ASB11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)8.42961018
2muscle filament sliding (GO:0030049)7.89350794
3actin-myosin filament sliding (GO:0033275)7.89350794
4regulation of skeletal muscle contraction (GO:0014819)7.53380150
5positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)7.37687829
6cardiac myofibril assembly (GO:0055003)7.30923773
7myofibril assembly (GO:0030239)7.29864258
8negative regulation of potassium ion transmembrane transporter activity (GO:1901017)7.10447223
9sarcoplasmic reticulum calcium ion transport (GO:0070296)7.00048603
10regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)6.86219331
11actin-mediated cell contraction (GO:0070252)6.50337236
12tricarboxylic acid cycle (GO:0006099)6.31577117
13negative regulation of potassium ion transmembrane transport (GO:1901380)6.24851183
14regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO6.02244500
15cardiac muscle contraction (GO:0060048)6.01681965
16plasma membrane repair (GO:0001778)6.01201180
17regulation of relaxation of muscle (GO:1901077)5.96260402
18regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.93579211
19regulation of cell communication by electrical coupling (GO:0010649)5.80138547
20regulation of actin filament-based movement (GO:1903115)5.71495947
21regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.71486290
22carnitine shuttle (GO:0006853)5.64247756
23striated muscle contraction (GO:0006941)5.59299360
24regulation of acyl-CoA biosynthetic process (GO:0050812)5.46672538
25skeletal muscle contraction (GO:0003009)5.43623166
26actomyosin structure organization (GO:0031032)5.40900191
27cardiac muscle cell development (GO:0055013)5.34070118
28regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)5.32919567
29regulation of sarcomere organization (GO:0060297)5.08999926
30cardiac muscle hypertrophy (GO:0003300)5.04279680
31response to stimulus involved in regulation of muscle adaptation (GO:0014874)5.03961051
32cardiac cell development (GO:0055006)4.98087180
33creatine metabolic process (GO:0006600)4.97484457
34regulation of cofactor metabolic process (GO:0051193)4.95818112
35regulation of coenzyme metabolic process (GO:0051196)4.95818112
36regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.94190166
37striated muscle hypertrophy (GO:0014897)4.87332561
38skeletal muscle adaptation (GO:0043501)4.86906336
39fatty acid transmembrane transport (GO:1902001)4.86464031
40actin filament-based movement (GO:0030048)4.82642399
41regulation of striated muscle contraction (GO:0006942)4.68436079
42ventricular cardiac muscle cell action potential (GO:0086005)4.68009763
43heart process (GO:0003015)4.64127220
44heart contraction (GO:0060047)4.64127220
45cardiac muscle tissue morphogenesis (GO:0055008)4.51596971
46skeletal muscle fiber development (GO:0048741)4.46471867
47regulation of calcineurin-NFAT signaling cascade (GO:0070884)4.42686897
48adult heart development (GO:0007512)4.41813333
49muscle fiber development (GO:0048747)4.41555846
50myotube cell development (GO:0014904)4.36989549
51regulation of membrane repolarization (GO:0060306)4.33017790
52bundle of His cell to Purkinje myocyte communication (GO:0086069)4.30375065
53muscle hypertrophy (GO:0014896)4.29956054
54mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.22143656
55carnitine transmembrane transport (GO:1902603)4.19103468
56heart trabecula formation (GO:0060347)4.16498891
57muscle tissue morphogenesis (GO:0060415)4.14057676
58NADH metabolic process (GO:0006734)4.13431745
59striated muscle adaptation (GO:0014888)4.10882760
60muscle contraction (GO:0006936)4.04468055
61regulation of sulfur metabolic process (GO:0042762)4.03347084
62positive regulation of calcium ion transmembrane transporter activity (GO:1901021)4.02366257
63ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.93992551
64cardiac muscle hypertrophy in response to stress (GO:0014898)3.92569959
65muscle hypertrophy in response to stress (GO:0003299)3.92569959
66cardiac muscle adaptation (GO:0014887)3.92569959
67pyrimidine ribonucleoside catabolic process (GO:0046133)3.91305879
68membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.91097653
692-oxoglutarate metabolic process (GO:0006103)3.90239350
70respiratory electron transport chain (GO:0022904)3.89729212
71response to inactivity (GO:0014854)3.87440789
72glycogen catabolic process (GO:0005980)3.87201711
73glucan biosynthetic process (GO:0009250)3.83079757
74amino-acid betaine transport (GO:0015838)3.82772494
75carnitine transport (GO:0015879)3.82772494
76skeletal muscle tissue development (GO:0007519)3.82663461
77electron transport chain (GO:0022900)3.79323641
78muscle system process (GO:0003012)3.78326708
79cell communication involved in cardiac conduction (GO:0086065)3.77902147
80mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.76701603
81negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.74945158
