ARPC5L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proteasome assembly (GO:0043248)4.76364910
2DNA deamination (GO:0045006)4.50247614
3telomere maintenance via semi-conservative replication (GO:0032201)4.29414870
4chaperone-mediated protein transport (GO:0072321)4.18324890
5ribosomal small subunit assembly (GO:0000028)4.11533281
6establishment of protein localization to mitochondrial membrane (GO:0090151)3.97397677
7formation of translation preinitiation complex (GO:0001731)3.92621817
8DNA strand elongation involved in DNA replication (GO:0006271)3.91156653
9ribosomal large subunit biogenesis (GO:0042273)3.79259004
10telomere maintenance via recombination (GO:0000722)3.77473721
11viral transcription (GO:0019083)3.76533509
12DNA strand elongation (GO:0022616)3.72465770
13maturation of SSU-rRNA (GO:0030490)3.71774009
14regulation of translational termination (GO:0006449)3.70635060
15deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.64769814
16negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.63956073
17transcription elongation from RNA polymerase III promoter (GO:0006385)3.62875691
18termination of RNA polymerase III transcription (GO:0006386)3.62875691
19translational termination (GO:0006415)3.62104177
20SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.58116109
21regulation of mitochondrial translation (GO:0070129)3.56278212
22somatic diversification of immune receptors via somatic mutation (GO:0002566)3.54508076
23somatic hypermutation of immunoglobulin genes (GO:0016446)3.54508076
24ribosomal small subunit biogenesis (GO:0042274)3.54418562
25DNA replication checkpoint (GO:0000076)3.52778762
26protein deneddylation (GO:0000338)3.52126785
27pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.51630338
28mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.51597887
29protein targeting to mitochondrion (GO:0006626)3.51417092
30cotranslational protein targeting to membrane (GO:0006613)3.50942392
31protein targeting to ER (GO:0045047)3.47258525
32NIK/NF-kappaB signaling (GO:0038061)3.46674738
33regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.44421519
34ribosome assembly (GO:0042255)3.43670857
35cullin deneddylation (GO:0010388)3.42798616
36positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.41821513
37pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.41705652
38mitotic recombination (GO:0006312)3.40194310
39protein maturation by protein folding (GO:0022417)3.39820286
40mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.37821615
41telomere maintenance via telomere lengthening (GO:0010833)3.37382158
42anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.36039625
43cytidine deamination (GO:0009972)3.33500342
44cytidine metabolic process (GO:0046087)3.33500342
45cytidine catabolic process (GO:0006216)3.33500342
46translational elongation (GO:0006414)3.33208399
47DNA replication initiation (GO:0006270)3.33187166
48deoxyribonucleotide biosynthetic process (GO:0009263)3.31278572
49establishment of protein localization to mitochondrion (GO:0072655)3.30988135
50protein localization to endoplasmic reticulum (GO:0070972)3.30260269
51protein complex biogenesis (GO:0070271)3.29423628
52establishment of protein localization to endoplasmic reticulum (GO:0072599)3.29350478
53GDP-mannose metabolic process (GO:0019673)3.28971495
54CENP-A containing nucleosome assembly (GO:0034080)3.28819025
55rRNA modification (GO:0000154)3.28546038
56pseudouridine synthesis (GO:0001522)3.26974488
57negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.25611928
58negative regulation of ligase activity (GO:0051352)3.25611928
59translation (GO:0006412)3.25550499
60transcription-coupled nucleotide-excision repair (GO:0006283)3.25300965
612-deoxyribonucleotide biosynthetic process (GO:0009265)3.24783677
62deoxyribose phosphate biosynthetic process (GO:0046385)3.24783677
63chromatin remodeling at centromere (GO:0031055)3.23851326
64ribonucleoprotein complex biogenesis (GO:0022613)3.22909691
65nucleotide-excision repair, DNA gap filling (GO:0006297)3.22591714
66iron-sulfur cluster assembly (GO:0016226)3.21435725
67metallo-sulfur cluster assembly (GO:0031163)3.21435725
68activation of MAPKKK activity (GO:0000185)3.19636634
69energy coupled proton transport, down electrochemical gradient (GO:0015985)3.19300604
70ATP synthesis coupled proton transport (GO:0015986)3.19300604
71translational initiation (GO:0006413)3.18696723
72nucleobase-containing small molecule interconversion (GO:0015949)3.15367448
73spliceosomal snRNP assembly (GO:0000387)3.14881819
74protein localization to mitochondrion (GO:0070585)3.14356109
757-methylguanosine mRNA capping (GO:0006370)3.14030641
76regulation of cellular amino acid metabolic process (GO:0006521)3.13864766
77DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.12694288
78mitochondrial respiratory chain complex assembly (GO:0033108)3.11826480
79regulation of ubiquitin-protein transferase activity (GO:0051438)3.11199489
80L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.09958288
81signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.09605622
82signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.09605622
83signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.09605622
84negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.08952161
85intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.08818083
86signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.08818083
87positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.07797764
88RNA capping (GO:0036260)3.06145055
897-methylguanosine RNA capping (GO:0009452)3.06145055
90pyrimidine nucleotide catabolic process (GO:0006244)3.04723753
91mitochondrial respiratory chain complex I assembly (GO:0032981)3.03721138
92NADH dehydrogenase complex assembly (GO:0010257)3.03721138
93mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.03721138
94regulation of ligase activity (GO:0051340)3.03406823
95nuclear envelope reassembly (GO:0031468)3.03204898
96mitotic nuclear envelope reassembly (GO:0007084)3.03204898
97establishment of viral latency (GO:0019043)3.02390175
98antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.02268399
99signal transduction involved in cell cycle checkpoint (GO:0072395)3.00723410
100cellular protein complex disassembly (GO:0043624)3.00094398
101respiratory electron transport chain (GO:0022904)2.99694320
102exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.98750594
103cellular component biogenesis (GO:0044085)2.98555799
104signal transduction involved in DNA integrity checkpoint (GO:0072401)2.97943781
105signal transduction involved in DNA damage checkpoint (GO:0072422)2.97943781
106deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.97719958
107rRNA processing (GO:0006364)2.97093017
108antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.96303333
109ribosome biogenesis (GO:0042254)2.95975626
110maturation of 5.8S rRNA (GO:0000460)2.95792828
111positive regulation of ligase activity (GO:0051351)2.95220869
112electron transport chain (GO:0022900)2.94680362
113spliceosomal complex assembly (GO:0000245)2.94297545
114rRNA methylation (GO:0031167)2.93979240
115nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.92627947
116viral life cycle (GO:0019058)2.92430297
117mitotic metaphase plate congression (GO:0007080)2.90195949
118DNA replication-independent nucleosome assembly (GO:0006336)2.90154893
119DNA replication-independent nucleosome organization (GO:0034724)2.90154893
120nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.90094579
121regulation of double-strand break repair via homologous recombination (GO:0010569)2.89924409
122rRNA transcription (GO:0009303)2.89586162
123positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.88479815
124peptidyl-histidine modification (GO:0018202)2.88148522
125transcription from mitochondrial promoter (GO:0006390)2.86348969
126rRNA metabolic process (GO:0016072)2.85653353
127mitotic chromosome condensation (GO:0007076)2.83891193
128establishment of integrated proviral latency (GO:0075713)2.83633137
129positive regulation of cell cycle arrest (GO:0071158)2.79212980
130peptidyl-arginine omega-N-methylation (GO:0035247)2.78958094
131chaperone mediated protein folding requiring cofactor (GO:0051085)2.75719421
132regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.75226931
133DNA unwinding involved in DNA replication (GO:0006268)2.71892172

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.57567159
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.43259794
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.03757245
4* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.88752238
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.76570640
6MYC_18555785_ChIP-Seq_MESCs_Mouse3.64010286
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.33732299
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.32798226
9HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.15488315
10EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.11711997
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.00717344
12VDR_23849224_ChIP-Seq_CD4+_Human2.81246577
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.77311820
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.69752772
15* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.69154468
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.63394882
17* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.50684050
18FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.47992650
19FOXP3_21729870_ChIP-Seq_TREG_Human2.42064741
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.38097748
21DCP1A_22483619_ChIP-Seq_HELA_Human2.33492345
22THAP11_20581084_ChIP-Seq_MESCs_Mouse2.26769611
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.26738148
24SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.26177118
25* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.22441038
26E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.18610633
27FOXM1_23109430_ChIP-Seq_U2OS_Human2.14918940
28* GABP_19822575_ChIP-Seq_HepG2_Human2.14776021
