ART1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1actin-myosin filament sliding (GO:0033275)9.36625676
2muscle filament sliding (GO:0030049)9.36625676
3sarcomere organization (GO:0045214)8.86553416
4regulation of skeletal muscle contraction (GO:0014819)8.45481248
5actin-mediated cell contraction (GO:0070252)7.68265499
6myofibril assembly (GO:0030239)7.52242898
7sarcoplasmic reticulum calcium ion transport (GO:0070296)7.49243514
8positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)7.31832696
9cardiac myofibril assembly (GO:0055003)7.18504169
10plasma membrane repair (GO:0001778)7.16656657
11negative regulation of potassium ion transmembrane transporter activity (GO:1901017)7.13498977
12skeletal muscle contraction (GO:0003009)6.65790797
13regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)6.57209454
14negative regulation of potassium ion transmembrane transport (GO:1901380)6.24856123
15myotube cell development (GO:0014904)6.18046720
16cardiac muscle contraction (GO:0060048)6.15450116
17striated muscle contraction (GO:0006941)6.12740420
18tricarboxylic acid cycle (GO:0006099)6.11183794
19regulation of relaxation of muscle (GO:1901077)5.91950260
20regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.74690505
21carnitine shuttle (GO:0006853)5.74523383
22actin filament-based movement (GO:0030048)5.72519304
23regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.68416073
24response to stimulus involved in regulation of muscle adaptation (GO:0014874)5.67974607
25actomyosin structure organization (GO:0031032)5.65688474
26regulation of cell communication by electrical coupling (GO:0010649)5.62855587
27skeletal muscle adaptation (GO:0043501)5.57201332
28regulation of actin filament-based movement (GO:1903115)5.51104186
29cardiac muscle cell development (GO:0055013)5.47865900
30regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO5.34813884
31creatine metabolic process (GO:0006600)5.31333433
32regulation of acyl-CoA biosynthetic process (GO:0050812)5.23139608
33regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)5.19029173
34cardiac cell development (GO:0055006)5.13250270
35skeletal muscle tissue development (GO:0007519)4.99718378
36fatty acid transmembrane transport (GO:1902001)4.90876431
37heart contraction (GO:0060047)4.77769069
38heart process (GO:0003015)4.77769069
39skeletal muscle tissue regeneration (GO:0043403)4.75108057
40regulation of coenzyme metabolic process (GO:0051196)4.74653901
41regulation of cofactor metabolic process (GO:0051193)4.74653901
42regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)4.70153242
43cardiac muscle tissue morphogenesis (GO:0055008)4.67098250
44regulation of striated muscle contraction (GO:0006942)4.63340431
45adult heart development (GO:0007512)4.61496088
46cardiac muscle hypertrophy (GO:0003300)4.59618281
47regulation of sarcomere organization (GO:0060297)4.59058128
48ventricular cardiac muscle cell action potential (GO:0086005)4.57199566
49response to inactivity (GO:0014854)4.53060051
50muscle contraction (GO:0006936)4.50094433
51striated muscle hypertrophy (GO:0014897)4.49159551
52muscle tissue morphogenesis (GO:0060415)4.36262840
53mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.30763951
54fructose metabolic process (GO:0006000)4.30160162
55heart trabecula formation (GO:0060347)4.29581109
56carnitine transmembrane transport (GO:1902603)4.26441980
57mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.23778653
58striated muscle adaptation (GO:0014888)4.23093765
59regulation of membrane repolarization (GO:0060306)4.23017523
60muscle organ morphogenesis (GO:0048644)4.21941897
61bundle of His cell to Purkinje myocyte communication (GO:0086069)4.19959786
62pyrimidine ribonucleoside catabolic process (GO:0046133)4.14067854
63striated muscle atrophy (GO:0014891)4.13663957
64glycogen catabolic process (GO:0005980)4.13292434
65muscle system process (GO:0003012)4.11931963
66response to activity (GO:0014823)4.10389770
67response to muscle activity (GO:0014850)4.09194909
68glycogen metabolic process (GO:0005977)4.08948603
69muscle cell cellular homeostasis (GO:0046716)4.08319834
70positive regulation of myotube differentiation (GO:0010831)4.06223507
71respiratory electron transport chain (GO:0022904)4.06082772
72cellular glucan metabolic process (GO:0006073)4.02005236
73glucan metabolic process (GO:0044042)4.02005236
74ventricular cardiac muscle tissue morphogenesis (GO:0055010)4.00466665
75muscle hypertrophy (GO:0014896)3.95822961
76positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.94786179
77cytidine metabolic process (GO:0046087)3.93890726
78cytidine catabolic process (GO:0006216)3.93890726
79cytidine deamination (GO:0009972)3.93890726
80electron transport chain (GO:0022900)3.93746483
81oxidative phosphorylation (GO:0006119)3.93597009
82energy coupled proton transport, down electrochemical gradient (GO:0015985)3.93535974