82negative regulation of calcium ion transmembrane transport (GO:1903170)3.74945158
83striated muscle atrophy (GO:0014891)3.73507751
84cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.72961470
85regulation of calcium ion transmembrane transport (GO:1903169)3.72037779
86regulation of calcium ion transmembrane transporter activity (GO:1901019)3.72037779
87oxidative phosphorylation (GO:0006119)3.71451680
88regulation of cardiac muscle cell contraction (GO:0086004)3.67807397
89regulation of sequestering of triglyceride (GO:0010889)3.65323321
90response to muscle activity (GO:0014850)3.64695970
91regulation of cardiac muscle contraction (GO:0055117)3.62816761
92regulation of the force of heart contraction (GO:0002026)3.61619633
93glucan catabolic process (GO:0009251)3.61242017
94muscle atrophy (GO:0014889)3.59749254
95positive regulation of cation channel activity (GO:2001259)3.59544742
96relaxation of cardiac muscle (GO:0055119)3.57269548
97striated muscle cell development (GO:0055002)3.56796080
98cardiac muscle cell action potential (GO:0086001)3.55920832
99muscle cell cellular homeostasis (GO:0046716)3.55672737
100cardiac muscle cell action potential involved in contraction (GO:0086002)3.55556817
101response to caffeine (GO:0031000)3.54333426
102regulation of ATPase activity (GO:0043462)3.53954125
103regulation of ATP catabolic process (GO:1903289)3.53954125
104negative regulation of potassium ion transport (GO:0043267)3.50860583
105energy coupled proton transport, down electrochemical gradient (GO:0015985)3.50725120
106ATP synthesis coupled proton transport (GO:0015986)3.50725120
107negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.50422679
108muscle adaptation (GO:0043500)3.47447110
109cytidine metabolic process (GO:0046087)3.47056709
110cytidine catabolic process (GO:0006216)3.47056709
111cytidine deamination (GO:0009972)3.47056709
112succinate metabolic process (GO:0006105)3.45034736
113positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.44169674
114ubiquinone biosynthetic process (GO:0006744)3.43423191
115regulation of heart rate (GO:0002027)3.40533621
116skeletal muscle tissue regeneration (GO:0043403)3.39605716
117cellular polysaccharide catabolic process (GO:0044247)3.39539778
118glycogen biosynthetic process (GO:0005978)3.36347361
119polysaccharide catabolic process (GO:0000272)3.27973738
120regulation of muscle system process (GO:0090257)3.23750556
121muscle structure development (GO:0061061)3.21477292
122regulation of muscle contraction (GO:0006937)3.19782759
123muscle organ development (GO:0007517)3.17033381
124glycogen metabolic process (GO:0005977)3.11556363
125relaxation of muscle (GO:0090075)3.10029588
126ubiquinone metabolic process (GO:0006743)3.09220303
127muscle cell development (GO:0055001)3.08876987

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.83795435
2ESRRB_18555785_ChIP-Seq_MESCs_Mouse4.22970646
3EP300_21415370_ChIP-Seq_HL-1_Mouse4.16569311
4TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.79473763
5TBX20_22080862_ChIP-Seq_HEART_Mouse3.61336834
6TBX20_22328084_ChIP-Seq_HEART_Mouse3.61336834
7BP1_19119308_ChIP-ChIP_Hs578T_Human3.22740234
8EZH2_22144423_ChIP-Seq_EOC_Human3.00446753
9ESR1_20079471_ChIP-ChIP_T-47D_Human2.93379054
10MEF2A_21415370_ChIP-Seq_HL-1_Mouse2.66699194
11GATA1_22025678_ChIP-Seq_K562_Human2.61127376
12PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.49730735
13RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.46205108
14IGF1R_20145208_ChIP-Seq_DFB_Human2.44565876
15ZNF263_19887448_ChIP-Seq_K562_Human2.43410404
16CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.31699273
17CDX2_19796622_ChIP-Seq_MESCs_Mouse2.22021129
18RARG_19884340_ChIP-ChIP_MEFs_Mouse2.18986584
19GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.14924744
20GATA4_21415370_ChIP-Seq_HL-1_Mouse2.05135291
21FLI1_27457419_Chip-Seq_LIVER_Mouse1.96376095
22POU3F2_20337985_ChIP-ChIP_501MEL_Human1.94930346
23ZFP57_27257070_Chip-Seq_ESCs_Mouse1.93665826
24PCGF2_27294783_Chip-Seq_ESCs_Mouse1.81844277
25NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.77599895
26THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.77494946
27EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.68893532
28ER_23166858_ChIP-Seq_MCF-7_Human1.64856618
29SUZ12_27294783_Chip-Seq_NPCs_Mouse1.63082080
30EZH2_27294783_Chip-Seq_NPCs_Mouse1.57552178
31PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.53969347
32BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.50899331
33NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.47789876
34TAF15_26573619_Chip-Seq_HEK293_Human1.47766662
35ZNF274_21170338_ChIP-Seq_K562_Hela1.45079326
36CBX2_27304074_Chip-Seq_ESCs_Mouse1.44738158
37ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.41638045
38FUS_26573619_Chip-Seq_HEK293_Human1.41486158
