ASNSD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proteasome assembly (GO:0043248)5.39905333
2DNA double-strand break processing (GO:0000729)4.83951039
3cullin deneddylation (GO:0010388)4.27983171
4non-recombinational repair (GO:0000726)4.17547072
5double-strand break repair via nonhomologous end joining (GO:0006303)4.17547072
6establishment of integrated proviral latency (GO:0075713)4.15399946
7rRNA modification (GO:0000154)4.11984509
8protein deneddylation (GO:0000338)4.01798113
9rRNA methylation (GO:0031167)3.97093220
10regulation of mitotic spindle checkpoint (GO:1903504)3.87358016
11regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.87358016
12nuclear pore complex assembly (GO:0051292)3.82806316
13DNA unwinding involved in DNA replication (GO:0006268)3.82056234
14nuclear pore organization (GO:0006999)3.77366024
15DNA strand elongation involved in DNA replication (GO:0006271)3.71295715
16DNA catabolic process, exonucleolytic (GO:0000738)3.69106676
17protein localization to chromosome, centromeric region (GO:0071459)3.68753597
18oxidative phosphorylation (GO:0006119)3.67902327
19mitochondrial RNA metabolic process (GO:0000959)3.67006479
20ribosomal small subunit assembly (GO:0000028)3.65953680
21replication fork processing (GO:0031297)3.64825918
22formation of translation preinitiation complex (GO:0001731)3.63968199
23mitotic nuclear envelope disassembly (GO:0007077)3.59510556
24DNA strand elongation (GO:0022616)3.53595076
25RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.52528829
26protein localization to kinetochore (GO:0034501)3.50810958
27exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.50324422
28DNA-dependent DNA replication (GO:0006261)3.49996571
29mitotic chromosome condensation (GO:0007076)3.49776884
30DNA replication-dependent nucleosome assembly (GO:0006335)3.49598733
31DNA replication-dependent nucleosome organization (GO:0034723)3.49598733
32regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.49210349
33negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.48998283
34regulation of centriole replication (GO:0046599)3.47960895
35folic acid-containing compound biosynthetic process (GO:0009396)3.47160538
36positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.39537417
37telomere maintenance via semi-conservative replication (GO:0032201)3.39311554
38DNA replication initiation (GO:0006270)3.39301987
39viral transcription (GO:0019083)3.38543039
40isotype switching (GO:0045190)3.37494466
41somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.37494466
42somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.37494466
43DNA ligation (GO:0006266)3.37049886
44binding of sperm to zona pellucida (GO:0007339)3.35973188
45nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.35515923
46translational termination (GO:0006415)3.34639038
47mitotic metaphase plate congression (GO:0007080)3.33852892
48anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.32980217
49nuclear envelope disassembly (GO:0051081)3.32507352
50membrane disassembly (GO:0030397)3.32507352
51establishment of viral latency (GO:0019043)3.31831444
52tRNA aminoacylation for protein translation (GO:0006418)3.28567121
53mitochondrial DNA replication (GO:0006264)3.28524026
54DNA damage response, detection of DNA damage (GO:0042769)3.28522262
55tRNA aminoacylation (GO:0043039)3.28183904
56amino acid activation (GO:0043038)3.28183904
57negative regulation of DNA-dependent DNA replication (GO:2000104)3.27762845
58sperm-egg recognition (GO:0035036)3.27004472
59translational elongation (GO:0006414)3.24092398
60negative regulation of DNA recombination (GO:0045910)3.23837355
61chromosome condensation (GO:0030261)3.22528405
62transcription from mitochondrial promoter (GO:0006390)3.22334663
63resolution of meiotic recombination intermediates (GO:0000712)3.19577849
64mitotic sister chromatid cohesion (GO:0007064)3.19015561
65telomere maintenance via recombination (GO:0000722)3.17571140
66negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.15467453
67negative regulation of ligase activity (GO:0051352)3.15467453
68spindle checkpoint (GO:0031577)3.15260121
69maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.13467230
70maturation of 5.8S rRNA (GO:0000460)3.11108834
71mitotic recombination (GO:0006312)3.10378991
72translational initiation (GO:0006413)3.04598861
73sister chromatid cohesion (GO:0007062)3.03975965
74nucleobase biosynthetic process (GO:0046112)3.03826518
75regulation of helicase activity (GO:0051095)3.03728805
76mitotic spindle checkpoint (GO:0071174)3.02981050
77positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.01668606
78protein-cofactor linkage (GO:0018065)3.00265975
79chromatin remodeling at centromere (GO:0031055)2.99980485
80DNA deamination (GO:0045006)2.99333765
81IMP metabolic process (GO:0046040)2.98603867
82maturation of SSU-rRNA (GO:0030490)2.98313282
83histone mRNA metabolic process (GO:0008334)2.98125011
84fusion of sperm to egg plasma membrane (GO:0007342)2.96137958
85lactate metabolic process (GO:0006089)2.96035183
86cell-cell recognition (GO:0009988)2.95210498
87pseudouridine synthesis (GO:0001522)2.95062812
88IMP biosynthetic process (GO:0006188)2.94736761
89positive regulation of ligase activity (GO:0051351)2.93810626
90translesion synthesis (GO:0019985)2.93719653
91negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.93260628
92negative regulation of mitotic sister chromatid segregation (GO:0033048)2.93260628
93negative regulation of mitotic sister chromatid separation (GO:2000816)2.93260628
94negative regulation of sister chromatid segregation (GO:0033046)2.93260628
95negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.93260628
96nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.92297992
97signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.91906984
98signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.91906984
99signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.91906984
100DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.91826451
101regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.90883624
102DNA packaging (GO:0006323)2.90543562
103ether lipid metabolic process (GO:0046485)2.90450540
104regulation of spindle organization (GO:0090224)2.89924394
105regulation of mitochondrial translation (GO:0070129)2.89243191
106purine nucleobase biosynthetic process (GO:0009113)2.89220406
107synapsis (GO:0007129)2.88989673
108histone exchange (GO:0043486)2.88757351
109intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.88326533
110signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.88326533
111SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.88298195
112metaphase plate congression (GO:0051310)2.88147709
113chaperone-mediated protein complex assembly (GO:0051131)2.87529475
114kinetochore organization (GO:0051383)2.87427100
115mitotic sister chromatid segregation (GO:0000070)2.87398251
116histone H2A acetylation (GO:0043968)2.86836629
117CENP-A containing nucleosome assembly (GO:0034080)2.86253514
118monoubiquitinated protein deubiquitination (GO:0035520)2.84489731
119DNA replication checkpoint (GO:0000076)2.82935512
120regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.78761352
121protein targeting to ER (GO:0045047)2.78660220
122pore complex assembly (GO:0046931)2.78287753
123sister chromatid segregation (GO:0000819)2.78272446
124DNA replication-independent nucleosome assembly (GO:0006336)2.77359255
125DNA replication-independent nucleosome organization (GO:0034724)2.77359255
126cotranslational protein targeting to membrane (GO:0006613)2.77265698
127establishment of chromosome localization (GO:0051303)2.75750959
128nucleotide-excision repair, DNA gap filling (GO:0006297)2.75457815
129synaptonemal complex assembly (GO:0007130)2.74360097
130meiotic chromosome segregation (GO:0045132)2.72797138
131regulation of histone H3-K9 methylation (GO:0051570)2.72433595
132attachment of spindle microtubules to kinetochore (GO:0008608)2.71799811
133piRNA metabolic process (GO:0034587)2.70518965
134ribosomal large subunit biogenesis (GO:0042273)2.69395481
135DNA duplex unwinding (GO:0032508)2.68523018
136DNA geometric change (GO:0032392)2.67434159
137ribosomal small subunit biogenesis (GO:0042274)2.66551622
138regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.65910738
139nuclear envelope organization (GO:0006998)2.65840579
140establishment of protein localization to endoplasmic reticulum (GO:0072599)2.65597330
141DNA conformation change (GO:0071103)2.65138347
142regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.64550835
143protein localization to chromosome (GO:0034502)2.64080324
144positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.64053269
145positive regulation of mitotic sister chromatid separation (GO:1901970)2.64053269
146positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.64053269
147synaptonemal complex organization (GO:0070193)2.62816202
148regulation of chromosome segregation (GO:0051983)2.62804901
149telomere maintenance via telomere lengthening (GO:0010833)2.62032091
150heterochromatin organization (GO:0070828)2.60799427
151protein localization to endoplasmic reticulum (GO:0070972)2.60566872
152positive regulation of chromosome segregation (GO:0051984)2.60512733
153cellular protein complex disassembly (GO:0043624)2.59474197
154viral life cycle (GO:0019058)2.59257128
155ribosome assembly (GO:0042255)2.58357675
156postreplication repair (GO:0006301)2.57354293
157somatic hypermutation of immunoglobulin genes (GO:0016446)2.53225610
158somatic diversification of immune receptors via somatic mutation (GO:0002566)2.53225610
159male meiosis (GO:0007140)2.49174767
160chromatin assembly or disassembly (GO:0006333)2.48920500
161regulation of centrosome cycle (GO:0046605)2.45971219
162regulation of mitotic spindle organization (GO:0060236)2.43345429
163gene silencing by RNA (GO:0031047)2.43252714
164protein complex disassembly (GO:0043241)2.41099251
165negative regulation of chromosome segregation (GO:0051985)2.41079322
166acrosome assembly (GO:0001675)2.40802141
167regulation of sister chromatid cohesion (GO:0007063)2.39720053
168regulation of mitotic metaphase/anaphase transition (GO:0030071)2.39190744

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.31966306
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.08788671
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.56249684
4MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.42352059
5* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.39069118
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.05682004
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.88108884
8SALL1_21062744_ChIP-ChIP_HESCs_Human2.72723047
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.39937010
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.34663341
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.30482210
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.28412301
13* FLI1_27457419_Chip-Seq_LIVER_Mouse2.09994859
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.04781694
15NELFA_20434984_ChIP-Seq_ESCs_Mouse2.02849991
16ZNF274_21170338_ChIP-Seq_K562_Hela2.01478514
17AR_21909140_ChIP-Seq_LNCAP_Human2.01201498
18POU3F2_20337985_ChIP-ChIP_501MEL_Human2.00315669
19GABP_17652178_ChIP-ChIP_JURKAT_Human2.00130687
20EST1_17652178_ChIP-ChIP_JURKAT_Human1.98887005
21EWS_26573619_Chip-Seq_HEK293_Human1.98885870
22ETS1_20019798_ChIP-Seq_JURKAT_Human1.97187901
23KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.95534503
24EGR1_19374776_ChIP-ChIP_THP-1_Human1.92174091
25JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.90888828
26* XRN2_22483619_ChIP-Seq_HELA_Human1.87916583
27MYC_22102868_ChIP-Seq_BL_Human1.87744985
28* VDR_23849224_ChIP-Seq_CD4+_Human1.83814786
29NOTCH1_21737748_ChIP-Seq_TLL_Human1.83088969
30* E2F1_21310950_ChIP-Seq_MCF-7_Human1.82368750
31FUS_26573619_Chip-Seq_HEK293_Human1.77949835
32ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.73290389
33SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.72107184
34DCP1A_22483619_ChIP-Seq_HELA_Human1.70956868
35MYCN_18555785_ChIP-Seq_MESCs_Mouse1.69801103
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69178455
37CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.66808294
38ELF1_17652178_ChIP-ChIP_JURKAT_Human1.65079547
39TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.64883625
40IGF1R_20145208_ChIP-Seq_DFB_Human1.62862613
41MYC_18940864_ChIP-ChIP_HL60_Human1.62416038
42FOXP3_21729870_ChIP-Seq_TREG_Human1.61568139
43* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.61100611
44* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.58261271
45ZFX_18555785_ChIP-Seq_MESCs_Mouse1.56266122
46* GABP_19822575_ChIP-Seq_HepG2_Human1.49388226
47MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.48861802
48STAT3_1855785_ChIP-Seq_MESCs_Mouse1.47149741
49ZFP57_27257070_Chip-Seq_ESCs_Mouse1.46057975
50HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.45596582
51PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.43201621
52KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.40491276
53HOXB4_20404135_ChIP-ChIP_EML_Mouse1.40301987
54TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.38918334
55RBPJ_22232070_ChIP-Seq_NCS_Mouse1.35640972
56KDM5A_27292631_Chip-Seq_BREAST_Human1.34830123
57TTF2_22483619_ChIP-Seq_HELA_Human1.34793564
58ELK1_19687146_ChIP-ChIP_HELA_Human1.32737513
59ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.32177416
60PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.32034403
61POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.31256223
62SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.30493030
63SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.29477416
64KLF4_18555785_ChIP-Seq_MESCs_Mouse1.29217039
65CIITA_25753668_ChIP-Seq_RAJI_Human1.26911218
66FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.26712568
67GBX2_23144817_ChIP-Seq_PC3_Human1.26481857
68VDR_21846776_ChIP-Seq_THP-1_Human1.25578574
69FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.24551419
70NANOG_18555785_ChIP-Seq_MESCs_Mouse1.24464048
71TAF15_26573619_Chip-Seq_HEK293_Human1.23852230
72ERG_20887958_ChIP-Seq_HPC-7_Mouse1.23688031
73SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.23367255
74CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.22505401
75* PCGF2_27294783_Chip-Seq_NPCs_Mouse1.19989342
76* EZH2_27294783_Chip-Seq_NPCs_Mouse1.19584188
77IRF8_22096565_ChIP-ChIP_GC-B_Human1.17641416
78TFEB_21752829_ChIP-Seq_HELA_Human1.17278356
79* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.15731692
80POU5F1_16153702_ChIP-ChIP_HESCs_Human1.15593073
81TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.14987628
82PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.14665747
83ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.14449865
84SPI1_23547873_ChIP-Seq_NB4_Human1.13735100
85FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.13231829
86VDR_22108803_ChIP-Seq_LS180_Human1.13135848
87CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11699257
88E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.10845529
89CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.10802140
90DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.10098098
91NANOG_16153702_ChIP-ChIP_HESCs_Human1.08364171
92IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.08280368
93P300_19829295_ChIP-Seq_ESCs_Human1.07607293
94NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.07094101
95* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.06268090
96* NFE2_27457419_Chip-Seq_LIVER_Mouse1.06137081
97BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.05600811
98* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.04902051
99POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.04848358
100* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.04557480
101CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.02564959
102CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.02383148
103TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02059107
104SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.00031895
105SRF_21415370_ChIP-Seq_HL-1_Mouse0.97722138
106RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.97468799
107NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.97381904
108HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.97203128
109YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96283730
110* MYB_26560356_Chip-Seq_TH2_Human0.94556698
111FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.94378075
112THAP11_20581084_ChIP-Seq_MESCs_Mouse0.93984084
113PADI4_21655091_ChIP-ChIP_MCF-7_Human0.93606982
114MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.93388094
115CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.93211864
116PPARA_22158963_ChIP-Seq_LIVER_Mouse0.93193941
117RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.92298988
118GATA2_22383799_ChIP-Seq_G1ME_Mouse0.92148990
119* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.91962216
120* MAF_26560356_Chip-Seq_TH1_Human0.91910243
121CTBP1_25329375_ChIP-Seq_LNCAP_Human0.91393793
122MYB_26560356_Chip-Seq_TH1_Human0.91086726
123YY1_21170310_ChIP-Seq_MESCs_Mouse0.90487157