83ATP synthesis coupled proton transport (GO:0015986)3.93535974
84NADH metabolic process (GO:0006734)3.93357350
852-oxoglutarate metabolic process (GO:0006103)3.91228596
86regulation of sequestering of triglyceride (GO:0010889)3.90594256
87amino-acid betaine transport (GO:0015838)3.88549964
88carnitine transport (GO:0015879)3.88549964
89muscle structure development (GO:0061061)3.87102269
90regulation of sulfur metabolic process (GO:0042762)3.85909009
91glucan catabolic process (GO:0009251)3.85714718
92muscle organ development (GO:0007517)3.85203291
93striated muscle cell development (GO:0055002)3.84569576
94gluconeogenesis (GO:0006094)3.81596171
95muscle cell fate commitment (GO:0042693)3.80936490
96neuronal action potential propagation (GO:0019227)3.71123987
97positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.69594488
98muscle fiber development (GO:0048747)3.66891465
99regulation of calcium ion transmembrane transport (GO:1903169)3.66504917
100regulation of calcium ion transmembrane transporter activity (GO:1901019)3.66504917
101IMP metabolic process (GO:0046040)3.64089233
102cellular polysaccharide catabolic process (GO:0044247)3.58668225
103myoblast fusion (GO:0007520)3.57835600
104cardiac muscle hypertrophy in response to stress (GO:0014898)3.57289343
105muscle hypertrophy in response to stress (GO:0003299)3.57289343
106cardiac muscle adaptation (GO:0014887)3.57289343
107glucan biosynthetic process (GO:0009250)3.54871802
108glycogen biosynthetic process (GO:0005978)3.54871802
109muscle atrophy (GO:0014889)3.52802935
110regulation of ATPase activity (GO:0043462)3.52379655
111regulation of ATP catabolic process (GO:1903289)3.52379655
112muscle adaptation (GO:0043500)3.52337019
113negative regulation of muscle contraction (GO:0045932)3.51775622
114regulation of the force of heart contraction (GO:0002026)3.51518490
115neuromuscular synaptic transmission (GO:0007274)3.51471720
116positive regulation of cation channel activity (GO:2001259)3.51263053
117regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.48120644
118ubiquinone biosynthetic process (GO:0006744)3.47741804
119negative regulation of calcium ion transmembrane transport (GO:1903170)3.45260426
120negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.45260426
121negative regulation of necroptotic process (GO:0060546)3.45228278
122negative regulation of protein localization to cell surface (GO:2000009)3.44780393
123negative regulation of potassium ion transport (GO:0043267)3.44188664
124cellular carbohydrate catabolic process (GO:0044275)3.42464049
125hexose biosynthetic process (GO:0019319)3.41488607
126regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.41225111
127polysaccharide catabolic process (GO:0000272)3.39456079
128skeletal muscle fiber development (GO:0048741)3.38480067
129cell communication involved in cardiac conduction (GO:0086065)3.38404780
130striated muscle tissue development (GO:0014706)3.34144337
131muscle cell development (GO:0055001)3.31914331
132regulation of skeletal muscle cell differentiation (GO:2001014)3.31194443
133regulation of myoblast differentiation (GO:0045661)3.30002821
134leukotriene biosynthetic process (GO:0019370)3.19930717
135relaxation of muscle (GO:0090075)3.16992593
136regulation of muscle system process (GO:0090257)3.16525150
137positive regulation of myoblast differentiation (GO:0045663)3.15676386

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse6.70762585
2ESRRB_18555785_ChIP-Seq_MESCs_Mouse4.54653191
3BP1_19119308_ChIP-ChIP_Hs578T_Human4.46633917
4TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse4.33395502
5TBX20_22328084_ChIP-Seq_HEART_Mouse3.89487613
6TBX20_22080862_ChIP-Seq_HEART_Mouse3.89487613
7EP300_21415370_ChIP-Seq_HL-1_Mouse3.86920140
8ESR1_20079471_ChIP-ChIP_T-47D_Human3.42187631
9ZNF263_19887448_ChIP-Seq_K562_Human3.25435021
10RARG_19884340_ChIP-ChIP_MEFs_Mouse2.88290979
11RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.80740704
12MEF2A_21415370_ChIP-Seq_HL-1_Mouse2.79652765
13CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.54877804
14PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.30413550
15THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.24410905
16GATA4_21415370_ChIP-Seq_HL-1_Mouse2.19356407
17CDX2_19796622_ChIP-Seq_MESCs_Mouse2.06131652
18ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.96548028
19GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.91770903
20EZH2_22144423_ChIP-Seq_EOC_Human1.90953547
21AR_21572438_ChIP-Seq_LNCaP_Human1.88566090
22BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.84442092
23NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.75706010
24ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.73191539
25NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.70485157
26EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.68709809
