Rank | Gene Set | Z-score |
---|---|---|
1 | * Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.47437670 |
2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.40136590 |
3 | negative regulation of cell killing (GO:0031342) | 4.40136590 |
4 | neutrophil activation involved in immune response (GO:0002283) | 4.29595249 |
5 | negative regulation of interleukin-12 production (GO:0032695) | 3.93526121 |
6 | sequestering of actin monomers (GO:0042989) | 3.88559389 |
7 | ribosomal small subunit assembly (GO:0000028) | 3.87224195 |
8 | detection of other organism (GO:0098543) | 3.74549131 |
9 | immunoglobulin mediated immune response (GO:0016064) | 3.74301849 |
10 | detection of bacterium (GO:0016045) | 3.67956320 |
11 | respiratory burst (GO:0045730) | 3.66917002 |
12 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.57890043 |
13 | B cell mediated immunity (GO:0019724) | 3.51040685 |
14 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.45487755 |
15 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.45487755 |
16 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.39144231 |
17 | response to peptidoglycan (GO:0032494) | 3.34184809 |
18 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.31528424 |
19 | negative regulation of phagocytosis (GO:0050765) | 3.26050535 |
20 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.21321085 |
21 | * actin nucleation (GO:0045010) | 3.16968909 |
22 | leukocyte aggregation (GO:0070486) | 3.16790945 |
23 | amino sugar catabolic process (GO:0046348) | 3.13332567 |
24 | regulation of protein heterodimerization activity (GO:0043497) | 3.10067246 |
25 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.08689058 |
26 | neutrophil activation (GO:0042119) | 3.06869887 |
27 | positive regulation of interferon-alpha production (GO:0032727) | 3.05756975 |
28 | regulation of mast cell degranulation (GO:0043304) | 3.05423163 |
29 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.04466353 |
30 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.03759340 |
31 | detection of external biotic stimulus (GO:0098581) | 3.03023847 |
32 | viral transcription (GO:0019083) | 3.00887034 |
33 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.00066821 |
34 | modulation by symbiont of host immune response (GO:0052553) | 3.00066821 |
35 | positive regulation by symbiont of host defense response (GO:0052509) | 3.00066821 |
36 | modulation by symbiont of host defense response (GO:0052031) | 3.00066821 |
37 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.00066821 |
38 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.00066821 |
39 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.99693647 |
40 | regulation of gamma-delta T cell activation (GO:0046643) | 2.99542422 |
41 | regulation of T cell tolerance induction (GO:0002664) | 2.98196553 |
42 | positive thymic T cell selection (GO:0045059) | 2.97104488 |
43 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.97092660 |
44 | granulocyte activation (GO:0036230) | 2.95556440 |
45 | cellular response to zinc ion (GO:0071294) | 2.95353886 |
46 | regulation of interferon-alpha production (GO:0032647) | 2.91646881 |
47 | myeloid dendritic cell activation (GO:0001773) | 2.90535453 |
48 | translational termination (GO:0006415) | 2.88716278 |
49 | NIK/NF-kappaB signaling (GO:0038061) | 2.86292408 |
50 | hepatocyte apoptotic process (GO:0097284) | 2.86069292 |
51 | response to host immune response (GO:0052572) | 2.83605366 |
52 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.83605366 |
53 | natural killer cell mediated immunity (GO:0002228) | 2.81616213 |
54 | natural killer cell mediated cytotoxicity (GO:0042267) | 2.81616213 |
55 | positive regulation of antigen processing and presentation (GO:0002579) | 2.81599040 |
56 | T cell apoptotic process (GO:0070231) | 2.81440195 |
57 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.79280376 |
58 | regulation of leukocyte degranulation (GO:0043300) | 2.79066805 |
59 | DNA deamination (GO:0045006) | 2.78386838 |
60 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.78187870 |
61 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.76867886 |
62 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.76021800 |
63 | positive regulation of lamellipodium assembly (GO:0010592) | 2.75849427 |
64 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 2.74894272 |
65 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.74765891 |
66 | cellular response to interferon-beta (GO:0035458) | 2.73885261 |
67 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.73222255 |
68 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.71103788 |
69 | leukocyte degranulation (GO:0043299) | 2.69316442 |
70 | positive regulation of mast cell activation (GO:0033005) | 2.68788368 |
71 | formation of translation preinitiation complex (GO:0001731) | 2.68728970 |
72 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.68253484 |
73 | response to muramyl dipeptide (GO:0032495) | 2.68244958 |
74 | barbed-end actin filament capping (GO:0051016) | 2.67844454 |
75 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.67327813 |
76 | response to interferon-beta (GO:0035456) | 2.65733293 |
77 | myeloid dendritic cell differentiation (GO:0043011) | 2.64748143 |
78 | cellular extravasation (GO:0045123) | 2.64680997 |
79 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.64665629 |
80 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.64665629 |
81 | regulation of antigen processing and presentation (GO:0002577) | 2.64566754 |
82 | translational elongation (GO:0006414) | 2.64021110 |
83 | positive regulation of macrophage differentiation (GO:0045651) | 2.63977315 |
84 | DNA strand elongation (GO:0022616) | 2.63956692 |
