ARPC4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* Arp2/3 complex-mediated actin nucleation (GO:0034314)4.47437670
2negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.40136590
3negative regulation of cell killing (GO:0031342)4.40136590
4neutrophil activation involved in immune response (GO:0002283)4.29595249
5negative regulation of interleukin-12 production (GO:0032695)3.93526121
6sequestering of actin monomers (GO:0042989)3.88559389
7ribosomal small subunit assembly (GO:0000028)3.87224195
8detection of other organism (GO:0098543)3.74549131
9immunoglobulin mediated immune response (GO:0016064)3.74301849
10detection of bacterium (GO:0016045)3.67956320
11respiratory burst (GO:0045730)3.66917002
12antigen processing and presentation of endogenous antigen (GO:0019883)3.57890043
13B cell mediated immunity (GO:0019724)3.51040685
14antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.45487755
15antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.45487755
16antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.39144231
17response to peptidoglycan (GO:0032494)3.34184809
18regulation of B cell receptor signaling pathway (GO:0050855)3.31528424
19negative regulation of phagocytosis (GO:0050765)3.26050535
20regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.21321085
21* actin nucleation (GO:0045010)3.16968909
22leukocyte aggregation (GO:0070486)3.16790945
23amino sugar catabolic process (GO:0046348)3.13332567
24regulation of protein heterodimerization activity (GO:0043497)3.10067246
25antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.08689058
26neutrophil activation (GO:0042119)3.06869887
27positive regulation of interferon-alpha production (GO:0032727)3.05756975
28regulation of mast cell degranulation (GO:0043304)3.05423163
29regulation of dendritic cell antigen processing and presentation (GO:0002604)3.04466353
30positive regulation of gamma-delta T cell activation (GO:0046645)3.03759340
31detection of external biotic stimulus (GO:0098581)3.03023847
32viral transcription (GO:0019083)3.00887034
33modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.00066821
34positive regulation by organism of defense response of other organism involved in symbiotic interact3.00066821
35modulation by symbiont of host immune response (GO:0052553)3.00066821
36positive regulation by symbiont of host defense response (GO:0052509)3.00066821
37modulation by symbiont of host defense response (GO:0052031)3.00066821
38modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.00066821
39positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.99693647
40regulation of gamma-delta T cell activation (GO:0046643)2.99542422
41regulation of T cell tolerance induction (GO:0002664)2.98196553
42positive thymic T cell selection (GO:0045059)2.97104488
43antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.97092660
44granulocyte activation (GO:0036230)2.95556440
45cellular response to zinc ion (GO:0071294)2.95353886
46regulation of interferon-alpha production (GO:0032647)2.91646881
47myeloid dendritic cell activation (GO:0001773)2.90535453
48translational termination (GO:0006415)2.88716278
49NIK/NF-kappaB signaling (GO:0038061)2.86292408
50hepatocyte apoptotic process (GO:0097284)2.86069292
51response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.83605366
52response to host immune response (GO:0052572)2.83605366
53natural killer cell mediated immunity (GO:0002228)2.81616213
54natural killer cell mediated cytotoxicity (GO:0042267)2.81616213
55positive regulation of antigen processing and presentation (GO:0002579)2.81599040
56T cell apoptotic process (GO:0070231)2.81440195
57DNA strand elongation involved in DNA replication (GO:0006271)2.79280376
58regulation of leukocyte degranulation (GO:0043300)2.79066805
59DNA deamination (GO:0045006)2.78386838
60positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.78187870
61telomere maintenance via semi-conservative replication (GO:0032201)2.76867886
62antigen processing and presentation via MHC class Ib (GO:0002475)2.76021800
63positive regulation of lamellipodium assembly (GO:0010592)2.75849427
64negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.74894272
65interferon-gamma-mediated signaling pathway (GO:0060333)2.74765891
66cellular response to interferon-beta (GO:0035458)2.73885261
67regulation of mast cell activation involved in immune response (GO:0033006)2.73222255
68regulation of myeloid leukocyte mediated immunity (GO:0002886)2.71103788
69leukocyte degranulation (GO:0043299)2.69316442
70positive regulation of mast cell activation (GO:0033005)2.68788368
71formation of translation preinitiation complex (GO:0001731)2.68728970
72negative regulation of leukocyte mediated immunity (GO:0002704)2.68253484
73response to muramyl dipeptide (GO:0032495)2.68244958
74barbed-end actin filament capping (GO:0051016)2.67844454
75positive regulation of monocyte chemotaxis (GO:0090026)2.67327813
76response to interferon-beta (GO:0035456)2.65733293