27ESR2_21235772_ChIP-Seq_MCF-7_Human1.63305358
28TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.59425084
29CLOCK_20551151_ChIP-Seq_293T_Human1.59274534
30PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.52082974
31CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.50602300
32TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.49408730
33EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.48756365
34* CTCF_27219007_Chip-Seq_Bcells_Human1.43714377
35PPARA_22158963_ChIP-Seq_LIVER_Mouse1.43157446
36NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.36879275
37BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.36087989
38IGF1R_20145208_ChIP-Seq_DFB_Human1.31753635
39RBPJ_22232070_ChIP-Seq_NCS_Mouse1.28935294
40PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.28212642
41NFIB_24661679_ChIP-Seq_LUNG_Mouse1.26965098
42SUZ12_27294783_Chip-Seq_NPCs_Mouse1.26093837
43KDM2B_26808549_Chip-Seq_DND41_Human1.25605616
44ZNF274_21170338_ChIP-Seq_K562_Hela1.24943121
45KDM2B_26808549_Chip-Seq_SUP-B15_Human1.24835999
46SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.24305832
47CTCF_21964334_ChIP-Seq_BJAB-B_Human1.23813688
48PCGF2_27294783_Chip-Seq_ESCs_Mouse1.23343487
49FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.19675131
50FLI1_27457419_Chip-Seq_LIVER_Mouse1.18745058
51SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.18701674
52LXR_22158963_ChIP-Seq_LIVER_Mouse1.17921318
53TP63_22573176_ChIP-Seq_HFKS_Human1.14821253
54EZH2_27294783_Chip-Seq_ESCs_Mouse1.14759517
55RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.14583580
56LXR_22292898_ChIP-Seq_THP-1_Human1.14334994
57P68_20966046_ChIP-Seq_HELA_Human1.13489251
58CRX_20693478_ChIP-Seq_RETINA_Mouse1.13416153
59RARB_27405468_Chip-Seq_BRAIN_Mouse1.13169415
60DROSHA_22980978_ChIP-Seq_HELA_Human1.12792987
61SMC3_22415368_ChIP-Seq_MEFs_Mouse1.12067813
62P53_22127205_ChIP-Seq_FIBROBLAST_Human1.11394794
63OCT4_20526341_ChIP-Seq_ESCs_Human1.10642745
64FOXH1_21741376_ChIP-Seq_ESCs_Human1.09442838
65EZH2_27294783_Chip-Seq_NPCs_Mouse1.08484857
66SPI1_20517297_ChIP-Seq_HL60_Human1.07552581
67CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.07249885
68RACK7_27058665_Chip-Seq_MCF-7_Human1.06044331
69YY1_22570637_ChIP-Seq_MALME-3M_Human1.05296033
70RXR_22158963_ChIP-Seq_LIVER_Mouse1.05033748
71ESR1_21235772_ChIP-Seq_MCF-7_Human1.04514139
72CTCF_21964334_Chip-Seq_Bcells_Human1.03648599
73ATF3_27146783_Chip-Seq_COLON_Human1.03635983
74TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03463732
75STAT1_20625510_ChIP-Seq_HELA_Human1.03127975
76EGR1_19032775_ChIP-ChIP_M12_Human1.00889186
77PPAR_26484153_Chip-Seq_NCI-H1993_Human1.00701170
78OCT4_21477851_ChIP-Seq_ESCs_Mouse1.00552965
79GBX2_23144817_ChIP-Seq_PC3_Human0.99868945
80GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.99272316
81EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.98534095
82HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.98020022
83CBX2_27304074_Chip-Seq_ESCs_Mouse0.97884131
84STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.97734845
85SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.96799665
86TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96467216
87* STAT3_1855785_ChIP-Seq_MESCs_Mouse0.96462529
88BCL6_27268052_Chip-Seq_Bcells_Human0.95937801
89ER_23166858_ChIP-Seq_MCF-7_Human0.95640725
90GATA1_22025678_ChIP-Seq_K562_Human0.95498009
91SMC1_22415368_ChIP-Seq_MEFs_Mouse0.94755231
92ELK3_25401928_ChIP-Seq_HUVEC_Human0.94718258
93VDR_22108803_ChIP-Seq_LS180_Human0.93672818
94DNAJC2_21179169_ChIP-ChIP_NT2_Human0.93526677
95GATA1_19941826_ChIP-Seq_K562_Human0.93007967
96RUNX1_27514584_Chip-Seq_MCF-7_Human0.92114885
97LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.91250772
98KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.91006359
99UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.90687920
100AUTS2_25519132_ChIP-Seq_293T-REX_Human0.89295907
101* SA1_27219007_Chip-Seq_Bcells_Human0.89119201
102P63_26484246_Chip-Seq_KERATINOCYTES_Human0.89041844
103ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.89019000
104ZFP281_18757296_ChIP-ChIP_E14_Mouse0.88392156
105BCOR_27268052_Chip-Seq_Bcells_Human0.86978667
106E2F1_20622854_ChIP-Seq_HELA_Human0.86395179
107TDRD3_21172665_ChIP-Seq_MCF-7_Human0.85812864
108ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.85732463
109NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.84440117
110EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.84410520
111PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.84111002
112CREB1_26743006_Chip-Seq_LNCaP_Human0.84050148
113MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.83854005
114IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.82954345
115CBP_20019798_ChIP-Seq_JUKART_Human0.82954345
116NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.82690652