85 | reactive oxygen species biosynthetic process (GO:1903409) | 2.63258322 |
86 | regulation of tolerance induction (GO:0002643) | 2.62835655 |
87 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.62734471 |
88 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.60713784 |
89 | hydrogen peroxide biosynthetic process (GO:0050665) | 2.60260685 |
90 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.59659577 |
91 | detection of biotic stimulus (GO:0009595) | 2.59519390 |
92 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.59500062 |
93 | lymphocyte chemotaxis (GO:0048247) | 2.59119689 |
94 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.58855578 |
95 | pinocytosis (GO:0006907) | 2.58845904 |
96 | regulation of mast cell activation (GO:0033003) | 2.58657496 |
97 | response to interleukin-15 (GO:0070672) | 2.58350249 |
98 | leukocyte mediated cytotoxicity (GO:0001909) | 2.58201176 |
99 | cellular response to interferon-gamma (GO:0071346) | 2.58168721 |
100 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.58045678 |
101 | regulation of lymphocyte migration (GO:2000401) | 2.57871623 |
102 | myeloid cell activation involved in immune response (GO:0002275) | 2.57081869 |
103 | response to host (GO:0075136) | 2.56692415 |
104 | response to host defenses (GO:0052200) | 2.56692415 |
105 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.56692415 |
106 | negative regulation of innate immune response (GO:0045824) | 2.55539360 |
107 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.55528133 |
108 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.55005255 |
109 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.54618033 |
110 | regulation of B cell differentiation (GO:0045577) | 2.54161554 |
111 | positive regulation of B cell differentiation (GO:0045579) | 2.53810992 |
112 | telomere maintenance via recombination (GO:0000722) | 2.53092883 |
113 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.52256856 |
114 | detection of molecule of bacterial origin (GO:0032490) | 2.52089655 |
115 | regulation of defense response to virus by virus (GO:0050690) | 2.51485202 |
116 | ribosomal large subunit biogenesis (GO:0042273) | 2.51348510 |
117 | macrophage activation (GO:0042116) | 2.50518111 |
118 | germinal center formation (GO:0002467) | 2.50126041 |
119 | phagosome maturation (GO:0090382) | 2.50033940 |
120 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.49993485 |
121 | protein targeting to ER (GO:0045047) | 2.49930831 |
122 | response to interferon-gamma (GO:0034341) | 2.49849462 |
123 | lymphocyte mediated immunity (GO:0002449) | 2.49380116 |
124 | cotranslational protein targeting to membrane (GO:0006613) | 2.49104780 |
125 | T cell migration (GO:0072678) | 2.46484473 |
126 | cellular response to type I interferon (GO:0071357) | 2.44778484 |
127 | type I interferon signaling pathway (GO:0060337) | 2.44778484 |
128 | mast cell activation (GO:0045576) | 2.44219913 |
129 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.44140820 |
130 | ribosomal small subunit biogenesis (GO:0042274) | 2.43001730 |
131 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.42779471 |
132 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.42758834 |
133 | translational initiation (GO:0006413) | 2.42520422 |
134 | B cell receptor signaling pathway (GO:0050853) | 2.41563398 |
135 | viral life cycle (GO:0019058) | 2.41518255 |
136 | lymphocyte apoptotic process (GO:0070227) | 2.41354433 |
137 | response to type I interferon (GO:0034340) | 2.41027068 |
138 | negative thymic T cell selection (GO:0045060) | 2.39944034 |
139 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 2.38611929 |
140 | superoxide anion generation (GO:0042554) | 2.37760133 |
141 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.37130344 |
142 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.36192519 |
143 | response to protozoan (GO:0001562) | 2.35901122 |
144 | protein localization to endoplasmic reticulum (GO:0070972) | 2.35796682 |
145 | defense response to protozoan (GO:0042832) | 2.35169054 |
146 | positive regulation of lamellipodium organization (GO:1902745) | 2.34775252 |
147 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.32425164 |
148 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.32035533 |
149 | macrophage activation involved in immune response (GO:0002281) | 2.31835204 |
150 | leukocyte cell-cell adhesion (GO:0007159) | 2.31090248 |
151 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.30646839 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.75405184 |
2 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.77320532 |
3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.46042647 |
4 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.27396551 |
5 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.05272698 |
6 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.78201165 |
7 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.62602904 |
8 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.53128093 |
9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.52477872 |
10 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.45356391 |
11 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.36820378 |
12 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.28972042 |
13 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.26224764 |
14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.21055626 |
15 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.11528052 |
16 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.10751256 |
17 | MYC_22102868_ChIP-Seq_BL_Human | 2.09419711 |
18 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.09299805 |
