| 1 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 5.79693573 |
| 2 | Ependymoma (HP:0002888) | 4.85835651 |
| 3 | Birth length less than 3rd percentile (HP:0003561) | 4.77660669 |
| 4 | Selective tooth agenesis (HP:0001592) | 4.18979990 |
| 5 | Breast hypoplasia (HP:0003187) | 4.18742979 |
| 6 | Reticulocytosis (HP:0001923) | 3.96210501 |
| 7 | Abnormality of the labia minora (HP:0012880) | 3.91989653 |
| 8 | Medulloblastoma (HP:0002885) | 3.82181720 |
| 9 | Abnormal gallbladder physiology (HP:0012438) | 3.79684927 |
| 10 | Cholecystitis (HP:0001082) | 3.79684927 |
| 11 | Colon cancer (HP:0003003) | 3.75182587 |
| 12 | Truncus arteriosus (HP:0001660) | 3.65278341 |
| 13 | Poikilocytosis (HP:0004447) | 3.65122805 |
| 14 | Reticulocytopenia (HP:0001896) | 3.56209874 |
| 15 | Chromsome breakage (HP:0040012) | 3.55226185 |
| 16 | Abnormality of reticulocytes (HP:0004312) | 3.54195658 |
| 17 | Absent radius (HP:0003974) | 3.49944959 |
| 18 | Cortical dysplasia (HP:0002539) | 3.49119143 |
| 19 | Abnormality of the astrocytes (HP:0100707) | 3.46869819 |
| 20 | Astrocytoma (HP:0009592) | 3.46869819 |
| 21 | Carpal bone hypoplasia (HP:0001498) | 3.44998573 |
| 22 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.43989178 |
| 23 | Absent forearm bone (HP:0003953) | 3.28542938 |
| 24 | Aplasia involving forearm bones (HP:0009822) | 3.28542938 |
| 25 | Patellar aplasia (HP:0006443) | 3.23682614 |
| 26 | Agnosia (HP:0010524) | 3.22968419 |
| 27 | Degeneration of anterior horn cells (HP:0002398) | 3.22148695 |
| 28 | Abnormality of the anterior horn cell (HP:0006802) | 3.22148695 |
| 29 | Rhabdomyosarcoma (HP:0002859) | 3.16675278 |
| 30 | Glioma (HP:0009733) | 3.11715647 |
| 31 | Impulsivity (HP:0100710) | 3.10156558 |
| 32 | Neoplasm of the oral cavity (HP:0100649) | 3.08333386 |
| 33 | Supernumerary spleens (HP:0009799) | 3.07608477 |
| 34 | Meckel diverticulum (HP:0002245) | 3.03072625 |
| 35 | Aplasia/Hypoplasia of the patella (HP:0006498) | 3.02784998 |
| 36 | Oral leukoplakia (HP:0002745) | 2.98930231 |
| 37 | Absent thumb (HP:0009777) | 2.97117581 |
| 38 | Abnormality of chromosome stability (HP:0003220) | 2.90338045 |
| 39 | Abnormality of the ileum (HP:0001549) | 2.89823783 |
| 40 | Acanthocytosis (HP:0001927) | 2.81027466 |
| 41 | Abnormality of cochlea (HP:0000375) | 2.79973323 |
| 42 | Abnormality of the preputium (HP:0100587) | 2.78067264 |
| 43 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.76133478 |
| 44 | Rough bone trabeculation (HP:0100670) | 2.75459805 |
| 45 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.75457544 |
| 46 | Hyperthyroidism (HP:0000836) | 2.70937827 |
| 47 | Cholelithiasis (HP:0001081) | 2.69675487 |
| 48 | Microvesicular hepatic steatosis (HP:0001414) | 2.69137625 |
| 49 | Cerebral hypomyelination (HP:0006808) | 2.65992814 |
| 50 | Polycythemia (HP:0001901) | 2.61938440 |
| 51 | Neoplasm of the pancreas (HP:0002894) | 2.61456543 |
| 52 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.60841452 |
| 53 | Short middle phalanx of the 5th finger (HP:0004220) | 2.59471186 |
| 54 | Neoplasm of striated muscle (HP:0009728) | 2.54460379 |
| 55 | Abdominal situs inversus (HP:0003363) | 2.54433001 |
| 56 | Abnormality of abdominal situs (HP:0011620) | 2.54433001 |
| 57 | Horseshoe kidney (HP:0000085) | 2.52929818 |
| 58 | Abnormal number of incisors (HP:0011064) | 2.52913889 |
| 59 | Basal cell carcinoma (HP:0002671) | 2.52589191 |
| 60 | Biliary tract neoplasm (HP:0100574) | 2.46466514 |
| 61 | Bowel incontinence (HP:0002607) | 2.46316890 |
| 62 | Small intestinal stenosis (HP:0012848) | 2.45706543 |
| 63 | Duodenal stenosis (HP:0100867) | 2.45706543 |
| 64 | Volvulus (HP:0002580) | 2.45054294 |
| 65 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.44504817 |
| 66 | Seborrheic dermatitis (HP:0001051) | 2.43887512 |
| 67 | Ectopic kidney (HP:0000086) | 2.42523572 |
| 68 | Abnormal large intestine physiology (HP:0012700) | 2.41637874 |
| 69 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 2.41345617 |
| 70 | Abnormal gallbladder morphology (HP:0012437) | 2.41259437 |
| 71 | Duplicated collecting system (HP:0000081) | 2.36646992 |
| 72 | Acute myeloid leukemia (HP:0004808) | 2.36632111 |
| 73 | Short humerus (HP:0005792) | 2.36561143 |
| 74 | Ileus (HP:0002595) | 2.35977380 |
| 75 | Missing ribs (HP:0000921) | 2.34548787 |
| 76 | Stenosis of the external auditory canal (HP:0000402) | 2.32789800 |
| 77 | Hyperbilirubinemia (HP:0002904) | 2.28790795 |
| 78 | Proximal placement of thumb (HP:0009623) | 2.28750963 |
| 79 | Myelodysplasia (HP:0002863) | 2.26759987 |
| 80 | Hypoparathyroidism (HP:0000829) | 2.25758575 |
| 81 | Sloping forehead (HP:0000340) | 2.24730434 |
| 82 | Abnormal hemoglobin (HP:0011902) | 2.24153973 |
| 83 | Tracheoesophageal fistula (HP:0002575) | 2.24068287 |
| 84 | Premature graying of hair (HP:0002216) | 2.19800268 |
| 85 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.17899808 |
| 86 | Deviation of the thumb (HP:0009603) | 2.15453748 |
| 87 | Abnormal number of erythroid precursors (HP:0012131) | 2.14789802 |
| 88 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.14690926 |
| 89 | Trismus (HP:0000211) | 2.14499807 |
| 90 | Bone marrow hypocellularity (HP:0005528) | 2.13665440 |
| 91 | Gonadal dysgenesis (HP:0000133) | 2.13373544 |
| 92 | Acute lymphatic leukemia (HP:0006721) | 2.13309639 |
| 93 | Abnormality of the duodenum (HP:0002246) | 2.12976953 |
| 94 | Atresia of the external auditory canal (HP:0000413) | 2.11433125 |
| 95 | Triphalangeal thumb (HP:0001199) | 2.10563328 |
| 96 | 11 pairs of ribs (HP:0000878) | 2.09838300 |
| 97 | Premature ovarian failure (HP:0008209) | 2.09671335 |
| 98 | Esophageal atresia (HP:0002032) | 2.07519566 |
| 99 | Progressive muscle weakness (HP:0003323) | 2.06828808 |
| 100 | Amaurosis fugax (HP:0100576) | 2.06698097 |
| 101 | Paralysis (HP:0003470) | 2.05817782 |
| 102 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.05048638 |
| 103 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.05048638 |
| 104 | Increased nuchal translucency (HP:0010880) | 2.04061692 |
| 105 | Embryonal renal neoplasm (HP:0011794) | 2.03858305 |
| 106 | Macrocytic anemia (HP:0001972) | 2.02612914 |
| 107 | Rectal fistula (HP:0100590) | 2.01876620 |
| 108 | Rectovaginal fistula (HP:0000143) | 2.01876620 |
