.64261556
168Parakeratosis (HP:0001036)1.63813354
169Pancreatic fibrosis (HP:0100732)1.63171332
170Renal agenesis (HP:0000104)1.63127975
171Conical tooth (HP:0000698)1.63038110
172Aplasia/Hypoplasia of the spleen (HP:0010451)1.60878037
173Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.59525114
174Abnormal hair whorl (HP:0010721)1.59287056
175Pancytopenia (HP:0001876)1.58378995
176Agammaglobulinemia (HP:0004432)1.58341536
177Congenital sensorineural hearing impairment (HP:0008527)1.54891907

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PBK4.24532812
2CASK3.78152248
3STK163.73379146
4TRIM283.38073011
5MST42.89282220
6TSSK62.87372020
7ZAK2.71458014
8EIF2AK22.64157159
9NEK12.49237807
10SRPK12.46585830
11TXK2.42337957
12IRAK42.38838189
13ACVR1B2.38271106
14VRK22.27954535
15IRAK32.16541327
16YES12.11184082
17MAP3K122.07192971
18TNIK2.05961677
19INSRR2.03870107
20GRK11.99290642
21MKNK21.92316121
22SCYL21.90286005
23TAF11.85446454
24MAP3K141.85221378
25BRD41.84678136
26SIK31.82202689
27CLK11.72749458
28PKN21.72594031
29TTK1.63829942
30ATR1.59247409
31ADRBK21.55477945
32BRSK21.52958359
33MKNK11.51473599
34TEC1.50628354
35CDK121.47693108
36PAK41.46406662
37BMPR1B1.40423276
38CDC71.37858209
39BLK1.34670818
40PLK41.33711347
41MUSK1.32356668
42ERBB31.29534151
43BCR1.28453286
44IKBKE1.25497306
45PRPF4B1.24878077
46CHEK21.22227867
47NEK61.22104494
48TLK11.19969299
49CDK71.19921681
50CDK81.18383512
51RPS6KB21.16873013
52TGFBR11.15508038
53VRK11.15272655
54NME21.14890295
55WNK31.14054147
56ERBB41.12290383
57SIK21.09805408
58FGFR11.01567750
59IKBKB1.01306418
60PIK3CG0.98770966
61NEK20.97232510
62CDK30.93814328
63RIPK40.93679554
64PLK10.93459804
65PNCK0.91691454
66PIK3CA0.91334216
67PKN10.90880512
68STK390.90369167
69BTK0.90074855
70DYRK30.89079135
71TNK20.88775887
72OXSR10.88488455
73IRAK10.88450350
74TAOK30.87454919
75NUAK10.84623525
76IRAK20.83013176
77STK38L0.82881144
78STK40.82408469
79SGK20.80633251
80EIF2AK10.80514022
81NME10.80227032
82ATM0.79255902
83KIT0.78373422
84PLK20.76187970
85BUB10.75446416
86CHEK10.72650260
87LYN0.71022545
88MAPK130.69619857
89MAP2K70.69197152
90BRSK10.68488173
91CDK60.68369657
92RPS6KA50.67330043
93ALK0.66490825
94STK100.65800987
95AKT30.65653751
96BMPR20.64599388
97WEE10.63393932
98PASK0.62264840
99STK30.62205729
100GRK70.61978543
101PIM10.60994094
102RPS6KA40.59964961
103CSNK1G10.57501596
104MAPK70.57217175
105AURKB0.55931122
106PDK20.55871653
107MAP4K10.53753452
108EIF2AK30.53462001
109FGFR20.52692213
110CCNB10.51988713
111EPHA20.50895637
112SYK0.49647311
113HCK0.49344918
114CDK90.49250872
115LATS10.48933848
116MELK0.48158423
117NLK0.46501033
118BCKDK0.43873003
119CSNK2A20.43204159
120ILK0.42907194
121LCK0.42077956
122PRKCQ0.40997206
123FLT30.40969560
124JAK30.40962161
125CDK40.40675579
126DAPK10.39843247
127PRKAA20.39089807
128MAP3K80.38461663
129CSF1R0.38303225
130AKT20.38186030
131PRKCI0.38169930
132CDK10.37328503
133JAK10.37132516
134PDK30.36529249
135PDK40.36529249
136AKT10.36106722
137CSNK2A10.35801492
138CSNK1E0.35615066
139RPS6KB10.34736679
140PLK30.34256399
141AURKA0.34150081
142CHUK0.34120251
143SGK10.33951371
144TBK10.33590390
145STK240.33440308
146CSNK1G30.33095387
147FES0.32937372
148PRKG10.32028927
149MYLK0.31765787
150FER0.31640834
151TAOK20.31416710
152LIMK10.29639218
153CSNK1G20.27876036
154CDK180.25804034
155TESK10.25256111
156CSNK1A1L0.20739219
157CDK20.20021490
158DYRK20.19280998

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.63087787
2Fanconi anemia pathway_Homo sapiens_hsa034604.53353261
3Homologous recombination_Homo sapiens_hsa034403.83862058
4Non-homologous end-joining_Homo sapiens_hsa034503.25628472
5Mismatch repair_Homo sapiens_hsa034302.82318740
6DNA replication_Homo sapiens_hsa030302.79846715
7Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.69759230
8Protein export_Homo sapiens_hsa030602.55063698
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.53814476
102-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.24817860
11Base excision repair_Homo sapiens_hsa034102.24642942
12Propanoate metabolism_Homo sapiens_hsa006402.21996799
13One carbon pool by folate_Homo sapiens_hsa006702.20894681
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.08766476
15Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.07855903
16Nucleotide excision repair_Homo sapiens_hsa034202.07797280
17Basal transcription factors_Homo sapiens_hsa030222.03359134