117NRF2_20460467_ChIP-Seq_MEFs_Mouse0.82690652
118JARID2_20075857_ChIP-Seq_MESCs_Mouse0.81283509
119DPY_21335234_ChIP-Seq_ESCs_Mouse0.80222119
120GATA1_19941827_ChIP-Seq_MEL_Mouse0.79761723
121SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.79676382
122LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.78906254
123NANOG_20526341_ChIP-Seq_ESCs_Human0.78669670
124SOX2_21211035_ChIP-Seq_LN229_Gbm0.77413978
125GATA1_19941827_ChIP-Seq_MEL86_Mouse0.76817286
126GATA2_19941826_ChIP-Seq_K562_Human0.76418549
127KLF5_20875108_ChIP-Seq_MESCs_Mouse0.76208874
128GATA6_21074721_ChIP-Seq_CACO-2_Human0.76097565
129GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.75661286
130NR3C1_23031785_ChIP-Seq_PC12_Mouse0.74450801
131MYC_27129775_Chip-Seq_CORNEA_Mouse0.73944780
132CTCF_27219007_Chip-Seq_ERYTHROID_Human0.73934395
133MTF2_20144788_ChIP-Seq_MESCs_Mouse0.72801880
134SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.72793917
135SMC4_20622854_ChIP-Seq_HELA_Human0.72696082
136ELF1_20517297_ChIP-Seq_JURKAT_Human0.72650613
137SOX2_19829295_ChIP-Seq_ESCs_Human0.72622552
138NANOG_19829295_ChIP-Seq_ESCs_Human0.72622552
139TCF7_22412390_ChIP-Seq_EML_Mouse0.72178310
140CSB_26484114_Chip-Seq_FIBROBLAST_Human0.72178043
141CJUN_26792858_Chip-Seq_BT549_Human0.71903634
142SOX9_24532713_ChIP-Seq_HFSC_Mouse0.71698703
143KLF4_19829295_ChIP-Seq_ESCs_Human0.70866096
144HIF1A_21447827_ChIP-Seq_MCF-7_Human0.70650587
145LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.70610062
146CEBPB_22108803_ChIP-Seq_LS180_Human0.70243898
147P53_21459846_ChIP-Seq_SAOS-2_Human0.70205603
148SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.68540694

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003646_muscle_fatigue6.57237453
2MP0002837_dystrophic_cardiac_calcinosis6.16833489
3MP0000751_myopathy5.71185698
4MP0000749_muscle_degeneration5.06786425
5MP0004084_abnormal_cardiac_muscle4.46440927
6MP0004145_abnormal_muscle_electrophysio4.37080767
7MP0004036_abnormal_muscle_relaxation4.33235513
8MP0004215_abnormal_myocardial_fiber3.78577972
9MP0005330_cardiomyopathy3.40902383
10MP0004087_abnormal_muscle_fiber3.37465011
11MP0002106_abnormal_muscle_physiology3.29153076
12MP0000750_abnormal_muscle_regeneration3.14649160
13MP0000747_muscle_weakness3.01587719
14MP0004130_abnormal_muscle_cell2.97642401
15MP0005620_abnormal_muscle_contractility2.94822508
16MP0002269_muscular_atrophy2.93544196
17MP0000759_abnormal_skeletal_muscle2.78738902
18MP0005369_muscle_phenotype2.70194348
19MP0002972_abnormal_cardiac_muscle2.61671899
20MP0004484_altered_response_of2.30138197
21MP0003137_abnormal_impulse_conducting2.23895669
22MP0010630_abnormal_cardiac_muscle2.20980605
23MP0008775_abnormal_heart_ventricle2.16856977
24MP0004233_abnormal_muscle_weight2.16379442
25MP0005385_cardiovascular_system_phenoty2.16054360
26MP0001544_abnormal_cardiovascular_syste2.16054360
27MP0006036_abnormal_mitochondrial_physio2.01693399
28MP0003221_abnormal_cardiomyocyte_apopto1.84643001
29MP0002332_abnormal_exercise_endurance1.83241719
30MP0006138_congestive_heart_failure1.81944037
31MP0003828_pulmonary_edema1.60808505
32MP0005666_abnormal_adipose_tissue1.58118181
33MP0004085_abnormal_heartbeat1.52239258
34MP0004185_abnormal_adipocyte_glucose1.39308482
35MP0003950_abnormal_plasma_membrane1.38728033
36MP0004510_myositis1.33323373
37MP0002108_abnormal_muscle_morphology1.33210459
38MP0002127_abnormal_cardiovascular_syste1.29747174
39MP0000733_abnormal_muscle_development1.27181845
40MP0005670_abnormal_white_adipose1.14827754
41MP0006035_abnormal_mitochondrial_morpho1.12034433
42MP0005375_adipose_tissue_phenotype1.10364205
43MP0002234_abnormal_pharynx_morphology1.09341174
44MP0000343_altered_response_to1.07290538
45MP0005266_abnormal_metabolism1.01379008
46MP0000266_abnormal_heart_morphology0.96362583
47MP0003567_abnormal_fetal_cardiomyocyte0.90391662
48MP0003806_abnormal_nucleotide_metabolis0.90357332
49MP0002971_abnormal_brown_adipose0.89978873
50MP0001661_extended_life_span0.88862343
51MP0005165_increased_susceptibility_to0.81720420
52MP0004043_abnormal_pH_regulation0.73211109
53MP0000013_abnormal_adipose_tissue0.71685182
54MP0000372_irregular_coat_pigmentation0.70853919
55MP0003879_abnormal_hair_cell0.70337224
56MP0000230_abnormal_systemic_arterial0.67699341
57MP0003705_abnormal_hypodermis_morpholog0.67394637
58MP0004147_increased_porphyrin_level0.66312354
59MP0004134_abnormal_chest_morphology0.62703642
60MP0001346_abnormal_lacrimal_gland0.62409916
61MP0000003_abnormal_adipose_tissue0.62248141
62MP0003279_aneurysm0.61847163
63MP0002128_abnormal_blood_circulation0.59153061
64MP0002078_abnormal_glucose_homeostasis0.56720370
65MP0010368_abnormal_lymphatic_system0.55481613
66MP0008961_abnormal_basal_metabolism0.52486608
67MP0004142_abnormal_muscle_tone0.51794575
68MP0002638_abnormal_pupillary_reflex0.49503814
69MP0005319_abnormal_enzyme/_coenzyme0.48867877