19 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.08491221 |
20 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.05849640 |
21 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.04707296 |
22 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.03492167 |
23 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.02961772 |
24 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.02956521 |
25 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.02766868 |
26 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.01534989 |
27 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.99669976 |
28 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.99471041 |
29 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.98054497 |
30 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.95058719 |
31 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.92234580 |
32 | * NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.91127840 |
33 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.90019020 |
34 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.84853780 |
35 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.84822117 |
36 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.83744336 |
37 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.79690276 |
38 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.79410938 |
39 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.75546450 |
40 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.74140532 |
41 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.69950716 |
42 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.68002084 |
43 | MAF_26560356_Chip-Seq_TH1_Human | 1.66525200 |
44 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.66508329 |
45 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.65100877 |
46 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.64734546 |
47 | MYB_26560356_Chip-Seq_TH2_Human | 1.64169795 |
48 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.63972143 |
49 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.63331989 |
50 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.62314076 |
51 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.60355254 |
52 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.58508490 |
53 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.58394844 |
54 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.55847980 |
55 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.53272205 |
56 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.53065599 |
57 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.52748140 |
58 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.49800914 |
59 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.49312775 |
60 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.47779344 |
61 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.47689208 |
62 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.44171068 |
63 | MYB_26560356_Chip-Seq_TH1_Human | 1.43169751 |
64 | UTX_26944678_Chip-Seq_JUKART_Human | 1.38665166 |
65 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.37587195 |
66 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.36299515 |
67 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.35174354 |
68 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.33208543 |
69 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.32322198 |
70 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31912705 |
71 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.31384997 |
72 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.30664889 |
73 | * ELK1_19687146_ChIP-ChIP_HELA_Human | 1.29947415 |
74 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.28045032 |
75 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.27111471 |
76 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.26527782 |
77 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.26518804 |
78 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.26353195 |
79 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.24251691 |
80 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.23746292 |
81 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.23407918 |
82 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.22106387 |
83 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.21026279 |
84 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.21017795 |
85 | MAF_26560356_Chip-Seq_TH2_Human | 1.20882876 |
86 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.20702430 |
87 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.20577416 |
88 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.19830191 |
89 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.19723193 |
90 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.19602952 |
91 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.19018097 |
92 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.18091881 |
93 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.17121768 |
94 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.16959989 |
95 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.16188942 |
96 | * BCOR_27268052_Chip-Seq_Bcells_Human | 1.15657314 |
97 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.14957862 |
98 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.13869967 |
99 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.13579961 |
100 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.12810622 |
101 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.12375501 |
102 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.11698229 |
103 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11304113 |