29XRN2_22483619_ChIP-Seq_HELA_Human2.14409858
30* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.14266279
31FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.10163294
32SRF_21415370_ChIP-Seq_HL-1_Mouse2.08671518
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.08605478
34MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.04903518
35CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.04219178
36FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.02369408
37YY1_21170310_ChIP-Seq_MESCs_Mouse2.00665188
38PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.99598367
39* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.94527677
40E2F1_18555785_ChIP-Seq_MESCs_Mouse1.93251630
41TTF2_22483619_ChIP-Seq_HELA_Human1.91883443
42CIITA_25753668_ChIP-Seq_RAJI_Human1.91514815
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.87272283
44BP1_19119308_ChIP-ChIP_Hs578T_Human1.85005455
45ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.83219828
46ELK1_19687146_ChIP-ChIP_HELA_Human1.83081848
47SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.82190453
48ZNF263_19887448_ChIP-Seq_K562_Human1.81700894
49TP63_17297297_ChIP-ChIP_HaCaT_Human1.73359349
50IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.71232324
51YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.63572207
52* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.62174273
53* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.61208915
54* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.56093851
55* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.48419032
56* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.46729097
57ERG_20887958_ChIP-Seq_HPC-7_Mouse1.45385381
58PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.43776664
59E2F1_21310950_ChIP-Seq_MCF-7_Human1.43548746
60CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.42775399
61SRY_22984422_ChIP-ChIP_TESTIS_Rat1.41978604
62NOTCH1_21737748_ChIP-Seq_TLL_Human1.40207531
63KDM5A_27292631_Chip-Seq_BREAST_Human1.38005538
64POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.37374969
65* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.36863405
66MYC_18940864_ChIP-ChIP_HL60_Human1.35656165
67* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.31126897
68FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.30255225
69BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.28507662
70MAF_26560356_Chip-Seq_TH2_Human1.28434939
71* ELK3_25401928_ChIP-Seq_HUVEC_Human1.26974369
72GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.24032320
73HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.22573077
74LXR_22292898_ChIP-Seq_THP-1_Human1.22325746
75PADI4_21655091_ChIP-ChIP_MCF-7_Human1.21770473
76NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.21105554
77TET1_21451524_ChIP-Seq_MESCs_Mouse1.20403926
78SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.19103349
79* MAF_26560356_Chip-Seq_TH1_Human1.18780845
80TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15940576
81STAT3_1855785_ChIP-Seq_MESCs_Mouse1.15809631
82* MYC_22102868_ChIP-Seq_BL_Human1.15536801
83NANOG_18555785_ChIP-Seq_MESCs_Mouse1.12630718
84SPI1_23547873_ChIP-Seq_NB4_Human1.12108272
85E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08024365
86ELK1_22589737_ChIP-Seq_MCF10A_Human1.07803166
87ELF1_20517297_ChIP-Seq_JURKAT_Human1.07743784
88RBPJ_22232070_ChIP-Seq_NCS_Mouse1.05819228
89KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.05711161
90CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.05550680
91RACK7_27058665_Chip-Seq_MCF-7_Human1.03918607
92ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03537102
93IRF8_22096565_ChIP-ChIP_GC-B_Human1.02272733
94* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01825711
95* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.01701587
96UTX_26944678_Chip-Seq_JUKART_Human1.01605272
97ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.01436185
98AR_21909140_ChIP-Seq_LNCAP_Human1.01026966
99SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.00831791
100* ATF3_27146783_Chip-Seq_COLON_Human1.00017258
101CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.99924514
102ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.99119494
103P68_20966046_ChIP-Seq_HELA_Human0.98200134
104KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.97621107
105DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.97202392
106* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.96974686
107CTCF_18555785_ChIP-Seq_MESCs_Mouse0.95976203
108TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.95974143
109IRF1_19129219_ChIP-ChIP_H3396_Human0.95167437
110* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95088656
111FOXP1_21924763_ChIP-Seq_HESCs_Human0.93831534
112ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.93756780
113EZH2_22144423_ChIP-Seq_EOC_Human0.88147220
114POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.86867519
115* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.81641601
116CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.79579607