70MP0002909_abnormal_adrenal_gland0.48115754
71MP0005275_abnormal_skin_tensile0.44808077
72MP0001879_abnormal_lymphatic_vessel0.44528800
73MP0005332_abnormal_amino_acid0.43525643
74MP0005334_abnormal_fat_pad0.43296681
75MP0005451_abnormal_body_composition0.40625970
76MP0005623_abnormal_meninges_morphology0.40077571
77MP0005187_abnormal_penis_morphology0.39658881
78MP0003656_abnormal_erythrocyte_physiolo0.39488949
79MP0003566_abnormal_cell_adhesion0.38901206
80MP0005083_abnormal_biliary_tract0.38132402
81MP0005166_decreased_susceptibility_to0.38001267
82MP0000767_abnormal_smooth_muscle0.36016054
83MP0005423_abnormal_somatic_nervous0.35667648
84MP0005167_abnormal_blood-brain_barrier0.35579707
85MP0005535_abnormal_body_temperature0.34905815
86MP0003959_abnormal_lean_body0.33175819
87MP0002114_abnormal_axial_skeleton0.32845729
88MP0002822_catalepsy0.32009088
89MP0003195_calcinosis0.31867127
90MP0003948_abnormal_gas_homeostasis0.30596672
91MP0005584_abnormal_enzyme/coenzyme_acti0.30592628
92MP0002896_abnormal_bone_mineralization0.29473834
93MP0002925_abnormal_cardiovascular_devel0.28897392
94MP0010030_abnormal_orbit_morphology0.28429018
95MP0005452_abnormal_adipose_tissue0.27660748
96MP0009115_abnormal_fat_cell0.27152578
97MP0002734_abnormal_mechanical_nocicepti0.26902880
98MP0009840_abnormal_foam_cell0.26723376
99MP0008569_lethality_at_weaning0.26657965
100MP0002118_abnormal_lipid_homeostasis0.26508455
101MP0001299_abnormal_eye_distance/0.26121727
102MP0008438_abnormal_cutaneous_collagen0.25495811
103MP0002067_abnormal_sensory_capabilities0.25466573
104MP0001853_heart_inflammation0.25083811
105MP0009250_abnormal_appendicular_skeleto0.25044157
106MP0004270_analgesia0.24947073
107MP0000762_abnormal_tongue_morphology0.24461547
108MP0001943_abnormal_respiration0.23763893
109MP0005376_homeostasis/metabolism_phenot0.23056602
110MP0003045_fibrosis0.22562432
111MP0001614_abnormal_blood_vessel0.22474527
112MP0009672_abnormal_birth_weight0.21095564
113MP0001784_abnormal_fluid_regulation0.20906706
114MP0002066_abnormal_motor_capabilities/c0.20380125
115MP0002163_abnormal_gland_morphology0.19842521
116MP0000579_abnormal_nail_morphology0.19439778
117MP0005645_abnormal_hypothalamus_physiol0.17924656
118MP0001727_abnormal_embryo_implantation0.17606092
119MP0002876_abnormal_thyroid_physiology0.17394059
120MP0002970_abnormal_white_adipose0.16919769
121MP0004924_abnormal_behavior0.16108050
122MP0005386_behavior/neurological_phenoty0.16108050
123MP0000249_abnormal_blood_vessel0.15389689
124MP0003984_embryonic_growth_retardation0.15325320
125MP0001502_abnormal_circadian_rhythm0.14432118
126MP0001765_abnormal_ion_homeostasis0.14275032
127MP0002088_abnormal_embryonic_growth/wei0.14250958
128MP0002009_preneoplasia0.14060877
129MP0009780_abnormal_chondrocyte_physiolo0.14040823

Predicted human phenotypes

RankGene SetZ-score
1Exercise-induced myalgia (HP:0003738)7.70045734
2Exercise-induced muscle cramps (HP:0003710)7.29745847
3Muscle hypertrophy of the lower extremities (HP:0008968)7.13664214
4Calf muscle hypertrophy (HP:0008981)7.10443492
5Muscle fiber inclusion bodies (HP:0100299)6.22263531
6Sudden death (HP:0001699)6.07145610
7Muscle fiber splitting (HP:0003555)6.02453883
8Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)6.01127155
9Myoglobinuria (HP:0002913)5.50708643
10Hyporeflexia of lower limbs (HP:0002600)5.41993434
11Nemaline bodies (HP:0003798)5.35192465
12Abnormality of the calf musculature (HP:0001430)5.30368479
13Ventricular tachycardia (HP:0004756)5.17976717
14Difficulty running (HP:0009046)4.91038450
15Type 1 muscle fiber predominance (HP:0003803)4.86724513
16EMG: myopathic abnormalities (HP:0003458)4.79288393
17Centrally nucleated skeletal muscle fibers (HP:0003687)4.74710849
18Subaortic stenosis (HP:0001682)4.64068333
19Abnormality of the left ventricular outflow tract (HP:0011103)4.64068333
20Increased connective tissue (HP:0009025)4.53656706
21Rhabdomyolysis (HP:0003201)4.39768574
22Distal arthrogryposis (HP:0005684)4.14917971
23Atrial fibrillation (HP:0005110)4.12103523
24Myotonia (HP:0002486)4.07788581
25Lipoatrophy (HP:0100578)3.97002038
26Asymmetric septal hypertrophy (HP:0001670)3.93299074
27Primary atrial arrhythmia (HP:0001692)3.85022723
28Myopathic facies (HP:0002058)3.84363607
29Muscle stiffness (HP:0003552)3.78253793
30Supraventricular tachycardia (HP:0004755)3.72313812
31Bundle branch block (HP:0011710)3.65838221
32Supraventricular arrhythmia (HP:0005115)3.63592819
33Round ear (HP:0100830)3.61862766
34Right ventricular cardiomyopathy (HP:0011663)3.53837646
35Difficulty climbing stairs (HP:0003551)3.50950353
36Dilated cardiomyopathy (HP:0001644)3.44988976
37Palpitations (HP:0001962)3.37091428
38Abnormality of skeletal muscle fiber size (HP:0012084)3.28208143
39Ulnar deviation of the wrist (HP:0003049)3.24339362
40Increased variability in muscle fiber diameter (HP:0003557)3.17965779