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.41060257
40HTT_18923047_ChIP-ChIP_STHdh_Human1.39791115
41DROSHA_22980978_ChIP-Seq_HELA_Human1.39135586
42CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.38914610
43BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.38835632
44PCGF2_27294783_Chip-Seq_NPCs_Mouse1.38289472
45CRX_20693478_ChIP-Seq_RETINA_Mouse1.33804412
46ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.32399212
47CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.32167754
48TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.32111733
49EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.27666227
50CLOCK_20551151_ChIP-Seq_293T_Human1.26954101
51NFE2_27457419_Chip-Seq_LIVER_Mouse1.26823191
52NR3C1_21868756_ChIP-Seq_MCF10A_Human1.26789432
53CTBP2_25329375_ChIP-Seq_LNCAP_Human1.25801528
54SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.25561479
55SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.25152384
56CTCF_27219007_Chip-Seq_Bcells_Human1.24793861
57TCF4_23295773_ChIP-Seq_U87_Human1.24199305
58NANOG_19829295_ChIP-Seq_ESCs_Human1.23839811
59SOX2_19829295_ChIP-Seq_ESCs_Human1.23839811
60FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.23013704
61ESR2_21235772_ChIP-Seq_MCF-7_Human1.21562160
62NR3C1_23031785_ChIP-Seq_PC12_Mouse1.21081739
63EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.17926502
64OCT4_21477851_ChIP-Seq_ESCs_Mouse1.17394758
65CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.16782396
66TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.16289638
67UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15916537
68ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.15888161
69STAT3_23295773_ChIP-Seq_U87_Human1.15567093
70TOP2B_26459242_ChIP-Seq_MCF-7_Human1.15185564
71P300_19829295_ChIP-Seq_ESCs_Human1.15144759
72GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14621475
73MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14209008
74SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.12581441
75KLF5_20875108_ChIP-Seq_MESCs_Mouse1.12414166
76PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.10936285
77E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.10886239
78AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.10083500
79SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.09234561
80RARB_27405468_Chip-Seq_BRAIN_Mouse1.07888604
81SOX2_21211035_ChIP-Seq_LN229_Gbm1.07703538
82TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.07648521
83PIAS1_25552417_ChIP-Seq_VCAP_Human1.07590053
84SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.06523756
85TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.05852827
86FOXH1_21741376_ChIP-Seq_ESCs_Human1.04395023
87FLI1_21867929_ChIP-Seq_TH2_Mouse1.04349871
88LXR_22158963_ChIP-Seq_LIVER_Mouse1.02392543
89SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02283835
90PPARA_22158963_ChIP-Seq_LIVER_Mouse1.01379661
91SMAD3_21741376_ChIP-Seq_EPCs_Human1.01154977
92PHF8_20622853_ChIP-Seq_HELA_Human1.00860359
93SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.00571526
94P53_22387025_ChIP-Seq_ESCs_Mouse1.00402086
95AR_25329375_ChIP-Seq_VCAP_Human0.99902448
96GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.98629128
97AR_21572438_ChIP-Seq_LNCaP_Human0.98454028
98SMAD4_21741376_ChIP-Seq_EPCs_Human0.98277596
99VDR_22108803_ChIP-Seq_LS180_Human0.97953477
100OCT4_20526341_ChIP-Seq_ESCs_Human0.97001889
101CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.96514147
102NFYB_21822215_ChIP-Seq_K562_Human0.96210896
103CTBP1_25329375_ChIP-Seq_LNCAP_Human0.96104852
104TBL1_22424771_ChIP-Seq_293T_Human0.95757103
105RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.95221751
106MTF2_20144788_ChIP-Seq_MESCs_Mouse0.94693039
107OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94572120
108NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.94363148
109NRF2_20460467_ChIP-Seq_MEFs_Mouse0.94363148
110E2F1_18555785_Chip-Seq_ESCs_Mouse0.93368256
111LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.93028506
112EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.91352787
113NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.91350050
114ETV1_20927104_ChIP-Seq_GIST48_Human0.91319112
115SMAD3_21741376_ChIP-Seq_HESCs_Human0.90394008
116GATA6_21074721_ChIP-Seq_CACO-2_Human0.89988114
117TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.89556362
118EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.89033701
119STAT3_18555785_Chip-Seq_ESCs_Mouse0.89025570
120TP63_22573176_ChIP-Seq_HFKS_Human0.89021021
121SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.88864753
122PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.88856394
123ESR1_21235772_ChIP-Seq_MCF-7_Human0.87822439
124AUTS2_25519132_ChIP-Seq_293T-REX_Human0.87310695
125EZH2_27294783_Chip-Seq_ESCs_Mouse0.86711352
126PPAR_26484153_Chip-Seq_NCI-H1993_Human0.84673767
