Rank | Gene Set | Z-score |
---|---|---|
1 | sarcomere organization (GO:0045214) | 8.47127012 |
2 | muscle filament sliding (GO:0030049) | 7.90299944 |
3 | actin-myosin filament sliding (GO:0033275) | 7.90299944 |
4 | regulation of skeletal muscle contraction (GO:0014819) | 7.62508418 |
5 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 7.54741646 |
6 | myofibril assembly (GO:0030239) | 7.30151507 |
7 | cardiac myofibril assembly (GO:0055003) | 7.23547168 |
8 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 7.05860168 |
9 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 6.93153694 |
10 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 6.90291172 |
11 | actin-mediated cell contraction (GO:0070252) | 6.58797553 |
12 | tricarboxylic acid cycle (GO:0006099) | 6.33313352 |
13 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 6.21995908 |
14 | carnitine shuttle (GO:0006853) | 6.18986574 |
15 | plasma membrane repair (GO:0001778) | 6.09941029 |
16 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 6.08300095 |
17 | regulation of relaxation of muscle (GO:1901077) | 5.99551504 |
18 | cardiac muscle contraction (GO:0060048) | 5.98698373 |
19 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 5.94698751 |
20 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 5.81664726 |
21 | skeletal muscle contraction (GO:0003009) | 5.78223881 |
22 | regulation of actin filament-based movement (GO:1903115) | 5.77781201 |
23 | regulation of cell communication by electrical coupling (GO:0010649) | 5.76109569 |
24 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 5.72170764 |
25 | striated muscle contraction (GO:0006941) | 5.68548853 |
26 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 5.55800701 |
27 | cardiac muscle cell development (GO:0055013) | 5.48158076 |
28 | actomyosin structure organization (GO:0031032) | 5.37084912 |
29 | skeletal muscle adaptation (GO:0043501) | 5.33274880 |
30 | fatty acid transmembrane transport (GO:1902001) | 5.31879936 |
31 | skeletal muscle fiber development (GO:0048741) | 5.31579221 |
32 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 5.23754158 |
33 | cardiac cell development (GO:0055006) | 5.12550518 |
34 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 5.02596817 |
35 | creatine metabolic process (GO:0006600) | 4.99913525 |
36 | regulation of coenzyme metabolic process (GO:0051196) | 4.99894180 |
37 | regulation of cofactor metabolic process (GO:0051193) | 4.99894180 |
38 | carnitine transmembrane transport (GO:1902603) | 4.97033199 |
39 | actin filament-based movement (GO:0030048) | 4.92831612 |
40 | myotube cell development (GO:0014904) | 4.85153320 |
41 | ventricular cardiac muscle cell action potential (GO:0086005) | 4.77246152 |
42 | cardiac muscle hypertrophy (GO:0003300) | 4.68209502 |
43 | regulation of striated muscle contraction (GO:0006942) | 4.67755301 |
44 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 4.67325285 |
45 | carnitine transport (GO:0015879) | 4.59910548 |
46 | amino-acid betaine transport (GO:0015838) | 4.59910548 |
47 | cardiac muscle tissue morphogenesis (GO:0055008) | 4.57618268 |
48 | heart process (GO:0003015) | 4.57122527 |
49 | heart contraction (GO:0060047) | 4.57122527 |
50 | striated muscle hypertrophy (GO:0014897) | 4.54955040 |
51 | regulation of sarcomere organization (GO:0060297) | 4.54253915 |
52 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.44261746 |
53 | adult heart development (GO:0007512) | 4.42038574 |
54 | heart trabecula formation (GO:0060347) | 4.27125281 |
55 | response to inactivity (GO:0014854) | 4.26788747 |
56 | muscle tissue morphogenesis (GO:0060415) | 4.24788402 |
57 | skeletal muscle tissue development (GO:0007519) | 4.22588099 |
58 | regulation of membrane repolarization (GO:0060306) | 4.21338593 |
59 | muscle contraction (GO:0006936) | 4.14559081 |
60 | response to muscle activity (GO:0014850) | 4.11217649 |
61 | regulation of sulfur metabolic process (GO:0042762) | 4.10244538 |
62 | striated muscle atrophy (GO:0014891) | 4.08736929 |
63 | striated muscle adaptation (GO:0014888) | 4.07497807 |
64 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 4.04748432 |
65 | glycogen catabolic process (GO:0005980) | 4.03540333 |
66 | muscle hypertrophy (GO:0014896) | 3.99824393 |
67 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 3.93854033 |
68 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 3.93854033 |
69 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 3.93851109 |
70 | 2-oxoglutarate metabolic process (GO:0006103) | 3.93133086 |
71 | regulation of sequestering of triglyceride (GO:0010889) | 3.89817567 |
72 | muscle system process (GO:0003012) | 3.82785391 |
73 | cell communication involved in cardiac conduction (GO:0086065) | 3.77641855 |
74 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.77524625 |
75 | skeletal muscle tissue regeneration (GO:0043403) | 3.76611660 |
76 | glucan catabolic process (GO:0009251) | 3.76398820 |
77 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.75345268 |
78 | NADH metabolic process (GO:0006734) | 3.72775909 |
79 | regulation of cardiac muscle cell contraction (GO:0086004) | 3.70851980 |
80 | muscle cell fate commitment (GO:0042693) | 3.70252233 |
81 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.69392092 |
82 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.66123831 |
83 | striated muscle cell development (GO:0055002) | 3.65572644 |
84 | regulation of calcium ion transmembrane transport (GO:1903169) | 3.62739164 |
85 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 3.62739164 |
86 | regulation of cardiac muscle contraction (GO:0055117) | 3.60070058 |
87 | otic vesicle formation (GO:0030916) | 3.57728677 |
88 | positive regulation of cation channel activity (GO:2001259) | 3.57651466 |
89 | glycogen metabolic process (GO:0005977) | 3.56857660 |
90 | regulation of the force of heart contraction (GO:0002026) | 3.56746031 |
91 | relaxation of muscle (GO:0090075) | 3.56095105 |
92 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.53372555 |
93 | respiratory electron transport chain (GO:0022904) | 3.53293766 |
94 | cardiac muscle adaptation (GO:0014887) | 3.53045380 |
95 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 3.53045380 |
96 | muscle hypertrophy in response to stress (GO:0003299) | 3.53045380 |
97 | cellular polysaccharide catabolic process (GO:0044247) | 3.51653147 |
98 | cardiac muscle cell action potential (GO:0086001) | 3.51215484 |
99 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 3.50646672 |
100 | muscle atrophy (GO:0014889) | 3.49536249 |
101 | glucan metabolic process (GO:0044042) | 3.49306580 |
102 | cellular glucan metabolic process (GO:0006073) | 3.49306580 |
103 | oxidative phosphorylation (GO:0006119) | 3.48939584 |
104 | muscle cell cellular homeostasis (GO:0046716) | 3.47871996 |
105 | negative regulation of protein localization to cell surface (GO:2000009) | 3.43920732 |
106 | electron transport chain (GO:0022900) | 3.43359907 |
107 | aspartate family amino acid catabolic process (GO:0009068) | 3.42692002 |
108 | relaxation of cardiac muscle (GO:0055119) | 3.42518113 |
109 | muscle fiber development (GO:0048747) | 3.41980471 |
110 | muscle adaptation (GO:0043500) | 3.37270894 |
111 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.36583164 |
112 | negative regulation of potassium ion transport (GO:0043267) | 3.36352697 |
113 | response to caffeine (GO:0031000) | 3.36158886 |
114 | response to activity (GO:0014823) | 3.36053511 |
115 | muscle structure development (GO:0061061) | 3.33302917 |
116 | muscle organ development (GO:0007517) | 3.31182605 |
117 | polysaccharide catabolic process (GO:0000272) | 3.30500196 |
118 | regulation of heart rate (GO:0002027) | 3.30093433 |
119 | detection of calcium ion (GO:0005513) | 3.29032650 |
120 | glucan biosynthetic process (GO:0009250) | 3.28489342 |
121 | glycogen biosynthetic process (GO:0005978) | 3.28489342 |
122 | regulation of muscle system process (GO:0090257) | 3.24828461 |
123 | muscle organ morphogenesis (GO:0048644) | 3.24436049 |
124 | myotube differentiation (GO:0014902) | 3.22326957 |
125 | regulation of ATPase activity (GO:0043462) | 3.22007689 |
126 | regulation of ATP catabolic process (GO:1903289) | 3.22007689 |
127 | neuronal action potential propagation (GO:0019227) | 3.18392090 |
128 | regulation of muscle contraction (GO:0006937) | 3.15690915 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 5.23453638 |
2 | * EP300_21415370_ChIP-Seq_HL-1_Mouse | 4.15094118 |
3 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.73911774 |
4 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 3.68219483 |
5 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 3.65533692 |
6 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 3.65533692 |
7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.63989205 |
8 | * TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 3.27398881 |
9 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.09308660 |
10 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.95530388 |
11 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 2.63388307 |
12 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.48887822 |
13 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.41981424 |
14 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.12067020 |
15 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.08760042 |
16 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.04566732 |
17 | * PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.91515597 |
18 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.87258855 |
19 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.79295582 |
20 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.63487414 |
21 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.61128741 |
22 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.60345827 |
23 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.59799096 |
24 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.59662009 |
25 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.52020353 |
26 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.51067857 |
27 | VDR_22108803_ChIP-Seq_LS180_Human | 1.48848334 |
28 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.46595270 |
29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.44386629 |
30 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.43801001 |
31 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.40203239 |
32 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.39260157 |
33 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.36380861 |
34 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.35539973 |
35 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.32840588 |
36 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.32284374 |
37 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.31694007 |
38 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.31586266 |
39 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.30160491 |
40 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.29108667 |
41 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.27437550 |
42 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.27375691 |
43 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.26847601 |
44 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.24307418 |
45 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.20407388 |
46 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.20164814 |
47 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.20164814 |
48 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.19024854 |
49 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.18938744 |
50 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.18883041 |
51 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.16489378 |
52 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.15681704 |
53 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.14332646 |
54 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.12622545 |
55 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.12610302 |
56 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.09803726 |
57 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.09046713 |
58 | FUS_26573619_Chip-Seq_HEK293_Human | 1.07556103 |
59 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.07177753 |
60 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.07099190 |
61 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.06450198 |
62 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.06388371 |
63 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04448879 |
64 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.03848139 |
65 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.03001357 |
66 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.02598822 |
67 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.02520438 |
68 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.01598146 |
69 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.01029975 |
70 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.99889049 |
71 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.99821870 |
72 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.99545104 |
73 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.99444342 |
74 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.97156241 |
75 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.96558429 |
76 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.95958313 |
77 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.95958313 |
78 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.95651734 |
79 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.95629074 |
80 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.95538351 |
81 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.95394508 |
82 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.94763473 |
83 | TCF4_23295773_ChIP-Seq_U87_Human | 0.94300536 |
84 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.93090732 |
85 | * SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.92490200 |
86 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.91246629 |
87 | CJUN_26792858_Chip-Seq_BT549_Human | 0.91229074 |
88 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.91085780 |
89 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.91009509 |
90 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.90125603 |
91 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.89985217 |
92 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.89470574 |
93 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.88599182 |
94 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.88539260 |
95 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.87469165 |
96 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.87418624 |
97 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.87258571 |
98 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.86166790 |
99 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.85801608 |
100 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.85636595 |
101 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.85141987 |
102 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.84945235 |
103 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.84263373 |
104 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.83736993 |
105 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.83626104 |
106 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.83447545 |
107 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.83151127 |
108 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.82862938 |
109 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.82666066 |
110 | TBL1_22424771_ChIP-Seq_293T_Human | 0.82357341 |
111 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.81798429 |
112 | CBP_21632823_ChIP-Seq_H3396_Human | 0.81452567 |
113 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.81337706 |
114 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.81245082 |
115 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.81239340 |
116 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.81239340 |
117 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.81137345 |
118 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.81117289 |
119 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.80706765 |
120 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.80139165 |
121 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.79918416 |
122 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.79285032 |
123 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.78381767 |
124 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.77552672 |
125 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.77438274 |
126 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.77370903 |
127 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.76744385 |
128 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.76340479 |
129 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.74829652 |
130 | P68_20966046_ChIP-Seq_HELA_Human | 0.74459578 |
131 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.74455496 |
132 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.73985552 |
133 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.73023442 |
134 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.73010616 |
135 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.72892533 |
136 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.72866498 |
137 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.72293385 |
138 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.72227343 |
139 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.72227343 |
140 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.71669495 |
141 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.71124717 |
142 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.70816012 |
143 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.70815375 |
144 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.70426571 |
145 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.70188526 |
146 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.69911032 |
147 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.69456954 |
148 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.68378982 |
149 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.67983917 |
150 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.67864062 |
151 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.67863345 |
152 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.66647643 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003646_muscle_fatigue | 6.84503269 |
2 | MP0002837_dystrophic_cardiac_calcinosis | 5.95627154 |
3 | MP0000751_myopathy | 5.41107721 |
4 | MP0004084_abnormal_cardiac_muscle | 4.68120366 |
5 | MP0000749_muscle_degeneration | 4.67715741 |
6 | MP0004036_abnormal_muscle_relaxation | 4.41295336 |
7 | MP0004145_abnormal_muscle_electrophysio | 4.29218401 |
8 | MP0004215_abnormal_myocardial_fiber | 4.07015885 |
9 | MP0005330_cardiomyopathy | 3.37221550 |
10 | MP0004087_abnormal_muscle_fiber | 3.25029155 |
11 | MP0002106_abnormal_muscle_physiology | 3.19050294 |
12 | MP0000750_abnormal_muscle_regeneration | 3.13015450 |
13 | MP0004130_abnormal_muscle_cell | 3.09491184 |
14 | MP0005620_abnormal_muscle_contractility | 2.94677355 |
15 | MP0002269_muscular_atrophy | 2.84622984 |
16 | MP0000747_muscle_weakness | 2.69941138 |
17 | MP0002972_abnormal_cardiac_muscle | 2.67457632 |
18 | MP0005369_muscle_phenotype | 2.62351567 |
19 | MP0000759_abnormal_skeletal_muscle | 2.60375732 |
20 | MP0004484_altered_response_of | 2.47010353 |
21 | MP0008775_abnormal_heart_ventricle | 2.43474543 |
22 | MP0003137_abnormal_impulse_conducting | 2.41401079 |
23 | MP0004233_abnormal_muscle_weight | 2.26146145 |
24 | MP0010630_abnormal_cardiac_muscle | 2.25693837 |
25 | MP0001544_abnormal_cardiovascular_syste | 2.22316204 |
26 | MP0005385_cardiovascular_system_phenoty | 2.22316204 |
27 | MP0006036_abnormal_mitochondrial_physio | 1.96959918 |
28 | MP0006138_congestive_heart_failure | 1.88525944 |
29 | MP0003221_abnormal_cardiomyocyte_apopto | 1.76368777 |
30 | MP0005666_abnormal_adipose_tissue | 1.68954614 |
31 | MP0004085_abnormal_heartbeat | 1.66555294 |
32 | MP0002332_abnormal_exercise_endurance | 1.66086117 |
33 | MP0003828_pulmonary_edema | 1.61667058 |
34 | MP0005670_abnormal_white_adipose | 1.59910413 |
35 | MP0004510_myositis | 1.48721752 |
36 | MP0004185_abnormal_adipocyte_glucose | 1.34465312 |
37 | MP0002127_abnormal_cardiovascular_syste | 1.34451972 |
38 | MP0002108_abnormal_muscle_morphology | 1.26493026 |
39 | MP0003950_abnormal_plasma_membrane | 1.23064415 |
40 | MP0002234_abnormal_pharynx_morphology | 1.11620019 |
41 | MP0005375_adipose_tissue_phenotype | 1.11460014 |
42 | MP0000343_altered_response_to | 1.07428774 |
43 | MP0000733_abnormal_muscle_development | 1.06658697 |
44 | MP0006035_abnormal_mitochondrial_morpho | 1.04523944 |
45 | MP0004270_analgesia | 1.03835719 |
46 | MP0000266_abnormal_heart_morphology | 0.99289326 |
47 | MP0005165_increased_susceptibility_to | 0.97689524 |
48 | MP0004043_abnormal_pH_regulation | 0.94573805 |
49 | MP0003567_abnormal_fetal_cardiomyocyte | 0.90236966 |
50 | MP0005266_abnormal_metabolism | 0.87175977 |
51 | MP0001661_extended_life_span | 0.84095153 |
52 | MP0002971_abnormal_brown_adipose | 0.83500893 |
53 | MP0000230_abnormal_systemic_arterial | 0.80626683 |
54 | MP0005623_abnormal_meninges_morphology | 0.79714466 |
55 | MP0005410_abnormal_fertilization | 0.70072285 |
56 | MP0010368_abnormal_lymphatic_system | 0.69117363 |
57 | MP0003879_abnormal_hair_cell | 0.67799873 |
58 | MP0003279_aneurysm | 0.66636816 |
59 | MP0003806_abnormal_nucleotide_metabolis | 0.64835010 |
60 | MP0005451_abnormal_body_composition | 0.64215280 |
61 | MP0004142_abnormal_muscle_tone | 0.63381729 |
62 | MP0002128_abnormal_blood_circulation | 0.63256443 |
63 | MP0008961_abnormal_basal_metabolism | 0.59733758 |
64 | MP0002638_abnormal_pupillary_reflex | 0.59235081 |
65 | MP0003195_calcinosis | 0.57928544 |
66 | MP0004147_increased_porphyrin_level | 0.57036893 |
67 | MP0000372_irregular_coat_pigmentation | 0.56877994 |
68 | MP0001879_abnormal_lymphatic_vessel | 0.56490197 |
69 | MP0000013_abnormal_adipose_tissue | 0.56229348 |
70 | MP0000003_abnormal_adipose_tissue | 0.55731299 |
71 | MP0002078_abnormal_glucose_homeostasis | 0.55679996 |
72 | MP0009250_abnormal_appendicular_skeleto | 0.49478980 |
73 | MP0005187_abnormal_penis_morphology | 0.46685906 |
74 | MP0005319_abnormal_enzyme/_coenzyme | 0.43870443 |
75 | MP0005334_abnormal_fat_pad | 0.43000677 |
76 | MP0002909_abnormal_adrenal_gland | 0.40677052 |
77 | MP0004134_abnormal_chest_morphology | 0.40030844 |
78 | MP0005376_homeostasis/metabolism_phenot | 0.39243946 |
79 | MP0000767_abnormal_smooth_muscle | 0.38652188 |
80 | MP0002160_abnormal_reproductive_system | 0.38278444 |
81 | MP0003566_abnormal_cell_adhesion | 0.37856307 |
82 | MP0005535_abnormal_body_temperature | 0.37221498 |
83 | MP0002876_abnormal_thyroid_physiology | 0.36107645 |
84 | MP0001485_abnormal_pinna_reflex | 0.33218651 |
85 | MP0003705_abnormal_hypodermis_morpholog | 0.33008942 |
86 | MP0001853_heart_inflammation | 0.32380247 |
87 | MP0002734_abnormal_mechanical_nocicepti | 0.31808263 |
88 | MP0001727_abnormal_embryo_implantation | 0.30163411 |
89 | MP0002925_abnormal_cardiovascular_devel | 0.29549039 |
90 | MP0003656_abnormal_erythrocyte_physiolo | 0.29547602 |
91 | MP0003045_fibrosis | 0.29135265 |
92 | MP0002272_abnormal_nervous_system | 0.28638902 |
93 | MP0003948_abnormal_gas_homeostasis | 0.28596498 |
94 | MP0009115_abnormal_fat_cell | 0.28390253 |
95 | MP0001984_abnormal_olfaction | 0.27961694 |
96 | MP0000579_abnormal_nail_morphology | 0.27959548 |
97 | MP0003136_yellow_coat_color | 0.27093467 |
98 | MP0001440_abnormal_grooming_behavior | 0.26619218 |
99 | MP0005645_abnormal_hypothalamus_physiol | 0.26549791 |
100 | MP0001765_abnormal_ion_homeostasis | 0.26423932 |
101 | MP0005646_abnormal_pituitary_gland | 0.26396276 |
102 | MP0005423_abnormal_somatic_nervous | 0.26095341 |
103 | MP0005452_abnormal_adipose_tissue | 0.25784251 |
104 | MP0001614_abnormal_blood_vessel | 0.25690856 |
105 | MP0001784_abnormal_fluid_regulation | 0.25464182 |
106 | MP0000762_abnormal_tongue_morphology | 0.24920326 |
107 | MP0002118_abnormal_lipid_homeostasis | 0.24789472 |
108 | MP0002896_abnormal_bone_mineralization | 0.24587990 |
109 | MP0002114_abnormal_axial_skeleton | 0.24586418 |
110 | MP0010030_abnormal_orbit_morphology | 0.24112675 |
111 | MP0005167_abnormal_blood-brain_barrier | 0.23323673 |
112 | MP0002066_abnormal_motor_capabilities/c | 0.22848362 |
113 | MP0003011_delayed_dark_adaptation | 0.22629981 |
114 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.22417655 |
115 | MP0009384_cardiac_valve_regurgitation | 0.22157877 |
116 | MP0006072_abnormal_retinal_apoptosis | 0.19975215 |
117 | MP0005332_abnormal_amino_acid | 0.18856343 |
118 | MP0008569_lethality_at_weaning | 0.18766853 |
119 | MP0009780_abnormal_chondrocyte_physiolo | 0.18575333 |
120 | MP0005386_behavior/neurological_phenoty | 0.18043874 |
121 | MP0004924_abnormal_behavior | 0.18043874 |
122 | MP0001299_abnormal_eye_distance/ | 0.17701028 |
123 | MP0002822_catalepsy | 0.15762682 |
124 | MP0005275_abnormal_skin_tensile | 0.15727763 |
125 | MP0008874_decreased_physiological_sensi | 0.15015588 |
126 | MP0002970_abnormal_white_adipose | 0.15006003 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Exercise-induced myalgia (HP:0003738) | 7.65876790 |
2 | Exercise-induced muscle cramps (HP:0003710) | 7.29605325 |
3 | Muscle hypertrophy of the lower extremities (HP:0008968) | 7.18650499 |
4 | Calf muscle hypertrophy (HP:0008981) | 7.09699983 |
5 | Sudden death (HP:0001699) | 6.59363134 |
6 | Muscle fiber splitting (HP:0003555) | 6.03991694 |
7 | Myoglobinuria (HP:0002913) | 5.86947468 |
8 | Ventricular tachycardia (HP:0004756) | 5.71391971 |
9 | Hyporeflexia of lower limbs (HP:0002600) | 5.27534682 |
10 | Abnormality of the calf musculature (HP:0001430) | 5.26120915 |
11 | Muscle fiber inclusion bodies (HP:0100299) | 5.07674206 |
12 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 4.91450848 |
13 | Difficulty running (HP:0009046) | 4.88029707 |
14 | Atrial fibrillation (HP:0005110) | 4.84891953 |
15 | Abnormality of the left ventricular outflow tract (HP:0011103) | 4.73020372 |
16 | Subaortic stenosis (HP:0001682) | 4.73020372 |
17 | Rhabdomyolysis (HP:0003201) | 4.66036928 |
18 | Primary atrial arrhythmia (HP:0001692) | 4.51124824 |
19 | EMG: myopathic abnormalities (HP:0003458) | 4.48797707 |
20 | Increased connective tissue (HP:0009025) | 4.43335129 |
21 | Supraventricular tachycardia (HP:0004755) | 4.34865698 |
22 | Lipoatrophy (HP:0100578) | 4.24818507 |
23 | Supraventricular arrhythmia (HP:0005115) | 4.23966339 |
24 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 4.13955519 |
25 | Nemaline bodies (HP:0003798) | 4.13891346 |
26 | Myotonia (HP:0002486) | 4.10856582 |
27 | Bundle branch block (HP:0011710) | 4.09415912 |
28 | Right ventricular cardiomyopathy (HP:0011663) | 3.96048782 |
29 | Asymmetric septal hypertrophy (HP:0001670) | 3.88810913 |
30 | Muscle stiffness (HP:0003552) | 3.87887639 |
31 | Syncope (HP:0001279) | 3.80701020 |
32 | Type 1 muscle fiber predominance (HP:0003803) | 3.72686917 |
33 | Dilated cardiomyopathy (HP:0001644) | 3.66772637 |
34 | Palpitations (HP:0001962) | 3.62986831 |
35 | Difficulty climbing stairs (HP:0003551) | 3.40540344 |
36 | Heart block (HP:0012722) | 3.39350127 |
37 | Prolonged QT interval (HP:0001657) | 3.33156827 |
38 | Ventricular arrhythmia (HP:0004308) | 3.23895586 |
39 | Abnormal atrioventricular conduction (HP:0005150) | 3.19460076 |
40 | Distal arthrogryposis (HP:0005684) | 3.11270312 |
41 | Atrioventricular block (HP:0001678) | 3.06923217 |
42 | Myopathic facies (HP:0002058) | 3.03293742 |
43 | Abnormal finger flexion creases (HP:0006143) | 3.00258491 |
44 | Deformed tarsal bones (HP:0008119) | 2.99888799 |
45 | Areflexia of lower limbs (HP:0002522) | 2.97290677 |
46 | Increased variability in muscle fiber diameter (HP:0003557) | 2.95352165 |
47 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.92346478 |
48 | Distal lower limb muscle weakness (HP:0009053) | 2.89888542 |
49 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.86657723 |
50 | Ventricular fibrillation (HP:0001663) | 2.80276770 |
51 | Malignant hyperthermia (HP:0002047) | 2.77088249 |
52 | Round ear (HP:0100830) | 2.73940292 |
53 | Rimmed vacuoles (HP:0003805) | 2.66676397 |
54 | Left ventricular hypertrophy (HP:0001712) | 2.65491125 |
55 | Neck muscle weakness (HP:0000467) | 2.62987422 |
56 | Hypoplastic ischia (HP:0003175) | 2.57502820 |
57 | Ketoacidosis (HP:0001993) | 2.48863712 |
58 | Ulnar deviation of the wrist (HP:0003049) | 2.47554596 |
59 | Abnormal EKG (HP:0003115) | 2.47039415 |
60 | Bulbar palsy (HP:0001283) | 2.40843055 |
61 | Hepatic necrosis (HP:0002605) | 2.38079698 |
62 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.37324594 |
63 | Weak cry (HP:0001612) | 2.36286413 |
64 | Limb-girdle muscle atrophy (HP:0003797) | 2.35430486 |
65 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.34513627 |
66 | Abnormality of alanine metabolism (HP:0010916) | 2.34513627 |
67 | Hyperalaninemia (HP:0003348) | 2.34513627 |
68 | Acute necrotizing encephalopathy (HP:0006965) | 2.30319386 |
69 | Muscular dystrophy (HP:0003560) | 2.29862224 |
70 | Hyperkalemia (HP:0002153) | 2.24444707 |
71 | Abnormality of the ischium (HP:0003174) | 2.24174727 |
72 | Distal lower limb amyotrophy (HP:0008944) | 2.21274034 |
73 | Abnormality of the shoulder girdle musculature (HP:0001435) | 2.20091057 |
74 | Testicular atrophy (HP:0000029) | 2.17084752 |
75 | Waddling gait (HP:0002515) | 2.16222919 |
76 | Gowers sign (HP:0003391) | 2.15463748 |
77 | Increased muscle lipid content (HP:0009058) | 2.15133101 |
78 | EMG: neuropathic changes (HP:0003445) | 2.10696956 |
79 | Fetal akinesia sequence (HP:0001989) | 2.10068561 |
80 | Generalized muscle weakness (HP:0003324) | 2.09544702 |
81 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.09292691 |
82 | Dicarboxylic aciduria (HP:0003215) | 2.09009767 |
83 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.09009767 |
84 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.08010228 |
85 | Facial diplegia (HP:0001349) | 2.06579093 |
86 | Absent phalangeal crease (HP:0006109) | 2.04335902 |
87 | Hypoglycemic coma (HP:0001325) | 2.04281963 |
88 | Palmoplantar keratoderma (HP:0000982) | 2.03827719 |
89 | Ragged-red muscle fibers (HP:0003200) | 2.02673863 |
90 | Exercise intolerance (HP:0003546) | 2.02266443 |
91 | Hip contracture (HP:0003273) | 2.01734389 |
92 | Acute encephalopathy (HP:0006846) | 2.01725990 |
93 | Abnormality of the neuromuscular junction (HP:0003398) | 2.01566091 |
94 | Fatigable weakness (HP:0003473) | 2.01566091 |
95 | Abnormality of the foot musculature (HP:0001436) | 2.01391814 |
96 | Hepatocellular necrosis (HP:0001404) | 2.00621617 |
97 | Proximal amyotrophy (HP:0007126) | 1.99386821 |
98 | Limb-girdle muscle weakness (HP:0003325) | 1.96734609 |
99 | Large for gestational age (HP:0001520) | 1.95770015 |
100 | Frequent falls (HP:0002359) | 1.93759515 |
101 | Slender build (HP:0001533) | 1.93416812 |
102 | Calcaneovalgus deformity (HP:0001848) | 1.91856860 |
103 | Ketosis (HP:0001946) | 1.90522336 |
104 | Spinal rigidity (HP:0003306) | 1.89096430 |
105 | Progressive muscle weakness (HP:0003323) | 1.88864965 |
106 | Progressive macrocephaly (HP:0004481) | 1.87838343 |
107 | Cerebral edema (HP:0002181) | 1.87096057 |
108 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.84977826 |
109 | Mitochondrial inheritance (HP:0001427) | 1.83369355 |
110 | Increased intramyocellular lipid droplets (HP:0012240) | 1.82786788 |
111 | Toxemia of pregnancy (HP:0100603) | 1.82352405 |
112 | Lactic acidosis (HP:0003128) | 1.81843792 |
113 | Central scotoma (HP:0000603) | 1.79238149 |
114 | Oligomenorrhea (HP:0000876) | 1.77721949 |
115 | Increased CSF lactate (HP:0002490) | 1.76859281 |
116 | Scapular winging (HP:0003691) | 1.76683102 |
117 | Foot dorsiflexor weakness (HP:0009027) | 1.76677363 |
118 | Nonprogressive disorder (HP:0003680) | 1.74318022 |
119 | Respiratory insufficiency due to muscle weakness (HP:0002747) | 1.71697169 |
120 | Abnormality of the calcaneus (HP:0008364) | 1.70840482 |
121 | Paralysis (HP:0003470) | 1.67774182 |
122 | Type 2 muscle fiber atrophy (HP:0003554) | 1.50979556 |
123 | Lower limb amyotrophy (HP:0007210) | 1.47549006 |
124 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.46994109 |
125 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.46994109 |
126 | Ulnar deviation of finger (HP:0009465) | 1.44434000 |
127 | Long clavicles (HP:0000890) | 1.38996689 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TTN | 6.52850820 |
2 | OBSCN | 5.12465844 |
3 | PHKG1 | 4.99011749 |
4 | PHKG2 | 4.99011749 |
5 | PDK4 | 4.17152787 |
6 | PDK3 | 4.17152787 |
7 | PDK2 | 2.68341457 |
8 | LMTK2 | 2.66162053 |
9 | DMPK | 2.61094286 |
10 | PINK1 | 2.48066618 |
11 | BCKDK | 2.32568889 |
12 | MUSK | 2.31958911 |
13 | MYLK | 2.31411683 |
14 | PIK3CA | 2.10556074 |
15 | NEK1 | 2.07709767 |
16 | TRIB3 | 2.03048762 |
17 | STK24 | 1.84275609 |
18 | PKN2 | 1.82517368 |
19 | NME1 | 1.74758947 |
20 | MAP3K7 | 1.56964854 |
21 | TIE1 | 1.50621977 |
22 | GRK7 | 1.49671531 |
23 | MAP2K3 | 1.37939457 |
24 | MARK1 | 1.31034819 |
25 | WNK4 | 1.24289462 |
26 | MAPK12 | 1.21537742 |
27 | PIK3CG | 1.15865478 |
28 | LIMK1 | 1.11983635 |
29 | PRKAA2 | 1.07105242 |
30 | PRKAA1 | 1.00246181 |
31 | CAMK2D | 0.97822664 |
32 | STK38L | 0.93845855 |
33 | PRKD1 | 0.93564690 |
34 | ZAK | 0.88567075 |
35 | INSRR | 0.88561054 |
36 | TRPM7 | 0.88219097 |
37 | PAK3 | 0.85437575 |
38 | EEF2K | 0.81511475 |
39 | PKN1 | 0.80336464 |
40 | MAP3K9 | 0.77363000 |
41 | ILK | 0.75100019 |
42 | NEK9 | 0.74091411 |
43 | MAP2K4 | 0.73918868 |
44 | RIPK1 | 0.70253451 |
45 | PRKD3 | 0.70116428 |
46 | WNK1 | 0.68565110 |
47 | ERBB3 | 0.67428292 |
48 | STK39 | 0.66971100 |
49 | MOS | 0.66293258 |
50 | ROCK1 | 0.65326625 |
51 | MAP2K6 | 0.64068894 |
52 | STK38 | 0.62793347 |
53 | MAPKAPK3 | 0.60481980 |
54 | CCNB1 | 0.56588184 |
55 | TGFBR2 | 0.55469239 |
56 | CAMK4 | 0.55446211 |
57 | MAP3K5 | 0.54373039 |
58 | MAP2K1 | 0.53170955 |
59 | STK4 | 0.52756027 |
60 | ICK | 0.52135252 |
61 | FRK | 0.51828209 |
62 | CAMK2B | 0.48862172 |
63 | EPHB1 | 0.48418420 |
64 | MAPK4 | 0.48086773 |
65 | CAMK2G | 0.47202409 |
66 | CAMK2A | 0.46518127 |
67 | TNIK | 0.46063377 |
68 | SGK494 | 0.45546360 |
69 | SGK223 | 0.45546360 |
70 | DYRK1B | 0.43534284 |
71 | PRKACB | 0.43384480 |
72 | AKT2 | 0.40743934 |
73 | CAMK1 | 0.40174880 |
74 | PDPK1 | 0.39819545 |
75 | PRKACA | 0.39751763 |
76 | MAPK13 | 0.39371815 |
77 | FLT3 | 0.37583765 |
78 | CDC42BPA | 0.37514069 |
79 | MARK3 | 0.37404133 |
80 | PTK2B | 0.37070483 |
81 | LATS1 | 0.36376588 |
82 | PDK1 | 0.36035074 |
83 | NLK | 0.33424129 |
84 | PRKACG | 0.33127910 |
85 | MAP3K3 | 0.32689923 |
86 | PDGFRA | 0.32505352 |
87 | PTK6 | 0.30968030 |
88 | ROCK2 | 0.30607175 |
89 | RPS6KB1 | 0.29610064 |
90 | SGK1 | 0.29523515 |
91 | RPS6KC1 | 0.28450896 |
92 | RPS6KL1 | 0.28450896 |
93 | GRK1 | 0.27059951 |
94 | MAPK11 | 0.26170392 |
95 | KDR | 0.25046740 |
96 | PRKCE | 0.24836532 |
97 | OXSR1 | 0.23686031 |
98 | MAPK10 | 0.22467333 |
99 | RPS6KA1 | 0.22134065 |
100 | PRKG1 | 0.21860442 |
101 | RPS6KA6 | 0.21834121 |
102 | CASK | 0.21563808 |
103 | MAPK7 | 0.20968102 |
104 | SGK3 | 0.20291685 |
105 | EIF2AK3 | 0.19849544 |
106 | LATS2 | 0.19527483 |
107 | CAMK1G | 0.18919263 |
108 | TAOK1 | 0.18805084 |
109 | RPS6KA3 | 0.18161129 |
110 | MAP3K1 | 0.17787179 |
111 | MAP3K13 | 0.17523761 |
112 | JAK1 | 0.16576279 |
113 | PRKCH | 0.16389056 |
114 | DAPK2 | 0.14812740 |
115 | EPHB2 | 0.14762962 |
116 | SIK1 | 0.14061755 |
117 | RPS6KB2 | 0.13363483 |
118 | RPS6KA2 | 0.13025613 |
119 | MTOR | 0.11711715 |
120 | MAP3K6 | 0.10844483 |
121 | ABL2 | 0.10022080 |
122 | BMPR1B | 0.09798531 |
123 | PLK2 | 0.09353019 |
124 | PAK6 | 0.09051008 |
125 | MAPK9 | 0.08523998 |
126 | STK11 | 0.08025999 |
127 | PRKCA | 0.07511162 |
128 | GSK3B | 0.07221799 |
129 | MAP3K4 | 0.06989399 |
130 | ADRBK2 | 0.06765025 |
131 | SGK2 | 0.06486848 |
132 | ADRBK1 | 0.06017159 |
133 | CDK19 | 0.05996124 |
134 | AKT3 | 0.05584005 |
135 | MAPK8 | 0.05515913 |
136 | PRKCQ | 0.05373229 |
137 | JAK2 | 0.05184001 |
138 | RET | 0.04751046 |
139 | DAPK3 | 0.03560667 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 5.67694111 |
2 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 4.00062178 |
3 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.98326711 |
4 | Propanoate metabolism_Homo sapiens_hsa00640 | 3.71937385 |
5 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 3.67091047 |
6 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 3.53328570 |
7 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.13338873 |
8 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.93555008 |
9 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.84435221 |
10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.67598277 |
11 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.55935453 |
12 | Carbon metabolism_Homo sapiens_hsa01200 | 2.48324325 |
13 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.43491345 |
14 | Fatty acid metabolism_Homo sapiens_hsa01212 | 2.21002428 |
15 | Alzheimers disease_Homo sapiens_hsa05010 | 2.07225582 |
16 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.05090381 |
17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.91734333 |
18 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.64709503 |
19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.62423015 |
20 | Viral myocarditis_Homo sapiens_hsa05416 | 1.59225614 |
21 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.55063975 |
22 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.53383563 |
23 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.48421830 |
24 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.41204320 |
25 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.41145520 |
26 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.34864989 |
27 | Insulin resistance_Homo sapiens_hsa04931 | 1.29511122 |
28 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.28121085 |
29 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.24569640 |
30 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.20081564 |
31 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.17350955 |
32 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.11154769 |
33 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.09887713 |
34 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.09374560 |
35 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.09191116 |
36 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.01313994 |
37 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.99456900 |
38 | Circadian rhythm_Homo sapiens_hsa04710 | 0.96457503 |
39 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.95138966 |
40 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.94270632 |
41 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.89041269 |
42 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.88540214 |
43 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.80601737 |
44 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.79365548 |
45 | Lysine degradation_Homo sapiens_hsa00310 | 0.77576274 |
46 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.75251120 |
47 | Olfactory transduction_Homo sapiens_hsa04740 | 0.73022367 |
48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.72845438 |
49 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.67787986 |
50 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.66706117 |
51 | Galactose metabolism_Homo sapiens_hsa00052 | 0.66493629 |
52 | Focal adhesion_Homo sapiens_hsa04510 | 0.65551655 |
53 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.62568711 |
54 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.62292699 |
55 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.62275952 |
56 | Salivary secretion_Homo sapiens_hsa04970 | 0.62007810 |
57 | Long-term potentiation_Homo sapiens_hsa04720 | 0.61279595 |
58 | Renin secretion_Homo sapiens_hsa04924 | 0.60209461 |
59 | Sulfur relay system_Homo sapiens_hsa04122 | 0.57871380 |
60 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.57169236 |
61 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.53895751 |
62 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.51052942 |
63 | Tight junction_Homo sapiens_hsa04530 | 0.50645132 |
64 | Insulin secretion_Homo sapiens_hsa04911 | 0.50311172 |
65 | Phototransduction_Homo sapiens_hsa04744 | 0.48618490 |
66 | Peroxisome_Homo sapiens_hsa04146 | 0.48443924 |
67 | Histidine metabolism_Homo sapiens_hsa00340 | 0.48046183 |
68 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.42018695 |
69 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.41715423 |
70 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.40925158 |
71 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.39616668 |
72 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.39554096 |
73 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.39202284 |
74 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.37730922 |
75 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.37145340 |
76 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.36326222 |
77 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.35552440 |
78 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.33868671 |
79 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.29132039 |
80 | Adherens junction_Homo sapiens_hsa04520 | 0.28652735 |
81 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.27186365 |
82 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.27157586 |
83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.26913647 |
84 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.26761205 |
85 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.25710422 |
86 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.25429933 |
87 | Metabolic pathways_Homo sapiens_hsa01100 | 0.25427075 |
88 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.25091942 |
89 | Long-term depression_Homo sapiens_hsa04730 | 0.23478463 |
90 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.22504916 |
91 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.22121770 |
92 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.21117537 |
93 | Purine metabolism_Homo sapiens_hsa00230 | 0.21082783 |
94 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.20472145 |
95 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.20391695 |
96 | Amoebiasis_Homo sapiens_hsa05146 | 0.19927445 |
97 | Morphine addiction_Homo sapiens_hsa05032 | 0.19749482 |
98 | Circadian entrainment_Homo sapiens_hsa04713 | 0.19607904 |
99 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.19535815 |
100 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.19329895 |
101 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.19295386 |
102 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.19079226 |
103 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.17961791 |
104 | GABAergic synapse_Homo sapiens_hsa04727 | 0.17480885 |
105 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.16323103 |
106 | Platelet activation_Homo sapiens_hsa04611 | 0.14931952 |
107 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.14796053 |
108 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.13122745 |
109 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.12556340 |
110 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.11552274 |
111 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.10762387 |
112 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.09879374 |
113 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.09854569 |
114 | ABC transporters_Homo sapiens_hsa02010 | 0.08625023 |
115 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.06585442 |
116 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.06103316 |
117 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.05587181 |
118 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.03544171 |
119 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.03206316 |
120 | Gap junction_Homo sapiens_hsa04540 | -0.0266439 |
121 | Bile secretion_Homo sapiens_hsa04976 | -0.0150550 |
122 | Taste transduction_Homo sapiens_hsa04742 | -0.0020126 |