77myeloid dendritic cell differentiation (GO:0043011)2.64748143
78cellular extravasation (GO:0045123)2.64680997
79regulation of natural killer cell mediated immunity (GO:0002715)2.64665629
80regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.64665629
81regulation of antigen processing and presentation (GO:0002577)2.64566754
82translational elongation (GO:0006414)2.64021110
83positive regulation of macrophage differentiation (GO:0045651)2.63977315
84DNA strand elongation (GO:0022616)2.63956692
85reactive oxygen species biosynthetic process (GO:1903409)2.63258322
86regulation of tolerance induction (GO:0002643)2.62835655
87regulation of interferon-beta biosynthetic process (GO:0045357)2.62734471
88positive regulation of T cell mediated cytotoxicity (GO:0001916)2.60713784
89hydrogen peroxide biosynthetic process (GO:0050665)2.60260685
90regulation of T cell mediated cytotoxicity (GO:0001914)2.59659577
91detection of biotic stimulus (GO:0009595)2.59519390
92SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.59500062
93lymphocyte chemotaxis (GO:0048247)2.59119689
94negative regulation of cytokine production involved in immune response (GO:0002719)2.58855578
95pinocytosis (GO:0006907)2.58845904
96regulation of mast cell activation (GO:0033003)2.58657496
97response to interleukin-15 (GO:0070672)2.58350249
98leukocyte mediated cytotoxicity (GO:0001909)2.58201176
99cellular response to interferon-gamma (GO:0071346)2.58168721
100regulation of gamma-delta T cell differentiation (GO:0045586)2.58045678
101regulation of lymphocyte migration (GO:2000401)2.57871623
102myeloid cell activation involved in immune response (GO:0002275)2.57081869
103response to host (GO:0075136)2.56692415
104response to host defenses (GO:0052200)2.56692415
105response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.56692415
106negative regulation of innate immune response (GO:0045824)2.55539360
107regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.55528133
108positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.55005255
109negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.54618033
110regulation of B cell differentiation (GO:0045577)2.54161554
111positive regulation of B cell differentiation (GO:0045579)2.53810992
112telomere maintenance via recombination (GO:0000722)2.53092883
113positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.52256856
114detection of molecule of bacterial origin (GO:0032490)2.52089655
115regulation of defense response to virus by virus (GO:0050690)2.51485202
116ribosomal large subunit biogenesis (GO:0042273)2.51348510
117macrophage activation (GO:0042116)2.50518111
118germinal center formation (GO:0002467)2.50126041
119phagosome maturation (GO:0090382)2.50033940
120regulation of T-helper 1 cell differentiation (GO:0045625)2.49993485
121protein targeting to ER (GO:0045047)2.49930831
122response to interferon-gamma (GO:0034341)2.49849462
123lymphocyte mediated immunity (GO:0002449)2.49380116
124cotranslational protein targeting to membrane (GO:0006613)2.49104780
125T cell migration (GO:0072678)2.46484473
126cellular response to type I interferon (GO:0071357)2.44778484
127type I interferon signaling pathway (GO:0060337)2.44778484
128mast cell activation (GO:0045576)2.44219913
129negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.44140820
130ribosomal small subunit biogenesis (GO:0042274)2.43001730
131production of molecular mediator involved in inflammatory response (GO:0002532)2.42779471
132antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.42758834
133translational initiation (GO:0006413)2.42520422
134B cell receptor signaling pathway (GO:0050853)2.41563398
135viral life cycle (GO:0019058)2.41518255
136lymphocyte apoptotic process (GO:0070227)2.41354433
137response to type I interferon (GO:0034340)2.41027068
138negative thymic T cell selection (GO:0045060)2.39944034
139negative regulation of myeloid cell apoptotic process (GO:0033033)2.38611929
140superoxide anion generation (GO:0042554)2.37760133
141lipopolysaccharide-mediated signaling pathway (GO:0031663)2.37130344
142DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.36192519
143response to protozoan (GO:0001562)2.35901122
144protein localization to endoplasmic reticulum (GO:0070972)2.35796682
145defense response to protozoan (GO:0042832)2.35169054
146positive regulation of lamellipodium organization (GO:1902745)2.34775252
147nucleobase-containing small molecule interconversion (GO:0015949)2.32425164
148establishment of protein localization to endoplasmic reticulum (GO:0072599)2.32035533
149macrophage activation involved in immune response (GO:0002281)2.31835204
150leukocyte cell-cell adhesion (GO:0007159)2.31090248
151intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.30646839

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.75405184
2IRF8_21731497_ChIP-ChIP_J774_Mouse3.77320532
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.46042647
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.27396551