41Areflexia of lower limbs (HP:0002522)3.16275428
42Neck muscle weakness (HP:0000467)3.09874785
43Syncope (HP:0001279)3.06836067
44Prolonged QT interval (HP:0001657)3.01691552
45Heart block (HP:0012722)2.98200172
46Distal lower limb muscle weakness (HP:0009053)2.97442315
47Rimmed vacuoles (HP:0003805)2.91425819
48Ventricular arrhythmia (HP:0004308)2.86681663
49Abnormal atrioventricular conduction (HP:0005150)2.81709670
50Calcaneovalgus deformity (HP:0001848)2.64087174
51Abnormal mitochondria in muscle tissue (HP:0008316)2.63623125
52Atrioventricular block (HP:0001678)2.63012674
53Acute necrotizing encephalopathy (HP:0006965)2.61504678
54Limb-girdle muscle atrophy (HP:0003797)2.56783592
55Slender build (HP:0001533)2.56189058
56Weak cry (HP:0001612)2.52177040
57Absent phalangeal crease (HP:0006109)2.51011659
58Fetal akinesia sequence (HP:0001989)2.45297627
59Hepatic necrosis (HP:0002605)2.42824058
60Ventricular fibrillation (HP:0001663)2.37435290
61Deformed tarsal bones (HP:0008119)2.37040325
62Muscular dystrophy (HP:0003560)2.33433627
63Abnormality of the calcaneus (HP:0008364)2.33331863
64Frequent falls (HP:0002359)2.32711901
65EMG: neuropathic changes (HP:0003445)2.32561426
66Left ventricular hypertrophy (HP:0001712)2.28271100
67Acute encephalopathy (HP:0006846)2.26580985
68Ketoacidosis (HP:0001993)2.25822552
69Gowers sign (HP:0003391)2.25503407
70Hypoplastic ischia (HP:0003175)2.24174109
71Distal lower limb amyotrophy (HP:0008944)2.24045777
72Facial diplegia (HP:0001349)2.23478304
73Abnormal EKG (HP:0003115)2.19621490
74Hip contracture (HP:0003273)2.19218902
75Spinal rigidity (HP:0003306)2.19097871
76Generalized muscle weakness (HP:0003324)2.18131188
77Mildly elevated creatine phosphokinase (HP:0008180)2.16932094
78Progressive macrocephaly (HP:0004481)2.16294212
79Exercise intolerance (HP:0003546)2.15872442
80Hepatocellular necrosis (HP:0001404)2.15828290
81Increased muscle lipid content (HP:0009058)2.13565165
82Testicular atrophy (HP:0000029)2.12934965
83Proximal amyotrophy (HP:0007126)2.11710331
84Nonprogressive disorder (HP:0003680)2.08764993
85Malignant hyperthermia (HP:0002047)2.08285535
86Mitochondrial inheritance (HP:0001427)2.06782734
87Limb-girdle muscle weakness (HP:0003325)2.04629406
88Abnormal finger flexion creases (HP:0006143)2.02774761
89Abnormality of the foot musculature (HP:0001436)2.02585664
90Waddling gait (HP:0002515)2.01789007
91Progressive muscle weakness (HP:0003323)2.00829834
92Cerebral edema (HP:0002181)1.99402102
93Fatigable weakness (HP:0003473)1.97109483
94Abnormality of the neuromuscular junction (HP:0003398)1.97109483
95Palmoplantar keratoderma (HP:0000982)1.96846235
96Scapular winging (HP:0003691)1.95618229
97Abnormality of the ischium (HP:0003174)1.94600730
98Increased CSF lactate (HP:0002490)1.93424758
99Abnormality of the shoulder girdle musculature (HP:0001435)1.91541466
100Hypoglycemic coma (HP:0001325)1.90026294
101Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.89403798
102Bulbar palsy (HP:0001283)1.89065579
103Increased intramyocellular lipid droplets (HP:0012240)1.88325829
104Hyperkalemia (HP:0002153)1.86725322
105Abnormality of alanine metabolism (HP:0010916)1.86163833
106Hyperalaninemia (HP:0003348)1.86163833
107Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.86163833
108Abnormality of dicarboxylic acid metabolism (HP:0010995)1.85386171
109Dicarboxylic aciduria (HP:0003215)1.85386171
110Conjunctival hamartoma (HP:0100780)1.84631243
111Foot dorsiflexor weakness (HP:0009027)1.84131524
112Lower limb amyotrophy (HP:0007210)1.82708858
113Paralysis (HP:0003470)1.78102098
114Abnormality of the hip-girdle musculature (HP:0001445)1.77175544
115Abnormality of the musculature of the pelvis (HP:0001469)1.77175544
116Ragged-red muscle fibers (HP:0003200)1.75704546
117Respiratory insufficiency due to muscle weakness (HP:0002747)1.73525568
118Pelvic girdle muscle weakness (HP:0003749)1.72278017
119Long clavicles (HP:0000890)1.69653291
120Shoulder girdle muscle weakness (HP:0003547)1.64354860
121Popliteal pterygium (HP:0009756)1.61709061
122Ulnar deviation of finger (HP:0009465)1.59267694
123Metatarsus adductus (HP:0001840)1.56098525
124Type 2 muscle fiber atrophy (HP:0003554)1.46675363
125Limited hip movement (HP:0008800)1.43143813
126Ulnar deviation of the hand or of fingers of the hand (HP:0001193)1.39226407
127Muscle fiber atrophy (HP:0100295)1.35912886
128Steppage gait (HP:0003376)1.28900620
129Oligomenorrhea (HP:0000876)1.26992853
130Congenital hip dislocation (HP:0001374)1.26940531
131Abnormality of potassium homeostasis (HP:0011042)1.23670011
132Neonatal hypotonia (HP:0001319)1.17978134
133Short palpebral fissure (HP:0012745)1.16429863

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN7.15368829
2OBSCN6.13915158
3PHKG24.99602764
4PHKG14.99602764
5PDK33.18412853
6PDK43.18412853
7DMPK2.63266877
