Rank | Gene Set | Z-score |
---|---|---|
1 | sarcomere organization (GO:0045214) | 6.73673567 |
2 | cardiac myofibril assembly (GO:0055003) | 6.35265893 |
3 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 6.35030093 |
4 | carnitine shuttle (GO:0006853) | 6.20945519 |
5 | actin-myosin filament sliding (GO:0033275) | 6.17448033 |
6 | muscle filament sliding (GO:0030049) | 6.17448033 |
7 | tricarboxylic acid cycle (GO:0006099) | 5.98753421 |
8 | myofibril assembly (GO:0030239) | 5.97265891 |
9 | fatty acid transmembrane transport (GO:1902001) | 5.82987662 |
10 | regulation of sequestering of triglyceride (GO:0010889) | 5.77467908 |
11 | regulation of skeletal muscle contraction (GO:0014819) | 5.66562132 |
12 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 5.64142571 |
13 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 5.60424958 |
14 | response to muscle activity (GO:0014850) | 5.49482374 |
15 | response to inactivity (GO:0014854) | 5.49400413 |
16 | carnitine transmembrane transport (GO:1902603) | 5.43804351 |
17 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 5.43771573 |
18 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 5.27583531 |
19 | actin-mediated cell contraction (GO:0070252) | 5.12974466 |
20 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 5.02576926 |
21 | carnitine transport (GO:0015879) | 5.01031643 |
22 | amino-acid betaine transport (GO:0015838) | 5.01031643 |
23 | cardiac muscle contraction (GO:0060048) | 4.94677071 |
24 | plasma membrane repair (GO:0001778) | 4.84244712 |
25 | regulation of relaxation of muscle (GO:1901077) | 4.81684388 |
26 | skeletal muscle fiber development (GO:0048741) | 4.70615960 |
27 | cardiac muscle cell development (GO:0055013) | 4.58282130 |
28 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 4.54398805 |
29 | regulation of actin filament-based movement (GO:1903115) | 4.52830927 |
30 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 4.51658408 |
31 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 4.51597924 |
32 | myotube cell development (GO:0014904) | 4.51292896 |
33 | regulation of cell communication by electrical coupling (GO:0010649) | 4.33873076 |
34 | actomyosin structure organization (GO:0031032) | 4.33551711 |
35 | cardiac cell development (GO:0055006) | 4.32444952 |
36 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 4.31802136 |
37 | muscle fiber development (GO:0048747) | 4.31073038 |
38 | heart trabecula formation (GO:0060347) | 4.21942269 |
39 | striated muscle contraction (GO:0006941) | 4.19513120 |
40 | creatine metabolic process (GO:0006600) | 4.15759424 |
41 | cardiac muscle tissue morphogenesis (GO:0055008) | 4.13749662 |
42 | cardiac muscle hypertrophy (GO:0003300) | 4.12411550 |
43 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.06587801 |
44 | glucan catabolic process (GO:0009251) | 4.02419388 |
45 | regulation of cofactor metabolic process (GO:0051193) | 4.01679605 |
46 | regulation of coenzyme metabolic process (GO:0051196) | 4.01679605 |
47 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.99336553 |
48 | fatty acid beta-oxidation (GO:0006635) | 3.98592476 |
49 | lipid particle organization (GO:0034389) | 3.97216359 |
50 | striated muscle hypertrophy (GO:0014897) | 3.96993894 |
51 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.96512502 |
52 | regulation of fatty acid oxidation (GO:0046320) | 3.89046723 |
53 | regulation of sarcomere organization (GO:0060297) | 3.88789252 |
54 | actin filament-based movement (GO:0030048) | 3.86160859 |
55 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 3.85670136 |
56 | muscle tissue morphogenesis (GO:0060415) | 3.85395937 |
57 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.84298508 |
58 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.83543577 |
59 | glycogen biosynthetic process (GO:0005978) | 3.82962191 |
60 | glucan biosynthetic process (GO:0009250) | 3.82962191 |
61 | brown fat cell differentiation (GO:0050873) | 3.80497454 |
62 | cellular polysaccharide catabolic process (GO:0044247) | 3.77898383 |
63 | neuronal action potential propagation (GO:0019227) | 3.76729095 |
64 | regulation of striated muscle contraction (GO:0006942) | 3.74306961 |
65 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.69338083 |
66 | quaternary ammonium group transport (GO:0015697) | 3.67368002 |
67 | skeletal muscle tissue development (GO:0007519) | 3.65003225 |
68 | heart process (GO:0003015) | 3.64294887 |
69 | heart contraction (GO:0060047) | 3.64294887 |
70 | low-density lipoprotein particle clearance (GO:0034383) | 3.64258916 |
71 | positive regulation of fatty acid oxidation (GO:0046321) | 3.60606262 |
72 | adult heart development (GO:0007512) | 3.58832130 |
73 | biotin metabolic process (GO:0006768) | 3.54708278 |
74 | regulation of the force of heart contraction (GO:0002026) | 3.54653833 |
75 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 3.52700697 |
76 | regulation of calcium ion transmembrane transport (GO:1903169) | 3.52700697 |
77 | 2-oxoglutarate metabolic process (GO:0006103) | 3.52665045 |
78 | muscle hypertrophy (GO:0014896) | 3.51764655 |
79 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 3.48681044 |
80 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 3.48681044 |
81 | polysaccharide catabolic process (GO:0000272) | 3.46363692 |
82 | valine metabolic process (GO:0006573) | 3.44236645 |
83 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 3.42214878 |
84 | NADH metabolic process (GO:0006734) | 3.42111961 |
85 | ubiquinone biosynthetic process (GO:0006744) | 3.41830974 |
86 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.41803473 |
87 | striated muscle atrophy (GO:0014891) | 3.41032407 |
88 | aspartate family amino acid catabolic process (GO:0009068) | 3.40836639 |
89 | skeletal muscle contraction (GO:0003009) | 3.36920781 |
90 | positive regulation of cation channel activity (GO:2001259) | 3.36515288 |
91 | skeletal muscle adaptation (GO:0043501) | 3.34710996 |
92 | muscle cell cellular homeostasis (GO:0046716) | 3.32340532 |
93 | fatty acid catabolic process (GO:0009062) | 3.27953409 |
94 | muscle contraction (GO:0006936) | 3.27761084 |