127SMAD4_21741376_ChIP-Seq_HESCs_Human0.84268153
128TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.83452546
129GATA2_21666600_ChIP-Seq_HMVEC_Human0.83059599
130BCAT_22108803_ChIP-Seq_LS180_Human0.82032708
131RNF2_18974828_ChIP-Seq_MESCs_Mouse0.80984673
132EZH2_18974828_ChIP-Seq_MESCs_Mouse0.80984673
133EZH2_27304074_Chip-Seq_ESCs_Mouse0.80600749
134CTCF_21964334_ChIP-Seq_BJAB-B_Human0.79016467
135CJUN_26792858_Chip-Seq_BT549_Human0.78793720
136CTNNB1_20460455_ChIP-Seq_HCT116_Human0.78229297
137FOXA2_19822575_ChIP-Seq_HepG2_Human0.78180451
138SMC3_22415368_ChIP-Seq_MEFs_Mouse0.77336078
139ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.76877904
140GATA1_19941826_ChIP-Seq_K562_Human0.76292813
141CBP_21632823_ChIP-Seq_H3396_Human0.75842584
142TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.75356330
143KDM2B_26808549_Chip-Seq_SUP-B15_Human0.74729595
144SMAD4_21799915_ChIP-Seq_A2780_Human0.74344691
145RXR_22158963_ChIP-Seq_LIVER_Mouse0.74103257
146GBX2_23144817_ChIP-Seq_PC3_Human0.73045839
147P68_20966046_ChIP-Seq_HELA_Human0.72728169
148SPI1_20517297_ChIP-Seq_HL60_Human0.71878823
149GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.71548634
150SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.70823584
151* DNAJC2_21179169_ChIP-ChIP_NT2_Human0.70615896
152P63_26484246_Chip-Seq_KERATINOCYTES_Human0.69764005
153CBP_20019798_ChIP-Seq_JUKART_Human0.69444924
154IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.69444924
155EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.69148243
156ATF3_27146783_Chip-Seq_COLON_Human0.68675119
157GATA2_19941826_ChIP-Seq_K562_Human0.68601541
158RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.68316122
159SOX9_24532713_ChIP-Seq_HFSC_Mouse0.68158932
160RUNX1_27514584_Chip-Seq_MCF-7_Human0.67907920
161MYC_27129775_Chip-Seq_CORNEA_Mouse0.67795456
162AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.67083235

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis6.69380439
2MP0003646_muscle_fatigue6.28253009
3MP0000751_myopathy5.40012929
4MP0004084_abnormal_cardiac_muscle4.67923201
5MP0000749_muscle_degeneration4.63724384
6MP0004036_abnormal_muscle_relaxation4.31642115
7MP0004215_abnormal_myocardial_fiber4.10272818
8MP0004145_abnormal_muscle_electrophysio4.02212995
9MP0005330_cardiomyopathy3.44595279
10MP0004087_abnormal_muscle_fiber3.21295829
11MP0004130_abnormal_muscle_cell3.18761691
12MP0002106_abnormal_muscle_physiology3.07061796
13MP0005620_abnormal_muscle_contractility2.91611609
14MP0000750_abnormal_muscle_regeneration2.88919826
15MP0002269_muscular_atrophy2.72409743
16MP0002972_abnormal_cardiac_muscle2.71799576
17MP0000747_muscle_weakness2.65181039
18MP0000759_abnormal_skeletal_muscle2.52336410
19MP0005369_muscle_phenotype2.50523633
20MP0003137_abnormal_impulse_conducting2.46156126
21MP0008775_abnormal_heart_ventricle2.42902007
22MP0004484_altered_response_of2.41241307
23MP0005385_cardiovascular_system_phenoty2.23457097
24MP0001544_abnormal_cardiovascular_syste2.23457097
25MP0010630_abnormal_cardiac_muscle2.20629482
26MP0006036_abnormal_mitochondrial_physio2.01835658
27MP0004233_abnormal_muscle_weight1.98447345
28MP0006138_congestive_heart_failure1.86016904
29MP0003221_abnormal_cardiomyocyte_apopto1.81293778
30MP0004085_abnormal_heartbeat1.76392348
31MP0002332_abnormal_exercise_endurance1.69555552
32MP0003828_pulmonary_edema1.65983864
33MP0005666_abnormal_adipose_tissue1.57929882
34MP0004510_myositis1.45805110
35MP0004185_abnormal_adipocyte_glucose1.38679171
36MP0002127_abnormal_cardiovascular_syste1.38339163
37MP0000372_irregular_coat_pigmentation1.29126939
38MP0003950_abnormal_plasma_membrane1.21060314
39MP0005670_abnormal_white_adipose1.18972189
40MP0006035_abnormal_mitochondrial_morpho1.13402591
41MP0002108_abnormal_muscle_morphology1.13241698
42MP0004043_abnormal_pH_regulation1.10652800
43MP0001661_extended_life_span1.10126484
44MP0005375_adipose_tissue_phenotype1.10117752
45MP0002234_abnormal_pharynx_morphology1.07120113
46MP0000343_altered_response_to1.02258410
47MP0000266_abnormal_heart_morphology0.95184471
48MP0003567_abnormal_fetal_cardiomyocyte0.92358526
49MP0005165_increased_susceptibility_to0.91575193
50MP0002638_abnormal_pupillary_reflex0.90494701
51MP0005266_abnormal_metabolism0.88563689
52MP0002971_abnormal_brown_adipose0.84844277
53MP0000733_abnormal_muscle_development0.83341547
54MP0000013_abnormal_adipose_tissue0.82060591
55MP0009780_abnormal_chondrocyte_physiolo0.80654623
56MP0000230_abnormal_systemic_arterial0.79983407
57MP0004147_increased_porphyrin_level0.78924116
58MP0002078_abnormal_glucose_homeostasis0.75195512
59MP0002909_abnormal_adrenal_gland0.75007329
60MP0004142_abnormal_muscle_tone0.73150256
61MP0000003_abnormal_adipose_tissue0.68677316
62MP0005645_abnormal_hypothalamus_physiol0.61230381
63MP0005535_abnormal_body_temperature0.59781814
64MP0005451_abnormal_body_composition0.59442985