124* UTX_26944678_Chip-Seq_JUKART_Human0.90357824
125* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.90133937
126ER_23166858_ChIP-Seq_MCF-7_Human0.89966208
127SOX2_16153702_ChIP-ChIP_HESCs_Human0.89957700
128TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.89873340
129GATA1_22383799_ChIP-Seq_G1ME_Mouse0.89287281
130POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88828929
131GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.87946076
132* SOX17_20123909_ChIP-Seq_XEN_Mouse0.87145166
133RUNX1_22412390_ChIP-Seq_EML_Mouse0.86465827
134MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.86152707
135* CRX_20693478_ChIP-Seq_RETINA_Mouse0.85728987
136HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.85643470
137CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.85623157
138SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85147944
139DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.82527955
140MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.82525556
141CTBP2_25329375_ChIP-Seq_LNCAP_Human0.81802978
142* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.81793623
143* NANOG_18555785_Chip-Seq_ESCs_Mouse0.81330610
144HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.80501394
145ELK1_22589737_ChIP-Seq_MCF10A_Human0.80494344

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.64856492
2MP0010094_abnormal_chromosome_stability3.26067653
3MP0004957_abnormal_blastocyst_morpholog3.02198478
4MP0003111_abnormal_nucleus_morphology2.92367811
5MP0003077_abnormal_cell_cycle2.80844153
6MP0002102_abnormal_ear_morphology2.44488857
7MP0005410_abnormal_fertilization2.35332379
8MP0008057_abnormal_DNA_replication2.30399748
9MP0009697_abnormal_copulation2.29072045
10MP0006035_abnormal_mitochondrial_morpho2.23748450
11MP0010352_gastrointestinal_tract_polyps2.19038418
12MP0003806_abnormal_nucleotide_metabolis2.13109754
13MP0008058_abnormal_DNA_repair2.09716620
14MP0003705_abnormal_hypodermis_morpholog2.02689736
15MP0006072_abnormal_retinal_apoptosis1.91058651
16MP0010307_abnormal_tumor_latency1.90978962
17MP0001529_abnormal_vocalization1.89479002
18MP0008007_abnormal_cellular_replicative1.88521608
19MP0001730_embryonic_growth_arrest1.77960336
20MP0003195_calcinosis1.72397749
21MP0008877_abnormal_DNA_methylation1.63926222
22MP0003941_abnormal_skin_development1.63900565
23MP0002396_abnormal_hematopoietic_system1.60019286
24MP0000350_abnormal_cell_proliferation1.59151383
25MP0001661_extended_life_span1.58901202
26MP0001177_atelectasis1.56731713
27MP0004808_abnormal_hematopoietic_stem1.51629860
28MP0001929_abnormal_gametogenesis1.50571542
29MP0000490_abnormal_crypts_of1.48321996
30MP0002234_abnormal_pharynx_morphology1.41595548
31MP0001764_abnormal_homeostasis1.39091311
32MP0002160_abnormal_reproductive_system1.38881866
33MP0008932_abnormal_embryonic_tissue1.33899605
34MP0006054_spinal_hemorrhage1.33807910
35MP0003646_muscle_fatigue1.33123438
36MP0001697_abnormal_embryo_size1.31428973
37MP0003186_abnormal_redox_activity1.27861361
38MP0002837_dystrophic_cardiac_calcinosis1.27683824
39MP0005380_embryogenesis_phenotype1.27074071
40MP0001672_abnormal_embryogenesis/_devel1.27074071
41MP0006036_abnormal_mitochondrial_physio1.26965337
42MP0002019_abnormal_tumor_incidence1.26436218
43MP0005076_abnormal_cell_differentiation1.26319179
44MP0005253_abnormal_eye_physiology1.25946654
45MP0002736_abnormal_nociception_after1.24925747
46MP0001984_abnormal_olfaction1.23751711
47MP0004215_abnormal_myocardial_fiber1.23074349
48MP0002139_abnormal_hepatobiliary_system1.22420156
49MP0006292_abnormal_olfactory_placode1.22364776
50MP0003984_embryonic_growth_retardation1.21204095
51MP0003221_abnormal_cardiomyocyte_apopto1.20882609
52MP0002210_abnormal_sex_determination1.20846100
53MP0002080_prenatal_lethality1.20401041
54MP0003763_abnormal_thymus_physiology1.20357407
55MP0004043_abnormal_pH_regulation1.19113330
56MP0002088_abnormal_embryonic_growth/wei1.18703728
57MP0003937_abnormal_limbs/digits/tail_de1.17904710
58MP0002233_abnormal_nose_morphology1.17347245
59MP0004197_abnormal_fetal_growth/weight/1.15404156
60MP0005645_abnormal_hypothalamus_physiol1.13965506
61MP0000313_abnormal_cell_death1.13177989
62MP0002086_abnormal_extraembryonic_tissu1.13142448
63MP0003567_abnormal_fetal_cardiomyocyte1.12971989
64MP0001145_abnormal_male_reproductive1.12674881
65MP0002938_white_spotting1.12589449
66MP0001835_abnormal_antigen_presentation1.12557024
67MP0005397_hematopoietic_system_phenotyp1.12037905
68MP0001545_abnormal_hematopoietic_system1.12037905
69MP0003786_premature_aging1.10552553
70MP0003656_abnormal_erythrocyte_physiolo1.10348352
71MP0004145_abnormal_muscle_electrophysio1.10200641
72MP0002398_abnormal_bone_marrow1.09743956
73MP0000689_abnormal_spleen_morphology1.09140640
74MP0009333_abnormal_splenocyte_physiolog1.07381069
75MP0005408_hypopigmentation1.07291035
76MP0003121_genomic_imprinting1.06488966
77MP0003698_abnormal_male_reproductive1.05921553
78MP0002166_altered_tumor_susceptibility1.05190282
79MP0002722_abnormal_immune_system1.03911377
80MP0000647_abnormal_sebaceous_gland1.01871810
81MP0005365_abnormal_bile_salt1.01248443
82MP0005623_abnormal_meninges_morphology1.00535499
83MP0000358_abnormal_cell_content/0.99830331
84MP0000685_abnormal_immune_system0.99038081
85MP0005187_abnormal_penis_morphology0.97606334
86MP0004147_increased_porphyrin_level0.97548121
87MP0000749_muscle_degeneration0.97324227
88MP0002084_abnormal_developmental_patter0.96795916
89MP0002085_abnormal_embryonic_tissue0.96334488
90MP0009053_abnormal_anal_canal0.96227145
91MP0005083_abnormal_biliary_tract0.93971902
92MP0000653_abnormal_sex_gland0.93698186
93MP0005360_urolithiasis0.93612349
94MP0000858_altered_metastatic_potential0.93586519