117FLI1_27457419_Chip-Seq_LIVER_Mouse0.79562469
118PU.1_20513432_ChIP-Seq_Bcells_Mouse0.79520871
119CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.79225176
120EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.79140276
121TFEB_21752829_ChIP-Seq_HELA_Human0.77186948
122* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.76696414
123VDR_21846776_ChIP-Seq_THP-1_Human0.75499358
124STAT4_19710469_ChIP-ChIP_TH1__Mouse0.73939682
125CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.73402395
126* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.73079041
127CTCF_26484167_Chip-Seq_Bcells_Mouse0.71356041
128YY1_22570637_ChIP-Seq_MALME-3M_Human0.70366905

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.30887653
2MP0010094_abnormal_chromosome_stability3.63128520
3MP0004957_abnormal_blastocyst_morpholog3.10843893
4MP0003646_muscle_fatigue3.02897049
5MP0003111_abnormal_nucleus_morphology3.00226905
6MP0008877_abnormal_DNA_methylation2.91252771
7MP0008058_abnormal_DNA_repair2.88116183
8MP0003806_abnormal_nucleotide_metabolis2.75536703
9MP0003077_abnormal_cell_cycle2.70707342
10MP0002796_impaired_skin_barrier2.60789682
11MP0002877_abnormal_melanocyte_morpholog2.56740392
12MP0001986_abnormal_taste_sensitivity2.52595735
13MP0003763_abnormal_thymus_physiology2.52275679
14MP0005451_abnormal_body_composition2.45300600
15MP0005501_abnormal_skin_physiology2.44564772
16MP0001835_abnormal_antigen_presentation2.42799473
17MP0008260_abnormal_autophagy2.26182013
18MP0001800_abnormal_humoral_immune2.11088493
19MP0008007_abnormal_cellular_replicative2.05574272
20MP0006036_abnormal_mitochondrial_physio1.99735336
21MP0003718_maternal_effect1.99104977
22MP0006292_abnormal_olfactory_placode1.97886176
23MP0008057_abnormal_DNA_replication1.97067464
24MP0008932_abnormal_embryonic_tissue1.96638539
25MP0009379_abnormal_foot_pigmentation1.95736597
26MP0005623_abnormal_meninges_morphology1.90885188
27MP0003786_premature_aging1.89658061
28MP0001529_abnormal_vocalization1.87918403
29MP0010234_abnormal_vibrissa_follicle1.86935698
30MP0005671_abnormal_response_to1.86252112
31MP0001188_hyperpigmentation1.82404505
32MP0001790_abnormal_immune_system1.81515743
33MP0005387_immune_system_phenotype1.81515743
34MP0002398_abnormal_bone_marrow1.78724330
35MP0000015_abnormal_ear_pigmentation1.66795046
36MP0003787_abnormal_imprinting1.64432333
37MP0009333_abnormal_splenocyte_physiolog1.62855332
38MP0001984_abnormal_olfaction1.61748327
39MP0004185_abnormal_adipocyte_glucose1.60512277
40MP0003453_abnormal_keratinocyte_physiol1.58525330
41MP0000689_abnormal_spleen_morphology1.57526817
42MP0002420_abnormal_adaptive_immunity1.57204658
43MP0002452_abnormal_antigen_presenting1.56596364
44MP0002163_abnormal_gland_morphology1.56590427
45MP0001905_abnormal_dopamine_level1.55905523
46MP0002160_abnormal_reproductive_system1.54433729
47MP0001819_abnormal_immune_cell1.52959602
48MP0001873_stomach_inflammation1.45606563
49MP0003880_abnormal_central_pattern1.44138595
50MP0000716_abnormal_immune_system1.43636417
51MP0004233_abnormal_muscle_weight1.43332450
52MP0004947_skin_inflammation1.43262776
53MP0000703_abnormal_thymus_morphology1.42875631
54MP0002723_abnormal_immune_serum1.42523226
55MP0000858_altered_metastatic_potential1.38024007
56MP0005000_abnormal_immune_tolerance1.37920950
57MP0003186_abnormal_redox_activity1.37703541
58MP0006035_abnormal_mitochondrial_morpho1.37235447
59MP0002095_abnormal_skin_pigmentation1.35776153
60MP0001727_abnormal_embryo_implantation1.35357634
61MP0002722_abnormal_immune_system1.35239262
62MP0001929_abnormal_gametogenesis1.34855255
63MP0005645_abnormal_hypothalamus_physiol1.34631598
64MP0001216_abnormal_epidermal_layer1.30538748
65MP0002429_abnormal_blood_cell1.27283644
66MP0005389_reproductive_system_phenotype1.27033909
67MP0002210_abnormal_sex_determination1.24678577
68MP0002736_abnormal_nociception_after1.21735871
69MP0002019_abnormal_tumor_incidence1.20899476
70MP0003436_decreased_susceptibility_to1.19791402
71MP0001968_abnormal_touch/_nociception1.18150014
72MP0001919_abnormal_reproductive_system1.16936608
73MP0003941_abnormal_skin_development1.16925008
74MP0004145_abnormal_muscle_electrophysio1.16308535
75MP0002148_abnormal_hypersensitivity_rea1.16207530
76MP0009840_abnormal_foam_cell1.15942700
77MP0002396_abnormal_hematopoietic_system1.14273363
78MP0000490_abnormal_crypts_of1.12727989
79MP0000685_abnormal_immune_system1.11114420
80MP0000313_abnormal_cell_death1.09583948
81MP0010307_abnormal_tumor_latency1.09209112
82MP0001881_abnormal_mammary_gland1.09157450
83MP0001853_heart_inflammation1.06082594
84MP0002080_prenatal_lethality1.04164517
85MP0003123_paternal_imprinting1.04039648
86MP0002837_dystrophic_cardiac_calcinosis1.03883764
87MP0006276_abnormal_autonomic_nervous1.03458385
88MP0010771_integument_phenotype1.03354917
89MP0000372_irregular_coat_pigmentation1.03089521
90MP0002132_abnormal_respiratory_system1.02163990
91MP0005410_abnormal_fertilization1.01874022
92MP0002006_tumorigenesis1.01776972
93MP0002693_abnormal_pancreas_physiology1.00405762