95 | regulation of ATP catabolic process (GO:1903289) | 3.27670495 |
96 | regulation of ATPase activity (GO:0043462) | 3.27670495 |
97 | regulation of sulfur metabolic process (GO:0042762) | 3.27601332 |
98 | regulation of membrane repolarization (GO:0060306) | 3.26535557 |
99 | skeletal muscle tissue regeneration (GO:0043403) | 3.24777862 |
100 | intracellular lipid transport (GO:0032365) | 3.23296914 |
101 | fatty acid oxidation (GO:0019395) | 3.22285283 |
102 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.21147023 |
103 | otic vesicle formation (GO:0030916) | 3.20347190 |
104 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.19090145 |
105 | lipid oxidation (GO:0034440) | 3.17547725 |
106 | triglyceride catabolic process (GO:0019433) | 3.17506629 |
107 | succinate metabolic process (GO:0006105) | 3.11999281 |
108 | muscle structure development (GO:0061061) | 3.11826194 |
109 | cell communication involved in cardiac conduction (GO:0086065) | 3.10990465 |
110 | muscle atrophy (GO:0014889) | 3.10234969 |
111 | relaxation of muscle (GO:0090075) | 3.09836807 |
112 | muscle organ development (GO:0007517) | 3.09749865 |
113 | muscle system process (GO:0003012) | 3.07531379 |
114 | response to activity (GO:0014823) | 3.05728344 |
115 | negative regulation of potassium ion transport (GO:0043267) | 3.05657763 |
116 | glycogen metabolic process (GO:0005977) | 3.05537047 |
117 | ubiquinone metabolic process (GO:0006743) | 3.04603507 |
118 | cardiac muscle adaptation (GO:0014887) | 3.02904441 |
119 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 3.02904441 |
120 | muscle hypertrophy in response to stress (GO:0003299) | 3.02904441 |
121 | muscle adaptation (GO:0043500) | 3.02656695 |
122 | response to caffeine (GO:0031000) | 3.02644922 |
123 | regulation of muscle contraction (GO:0006937) | 3.02445535 |
124 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.02299615 |
125 | neuromuscular synaptic transmission (GO:0007274) | 3.02149761 |
126 | regulation of muscle system process (GO:0090257) | 3.01720780 |
127 | regulation of cardiac muscle contraction (GO:0055117) | 3.00462915 |
128 | striated muscle adaptation (GO:0014888) | 3.00211082 |
129 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.99776575 |
130 | regulation of cardiac muscle cell contraction (GO:0086004) | 2.99565321 |
131 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 2.99054352 |
132 | glycogen catabolic process (GO:0005980) | 2.98290472 |
133 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.96640992 |
134 | branched-chain amino acid catabolic process (GO:0009083) | 2.95409822 |
135 | response to epinephrine (GO:0071871) | 2.93323415 |
136 | relaxation of cardiac muscle (GO:0055119) | 2.93062749 |
137 | cellular response to epinephrine stimulus (GO:0071872) | 2.87693889 |
138 | cardiac muscle cell action potential (GO:0086001) | 2.84053287 |
139 | respiratory electron transport chain (GO:0022904) | 2.83797457 |
140 | branched-chain amino acid metabolic process (GO:0009081) | 2.82815192 |
141 | striated muscle cell development (GO:0055002) | 2.81082866 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 8.15309744 |
2 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 4.34835681 |
3 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 3.53773983 |
4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.17540584 |
5 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 3.03375435 |
6 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 3.03375435 |
7 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.87920648 |
8 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.65768305 |
9 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.63825905 |
10 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 2.42022307 |
11 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.33433822 |
12 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.31073686 |
13 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.25419682 |
14 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.22873057 |
15 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.22605765 |
16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.12677244 |
17 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.08884321 |
18 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.04097107 |
19 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.03527944 |
20 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.02141423 |
21 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.94246202 |
22 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.92922724 |
23 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.90647306 |
24 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.89169397 |
25 | * ER_23166858_ChIP-Seq_MCF-7_Human | 1.79042447 |
26 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.74541745 |
27 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.71789506 |
28 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.71727336 |
29 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 1.67077166 |
30 | FUS_26573619_Chip-Seq_HEK293_Human | 1.63586298 |
31 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.62668042 |
32 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.56053443 |
33 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.55706262 |
34 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.53374156 |
35 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.53104126 |
36 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.52647876 |
37 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.52248016 |
38 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.50243453 |
39 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.49490894 |
40 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.48962239 |
41 | GATA1_22025678_ChIP-Seq_K562_Human | 1.48310085 |
42 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.46870323 |
43 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.44244617 |
44 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.44067777 |
45 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.42430317 |
46 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.42325017 |