95MP0005389_reproductive_system_phenotype0.93111649
96MP0003123_paternal_imprinting0.92990679
97MP0001286_abnormal_eye_development0.92718997
98MP0005023_abnormal_wound_healing0.92596368
99MP0001800_abnormal_humoral_immune0.92539811
100MP0002269_muscular_atrophy0.91355597
101MP0003566_abnormal_cell_adhesion0.90405482
102MP0000703_abnormal_thymus_morphology0.90351884
103MP0002697_abnormal_eye_size0.89780213
104MP0005266_abnormal_metabolism0.89036667
105MP0009840_abnormal_foam_cell0.88792659
106MP0000631_abnormal_neuroendocrine_gland0.88226889
107MP0002429_abnormal_blood_cell0.88203858
108MP0000733_abnormal_muscle_development0.88143795
109MP0000598_abnormal_liver_morphology0.87085240
110MP0009278_abnormal_bone_marrow0.86793351
111MP0002751_abnormal_autonomic_nervous0.86005492
112MP0001853_heart_inflammation0.85730883
113MP0003436_decreased_susceptibility_to0.85586676
114MP0005330_cardiomyopathy0.85198341
115MP0003890_abnormal_embryonic-extraembry0.85063928
116MP0002405_respiratory_system_inflammati0.84987538
117MP0004084_abnormal_cardiac_muscle0.84496862
118MP0004233_abnormal_muscle_weight0.81481200
119MP0001119_abnormal_female_reproductive0.80709188
120MP0000716_abnormal_immune_system0.80623230
121MP0000750_abnormal_muscle_regeneration0.80538872
122MP0002452_abnormal_antigen_presenting0.80027107
123MP0002090_abnormal_vision0.79941141
124MP0001299_abnormal_eye_distance/0.79900701
125MP0001915_intracranial_hemorrhage0.79836531
126MP0009250_abnormal_appendicular_skeleto0.78928729
127MP0000427_abnormal_hair_cycle0.78107240
128MP0003950_abnormal_plasma_membrane0.77881626
129MP0005085_abnormal_gallbladder_physiolo0.76880172
130MP0000609_abnormal_liver_physiology0.76393531
131MP0001666_abnormal_nutrient_absorption0.76294595
132MP0005391_vision/eye_phenotype0.76247519
133MP0003119_abnormal_digestive_system0.76037133
134MP0005319_abnormal_enzyme/_coenzyme0.74839906
135MP0010234_abnormal_vibrissa_follicle0.74568204
136MP0002420_abnormal_adaptive_immunity0.74438747
137MP0010630_abnormal_cardiac_muscle0.74370757
138MP0009672_abnormal_birth_weight0.73924000
139MP0002006_tumorigenesis0.73737049
140MP0009046_muscle_twitch0.73660757
141MP0001819_abnormal_immune_cell0.72643373
142MP0008438_abnormal_cutaneous_collagen0.72552934
143MP0003718_maternal_effect0.72551509
144MP0004087_abnormal_muscle_fiber0.72058791
145MP0000371_diluted_coat_color0.71688296
146MP0000049_abnormal_middle_ear0.71423253
147MP0008873_increased_physiological_sensi0.71230353
148MP0001873_stomach_inflammation0.70208100
149MP0005464_abnormal_platelet_physiology0.70190435
150MP0001293_anophthalmia0.70044485
151MP0009703_decreased_birth_body0.67959520
152MP0008789_abnormal_olfactory_epithelium0.65804628
153MP0003755_abnormal_palate_morphology0.65718228
154MP0008995_early_reproductive_senescence0.65173713
155MP0005075_abnormal_melanosome_morpholog0.64880642
156MP0005551_abnormal_eye_electrophysiolog0.64542989
157MP0000516_abnormal_urinary_system0.64514289

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the labia minora (HP:0012880)4.00222916
2Abnormality of cells of the erythroid lineage (HP:0012130)3.34704817
3Degeneration of anterior horn cells (HP:0002398)3.32609696
4Abnormality of the anterior horn cell (HP:0006802)3.32609696
5Rhabdomyolysis (HP:0003201)3.31241791
6Reduced antithrombin III activity (HP:0001976)3.29541566
7Nasal polyposis (HP:0100582)3.28325721
8Reticulocytopenia (HP:0001896)3.19798674
9Chromosomal breakage induced by crosslinking agents (HP:0003221)3.09713708
10Abnormal number of erythroid precursors (HP:0012131)3.04940009
11Thrombocytosis (HP:0001894)3.03077821
12Volvulus (HP:0002580)2.97903239
13Abnormal lung lobation (HP:0002101)2.97569811
14Multiple enchondromatosis (HP:0005701)2.94539839
15Increased serum pyruvate (HP:0003542)2.92749400
16Exercise-induced muscle cramps (HP:0003710)2.83281335
17Acute necrotizing encephalopathy (HP:0006965)2.79536053
18Methylmalonic acidemia (HP:0002912)2.70331561
19Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.69772587
20Abnormality of alanine metabolism (HP:0010916)2.69772587
21Hyperalaninemia (HP:0003348)2.69772587
22Myoglobinuria (HP:0002913)2.69491621
23Increased hepatocellular lipid droplets (HP:0006565)2.69077514
24Abnormality of the nasal mucosa (HP:0000433)2.68341367
25Increased CSF lactate (HP:0002490)2.64623428
26Abnormality of methionine metabolism (HP:0010901)2.62582744
27Type I transferrin isoform profile (HP:0003642)2.61213236
28Selective tooth agenesis (HP:0001592)2.58347956
29Chronic bronchitis (HP:0004469)2.55751556
30Ulnar deviation of the wrist (HP:0003049)2.55749923
31Increased serum lactate (HP:0002151)2.52546788
32Neoplasm of the adrenal gland (HP:0100631)2.52075813
33Abnormality of glycolysis (HP:0004366)2.51471874
34Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.48370988
35Acute encephalopathy (HP:0006846)2.47203410
36Abnormality of serum amino acid levels (HP:0003112)2.46655892
37Bronchitis (HP:0012387)2.46114447
38Progressive macrocephaly (HP:0004481)2.45696950
39Lipid accumulation in hepatocytes (HP:0006561)2.45018875
40Progressive inability to walk (HP:0002505)2.44164998
413-Methylglutaconic aciduria (HP:0003535)2.40227689
42Glioma (HP:0009733)2.40028739
43Recurrent bronchitis (HP:0002837)2.39689708
44Abnormality of aspartate family amino acid metabolism (HP:0010899)2.38014235
45Oral leukoplakia (HP:0002745)2.37411450
46Muscle fiber inclusion bodies (HP:0100299)2.36955773
47Abnormal protein glycosylation (HP:0012346)2.36680987
48Abnormal glycosylation (HP:0012345)2.36680987
49Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.36680987
50Abnormal protein N-linked glycosylation (HP:0012347)2.36680987
51Abnormal mitochondria in muscle tissue (HP:0008316)2.35755855