18NF-kappa B signaling pathway_Homo sapiens_hsa040641.87348209
19Primary immunodeficiency_Homo sapiens_hsa053401.85254263
20Pyruvate metabolism_Homo sapiens_hsa006201.78095753
21Oxidative phosphorylation_Homo sapiens_hsa001901.78076527
22Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.77530619
23Cysteine and methionine metabolism_Homo sapiens_hsa002701.77061938
24Phototransduction_Homo sapiens_hsa047441.76631490
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.74031010
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.60634568
27Parkinsons disease_Homo sapiens_hsa050121.56614836
28Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.56028669
29Pyrimidine metabolism_Homo sapiens_hsa002401.51936218
30Intestinal immune network for IgA production_Homo sapiens_hsa046721.50509109
31Hematopoietic cell lineage_Homo sapiens_hsa046401.45610653
32Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.45553625
33Spliceosome_Homo sapiens_hsa030401.45517019
34Selenocompound metabolism_Homo sapiens_hsa004501.45155664
35Carbon metabolism_Homo sapiens_hsa012001.44901713
36Cell cycle_Homo sapiens_hsa041101.42926611
37Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.42392617
38Biosynthesis of amino acids_Homo sapiens_hsa012301.39371379
39Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.38667360
40Fatty acid elongation_Homo sapiens_hsa000621.38637169
41Systemic lupus erythematosus_Homo sapiens_hsa053221.33395658
42Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.32645379
43Measles_Homo sapiens_hsa051621.29844826
44RNA degradation_Homo sapiens_hsa030181.29729029
45Arachidonic acid metabolism_Homo sapiens_hsa005901.28168206
46Steroid hormone biosynthesis_Homo sapiens_hsa001401.25433861
47Herpes simplex infection_Homo sapiens_hsa051681.24673811
48Huntingtons disease_Homo sapiens_hsa050161.23256601
49Glutathione metabolism_Homo sapiens_hsa004801.21083036
50Graft-versus-host disease_Homo sapiens_hsa053321.20639641
51Asthma_Homo sapiens_hsa053101.19850713
52RNA polymerase_Homo sapiens_hsa030201.19661568
53Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.18956302
54Autoimmune thyroid disease_Homo sapiens_hsa053201.17534416
55Purine metabolism_Homo sapiens_hsa002301.16611821
56Allograft rejection_Homo sapiens_hsa053301.16340751
57Folate biosynthesis_Homo sapiens_hsa007901.13738959
58Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.12638355
59mRNA surveillance pathway_Homo sapiens_hsa030151.10636677
60ABC transporters_Homo sapiens_hsa020101.08604377
61Nicotine addiction_Homo sapiens_hsa050331.08368603
62Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.05438326
63Linoleic acid metabolism_Homo sapiens_hsa005911.04906886
64RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.01131122
65Transcriptional misregulation in cancer_Homo sapiens_hsa052021.00911539
66Sphingolipid metabolism_Homo sapiens_hsa006000.99174625
67Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.98600089
68p53 signaling pathway_Homo sapiens_hsa041150.98327534
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.96433789
70Vitamin digestion and absorption_Homo sapiens_hsa049770.94990397
71Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.90922977
72Ether lipid metabolism_Homo sapiens_hsa005650.90309716
73Ribosome_Homo sapiens_hsa030100.89131806
74Sulfur metabolism_Homo sapiens_hsa009200.88991520
75TGF-beta signaling pathway_Homo sapiens_hsa043500.86171995
76RNA transport_Homo sapiens_hsa030130.84411084
77Lysine degradation_Homo sapiens_hsa003100.84022321
78Taste transduction_Homo sapiens_hsa047420.80998587
79Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.80024736
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.78987975
81Alzheimers disease_Homo sapiens_hsa050100.78613552
82Thyroid cancer_Homo sapiens_hsa052160.76875967
83Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.74500244
84Oocyte meiosis_Homo sapiens_hsa041140.74417987
85NOD-like receptor signaling pathway_Homo sapiens_hsa046210.71738838
86Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.71411185
87Retinol metabolism_Homo sapiens_hsa008300.71376652
88Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.70353355
89Fatty acid degradation_Homo sapiens_hsa000710.70253382
90Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.69732048
91Pentose phosphate pathway_Homo sapiens_hsa000300.68348295
92Influenza A_Homo sapiens_hsa051640.67406401