47 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.41890495 |
48 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.41441839 |
49 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.37657414 |
50 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.36074518 |
51 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.36074518 |
52 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.35666471 |
53 | CJUN_26792858_Chip-Seq_BT549_Human | 1.35279333 |
54 | P300_19829295_ChIP-Seq_ESCs_Human | 1.35237583 |
55 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.34302952 |
56 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.34294056 |
57 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.33231007 |
58 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.31891477 |
59 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.30788463 |
60 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.29835726 |
61 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.28495064 |
62 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.28025320 |
63 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.27391248 |
64 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.24374067 |
65 | STAT3_23295773_ChIP-Seq_U87_Human | 1.24295238 |
66 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.23852999 |
67 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.23296447 |
68 | AR_25329375_ChIP-Seq_VCAP_Human | 1.21177454 |
69 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.19829212 |
70 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.19441847 |
71 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.19367549 |
72 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.18134096 |
73 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.17984799 |
74 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.17912016 |
75 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.17699337 |
76 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.17683984 |
77 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.17067562 |
78 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.17037163 |
79 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.15655025 |
80 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.14324968 |
81 | * GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.12120439 |
82 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.11305366 |
83 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.11101115 |
84 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.10843352 |
85 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.10673379 |
86 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.10180560 |
87 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.10122674 |
88 | * NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.10049744 |
89 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.09201290 |
90 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.06060688 |
91 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.04840925 |
92 | * CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.04160999 |
93 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.03555666 |
94 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.03058809 |
95 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.02849361 |
96 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.02583437 |
97 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.02389364 |
98 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.00140590 |
99 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.99689175 |
100 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.98862304 |
101 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.98246971 |
102 | * PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.98209908 |
103 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.97714710 |
104 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.97393320 |
105 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.96886957 |
106 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.96591137 |
107 | NFYB_21822215_ChIP-Seq_K562_Human | 0.96501652 |
108 | * PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.96241968 |
109 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.95265614 |
110 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.94963082 |
111 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.94510056 |
112 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.94021890 |
113 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.93917610 |
114 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.93846923 |
115 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.93752145 |
116 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.93637474 |
117 | TBL1_22424771_ChIP-Seq_293T_Human | 0.93580993 |
118 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93499452 |
119 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.92810335 |
120 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.92078543 |
121 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.91659073 |
122 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.91545437 |
123 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.91394704 |
124 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.91394704 |
125 | * MYC_19829295_ChIP-Seq_ESCs_Human | 0.91018003 |
126 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90938376 |
127 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.90938376 |
128 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.90650791 |
129 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.90477974 |
130 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.85594689 |
131 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.84287930 |
132 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.84186061 |
133 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.84022169 |
134 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.83150259 |
135 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.82826166 |
136 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.82811671 |
137 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.82536785 |
138 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.81827071 |
139 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.81162352 |
140 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.80408125 |
141 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.78178524 |
142 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.78033708 |
143 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.77634758 |
144 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.77419409 |
145 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.77228805 |
146 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.76299575 |
147 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.76299575 |
148 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.76046123 |
149 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 0.75882362 |
150 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.74403396 |
151 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.73745219 |
152 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.73680707 |
153 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.73628458 |
154 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.73182944 |
155 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73093246 |
156 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.72789209 |
157 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.72197441 |
158 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.71589316 |
159 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.70925034 |
160 | GATA1_19941826_ChIP-Seq_K562_Human | 0.70121760 |
161 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.70101067 |
162 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.69808594 |
163 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.69612639 |
164 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.69596438 |
165 | VDR_22108803_ChIP-Seq_LS180_Human | 0.68979969 |
166 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.68439805 |
167 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.68188113 |
168 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.67772665 |
169 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.67756323 |
170 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.67519880 |
171 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.67463900 |
172 | CBP_21632823_ChIP-Seq_H3396_Human | 0.67050564 |
173 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.66703531 |
174 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.66679871 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002837_dystrophic_cardiac_calcinosis | 5.83643713 |
2 | MP0003646_muscle_fatigue | 5.39080517 |
3 | MP0000751_myopathy | 4.83511958 |
4 | MP0004084_abnormal_cardiac_muscle | 4.39757406 |
5 | MP0004215_abnormal_myocardial_fiber | 3.89219459 |
6 | MP0004130_abnormal_muscle_cell | 3.81765142 |
7 | MP0005670_abnormal_white_adipose | 3.75825429 |
8 | MP0004036_abnormal_muscle_relaxation | 3.74251519 |
9 | MP0000749_muscle_degeneration | 3.74135017 |
10 | MP0005330_cardiomyopathy | 3.21593256 |
11 | MP0005666_abnormal_adipose_tissue | 2.97132081 |
12 | MP0004087_abnormal_muscle_fiber | 2.84013315 |
13 | MP0000750_abnormal_muscle_regeneration | 2.72443435 |
14 | MP0008775_abnormal_heart_ventricle | 2.70281719 |
15 | MP0005620_abnormal_muscle_contractility | 2.69872167 |
16 | MP0002972_abnormal_cardiac_muscle | 2.64000807 |
17 | MP0004145_abnormal_muscle_electrophysio | 2.57097607 |
18 | MP0004185_abnormal_adipocyte_glucose | 2.44152360 |
19 | MP0002106_abnormal_muscle_physiology | 2.37041746 |
20 | MP0004484_altered_response_of | 2.25233404 |
21 | MP0006138_congestive_heart_failure | 2.22774489 |
22 | MP0001544_abnormal_cardiovascular_syste | 2.22193330 |
23 | MP0005385_cardiovascular_system_phenoty | 2.22193330 |
24 | MP0010630_abnormal_cardiac_muscle | 2.13967621 |
25 | MP0005375_adipose_tissue_phenotype | 2.07975703 |
26 | MP0003828_pulmonary_edema | 2.05948893 |
27 | MP0002269_muscular_atrophy | 2.03522603 |
28 | MP0005451_abnormal_body_composition | 2.02765298 |
29 | MP0003137_abnormal_impulse_conducting | 2.00458849 |
30 | MP0000759_abnormal_skeletal_muscle | 1.98367355 |
31 | MP0000747_muscle_weakness | 1.94897808 |
32 | MP0005369_muscle_phenotype | 1.93445757 |
33 | MP0008438_abnormal_cutaneous_collagen | 1.82643794 |
34 | MP0005410_abnormal_fertilization | 1.75454402 |
35 | MP0003950_abnormal_plasma_membrane | 1.73335585 |
36 | MP0004272_abnormal_basement_membrane | 1.60520163 |
37 | MP0000013_abnormal_adipose_tissue | 1.60180615 |
38 | MP0002332_abnormal_exercise_endurance | 1.57856506 |
39 | MP0004085_abnormal_heartbeat | 1.56962786 |
40 | MP0003221_abnormal_cardiomyocyte_apopto | 1.55152014 |
41 | MP0006036_abnormal_mitochondrial_physio | 1.52425716 |
42 | MP0004233_abnormal_muscle_weight | 1.51514681 |
43 | MP0005275_abnormal_skin_tensile | 1.46566562 |
44 | MP0004510_myositis | 1.44632215 |
45 | MP0002971_abnormal_brown_adipose | 1.44205215 |
46 | MP0000343_altered_response_to | 1.39872477 |
47 | MP0004270_analgesia | 1.38705189 |
48 | MP0000003_abnormal_adipose_tissue | 1.26311012 |
49 | MP0002127_abnormal_cardiovascular_syste | 1.24321284 |
50 | MP0001879_abnormal_lymphatic_vessel | 1.20081252 |
51 | MP0003279_aneurysm | 1.18759002 |
52 | MP0002108_abnormal_muscle_morphology | 1.16179060 |
53 | MP0005623_abnormal_meninges_morphology | 1.13839846 |
54 | MP0009115_abnormal_fat_cell | 1.03850148 |
55 | MP0003045_fibrosis | 1.02429507 |
56 | MP0001661_extended_life_span | 0.96294557 |
57 | MP0005165_increased_susceptibility_to | 0.95373576 |
58 | MP0000230_abnormal_systemic_arterial | 0.94712795 |
59 | MP0010368_abnormal_lymphatic_system | 0.93945858 |
60 | MP0000266_abnormal_heart_morphology | 0.91562909 |
61 | MP0005334_abnormal_fat_pad | 0.90987306 |
62 | MP0004147_increased_porphyrin_level | 0.90410150 |
63 | MP0000372_irregular_coat_pigmentation | 0.89990041 |
64 | MP0002638_abnormal_pupillary_reflex | 0.88412989 |
65 | MP0004142_abnormal_muscle_tone | 0.87070541 |
66 | MP0001984_abnormal_olfaction | 0.81234428 |
67 | MP0003566_abnormal_cell_adhesion | 0.80578061 |
68 | MP0003705_abnormal_hypodermis_morpholog | 0.75769238 |
69 | MP0006276_abnormal_autonomic_nervous | 0.74805678 |
70 | MP0002876_abnormal_thyroid_physiology | 0.72532839 |
71 | MP0002128_abnormal_blood_circulation | 0.71541603 |
72 | MP0005535_abnormal_body_temperature | 0.71374203 |
73 | MP0002272_abnormal_nervous_system | 0.70156595 |
74 | MP0008877_abnormal_DNA_methylation | 0.70046780 |
75 | MP0002118_abnormal_lipid_homeostasis | 0.68081420 |
76 | MP0005551_abnormal_eye_electrophysiolog | 0.67792453 |
77 | MP0009745_abnormal_behavioral_response | 0.67715831 |
78 | MP0000733_abnormal_muscle_development | 0.67549674 |
79 | MP0002970_abnormal_white_adipose | 0.66171639 |
80 | MP0001529_abnormal_vocalization | 0.65573830 |
81 | MP0001501_abnormal_sleep_pattern | 0.65289130 |
82 | MP0005266_abnormal_metabolism | 0.64770666 |
83 | MP0002078_abnormal_glucose_homeostasis | 0.61251458 |
84 | MP0005645_abnormal_hypothalamus_physiol | 0.60045996 |
85 | MP0004924_abnormal_behavior | 0.59681610 |
86 | MP0005386_behavior/neurological_phenoty | 0.59681610 |
87 | MP0009384_cardiac_valve_regurgitation | 0.59633942 |
88 | MP0003567_abnormal_fetal_cardiomyocyte | 0.59457862 |
89 | MP0005253_abnormal_eye_physiology | 0.59251254 |
90 | MP0008961_abnormal_basal_metabolism | 0.58683498 |
91 | MP0010329_abnormal_lipoprotein_level | 0.58305453 |
92 | MP0003879_abnormal_hair_cell | 0.57685623 |
93 | MP0002234_abnormal_pharynx_morphology | 0.56592648 |
94 | MP0009046_muscle_twitch | 0.56490122 |
95 | MP0001727_abnormal_embryo_implantation | 0.56385289 |
96 | MP0002822_catalepsy | 0.55824307 |
97 | MP0008569_lethality_at_weaning | 0.55260411 |
98 | MP0005319_abnormal_enzyme/_coenzyme | 0.54995349 |
99 | MP0001486_abnormal_startle_reflex | 0.54943274 |
100 | MP0005332_abnormal_amino_acid | 0.54609125 |
101 | MP0002909_abnormal_adrenal_gland | 0.53817125 |
102 | MP0005595_abnormal_vascular_smooth | 0.52541982 |
103 | MP0006035_abnormal_mitochondrial_morpho | 0.52286590 |
104 | MP0002067_abnormal_sensory_capabilities | 0.52050251 |
105 | MP0005167_abnormal_blood-brain_barrier | 0.51316318 |
106 | MP0000767_abnormal_smooth_muscle | 0.50395808 |
107 | MP0005646_abnormal_pituitary_gland | 0.49935679 |
108 | MP0001485_abnormal_pinna_reflex | 0.49659190 |
109 | MP0003959_abnormal_lean_body | 0.48511200 |
110 | MP0002734_abnormal_mechanical_nocicepti | 0.47931321 |
111 | MP0002064_seizures | 0.47587810 |
112 | MP0001299_abnormal_eye_distance/ | 0.46381830 |
113 | MP0005423_abnormal_somatic_nervous | 0.45428989 |
114 | MP0006072_abnormal_retinal_apoptosis | 0.44848865 |
115 | MP0005452_abnormal_adipose_tissue | 0.44719338 |
116 | MP0003011_delayed_dark_adaptation | 0.43307282 |
117 | MP0003136_yellow_coat_color | 0.42671059 |
118 | MP0009780_abnormal_chondrocyte_physiolo | 0.42628730 |
119 | MP0003191_abnormal_cellular_cholesterol | 0.42413561 |
120 | MP0001958_emphysema | 0.41761256 |
121 | MP0003948_abnormal_gas_homeostasis | 0.41684318 |
122 | MP0003724_increased_susceptibility_to | 0.41584331 |
123 | MP0004043_abnormal_pH_regulation | 0.41573937 |
124 | MP0000249_abnormal_blood_vessel | 0.41399398 |
125 | MP0008872_abnormal_physiological_respon | 0.40161390 |
126 | MP0001614_abnormal_blood_vessel | 0.40152662 |
127 | MP0002066_abnormal_motor_capabilities/c | 0.39347778 |
128 | MP0005187_abnormal_penis_morphology | 0.38693165 |
129 | MP0003698_abnormal_male_reproductive | 0.38535847 |
130 | MP0005503_abnormal_tendon_morphology | 0.38450583 |
131 | MP0003635_abnormal_synaptic_transmissio | 0.38330765 |
132 | MP0002160_abnormal_reproductive_system | 0.37171645 |
133 | MP0005448_abnormal_energy_balance | 0.37038487 |
134 | MP0002925_abnormal_cardiovascular_devel | 0.36574446 |
135 | MP0002295_abnormal_pulmonary_circulatio | 0.36156609 |
136 | MP0004134_abnormal_chest_morphology | 0.35773928 |
137 | MP0002166_altered_tumor_susceptibility | 0.33824377 |
138 | MP0005376_homeostasis/metabolism_phenot | 0.33005817 |
139 | MP0002133_abnormal_respiratory_system | 0.32950757 |
140 | MP0005388_respiratory_system_phenotype | 0.32950757 |
141 | MP0001853_heart_inflammation | 0.31557185 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Sudden death (HP:0001699) | 6.33894733 |
2 | Exercise-induced myalgia (HP:0003738) | 6.19226542 |
3 | Calf muscle hypertrophy (HP:0008981) | 5.88415568 |
4 | Exercise-induced muscle cramps (HP:0003710) | 5.84536908 |
5 | Ventricular tachycardia (HP:0004756) | 5.79096709 |
6 | Muscle fiber splitting (HP:0003555) | 5.67456131 |
7 | Muscle hypertrophy of the lower extremities (HP:0008968) | 5.58273231 |
8 | Myoglobinuria (HP:0002913) | 5.38035398 |
9 | Hyporeflexia of lower limbs (HP:0002600) | 5.22963917 |
10 | Lipoatrophy (HP:0100578) | 4.80524784 |
11 | Difficulty running (HP:0009046) | 4.74933307 |
12 | Atrial fibrillation (HP:0005110) | 4.72954931 |
13 | Myopathic facies (HP:0002058) | 4.67818251 |
14 | Abnormality of the calf musculature (HP:0001430) | 4.65897103 |
15 | Increased connective tissue (HP:0009025) | 4.42921660 |
16 | Primary atrial arrhythmia (HP:0001692) | 4.36961695 |
17 | Rhabdomyolysis (HP:0003201) | 4.18200716 |
18 | Supraventricular tachycardia (HP:0004755) | 4.18111986 |
19 | Right ventricular cardiomyopathy (HP:0011663) | 4.16569222 |
20 | Supraventricular arrhythmia (HP:0005115) | 4.14223612 |
21 | Bundle branch block (HP:0011710) | 3.92385540 |
22 | Ulnar deviation of the wrist (HP:0003049) | 3.72669146 |
23 | Dilated cardiomyopathy (HP:0001644) | 3.71666047 |
24 | Abnormality of the left ventricular outflow tract (HP:0011103) | 3.67435005 |
25 | Subaortic stenosis (HP:0001682) | 3.67435005 |
26 | EMG: myopathic abnormalities (HP:0003458) | 3.66055455 |
27 | Asymmetric septal hypertrophy (HP:0001670) | 3.65638316 |
28 | Palpitations (HP:0001962) | 3.54012594 |
29 | Type 1 muscle fiber predominance (HP:0003803) | 3.46141730 |
30 | Syncope (HP:0001279) | 3.42455321 |
31 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 3.41654264 |
32 | Myotonia (HP:0002486) | 3.41267306 |
33 | Absent phalangeal crease (HP:0006109) | 3.36190138 |
34 | Muscle fiber inclusion bodies (HP:0100299) | 3.31113604 |
35 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 3.25860769 |
36 | Frequent falls (HP:0002359) | 3.24577226 |
37 | Calcaneovalgus deformity (HP:0001848) | 3.23937451 |
38 | Prolonged QT interval (HP:0001657) | 3.20159083 |
39 | Heart block (HP:0012722) | 3.15203508 |
40 | Increased variability in muscle fiber diameter (HP:0003557) | 3.10548085 |
41 | Muscle stiffness (HP:0003552) | 3.08841496 |
42 | Difficulty climbing stairs (HP:0003551) | 3.06129131 |
43 | Abnormal atrioventricular conduction (HP:0005150) | 2.99905304 |
44 | Ventricular arrhythmia (HP:0004308) | 2.94600444 |
45 | Deformed tarsal bones (HP:0008119) | 2.89213694 |
46 | Atrioventricular block (HP:0001678) | 2.88501177 |
47 | Facial diplegia (HP:0001349) | 2.86942331 |
48 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.86504029 |
49 | Hypoplastic ischia (HP:0003175) | 2.85861072 |
50 | Malignant hyperthermia (HP:0002047) | 2.85797075 |
51 | Abnormal finger flexion creases (HP:0006143) | 2.84782381 |
52 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.79276963 |
53 | Nemaline bodies (HP:0003798) | 2.73202770 |
54 | Neck muscle weakness (HP:0000467) | 2.60362884 |
55 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.59845175 |
56 | Oligomenorrhea (HP:0000876) | 2.59157385 |
57 | Hypoglycemic coma (HP:0001325) | 2.58630288 |
58 | Abnormality of the ischium (HP:0003174) | 2.52492668 |
59 | Hyperkalemia (HP:0002153) | 2.52432330 |
60 | Distal lower limb muscle weakness (HP:0009053) | 2.48512036 |
61 | Ketoacidosis (HP:0001993) | 2.47913578 |
62 | Ventricular fibrillation (HP:0001663) | 2.41121466 |
63 | Areflexia of lower limbs (HP:0002522) | 2.40238621 |
64 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.39483231 |
65 | Increased muscle lipid content (HP:0009058) | 2.36312179 |
66 | Left ventricular hypertrophy (HP:0001712) | 2.35508799 |
67 | Broad metatarsal (HP:0001783) | 2.31723496 |
68 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.31451800 |
69 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.30718322 |
70 | Absent/shortened dynein arms (HP:0200106) | 2.30718322 |
71 | Hepatic necrosis (HP:0002605) | 2.29473488 |
72 | Impaired proprioception (HP:0010831) | 2.28633283 |
73 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.28587470 |
74 | Dicarboxylic aciduria (HP:0003215) | 2.28171652 |
75 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.28171652 |
76 | Muscular dystrophy (HP:0003560) | 2.27763081 |
77 | Weak cry (HP:0001612) | 2.26002725 |
78 | Abnormal EKG (HP:0003115) | 2.25037613 |
79 | Distal arthrogryposis (HP:0005684) | 2.23662267 |
80 | Acute necrotizing encephalopathy (HP:0006965) | 2.22724104 |
81 | Abnormality of the neuromuscular junction (HP:0003398) | 2.22612671 |
82 | Fatigable weakness (HP:0003473) | 2.22612671 |
83 | Fetal akinesia sequence (HP:0001989) | 2.22367042 |
84 | Acanthosis nigricans (HP:0000956) | 2.21163792 |
85 | Foot dorsiflexor weakness (HP:0009027) | 2.19113252 |
86 | Testicular atrophy (HP:0000029) | 2.19012989 |
87 | Abnormality of the foot musculature (HP:0001436) | 2.11755679 |
88 | Rimmed vacuoles (HP:0003805) | 2.10364232 |
89 | Bulbar palsy (HP:0001283) | 2.09625994 |
90 | Hyperglycinuria (HP:0003108) | 2.08833203 |
91 | Gowers sign (HP:0003391) | 2.07006829 |
92 | Spinal rigidity (HP:0003306) | 2.06180090 |
93 | Scapular winging (HP:0003691) | 2.05192691 |
94 | Palmoplantar keratoderma (HP:0000982) | 2.03948737 |
95 | Bone cyst (HP:0012062) | 2.03473770 |
96 | Round ear (HP:0100830) | 1.99775364 |
97 | Acute encephalopathy (HP:0006846) | 1.99242513 |
98 | Toxemia of pregnancy (HP:0100603) | 1.99173034 |
99 | Proximal amyotrophy (HP:0007126) | 1.98109330 |
100 | Abnormality of the nasal mucosa (HP:0000433) | 1.97630185 |
101 | Ketosis (HP:0001946) | 1.96581074 |
102 | Generalized muscle weakness (HP:0003324) | 1.95922113 |
103 | Conjunctival hamartoma (HP:0100780) | 1.95442054 |
104 | Hypoalphalipoproteinemia (HP:0003233) | 1.94437021 |
105 | Progressive macrocephaly (HP:0004481) | 1.94420225 |
106 | Hip contracture (HP:0003273) | 1.93392681 |
107 | EMG: neuropathic changes (HP:0003445) | 1.91618654 |
108 | Limb-girdle muscle atrophy (HP:0003797) | 1.89207380 |
109 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.88899412 |
110 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.88499747 |
111 | Abnormality of alanine metabolism (HP:0010916) | 1.88499747 |
112 | Hyperalaninemia (HP:0003348) | 1.88499747 |
113 | Abnormality of the shoulder girdle musculature (HP:0001435) | 1.88478198 |
114 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.87422343 |
115 | Progressive muscle weakness (HP:0003323) | 1.87357565 |
116 | Cerebral edema (HP:0002181) | 1.85497397 |
117 | Increased intramyocellular lipid droplets (HP:0012240) | 1.84888428 |
118 | Large for gestational age (HP:0001520) | 1.83678051 |
119 | Exercise intolerance (HP:0003546) | 1.83622869 |
120 | Ulnar claw (HP:0001178) | 1.82852992 |
121 | Type 2 muscle fiber atrophy (HP:0003554) | 1.82749879 |
122 | Waddling gait (HP:0002515) | 1.79735580 |
123 | Respiratory insufficiency due to muscle weakness (HP:0002747) | 1.71609351 |
124 | Nonprogressive disorder (HP:0003680) | 1.70849662 |
125 | Ragged-red muscle fibers (HP:0003200) | 1.68089089 |
126 | Shoulder girdle muscle weakness (HP:0003547) | 1.65290734 |
127 | Slender build (HP:0001533) | 1.61924725 |
128 | Hepatocellular necrosis (HP:0001404) | 1.61361582 |
129 | Abnormality of the calcaneus (HP:0008364) | 1.61245606 |
130 | Mitochondrial inheritance (HP:0001427) | 1.60582582 |
131 | Distal lower limb amyotrophy (HP:0008944) | 1.60508013 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PDK3 | 5.43039589 |
2 | PDK4 | 5.43039589 |
3 | TTN | 5.20774691 |
4 | OBSCN | 3.87921939 |
5 | PHKG1 | 3.70289857 |
6 | PHKG2 | 3.70289857 |
7 | PDK2 | 3.66536533 |
8 | MYLK | 3.54301030 |
9 | LMTK2 | 3.33096045 |
10 | TRIB3 | 2.67607455 |
11 | DMPK | 2.29670028 |
12 | BCKDK | 2.27579938 |
13 | TIE1 | 2.09634381 |
14 | FRK | 1.96081153 |
15 | PIK3CA | 1.88413733 |
16 | PINK1 | 1.77252228 |
17 | PKN2 | 1.53225436 |
18 | CAMK1D | 1.46940045 |
19 | MARK1 | 1.45124382 |
20 | MUSK | 1.36966106 |
21 | STK24 | 1.30711159 |
22 | PTK2B | 1.26825920 |
23 | WNK4 | 1.26038464 |
24 | CAMK1G | 1.22445036 |
25 | PRKD3 | 1.22069616 |
26 | PRKAA2 | 1.12952781 |
27 | RIPK1 | 1.10250574 |
28 | BMPR1B | 1.03518786 |
29 | STK39 | 1.02983239 |
30 | NEK1 | 1.02593016 |
31 | CCNB1 | 1.01747322 |
32 | SIK1 | 0.98401082 |
33 | MAP2K4 | 0.95151794 |
34 | PDGFRA | 0.94984055 |
35 | PRKD1 | 0.92087926 |
36 | MAPK13 | 0.91777958 |
37 | ILK | 0.88787145 |
38 | PRKAA1 | 0.87902141 |
39 | MAP4K2 | 0.87258988 |
40 | MAP2K3 | 0.86955873 |
41 | GRK7 | 0.86865583 |
42 | STK38L | 0.84462814 |
43 | TGFBR2 | 0.84309787 |
44 | PAK3 | 0.83163009 |
45 | ERBB3 | 0.82622336 |
46 | MAP2K6 | 0.81746618 |
47 | MAPK12 | 0.80723030 |
48 | WNK3 | 0.80617568 |
49 | INSRR | 0.80601502 |
50 | GRK1 | 0.79678103 |
51 | DAPK2 | 0.77482315 |
52 | OXSR1 | 0.77244625 |
53 | NEK9 | 0.76693293 |
54 | ROCK1 | 0.76618265 |
55 | ICK | 0.75472431 |
56 | LIMK1 | 0.74910633 |
57 | PIK3CG | 0.73809738 |
58 | ADRBK2 | 0.73621568 |
59 | EPHB2 | 0.73490280 |
60 | TNIK | 0.71101604 |
61 | MAP3K3 | 0.70207194 |
62 | NLK | 0.67978962 |
63 | WNK1 | 0.66453605 |
64 | EPHB1 | 0.65382168 |
65 | CAMK2D | 0.64858066 |
66 | ZAK | 0.63718090 |
67 | MAPKAPK3 | 0.63662031 |
68 | MAP3K7 | 0.60967630 |
69 | MAP3K4 | 0.59388229 |
70 | STK38 | 0.58508767 |
71 | KDR | 0.57551920 |
72 | TRPM7 | 0.56665431 |
73 | CAMK2B | 0.51556973 |
74 | LATS1 | 0.50280020 |
75 | ACVR1B | 0.49696126 |
76 | FGFR3 | 0.49511084 |
77 | TAOK3 | 0.49086809 |
78 | SGK2 | 0.48843773 |
79 | PDK1 | 0.47350081 |
80 | JAK1 | 0.47030476 |
81 | MAPK7 | 0.46811311 |
82 | PDPK1 | 0.46704273 |
83 | NME1 | 0.46526299 |
84 | CDC42BPA | 0.46235773 |
85 | PKN1 | 0.45663284 |
86 | PAK2 | 0.45136728 |
87 | FER | 0.44265763 |
88 | DAPK3 | 0.43407536 |
89 | FGFR4 | 0.43338444 |
90 | PRKACG | 0.42507426 |
91 | CAMK1 | 0.42482580 |
92 | PNCK | 0.41686471 |
93 | MAP3K5 | 0.40351981 |
94 | ERN1 | 0.37814046 |
95 | PRKG2 | 0.37728404 |
96 | AKT2 | 0.37354960 |
97 | PLK2 | 0.37026651 |
98 | IRAK1 | 0.36064589 |
99 | PRKACB | 0.35160322 |
100 | STK11 | 0.34307160 |
101 | SGK1 | 0.33486442 |
102 | MAPK4 | 0.33359016 |
103 | MST1R | 0.32698528 |
104 | RET | 0.32693241 |
105 | MAPK11 | 0.32449417 |
106 | PDGFRB | 0.32149004 |
107 | CAMK4 | 0.31386251 |
108 | RPS6KA3 | 0.30999755 |
109 | MOS | 0.30930697 |
110 | PRKACA | 0.30769350 |
111 | STK4 | 0.29352439 |
112 | ADRBK1 | 0.29175764 |
113 | PRKCH | 0.28193484 |
114 | PTK6 | 0.26636533 |
115 | CAMK2G | 0.26020643 |
116 | PRKG1 | 0.25890758 |
117 | TBK1 | 0.25809675 |
118 | SGK3 | 0.25806174 |
119 | MAPKAPK5 | 0.25046514 |
120 | STK3 | 0.24952208 |
121 | MTOR | 0.24873194 |
122 | MAP2K1 | 0.24857600 |
123 | ROCK2 | 0.24252224 |
124 | EPHA4 | 0.24217176 |
125 | CAMK2A | 0.24148220 |
126 | DYRK1B | 0.23816824 |
127 | CDK19 | 0.23197367 |
128 | RPS6KL1 | 0.22932416 |
129 | RPS6KC1 | 0.22932416 |
130 | PRKCE | 0.22872316 |
131 | TESK1 | 0.22384013 |
132 | SGK494 | 0.22338701 |
133 | SGK223 | 0.22338701 |
134 | DDR2 | 0.21984338 |
135 | FLT3 | 0.21953713 |
136 | MARK3 | 0.21792403 |
137 | GSK3A | 0.20711899 |
138 | CASK | 0.20080981 |
139 | PAK6 | 0.20033850 |
140 | IRAK2 | 0.19948839 |
141 | RPS6KA6 | 0.18783338 |
142 | TNK2 | 0.18446119 |
143 | RPS6KA1 | 0.18388560 |
144 | RPS6KB1 | 0.18060370 |
145 | UHMK1 | 0.17842906 |
146 | JAK2 | 0.16840735 |
147 | NTRK3 | 0.16333256 |
148 | EPHA3 | 0.16301912 |
149 | PRKCG | 0.14653429 |
150 | PRKCA | 0.13901060 |
151 | EEF2K | 0.13640199 |
152 | MAPK10 | 0.13409225 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 5.39632455 |
2 | Propanoate metabolism_Homo sapiens_hsa00640 | 4.30672597 |
3 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 3.41357039 |
4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.20207380 |
5 | Fatty acid degradation_Homo sapiens_hsa00071 | 3.06231024 |
6 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.88848972 |
7 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 2.87534616 |
8 | Fatty acid metabolism_Homo sapiens_hsa01212 | 2.72445459 |
9 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.63305936 |
10 | PPAR signaling pathway_Homo sapiens_hsa03320 | 2.53551373 |
11 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.52116448 |
12 | Carbon metabolism_Homo sapiens_hsa01200 | 2.38050623 |
13 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.17012469 |
14 | Parkinsons disease_Homo sapiens_hsa05012 | 2.12495228 |
15 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.09891746 |
16 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.04142965 |
17 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.88349036 |
18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.81788900 |
19 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.76266413 |
20 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.69671230 |
21 | Alzheimers disease_Homo sapiens_hsa05010 | 1.68078693 |
22 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.65739039 |
23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.60386579 |
24 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.58869701 |
25 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.50141135 |
26 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.47202860 |
27 | Viral myocarditis_Homo sapiens_hsa05416 | 1.37851599 |
28 | Phototransduction_Homo sapiens_hsa04744 | 1.30947776 |
29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.30931298 |
30 | Insulin resistance_Homo sapiens_hsa04931 | 1.29060056 |
31 | AMPK signaling pathway_Homo sapiens_hsa04152 | 1.25067924 |
32 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.23641674 |
33 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.22992753 |
34 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.21416245 |
35 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.13797808 |
36 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.10833331 |
37 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.09969866 |
38 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.06197311 |
39 | Focal adhesion_Homo sapiens_hsa04510 | 1.04001469 |
40 | Circadian entrainment_Homo sapiens_hsa04713 | 1.02122113 |
41 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.01918664 |
42 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.95280035 |
43 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.93661549 |
44 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.92016292 |
45 | Olfactory transduction_Homo sapiens_hsa04740 | 0.86985482 |
46 | Renin secretion_Homo sapiens_hsa04924 | 0.86259690 |
47 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.84960799 |
48 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.79071068 |
49 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.78135166 |
50 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.77191429 |
51 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.76919850 |
52 | Peroxisome_Homo sapiens_hsa04146 | 0.74221546 |
53 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.73239620 |
54 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.69829198 |
55 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.67806721 |
56 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.66523989 |
57 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.65110448 |
58 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.65098215 |
59 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.62995586 |
60 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.62402507 |
61 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.60407339 |
62 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.58738707 |
63 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.58331380 |
64 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.57177195 |
65 | Histidine metabolism_Homo sapiens_hsa00340 | 0.55965820 |
66 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.55511158 |
67 | Tight junction_Homo sapiens_hsa04530 | 0.54765757 |
68 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.54584133 |
69 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.54469710 |
70 | GABAergic synapse_Homo sapiens_hsa04727 | 0.54189257 |
71 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.52974571 |
72 | Lysine degradation_Homo sapiens_hsa00310 | 0.50351524 |
73 | RNA degradation_Homo sapiens_hsa03018 | 0.50124050 |
74 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.50018617 |
75 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.49485838 |
76 | Purine metabolism_Homo sapiens_hsa00230 | 0.49296767 |
77 | Morphine addiction_Homo sapiens_hsa05032 | 0.49129392 |
78 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.48827094 |
79 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.48644772 |
80 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.48516092 |
81 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.47664255 |
82 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.47509838 |
83 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.47407993 |
84 | Amoebiasis_Homo sapiens_hsa05146 | 0.46970810 |
85 | Nicotine addiction_Homo sapiens_hsa05033 | 0.46618310 |
86 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.44780810 |
87 | ABC transporters_Homo sapiens_hsa02010 | 0.44360013 |
88 | Taste transduction_Homo sapiens_hsa04742 | 0.43921760 |
89 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.43474999 |
90 | Long-term depression_Homo sapiens_hsa04730 | 0.40133091 |
91 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.37807833 |
92 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.37492889 |
93 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.36670458 |
94 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.36636052 |
95 | Adherens junction_Homo sapiens_hsa04520 | 0.36623018 |
96 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.36578691 |
97 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.36137718 |
98 | Long-term potentiation_Homo sapiens_hsa04720 | 0.35884496 |
99 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.35824129 |
100 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.35669258 |
101 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.34980913 |
102 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.34396714 |
103 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.34115622 |
104 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.33695751 |
105 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.33214473 |
106 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.33203952 |
107 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.33117801 |
108 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.33074140 |
109 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.31710462 |
110 | Galactose metabolism_Homo sapiens_hsa00052 | 0.31663185 |
111 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.30571911 |
112 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.28237391 |
113 | Circadian rhythm_Homo sapiens_hsa04710 | 0.27609124 |
114 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.26060525 |
115 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.25946311 |
116 | Basal transcription factors_Homo sapiens_hsa03022 | 0.25759290 |
117 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.25101328 |
118 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.24111077 |
119 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.24043404 |
120 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.22366597 |
121 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.21836269 |
122 | Platelet activation_Homo sapiens_hsa04611 | 0.21205403 |
123 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.19454110 |
124 | Metabolic pathways_Homo sapiens_hsa01100 | 0.19349288 |
125 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.15951871 |
126 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.13393687 |
127 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.10512597 |
128 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.09010697 |
129 | Bile secretion_Homo sapiens_hsa04976 | 0.08481099 |
130 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.06493255 |
131 | Salivary secretion_Homo sapiens_hsa04970 | 0.05873194 |
132 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.05639565 |
133 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.05519604 |
134 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.05465071 |
135 | Insulin secretion_Homo sapiens_hsa04911 | 0.05280047 |