52Mitochondrial inheritance (HP:0001427)2.35177508
53Cerebral edema (HP:0002181)2.31746728
54Colon cancer (HP:0003003)2.30685813
55Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.29936420
56Neoplasm of the oral cavity (HP:0100649)2.27350806
57Astrocytoma (HP:0009592)2.22550227
58Abnormality of the astrocytes (HP:0100707)2.22550227
59Birth length less than 3rd percentile (HP:0003561)2.22396418
60Hepatic necrosis (HP:0002605)2.21554267
61Hepatocellular necrosis (HP:0001404)2.20775922
62Carpal bone hypoplasia (HP:0001498)2.19819641
63Megaloblastic anemia (HP:0001889)2.18551147
64Calcaneovalgus deformity (HP:0001848)2.16972042
65Nemaline bodies (HP:0003798)2.16538151
66Abnormal spermatogenesis (HP:0008669)2.14709474
67Abnormality of the calcaneus (HP:0008364)2.14301248
68Biliary tract neoplasm (HP:0100574)2.14013051
69Hypoglycemic coma (HP:0001325)2.11465255
70Abnormality of the metopic suture (HP:0005556)2.11251666
71Abnormality of chromosome stability (HP:0003220)2.11234556
72Impulsivity (HP:0100710)2.10765500
73Aplastic anemia (HP:0001915)2.09671679
74Agnosia (HP:0010524)2.09633000
75Abnormality of pyrimidine metabolism (HP:0004353)2.09587210
76Lactic acidosis (HP:0003128)2.05963064
77Long clavicles (HP:0000890)2.04301992
78Neoplasm of the adrenal cortex (HP:0100641)2.04262808
79Basal cell carcinoma (HP:0002671)2.03442836
80Prominent metopic ridge (HP:0005487)2.02951252
81Abnormality of the duodenum (HP:0002246)2.00598115
82Microvesicular hepatic steatosis (HP:0001414)2.00485164
83Embryonal renal neoplasm (HP:0011794)2.00156800
84Methylmalonic aciduria (HP:0012120)1.99330088
85Nephroblastoma (Wilms tumor) (HP:0002667)1.99325316
86Absent thumb (HP:0009777)1.99142667
87IgM deficiency (HP:0002850)1.98448240
88Ependymoma (HP:0002888)1.95722362
89Deformed tarsal bones (HP:0008119)1.95549829
90Medulloblastoma (HP:0002885)1.94306659
9111 pairs of ribs (HP:0000878)1.93997034
92High pitched voice (HP:0001620)1.93671210
93Myelodysplasia (HP:0002863)1.91777904
94Pancreatic islet-cell hyperplasia (HP:0004510)1.91683632
95Postnatal microcephaly (HP:0005484)1.91361228
96Renal cortical cysts (HP:0000803)1.90944621
97Abnormality of reticulocytes (HP:0004312)1.90893814
98Adrenal hypoplasia (HP:0000835)1.89289599
99Hypobetalipoproteinemia (HP:0003563)1.88872388
100Submucous cleft hard palate (HP:0000176)1.88785132
101Hyperinsulinemic hypoglycemia (HP:0000825)1.87835585
102Recurrent sinusitis (HP:0011108)1.87421123
103Abnormality of T cell physiology (HP:0011840)1.86781941
104Broad-based gait (HP:0002136)1.86390753
105Pallor (HP:0000980)1.86222253
106Rhabdomyosarcoma (HP:0002859)1.84748362
107Macrocytic anemia (HP:0001972)1.84340623
108Triphalangeal thumb (HP:0001199)1.83758153
109Abnormality of the carotid arteries (HP:0005344)1.83426260
110Distal arthrogryposis (HP:0005684)1.82559941
111Myopathic facies (HP:0002058)1.81728637
112Gonadotropin excess (HP:0000837)1.81603217
113Progressive muscle weakness (HP:0003323)1.80645967
114Short tibia (HP:0005736)1.79136034
115Sloping forehead (HP:0000340)1.78626474
116Rectal prolapse (HP:0002035)1.77884073
117Nausea (HP:0002018)1.77774597
118Medial flaring of the eyebrow (HP:0010747)1.76694471
119Abnormality of the umbilical cord (HP:0010881)1.75415014
120Clubbing of toes (HP:0100760)1.75367530
121Neoplasm of the pancreas (HP:0002894)1.74624931
122Exercise intolerance (HP:0003546)1.74367637
123Dyschromatopsia (HP:0007641)1.74158437
124Entropion (HP:0000621)1.72431638
125Hypoglycemic seizures (HP:0002173)1.71228834
126Asymmetric septal hypertrophy (HP:0001670)1.71228042
127Chromsome breakage (HP:0040012)1.71169965
128Abnormality of the vitamin B12 metabolism (HP:0004341)1.70203123
129Prominent nose (HP:0000448)1.70091160
130Abnormal cartilage morphology (HP:0002763)1.69729039
131Difficulty climbing stairs (HP:0003551)1.69585121
132Pelvic girdle muscle weakness (HP:0003749)1.69358831
133Abnormality of lateral ventricle (HP:0030047)1.67854657
134Abnormality of T cells (HP:0002843)1.67127989
135Hypoplasia of the capital femoral epiphysis (HP:0003090)1.65996745
136Shoulder girdle muscle weakness (HP:0003547)1.65987002
137Abnormality of serine family amino acid metabolism (HP:0010894)1.65655388
138Abnormality of glycine metabolism (HP:0010895)1.65655388
139Squamous cell carcinoma (HP:0002860)1.64393504
140Posterior subcapsular cataract (HP:0007787)1.63469957
141Aplasia/Hypoplasia of the uvula (HP:0010293)1.63047828
142Increased density of long bones (HP:0006392)1.62822540
143Neoplasm of the colon (HP:0100273)1.62646737
144Absent/shortened dynein arms (HP:0200106)1.62535247
145Dynein arm defect of respiratory motile cilia (HP:0012255)1.62535247
146Aplasia/Hypoplasia of the sternum (HP:0006714)1.62531204
147Meckel diverticulum (HP:0002245)1.62319756
148Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.62121304
149Type 2 muscle fiber atrophy (HP:0003554)1.62084658
150Neoplasm of the rectum (HP:0100743)1.61972161
151Respiratory failure (HP:0002878)1.61613826
152Leukodystrophy (HP:0002415)1.61135713
153Atrophy/Degeneration involving motor neurons (HP:0007373)1.60747646
154Abnormal biliary tract morphology (HP:0012440)1.60533581
155Inability to walk (HP:0002540)1.60311927
156Proximal placement of thumb (HP:0009623)1.60132901
157Supernumerary spleens (HP:0009799)1.60079420
158Breast hypoplasia (HP:0003187)1.59875559
159Cutaneous melanoma (HP:0012056)1.59803383
160Male infertility (HP:0003251)1.59240672
161Deviation of the thumb (HP:0009603)1.58769644
162Abnormality of the ileum (HP:0001549)1.58469089
163Spastic diplegia (HP:0001264)1.58017503
164Ovarian neoplasm (HP:0100615)1.57708213
165Increased connective tissue (HP:0009025)1.57608054
166Recurrent viral infections (HP:0004429)1.56329615
167Abnormality of the preputium (HP:0100587)1.55133709
