Rank | Gene Set | Z-score |
---|---|---|
1 | multicellular organism reproduction (GO:0032504) | 9.31004976 |
2 | piRNA metabolic process (GO:0034587) | 9.30704514 |
3 | binding of sperm to zona pellucida (GO:0007339) | 9.19162641 |
4 | organic cation transport (GO:0015695) | 9.12614898 |
5 | cell-cell recognition (GO:0009988) | 9.10646993 |
6 | synaptonemal complex assembly (GO:0007130) | 8.64899857 |
7 | spermatid development (GO:0007286) | 8.46719247 |
8 | synaptonemal complex organization (GO:0070193) | 8.44380015 |
9 | plasma membrane fusion (GO:0045026) | 8.40702492 |
10 | epithelial cilium movement (GO:0003351) | 8.14333615 |
11 | axonemal dynein complex assembly (GO:0070286) | 8.11842715 |
12 | reproduction (GO:0000003) | 7.91253476 |
13 | male meiosis (GO:0007140) | 7.86210286 |
14 | cilium or flagellum-dependent cell motility (GO:0001539) | 7.69668974 |
15 | regulation of cilium movement (GO:0003352) | 7.37954427 |
16 | motile cilium assembly (GO:0044458) | 7.29364830 |
17 | cilium movement (GO:0003341) | 6.71118264 |
18 | sperm capacitation (GO:0048240) | 6.59769420 |
19 | DNA methylation involved in gamete generation (GO:0043046) | 6.44573836 |
20 | single fertilization (GO:0007338) | 6.29665745 |
21 | spermatogenesis (GO:0007283) | 6.12861593 |
22 | male gamete generation (GO:0048232) | 6.10829366 |
23 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 6.06222589 |
24 | chromosome organization involved in meiosis (GO:0070192) | 5.78791060 |
25 | fertilization (GO:0009566) | 5.61336032 |
26 | gamete generation (GO:0007276) | 5.61233349 |
27 | negative regulation of inclusion body assembly (GO:0090084) | 5.54757443 |
28 | male meiosis I (GO:0007141) | 5.32710505 |
29 | meiotic nuclear division (GO:0007126) | 5.26147207 |
30 | germ cell development (GO:0007281) | 5.14819199 |
31 | microtubule depolymerization (GO:0007019) | 5.02659640 |
32 | cellular process involved in reproduction in multicellular organism (GO:0022412) | 5.01674846 |
33 | calcium ion-dependent exocytosis (GO:0017156) | 4.88331298 |
34 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.74221954 |
35 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.74221954 |
36 | quaternary ammonium group transport (GO:0015697) | 4.73462194 |
37 | carnitine transport (GO:0015879) | 4.67491804 |
38 | amino-acid betaine transport (GO:0015838) | 4.67491804 |
39 | purine nucleotide salvage (GO:0032261) | 4.59921883 |
40 | regulation of microtubule-based movement (GO:0060632) | 4.59586256 |
41 | drug transmembrane transport (GO:0006855) | 4.59006797 |
42 | regulation of inclusion body assembly (GO:0090083) | 4.51016332 |
43 | chromosome condensation (GO:0030261) | 4.38937891 |
44 | multicellular organismal reproductive process (GO:0048609) | 4.38500662 |
45 | negative regulation of acute inflammatory response (GO:0002674) | 4.34042076 |
46 | adenosine metabolic process (GO:0046085) | 4.28669408 |
47 | meiosis I (GO:0007127) | 4.27579403 |
48 | rRNA modification (GO:0000154) | 4.26509187 |
49 | DNA packaging (GO:0006323) | 4.24339140 |
50 | ventricular system development (GO:0021591) | 4.23928471 |
51 | cell recognition (GO:0008037) | 4.17901967 |
52 | microtubule severing (GO:0051013) | 4.10019059 |
53 | spermatid nucleus differentiation (GO:0007289) | 4.07827524 |
54 | regulation of plasminogen activation (GO:0010755) | 3.99165362 |
55 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.96172571 |
56 | glycerol ether metabolic process (GO:0006662) | 3.93930606 |
57 | sulfur amino acid catabolic process (GO:0000098) | 3.88091317 |
58 | mitochondrial RNA metabolic process (GO:0000959) | 3.87683519 |
59 | proteasome assembly (GO:0043248) | 3.84910409 |
60 | drug transport (GO:0015893) | 3.84051515 |
61 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.83774342 |
62 | urate metabolic process (GO:0046415) | 3.77922495 |
63 | protein complex biogenesis (GO:0070271) | 3.76294279 |
64 | branched-chain amino acid catabolic process (GO:0009083) | 3.74827896 |
65 | carnitine transmembrane transport (GO:1902603) | 3.73200998 |
66 | polyol catabolic process (GO:0046174) | 3.70885810 |
67 | NADH dehydrogenase complex assembly (GO:0010257) | 3.69141566 |
68 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.69141566 |
69 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.69141566 |
70 | ether metabolic process (GO:0018904) | 3.61577539 |
71 | response to mercury ion (GO:0046689) | 3.60316818 |
72 | aminoglycoside antibiotic metabolic process (GO:0030647) | 3.59348419 |
73 | pseudouridine synthesis (GO:0001522) | 3.59272703 |
74 | seminiferous tubule development (GO:0072520) | 3.58715291 |
75 | nucleoside transmembrane transport (GO:1901642) | 3.57399065 |
76 | left/right pattern formation (GO:0060972) | 3.54743069 |
77 | transcription from mitochondrial promoter (GO:0006390) | 3.52260982 |
78 | rRNA methylation (GO:0031167) | 3.51943018 |
79 | homocysteine metabolic process (GO:0050667) | 3.49259251 |
80 | cysteine metabolic process (GO:0006534) | 3.48015550 |
81 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.46337425 |
82 | multicellular organismal development (GO:0007275) | 3.45946604 |
83 | mannosylation (GO:0097502) | 3.42949282 |
84 | regulation of meiosis I (GO:0060631) | 3.42945154 |
85 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.42438072 |
86 | aldehyde catabolic process (GO:0046185) | 3.41357961 |
87 | regulation of spindle checkpoint (GO:0090231) | 3.40425285 |
88 | platelet dense granule organization (GO:0060155) | 3.38856114 |
89 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.37257318 |
90 | ATP synthesis coupled proton transport (GO:0015986) | 3.37257318 |
91 | meiotic cell cycle process (GO:1903046) | 3.37112309 |
92 | nitric oxide mediated signal transduction (GO:0007263) | 3.34117473 |
93 | regulation of hexokinase activity (GO:1903299) | 3.33902809 |
94 | regulation of glucokinase activity (GO:0033131) | 3.33902809 |
95 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.26363564 |
96 | cellular ketone body metabolic process (GO:0046950) | 3.24960884 |
97 | chaperone-mediated protein complex assembly (GO:0051131) | 3.24575793 |
98 | protein polyglutamylation (GO:0018095) | 3.21808806 |
99 | genitalia morphogenesis (GO:0035112) | 3.19939566 |
100 | gene silencing by RNA (GO:0031047) | 3.19576581 |
101 | fat-soluble vitamin catabolic process (GO:0042363) | 3.19481776 |
102 | vitamin catabolic process (GO:0009111) | 3.19481776 |
103 | protein-cofactor linkage (GO:0018065) | 3.18095387 |
104 | synapsis (GO:0007129) | 3.17425615 |
105 | fat-soluble vitamin biosynthetic process (GO:0042362) | 3.17411157 |
106 | branched-chain amino acid metabolic process (GO:0009081) | 3.16876902 |
107 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.16866182 |
108 | meiotic cell cycle (GO:0051321) | 3.15221783 |
109 | xenobiotic catabolic process (GO:0042178) | 3.14946883 |
110 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.13150337 |
111 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.11568666 |
112 | L-phenylalanine catabolic process (GO:0006559) | 3.11568666 |
113 | alditol metabolic process (GO:0019400) | 3.10743237 |
114 | purine-containing compound salvage (GO:0043101) | 3.10323119 |
115 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.07861747 |