8BCKDK2.52625958
9PINK12.46003442
10TRIB32.45665340
11LMTK22.44856000
12NEK12.36002223
13MUSK2.25783418
14MYLK2.25051156
15NME12.21002738
16PIK3CA2.08114834
17PKN22.03405676
18PDK21.98543585
19PIK3CG1.87998319
20MAP2K31.84767806
21MAP3K71.55808719
22MAPK121.34241929
23TIE11.28556634
24STK241.21547422
25GRK70.99945017
26MAPKAPK30.95806843
27PRKD10.92973823
28PRKAA10.92174166
29DYRK1B0.92043126
30CAMK2D0.89686099
31PRKAA20.89477190
32PAK30.88035595
33MOS0.85866879
34ILK0.83413596
35MARK10.82576394
36MAP3K130.79055023
37MAP3K30.77643090
38MAP2K40.77344645
39TRPM70.77305124
40CCNB10.75234286
41ZAK0.74602799
42MAP2K60.72572349
43RIPK10.69019057
44MAP3K50.68473583
45ROCK10.67869402
46ERBB30.67118064
47NEK90.66774851
48PKN10.66533931
49LIMK10.63533878
50INSRR0.56728963
51EPHB10.56357629
52FLT30.55106465
53KSR20.51452638
54STK40.49491770
55CAMK2G0.49030966
56AKT20.48050408
57NME20.48012108
58CAMK40.47592008
59STK38L0.47159933
60SGK20.46429341
61CDC42BPA0.45450083
62PRKACB0.45049491
63MAP2K10.43900362
64CAMK2B0.42600812
65WNK40.41789530
66PDGFRA0.41003748
67ROCK20.38965316
68TGFBR20.38940492
69CAMK2A0.38180496
70MAPK110.37961010
71STK380.36344521
72PRPF4B0.34571415
73TAOK10.34546849
74DAPK30.34320709
75RPS6KC10.34073263
76RPS6KL10.34073263
77PRKACA0.33233209
78TBK10.33089795
79MAP3K110.32873623
80FRK0.31164120
81WNK10.30959278
82PDPK10.30617327
83PTK60.29980795
84ICK0.29543291
85RPS6KA60.27863511
86RPS6KB10.27294180
87PRKACG0.26488530
88SIK10.26190664
89CAMK10.25977711
90TAOK20.25612573
91MAPK130.25375778
92SGK4940.24920102
93SGK2230.24920102
94PDK10.24800586
95KDR0.24324149
96SGK10.24007976
97PTK2B0.23195574
98RPS6KA10.22300563
99DAPK20.21799468
100PRKG10.21462898
101MAP3K10.19817364
102RPS6KA30.19094029
103RAF10.19083544
104ZAP700.17079615
105RPS6KB20.17060001
106MAPK100.16692770
107MAPK70.15218746
108MARK20.14802739
109MTOR0.14796286
110PRKCH0.14726820
111ARAF0.14695789
112LATS20.14274264
113BLK0.13890650
114SGK30.13626349
115MARK30.12802771
116EEF2K0.12577965
117PRKCE0.12138202
118KSR10.12077395
119MAPK40.10438836
120STK110.10369803
121FGFR30.09613484
122MAP3K60.09419449
123LATS10.09320886
124IRAK20.09186953
125FER0.08459390
126LRRK20.08385288
127PRKD30.08060464
128JAK10.07677423
129RPS6KA20.07646562
130NLK0.06827026
131PAK60.06282139
132RET0.06062987
133MAPK80.03271448
134CDK190.03123637
135EPHA30.02964583

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000205.67870540
2Cardiac muscle contraction_Homo sapiens_hsa042604.28140596
32-Oxocarboxylic acid metabolism_Homo sapiens_hsa012104.15253883
4Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.80148679
5Dilated cardiomyopathy_Homo sapiens_hsa054143.64249627
6Propanoate metabolism_Homo sapiens_hsa006403.25849255
7Parkinsons disease_Homo sapiens_hsa050123.23300372
8Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.17917191
9Oxidative phosphorylation_Homo sapiens_hsa001903.13049719
10Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.78264305
11Fatty acid degradation_Homo sapiens_hsa000712.58593497
12Carbon metabolism_Homo sapiens_hsa012002.49783038
13Alzheimers disease_Homo sapiens_hsa050102.48972854
14Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.31970870
15Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.22564372
16Huntingtons disease_Homo sapiens_hsa050161.94790109
17Fatty acid metabolism_Homo sapiens_hsa012121.92662655
18Pyruvate metabolism_Homo sapiens_hsa006201.78993645
19Viral myocarditis_Homo sapiens_hsa054161.70682864
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.65988051
21Starch and sucrose metabolism_Homo sapiens_hsa005001.54504390
22Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.48946436
23Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.43662396
24Cyanoamino acid metabolism_Homo sapiens_hsa004601.41401911
25Glucagon signaling pathway_Homo sapiens_hsa049221.35372375
26Insulin resistance_Homo sapiens_hsa049311.31047077
27Insulin signaling pathway_Homo sapiens_hsa049101.24981353
28Biosynthesis of amino acids_Homo sapiens_hsa012301.22258603
29Nitrogen metabolism_Homo sapiens_hsa009101.22047394
30Adipocytokine signaling pathway_Homo sapiens_hsa049201.20202641
31Butanoate metabolism_Homo sapiens_hsa006501.19679496
32Long-term potentiation_Homo sapiens_hsa047201.04967473
33Oxytocin signaling pathway_Homo sapiens_hsa049211.00083747
34Fatty acid elongation_Homo sapiens_hsa000620.99910336
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.99315466
36Calcium signaling pathway_Homo sapiens_hsa040200.98176501
37cGMP-PKG signaling pathway_Homo sapiens_hsa040220.96696577
38PPAR signaling pathway_Homo sapiens_hsa033200.95473483
39AMPK signaling pathway_Homo sapiens_hsa041520.94696006
40Galactose metabolism_Homo sapiens_hsa000520.89273926
41Arginine and proline metabolism_Homo sapiens_hsa003300.88588511
42Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.86803235
43Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.86623074
44Circadian rhythm_Homo sapiens_hsa047100.85045230
45Arginine biosynthesis_Homo sapiens_hsa002200.78451621
46Fructose and mannose metabolism_Homo sapiens_hsa000510.75204602
47Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.72350292
48beta-Alanine metabolism_Homo sapiens_hsa004100.69862528
49HIF-1 signaling pathway_Homo sapiens_hsa040660.68567262
50Focal adhesion_Homo sapiens_hsa045100.68147301
51Vascular smooth muscle contraction_Homo sapiens_hsa042700.67809940
52Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.67698652
53Tight junction_Homo sapiens_hsa045300.65085465
54Tryptophan metabolism_Homo sapiens_hsa003800.63067641
55Type II diabetes mellitus_Homo sapiens_hsa049300.55249586
56Central carbon metabolism in cancer_Homo sapiens_hsa052300.55199912
57Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.54710789
58Lysine degradation_Homo sapiens_hsa003100.53447891
59Fatty acid biosynthesis_Homo sapiens_hsa000610.52630621
60Peroxisome_Homo sapiens_hsa041460.49829507
61Amphetamine addiction_Homo sapiens_hsa050310.49579657
62Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.49466510
63Longevity regulating pathway - mammal_Homo sapiens_hsa042110.48652838
64Gastric acid secretion_Homo sapiens_hsa049710.48440831
65Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.45040879
66Phenylalanine metabolism_Homo sapiens_hsa003600.42812004
67Renin secretion_Homo sapiens_hsa049240.41780828
68Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.41554502
69Long-term depression_Homo sapiens_hsa047300.40886857
70Salivary secretion_Homo sapiens_hsa049700.39112617
71Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.37989916
72Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.36757457
73Thyroid hormone signaling pathway_Homo sapiens_hsa049190.33730469
74Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.33620735
75Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.33594943
76Regulation of autophagy_Homo sapiens_hsa041400.33282806
77Insulin secretion_Homo sapiens_hsa049110.33245057
78GnRH signaling pathway_Homo sapiens_hsa049120.29934711
79Histidine metabolism_Homo sapiens_hsa003400.29035854
80Pentose phosphate pathway_Homo sapiens_hsa000300.28343047
81Metabolic pathways_Homo sapiens_hsa011000.27267869
82FoxO signaling pathway_Homo sapiens_hsa040680.26478021
83VEGF signaling pathway_Homo sapiens_hsa043700.26052738
84cAMP signaling pathway_Homo sapiens_hsa040240.25625011
85Adherens junction_Homo sapiens_hsa045200.23520727
86Olfactory transduction_Homo sapiens_hsa047400.22220606
87mTOR signaling pathway_Homo sapiens_hsa041500.22077472
88Amoebiasis_Homo sapiens_hsa051460.21993220
89Sulfur relay system_Homo sapiens_hsa041220.21659366
90Fat digestion and absorption_Homo sapiens_hsa049750.20848520
91Regulation of actin cytoskeleton_Homo sapiens_hsa048100.20521886
92ECM-receptor interaction_Homo sapiens_hsa045120.20355075
93Renal cell carcinoma_Homo sapiens_hsa052110.19906977
94Platelet activation_Homo sapiens_hsa046110.18551298
95Neurotrophin signaling pathway_Homo sapiens_hsa047220.18477042
96Cysteine and methionine metabolism_Homo sapiens_hsa002700.17986761
97Glioma_Homo sapiens_hsa052140.17961669
98Aldosterone synthesis and secretion_Homo sapiens_hsa049250.17657628
99Leukocyte transendothelial migration_Homo sapiens_hsa046700.17294800
100MAPK signaling pathway_Homo sapiens_hsa040100.14480671
101Proteoglycans in cancer_Homo sapiens_hsa052050.13091242
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.12681504
103Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.11547440
104Purine metabolism_Homo sapiens_hsa002300.10559580
105Melanogenesis_Homo sapiens_hsa049160.10455617
106T cell receptor signaling pathway_Homo sapiens_hsa046600.09894520
107Tyrosine metabolism_Homo sapiens_hsa003500.09657598
108Circadian entrainment_Homo sapiens_hsa047130.09345796
109Non-small cell lung cancer_Homo sapiens_hsa052230.09196948
110Oocyte meiosis_Homo sapiens_hsa041140.08240802
111Pancreatic secretion_Homo sapiens_hsa049720.07786393
112Dorso-ventral axis formation_Homo sapiens_hsa043200.05589085
113Cholinergic synapse_Homo sapiens_hsa047250.04693850
114alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.04376866
115AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.03490253
116Glycerolipid metabolism_Homo sapiens_hsa005610.03147882
117Gap junction_Homo sapiens_hsa045400.02589842
118Notch signaling pathway_Homo sapiens_hsa04330-0.0629872
119Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964-0.0574908
120ABC transporters_Homo sapiens_hsa02010-0.0393713
121Linoleic acid metabolism_Homo sapiens_hsa00591-0.0199378
122Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0154460
123Toxoplasmosis_Homo sapiens_hsa05145-0.0115582
124Bile secretion_Homo sapiens_hsa04976-0.0089786

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