168Poikiloderma (HP:0001029)1.55048170
169Abnormality of monocarboxylic acid metabolism (HP:0010996)1.54646225
170Trismus (HP:0000211)1.54038927
171Exercise-induced myalgia (HP:0003738)1.53132433
172Personality changes (HP:0000751)1.52888599
173Small intestinal stenosis (HP:0012848)1.52557833
174Duodenal stenosis (HP:0100867)1.52557833
175Acute myeloid leukemia (HP:0004808)1.51696072
176Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.50734053
177Hyperammonemia (HP:0001987)1.50317808
178Microretrognathia (HP:0000308)1.49951283
179Missing ribs (HP:0000921)1.49854148
180Decreased activity of mitochondrial respiratory chain (HP:0008972)1.48951148

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIM283.33600673
2PDK33.27206608
3PDK43.27206608
4NEK23.03411682
5CDC72.88660572
6BCR2.86784410
7WEE12.80068865
8PKN22.72167367
9NUAK12.66124805
10PBK2.52917815
11BUB12.28954023
12EEF2K2.19397345
13NME22.18240620
14ERBB32.16511485
15TESK12.15687570
16ACVR1B2.03309567
17NEK12.02078118
18PDK22.01591042
19FLT32.00012297
20TRIB31.92086178
21MAP4K11.87684031
22EIF2AK11.86717732
23BCKDK1.81518716
24MAP3K101.79915013
25VRK21.72866916
26MKNK11.72526261
27WNK31.70335158
28TTK1.69109026
29MKNK21.67682440
30TTN1.64882626
31STK101.60530633
32RPS6KA41.59402023
33SCYL21.57914242
34MAP2K31.54993487
35PASK1.53648396
36BRSK21.52152888
37EIF2AK31.43111627
38RPS6KB21.42606034
39MST41.41024447
40PLK21.37689368
41LRRK21.37410093
42CSNK1G21.30446247
43MAP3K81.29891106
44DYRK31.29729046
45PLK11.29665103
46EIF2AK21.28571815
47CDK41.27855973
48AURKB1.27623868
49TESK21.26591085
50CSNK1G31.26437836
51CSNK1G11.23337466
52PLK41.23132775
53ATR1.19129421
54BMPR1B1.16590683
55SRPK11.15205976
56CDK121.14775608
57PAK41.09196712
58CSNK1A1L1.07335918
59STK31.06756656
60TGFBR11.06199826
61TAF11.04314595
62STK41.03949766
63CDK71.03159802
64CAMKK21.02533467
65FRK1.01166207
66CDK61.00632190
67TYK20.99895145
68TGFBR20.97461479
69CHEK20.95847315
70NEK90.95485240
71ZAP700.94985235
72MAPKAPK30.94204308
73ERN10.92800293
74PIM10.91018139
75TNIK0.87811024
76BTK0.85809912
77MAP3K110.80443510
78JAK30.80075746
79CSF1R0.79394819
80OBSCN0.79151310
81CHEK10.78982955
82CLK10.78729374
83MAP4K20.78032703
84MAP3K30.76373313
85TLK10.75901011
86MAP3K120.75361219
87NME10.75163641
88AURKA0.72782174
89TXK0.71687517
90CCNB10.68451021
91TEC0.68230724
92MELK0.67139983
93BRSK10.65971737
94BRD40.65390759
95ATM0.64691455
96LATS10.63848386
97CDK30.61931041
98MAPK110.61024619
99GRK60.60774110
100STK390.58980048
101MAP3K40.58654030
102MAP3K50.57514480
103PTK60.56900611
104DYRK1B0.54494849
105FGFR20.53281336
106PNCK0.53055697
107KDR0.52950948
108MUSK0.52923309
109PLK30.51596219
110STK240.51504967
111KIT0.48241360
112ITK0.47674917
113MINK10.47626477
114VRK10.47237267
115ICK0.47180086
116ILK0.46828704
117MTOR0.46701377
118PRKDC0.46667272
119ALK0.46569641
120CDK20.44550183
121TAOK20.43092294
122EPHA40.42861712
123STK160.42842715
124TBK10.42699414
125STK38L0.42645658
126CSNK2A10.42535829
127CSNK2A20.41658724
128FGFR40.41570093
129MAP2K60.41532197
130LIMK10.40664824
131BLK0.40176679
132ZAK0.39505671
133CSNK1E0.37609109
134PHKG10.37591523
135PHKG20.37591523
136ERBB40.37135872
137PAK10.36478710
138MARK30.36054201
139MAP2K70.35742861
140TIE10.34860354
141CAMK2A0.33549044
142PAK20.33193768
143PINK10.33181182
144SIK30.32573821
145DAPK10.32221406
146PIK3CG0.31956869
147CASK0.31349683
148FGFR10.30978235
149TSSK60.30218263
150TRPM70.29495918
151PRKCE0.29465074
152CSNK1D0.28195658
153OXSR10.26754498
154CDK10.26226822
155DYRK20.22547845

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.91237503
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.30084835
3Mismatch repair_Homo sapiens_hsa034303.17917099
4Ribosome_Homo sapiens_hsa030102.59901336
5RNA transport_Homo sapiens_hsa030132.38735381
6Base excision repair_Homo sapiens_hsa034102.37656978
7One carbon pool by folate_Homo sapiens_hsa006702.36586207
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.26357506
9Homologous recombination_Homo sapiens_hsa034402.20244364
10Cell cycle_Homo sapiens_hsa041102.16290382
11Nucleotide excision repair_Homo sapiens_hsa034202.16084400
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.06858588
13Spliceosome_Homo sapiens_hsa030402.04636840
14Proteasome_Homo sapiens_hsa030501.92875007
15Selenocompound metabolism_Homo sapiens_hsa004501.84155190
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.74662750
17Pyrimidine metabolism_Homo sapiens_hsa002401.71200334
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.71066520
19Fanconi anemia pathway_Homo sapiens_hsa034601.65100940
20Pentose phosphate pathway_Homo sapiens_hsa000301.58228268
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.52794158
22Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.52134437
23Oxidative phosphorylation_Homo sapiens_hsa001901.51565348
24Carbon metabolism_Homo sapiens_hsa012001.51503311
25Biosynthesis of amino acids_Homo sapiens_hsa012301.48340790
26Parkinsons disease_Homo sapiens_hsa050121.43991618
27Non-homologous end-joining_Homo sapiens_hsa034501.40824296
28RNA degradation_Homo sapiens_hsa030181.40473599
29p53 signaling pathway_Homo sapiens_hsa041151.38059244
30Propanoate metabolism_Homo sapiens_hsa006401.36872535
31Steroid biosynthesis_Homo sapiens_hsa001001.36234366
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.29145399
33Antigen processing and presentation_Homo sapiens_hsa046121.29132355
34Fatty acid elongation_Homo sapiens_hsa000621.26439602
35RNA polymerase_Homo sapiens_hsa030201.26214210
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.25493616
37Cysteine and methionine metabolism_Homo sapiens_hsa002701.23837238
38Basal transcription factors_Homo sapiens_hsa030221.21256816