93Pentose and glucuronate interconversions_Homo sapiens_hsa000400.66793672
94N-Glycan biosynthesis_Homo sapiens_hsa005100.65335715
95Basal cell carcinoma_Homo sapiens_hsa052170.64858977
96Fatty acid metabolism_Homo sapiens_hsa012120.62948072
97Caffeine metabolism_Homo sapiens_hsa002320.61198224
98Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.61114932
99Peroxisome_Homo sapiens_hsa041460.60570291
100Jak-STAT signaling pathway_Homo sapiens_hsa046300.58866567
101beta-Alanine metabolism_Homo sapiens_hsa004100.57427271
102Arginine and proline metabolism_Homo sapiens_hsa003300.56536219
103Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.55158115
104Other glycan degradation_Homo sapiens_hsa005110.55092151
105Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54130931
106Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.53653176
107Hippo signaling pathway_Homo sapiens_hsa043900.53347626
108Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52899860
109Toll-like receptor signaling pathway_Homo sapiens_hsa046200.52199534
110Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.51197541
111Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51125599
112Histidine metabolism_Homo sapiens_hsa003400.50762510
113Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.49591893
114Butanoate metabolism_Homo sapiens_hsa006500.49043730
115Malaria_Homo sapiens_hsa051440.48933058
116Tight junction_Homo sapiens_hsa045300.48839306
117Steroid biosynthesis_Homo sapiens_hsa001000.48635710
118Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48629420
119Galactose metabolism_Homo sapiens_hsa000520.47536302
120Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.47307108
121Epstein-Barr virus infection_Homo sapiens_hsa051690.46866146
122Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.46773202
123Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.45386590
124Tryptophan metabolism_Homo sapiens_hsa003800.44686590
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.44473621
126Ovarian steroidogenesis_Homo sapiens_hsa049130.43180197
127Staphylococcus aureus infection_Homo sapiens_hsa051500.43117757
128Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.42833348
129B cell receptor signaling pathway_Homo sapiens_hsa046620.42180498
130African trypanosomiasis_Homo sapiens_hsa051430.40330273
131Primary bile acid biosynthesis_Homo sapiens_hsa001200.38919988
132HTLV-I infection_Homo sapiens_hsa051660.37825492
133Viral carcinogenesis_Homo sapiens_hsa052030.37758369
134Inositol phosphate metabolism_Homo sapiens_hsa005620.37502757
135Phosphatidylinositol signaling system_Homo sapiens_hsa040700.36961825
136Drug metabolism - other enzymes_Homo sapiens_hsa009830.36663024
137Calcium signaling pathway_Homo sapiens_hsa040200.36566917
138Vibrio cholerae infection_Homo sapiens_hsa051100.36036721
139Adherens junction_Homo sapiens_hsa045200.34839476
140Morphine addiction_Homo sapiens_hsa050320.34834366
141Collecting duct acid secretion_Homo sapiens_hsa049660.33821585
142Vitamin B6 metabolism_Homo sapiens_hsa007500.32220294
143Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.32202764
144Regulation of autophagy_Homo sapiens_hsa041400.31687927
145SNARE interactions in vesicular transport_Homo sapiens_hsa041300.30995675
146Leishmaniasis_Homo sapiens_hsa051400.30534870
147Small cell lung cancer_Homo sapiens_hsa052220.30302401
148Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.29796976
149Alcoholism_Homo sapiens_hsa050340.29718869
150T cell receptor signaling pathway_Homo sapiens_hsa046600.29257199
151Legionellosis_Homo sapiens_hsa051340.28973121
152Notch signaling pathway_Homo sapiens_hsa043300.27911950
153Metabolic pathways_Homo sapiens_hsa011000.27862300
154Rheumatoid arthritis_Homo sapiens_hsa053230.27582694
155MicroRNAs in cancer_Homo sapiens_hsa052060.26564819
156Wnt signaling pathway_Homo sapiens_hsa043100.26144402
157Glycosaminoglycan degradation_Homo sapiens_hsa005310.25520796
158Chemical carcinogenesis_Homo sapiens_hsa052040.24373015
159Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.23866725
160Starch and sucrose metabolism_Homo sapiens_hsa005000.21547937
161Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.21454477
162Hedgehog signaling pathway_Homo sapiens_hsa043400.16613749
163Sulfur relay system_Homo sapiens_hsa041220.12703571

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