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.05272698
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.78201165
7* SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.62602904
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.53128093
9MYC_18555785_ChIP-Seq_MESCs_Mouse2.52477872
10SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.45356391
11BP1_19119308_ChIP-ChIP_Hs578T_Human2.36820378
12MYB_21317192_ChIP-Seq_ERMYB_Mouse2.28972042
13FOXM1_23109430_ChIP-Seq_U2OS_Human2.26224764
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.21055626
15* IRF8_27001747_Chip-Seq_BMDM_Mouse2.11528052
16VDR_21846776_ChIP-Seq_THP-1_Human2.10751256
17MYC_22102868_ChIP-Seq_BL_Human2.09419711
18* SPI1_23547873_ChIP-Seq_NB4_Human2.09299805
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.08491221
20STAT4_19710469_ChIP-ChIP_TH1__Mouse2.05849640
21FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.04707296
22E2F4_17652178_ChIP-ChIP_JURKAT_Human2.03492167
23SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.02961772
24* FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.02956521
25GABP_17652178_ChIP-ChIP_JURKAT_Human2.02766868
26EST1_17652178_ChIP-ChIP_JURKAT_Human2.01534989
27SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.99669976
28STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.99471041
29NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.98054497
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.95058719
31KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.92234580
32* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.91127840
33FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.90019020
34MYC_18358816_ChIP-ChIP_MESCs_Mouse1.84853780
35CREB1_15753290_ChIP-ChIP_HEK293T_Human1.84822117
36TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.83744336
37* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.79690276
38ETS1_20019798_ChIP-Seq_JURKAT_Human1.79410938
39MYC_19079543_ChIP-ChIP_MESCs_Mouse1.75546450
40RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.74140532
41* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.69950716
42* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.68002084
43MAF_26560356_Chip-Seq_TH1_Human1.66525200
44XRN2_22483619_ChIP-Seq_HELA_Human1.66508329
45LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.65100877
46VDR_24763502_ChIP-Seq_THP-1_Human1.64734546
47MYB_26560356_Chip-Seq_TH2_Human1.64169795
48LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.63972143
49* VDR_23849224_ChIP-Seq_CD4+_Human1.63331989
50BRD4_27068464_Chip-Seq_AML-cells_Mouse1.62314076
51Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.60355254
52IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.58508490
53LXR_22292898_ChIP-Seq_THP-1_Human1.58394844
54NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.55847980
55RUNX1_22412390_ChIP-Seq_EML_Mouse1.53272205
56NELFA_20434984_ChIP-Seq_ESCs_Mouse1.53065599
57RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.52748140
58HOXB4_20404135_ChIP-ChIP_EML_Mouse1.49800914
59RUNX_20019798_ChIP-Seq_JUKART_Human1.49312775
60STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.47779344
61DCP1A_22483619_ChIP-Seq_HELA_Human1.47689208
62THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.44171068
63MYB_26560356_Chip-Seq_TH1_Human1.43169751
64UTX_26944678_Chip-Seq_JUKART_Human1.38665166
65FOXP3_21729870_ChIP-Seq_TREG_Human1.37587195
66GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.36299515
67* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.35174354
68TFEB_21752829_ChIP-Seq_HELA_Human1.33208543
69PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.32322198
70MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.31912705
71* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.31384997
72SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.30664889
73* ELK1_19687146_ChIP-ChIP_HELA_Human1.29947415
74KDM2B_26808549_Chip-Seq_SUP-B15_Human1.28045032
75RARG_19884340_ChIP-ChIP_MEFs_Mouse1.27111471
76STAT6_21828071_ChIP-Seq_BEAS2B_Human1.26527782
77PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.26518804
78GABP_19822575_ChIP-Seq_HepG2_Human1.26353195
79HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.24251691
80CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.23746292
81BCL6_27268052_Chip-Seq_Bcells_Human1.23407918
82CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.22106387
83KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.21026279
84NOTCH1_21737748_ChIP-Seq_TLL_Human1.21017795
85MAF_26560356_Chip-Seq_TH2_Human1.20882876
86CIITA_25753668_ChIP-Seq_RAJI_Human1.20702430
87TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.20577416
88GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.19830191
89GATA1_19941827_ChIP-Seq_MEL_Mouse1.19723193
90TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.19602952
91VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.19018097
92CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.18091881
93ELF1_20517297_ChIP-Seq_JURKAT_Human1.17121768
94TTF2_22483619_ChIP-Seq_HELA_Human1.16959989
95E2F1_21310950_ChIP-Seq_MCF-7_Human1.16188942
96* BCOR_27268052_Chip-Seq_Bcells_Human1.15657314
97GATA3_27048872_Chip-Seq_THYMUS_Human1.14957862
98SCL_19346495_ChIP-Seq_HPC-7_Human1.13869967
99* ELK3_25401928_ChIP-Seq_HUVEC_Human1.13579961
100PU.1_20513432_ChIP-Seq_Bcells_Mouse1.12810622
101RACK7_27058665_Chip-Seq_MCF-7_Human1.12375501
102* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.11698229
103CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.11304113
104KDM2B_26808549_Chip-Seq_DND41_Human1.11262947
105GATA2_21666600_ChIP-Seq_HMVEC_Human1.10033199
106CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09003981
107VDR_24787735_ChIP-Seq_THP-1_Human1.08952021
108CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.08703842
109SPI1_23127762_ChIP-Seq_K562_Human1.07527612
110GATA2_22383799_ChIP-Seq_G1ME_Mouse1.07182952
111PU_27001747_Chip-Seq_BMDM_Mouse1.06081844
112PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.06046519
113TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05770274
114NANOG_18555785_ChIP-Seq_MESCs_Mouse1.05624197
115PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05170509
116CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.04939337
117SRY_22984422_ChIP-ChIP_TESTIS_Rat1.04880311
118SRF_21415370_ChIP-Seq_HL-1_Mouse1.03808428
119HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.03488018
120TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.03353376
121TP63_17297297_ChIP-ChIP_HaCaT_Human1.03021572
122GATA1_22383799_ChIP-Seq_G1ME_Mouse1.01939042
123POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.01647343
124STAT3_1855785_ChIP-Seq_MESCs_Mouse1.01510994
125YY1_21170310_ChIP-Seq_MESCs_Mouse1.01396644
126HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.00484952
127PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00413329
128FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.00395390
129E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.99706977
130MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.98955005
131STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.98745575
132NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.97626050
133CTCF_27219007_Chip-Seq_ERYTHROID_Human0.97622297
134SMAD_19615063_ChIP-ChIP_OVARY_Human0.97581529
135TCF7_22412390_ChIP-Seq_EML_Mouse0.96711600
136KDM5A_27292631_Chip-Seq_BREAST_Human0.96406036
137* GATA3_26560356_Chip-Seq_TH2_Human0.94536028
138IKZF1_21737484_ChIP-ChIP_HCT116_Human0.91655509
139NCOR1_26117541_ChIP-Seq_K562_Human0.90881999
140GATA1_19941826_ChIP-Seq_K562_Human0.89608961
141CTCF_26484167_Chip-Seq_Bcells_Mouse0.88445109
142KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.87344931

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.20126627
2MP0003436_decreased_susceptibility_to3.41050575
3MP0003303_peritoneal_inflammation3.06740358
4MP0009785_altered_susceptibility_to3.03705425
5MP0002148_abnormal_hypersensitivity_rea3.03204061
6MP0000685_abnormal_immune_system2.80916859
7MP0005000_abnormal_immune_tolerance2.75082452
8MP0005671_abnormal_response_to2.72783099
9MP0002419_abnormal_innate_immunity2.59011784
10MP0002452_abnormal_antigen_presenting2.55254007
11MP0005025_abnormal_response_to2.55111138
12MP0001800_abnormal_humoral_immune2.50128014
13MP0005387_immune_system_phenotype2.40797017
14MP0001790_abnormal_immune_system2.40797017
15MP0001819_abnormal_immune_cell2.36864647
16MP0002420_abnormal_adaptive_immunity2.36621438
17MP0002723_abnormal_immune_serum2.31768982
18MP0009333_abnormal_splenocyte_physiolog2.31377856
19MP0006082_CNS_inflammation2.22570001
20MP0003724_increased_susceptibility_to2.21849147
21MP0003693_abnormal_embryo_hatching2.18871447
22MP0002398_abnormal_bone_marrow2.07373946
23MP0002405_respiratory_system_inflammati2.07087008
24MP0003763_abnormal_thymus_physiology2.05303232
25MP0002396_abnormal_hematopoietic_system1.94466445
26MP0000858_altered_metastatic_potential1.93779899
27MP0000716_abnormal_immune_system1.90271102
28MP0005464_abnormal_platelet_physiology1.88626074
29MP0001853_heart_inflammation1.80034141
30MP0001533_abnormal_skeleton_physiology1.78653632
31MP0000689_abnormal_spleen_morphology1.77772662
32MP0005058_abnormal_lysosome_morphology1.77414277
33MP0002166_altered_tumor_susceptibility1.74472907
34MP0002722_abnormal_immune_system1.72152666
35MP0008007_abnormal_cellular_replicative1.70906806
36MP0005397_hematopoietic_system_phenotyp1.70801198
37MP0001545_abnormal_hematopoietic_system1.70801198
38MP0003806_abnormal_nucleotide_metabolis1.70536944
39MP0002006_tumorigenesis1.69612299
40MP0002429_abnormal_blood_cell1.67863051
41MP0004808_abnormal_hematopoietic_stem1.67179925
42MP0000490_abnormal_crypts_of1.64263875
43MP0010155_abnormal_intestine_physiology1.62326254
44MP0001845_abnormal_inflammatory_respons1.61774197
45MP0003448_altered_tumor_morphology1.61313553