39Pyruvate metabolism_Homo sapiens_hsa006201.20577941
40mRNA surveillance pathway_Homo sapiens_hsa030151.20417854
41Systemic lupus erythematosus_Homo sapiens_hsa053221.18899405
42Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.17186330
43Regulation of autophagy_Homo sapiens_hsa041401.11554472
44Fatty acid degradation_Homo sapiens_hsa000711.10038312
45Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.07945617
46Sulfur relay system_Homo sapiens_hsa041221.06510435
47Butanoate metabolism_Homo sapiens_hsa006501.05937291
48Legionellosis_Homo sapiens_hsa051341.01227863
49Drug metabolism - other enzymes_Homo sapiens_hsa009831.00385244
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.00205228
51Folate biosynthesis_Homo sapiens_hsa007900.96336922
52Huntingtons disease_Homo sapiens_hsa050160.96324899
53Herpes simplex infection_Homo sapiens_hsa051680.95618466
54Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.92652346
55Epstein-Barr virus infection_Homo sapiens_hsa051690.92596825
56Viral carcinogenesis_Homo sapiens_hsa052030.91698674
57Vitamin B6 metabolism_Homo sapiens_hsa007500.90979015
58Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.88528863
59Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.86737113
60Alzheimers disease_Homo sapiens_hsa050100.84144001
61Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.82529545
62Cyanoamino acid metabolism_Homo sapiens_hsa004600.79085682
63Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.78388198
64Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.78264951
65Glutathione metabolism_Homo sapiens_hsa004800.75459977
66Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.72802657
67Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.72767829
68Sulfur metabolism_Homo sapiens_hsa009200.72348130
69Purine metabolism_Homo sapiens_hsa002300.71874044
70Fat digestion and absorption_Homo sapiens_hsa049750.71432778
71Viral myocarditis_Homo sapiens_hsa054160.70485717
72Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.70057944
73Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.69653440
74Fructose and mannose metabolism_Homo sapiens_hsa000510.68582077
75beta-Alanine metabolism_Homo sapiens_hsa004100.68462667
76Pentose and glucuronate interconversions_Homo sapiens_hsa000400.68055848
77Primary immunodeficiency_Homo sapiens_hsa053400.67890077
78Metabolic pathways_Homo sapiens_hsa011000.63542983
79Small cell lung cancer_Homo sapiens_hsa052220.63324505
80Caffeine metabolism_Homo sapiens_hsa002320.63317946
81Starch and sucrose metabolism_Homo sapiens_hsa005000.61002836
82Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.60599951
83HTLV-I infection_Homo sapiens_hsa051660.59807078
84Galactose metabolism_Homo sapiens_hsa000520.59223016
85Phototransduction_Homo sapiens_hsa047440.57312445
86Central carbon metabolism in cancer_Homo sapiens_hsa052300.56211833
87Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.55824788
88Fatty acid metabolism_Homo sapiens_hsa012120.53954546
89Measles_Homo sapiens_hsa051620.53684528
90N-Glycan biosynthesis_Homo sapiens_hsa005100.53608379
91Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.52289041
92Oocyte meiosis_Homo sapiens_hsa041140.50971472
93Apoptosis_Homo sapiens_hsa042100.49732721
94Lysine degradation_Homo sapiens_hsa003100.48626238
95Renin-angiotensin system_Homo sapiens_hsa046140.48407253
96Thyroid cancer_Homo sapiens_hsa052160.47946892
97Primary bile acid biosynthesis_Homo sapiens_hsa001200.46762002
98Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.46473099
99B cell receptor signaling pathway_Homo sapiens_hsa046620.44855067
100NF-kappa B signaling pathway_Homo sapiens_hsa040640.44317780
101Circadian rhythm_Homo sapiens_hsa047100.43675363
102Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.42268538
103Influenza A_Homo sapiens_hsa051640.40435890
104Peroxisome_Homo sapiens_hsa041460.40031995
105PPAR signaling pathway_Homo sapiens_hsa033200.39072328
106Leishmaniasis_Homo sapiens_hsa051400.38203377
107Glycerolipid metabolism_Homo sapiens_hsa005610.37667920
108HIF-1 signaling pathway_Homo sapiens_hsa040660.36800434
109Tryptophan metabolism_Homo sapiens_hsa003800.35826711
110Protein export_Homo sapiens_hsa030600.35183726
111Shigellosis_Homo sapiens_hsa051310.34729195
112Chronic myeloid leukemia_Homo sapiens_hsa052200.33403304
113Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.33091015
114MicroRNAs in cancer_Homo sapiens_hsa052060.32787989
115Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.32557420
116Arginine and proline metabolism_Homo sapiens_hsa003300.32018400
117TGF-beta signaling pathway_Homo sapiens_hsa043500.31817394
118Glycosaminoglycan degradation_Homo sapiens_hsa005310.31239850
119Toxoplasmosis_Homo sapiens_hsa051450.30913635
120mTOR signaling pathway_Homo sapiens_hsa041500.30756829
121Hepatitis B_Homo sapiens_hsa051610.30668785
122Transcriptional misregulation in cancer_Homo sapiens_hsa052020.30338980
123Glucagon signaling pathway_Homo sapiens_hsa049220.29276340
124Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.28834933
125Ether lipid metabolism_Homo sapiens_hsa005650.20291203
126Nitrogen metabolism_Homo sapiens_hsa009100.19361915
127Arginine biosynthesis_Homo sapiens_hsa002200.17464104
128Hippo signaling pathway_Homo sapiens_hsa043900.06270753
129Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.06053314
130Nicotine addiction_Homo sapiens_hsa050330.03346142
131Cardiac muscle contraction_Homo sapiens_hsa042600.01960488
132Collecting duct acid secretion_Homo sapiens_hsa049660.00143284
133Retinol metabolism_Homo sapiens_hsa008300.00024044
134Wnt signaling pathway_Homo sapiens_hsa04310-0.0188131
135Colorectal cancer_Homo sapiens_hsa05210-0.0185746

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