| 109 | Shawl scrotum (HP:0000049) | 1.98756732 |
| 110 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.98440726 |
| 111 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.97887543 |
| 112 | Spinal muscular atrophy (HP:0007269) | 1.96675832 |
| 113 | Abnormality of the renal collecting system (HP:0004742) | 1.96599359 |
| 114 | Abnormality of the carotid arteries (HP:0005344) | 1.96566976 |
| 115 | Cafe-au-lait spot (HP:0000957) | 1.95704377 |
| 116 | Morphological abnormality of the inner ear (HP:0011390) | 1.94536474 |
| 117 | Adenoma sebaceum (HP:0009720) | 1.93893361 |
| 118 | Angiofibromas (HP:0010615) | 1.93893361 |
| 119 | Neoplasm of the colon (HP:0100273) | 1.93876156 |
| 120 | Rib fusion (HP:0000902) | 1.93663284 |
| 121 | Neoplasm of the small intestine (HP:0100833) | 1.93577659 |
| 122 | Short thumb (HP:0009778) | 1.93021359 |
| 123 | Abnormal trabecular bone morphology (HP:0100671) | 1.92338568 |
| 124 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.91418697 |
| 125 | Abnormality of homocysteine metabolism (HP:0010919) | 1.91262525 |
| 126 | Homocystinuria (HP:0002156) | 1.91262525 |
| 127 | Abnormality of the salivary glands (HP:0010286) | 1.89698610 |
| 128 | Prominent nose (HP:0000448) | 1.89140146 |
| 129 | Hypoplasia of the radius (HP:0002984) | 1.89094088 |
| 130 | Pallor (HP:0000980) | 1.88412605 |
| 131 | Acute necrotizing encephalopathy (HP:0006965) | 1.88279392 |
| 132 | Prolonged bleeding time (HP:0003010) | 1.87751838 |
| 133 | Facial hemangioma (HP:0000329) | 1.87636904 |
| 134 | Abnormality of DNA repair (HP:0003254) | 1.87398950 |
| 135 | Acute encephalopathy (HP:0006846) | 1.86708076 |
| 136 | Ovarian neoplasm (HP:0100615) | 1.85871027 |
| 137 | Hypertensive crisis (HP:0100735) | 1.85354612 |
| 138 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.84836470 |
| 139 | Abnormality of alanine metabolism (HP:0010916) | 1.84836470 |
| 140 | Hyperalaninemia (HP:0003348) | 1.84836470 |
| 141 | Anal stenosis (HP:0002025) | 1.83671768 |
| 142 | Neoplasm of the rectum (HP:0100743) | 1.83665679 |
| 143 | Abnormal lung lobation (HP:0002101) | 1.83636443 |
| 144 | Increased serum pyruvate (HP:0003542) | 1.83038340 |
| 145 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.82500888 |
| 146 | Gastrointestinal carcinoma (HP:0002672) | 1.82154896 |
| 147 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.82154896 |
| 148 | Microretrognathia (HP:0000308) | 1.82122351 |
| 149 | Cerebral palsy (HP:0100021) | 1.81619095 |
| 150 | Aplastic anemia (HP:0001915) | 1.80699402 |
| 151 | Rimmed vacuoles (HP:0003805) | 1.80567461 |
| 152 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.77504939 |
| 153 | Multiple enchondromatosis (HP:0005701) | 1.75481887 |
| 154 | Abnormality of the gallbladder (HP:0005264) | 1.74995995 |
| 155 | Ankyloglossia (HP:0010296) | 1.72101023 |
| 156 | Abnormality of glycolysis (HP:0004366) | 1.68972545 |
| 157 | Pancytopenia (HP:0001876) | 1.68784933 |
| 158 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.68662625 |
| 159 | Progressive external ophthalmoplegia (HP:0000590) | 1.67821196 |
| 160 | Thrombocytosis (HP:0001894) | 1.67166014 |
ASH2L 