46MP0004957_abnormal_blastocyst_morpholog1.56264179
47MP0008260_abnormal_autophagy1.53767446
48MP0004510_myositis1.51726526
49MP0003077_abnormal_cell_cycle1.50030947
50MP0005451_abnormal_body_composition1.49921778
51MP0004947_skin_inflammation1.47067816
52MP0003111_abnormal_nucleus_morphology1.46057651
53MP0000343_altered_response_to1.42958623
54MP0010094_abnormal_chromosome_stability1.39000460
55MP0010307_abnormal_tumor_latency1.34430107
56MP0005310_abnormal_salivary_gland1.33329022
57MP0010352_gastrointestinal_tract_polyps1.33166744
58MP0000604_amyloidosis1.32141658
59MP0000703_abnormal_thymus_morphology1.30064851
60MP0009278_abnormal_bone_marrow1.23910193
61MP0003186_abnormal_redox_activity1.23878509
62MP0008469_abnormal_protein_level1.20935269
63MP0003566_abnormal_cell_adhesion1.20802001
64MP0010234_abnormal_vibrissa_follicle1.19221425
65MP0002019_abnormal_tumor_incidence1.17780351
66MP0006054_spinal_hemorrhage1.09698251
67MP0002933_joint_inflammation1.08589980
68MP0005076_abnormal_cell_differentiation1.07981280
69MP0005023_abnormal_wound_healing1.06121839
70MP0003172_abnormal_lysosome_physiology1.04954685
71MP0003866_abnormal_defecation1.04829713
72MP0000465_gastrointestinal_hemorrhage1.03898210
73MP0005174_abnormal_tail_pigmentation1.03648756
74MP0003300_gastrointestinal_ulcer1.02916720
75MP0005165_increased_susceptibility_to1.01066960
76MP0002254_reproductive_system_inflammat0.99406620
77MP0005075_abnormal_melanosome_morpholog0.98816398
78MP0001873_stomach_inflammation0.98464432
79MP0008438_abnormal_cutaneous_collagen0.97470230
80MP0005390_skeleton_phenotype0.95031625
81MP0009763_increased_sensitivity_to0.94229501
82MP0000313_abnormal_cell_death0.94009765
83MP0009840_abnormal_foam_cell0.93758725
84MP0002998_abnormal_bone_remodeling0.93220771
85MP0002877_abnormal_melanocyte_morpholog0.91071756
86MP0000350_abnormal_cell_proliferation0.90356401
87MP0002138_abnormal_hepatobiliary_system0.89884538
88MP0008932_abnormal_embryonic_tissue0.89804392
89MP0004883_abnormal_blood_vessel0.89267541
90MP0009764_decreased_sensitivity_to0.88519220
91MP0001542_abnormal_bone_strength0.88492944
92MP0004381_abnormal_hair_follicle0.87385829
93MP0003828_pulmonary_edema0.86339322
94MP0003795_abnormal_bone_structure0.85963230
95MP0002132_abnormal_respiratory_system0.83903206
96MP0003453_abnormal_keratinocyte_physiol0.82707155
97MP0008058_abnormal_DNA_repair0.82618893
98MP0008057_abnormal_DNA_replication0.82608669
99MP0003279_aneurysm0.81645563
100MP0001348_abnormal_lacrimal_gland0.81185729
101MP0000015_abnormal_ear_pigmentation0.79700738
102MP0005164_abnormal_response_to0.79578302
103MP0004782_abnormal_surfactant_physiolog0.79329361
104MP0002277_abnormal_respiratory_mucosa0.78652113
105MP0003075_altered_response_to0.78286238
106MP0008004_abnormal_stomach_pH0.77984955
107MP0002163_abnormal_gland_morphology0.76869492
108MP0001663_abnormal_digestive_system0.75514915
109MP0003786_premature_aging0.75050806
110MP0001851_eye_inflammation0.73056194
111MP0003183_abnormal_peptide_metabolism0.72650442
112MP0003045_fibrosis0.70946860
113MP0000249_abnormal_blood_vessel0.70260233
114MP0005166_decreased_susceptibility_to0.70175209
115MP0005167_abnormal_blood-brain_barrier0.69568253
116MP0003191_abnormal_cellular_cholesterol0.68363173
117MP0009379_abnormal_foot_pigmentation0.68129317
118MP0001915_intracranial_hemorrhage0.67842837
119MP0002139_abnormal_hepatobiliary_system0.67837929
120MP0001849_ear_inflammation0.66426316
121MP0003091_abnormal_cell_migration0.65894215
122MP0008874_decreased_physiological_sensi0.65864105
123MP0005319_abnormal_enzyme/_coenzyme0.64481844
124MP0002693_abnormal_pancreas_physiology0.63982929
125MP0003329_amyloid_beta_deposits0.63594284

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.75681825
2Eczematoid dermatitis (HP:0000976)5.46425773
3Recurrent bacterial skin infections (HP:0005406)4.96288549
4Elevated erythrocyte sedimentation rate (HP:0003565)4.30893169
5Chronic obstructive pulmonary disease (HP:0006510)3.74801790
6Obstructive lung disease (HP:0006536)3.74801790
7Myositis (HP:0100614)3.73327588
8Mediastinal lymphadenopathy (HP:0100721)3.70155047
9Abnormality of macrophages (HP:0004311)3.69207088
10Autoimmune thrombocytopenia (HP:0001973)3.60499642
11Recurrent gram-negative bacterial infections (HP:0005420)3.59131359
12Thrombocytosis (HP:0001894)3.53109655
13Recurrent fungal infections (HP:0002841)3.48553321
14Cellulitis (HP:0100658)3.41783621
15Vacuolated lymphocytes (HP:0001922)3.22630205
16Recurrent viral infections (HP:0004429)3.20377296
17Recurrent skin infections (HP:0001581)3.14869486
18Petechiae (HP:0000967)3.08032806
19Purpura (HP:0000979)3.06814776
20Meningitis (HP:0001287)3.01090678
21IgM deficiency (HP:0002850)2.95916552
22Chronic otitis media (HP:0000389)2.88409910
23Abnormal delayed hypersensitivity skin test (HP:0002963)2.88267079
24Loss of speech (HP:0002371)2.87865077
25Poor head control (HP:0002421)2.83832763
26Abnormality of T cell physiology (HP:0011840)2.82481859
27Orchitis (HP:0100796)2.81462623
28Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.81089222
29Increased IgM level (HP:0003496)2.79200464
30Vasculitis (HP:0002633)2.73325446
31Prolonged bleeding time (HP:0003010)2.71858208
32Abnormality of the anterior horn cell (HP:0006802)2.71368494
33Degeneration of anterior horn cells (HP:0002398)2.71368494
34Agnosia (HP:0010524)2.68381411
35Vertebral compression fractures (HP:0002953)2.67728679
36Eosinophilia (HP:0001880)2.67715315
37Abnormality of T cells (HP:0002843)2.66455330
38Abnormality of polysaccharide metabolism (HP:0011012)2.66198736
39Abnormality of glycosaminoglycan metabolism (HP:0004371)2.66198736
40Abnormality of mucopolysaccharide metabolism (HP:0011020)2.66198736
41Stomatitis (HP:0010280)2.66194520
42Pustule (HP:0200039)2.64868745
43Basal ganglia calcification (HP:0002135)2.63340139
44Gingivitis (HP:0000230)2.61788909
45Periodontitis (HP:0000704)2.61764420
46Leukocytosis (HP:0001974)2.59449858
47Increased IgE level (HP:0003212)2.58050694
48Urticaria (HP:0001025)2.56352071
49Recurrent cutaneous fungal infections (HP:0011370)2.55961329
50Chronic mucocutaneous candidiasis (HP:0002728)2.55961329
51Granulocytopenia (HP:0001913)2.54576001
52Interstitial pulmonary disease (HP:0006530)2.54284646
53Increased cerebral lipofuscin (HP:0011813)2.53253130
54Gastrointestinal infarctions (HP:0005244)2.52942423
55Urinary glycosaminoglycan excretion (HP:0003541)2.50792536
56Mucopolysacchariduria (HP:0008155)2.50792536
57Optic neuritis (HP:0100653)2.50553210
58Retrobulbar optic neuritis (HP:0100654)2.50553210
59Chest pain (HP:0100749)2.49449953
60Epistaxis (HP:0000421)2.49193481
61Increased neuronal autofluorescent lipopigment (HP:0002074)2.48081778
62Hypergammaglobulinemia (HP:0010702)2.47983625
63Osteomyelitis (HP:0002754)2.46596215
64Abnormality of cells of the lymphoid lineage (HP:0012140)2.46033056
65Abnormality of T cell number (HP:0011839)2.45747069
66Reticulocytopenia (HP:0001896)2.45706014
67Abnormality of liposaccharide metabolism (HP:0010968)2.45698276
68Abnormality of glycosphingolipid metabolism (HP:0004343)2.45698276
69Abnormality of glycolipid metabolism (HP:0010969)2.45698276
70Abnormal number of erythroid precursors (HP:0012131)2.43095619
71Agammaglobulinemia (HP:0004432)2.41830369
72Abnormality of cells of the erythroid lineage (HP:0012130)2.40419417
73Progressive neurologic deterioration (HP:0002344)2.40260849
74Increased serum ferritin (HP:0003281)2.39921345
75Recurrent bronchitis (HP:0002837)2.36304562
76Systemic lupus erythematosus (HP:0002725)2.32049069
77Recurrent lower respiratory tract infections (HP:0002783)2.25987188
78Lymphopenia (HP:0001888)2.25981982
79Recurrent pneumonia (HP:0006532)2.25507705
80Hematochezia (HP:0002573)2.24885894
81Gingival bleeding (HP:0000225)2.24849282
82Abnormality of eosinophils (HP:0001879)2.24127856
83Amyloidosis (HP:0011034)2.23957979
84Panhypogammaglobulinemia (HP:0003139)2.19263295
85Spontaneous hematomas (HP:0007420)2.16535111
86T lymphocytopenia (HP:0005403)2.11439549
87Episodic fever (HP:0001954)2.10345642
88Skin ulcer (HP:0200042)2.09453644
89Pulmonary fibrosis (HP:0002206)2.06326149
90Pulmonary infiltrates (HP:0002113)2.06274206
91Abnormality of iron homeostasis (HP:0011031)2.03344217
92Arterial thrombosis (HP:0004420)2.03206753
93IgG deficiency (HP:0004315)2.00606398
94Papilloma (HP:0012740)1.97829675
95Verrucae (HP:0200043)1.97829675
96Premature loss of primary teeth (HP:0006323)1.95915259
97Hypertensive crisis (HP:0100735)1.95735846
98Restrictive lung disease (HP:0002091)1.95372879
99Gastrointestinal inflammation (HP:0004386)1.94223330
100Abnormality of the prostate (HP:0008775)1.92948594
101Myocardial infarction (HP:0001658)1.92892964
102Keratoconjunctivitis sicca (HP:0001097)1.92871213
103Osteolytic defects of the phalanges of the hand (HP:0009771)1.92661226
104Osteolytic defects of the hand bones (HP:0009699)1.92661226
105Lymphoma (HP:0002665)1.92600565
106Chronic diarrhea (HP:0002028)1.92101765
107Axonal loss (HP:0003447)1.90303998
108Anorexia (HP:0002039)1.89661837
109Inflammation of the large intestine (HP:0002037)1.89442366
110Dysostosis multiplex (HP:0000943)1.89233509
111Aplasia/Hypoplasia of the sacrum (HP:0008517)1.86971275
112Hepatosplenomegaly (HP:0001433)1.86799815
113Malnutrition (HP:0004395)1.85697421
114Nasal polyposis (HP:0100582)1.84977305
115Arthralgia (HP:0002829)1.84528272
116Pulmonary embolism (HP:0002204)1.83283365
117Encephalitis (HP:0002383)1.83174255
118Mutism (HP:0002300)1.82993837
119Hemoptysis (HP:0002105)1.82891598
120Sepsis (HP:0100806)1.82891034
121Pallor (HP:0000980)1.82131835
122IgA deficiency (HP:0002720)1.81822175
123Syringomyelia (HP:0003396)1.81701656
124Spinal cord lesions (HP:0100561)1.81701656
125Diminished motivation (HP:0000745)1.80913286
126Colitis (HP:0002583)1.80670060
127Disinhibition (HP:0000734)1.79629825
128Autoimmune hemolytic anemia (HP:0001890)1.79487686
129Abnormality of the nasal mucosa (HP:0000433)1.79008127
130Combined immunodeficiency (HP:0005387)1.77542440
131Gastrointestinal stroma tumor (HP:0100723)1.76522305
132Amaurosis fugax (HP:0100576)1.75847800

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BLK3.39045350
2PIM23.11703810
3MAP4K12.96288385
4TESK22.88120365
5MAP3K142.68732712
6NME22.66016782
7EIF2AK12.62847804
8IRAK42.51890481
9BUB12.27283572
10TBK12.25356251
11TESK12.16836643
12MAP3K32.09627263
13SMG11.94601117
14JAK31.92311890
15TLK11.91808938
16PRPF4B1.91749162
17IKBKE1.90797671
18ZAP701.81482739
19TYK21.80944567
20IKBKB1.80927396
21TXK1.74683923
22KIT1.69005076
23RIPK41.67940752
24STK101.67474427
25NEK91.66981604
26RPS6KA41.64745207
27PIM11.55363439
28VRK21.52955302
29IRAK31.47520035
30KDR1.47034985
31BTK1.44338677
32SCYL21.42763033
33LRRK21.41649106
34WEE11.41236397
35TAOK11.41220254
36MAP3K111.39534188
37SYK1.34900023
38TNK21.33146395
39FGR1.25856793
40ARAF1.24299335
41CSF1R1.23651645
42EPHB11.23014446
43TEC1.22415988
44LIMK11.20433767
45PAK41.15819908
46CLK11.15141018
47MAP2K31.13868025
48EIF2AK31.13055257
49CSK1.11856197
50ERN11.08668860
51MAP3K11.08126777
52STK41.07812758
53LYN1.00235561
54FES0.97777160
55CHUK0.95722419
56MAP3K120.95230294
57PBK0.93789427
58MAPKAPK30.91942615
59HCK0.90884765
60LCK0.89686290
61TRIB30.89512101
62GRK60.87779541
63MAP3K80.85522721
64MST40.85034992
65MATK0.84457531
66SIK30.81637870
67ACVR1B0.78457926
68DAPK10.77462274
69EIF2AK20.76809617
70STK160.76486494
71GRK70.74836660
72NEK20.72859208
73JAK10.71870611
74VRK10.71111092
75ABL20.70033139
76PKN20.69652297
77BMPR20.69193601
78CDC70.68495277
79MAPKAPK20.67989416
80MAP3K100.66934358
81PRKG20.66252950
82HIPK20.64621764
83TGFBR20.63808421
84MKNK10.62207295
85PTK60.61677374
86PAK10.61386795
87ILK0.60088448
88TGFBR10.60003011
89NEK10.59890114
90DAPK30.59313385
91PDK10.58682166
92PRKD20.58636080
93PDPK10.58414087
94MYLK0.58002333
95ITK0.57944118
96RPS6KA60.56954521
97MARK30.56263976
98BRAF0.56232634
99TAOK30.55728534
100MAP3K130.55575202
101MAPK110.54902602
102PRKCD0.54429816
103CAMKK20.54131611
104PTK2B0.54120413
105FLT30.53907846
106PRKCQ0.52280518
107CDC42BPA0.50099246
108RPS6KB20.49870487
109RPS6KL10.49825363
110RPS6KC10.49825363
111FGFR30.49656116
112TSSK60.49083847
113TAOK20.48350274
114CDK70.47844782
115PLK10.47674121
116SRPK10.46786992
117CDK40.45811961
118ERBB30.45658289
119ALK0.44324518
120MAP3K50.43338280
121PLK40.42415592
122MAPK120.41486988
123SIK10.41387135
124JAK20.40586303
125ZAK0.39961369
126FYN0.39799311
127AURKB0.39678369
128AURKA0.39347701
129MAP2K60.38943063
130YES10.38916306
131FGFR40.37593716
132FER0.36462849
133IRAK10.34489642
134BCKDK0.34444194
135ABL10.33364669
136MOS0.31802837
137CDK60.28503822
138PRKD10.28196831
139KSR20.26151763

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030502.84548427
2DNA replication_Homo sapiens_hsa030302.80622237
3Ribosome_Homo sapiens_hsa030102.55921568
4Leishmaniasis_Homo sapiens_hsa051402.42978368
5Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.22690807
6Primary immunodeficiency_Homo sapiens_hsa053401.93262846
7Mismatch repair_Homo sapiens_hsa034301.93031326
8Graft-versus-host disease_Homo sapiens_hsa053321.92791277
9Legionellosis_Homo sapiens_hsa051341.92641231
10Base excision repair_Homo sapiens_hsa034101.90006954
11Allograft rejection_Homo sapiens_hsa053301.89125325
12Antigen processing and presentation_Homo sapiens_hsa046121.87650039
13NF-kappa B signaling pathway_Homo sapiens_hsa040641.77166543
14Measles_Homo sapiens_hsa051621.74248212
15* Shigellosis_Homo sapiens_hsa051311.69279179
16Toll-like receptor signaling pathway_Homo sapiens_hsa046201.65088734
17Intestinal immune network for IgA production_Homo sapiens_hsa046721.63385864
18* Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.60476721
19Pertussis_Homo sapiens_hsa051331.58981260
20Osteoclast differentiation_Homo sapiens_hsa043801.58429925
21Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.52059944
22B cell receptor signaling pathway_Homo sapiens_hsa046621.51187734
23Herpes simplex infection_Homo sapiens_hsa051681.49321706
24Apoptosis_Homo sapiens_hsa042101.49269425
25Tuberculosis_Homo sapiens_hsa051521.45985247
26RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.45471695
27Homologous recombination_Homo sapiens_hsa034401.45420375
28Spliceosome_Homo sapiens_hsa030401.41215655
29Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.38306379
30Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.37901719
31NOD-like receptor signaling pathway_Homo sapiens_hsa046211.31167088
32RNA polymerase_Homo sapiens_hsa030201.31110720
33Epstein-Barr virus infection_Homo sapiens_hsa051691.29750516
34Asthma_Homo sapiens_hsa053101.28546279
35Other glycan degradation_Homo sapiens_hsa005111.28027999
36Influenza A_Homo sapiens_hsa051641.27505896
37* Salmonella infection_Homo sapiens_hsa051321.26126042
38p53 signaling pathway_Homo sapiens_hsa041151.25083420
39Malaria_Homo sapiens_hsa051441.23691309
40Hematopoietic cell lineage_Homo sapiens_hsa046401.21801232
41Nucleotide excision repair_Homo sapiens_hsa034201.21499347
42* Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.20995004
43Viral myocarditis_Homo sapiens_hsa054161.19877060
44Pyrimidine metabolism_Homo sapiens_hsa002401.17919600
45Cell cycle_Homo sapiens_hsa041101.17646758
46Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.17622884
47Hepatitis B_Homo sapiens_hsa051611.16762600
48Collecting duct acid secretion_Homo sapiens_hsa049661.16734767
49Toxoplasmosis_Homo sapiens_hsa051451.16144452
50Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.12011314
51Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.11323356
52Lysosome_Homo sapiens_hsa041421.10584775
53TNF signaling pathway_Homo sapiens_hsa046681.10434741
54Staphylococcus aureus infection_Homo sapiens_hsa051501.10378075
55Phagosome_Homo sapiens_hsa041451.10193744
56One carbon pool by folate_Homo sapiens_hsa006701.07831263
57* Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.07760567
58Vibrio cholerae infection_Homo sapiens_hsa051101.06751274
59Leukocyte transendothelial migration_Homo sapiens_hsa046701.06405764
60RNA transport_Homo sapiens_hsa030131.04798612
61Acute myeloid leukemia_Homo sapiens_hsa052211.02531966
62Chemokine signaling pathway_Homo sapiens_hsa040621.02230769
63Rheumatoid arthritis_Homo sapiens_hsa053230.99092229
64Jak-STAT signaling pathway_Homo sapiens_hsa046300.98664538
65T cell receptor signaling pathway_Homo sapiens_hsa046600.94213810
66Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.94067385
67Sulfur metabolism_Homo sapiens_hsa009200.93871545
68Autoimmune thyroid disease_Homo sapiens_hsa053200.92986241
69Viral carcinogenesis_Homo sapiens_hsa052030.92643928
70Type I diabetes mellitus_Homo sapiens_hsa049400.90100969
71Glycosaminoglycan degradation_Homo sapiens_hsa005310.86962393
72Chronic myeloid leukemia_Homo sapiens_hsa052200.84061635
73Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.83952187
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.81637998
75HTLV-I infection_Homo sapiens_hsa051660.80834142
76Galactose metabolism_Homo sapiens_hsa000520.80602306
77AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.78154567
78Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.77477517
79Pentose phosphate pathway_Homo sapiens_hsa000300.74694408
80Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.73528986
81Neurotrophin signaling pathway_Homo sapiens_hsa047220.73501782
82Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.71007457
83Pancreatic cancer_Homo sapiens_hsa052120.67772827
84Sphingolipid signaling pathway_Homo sapiens_hsa040710.66578685
85Platelet activation_Homo sapiens_hsa046110.63011741
86Hepatitis C_Homo sapiens_hsa051600.60575767
87Thyroid cancer_Homo sapiens_hsa052160.58771948
88Fructose and mannose metabolism_Homo sapiens_hsa000510.58313903
89Fanconi anemia pathway_Homo sapiens_hsa034600.57428009
90Non-homologous end-joining_Homo sapiens_hsa034500.55495431
91Small cell lung cancer_Homo sapiens_hsa052220.55295428
92Transcriptional misregulation in cancer_Homo sapiens_hsa052020.54303029
93HIF-1 signaling pathway_Homo sapiens_hsa040660.52997643
94Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.51119815
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.50499887
96RNA degradation_Homo sapiens_hsa030180.49896370
97African trypanosomiasis_Homo sapiens_hsa051430.49243576
98Bladder cancer_Homo sapiens_hsa052190.49137903
99Non-small cell lung cancer_Homo sapiens_hsa052230.46746458
100Systemic lupus erythematosus_Homo sapiens_hsa053220.45925094
101Colorectal cancer_Homo sapiens_hsa052100.45849364
102Sulfur relay system_Homo sapiens_hsa041220.44587112
103Prolactin signaling pathway_Homo sapiens_hsa049170.44563610
104SNARE interactions in vesicular transport_Homo sapiens_hsa041300.43279313
105VEGF signaling pathway_Homo sapiens_hsa043700.42997476
106Amoebiasis_Homo sapiens_hsa051460.42283803
107Glutathione metabolism_Homo sapiens_hsa004800.39475349
108Basal transcription factors_Homo sapiens_hsa030220.39347732
109Prion diseases_Homo sapiens_hsa050200.38476441
110* Regulation of actin cytoskeleton_Homo sapiens_hsa048100.38270152
111* Endocytosis_Homo sapiens_hsa041440.37884740
112Sphingolipid metabolism_Homo sapiens_hsa006000.37367555
113Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.36803824
114MicroRNAs in cancer_Homo sapiens_hsa052060.36589638
115Adipocytokine signaling pathway_Homo sapiens_hsa049200.26459722
116Renal cell carcinoma_Homo sapiens_hsa052110.25863912
117Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.23922761
118Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.19781118
119Synaptic vesicle cycle_Homo sapiens_hsa047210.19623443
120Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.19604571
121Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.19445539
122N-Glycan biosynthesis_Homo sapiens_hsa005100.16883634
123Phospholipase D signaling pathway_Homo sapiens_hsa040720.16090820
124Endometrial cancer_Homo sapiens_hsa052130.11293728

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