65MP0002822_catalepsy0.58982052
66MP0008961_abnormal_basal_metabolism0.57312079
67MP0003806_abnormal_nucleotide_metabolis0.57199663
68MP0001984_abnormal_olfaction0.55706817
69MP0002876_abnormal_thyroid_physiology0.52622854
70MP0002128_abnormal_blood_circulation0.51995590
71MP0003279_aneurysm0.50096868
72MP0005334_abnormal_fat_pad0.48713269
73MP0006276_abnormal_autonomic_nervous0.47962646
74MP0003195_calcinosis0.47686586
75MP0005332_abnormal_amino_acid0.47265984
76MP0005319_abnormal_enzyme/_coenzyme0.45859651
77MP0010368_abnormal_lymphatic_system0.44809367
78MP0003045_fibrosis0.44448963
79MP0002272_abnormal_nervous_system0.44009684
80MP0004134_abnormal_chest_morphology0.43470703
81MP0001501_abnormal_sleep_pattern0.43348831
82MP0005187_abnormal_penis_morphology0.43149067
83MP0009745_abnormal_behavioral_response0.42811705
84MP0005083_abnormal_biliary_tract0.42638890
85MP0003136_yellow_coat_color0.41831446
86MP0009046_muscle_twitch0.39819959
87MP0005423_abnormal_somatic_nervous0.39648377
88MP0003705_abnormal_hypodermis_morpholog0.39207375
89MP0001879_abnormal_lymphatic_vessel0.36961324
90MP0002118_abnormal_lipid_homeostasis0.36678819
91MP0002067_abnormal_sensory_capabilities0.35804256
92MP0008569_lethality_at_weaning0.35386473
93MP0002734_abnormal_mechanical_nocicepti0.34045101
94MP0001986_abnormal_taste_sensitivity0.33743369
95MP0003879_abnormal_hair_cell0.33497954
96MP0005452_abnormal_adipose_tissue0.33331721
97MP0001486_abnormal_startle_reflex0.33127580
98MP0002877_abnormal_melanocyte_morpholog0.33015346
99MP0002693_abnormal_pancreas_physiology0.32988013
100MP0005171_absent_coat_pigmentation0.32780550
101MP0003656_abnormal_erythrocyte_physiolo0.32744512
102MP0005386_behavior/neurological_phenoty0.32674372
103MP0004924_abnormal_behavior0.32674372
104MP0005584_abnormal_enzyme/coenzyme_acti0.32669831
105MP0005253_abnormal_eye_physiology0.32423469
106MP0003566_abnormal_cell_adhesion0.31497253
107MP0000569_abnormal_digit_pigmentation0.30941334
108MP0005551_abnormal_eye_electrophysiolog0.30480340
109MP0003948_abnormal_gas_homeostasis0.29604399
110MP0001502_abnormal_circadian_rhythm0.29534599
111MP0005623_abnormal_meninges_morphology0.29219224
112MP0002066_abnormal_motor_capabilities/c0.28698188
113MP0004270_analgesia0.28098937
114MP0001440_abnormal_grooming_behavior0.26768591
115MP0000767_abnormal_smooth_muscle0.26652339
116MP0001765_abnormal_ion_homeostasis0.26618925
117MP0005275_abnormal_skin_tensile0.26561202
118MP0001485_abnormal_pinna_reflex0.25515491
119MP0002925_abnormal_cardiovascular_devel0.24039839
120MP0005448_abnormal_energy_balance0.22907426
121MP0001299_abnormal_eye_distance/0.22721295
122MP0003959_abnormal_lean_body0.22668339
123MP0009115_abnormal_fat_cell0.22373948
124MP0001727_abnormal_embryo_implantation0.21671646
125MP0005167_abnormal_blood-brain_barrier0.21663299
126MP0003953_abnormal_hormone_level0.20509262
127MP0002896_abnormal_bone_mineralization0.18736704
128MP0005376_homeostasis/metabolism_phenot0.18349110
129MP0005085_abnormal_gallbladder_physiolo0.17689795

Predicted human phenotypes

RankGene SetZ-score
1Exercise-induced myalgia (HP:0003738)7.49958786
2Exercise-induced muscle cramps (HP:0003710)7.07590723
3Calf muscle hypertrophy (HP:0008981)6.84135140
4Muscle hypertrophy of the lower extremities (HP:0008968)6.80579120
5Sudden death (HP:0001699)6.58374531
6Myoglobinuria (HP:0002913)5.76403381
7Muscle fiber splitting (HP:0003555)5.66699734
8Ventricular tachycardia (HP:0004756)5.56241788
9Abnormality of the calf musculature (HP:0001430)5.19999708
10Hyporeflexia of lower limbs (HP:0002600)5.17195935
11Muscle fiber inclusion bodies (HP:0100299)5.05491231
12Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.89088666
13Atrial fibrillation (HP:0005110)4.76433910
14Abnormality of the left ventricular outflow tract (HP:0011103)4.63754007
15Subaortic stenosis (HP:0001682)4.63754007
16Primary atrial arrhythmia (HP:0001692)4.45416276
17Rhabdomyolysis (HP:0003201)4.44758357
18EMG: myopathic abnormalities (HP:0003458)4.42089209
19Difficulty running (HP:0009046)4.36913780
20Lipoatrophy (HP:0100578)4.30720019
21Supraventricular tachycardia (HP:0004755)4.29298893
22Supraventricular arrhythmia (HP:0005115)4.18909839
23Nemaline bodies (HP:0003798)4.17195234
24Increased connective tissue (HP:0009025)4.12434623
25Myotonia (HP:0002486)3.94172553
26Type 1 muscle fiber predominance (HP:0003803)3.88639938
27Right ventricular cardiomyopathy (HP:0011663)3.87356043
28Asymmetric septal hypertrophy (HP:0001670)3.86439138
29Centrally nucleated skeletal muscle fibers (HP:0003687)3.86322635
30Bundle branch block (HP:0011710)3.84945869
31Syncope (HP:0001279)3.77761292
32Dilated cardiomyopathy (HP:0001644)3.73008568
33Palpitations (HP:0001962)3.67275112
34Muscle stiffness (HP:0003552)3.59907089
35Prolonged QT interval (HP:0001657)3.48294938
36Ventricular arrhythmia (HP:0004308)3.21562043