104 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.11262947 |
105 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.10033199 |
106 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.09003981 |
107 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.08952021 |
108 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.08703842 |
109 | SPI1_23127762_ChIP-Seq_K562_Human | 1.07527612 |
110 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.07182952 |
111 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.06081844 |
112 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.06046519 |
113 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.05770274 |
114 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.05624197 |
115 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.05170509 |
116 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.04939337 |
117 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.04880311 |
118 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.03808428 |
119 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.03488018 |
120 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.03353376 |
121 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.03021572 |
122 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.01939042 |
123 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.01647343 |
124 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.01510994 |
125 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.01396644 |
126 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.00484952 |
127 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.00413329 |
128 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.00395390 |
129 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.99706977 |
130 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.98955005 |
131 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.98745575 |
132 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.97626050 |
133 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.97622297 |
134 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.97581529 |
135 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.96711600 |
136 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.96406036 |
137 | * GATA3_26560356_Chip-Seq_TH2_Human | 0.94536028 |
138 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.91655509 |
139 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.90881999 |
140 | GATA1_19941826_ChIP-Seq_K562_Human | 0.89608961 |
141 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.88445109 |
142 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.87344931 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 4.20126627 |
2 | MP0003436_decreased_susceptibility_to | 3.41050575 |
3 | MP0003303_peritoneal_inflammation | 3.06740358 |
4 | MP0009785_altered_susceptibility_to | 3.03705425 |
5 | MP0002148_abnormal_hypersensitivity_rea | 3.03204061 |
6 | MP0000685_abnormal_immune_system | 2.80916859 |
7 | MP0005000_abnormal_immune_tolerance | 2.75082452 |
8 | MP0005671_abnormal_response_to | 2.72783099 |
9 | MP0002419_abnormal_innate_immunity | 2.59011784 |
10 | MP0002452_abnormal_antigen_presenting | 2.55254007 |
11 | MP0005025_abnormal_response_to | 2.55111138 |
12 | MP0001800_abnormal_humoral_immune | 2.50128014 |
13 | MP0001790_abnormal_immune_system | 2.40797017 |
14 | MP0005387_immune_system_phenotype | 2.40797017 |
15 | MP0001819_abnormal_immune_cell | 2.36864647 |
16 | MP0002420_abnormal_adaptive_immunity | 2.36621438 |
17 | MP0002723_abnormal_immune_serum | 2.31768982 |
18 | MP0009333_abnormal_splenocyte_physiolog | 2.31377856 |
19 | MP0006082_CNS_inflammation | 2.22570001 |
20 | MP0003724_increased_susceptibility_to | 2.21849147 |
21 | MP0003693_abnormal_embryo_hatching | 2.18871447 |
22 | MP0002398_abnormal_bone_marrow | 2.07373946 |
23 | MP0002405_respiratory_system_inflammati | 2.07087008 |
24 | MP0003763_abnormal_thymus_physiology | 2.05303232 |
25 | MP0002396_abnormal_hematopoietic_system | 1.94466445 |
26 | MP0000858_altered_metastatic_potential | 1.93779899 |
27 | MP0000716_abnormal_immune_system | 1.90271102 |
28 | MP0005464_abnormal_platelet_physiology | 1.88626074 |
29 | MP0001853_heart_inflammation | 1.80034141 |
30 | MP0001533_abnormal_skeleton_physiology | 1.78653632 |
31 | MP0000689_abnormal_spleen_morphology | 1.77772662 |
32 | MP0005058_abnormal_lysosome_morphology | 1.77414277 |
33 | MP0002166_altered_tumor_susceptibility | 1.74472907 |
34 | MP0002722_abnormal_immune_system | 1.72152666 |
35 | MP0008007_abnormal_cellular_replicative | 1.70906806 |
36 | MP0005397_hematopoietic_system_phenotyp | 1.70801198 |
37 | MP0001545_abnormal_hematopoietic_system | 1.70801198 |
38 | MP0003806_abnormal_nucleotide_metabolis | 1.70536944 |
39 | MP0002006_tumorigenesis | 1.69612299 |
40 | MP0002429_abnormal_blood_cell | 1.67863051 |
41 | MP0004808_abnormal_hematopoietic_stem | 1.67179925 |
42 | MP0000490_abnormal_crypts_of | 1.64263875 |
43 | MP0010155_abnormal_intestine_physiology | 1.62326254 |
44 | MP0001845_abnormal_inflammatory_respons | 1.61774197 |
45 | MP0003448_altered_tumor_morphology | 1.61313553 |
46 | MP0004957_abnormal_blastocyst_morpholog | 1.56264179 |
47 | MP0008260_abnormal_autophagy | 1.53767446 |
48 | MP0004510_myositis | 1.51726526 |
49 | MP0003077_abnormal_cell_cycle | 1.50030947 |
50 | MP0005451_abnormal_body_composition | 1.49921778 |
51 | MP0004947_skin_inflammation | 1.47067816 |
52 | MP0003111_abnormal_nucleus_morphology | 1.46057651 |
53 | MP0000343_altered_response_to | 1.42958623 |
54 | MP0010094_abnormal_chromosome_stability | 1.39000460 |
55 | MP0010307_abnormal_tumor_latency | 1.34430107 |
56 | MP0005310_abnormal_salivary_gland | 1.33329022 |
57 | MP0010352_gastrointestinal_tract_polyps | 1.33166744 |
58 | MP0000604_amyloidosis | 1.32141658 |
59 | MP0000703_abnormal_thymus_morphology | 1.30064851 |
60 | MP0009278_abnormal_bone_marrow | 1.23910193 |
61 | MP0003186_abnormal_redox_activity | 1.23878509 |
62 | MP0008469_abnormal_protein_level | 1.20935269 |
63 | MP0003566_abnormal_cell_adhesion | 1.20802001 |
64 | MP0010234_abnormal_vibrissa_follicle | 1.19221425 |
65 | MP0002019_abnormal_tumor_incidence | 1.17780351 |
66 | MP0006054_spinal_hemorrhage | 1.09698251 |
67 | MP0002933_joint_inflammation | 1.08589980 |
68 | MP0005076_abnormal_cell_differentiation | 1.07981280 |
69 | MP0005023_abnormal_wound_healing | 1.06121839 |
70 | MP0003172_abnormal_lysosome_physiology | 1.04954685 |
71 | MP0003866_abnormal_defecation | 1.04829713 |
72 | MP0000465_gastrointestinal_hemorrhage | 1.03898210 |
73 | MP0005174_abnormal_tail_pigmentation | 1.03648756 |
74 | MP0003300_gastrointestinal_ulcer | 1.02916720 |
75 | MP0005165_increased_susceptibility_to | 1.01066960 |
76 | MP0002254_reproductive_system_inflammat | 0.99406620 |
77 | MP0005075_abnormal_melanosome_morpholog | 0.98816398 |
78 | MP0001873_stomach_inflammation | 0.98464432 |
79 | MP0008438_abnormal_cutaneous_collagen | 0.97470230 |
80 | MP0005390_skeleton_phenotype | 0.95031625 |
81 | MP0009763_increased_sensitivity_to | 0.94229501 |
82 | MP0000313_abnormal_cell_death | 0.94009765 |
83 | MP0009840_abnormal_foam_cell | 0.93758725 |
84 | MP0002998_abnormal_bone_remodeling | 0.93220771 |
85 | MP0002877_abnormal_melanocyte_morpholog | 0.91071756 |
86 | MP0000350_abnormal_cell_proliferation | 0.90356401 |
87 | MP0002138_abnormal_hepatobiliary_system | 0.89884538 |
88 | MP0008932_abnormal_embryonic_tissue | 0.89804392 |
89 | MP0004883_abnormal_blood_vessel | 0.89267541 |
90 | MP0009764_decreased_sensitivity_to | 0.88519220 |
91 | MP0001542_abnormal_bone_strength | 0.88492944 |
92 | MP0004381_abnormal_hair_follicle | 0.87385829 |
93 | MP0003828_pulmonary_edema | 0.86339322 |
94 | MP0003795_abnormal_bone_structure | 0.85963230 |
95 | MP0002132_abnormal_respiratory_system | 0.83903206 |
96 | MP0003453_abnormal_keratinocyte_physiol | 0.82707155 |
97 | MP0008058_abnormal_DNA_repair | 0.82618893 |
98 | MP0008057_abnormal_DNA_replication | 0.82608669 |
99 | MP0003279_aneurysm | 0.81645563 |
100 | MP0001348_abnormal_lacrimal_gland | 0.81185729 |
101 | MP0000015_abnormal_ear_pigmentation | 0.79700738 |
102 | MP0005164_abnormal_response_to | 0.79578302 |
103 | MP0004782_abnormal_surfactant_physiolog | 0.79329361 |
104 | MP0002277_abnormal_respiratory_mucosa | 0.78652113 |
105 | MP0003075_altered_response_to | 0.78286238 |
106 | MP0008004_abnormal_stomach_pH | 0.77984955 |
107 | MP0002163_abnormal_gland_morphology | 0.76869492 |
108 | MP0001663_abnormal_digestive_system | 0.75514915 |
109 | MP0003786_premature_aging | 0.75050806 |
110 | MP0001851_eye_inflammation | 0.73056194 |
111 | MP0003183_abnormal_peptide_metabolism | 0.72650442 |
112 | MP0003045_fibrosis | 0.70946860 |
113 | MP0000249_abnormal_blood_vessel | 0.70260233 |
114 | MP0005166_decreased_susceptibility_to | 0.70175209 |
115 | MP0005167_abnormal_blood-brain_barrier | 0.69568253 |
116 | MP0003191_abnormal_cellular_cholesterol | 0.68363173 |
117 | MP0009379_abnormal_foot_pigmentation | 0.68129317 |
118 | MP0001915_intracranial_hemorrhage | 0.67842837 |
119 | MP0002139_abnormal_hepatobiliary_system | 0.67837929 |
120 | MP0001849_ear_inflammation | 0.66426316 |
121 | MP0003091_abnormal_cell_migration | 0.65894215 |
122 | MP0008874_decreased_physiological_sensi | 0.65864105 |
123 | MP0005319_abnormal_enzyme/_coenzyme | 0.64481844 |
124 | MP0002693_abnormal_pancreas_physiology | 0.63982929 |
125 | MP0003329_amyloid_beta_deposits | 0.63594284 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Recurrent abscess formation (HP:0002722) | 5.75681825 |
2 | Eczematoid dermatitis (HP:0000976) | 5.46425773 |
3 | Recurrent bacterial skin infections (HP:0005406) | 4.96288549 |
4 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.30893169 |
5 | Chronic obstructive pulmonary disease (HP:0006510) | 3.74801790 |
6 | Obstructive lung disease (HP:0006536) | 3.74801790 |
7 | Myositis (HP:0100614) | 3.73327588 |
8 | Mediastinal lymphadenopathy (HP:0100721) | 3.70155047 |
9 | Abnormality of macrophages (HP:0004311) | 3.69207088 |
10 | Autoimmune thrombocytopenia (HP:0001973) | 3.60499642 |
11 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.59131359 |
12 | Thrombocytosis (HP:0001894) | 3.53109655 |
13 | Recurrent fungal infections (HP:0002841) | 3.48553321 |
14 | Cellulitis (HP:0100658) | 3.41783621 |
15 | Vacuolated lymphocytes (HP:0001922) | 3.22630205 |
16 | Recurrent viral infections (HP:0004429) | 3.20377296 |
17 | Recurrent skin infections (HP:0001581) | 3.14869486 |
18 | Petechiae (HP:0000967) | 3.08032806 |
19 | Purpura (HP:0000979) | 3.06814776 |
20 | Meningitis (HP:0001287) | 3.01090678 |
21 | IgM deficiency (HP:0002850) | 2.95916552 |
22 | Chronic otitis media (HP:0000389) | 2.88409910 |
23 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.88267079 |
24 | Loss of speech (HP:0002371) | 2.87865077 |
25 | Poor head control (HP:0002421) | 2.83832763 |
26 | Abnormality of T cell physiology (HP:0011840) | 2.82481859 |
27 | Orchitis (HP:0100796) | 2.81462623 |
28 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.81089222 |
29 | Increased IgM level (HP:0003496) | 2.79200464 |
30 | Vasculitis (HP:0002633) | 2.73325446 |
31 | Prolonged bleeding time (HP:0003010) | 2.71858208 |
32 | Abnormality of the anterior horn cell (HP:0006802) | 2.71368494 |
33 | Degeneration of anterior horn cells (HP:0002398) | 2.71368494 |
34 | Agnosia (HP:0010524) | 2.68381411 |
35 | Vertebral compression fractures (HP:0002953) | 2.67728679 |
36 | Eosinophilia (HP:0001880) | 2.67715315 |
37 | Abnormality of T cells (HP:0002843) | 2.66455330 |
38 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.66198736 |
39 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.66198736 |
40 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.66198736 |
41 | Stomatitis (HP:0010280) | 2.66194520 |
42 | Pustule (HP:0200039) | 2.64868745 |
43 | Basal ganglia calcification (HP:0002135) | 2.63340139 |
44 | Gingivitis (HP:0000230) | 2.61788909 |
45 | Periodontitis (HP:0000704) | 2.61764420 |
46 | Leukocytosis (HP:0001974) | 2.59449858 |
47 | Increased IgE level (HP:0003212) | 2.58050694 |
48 | Urticaria (HP:0001025) | 2.56352071 |
49 | Recurrent cutaneous fungal infections (HP:0011370) | 2.55961329 |
50 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.55961329 |
51 | Granulocytopenia (HP:0001913) | 2.54576001 |
52 | Interstitial pulmonary disease (HP:0006530) | 2.54284646 |
53 | Increased cerebral lipofuscin (HP:0011813) | 2.53253130 |
54 | Gastrointestinal infarctions (HP:0005244) | 2.52942423 |
55 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.50792536 |
56 | Mucopolysacchariduria (HP:0008155) | 2.50792536 |
57 | Optic neuritis (HP:0100653) | 2.50553210 |
58 | Retrobulbar optic neuritis (HP:0100654) | 2.50553210 |
59 | Chest pain (HP:0100749) | 2.49449953 |
60 | Epistaxis (HP:0000421) | 2.49193481 |
61 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.48081778 |
62 | Hypergammaglobulinemia (HP:0010702) | 2.47983625 |
63 | Osteomyelitis (HP:0002754) | 2.46596215 |
64 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.46033056 |
65 | Abnormality of T cell number (HP:0011839) | 2.45747069 |
66 | Reticulocytopenia (HP:0001896) | 2.45706014 |
67 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.45698276 |
68 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.45698276 |
69 | Abnormality of glycolipid metabolism (HP:0010969) | 2.45698276 |
70 | Abnormal number of erythroid precursors (HP:0012131) | 2.43095619 |
71 | Agammaglobulinemia (HP:0004432) | 2.41830369 |
72 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.40419417 |
73 | Progressive neurologic deterioration (HP:0002344) | 2.40260849 |
74 | Increased serum ferritin (HP:0003281) | 2.39921345 |
75 | Recurrent bronchitis (HP:0002837) | 2.36304562 |
76 | Systemic lupus erythematosus (HP:0002725) | 2.32049069 |
77 | Recurrent lower respiratory tract infections (HP:0002783) | 2.25987188 |
78 | Lymphopenia (HP:0001888) | 2.25981982 |
79 | Recurrent pneumonia (HP:0006532) | 2.25507705 |
80 | Hematochezia (HP:0002573) | 2.24885894 |
81 | Gingival bleeding (HP:0000225) | 2.24849282 |
82 | Abnormality of eosinophils (HP:0001879) | 2.24127856 |
83 | Amyloidosis (HP:0011034) | 2.23957979 |
84 | Panhypogammaglobulinemia (HP:0003139) | 2.19263295 |
85 | Spontaneous hematomas (HP:0007420) | 2.16535111 |
86 | T lymphocytopenia (HP:0005403) | 2.11439549 |
87 | Episodic fever (HP:0001954) | 2.10345642 |
88 | Skin ulcer (HP:0200042) | 2.09453644 |
89 | Pulmonary fibrosis (HP:0002206) | 2.06326149 |
90 | Pulmonary infiltrates (HP:0002113) | 2.06274206 |
91 | Abnormality of iron homeostasis (HP:0011031) | 2.03344217 |
92 | Arterial thrombosis (HP:0004420) | 2.03206753 |
93 | IgG deficiency (HP:0004315) | 2.00606398 |
94 | Papilloma (HP:0012740) | 1.97829675 |
95 | Verrucae (HP:0200043) | 1.97829675 |
96 | Premature loss of primary teeth (HP:0006323) | 1.95915259 |
97 | Hypertensive crisis (HP:0100735) | 1.95735846 |
98 | Restrictive lung disease (HP:0002091) | 1.95372879 |
99 | Gastrointestinal inflammation (HP:0004386) | 1.94223330 |
100 | Abnormality of the prostate (HP:0008775) | 1.92948594 |
101 | Myocardial infarction (HP:0001658) | 1.92892964 |
102 | Keratoconjunctivitis sicca (HP:0001097) | 1.92871213 |
103 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.92661226 |
104 | Osteolytic defects of the hand bones (HP:0009699) | 1.92661226 |
105 | Lymphoma (HP:0002665) | 1.92600565 |
106 | Chronic diarrhea (HP:0002028) | 1.92101765 |
107 | Axonal loss (HP:0003447) | 1.90303998 |
108 | Anorexia (HP:0002039) | 1.89661837 |
109 | Inflammation of the large intestine (HP:0002037) | 1.89442366 |
110 | Dysostosis multiplex (HP:0000943) | 1.89233509 |
111 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.86971275 |
112 | Hepatosplenomegaly (HP:0001433) | 1.86799815 |
113 | Malnutrition (HP:0004395) | 1.85697421 |
114 | Nasal polyposis (HP:0100582) | 1.84977305 |
115 | Arthralgia (HP:0002829) | 1.84528272 |
116 | Pulmonary embolism (HP:0002204) | 1.83283365 |
117 | Encephalitis (HP:0002383) | 1.83174255 |
118 | Mutism (HP:0002300) | 1.82993837 |
119 | Hemoptysis (HP:0002105) | 1.82891598 |
120 | Sepsis (HP:0100806) | 1.82891034 |
121 | Pallor (HP:0000980) | 1.82131835 |
122 | IgA deficiency (HP:0002720) | 1.81822175 |
123 | Syringomyelia (HP:0003396) | 1.81701656 |
124 | Spinal cord lesions (HP:0100561) | 1.81701656 |
125 | Diminished motivation (HP:0000745) | 1.80913286 |
126 | Colitis (HP:0002583) | 1.80670060 |
127 | Disinhibition (HP:0000734) | 1.79629825 |
128 | Autoimmune hemolytic anemia (HP:0001890) | 1.79487686 |
129 | Abnormality of the nasal mucosa (HP:0000433) | 1.79008127 |
130 | Combined immunodeficiency (HP:0005387) | 1.77542440 |
131 | Gastrointestinal stroma tumor (HP:0100723) | 1.76522305 |
132 | Amaurosis fugax (HP:0100576) | 1.75847800 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BLK | 3.39045350 |
2 | PIM2 | 3.11703810 |
3 | MAP4K1 | 2.96288385 |
4 | TESK2 | 2.88120365 |
5 | MAP3K14 | 2.68732712 |
6 | NME2 | 2.66016782 |
7 | EIF2AK1 | 2.62847804 |
8 | IRAK4 | 2.51890481 |
9 | BUB1 | 2.27283572 |
10 | TBK1 | 2.25356251 |
11 | TESK1 | 2.16836643 |
12 | MAP3K3 | 2.09627263 |
13 | SMG1 | 1.94601117 |
14 | JAK3 | 1.92311890 |
15 | TLK1 | 1.91808938 |
16 | PRPF4B | 1.91749162 |
17 | IKBKE | 1.90797671 |
18 | ZAP70 | 1.81482739 |
19 | TYK2 | 1.80944567 |
20 | IKBKB | 1.80927396 |
21 | TXK | 1.74683923 |
22 | KIT | 1.69005076 |
23 | RIPK4 | 1.67940752 |
24 | STK10 | 1.67474427 |
25 | NEK9 | 1.66981604 |
26 | RPS6KA4 | 1.64745207 |
27 | PIM1 | 1.55363439 |
28 | VRK2 | 1.52955302 |
29 | IRAK3 | 1.47520035 |
30 | KDR | 1.47034985 |
31 | BTK | 1.44338677 |
32 | SCYL2 | 1.42763033 |
33 | LRRK2 | 1.41649106 |
34 | WEE1 | 1.41236397 |
35 | TAOK1 | 1.41220254 |
36 | MAP3K11 | 1.39534188 |
37 | SYK | 1.34900023 |
38 | TNK2 | 1.33146395 |
39 | FGR | 1.25856793 |
40 | ARAF | 1.24299335 |
41 | CSF1R | 1.23651645 |
42 | EPHB1 | 1.23014446 |
43 | TEC | 1.22415988 |
44 | LIMK1 | 1.20433767 |
45 | PAK4 | 1.15819908 |
46 | CLK1 | 1.15141018 |
47 | MAP2K3 | 1.13868025 |
48 | EIF2AK3 | 1.13055257 |
49 | CSK | 1.11856197 |
50 | ERN1 | 1.08668860 |
51 | MAP3K1 | 1.08126777 |
52 | STK4 | 1.07812758 |
53 | LYN | 1.00235561 |
54 | FES | 0.97777160 |
55 | CHUK | 0.95722419 |
56 | MAP3K12 | 0.95230294 |
57 | PBK | 0.93789427 |
58 | MAPKAPK3 | 0.91942615 |
59 | HCK | 0.90884765 |
60 | LCK | 0.89686290 |
61 | TRIB3 | 0.89512101 |
62 | GRK6 | 0.87779541 |
63 | MAP3K8 | 0.85522721 |
64 | MST4 | 0.85034992 |
65 | MATK | 0.84457531 |
66 | SIK3 | 0.81637870 |
67 | ACVR1B | 0.78457926 |
68 | DAPK1 | 0.77462274 |
69 | EIF2AK2 | 0.76809617 |
70 | STK16 | 0.76486494 |
71 | GRK7 | 0.74836660 |
72 | NEK2 | 0.72859208 |
73 | JAK1 | 0.71870611 |
74 | VRK1 | 0.71111092 |
75 | ABL2 | 0.70033139 |
76 | PKN2 | 0.69652297 |
77 | BMPR2 | 0.69193601 |
78 | CDC7 | 0.68495277 |
79 | MAPKAPK2 | 0.67989416 |
80 | MAP3K10 | 0.66934358 |
81 | PRKG2 | 0.66252950 |
82 | HIPK2 | 0.64621764 |
83 | TGFBR2 | 0.63808421 |
84 | MKNK1 | 0.62207295 |
85 | PTK6 | 0.61677374 |
86 | PAK1 | 0.61386795 |
87 | ILK | 0.60088448 |
88 | TGFBR1 | 0.60003011 |
89 | NEK1 | 0.59890114 |
90 | DAPK3 | 0.59313385 |
91 | PDK1 | 0.58682166 |
92 | PRKD2 | 0.58636080 |
93 | PDPK1 | 0.58414087 |
94 | MYLK | 0.58002333 |
95 | ITK | 0.57944118 |
96 | RPS6KA6 | 0.56954521 |
97 | MARK3 | 0.56263976 |
98 | BRAF | 0.56232634 |
99 | TAOK3 | 0.55728534 |
100 | MAP3K13 | 0.55575202 |
101 | MAPK11 | 0.54902602 |
102 | PRKCD | 0.54429816 |
103 | CAMKK2 | 0.54131611 |
104 | PTK2B | 0.54120413 |
105 | FLT3 | 0.53907846 |
106 | PRKCQ | 0.52280518 |
107 | CDC42BPA | 0.50099246 |
108 | RPS6KB2 | 0.49870487 |
109 | RPS6KC1 | 0.49825363 |
110 | RPS6KL1 | 0.49825363 |
111 | FGFR3 | 0.49656116 |
112 | TSSK6 | 0.49083847 |
113 | TAOK2 | 0.48350274 |
114 | CDK7 | 0.47844782 |
115 | PLK1 | 0.47674121 |
116 | SRPK1 | 0.46786992 |
117 | CDK4 | 0.45811961 |
118 | ERBB3 | 0.45658289 |
119 | ALK | 0.44324518 |
120 | MAP3K5 | 0.43338280 |
121 | PLK4 | 0.42415592 |
122 | MAPK12 | 0.41486988 |
123 | SIK1 | 0.41387135 |
124 | JAK2 | 0.40586303 |
125 | ZAK | 0.39961369 |
126 | FYN | 0.39799311 |
127 | AURKB | 0.39678369 |
128 | AURKA | 0.39347701 |
129 | MAP2K6 | 0.38943063 |
130 | YES1 | 0.38916306 |
131 | FGFR4 | 0.37593716 |
132 | FER | 0.36462849 |
133 | IRAK1 | 0.34489642 |
134 | BCKDK | 0.34444194 |
135 | ABL1 | 0.33364669 |
136 | MOS | 0.31802837 |
137 | CDK6 | 0.28503822 |
138 | PRKD1 | 0.28196831 |
139 | KSR2 | 0.26151763 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Proteasome_Homo sapiens_hsa03050 | 2.84548427 |
2 | DNA replication_Homo sapiens_hsa03030 | 2.80622237 |
3 | Ribosome_Homo sapiens_hsa03010 | 2.55921568 |
4 | Leishmaniasis_Homo sapiens_hsa05140 | 2.42978368 |
5 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.22690807 |
6 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.93262846 |
7 | Mismatch repair_Homo sapiens_hsa03430 | 1.93031326 |
8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.92791277 |
9 | Legionellosis_Homo sapiens_hsa05134 | 1.92641231 |
10 | Base excision repair_Homo sapiens_hsa03410 | 1.90006954 |
11 | Allograft rejection_Homo sapiens_hsa05330 | 1.89125325 |
12 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.87650039 |
13 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.77166543 |
14 | Measles_Homo sapiens_hsa05162 | 1.74248212 |
15 | * Shigellosis_Homo sapiens_hsa05131 | 1.69279179 |
16 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.65088734 |
17 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.63385864 |
18 | * Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.60476721 |
19 | Pertussis_Homo sapiens_hsa05133 | 1.58981260 |
20 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.58429925 |
21 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.52059944 |
22 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.51187734 |
23 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.49321706 |
24 | Apoptosis_Homo sapiens_hsa04210 | 1.49269425 |
25 | Tuberculosis_Homo sapiens_hsa05152 | 1.45985247 |
26 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.45471695 |
27 | Homologous recombination_Homo sapiens_hsa03440 | 1.45420375 |
28 | Spliceosome_Homo sapiens_hsa03040 | 1.41215655 |
29 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.38306379 |
30 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.37901719 |
31 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.31167088 |
32 | RNA polymerase_Homo sapiens_hsa03020 | 1.31110720 |
33 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.29750516 |
34 | Asthma_Homo sapiens_hsa05310 | 1.28546279 |
35 | Other glycan degradation_Homo sapiens_hsa00511 | 1.28027999 |
36 | Influenza A_Homo sapiens_hsa05164 | 1.27505896 |
37 | * Salmonella infection_Homo sapiens_hsa05132 | 1.26126042 |
38 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.25083420 |
39 | Malaria_Homo sapiens_hsa05144 | 1.23691309 |
40 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.21801232 |
41 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.21499347 |
42 | * Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.20995004 |
43 | Viral myocarditis_Homo sapiens_hsa05416 | 1.19877060 |
44 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.17919600 |
45 | Cell cycle_Homo sapiens_hsa04110 | 1.17646758 |
46 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.17622884 |
47 | Hepatitis B_Homo sapiens_hsa05161 | 1.16762600 |
48 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.16734767 |
49 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.16144452 |
50 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.12011314 |
51 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.11323356 |
52 | Lysosome_Homo sapiens_hsa04142 | 1.10584775 |
53 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.10434741 |
54 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.10378075 |
55 | Phagosome_Homo sapiens_hsa04145 | 1.10193744 |
56 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.07831263 |
57 | * Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.07760567 |
58 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.06751274 |
59 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.06405764 |
60 | RNA transport_Homo sapiens_hsa03013 | 1.04798612 |
61 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.02531966 |
62 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.02230769 |
63 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.99092229 |
64 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.98664538 |
65 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.94213810 |
66 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.94067385 |
67 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.93871545 |
68 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.92986241 |
69 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.92643928 |
70 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.90100969 |
71 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.86962393 |
72 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.84061635 |
73 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.83952187 |
74 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.81637998 |
75 | HTLV-I infection_Homo sapiens_hsa05166 | 0.80834142 |
76 | Galactose metabolism_Homo sapiens_hsa00052 | 0.80602306 |
77 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.78154567 |
78 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.77477517 |
79 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.74694408 |
80 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.73528986 |
81 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.73501782 |
82 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.71007457 |
83 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.67772827 |
84 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.66578685 |
85 | Platelet activation_Homo sapiens_hsa04611 | 0.63011741 |
86 | Hepatitis C_Homo sapiens_hsa05160 | 0.60575767 |
87 | Thyroid cancer_Homo sapiens_hsa05216 | 0.58771948 |
88 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.58313903 |
89 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.57428009 |
90 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.55495431 |
91 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.55295428 |
92 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.54303029 |
93 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.52997643 |
94 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.51119815 |
95 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.50499887 |
96 | RNA degradation_Homo sapiens_hsa03018 | 0.49896370 |
97 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.49243576 |
98 | Bladder cancer_Homo sapiens_hsa05219 | 0.49137903 |
99 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.46746458 |
100 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.45925094 |
101 | Colorectal cancer_Homo sapiens_hsa05210 | 0.45849364 |
102 | Sulfur relay system_Homo sapiens_hsa04122 | 0.44587112 |
103 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.44563610 |
104 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.43279313 |
105 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.42997476 |
106 | Amoebiasis_Homo sapiens_hsa05146 | 0.42283803 |
107 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.39475349 |
108 | Basal transcription factors_Homo sapiens_hsa03022 | 0.39347732 |
109 | Prion diseases_Homo sapiens_hsa05020 | 0.38476441 |
110 | * Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.38270152 |
111 | * Endocytosis_Homo sapiens_hsa04144 | 0.37884740 |
112 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.37367555 |
113 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.36803824 |
114 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.36589638 |
115 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.26459722 |
116 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.25863912 |
117 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.23922761 |
118 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.19781118 |
119 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.19623443 |
120 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.19604571 |
121 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.19445539 |
122 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.16883634 |
123 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.16090820 |
124 | Endometrial cancer_Homo sapiens_hsa05213 | 0.11293728 |