116 | carnitine metabolic process (GO:0009437) | 3.07841814 |
117 | polyketide metabolic process (GO:0030638) | 3.06352405 |
118 | doxorubicin metabolic process (GO:0044598) | 3.06352405 |
119 | daunorubicin metabolic process (GO:0044597) | 3.06352405 |
120 | fructose metabolic process (GO:0006000) | 3.04171861 |
121 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.03953820 |
122 | regulation of mitochondrial translation (GO:0070129) | 3.03208701 |
123 | sexual reproduction (GO:0019953) | 3.02123226 |
124 | microtubule polymerization or depolymerization (GO:0031109) | 3.00937339 |
125 | single strand break repair (GO:0000012) | 3.00889422 |
126 | protein deneddylation (GO:0000338) | 3.00482532 |
127 | excretion (GO:0007588) | 3.00052117 |
128 | cullin deneddylation (GO:0010388) | 3.00016577 |
129 | vitamin D metabolic process (GO:0042359) | 2.99782617 |
130 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.99077605 |
131 | L-phenylalanine metabolic process (GO:0006558) | 2.99077605 |
132 | GMP metabolic process (GO:0046037) | 2.99022500 |
133 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.98031348 |
134 | nucleotide salvage (GO:0043173) | 2.97662935 |
135 | short-chain fatty acid metabolic process (GO:0046459) | 2.95739289 |
136 | respiratory chain complex IV assembly (GO:0008535) | 2.94994237 |
137 | polyol transport (GO:0015791) | 2.93227332 |
138 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.92166601 |
139 | lactate metabolic process (GO:0006089) | 2.90636056 |
140 | L-methionine salvage (GO:0071267) | 2.90151467 |
141 | L-methionine biosynthetic process (GO:0071265) | 2.90151467 |
142 | amino acid salvage (GO:0043102) | 2.90151467 |
143 | protein localization to cilium (GO:0061512) | 2.89861406 |
144 | electron transport chain (GO:0022900) | 2.89542533 |
145 | ketone body metabolic process (GO:1902224) | 2.89507224 |
146 | respiratory electron transport chain (GO:0022904) | 2.88964280 |
147 | lysine catabolic process (GO:0006554) | 2.88504340 |
148 | lysine metabolic process (GO:0006553) | 2.88504340 |
149 | GPI anchor biosynthetic process (GO:0006506) | 2.88077488 |
150 | positive regulation of glycolytic process (GO:0045821) | 2.86729569 |
151 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.86322367 |
152 | S-adenosylmethionine metabolic process (GO:0046500) | 2.85548646 |
153 | phosphate ion transport (GO:0006817) | 2.85343778 |
154 | C-terminal protein lipidation (GO:0006501) | 2.84495680 |
155 | endocrine pancreas development (GO:0031018) | 2.82464468 |
156 | positive regulation of prostaglandin secretion (GO:0032308) | 2.81716570 |
157 | histamine secretion (GO:0001821) | 2.79259228 |
158 | aggressive behavior (GO:0002118) | 2.75537901 |
159 | DNA deamination (GO:0045006) | 2.75363398 |
160 | amino-acid betaine metabolic process (GO:0006577) | 2.75032896 |
161 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.74136911 |
162 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.73250909 |
163 | GTP biosynthetic process (GO:0006183) | 2.72891152 |
164 | DNA ligation (GO:0006266) | 2.70269218 |
165 | cytochrome complex assembly (GO:0017004) | 2.69164339 |
166 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.68797402 |
167 | glycerol metabolic process (GO:0006071) | 2.68669422 |
168 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.68496480 |
169 | GPI anchor metabolic process (GO:0006505) | 2.67799224 |
170 | tetrahydrofolate metabolic process (GO:0046653) | 2.67641713 |
171 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.67311013 |
172 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.67311013 |
173 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.67311013 |
174 | protein K11-linked deubiquitination (GO:0035871) | 2.66761810 |
175 | inner mitochondrial membrane organization (GO:0007007) | 2.66470253 |
176 | sex differentiation (GO:0007548) | 2.64336112 |
177 | protein refolding (GO:0042026) | 2.63769071 |
178 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.63272382 |
179 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.63272382 |
180 | aspartate family amino acid catabolic process (GO:0009068) | 2.63222703 |
181 | histamine transport (GO:0051608) | 2.63112969 |
182 | glycoside metabolic process (GO:0016137) | 2.62727674 |
183 | aromatic amino acid family catabolic process (GO:0009074) | 2.62131600 |
184 | serine family amino acid catabolic process (GO:0009071) | 2.62001648 |
185 | gene silencing (GO:0016458) | 2.61315044 |
186 | oxidative phosphorylation (GO:0006119) | 2.59707359 |
187 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.59237832 |
188 | galactose catabolic process (GO:0019388) | 2.59178506 |
189 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.58400826 |
190 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.58400826 |
191 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.56562643 |
192 | sperm motility (GO:0030317) | 11.8616265 |
193 | cell wall macromolecule catabolic process (GO:0016998) | 11.2160757 |
194 | cell wall macromolecule metabolic process (GO:0044036) | 11.2160757 |
195 | fusion of sperm to egg plasma membrane (GO:0007342) | 11.1439662 |
196 | acrosome assembly (GO:0001675) | 10.2404500 |
197 | sperm-egg recognition (GO:0035036) | 10.1908208 |
198 | acrosome reaction (GO:0007340) | 10.1262329 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 9.50497734 |
2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 8.02026491 |
3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.45937283 |
4 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.06610031 |
5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.97984103 |
6 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 3.52809008 |
7 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.45833101 |
8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.23845403 |
9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.12572918 |
10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.12568581 |
11 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.96195565 |
12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.84013509 |
13 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.81000769 |
14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.78467312 |
15 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.65306479 |
16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.64686697 |
17 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.60138473 |
18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.56304876 |
19 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.46468509 |
20 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.30347792 |
21 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.26913969 |
22 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 2.26094822 |
23 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.12292135 |
24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.11654696 |
25 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 2.07864942 |
26 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 2.07313751 |
27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.05861481 |
28 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.99634265 |
29 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.99414809 |
30 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.98543838 |
31 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.98520261 |
32 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.97862742 |
33 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.87191690 |
34 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.85347895 |
35 | STAT1_17558387_ChIP-Seq_HELA_Human | 1.83396558 |
36 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.81281798 |
37 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.77954120 |
38 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.77924765 |
39 | * HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.75462729 |
40 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.74250599 |
41 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.74212092 |
42 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.72794255 |
43 | FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.72009021 |
44 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.71142459 |
45 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.68982014 |
46 | GATA3_21867929_ChIP-Seq_CD8_Mouse | 1.65996967 |
47 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 1.63379535 |
48 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.61399516 |
49 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.60509573 |
50 | AR_20517297_ChIP-Seq_VCAP_Human | 1.59654294 |
51 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.56947405 |
52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.56128146 |
53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.56128146 |
54 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.56005606 |
55 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.53087167 |
56 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.52091831 |
57 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.51897682 |
58 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.50911927 |
59 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.49807312 |
60 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.49099127 |
61 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.49099127 |
62 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.48602441 |
63 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.47786206 |
64 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.47665972 |
65 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 1.46164609 |
66 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.45556827 |
67 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.44537337 |
68 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.42251069 |
69 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.39676881 |
70 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.37989691 |
71 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.37865932 |
72 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 1.37773404 |
73 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.35826101 |
74 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.32918828 |
75 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.32914687 |
76 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.32908781 |
77 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 1.32374706 |
78 | EWS_26573619_Chip-Seq_HEK293_Human | 1.31290323 |
79 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.30306887 |
80 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.29563797 |
81 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.28800150 |
82 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.28568118 |
83 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.28220817 |
84 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.28010009 |
85 | KDM2B_26808549_Chip-Seq_REH_Human | 1.27784932 |
86 | FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.27655839 |
87 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.27107023 |
88 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.26050878 |
89 | * FUS_26573619_Chip-Seq_HEK293_Human | 1.25815676 |
90 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 1.24587365 |
91 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.24483663 |
92 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.22830988 |
93 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.20281220 |
94 | CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.20159716 |
95 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.20020846 |
96 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.19869415 |
97 | * RNF2_27304074_Chip-Seq_NSC_Mouse | 1.19245834 |
98 | GF1_26923725_Chip-Seq_HPCs_Mouse | 1.19212737 |
99 | * CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.18648425 |
100 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.18326252 |
101 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 1.18115424 |
102 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.17683868 |
103 | SOX11_22085726_ChIP-Seq_ESNs_Mouse | 1.16947030 |
104 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.16614443 |
105 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.16568848 |
106 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.16562019 |
107 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.16516249 |
108 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.16306158 |
109 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.15950548 |
110 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.15299036 |
111 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.15073137 |
112 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.14399781 |
113 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.14166432 |
114 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.13617863 |
115 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.13295097 |
116 | NCOR_22424771_ChIP-Seq_293T_Human | 1.13225926 |
117 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 1.13002154 |
118 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.12920393 |
119 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.11097942 |
120 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.10285841 |
121 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.09233820 |
122 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.08933800 |
123 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.08933800 |
124 | LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.08582904 |
125 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.08447941 |
126 | NFYB_21822215_ChIP-Seq_K562_Human | 1.07105830 |
127 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.06452582 |
128 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.06412231 |
129 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.05974550 |
130 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.04303860 |
131 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.03893825 |
132 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.01598891 |
133 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 1.01151356 |
134 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.01028503 |
135 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 1.00963564 |
136 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.00268583 |
137 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.99620955 |
138 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.99335081 |
139 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.99133988 |
140 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.99103235 |
141 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.98061156 |
142 | GF1B_26923725_Chip-Seq_HPCs_Mouse | 0.98056973 |
143 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97388442 |
144 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.97019273 |
145 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96691061 |
146 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.96657011 |
147 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.96473143 |
148 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.96355677 |
149 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.95824815 |
150 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.95227606 |
151 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.95225926 |
152 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.95125639 |
153 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.94574585 |
154 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.94170044 |
155 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.94155590 |
156 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.93282122 |
157 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.93237523 |
158 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.93038746 |
159 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.92374197 |
160 | FLI1_21867929_ChIP-Seq_CD8_Mouse | 0.92246792 |
161 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.91678699 |
162 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.91500658 |
163 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.90504377 |
164 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.89528436 |
165 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.89429200 |
166 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.89043050 |
167 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.88968785 |
168 | * FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.88835588 |
169 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.88654555 |
170 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.87911687 |
171 | NFYA_21822215_ChIP-Seq_K562_Human | 0.87686737 |
172 | TBL1_22424771_ChIP-Seq_293T_Human | 0.87328848 |
173 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.87002796 |
174 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.86860030 |
175 | AR_25329375_ChIP-Seq_VCAP_Human | 0.86090367 |
176 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.85635275 |
177 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.85601952 |
178 | P300_19829295_ChIP-Seq_ESCs_Human | 0.85014449 |
179 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.84890879 |
180 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.84173098 |
181 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.84087168 |
182 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.83105393 |
183 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.82780933 |
184 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.82090070 |
185 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.81559664 |
186 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.81359714 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003698_abnormal_male_reproductive | 5.18539963 |
2 | MP0001929_abnormal_gametogenesis | 4.95565316 |
3 | MP0008877_abnormal_DNA_methylation | 4.92401643 |
4 | MP0004043_abnormal_pH_regulation | 3.68281369 |
5 | MP0002210_abnormal_sex_determination | 3.46653294 |
6 | MP0005646_abnormal_pituitary_gland | 3.35344571 |
7 | MP0005360_urolithiasis | 3.11659092 |
8 | MP0001145_abnormal_male_reproductive | 3.01350239 |
9 | MP0000013_abnormal_adipose_tissue | 2.96725217 |
10 | MP0002161_abnormal_fertility/fecundity | 2.87573179 |
11 | MP0009697_abnormal_copulation | 2.81499764 |
12 | MP0001765_abnormal_ion_homeostasis | 2.81371701 |
13 | MP0002139_abnormal_hepatobiliary_system | 2.73342541 |
14 | MP0004147_increased_porphyrin_level | 2.69840393 |
15 | MP0000653_abnormal_sex_gland | 2.62522220 |
16 | MP0005645_abnormal_hypothalamus_physiol | 2.48841873 |
17 | MP0003787_abnormal_imprinting | 2.45618197 |
18 | MP0005670_abnormal_white_adipose | 2.39017178 |
19 | MP0003195_calcinosis | 2.38895050 |
20 | MP0002653_abnormal_ependyma_morphology | 2.29852492 |
21 | MP0010386_abnormal_urinary_bladder | 2.29190337 |
22 | MP0002938_white_spotting | 2.20022939 |
23 | MP0004019_abnormal_vitamin_homeostasis | 2.18170135 |
24 | MP0005084_abnormal_gallbladder_morpholo | 2.15516583 |
25 | MP0003646_muscle_fatigue | 2.12132312 |
26 | MP0008995_early_reproductive_senescence | 2.08561114 |
27 | MP0000516_abnormal_urinary_system | 2.05255686 |
28 | MP0005367_renal/urinary_system_phenotyp | 2.05255686 |
29 | MP0008872_abnormal_physiological_respon | 2.03911352 |
30 | MP0005636_abnormal_mineral_homeostasis | 2.02330056 |
31 | MP0005410_abnormal_fertilization | 12.7885922 |
32 | MP0005332_abnormal_amino_acid | 1.98591160 |
33 | MP0005075_abnormal_melanosome_morpholog | 1.97301301 |
34 | MP0009643_abnormal_urine_homeostasis | 1.83836844 |
35 | MP0005377_hearing/vestibular/ear_phenot | 1.83371891 |
36 | MP0003878_abnormal_ear_physiology | 1.83371891 |
37 | MP0005220_abnormal_exocrine_pancreas | 1.82524577 |
38 | MP0009780_abnormal_chondrocyte_physiolo | 1.71737022 |
39 | MP0002132_abnormal_respiratory_system | 1.65236764 |
40 | MP0001756_abnormal_urination | 1.44218895 |
41 | MP0002138_abnormal_hepatobiliary_system | 1.42066812 |
42 | MP0006072_abnormal_retinal_apoptosis | 1.39894383 |
43 | MP0002736_abnormal_nociception_after | 1.39701846 |
44 | MP0002095_abnormal_skin_pigmentation | 1.37537507 |
45 | MP0003123_paternal_imprinting | 1.36784792 |
46 | MP0002160_abnormal_reproductive_system | 1.34205365 |
47 | MP0002282_abnormal_trachea_morphology | 1.32614116 |
48 | MP0000372_irregular_coat_pigmentation | 1.32609337 |
49 | MP0002166_altered_tumor_susceptibility | 1.31294362 |
50 | MP0002136_abnormal_kidney_physiology | 1.30060085 |
51 | MP0005551_abnormal_eye_electrophysiolog | 1.29039052 |
52 | MP0002006_tumorigenesis | 1.28867878 |
53 | MP0002396_abnormal_hematopoietic_system | 1.26969733 |
54 | MP0000678_abnormal_parathyroid_gland | 1.26282783 |
55 | MP0003121_genomic_imprinting | 1.22507857 |
56 | MP0001905_abnormal_dopamine_level | 1.17476036 |
57 | MP0008058_abnormal_DNA_repair | 1.16400741 |
58 | MP0005623_abnormal_meninges_morphology | 1.15250574 |
59 | MP0003786_premature_aging | 1.13146972 |
60 | MP0003718_maternal_effect | 1.12812614 |
61 | MP0003283_abnormal_digestive_organ | 1.11844093 |
62 | MP0008875_abnormal_xenobiotic_pharmacok | 1.08882544 |
63 | MP0003122_maternal_imprinting | 1.08392904 |
64 | MP0008775_abnormal_heart_ventricle | 1.05903683 |
65 | MP0000003_abnormal_adipose_tissue | 1.05671230 |
66 | MP0006036_abnormal_mitochondrial_physio | 1.05604009 |
67 | MP0004233_abnormal_muscle_weight | 1.03998889 |
68 | MP0003183_abnormal_peptide_metabolism | 1.03374594 |
69 | MP0005266_abnormal_metabolism | 1.02478168 |
70 | MP0002277_abnormal_respiratory_mucosa | 0.99383768 |
71 | MP0005376_homeostasis/metabolism_phenot | 0.95960461 |
72 | MP0002928_abnormal_bile_duct | 0.90884668 |
73 | MP0006276_abnormal_autonomic_nervous | 0.88316560 |
74 | MP0001968_abnormal_touch/_nociception | 0.85550444 |
75 | MP0008961_abnormal_basal_metabolism | 0.85311345 |
76 | MP0005647_abnormal_sex_gland | 0.84668502 |
77 | MP0001919_abnormal_reproductive_system | 0.81976782 |
78 | MP0003656_abnormal_erythrocyte_physiolo | 0.81439603 |
79 | MP0002102_abnormal_ear_morphology | 0.79517739 |
80 | MP0003252_abnormal_bile_duct | 0.79203765 |
81 | MP0005408_hypopigmentation | 0.78127249 |
82 | MP0005365_abnormal_bile_salt | 0.77176195 |
83 | MP0005253_abnormal_eye_physiology | 0.77056468 |
84 | MP0005083_abnormal_biliary_tract | 0.75658007 |
85 | MP0002638_abnormal_pupillary_reflex | 0.74127359 |
86 | MP0003315_abnormal_perineum_morphology | 0.73621920 |
87 | MP0005319_abnormal_enzyme/_coenzyme | 0.73342572 |
88 | MP0000371_diluted_coat_color | 0.73254352 |
89 | MP0002896_abnormal_bone_mineralization | 0.73133916 |
90 | MP0001764_abnormal_homeostasis | 0.73080782 |
91 | MP0005167_abnormal_blood-brain_barrier | 0.71894033 |
92 | MP0005379_endocrine/exocrine_gland_phen | 0.71517928 |
93 | MP0005666_abnormal_adipose_tissue | 0.70300752 |
94 | MP0005330_cardiomyopathy | 0.69381896 |
95 | MP0010329_abnormal_lipoprotein_level | 0.69334192 |
96 | MP0005464_abnormal_platelet_physiology | 0.67759187 |
97 | MP0004145_abnormal_muscle_electrophysio | 0.67170399 |
98 | MP0002796_impaired_skin_barrier | 0.63914019 |
99 | MP0001119_abnormal_female_reproductive | 0.63321469 |
100 | MP0003186_abnormal_redox_activity | 0.63017730 |
101 | MP0001958_emphysema | 0.59551906 |
102 | MP0010094_abnormal_chromosome_stability | 0.58334725 |
103 | MP0003879_abnormal_hair_cell | 0.57924374 |
104 | MP0005389_reproductive_system_phenotype | 0.57331765 |
105 | MP0000358_abnormal_cell_content/ | 0.56098000 |
106 | MP0003699_abnormal_female_reproductive | 0.55285372 |
107 | MP0002234_abnormal_pharynx_morphology | 0.55185541 |
108 | MP0000538_abnormal_urinary_bladder | 0.54715811 |
109 | MP0005085_abnormal_gallbladder_physiolo | 0.54277956 |
110 | MP0000534_abnormal_ureter_morphology | 0.54078681 |
111 | MP0004885_abnormal_endolymph | 0.53221812 |
112 | MP0002168_other_aberrant_phenotype | 0.53001239 |
113 | MP0002115_abnormal_skeleton_extremities | 0.52917577 |
114 | MP0005535_abnormal_body_temperature | 0.50707955 |
115 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.50517911 |
116 | MP0001293_anophthalmia | 0.48467040 |
117 | MP0006035_abnormal_mitochondrial_morpho | 0.48122083 |
118 | MP0009046_muscle_twitch | 0.46829144 |
119 | MP0001270_distended_abdomen | 0.45235039 |
120 | MP0002135_abnormal_kidney_morphology | 0.44488707 |
121 | MP0001661_extended_life_span | 0.42457391 |
122 | MP0002876_abnormal_thyroid_physiology | 0.41795026 |
123 | MP0003115_abnormal_respiratory_system | 0.41412625 |
124 | MP0001324_abnormal_eye_pigmentation | 0.40830900 |
125 | MP0004134_abnormal_chest_morphology | 0.40117751 |
126 | MP0009672_abnormal_birth_weight | 0.39440230 |
127 | MP0001984_abnormal_olfaction | 0.39065111 |
128 | MP0002269_muscular_atrophy | 0.37589218 |
129 | MP0009642_abnormal_blood_homeostasis | 0.37192319 |
130 | MP0003953_abnormal_hormone_level | 0.36895349 |
131 | MP0000163_abnormal_cartilage_morphology | 0.36467108 |
132 | MP0000230_abnormal_systemic_arterial | 0.35396608 |
133 | MP0003959_abnormal_lean_body | 0.35386790 |
134 | MP0002118_abnormal_lipid_homeostasis | 0.35214647 |
135 | MP0001944_abnormal_pancreas_morphology | 0.34597869 |
136 | MP0002837_dystrophic_cardiac_calcinosis | 0.34074645 |
137 | MP0004264_abnormal_extraembryonic_tissu | 0.30796268 |
138 | MP0001727_abnormal_embryo_implantation | 0.30632459 |
139 | MP0003806_abnormal_nucleotide_metabolis | 0.29121228 |
140 | MP0001730_embryonic_growth_arrest | 0.29081079 |
141 | MP0004742_abnormal_vestibular_system | 0.28875848 |
142 | MP0003942_abnormal_urinary_system | 0.27564638 |
143 | MP0003795_abnormal_bone_structure | 0.27374478 |
144 | MP0004036_abnormal_muscle_relaxation | 0.26117244 |
145 | MP0002909_abnormal_adrenal_gland | 0.25923520 |
146 | MP0002109_abnormal_limb_morphology | 0.24356495 |
147 | MP0002078_abnormal_glucose_homeostasis | 0.24286707 |
148 | MP0002089_abnormal_postnatal_growth/wei | 0.24004755 |
149 | MP0001986_abnormal_taste_sensitivity | 0.23445073 |
150 | MP0005058_abnormal_lysosome_morphology | 0.22868274 |
151 | MP0002693_abnormal_pancreas_physiology | 0.22149541 |
152 | MP0009703_decreased_birth_body | 0.21971861 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 9.78438172 |
2 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 9.34132276 |
3 | Absent/shortened dynein arms (HP:0200106) | 9.34132276 |
4 | Abnormal respiratory motile cilium physiology (HP:0012261) | 6.75054356 |
5 | Abnormal respiratory epithelium morphology (HP:0012253) | 6.25529035 |
6 | Abnormal respiratory motile cilium morphology (HP:0005938) | 6.25529035 |
7 | Abnormality of alanine metabolism (HP:0010916) | 5.91037812 |
8 | Hyperalaninemia (HP:0003348) | 5.91037812 |
9 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 5.91037812 |
10 | Chronic bronchitis (HP:0004469) | 5.78110906 |
11 | Polydipsia (HP:0001959) | 5.60115786 |
12 | Abnormal drinking behavior (HP:0030082) | 5.60115786 |
13 | Polyuria (HP:0000103) | 5.52956930 |
14 | Abnormal urine output (HP:0012590) | 5.34590355 |
15 | Rhinitis (HP:0012384) | 5.33557993 |
16 | Abnormal ciliary motility (HP:0012262) | 5.22576651 |
17 | Abnormality of renal excretion (HP:0011036) | 5.19891292 |
18 | Infertility (HP:0000789) | 4.91785495 |
19 | Hypoglycemic seizures (HP:0002173) | 4.56743367 |
20 | Ketoacidosis (HP:0001993) | 4.52819711 |
21 | Hypokalemic alkalosis (HP:0001949) | 4.40987321 |
22 | Nasal polyposis (HP:0100582) | 4.36777904 |
23 | Tubular atrophy (HP:0000092) | 4.24282300 |
24 | Metabolic alkalosis (HP:0200114) | 4.22053794 |
25 | Delayed epiphyseal ossification (HP:0002663) | 4.20038069 |
26 | Hypoglycemic coma (HP:0001325) | 4.18682800 |
27 | Hyperinsulinemic hypoglycemia (HP:0000825) | 4.16933704 |
28 | Abnormal spermatogenesis (HP:0008669) | 4.08098682 |
29 | Increased circulating renin level (HP:0000848) | 4.03277684 |
30 | Abnormality of chloride homeostasis (HP:0011422) | 4.00207438 |
31 | Hypomagnesemia (HP:0002917) | 3.99460879 |
32 | Constricted visual fields (HP:0001133) | 3.84348089 |
33 | Symptomatic seizures (HP:0011145) | 3.69290888 |
34 | Nephronophthisis (HP:0000090) | 3.67306070 |
35 | Generalized aminoaciduria (HP:0002909) | 3.66105704 |
36 | Hyperactive renin-angiotensin system (HP:0000841) | 3.63619808 |
37 | Gout (HP:0001997) | 3.62669535 |
38 | Tubulointerstitial fibrosis (HP:0005576) | 3.58168833 |
39 | Hepatic necrosis (HP:0002605) | 3.56825512 |
40 | Abnormality of the nasal mucosa (HP:0000433) | 3.55495142 |
41 | Azoospermia (HP:0000027) | 3.44710633 |
42 | Abnormality of the renal medulla (HP:0100957) | 3.42243641 |
43 | Bronchitis (HP:0012387) | 3.41939853 |
44 | Male infertility (HP:0003251) | 3.41823212 |
45 | Acute necrotizing encephalopathy (HP:0006965) | 3.41744291 |
46 | Abnormality of magnesium homeostasis (HP:0004921) | 3.30458164 |
47 | Mitochondrial inheritance (HP:0001427) | 3.27817924 |
48 | Progressive macrocephaly (HP:0004481) | 3.18530370 |
49 | Bronchiectasis (HP:0002110) | 3.16292020 |
50 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.15688425 |
51 | Tubulointerstitial abnormality (HP:0001969) | 3.15230687 |
52 | Increased CSF lactate (HP:0002490) | 3.12604545 |
53 | Acute encephalopathy (HP:0006846) | 3.09473198 |
54 | Hyperglycemia (HP:0003074) | 3.03664872 |
55 | Abnormality of endocrine pancreas physiology (HP:0012093) | 3.01628713 |
56 | Abnormality of the pancreatic islet cells (HP:0006476) | 3.01628713 |
57 | Hepatocellular necrosis (HP:0001404) | 3.01298962 |
58 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.00938509 |
59 | Large for gestational age (HP:0001520) | 3.00425511 |
60 | Cerebral edema (HP:0002181) | 2.98334608 |
61 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.97952291 |
62 | Proximal tubulopathy (HP:0000114) | 2.93087225 |
63 | Widely patent fontanelles and sutures (HP:0004492) | 2.91665039 |
64 | Tetany (HP:0001281) | 2.90953554 |
65 | Testicular atrophy (HP:0000029) | 2.86081828 |
66 | Renal salt wasting (HP:0000127) | 2.82622214 |
67 | Hyperuricemia (HP:0002149) | 2.81665319 |
68 | Increased purine levels (HP:0004368) | 2.81665319 |
69 | Increased serum lactate (HP:0002151) | 2.81628559 |
70 | 3-Methylglutaconic aciduria (HP:0003535) | 2.80550798 |
71 | Abnormality of serum amino acid levels (HP:0003112) | 2.75412022 |
72 | Lactic acidosis (HP:0003128) | 2.69824060 |
73 | Reduced antithrombin III activity (HP:0001976) | 2.68316639 |
74 | Alkalosis (HP:0001948) | 2.67452657 |
75 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.66057859 |
76 | Abnormality of the renal cortex (HP:0011035) | 2.65694317 |
77 | Increased hepatocellular lipid droplets (HP:0006565) | 2.63489706 |
78 | Conjugated hyperbilirubinemia (HP:0002908) | 2.61064918 |
79 | Lethargy (HP:0001254) | 2.60839904 |
80 | Protuberant abdomen (HP:0001538) | 2.57564674 |
81 | Abnormality of renin-angiotensin system (HP:0000847) | 2.53951984 |
82 | Lipid accumulation in hepatocytes (HP:0006561) | 2.50900390 |
83 | Hyperaldosteronism (HP:0000859) | 2.50367690 |
84 | Hypothermia (HP:0002045) | 2.50120525 |
85 | Type I transferrin isoform profile (HP:0003642) | 2.47962015 |
86 | Hyperammonemia (HP:0001987) | 2.43865931 |
87 | Abnormality of methionine metabolism (HP:0010901) | 2.41741207 |
88 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.41284251 |
89 | Dicarboxylic aciduria (HP:0003215) | 2.41284251 |
90 | Patchy hypopigmentation of hair (HP:0011365) | 2.33606016 |
91 | Metaphyseal cupping (HP:0003021) | 2.32908731 |
92 | Epiphyseal dysplasia (HP:0002656) | 2.29014431 |
93 | Hyperphosphaturia (HP:0003109) | 2.28571212 |
94 | Attenuation of retinal blood vessels (HP:0007843) | 2.27476444 |
95 | Abnormality of purine metabolism (HP:0004352) | 2.26390963 |
96 | Recurrent otitis media (HP:0000403) | 2.24728946 |
97 | Increased intramyocellular lipid droplets (HP:0012240) | 2.24469198 |
98 | Abolished electroretinogram (ERG) (HP:0000550) | 2.23890453 |
99 | Enlarged epiphyses (HP:0010580) | 2.23126272 |
100 | Methylmalonic acidemia (HP:0002912) | 2.23103187 |
101 | Metaphyseal irregularity (HP:0003025) | 2.19533876 |
102 | Thin bony cortex (HP:0002753) | 2.18353168 |
103 | Congenital sensorineural hearing impairment (HP:0008527) | 2.17480673 |
104 | Hypercalciuria (HP:0002150) | 2.17137099 |
105 | Increased serum pyruvate (HP:0003542) | 2.15616255 |
106 | Metabolic acidosis (HP:0001942) | 2.14570319 |
107 | Stage 5 chronic kidney disease (HP:0003774) | 2.14448680 |
108 | Pancreatic fibrosis (HP:0100732) | 2.13939338 |
109 | True hermaphroditism (HP:0010459) | 2.12272866 |
110 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.11804284 |
111 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.11406620 |
112 | Abnormal protein glycosylation (HP:0012346) | 2.11036883 |
113 | Abnormal glycosylation (HP:0012345) | 2.11036883 |
114 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.11036883 |
115 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.11036883 |
116 | White forelock (HP:0002211) | 2.08696560 |
117 | Tubulointerstitial nephritis (HP:0001970) | 2.07993268 |
118 | Short ribs (HP:0000773) | 2.06606984 |
119 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.05825739 |
120 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.05752156 |
121 | Abnormality of the costochondral junction (HP:0000919) | 2.05728678 |
122 | Gonadotropin excess (HP:0000837) | 2.04904492 |
123 | Renal cortical cysts (HP:0000803) | 2.04874889 |
124 | Irregular epiphyses (HP:0010582) | 2.04458581 |
125 | Renal Fanconi syndrome (HP:0001994) | 2.03867182 |
126 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.03311454 |
127 | Hypokalemia (HP:0002900) | 2.02473956 |
128 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.01637180 |
129 | Vascular calcification (HP:0004934) | 2.01492933 |
130 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.98625929 |
131 | Recurrent sinusitis (HP:0011108) | 1.97893132 |
132 | Abnormality of potassium homeostasis (HP:0011042) | 1.96666633 |
133 | Prolonged partial thromboplastin time (HP:0003645) | 1.94687451 |
134 | Delayed CNS myelination (HP:0002188) | 1.93235188 |
135 | Pancreatic cysts (HP:0001737) | 1.92912043 |
136 | Nephrocalcinosis (HP:0000121) | 1.92063779 |
137 | Impulsivity (HP:0100710) | 1.90168092 |
138 | Respiratory failure (HP:0002878) | 1.88497833 |
139 | Methylmalonic aciduria (HP:0012120) | 1.88353854 |
140 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.88051316 |
141 | Myoglobinuria (HP:0002913) | 1.85695932 |
142 | Exercise intolerance (HP:0003546) | 1.85272802 |
143 | Recurrent bronchitis (HP:0002837) | 1.84492485 |
144 | Optic disc pallor (HP:0000543) | 1.82870493 |
145 | Increased muscle lipid content (HP:0009058) | 1.80378210 |
146 | Abnormality of glycolysis (HP:0004366) | 1.80259872 |
147 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.80126046 |
148 | Molar tooth sign on MRI (HP:0002419) | 1.79777202 |
149 | Abnormality of midbrain morphology (HP:0002418) | 1.79777202 |
150 | Hypobetalipoproteinemia (HP:0003563) | 1.79412928 |
151 | Fibular hypoplasia (HP:0003038) | 1.78695102 |
152 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.78333236 |
153 | Hyperglycinemia (HP:0002154) | 1.76867158 |
154 | Short thorax (HP:0010306) | 1.76538225 |
155 | Cardiovascular calcification (HP:0011915) | 1.76269263 |
156 | Vitreoretinal degeneration (HP:0000655) | 1.75987976 |
157 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.75771235 |
158 | Lower limb hyperreflexia (HP:0002395) | 1.75084179 |
159 | Vomiting (HP:0002013) | 1.74039718 |
160 | Abnormal urine phosphate concentration (HP:0012599) | 1.73867225 |
161 | Congenital stationary night blindness (HP:0007642) | 1.73591540 |
162 | Metaphyseal dysplasia (HP:0100255) | 1.73090687 |
163 | Severe visual impairment (HP:0001141) | 1.71417131 |
164 | CNS demyelination (HP:0007305) | 1.71065623 |
165 | Abnormality of nucleobase metabolism (HP:0010932) | 1.70031968 |
166 | Hypokinesia (HP:0002375) | 1.68144147 |
167 | Opisthotonus (HP:0002179) | 1.67480325 |
168 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.67161692 |
169 | Wide cranial sutures (HP:0010537) | 1.66989451 |
170 | Short femoral neck (HP:0100864) | 1.66365215 |
171 | Flattened epiphyses (HP:0003071) | 1.64798029 |
172 | Congenital hepatic fibrosis (HP:0002612) | 1.64072429 |
173 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.64015827 |
174 | Villous atrophy (HP:0011473) | 1.63781966 |
175 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.63781966 |
176 | Renal tubular acidosis (HP:0001947) | 1.61106189 |
177 | Facial cleft (HP:0002006) | 1.60735559 |
178 | Ketosis (HP:0001946) | 1.59312413 |
179 | Hyperkalemia (HP:0002153) | 1.52937522 |
180 | Medial flaring of the eyebrow (HP:0010747) | 1.52175419 |
181 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.50099803 |
182 | Hyperglycinuria (HP:0003108) | 1.49284900 |
183 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 1.47656336 |
184 | Postaxial foot polydactyly (HP:0001830) | 1.47073571 |
185 | Hypophosphatemia (HP:0002148) | 1.45874322 |
186 | Hand muscle atrophy (HP:0009130) | 1.45670948 |
187 | Abnormal tarsal ossification (HP:0008369) | 1.45363385 |
188 | Rickets (HP:0002748) | 1.45005073 |
189 | Abnormality of urine glucose concentration (HP:0011016) | 1.42131579 |
190 | Glycosuria (HP:0003076) | 1.42131579 |
191 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.41916118 |
192 | Carpal bone hypoplasia (HP:0001498) | 1.41715803 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PDK4 | 6.96232666 |
2 | PDK3 | 6.96232666 |
3 | TESK1 | 5.70798977 |
4 | WNK4 | 5.08266582 |
5 | PRKD3 | 4.82303391 |
6 | PDK2 | 4.66115273 |
7 | WNK3 | 3.41617714 |
8 | ICK | 3.34670476 |
9 | STK39 | 3.09840999 |
10 | SCYL2 | 3.04993864 |
11 | TAOK3 | 3.01322464 |
12 | OXSR1 | 2.58219543 |
13 | EIF2AK3 | 2.56515846 |
14 | ZAK | 2.54241799 |
15 | VRK2 | 2.53481819 |
16 | NUAK1 | 2.46854368 |
17 | PTK2B | 2.06886368 |
18 | STK38L | 2.01540060 |
19 | STK38 | 1.92164747 |
20 | RPS6KB2 | 1.89096787 |
21 | PBK | 1.81358720 |
22 | NEK2 | 1.73978043 |
23 | EIF2AK1 | 1.67498216 |
24 | MAP4K2 | 1.56704111 |
25 | NME2 | 1.52227629 |
26 | PHKG1 | 1.51880005 |
27 | PHKG2 | 1.51880005 |
28 | DYRK1B | 1.44602939 |
29 | TIE1 | 1.42881133 |
30 | ADRBK2 | 1.42267356 |
31 | LIMK1 | 1.41025830 |
32 | WNK1 | 1.36800687 |
33 | FER | 1.35451468 |
34 | KDR | 1.35350103 |
35 | GRK1 | 1.30356347 |
36 | MAP2K7 | 1.29968341 |
37 | BUB1 | 1.23474506 |
38 | FGFR2 | 1.22968962 |
39 | PIM2 | 1.16580504 |
40 | VRK1 | 1.16488089 |
41 | KIT | 1.11579275 |
42 | TLK1 | 1.11091173 |
43 | IRAK1 | 1.10280747 |
44 | CSNK1G3 | 1.10148167 |
45 | TRIM28 | 1.06833153 |
46 | NTRK3 | 1.06571731 |
47 | EPHA2 | 1.04508871 |
48 | MAP2K3 | 1.02157421 |
49 | PNCK | 1.01549900 |
50 | PDK1 | 0.99809252 |
51 | ABL2 | 0.98146222 |
52 | PINK1 | 0.97278228 |
53 | CSNK1G1 | 0.94585432 |
54 | PLK3 | 0.90929692 |
55 | MAPK15 | 0.89666609 |
56 | MAP3K3 | 0.89270077 |
57 | ADRBK1 | 0.87696768 |
58 | TNK2 | 0.84126129 |
59 | PASK | 0.83656689 |
60 | FLT3 | 0.82691919 |
61 | BCKDK | 0.82469152 |
62 | DAPK2 | 0.78012838 |
63 | IRAK2 | 0.77669338 |
64 | PDPK1 | 0.76923497 |
65 | TXK | 0.75842319 |
66 | DYRK3 | 0.72542792 |
67 | STK3 | 0.72423923 |
68 | CSNK1A1 | 0.71745346 |
69 | TTK | 0.69531181 |
70 | ACVR1B | 0.68132762 |
71 | MAPKAPK3 | 0.66895620 |
72 | IRAK4 | 0.66614440 |
73 | CSNK1A1L | 0.65336836 |
74 | TYRO3 | 0.64788169 |
75 | CSNK1G2 | 0.63647337 |
76 | JAK3 | 0.63264335 |
77 | MAP3K12 | 0.62630637 |
78 | PRKCE | 0.61642347 |
79 | DAPK1 | 0.60432381 |
80 | CHEK2 | 0.59316026 |
81 | INSRR | 0.59066949 |
82 | CDK9 | 0.58952020 |
83 | BRSK2 | 0.58916290 |
84 | CDK3 | 0.56455863 |
85 | TBK1 | 0.56199496 |
86 | DDR2 | 0.56058508 |
87 | NEK1 | 0.53252509 |
88 | TRPM7 | 0.51108025 |
89 | BCR | 0.49862432 |
90 | RPS6KA5 | 0.48861045 |
91 | CAMK2D | 0.48734631 |
92 | MAPKAPK5 | 0.48636528 |
93 | RPS6KA4 | 0.47309968 |
94 | SGK223 | 0.46356455 |
95 | SGK494 | 0.46356455 |
96 | CCNB1 | 0.45527937 |
97 | CDC7 | 0.45217153 |
98 | ILK | 0.42590323 |
99 | HIPK2 | 0.42017596 |
100 | CHEK1 | 0.40976099 |
101 | AURKB | 0.40146451 |
102 | NME1 | 0.37871367 |
103 | TAOK1 | 0.37128239 |
104 | MAP3K11 | 0.36319215 |
105 | PRKG2 | 0.35304321 |
106 | MST4 | 0.34331874 |
107 | WEE1 | 0.33741651 |
108 | FES | 0.32616778 |
109 | DYRK2 | 0.32030187 |
110 | IKBKB | 0.31902188 |
111 | PRKAA1 | 0.31682416 |
112 | CDK12 | 0.30364156 |
113 | LMTK2 | 0.27885711 |
114 | PAK4 | 0.27675051 |
115 | ATM | 0.27590560 |
116 | BRSK1 | 0.27546961 |
117 | ATR | 0.26315031 |
118 | PRKCG | 0.25522607 |
119 | RIPK4 | 0.24375429 |
120 | PLK1 | 0.24340062 |
121 | MTOR | 0.23852161 |
122 | MAP2K6 | 0.21253976 |
123 | CAMK1G | 0.19858245 |
124 | SIK2 | 0.19741855 |
125 | EPHB1 | 0.18552116 |
126 | GSK3A | 0.18479189 |
127 | PRKCZ | 0.17985185 |
128 | MUSK | 0.17505357 |
129 | NEK6 | 0.17425994 |
130 | STK24 | 0.17292166 |
131 | SGK2 | 0.17005360 |
132 | MARK3 | 0.16006615 |
133 | PAK1 | 0.15093588 |
134 | SGK3 | 0.14825356 |
135 | FRK | 0.13420538 |
136 | MST1R | 0.13391829 |
137 | PRKCD | 0.12036015 |
138 | MAPK11 | 0.11848833 |
139 | PRKACG | 0.11471214 |
140 | MAP3K4 | 0.10733503 |
141 | CDC42BPA | 0.08890023 |
142 | TESK2 | 0.08362707 |
143 | PLK4 | 0.08281300 |
144 | STK16 | 0.07934115 |
145 | SGK1 | 0.06274878 |
146 | PIM1 | 0.05893586 |
147 | MARK2 | 0.05250263 |
148 | CDK1 | 0.04430435 |
149 | STK10 | 0.04318441 |
150 | CSNK2A1 | 0.04317049 |
151 | RPS6KB1 | 0.03492390 |
152 | PRKCA | 0.03399555 |
153 | AURKA | 0.02463673 |
154 | GSK3B | 0.02321642 |
155 | PRKACA | 0.01744705 |
156 | CDK2 | 0.01720627 |
157 | PRKCI | 0.01678233 |
158 | STK11 | 0.00942176 |
159 | MET | 0.00858673 |
160 | IRAK3 | 0.00753334 |
161 | CSNK2A2 | 0.00326785 |
162 | RPS6KA1 | -0.0169337 |
163 | PRKG1 | -0.0163450 |
164 | MAPK8 | -0.0083516 |
165 | MAP3K2 | -0.0024733 |
166 | EEF2K | -0.0001391 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 3.67303470 |
2 | Propanoate metabolism_Homo sapiens_hsa00640 | 3.57816883 |
3 | Pyruvate metabolism_Homo sapiens_hsa00620 | 3.39248645 |
4 | Proteasome_Homo sapiens_hsa03050 | 3.20795820 |
5 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 3.19301371 |
6 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.73597081 |
7 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.47654098 |
8 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.46628561 |
9 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.26765346 |
10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.24531123 |
11 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 2.18431081 |
12 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.18307412 |
13 | Fatty acid metabolism_Homo sapiens_hsa01212 | 2.15794040 |
14 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.09525616 |
15 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.09393028 |
16 | Protein export_Homo sapiens_hsa03060 | 2.07384912 |
17 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.04391414 |
18 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.00659481 |
19 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.98293632 |
20 | Parkinsons disease_Homo sapiens_hsa05012 | 1.97379737 |
21 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.94462430 |
22 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.90139532 |
23 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.87662074 |
24 | Carbon metabolism_Homo sapiens_hsa01200 | 1.83903723 |
25 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.79496885 |
26 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.78623585 |
27 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.74867586 |
28 | Mineral absorption_Homo sapiens_hsa04978 | 1.74780675 |
29 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.74521831 |
30 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.71393282 |
31 | Basal transcription factors_Homo sapiens_hsa03022 | 1.69950572 |
32 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.66230193 |
33 | DNA replication_Homo sapiens_hsa03030 | 1.62191862 |
34 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.61756226 |
35 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.58561627 |
36 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.53544214 |
37 | Ribosome_Homo sapiens_hsa03010 | 1.52027479 |
38 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.51567364 |
39 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.49966024 |
40 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.48965516 |
41 | Peroxisome_Homo sapiens_hsa04146 | 1.45593752 |
42 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.42092663 |
43 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.41395885 |
44 | Homologous recombination_Homo sapiens_hsa03440 | 1.40405372 |
45 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.35814892 |
46 | RNA polymerase_Homo sapiens_hsa03020 | 1.35782035 |
47 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.33651981 |
48 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.32655919 |
49 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.31453559 |
50 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.30358150 |
51 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.29059854 |
52 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.28517987 |
53 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.27600144 |
54 | Bile secretion_Homo sapiens_hsa04976 | 1.27388516 |
55 | RNA degradation_Homo sapiens_hsa03018 | 1.24976335 |
56 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.24410297 |
57 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.23169905 |
58 | Alzheimers disease_Homo sapiens_hsa05010 | 1.22847903 |
59 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.21683665 |
60 | Mismatch repair_Homo sapiens_hsa03430 | 1.21369244 |
61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.20326021 |
62 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.19460833 |
63 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.17755150 |
64 | Sulfur relay system_Homo sapiens_hsa04122 | 1.15866259 |
65 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.15601311 |
66 | Base excision repair_Homo sapiens_hsa03410 | 1.14602727 |
67 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.13807427 |
68 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.08637131 |
69 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.08053973 |
70 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.07025049 |
71 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.05953073 |
72 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.05006151 |
73 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.04837485 |
74 | Lysine degradation_Homo sapiens_hsa00310 | 1.03318416 |
75 | Galactose metabolism_Homo sapiens_hsa00052 | 1.02740992 |
76 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.02636092 |
77 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.99197547 |
78 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.97938128 |
79 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.93195410 |
80 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.92365995 |
81 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.89614551 |
82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.87786813 |
83 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.87581675 |
84 | Huntingtons disease_Homo sapiens_hsa05016 | 0.87505423 |
85 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.87287804 |
86 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.85839808 |
87 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.82555731 |
88 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.82321209 |
89 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.81044751 |
90 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.80111830 |
91 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.79405503 |
92 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.75973176 |
93 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.74638226 |
94 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.71839493 |
95 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.69993607 |
96 | Metabolic pathways_Homo sapiens_hsa01100 | 0.67213174 |
97 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.66634439 |
98 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.66346261 |
99 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.65819769 |
100 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.65777849 |
101 | Other glycan degradation_Homo sapiens_hsa00511 | 0.65687619 |
102 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.65530859 |
103 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.64546624 |
104 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.64482427 |
105 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.61675816 |
106 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.60749696 |
107 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.60432707 |
108 | Spliceosome_Homo sapiens_hsa03040 | 0.59426244 |
109 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.58767353 |
110 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.58450379 |
111 | Insulin secretion_Homo sapiens_hsa04911 | 0.58306105 |
112 | Asthma_Homo sapiens_hsa05310 | 0.57707522 |
113 | Purine metabolism_Homo sapiens_hsa00230 | 0.54981018 |
114 | Histidine metabolism_Homo sapiens_hsa00340 | 0.54569613 |
115 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.53686113 |
116 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.52768334 |
117 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.52546105 |
118 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.49332529 |
119 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.48644111 |
120 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.47610248 |
121 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.45678937 |
122 | Olfactory transduction_Homo sapiens_hsa04740 | 0.44622285 |
123 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.41805766 |
124 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.40559397 |
125 | RNA transport_Homo sapiens_hsa03013 | 0.40334241 |
126 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.39274225 |
127 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.39048155 |
128 | Renin secretion_Homo sapiens_hsa04924 | 0.38794695 |
129 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.37136587 |
130 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.36522144 |
131 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.36029149 |
132 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.33462954 |
133 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.29381385 |
134 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.27764590 |
135 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.27296472 |
136 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.26506004 |
137 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.26279777 |
138 | ABC transporters_Homo sapiens_hsa02010 | 0.25385005 |
139 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.23226696 |
140 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.22877234 |
141 | Retinol metabolism_Homo sapiens_hsa00830 | 0.17245540 |