94MP0002138_abnormal_hepatobiliary_system0.99401783
95MP0004808_abnormal_hematopoietic_stem0.99157874
96MP0005646_abnormal_pituitary_gland0.98612367
97MP0003183_abnormal_peptide_metabolism0.97740069
98MP0000653_abnormal_sex_gland0.97366195
99MP0001145_abnormal_male_reproductive0.96284870
100MP0000750_abnormal_muscle_regeneration0.96191911
101MP0009785_altered_susceptibility_to0.95541215
102MP0001348_abnormal_lacrimal_gland0.95118932
103MP0005075_abnormal_melanosome_morpholog0.94924670
104MP0002060_abnormal_skin_morphology0.94907015
105MP0002166_altered_tumor_susceptibility0.94507120
106MP0003698_abnormal_male_reproductive0.94260871
107MP0000579_abnormal_nail_morphology0.93997040
108MP0000350_abnormal_cell_proliferation0.91981917
109MP0005621_abnormal_cell_physiology0.88261178
110MP0001730_embryonic_growth_arrest0.88092910
111MP0003866_abnormal_defecation0.87041459
112MP0002876_abnormal_thyroid_physiology0.86327963
113MP0000627_abnormal_mammary_gland0.86169069
114MP0005384_cellular_phenotype0.85481512
115MP0004142_abnormal_muscle_tone0.84372143
116MP0005379_endocrine/exocrine_gland_phen0.83640720
117MP0001845_abnormal_inflammatory_respons0.82889276
118MP0002751_abnormal_autonomic_nervous0.81851032
119MP0000013_abnormal_adipose_tissue0.81835041
120MP0003121_genomic_imprinting0.81447590
121MP0000749_muscle_degeneration0.81376343
122MP0001119_abnormal_female_reproductive0.81374499
123MP0010155_abnormal_intestine_physiology0.80387894
124MP0001697_abnormal_embryo_size0.78136039
125MP0005310_abnormal_salivary_gland0.77444161
126MP0005025_abnormal_response_to0.77057816
127MP0002638_abnormal_pupillary_reflex0.76774871
128MP0005330_cardiomyopathy0.76353582
129MP0005174_abnormal_tail_pigmentation0.76026445
130MP0010386_abnormal_urinary_bladder0.75623437
131MP0005058_abnormal_lysosome_morphology0.75241341
132MP0009931_abnormal_skin_appearance0.74806281
133MP0001191_abnormal_skin_condition0.74765224
134MP0000358_abnormal_cell_content/0.74695204
135MP0003448_altered_tumor_morphology0.72549853
136MP0008873_increased_physiological_sensi0.71250267
137MP0000343_altered_response_to0.71128351
138MP0003075_altered_response_to0.71054167
139MP0006072_abnormal_retinal_apoptosis0.70334158
140MP0003221_abnormal_cardiomyocyte_apopto0.69311159
141MP0003315_abnormal_perineum_morphology0.69189535
142MP0009672_abnormal_birth_weight0.69041611
143MP0008789_abnormal_olfactory_epithelium0.67116041
144MP0001672_abnormal_embryogenesis/_devel0.66673141
145MP0000751_myopathy0.66516181
146MP0000631_abnormal_neuroendocrine_gland0.65594042
147MP0002405_respiratory_system_inflammati0.63619520
148MP0001186_pigmentation_phenotype0.62958032

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.51917347
2Abnormal mitochondria in muscle tissue (HP:0008316)4.28860487
3Agammaglobulinemia (HP:0004432)4.24901602
4Mitochondrial inheritance (HP:0001427)4.20908998
5Hepatocellular necrosis (HP:0001404)3.92320581
6Increased CSF lactate (HP:0002490)3.84887616
7Progressive macrocephaly (HP:0004481)3.68948058
8Decreased activity of mitochondrial respiratory chain (HP:0008972)3.60556747
9Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.60556747
10Acute encephalopathy (HP:0006846)3.44355200
11Hepatic necrosis (HP:0002605)3.28937534
12Increased hepatocellular lipid droplets (HP:0006565)3.19751426
13Testicular atrophy (HP:0000029)3.18119758
14Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.12804395
15Ragged-red muscle fibers (HP:0003200)3.08795157
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.08486847
17Abnormality of cells of the erythroid lineage (HP:0012130)3.07423985
18Multiple enchondromatosis (HP:0005701)3.07325117
19Gastrointestinal stroma tumor (HP:0100723)3.06671785
20Trismus (HP:0000211)3.03724399
21Sparse eyelashes (HP:0000653)3.01358863
22Rough bone trabeculation (HP:0100670)3.00075669
23Recurrent sinusitis (HP:0011108)3.00074007
24Abnormal number of erythroid precursors (HP:0012131)2.99361847
25Recurrent bronchitis (HP:0002837)2.98899620
26Reticulocytopenia (HP:0001896)2.94355261
27Birth length less than 3rd percentile (HP:0003561)2.91307838
28IgM deficiency (HP:0002850)2.88784378
29Increased serum lactate (HP:0002151)2.88645545
30Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.87299639
31Exercise intolerance (HP:0003546)2.83232575
32Exertional dyspnea (HP:0002875)2.81131190
33Aplastic anemia (HP:0001915)2.80814467
34Lipid accumulation in hepatocytes (HP:0006561)2.79335317
35Chronic sinusitis (HP:0011109)2.77559054
36Congenital ichthyosiform erythroderma (HP:0007431)2.76554558
37Lactic acidosis (HP:0003128)2.71432141
38Increased intramyocellular lipid droplets (HP:0012240)2.64848352
39Squamous cell carcinoma (HP:0002860)2.59403826
40IgG deficiency (HP:0004315)2.52459726
41Panhypogammaglobulinemia (HP:0003139)2.52152549
42Abnormal hair whorl (HP:0010721)2.51438898
43Lymphopenia (HP:0001888)2.41625759
44Selective tooth agenesis (HP:0001592)2.41014063
45Respiratory difficulties (HP:0002880)2.40907628
46Amniotic constriction ring (HP:0009775)2.39436285
47Abnormality of placental membranes (HP:0011409)2.39436285
48Type I transferrin isoform profile (HP:0003642)2.38925724
49Macrocytic anemia (HP:0001972)2.37938087
50Hypertensive crisis (HP:0100735)2.37528034
51Abnormality of cells of the lymphoid lineage (HP:0012140)2.36852948
52Respiratory failure (HP:0002878)2.35946894
53Verrucae (HP:0200043)2.35911639
54Papilloma (HP:0012740)2.35911639
55B lymphocytopenia (HP:0010976)2.34652031
56Abnormality of B cell number (HP:0010975)2.34652031
57Bronchitis (HP:0012387)2.33655257
58Abnormal trabecular bone morphology (HP:0100671)2.33371807
59Hypoplasia of the capital femoral epiphysis (HP:0003090)2.32883473
60Abnormality of nail color (HP:0100643)2.32845410
61Microvesicular hepatic steatosis (HP:0001414)2.32714619
62Hypokinesia (HP:0002375)2.32623412
63Onycholysis (HP:0001806)2.31233598
64IgA deficiency (HP:0002720)2.29659827
65Fatigue (HP:0012378)2.28387835
66Chromosomal breakage induced by crosslinking agents (HP:0003221)2.28009684
67Chromsome breakage (HP:0040012)2.25641605
68Meningitis (HP:0001287)2.25471606
69Optic disc pallor (HP:0000543)2.22865889
70Fasciculations (HP:0002380)2.21861810
71Renal Fanconi syndrome (HP:0001994)2.21423636
72Recurrent viral infections (HP:0004429)2.21267397
73Medial flaring of the eyebrow (HP:0010747)2.19951238
74Fragile nails (HP:0001808)2.19236015
75Increased muscle lipid content (HP:0009058)2.18144397
76Breast hypoplasia (HP:0003187)2.17458846
77Patellar aplasia (HP:0006443)2.17288753
78Premature ovarian failure (HP:0008209)2.17281252
79Abnormality of the preputium (HP:0100587)2.13428045
80Recurrent pneumonia (HP:0006532)2.11251665
81Abnormal delayed hypersensitivity skin test (HP:0002963)2.10209828
82Cerebral hypomyelination (HP:0006808)2.09339461
83Abnormality of alanine metabolism (HP:0010916)2.09079948
84Hyperalaninemia (HP:0003348)2.09079948
85Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.09079948
86Aplasia/Hypoplasia of the patella (HP:0006498)2.06886229
87Absent thumb (HP:0009777)2.06807618
88Achilles tendon contracture (HP:0001771)2.06657145
89Pallor (HP:0000980)2.06156789
90Aplasia/Hypoplasia of the sacrum (HP:0008517)2.05814800
91Entropion (HP:0000621)2.04501215
92Dysphonia (HP:0001618)2.04451617
93Unsteady gait (HP:0002317)2.03529470
94Lymphoma (HP:0002665)2.03453630
95Hypoplasia of the pons (HP:0012110)2.02387554
96Cerebral edema (HP:0002181)2.01813938
973-Methylglutaconic aciduria (HP:0003535)2.01787418
98Carpal bone hypoplasia (HP:0001498)2.01650432
99Pulmonary fibrosis (HP:0002206)2.00804085
100Progressive external ophthalmoplegia (HP:0000590)1.99352033
101Hypothermia (HP:0002045)1.98584858
102Pancreatic cysts (HP:0001737)1.97176533
103Severe combined immunodeficiency (HP:0004430)1.96832620
104Oral leukoplakia (HP:0002745)1.96584726
105Nail dystrophy (HP:0008404)1.94934575
106Recurrent lower respiratory tract infections (HP:0002783)1.94711906
107Muscle stiffness (HP:0003552)1.94587680
108Thyroiditis (HP:0100646)1.93938029
109Pancreatic fibrosis (HP:0100732)1.93245574
110Overlapping toe (HP:0001845)1.93073396
111Microretrognathia (HP:0000308)1.92403911
112Meckel diverticulum (HP:0002245)1.91453620
113Pancytopenia (HP:0001876)1.88531965
114Leukodystrophy (HP:0002415)1.88095157
115Cellulitis (HP:0100658)1.87762519
116Seborrheic dermatitis (HP:0001051)1.85435254
117Emotional lability (HP:0000712)1.83693432
118Secondary amenorrhea (HP:0000869)1.82910759
119Abnormal protein glycosylation (HP:0012346)1.82595297
120Abnormal glycosylation (HP:0012345)1.82595297
121Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.82595297
122Abnormal protein N-linked glycosylation (HP:0012347)1.82595297
123Progressive muscle weakness (HP:0003323)1.82028620
124Recurrent otitis media (HP:0000403)1.81529671
125Type 2 muscle fiber atrophy (HP:0003554)1.81459256
126Abnormality of the pons (HP:0007361)1.81395142
127Increased serum pyruvate (HP:0003542)1.80527739
12811 pairs of ribs (HP:0000878)1.80275031
129Abnormality of the ileum (HP:0001549)1.80089210
130Deep palmar crease (HP:0006191)1.79754646
131Muscle fiber atrophy (HP:0100295)1.79732080
132Nephrogenic diabetes insipidus (HP:0009806)1.79575697
133Abnormality of T cells (HP:0002843)1.79433702
134Rhabdomyolysis (HP:0003201)1.78751356
135Focal motor seizures (HP:0011153)1.78320616
136Aplasia/Hypoplasia of the thymus (HP:0010515)1.77664761
137Gout (HP:0001997)1.77663575
138Abnormal lung lobation (HP:0002101)1.77282245
139True hermaphroditism (HP:0010459)1.77043849
140Abnormality of T cell physiology (HP:0011840)1.76538204
141Reduced antithrombin III activity (HP:0001976)1.74945820
142Sensory axonal neuropathy (HP:0003390)1.73588656
143Centrally nucleated skeletal muscle fibers (HP:0003687)1.72646541
144Death in infancy (HP:0001522)1.72051596
145Abnormality of glycolysis (HP:0004366)1.71362016
146Upper limb muscle weakness (HP:0003484)1.71228778
147Myopathic facies (HP:0002058)1.70790474
148Poikiloderma (HP:0001029)1.68689008

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.34444811
2EIF2AK14.27830369
3TLK12.79900948
4STK162.79050317
5EIF2AK32.78289230
6VRK22.69906876
7MAP4K12.57304262
8PLK42.55943238
9SRPK12.55229978
10NME22.54284510
11VRK12.19943554
12TAOK22.12266541
13WEE12.04414112
14CASK1.98318134
15SMG11.98295441
16BRAF1.90231006
17ARAF1.88528651
18NME11.87087337
19CDC71.81749649
20TESK21.75805470
21ERN11.72405360
22PRPF4B1.71595499
23CCNB11.71176696
24PBK1.67412936
25EPHA21.57685189
26ACVR1B1.47961958
27SYK1.47400465
28MUSK1.44073493
29MAP3K121.38283379
30IRAK31.35528189
31STK101.32944505
32MAP3K91.31580341
33LIMK11.27589898
34NEK11.21397222
35MST41.20548745
36CDK191.20440894
37IRAK41.16798926
38PLK11.15154006
39MAP3K81.14979673
40DYRK31.13374934
41ZAP701.11598016
42PAK41.10711579
43BLK1.09413041
44BMPR21.09062319
45GRK61.08951172
46AURKA1.08518555
47BRSK11.07743697
48MAP2K71.06980923
49LATS21.06774057
50TEC1.05102145
51PINK11.04911828
52BRSK21.02123457
53PRKCI1.00751707
54TRIB31.00513299
55TSSK60.99523591
56ALK0.99057327
57MAPKAPK30.98891002
58TBK10.96641183
59MAPK130.96155269
60NEK20.88635619
61MAP3K30.88158600
62STK38L0.87923190
63MKNK20.87119068
64ZAK0.85287129
65AURKB0.83668942
66CHEK20.82474390
67MAP3K140.82063768
68YES10.81701768
69ILK0.81667167
70ABL20.81261951
71TTK0.81066496
72CDK70.80515200
73PLK30.79862589
74SCYL20.79620268
75SIK10.79019076
76DYRK20.76858597
77BTK0.76831733
78TESK10.76066810
79CLK10.75751801
80ATR0.75657533
81NLK0.75052743
82MOS0.74549308
83TXK0.73921558
84MAP3K130.72339857
85LRRK20.71564382
86MAP3K100.70955518
87SIK30.70600425
88TNK20.70224314
89DAPK30.67977263
90TAOK10.67534650
91LYN0.67322055
92MKNK10.66986504
93MAP3K110.62079443
94PASK0.61659310
95PIM20.61532879
96RPS6KA40.60711453
97PIK3CG0.60358686
98MST1R0.58732640
99PAK10.58678077
100CSNK2A10.57742597
101MAP3K50.57260041
102DAPK10.57157211
103BCKDK0.54838656
104MAPK110.52381539
105RAF10.52291666
106CSNK2A20.50374537
107IRAK20.50087736
108KDR0.48787462
109RIPK40.48777315
110DMPK0.48463291
111STK240.48210139
112CDK11A0.47916152
113IKBKE0.45684322
114STK40.45078254
115PDK30.43537185
116PDK40.43537185
117RPS6KA50.42025389
118RPS6KB20.41841640
119EIF2AK20.40825251
120MAP3K10.40704554
121PIM10.40266451
122MAP2K30.40165785
123CHEK10.39452852
124CDK120.38367624
125PLK20.36180362
126CDK80.35726589
127CDK140.35605018
128IRAK10.35214326
129AKT20.34725970
130MARK30.34708266
131PRKCQ0.34494841
132PDK20.33094934
133PRKCH0.32917338
134CDK40.31692819
135CDK150.31626569
136TAF10.31562962
137CSNK1G30.31530780
138ADRBK20.30184584
139IKBKB0.27137678
140CSNK1G10.26227967
141OBSCN0.25539010
142CSF1R0.24578960
143LCK0.23791883
144HIPK20.23081470
145PRKCG0.22733604

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.02024505
2Ribosome_Homo sapiens_hsa030104.01364808
3Proteasome_Homo sapiens_hsa030503.92543457
4Mismatch repair_Homo sapiens_hsa034303.69037498
5RNA polymerase_Homo sapiens_hsa030203.21801275
6Homologous recombination_Homo sapiens_hsa034403.13704219
7Oxidative phosphorylation_Homo sapiens_hsa001903.03094360
8Base excision repair_Homo sapiens_hsa034102.91214049
9Parkinsons disease_Homo sapiens_hsa050122.85375498
10Primary immunodeficiency_Homo sapiens_hsa053402.62672238
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.61488386
12Protein export_Homo sapiens_hsa030602.56153071
13Spliceosome_Homo sapiens_hsa030402.55151089
14Pyrimidine metabolism_Homo sapiens_hsa002402.42019099
15Nucleotide excision repair_Homo sapiens_hsa034202.41999807
16Fanconi anemia pathway_Homo sapiens_hsa034602.23349365
17Huntingtons disease_Homo sapiens_hsa050162.19189839
18Alzheimers disease_Homo sapiens_hsa050101.93998969
19Basal transcription factors_Homo sapiens_hsa030221.90611644
20RNA transport_Homo sapiens_hsa030131.88495408
21Non-homologous end-joining_Homo sapiens_hsa034501.75713497
22Cell cycle_Homo sapiens_hsa041101.68418824
23Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.61766294
24RNA degradation_Homo sapiens_hsa030181.54210284
25Purine metabolism_Homo sapiens_hsa002301.51492610
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.40492252
27Biosynthesis of amino acids_Homo sapiens_hsa012301.12218831
28Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.11492187
29Epstein-Barr virus infection_Homo sapiens_hsa051691.11383368
30B cell receptor signaling pathway_Homo sapiens_hsa046621.06343652
31Viral myocarditis_Homo sapiens_hsa054161.05981427
32mRNA surveillance pathway_Homo sapiens_hsa030151.04855785
33SNARE interactions in vesicular transport_Homo sapiens_hsa041300.99995928
34Intestinal immune network for IgA production_Homo sapiens_hsa046720.99837336
35Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.96434200
36One carbon pool by folate_Homo sapiens_hsa006700.95778641
37Cardiac muscle contraction_Homo sapiens_hsa042600.94794919
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.94295908
39Oocyte meiosis_Homo sapiens_hsa041140.88768063
402-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.87057979
41p53 signaling pathway_Homo sapiens_hsa041150.86758441
42Antigen processing and presentation_Homo sapiens_hsa046120.84955179
43Bladder cancer_Homo sapiens_hsa052190.82225474
44Carbon metabolism_Homo sapiens_hsa012000.77045773
45Prion diseases_Homo sapiens_hsa050200.72729541
46Toll-like receptor signaling pathway_Homo sapiens_hsa046200.72593245
47Fructose and mannose metabolism_Homo sapiens_hsa000510.71928755
48Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.71418076
49Sulfur metabolism_Homo sapiens_hsa009200.68926049
50Vibrio cholerae infection_Homo sapiens_hsa051100.68509206
51Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.68222529
52Herpes simplex infection_Homo sapiens_hsa051680.67604197
53Rheumatoid arthritis_Homo sapiens_hsa053230.67005058
54Fatty acid elongation_Homo sapiens_hsa000620.60195693
55Collecting duct acid secretion_Homo sapiens_hsa049660.59898912
56Hematopoietic cell lineage_Homo sapiens_hsa046400.59017570
57Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.58540769
58N-Glycan biosynthesis_Homo sapiens_hsa005100.58170624
59Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.56649433
60Regulation of autophagy_Homo sapiens_hsa041400.55006883
61NF-kappa B signaling pathway_Homo sapiens_hsa040640.53474544
62Folate biosynthesis_Homo sapiens_hsa007900.53403887
63Systemic lupus erythematosus_Homo sapiens_hsa053220.52696228
64Olfactory transduction_Homo sapiens_hsa047400.51172876
65Alcoholism_Homo sapiens_hsa050340.50201201
66Other glycan degradation_Homo sapiens_hsa005110.49714398
67Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.48002277
68Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.47579243
69* Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.47040391
70Measles_Homo sapiens_hsa051620.46454638
71Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.46043335
72Galactose metabolism_Homo sapiens_hsa000520.43822948
73Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.42098166
74Metabolic pathways_Homo sapiens_hsa011000.41965657
75* Salmonella infection_Homo sapiens_hsa051320.41261324
76T cell receptor signaling pathway_Homo sapiens_hsa046600.39979053
77Glutathione metabolism_Homo sapiens_hsa004800.39132529
78Type I diabetes mellitus_Homo sapiens_hsa049400.38459924
79Viral carcinogenesis_Homo sapiens_hsa052030.35880245
80* Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.35371701
81HTLV-I infection_Homo sapiens_hsa051660.34719625
82Acute myeloid leukemia_Homo sapiens_hsa052210.34232470
83Synaptic vesicle cycle_Homo sapiens_hsa047210.33302753
84Sulfur relay system_Homo sapiens_hsa041220.33017842
85Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.32161567
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.32084699
87Toxoplasmosis_Homo sapiens_hsa051450.31744012
88Thyroid cancer_Homo sapiens_hsa052160.31245934
89TNF signaling pathway_Homo sapiens_hsa046680.31074107
90Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.30139072
91Cyanoamino acid metabolism_Homo sapiens_hsa004600.29723881
92Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.29720811
93Pentose phosphate pathway_Homo sapiens_hsa000300.29591186
94RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.29266839
95Graft-versus-host disease_Homo sapiens_hsa053320.29063662
96Amphetamine addiction_Homo sapiens_hsa050310.27600123
97VEGF signaling pathway_Homo sapiens_hsa043700.26610769
98Central carbon metabolism in cancer_Homo sapiens_hsa052300.26272909
99Chronic myeloid leukemia_Homo sapiens_hsa052200.25439828
100Pancreatic cancer_Homo sapiens_hsa052120.25281074
101Cysteine and methionine metabolism_Homo sapiens_hsa002700.23821972
102Long-term potentiation_Homo sapiens_hsa047200.23605624
103Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.22085038
104* Shigellosis_Homo sapiens_hsa051310.21819058
105Allograft rejection_Homo sapiens_hsa053300.19385215
106Phototransduction_Homo sapiens_hsa047440.18928926
107Sphingolipid metabolism_Homo sapiens_hsa006000.18046535
108Taste transduction_Homo sapiens_hsa047420.17996961
109Influenza A_Homo sapiens_hsa051640.17933618
110Nicotine addiction_Homo sapiens_hsa050330.15507072
111Pyruvate metabolism_Homo sapiens_hsa006200.13644226
112Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.13375187
113Dopaminergic synapse_Homo sapiens_hsa047280.12592357
114Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.12463068
115Arachidonic acid metabolism_Homo sapiens_hsa005900.11749238
116Hepatitis B_Homo sapiens_hsa051610.11406972
117Maturity onset diabetes of the young_Homo sapiens_hsa049500.11308707
118Autoimmune thyroid disease_Homo sapiens_hsa053200.10958950
119Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.10327127
120Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.09726217
121Vitamin B6 metabolism_Homo sapiens_hsa007500.08980333
122Serotonergic synapse_Homo sapiens_hsa047260.08113067
123Asthma_Homo sapiens_hsa053100.07985679
124Apoptosis_Homo sapiens_hsa042100.07232514
125* Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.05852755
126Linoleic acid metabolism_Homo sapiens_hsa005910.05213868
127Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.05109266
128FoxO signaling pathway_Homo sapiens_hsa040680.04970910

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