37Heart block (HP:0012722)3.17657605
38Myopathic facies (HP:0002058)3.12003531
39Difficulty climbing stairs (HP:0003551)3.11597853
40Distal arthrogryposis (HP:0005684)3.07945040
41Calcaneovalgus deformity (HP:0001848)3.04221368
42Abnormal atrioventricular conduction (HP:0005150)2.98690023
43Abnormal mitochondria in muscle tissue (HP:0008316)2.97770426
44Acute necrotizing encephalopathy (HP:0006965)2.92680608
45Increased variability in muscle fiber diameter (HP:0003557)2.91962362
46Areflexia of lower limbs (HP:0002522)2.91832700
47Distal lower limb muscle weakness (HP:0009053)2.90449134
48Abnormality of skeletal muscle fiber size (HP:0012084)2.87857401
49Atrioventricular block (HP:0001678)2.86770635
50Neck muscle weakness (HP:0000467)2.79707316
51Hepatic necrosis (HP:0002605)2.79176810
52Rimmed vacuoles (HP:0003805)2.74138315
53Deformed tarsal bones (HP:0008119)2.74030829
54Round ear (HP:0100830)2.73516167
55Ketoacidosis (HP:0001993)2.73118990
56Ventricular fibrillation (HP:0001663)2.70165526
57Abnormal finger flexion creases (HP:0006143)2.67725920
58Left ventricular hypertrophy (HP:0001712)2.62081271
59Malignant hyperthermia (HP:0002047)2.57911878
60Abnormal EKG (HP:0003115)2.55298360
61Acute encephalopathy (HP:0006846)2.53940410
62Ulnar deviation of the wrist (HP:0003049)2.51103600
63Hypoglycemic coma (HP:0001325)2.49298969
64Progressive macrocephaly (HP:0004481)2.46310409
65Hepatocellular necrosis (HP:0001404)2.42651148
66Limb-girdle muscle atrophy (HP:0003797)2.38565528
67Abnormality of alanine metabolism (HP:0010916)2.34713519
68Hyperalaninemia (HP:0003348)2.34713519
69Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.34713519
70Mitochondrial inheritance (HP:0001427)2.28284120
71Increased muscle lipid content (HP:0009058)2.28084532
72Exercise intolerance (HP:0003546)2.27899953
73Bulbar palsy (HP:0001283)2.27358966
74Distal lower limb amyotrophy (HP:0008944)2.26827006
75Hypoplastic ischia (HP:0003175)2.23167362
76Cerebral edema (HP:0002181)2.22032547
77Muscular dystrophy (HP:0003560)2.21410377
78Testicular atrophy (HP:0000029)2.21020438
79Fetal akinesia sequence (HP:0001989)2.20311459
80EMG: neuropathic changes (HP:0003445)2.18169759
81Abnormality of dicarboxylic acid metabolism (HP:0010995)2.17108810
82Dicarboxylic aciduria (HP:0003215)2.17108810
83Increased CSF lactate (HP:0002490)2.15359576
84Weak cry (HP:0001612)2.13370442
85Facial diplegia (HP:0001349)2.13143878
86Abnormality of fatty-acid metabolism (HP:0004359)2.11326470
87Palmoplantar keratoderma (HP:0000982)2.11100221
88Fatigable weakness (HP:0003473)2.09451423
89Abnormality of the neuromuscular junction (HP:0003398)2.09451423
90Slender build (HP:0001533)2.08731638
91Abnormality of the foot musculature (HP:0001436)2.06020490
92Proximal amyotrophy (HP:0007126)2.05417944
93Hyperinsulinemic hypoglycemia (HP:0000825)2.03739525
94Large for gestational age (HP:0001520)2.03239857
95Lactic acidosis (HP:0003128)2.02774379
96Increased intramyocellular lipid droplets (HP:0012240)2.01300009
97Conjunctival hamartoma (HP:0100780)2.01165568
98Gowers sign (HP:0003391)1.99349185
99Ketosis (HP:0001946)1.99301228
100Generalized muscle weakness (HP:0003324)1.96771375
101Abnormality of the ischium (HP:0003174)1.95329513
102Abnormality of the shoulder girdle musculature (HP:0001435)1.94249939
103Waddling gait (HP:0002515)1.93810249
104Insulin-resistant diabetes mellitus (HP:0000831)1.93162276
105Frequent falls (HP:0002359)1.92584094
106Hyperkalemia (HP:0002153)1.91738382
107Progressive muscle weakness (HP:0003323)1.89426220
108Mildly elevated creatine phosphokinase (HP:0008180)1.88906953
109Pheochromocytoma (HP:0002666)1.87250628
110Respiratory failure (HP:0002878)1.87008287
111Hip contracture (HP:0003273)1.85839825
112Hyperglycemia (HP:0003074)1.85562110
113Ragged-red muscle fibers (HP:0003200)1.85329184
114Scapular winging (HP:0003691)1.84083068
115Central scotoma (HP:0000603)1.83889887
116Respiratory insufficiency due to muscle weakness (HP:0002747)1.82093142
117Absent phalangeal crease (HP:0006109)1.81405203
118Foot dorsiflexor weakness (HP:0009027)1.80863115
119Type 2 muscle fiber atrophy (HP:0003554)1.65675755
120Abnormality of the musculature of the pelvis (HP:0001469)1.64539595
121Abnormality of the hip-girdle musculature (HP:0001445)1.64539595
122Oligomenorrhea (HP:0000876)1.64284049
123Spinal rigidity (HP:0003306)1.61769045
124Steppage gait (HP:0003376)1.60137331
125Nonprogressive disorder (HP:0003680)1.57199775
126Long clavicles (HP:0000890)1.56786576
127Shoulder girdle muscle weakness (HP:0003547)1.55345939
128Pelvic girdle muscle weakness (HP:0003749)1.49270266
129Lower limb amyotrophy (HP:0007210)1.47690470
130Limb-girdle muscle weakness (HP:0003325)1.45556201

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN6.56112618
2OBSCN5.37488131
3PHKG14.90966160
4PHKG24.90966160
5PDK33.46330020
6PDK43.46330020
7LMTK22.77582241
8BCKDK2.67052102
9DMPK2.61606018
10PINK12.45638809
11MYLK2.45330496
12TRIB32.43586707
13NEK12.38076134
14PKN22.35481595
15PIK3CA2.24578899
16PDK22.17049849
17NME12.03782359
18MUSK1.90051797
19STK241.62187354
20MARK11.53796236
21MAP3K71.48883615
22TIE11.48356424
23MAP2K31.43555111
24INSRR1.42643269
25FRK1.32514143
26GRK71.30294406
27MAPK121.28095266
28PIK3CG1.19623231
29CAMK2D1.06834584
30LIMK11.05499633
31PRKD10.97878887
32PRKAA10.97107261
33PRKAA20.95193169
34MAP2K40.88279636
35PAK30.84781708
36TRPM70.82861733
37CCNB10.82205591
38FLT30.79339155
39ILK0.78775438
40ZAK0.77130768
41RIPK10.76910793
42MAP4K20.75504057
43MAPKAPK30.74971652
44CDC42BPA0.73762077
45DAPK20.73119455
46MAPK130.72321318
47CAMK40.72310081
48BMPR1B0.71502524
49WNK40.65955628
50MAP3K30.63833209
51ROCK10.62884136
52MAP3K50.61817478
53PKN10.59932731
54CAMK2A0.57668749
55NEK90.56786265
56STK38L0.53891423
57MAP2K10.53644485
58TNIK0.52942267
59CAMK2G0.50082067
60MAP2K60.47942932
61ADRBK20.46246620
62PDGFRA0.45732803
63MAPK40.44965968
64CAMK10.44683767
65TAOK20.44436821
66STK380.43850897
67PDPK10.43297803
68PRKACB0.42960048
69PRKACA0.41753855
70OXSR10.41345873
71DAPK30.41294597
72MAP3K40.41104803
73WNK10.40809267
74STK40.39327161
75ACVR1B0.38986884
76PRKD30.38501502
77PDK10.37935351
78WNK30.36883397
79CASK0.36513823
80SGK10.36016223
81STK110.35856986
82SGK30.35813684
83RPS6KL10.34750165
84RPS6KC10.34750165
85PRKACG0.34530664
86EPHB10.34251153
87PTK2B0.34132705
88GRK10.33847522
89PRKCE0.33513139
90AKT20.30681411
91NLK0.28480053
92ROCK20.27894059
93MAP3K60.26801584
94PRKCH0.26552333
95RPS6KA60.26148632
96ADRBK10.25882197
97MAPK110.25719937
98MAPK70.25574407
99TGFBR20.25119160
100SGK20.24776303
101PTK60.24557395
102RET0.23873440
103PRKG10.23564879
104CAMKK20.23378686
105DYRK1B0.23280389
106RPS6KB10.22697384
107RPS6KA30.21282080
108MAP3K10.20665131
109TAOK10.20111530
110EEF2K0.18858001
111SIK10.18497249
112MOS0.18208460
113RPS6KA10.17883062
114SGK4940.17561809
115SGK2230.17561809
116LATS10.17052308
117TBK10.16779648
118PRKCQ0.16555302
119FER0.16068930
120CDK190.15377846
121MARK30.15342023
122PAK60.13764096
123ERBB30.13028421
124MAP2K70.12773371
125PRPF4B0.12619985
126JAK10.12203059
127EPHA30.12040105
128RPS6KA20.11996483
129PNCK0.11178214
130STK390.11174151
131KDR0.11028523
132MAPKAPK50.10617121
133CAMK2B0.10185645
134MAPK100.09605855
135PRKCA0.09502885
136TXK0.07676250

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000205.85560252
22-Oxocarboxylic acid metabolism_Homo sapiens_hsa012104.04957532
3Cardiac muscle contraction_Homo sapiens_hsa042603.92167251
4Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.54643587
5Dilated cardiomyopathy_Homo sapiens_hsa054143.48954109
6Propanoate metabolism_Homo sapiens_hsa006403.32196196
7Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.09595594
8Parkinsons disease_Homo sapiens_hsa050122.93130486
9Oxidative phosphorylation_Homo sapiens_hsa001902.92933621
10Fatty acid degradation_Homo sapiens_hsa000712.71391798
11Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.62586412
12Carbon metabolism_Homo sapiens_hsa012002.39346033
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.34086406
14Alzheimers disease_Homo sapiens_hsa050102.31316607
15Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.08515463
16Fatty acid metabolism_Homo sapiens_hsa012122.03961392
17Pyruvate metabolism_Homo sapiens_hsa006201.83976352
18Huntingtons disease_Homo sapiens_hsa050161.73157555
19Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.69991575
20Nitrogen metabolism_Homo sapiens_hsa009101.53854046
21Starch and sucrose metabolism_Homo sapiens_hsa005001.46464191
22Viral myocarditis_Homo sapiens_hsa054161.38777583
23Glucagon signaling pathway_Homo sapiens_hsa049221.37018475
24Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.34296882
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.31509299
26Insulin resistance_Homo sapiens_hsa049311.30922374
27Butanoate metabolism_Homo sapiens_hsa006501.27945274
28Insulin signaling pathway_Homo sapiens_hsa049101.24213566
29Adipocytokine signaling pathway_Homo sapiens_hsa049201.19788364
30Calcium signaling pathway_Homo sapiens_hsa040201.13430247
31cGMP-PKG signaling pathway_Homo sapiens_hsa040221.10662024
32Fatty acid elongation_Homo sapiens_hsa000621.09376807
33Biosynthesis of amino acids_Homo sapiens_hsa012301.07191871
34Circadian rhythm_Homo sapiens_hsa047101.06056687
35Oxytocin signaling pathway_Homo sapiens_hsa049211.04113349
36Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.01826496
37Linoleic acid metabolism_Homo sapiens_hsa005910.99402544
38Phototransduction_Homo sapiens_hsa047440.94210058
39Galactose metabolism_Homo sapiens_hsa000520.91032011
40AMPK signaling pathway_Homo sapiens_hsa041520.90738350
41Arginine and proline metabolism_Homo sapiens_hsa003300.87428228
42PPAR signaling pathway_Homo sapiens_hsa033200.86509197
43alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.85581876
44Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.83422322
45Type II diabetes mellitus_Homo sapiens_hsa049300.82253694
46Insulin secretion_Homo sapiens_hsa049110.77370521
47beta-Alanine metabolism_Homo sapiens_hsa004100.75975201
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.75626428
49Fructose and mannose metabolism_Homo sapiens_hsa000510.75039303
50Vascular smooth muscle contraction_Homo sapiens_hsa042700.74209659
51Tryptophan metabolism_Homo sapiens_hsa003800.72477021
52Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.68855096
53ABC transporters_Homo sapiens_hsa020100.66861208
54Renin secretion_Homo sapiens_hsa049240.65881881
55Gastric acid secretion_Homo sapiens_hsa049710.63367699
56Arginine biosynthesis_Homo sapiens_hsa002200.61846561
57HIF-1 signaling pathway_Homo sapiens_hsa040660.61389202
58Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.55220714
59Pancreatic secretion_Homo sapiens_hsa049720.54319079
60Focal adhesion_Homo sapiens_hsa045100.54155572
61Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.54078283
62Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52881390
63Lysine degradation_Homo sapiens_hsa003100.51010972
64Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.50395874
65GABAergic synapse_Homo sapiens_hsa047270.45739907
66Circadian entrainment_Homo sapiens_hsa047130.45059451
67cAMP signaling pathway_Homo sapiens_hsa040240.44786476
68Long-term depression_Homo sapiens_hsa047300.44592876
69Peroxisome_Homo sapiens_hsa041460.44137078
70Phenylalanine metabolism_Homo sapiens_hsa003600.43889977
71Tyrosine metabolism_Homo sapiens_hsa003500.42651801
72Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.42549054
73Fatty acid biosynthesis_Homo sapiens_hsa000610.41741541
74Aldosterone synthesis and secretion_Homo sapiens_hsa049250.41695651
75Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.41317223
76Tight junction_Homo sapiens_hsa045300.40702493
77Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.40596748
78Central carbon metabolism in cancer_Homo sapiens_hsa052300.39097744
79Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37987124
80Maturity onset diabetes of the young_Homo sapiens_hsa049500.37817309
81GnRH signaling pathway_Homo sapiens_hsa049120.37243542
82Purine metabolism_Homo sapiens_hsa002300.36997655
83Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.35139671
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.32686432
85Serotonergic synapse_Homo sapiens_hsa047260.32200108
86Histidine metabolism_Homo sapiens_hsa003400.32185111
87Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.30218929
88Fat digestion and absorption_Homo sapiens_hsa049750.30007136
89Cholinergic synapse_Homo sapiens_hsa047250.29295679
90Metabolic pathways_Homo sapiens_hsa011000.24166969
91FoxO signaling pathway_Homo sapiens_hsa040680.23603185
92Ether lipid metabolism_Homo sapiens_hsa005650.22485816
93Long-term potentiation_Homo sapiens_hsa047200.22266608
94mTOR signaling pathway_Homo sapiens_hsa041500.20807225
95Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.20154895
96Taste transduction_Homo sapiens_hsa047420.19987701
97Cysteine and methionine metabolism_Homo sapiens_hsa002700.19187048
98Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.18624342
99Dorso-ventral axis formation_Homo sapiens_hsa043200.18550945
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.17370931
101VEGF signaling pathway_Homo sapiens_hsa043700.16991724
102Amoebiasis_Homo sapiens_hsa051460.15974815
103Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.15419218
104Olfactory transduction_Homo sapiens_hsa047400.15045344
105Sulfur metabolism_Homo sapiens_hsa009200.15011590
106MAPK signaling pathway_Homo sapiens_hsa040100.14593339
107Glycerolipid metabolism_Homo sapiens_hsa005610.14581474
108Regulation of autophagy_Homo sapiens_hsa041400.14428528
109Salivary secretion_Homo sapiens_hsa049700.13684443
110Regulation of actin cytoskeleton_Homo sapiens_hsa048100.13408110
111Renal cell carcinoma_Homo sapiens_hsa052110.13000536
112Morphine addiction_Homo sapiens_hsa050320.12987114
113Platelet activation_Homo sapiens_hsa046110.12090031
114Pentose phosphate pathway_Homo sapiens_hsa000300.11879773
115Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.11109622
116Amphetamine addiction_Homo sapiens_hsa050310.09926195
117Dopaminergic synapse_Homo sapiens_hsa047280.09548571
118Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.09398194
119Ovarian steroidogenesis_Homo sapiens_hsa049130.09204819
120Adherens junction_Homo sapiens_hsa045200.08874884
121Gap junction_Homo sapiens_hsa045400.08679658
122ECM-receptor interaction_Homo sapiens_hsa045120.05836740
123Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.05063123

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »