

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication checkpoint (GO:0000076) | 4.93101895 |
| 2 | tRNA aminoacylation for protein translation (GO:0006418) | 4.33532021 |
| 3 | amino acid activation (GO:0043038) | 4.27635040 |
| 4 | tRNA aminoacylation (GO:0043039) | 4.27635040 |
| 5 | L-serine metabolic process (GO:0006563) | 4.23784424 |
| 6 | respiratory chain complex IV assembly (GO:0008535) | 3.93440990 |
| 7 | regulation of meiosis I (GO:0060631) | 3.76536368 |
| 8 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.72291155 |
| 9 | rRNA modification (GO:0000154) | 3.66125684 |
| 10 | chromatin remodeling at centromere (GO:0031055) | 3.63870046 |
| 11 | CENP-A containing nucleosome assembly (GO:0034080) | 3.62032986 |
| 12 | DNA double-strand break processing (GO:0000729) | 3.61867382 |
| 13 | replication fork processing (GO:0031297) | 3.59750679 |
| 14 | cytochrome complex assembly (GO:0017004) | 3.55903794 |
| 15 | proteasome assembly (GO:0043248) | 3.53199627 |
| 16 | telomere maintenance via telomerase (GO:0007004) | 3.49832563 |
| 17 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.49180196 |
| 18 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.45076749 |
| 19 | tetrahydrofolate metabolic process (GO:0046653) | 3.44269359 |
| 20 | DNA deamination (GO:0045006) | 3.43888079 |
| 21 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.43375841 |
| 22 | ribosome assembly (GO:0042255) | 3.39537273 |
| 23 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.39234736 |
| 24 | purine nucleobase biosynthetic process (GO:0009113) | 3.38692369 |
| 25 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.37910182 |
| 26 | aspartate family amino acid biosynthetic process (GO:0009067) | 3.36595107 |
| 27 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.34830468 |
| 28 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.32413367 |
| 29 | nucleobase biosynthetic process (GO:0046112) | 3.28311756 |
| 30 | IMP biosynthetic process (GO:0006188) | 3.28267573 |
| 31 | histone exchange (GO:0043486) | 3.28119179 |
| 32 | regulation of centriole replication (GO:0046599) | 3.28019017 |
| 33 | meiotic chromosome segregation (GO:0045132) | 3.26825711 |
| 34 | negative regulation of DNA recombination (GO:0045910) | 3.26755111 |
| 35 | protein deneddylation (GO:0000338) | 3.26444930 |
| 36 | cullin deneddylation (GO:0010388) | 3.25470411 |
| 37 | synapsis (GO:0007129) | 3.23762192 |
| 38 | DNA strand elongation (GO:0022616) | 3.22835606 |
| 39 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.21652339 |
| 40 | rRNA methylation (GO:0031167) | 3.21165193 |
| 41 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.20722115 |
| 42 | protein-cofactor linkage (GO:0018065) | 3.20346820 |
| 43 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.14844175 |
| 44 | tRNA metabolic process (GO:0006399) | 3.13166789 |
| 45 | regulation of mitochondrial translation (GO:0070129) | 3.11714181 |
| 46 | ribonucleoprotein complex disassembly (GO:0032988) | 3.10583628 |
| 47 | serine family amino acid biosynthetic process (GO:0009070) | 3.08318885 |
| 48 | pseudouridine synthesis (GO:0001522) | 3.07808531 |
| 49 | protein complex biogenesis (GO:0070271) | 3.07495541 |
| 50 | telomere maintenance via telomere lengthening (GO:0010833) | 3.06632993 |
| 51 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.05068034 |
| 52 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.05068034 |
| 53 | nuclear pore complex assembly (GO:0051292) | 3.04334365 |
| 54 | DNA strand renaturation (GO:0000733) | 3.03862026 |
| 55 | folic acid-containing compound metabolic process (GO:0006760) | 3.02632861 |
| 56 | DNA damage response, detection of DNA damage (GO:0042769) | 3.01344949 |
| 57 | centriole replication (GO:0007099) | 3.00972231 |
| 58 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.00856168 |
| 59 | nuclear pore organization (GO:0006999) | 2.99430988 |
| 60 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.99386748 |
| 61 | DNA methylation involved in gamete generation (GO:0043046) | 2.97760078 |
| 62 | mitotic recombination (GO:0006312) | 2.96043479 |
| 63 | telomere maintenance via recombination (GO:0000722) | 2.95255010 |
| 64 | negative regulation of G2/M transition of mitotic cell cycle (GO:0010972) | 2.95017754 |
| 65 | DNA replication initiation (GO:0006270) | 2.94852000 |
| 66 | ribosome biogenesis (GO:0042254) | 2.91174461 |
| 67 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.90257146 |
| 68 | pteridine-containing compound metabolic process (GO:0042558) | 2.88454709 |
| 69 | protein K6-linked ubiquitination (GO:0085020) | 2.88434142 |
| 70 | mitochondrial RNA metabolic process (GO:0000959) | 2.87010475 |
| 71 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.86603755 |
| 72 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.86603755 |
| 73 | NADH dehydrogenase complex assembly (GO:0010257) | 2.86603755 |
| 74 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.86176420 |
| 75 | RNA-dependent DNA replication (GO:0006278) | 2.85856147 |
| 76 | organelle disassembly (GO:1903008) | 2.85600611 |
| 77 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.85248023 |
| 78 | regulation of translational fidelity (GO:0006450) | 2.84753191 |
| 79 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.83380565 |
| 80 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.83380565 |
| 81 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.83168420 |
| 82 | folic acid metabolic process (GO:0046655) | 2.83045029 |
| 83 | transcription from mitochondrial promoter (GO:0006390) | 2.82831987 |
| 84 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.80911452 |
| 85 | IMP metabolic process (GO:0046040) | 2.80863048 |
| 86 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.80297451 |
| 87 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.80297451 |
| 88 | isotype switching (GO:0045190) | 2.80297451 |
| 89 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.79994775 |
| 90 | termination of RNA polymerase III transcription (GO:0006386) | 2.79994775 |
| 91 | glutamine metabolic process (GO:0006541) | 2.77852790 |
| 92 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.77066220 |
| 93 | non-recombinational repair (GO:0000726) | 2.77066220 |
| 94 | DNA damage induced protein phosphorylation (GO:0006975) | 2.75013885 |
| 95 | tRNA processing (GO:0008033) | 2.74838349 |
| 96 | postreplication repair (GO:0006301) | 2.73372513 |
| 97 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.70697248 |
| 98 | negative regulation of translational initiation (GO:0045947) | 2.69996591 |
| 99 | negative regulation of ligase activity (GO:0051352) | 2.69784683 |
| 100 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.69784683 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.23666767 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.11302187 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.98051360 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.45368453 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.18379670 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.04934862 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.03985197 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.95740946 |
| 9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.91103903 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.86364920 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.71645228 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.69289240 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.63072784 |
| 14 | VDR_22108803_ChIP-Seq_LS180_Human | 2.51955531 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.51438609 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.45924790 |
| 17 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.44007928 |
| 18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.34050358 |
| 19 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.26162516 |
| 20 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.23684844 |
| 21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.20954055 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.08801287 |
| 23 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.08290823 |
| 24 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.02440080 |
| 25 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.99933227 |
| 26 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.98039970 |
| 27 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.98036184 |
| 28 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.92251302 |
| 29 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.91726142 |
| 30 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.90525133 |
| 31 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.87419276 |
| 32 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.84369439 |
| 33 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.80796367 |
| 34 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.80445941 |
| 35 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.70638371 |
| 36 | EWS_26573619_Chip-Seq_HEK293_Human | 1.62274625 |
| 37 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.61832031 |
| 38 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.60485046 |
| 39 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.59546380 |
| 40 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.58872165 |
| 41 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.58780953 |
| 42 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.56929820 |
| 43 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.55456173 |
| 44 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.55058024 |
| 45 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.54171752 |
| 46 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.52186785 |
| 47 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.48629850 |
| 48 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.45457376 |
| 49 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.41865789 |
| 50 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.39188419 |
| 51 | FUS_26573619_Chip-Seq_HEK293_Human | 1.36423606 |
| 52 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.33577201 |
| 53 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.32632803 |
| 54 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.31112804 |
| 55 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.25928801 |
| 56 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.23536692 |
| 57 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.20763461 |
| 58 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.18016099 |
| 59 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16761519 |
| 60 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.12877967 |
| 61 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.12765554 |
| 62 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.12046445 |
| 63 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.08123045 |
| 64 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.07745816 |
| 65 | P300_19829295_ChIP-Seq_ESCs_Human | 1.07419582 |
| 66 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.05996945 |
| 67 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.04459349 |
| 68 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.03258559 |
| 69 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.02382354 |
| 70 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.02012822 |
| 71 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.98486214 |
| 72 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.98483189 |
| 73 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.94403043 |
| 74 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.94291213 |
| 75 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.91839925 |
| 76 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.91096042 |
| 77 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.89900874 |
| 78 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.89732182 |
| 79 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.89573003 |
| 80 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.88805095 |
| 81 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.88529204 |
| 82 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.88529204 |
| 83 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.87761758 |
| 84 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.87545407 |
| 85 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.87325310 |
| 86 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.87312562 |
| 87 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.86171593 |
| 88 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.86171593 |
| 89 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.85298318 |
| 90 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.84751606 |
| 91 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.84424961 |
| 92 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.83633069 |
| 93 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.80524019 |
| 94 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.79845657 |
| 95 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.79623243 |
| 96 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.78930097 |
| 97 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.76148717 |
| 98 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.74448327 |
| 99 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.73007585 |
| 100 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.72356012 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 3.86572164 |
| 2 | MP0003890_abnormal_embryonic-extraembry | 3.41745074 |
| 3 | MP0003693_abnormal_embryo_hatching | 3.17905263 |
| 4 | MP0010094_abnormal_chromosome_stability | 3.11516417 |
| 5 | MP0002837_dystrophic_cardiac_calcinosis | 3.07698843 |
| 6 | MP0003111_abnormal_nucleus_morphology | 2.84526890 |
| 7 | MP0004957_abnormal_blastocyst_morpholog | 2.84381527 |
| 8 | MP0008932_abnormal_embryonic_tissue | 2.56051088 |
| 9 | MP0003786_premature_aging | 2.52776912 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.49190040 |
| 11 | MP0002102_abnormal_ear_morphology | 2.38014461 |
| 12 | MP0008995_early_reproductive_senescence | 2.35658501 |
| 13 | MP0003646_muscle_fatigue | 2.28983997 |
| 14 | MP0001529_abnormal_vocalization | 2.27411130 |
| 15 | MP0004147_increased_porphyrin_level | 2.25325515 |
| 16 | MP0008057_abnormal_DNA_replication | 2.11975515 |
| 17 | MP0003718_maternal_effect | 2.03835448 |
| 18 | MP0008007_abnormal_cellular_replicative | 1.98059086 |
| 19 | MP0006035_abnormal_mitochondrial_morpho | 1.93391182 |
| 20 | MP0006072_abnormal_retinal_apoptosis | 1.85967218 |
| 21 | MP0003077_abnormal_cell_cycle | 1.78434937 |
| 22 | MP0006036_abnormal_mitochondrial_physio | 1.78209735 |
| 23 | MP0001188_hyperpigmentation | 1.75174239 |
| 24 | MP0003941_abnormal_skin_development | 1.69273109 |
| 25 | MP0001661_extended_life_span | 1.66197173 |
| 26 | MP0006292_abnormal_olfactory_placode | 1.64300625 |
| 27 | MP0003195_calcinosis | 1.64057404 |
| 28 | MP0005645_abnormal_hypothalamus_physiol | 1.63515758 |
| 29 | MP0008872_abnormal_physiological_respon | 1.62620907 |
| 30 | MP0003136_yellow_coat_color | 1.54331057 |
| 31 | MP0002938_white_spotting | 1.53419210 |
| 32 | MP0005171_absent_coat_pigmentation | 1.41284772 |
| 33 | MP0002160_abnormal_reproductive_system | 1.39436856 |
| 34 | MP0002736_abnormal_nociception_after | 1.38575493 |
| 35 | MP0005410_abnormal_fertilization | 1.38160585 |
| 36 | MP0009697_abnormal_copulation | 1.34626579 |
| 37 | MP0003121_genomic_imprinting | 1.34025002 |
| 38 | MP0003119_abnormal_digestive_system | 1.32894314 |
| 39 | MP0001929_abnormal_gametogenesis | 1.28828198 |
| 40 | MP0003806_abnormal_nucleotide_metabolis | 1.27837849 |
| 41 | MP0006276_abnormal_autonomic_nervous | 1.27764847 |
| 42 | MP0002210_abnormal_sex_determination | 1.27686801 |
| 43 | MP0000372_irregular_coat_pigmentation | 1.26094175 |
| 44 | MP0003567_abnormal_fetal_cardiomyocyte | 1.17319454 |
| 45 | MP0003937_abnormal_limbs/digits/tail_de | 1.15999576 |
| 46 | MP0003122_maternal_imprinting | 1.14932821 |
| 47 | MP0009672_abnormal_birth_weight | 1.14587108 |
| 48 | MP0010307_abnormal_tumor_latency | 1.14356675 |
| 49 | MP0005389_reproductive_system_phenotype | 1.14299747 |
| 50 | MP0001730_embryonic_growth_arrest | 1.13177261 |
| 51 | MP0002751_abnormal_autonomic_nervous | 1.12125044 |
| 52 | MP0005646_abnormal_pituitary_gland | 1.11282341 |
| 53 | MP0001764_abnormal_homeostasis | 1.11184701 |
| 54 | MP0001145_abnormal_male_reproductive | 1.10280565 |
| 55 | MP0001697_abnormal_embryo_size | 1.10019219 |
| 56 | MP0000427_abnormal_hair_cycle | 1.09259351 |
| 57 | MP0000358_abnormal_cell_content/ | 1.08266191 |
| 58 | MP0003787_abnormal_imprinting | 1.07770136 |
| 59 | MP0000653_abnormal_sex_gland | 1.06699959 |
| 60 | MP0005636_abnormal_mineral_homeostasis | 1.04756777 |
| 61 | MP0009046_muscle_twitch | 1.03335541 |
| 62 | MP0001968_abnormal_touch/_nociception | 1.02103070 |
| 63 | MP0003698_abnormal_male_reproductive | 1.02002083 |
| 64 | MP0002653_abnormal_ependyma_morphology | 1.01939751 |
| 65 | MP0000647_abnormal_sebaceous_gland | 0.99507136 |
| 66 | MP0001293_anophthalmia | 0.98738120 |
| 67 | MP0005253_abnormal_eye_physiology | 0.98635260 |
| 68 | MP0002254_reproductive_system_inflammat | 0.95088681 |
| 69 | MP0002084_abnormal_developmental_patter | 0.93597711 |
| 70 | MP0003137_abnormal_impulse_conducting | 0.91710661 |
| 71 | MP0003186_abnormal_redox_activity | 0.91509680 |
| 72 | MP0005083_abnormal_biliary_tract | 0.90700038 |
| 73 | MP0005670_abnormal_white_adipose | 0.88630021 |
| 74 | MP0002132_abnormal_respiratory_system | 0.88267551 |
| 75 | MP0000631_abnormal_neuroendocrine_gland | 0.88061975 |
| 76 | MP0005084_abnormal_gallbladder_morpholo | 0.87293685 |
| 77 | MP0005332_abnormal_amino_acid | 0.87204019 |
| 78 | MP0001672_abnormal_embryogenesis/_devel | 0.85091435 |
| 79 | MP0005380_embryogenesis_phenotype | 0.85091435 |
| 80 | MP0001984_abnormal_olfaction | 0.84975491 |
| 81 | MP0002138_abnormal_hepatobiliary_system | 0.82643332 |
| 82 | MP0000350_abnormal_cell_proliferation | 0.82569787 |
| 83 | MP0010352_gastrointestinal_tract_polyps | 0.82535182 |
| 84 | MP0008875_abnormal_xenobiotic_pharmacok | 0.82380441 |
| 85 | MP0002272_abnormal_nervous_system | 0.81756134 |
| 86 | MP0001286_abnormal_eye_development | 0.81622555 |
| 87 | MP0005551_abnormal_eye_electrophysiolog | 0.81080844 |
| 88 | MP0001919_abnormal_reproductive_system | 0.78735855 |
| 89 | MP0002085_abnormal_embryonic_tissue | 0.78067608 |
| 90 | MP0005395_other_phenotype | 0.76864947 |
| 91 | MP0002080_prenatal_lethality | 0.76739103 |
| 92 | MP0009703_decreased_birth_body | 0.76481255 |
| 93 | MP0000749_muscle_degeneration | 0.75489049 |
| 94 | MP0000313_abnormal_cell_death | 0.73684539 |
| 95 | MP0001119_abnormal_female_reproductive | 0.73160033 |
| 96 | MP0004197_abnormal_fetal_growth/weight/ | 0.72497587 |
| 97 | MP0004133_heterotaxia | 0.69826572 |
| 98 | MP0002234_abnormal_pharynx_morphology | 0.65806901 |
| 99 | MP0003221_abnormal_cardiomyocyte_apopto | 0.65661155 |
| 100 | MP0003283_abnormal_digestive_organ | 0.63075238 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Cortical dysplasia (HP:0002539) | 4.53442502 |
| 2 | Abnormality of the labia minora (HP:0012880) | 4.32668717 |
| 3 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.02309291 |
| 4 | Chromsome breakage (HP:0040012) | 3.93660896 |
| 5 | Birth length less than 3rd percentile (HP:0003561) | 3.51061641 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 3.47312111 |
| 7 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.47273736 |
| 8 | Acute encephalopathy (HP:0006846) | 3.37859404 |
| 9 | Hypoplasia of the pons (HP:0012110) | 3.37106286 |
| 10 | Increased CSF lactate (HP:0002490) | 3.28786600 |
| 11 | Abnormality of the pons (HP:0007361) | 3.20288535 |
| 12 | Acanthocytosis (HP:0001927) | 3.09141446 |
| 13 | Increased hepatocellular lipid droplets (HP:0006565) | 3.07183373 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.05344085 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.01892486 |
| 16 | Abnormality of glycolysis (HP:0004366) | 2.97436695 |
| 17 | Increased serum pyruvate (HP:0003542) | 2.96737376 |
| 18 | Mitochondrial inheritance (HP:0001427) | 2.96546739 |
| 19 | Colon cancer (HP:0003003) | 2.96473732 |
| 20 | Long foot (HP:0001833) | 2.92709467 |
| 21 | Progressive macrocephaly (HP:0004481) | 2.89803418 |
| 22 | Hepatic necrosis (HP:0002605) | 2.89566045 |
| 23 | Lipid accumulation in hepatocytes (HP:0006561) | 2.84730329 |
| 24 | Abnormality of chromosome stability (HP:0003220) | 2.84397166 |
| 25 | Meckel diverticulum (HP:0002245) | 2.82602462 |
| 26 | Duodenal stenosis (HP:0100867) | 2.82132992 |
| 27 | Small intestinal stenosis (HP:0012848) | 2.82132992 |
| 28 | Abnormality of the ileum (HP:0001549) | 2.68159496 |
| 29 | Abnormality of the preputium (HP:0100587) | 2.63781936 |
| 30 | Abnormality of the duodenum (HP:0002246) | 2.54128529 |
| 31 | Short middle phalanx of the 5th finger (HP:0004220) | 2.51401907 |
| 32 | Increased serum lactate (HP:0002151) | 2.50054970 |
| 33 | Cerebral hypomyelination (HP:0006808) | 2.45007290 |
| 34 | Upper limb muscle weakness (HP:0003484) | 2.44822038 |
| 35 | Abnormality of homocysteine metabolism (HP:0010919) | 2.42345204 |
| 36 | Homocystinuria (HP:0002156) | 2.42345204 |
| 37 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.41085904 |
| 38 | Cortical visual impairment (HP:0100704) | 2.34727678 |
| 39 | Cerebral edema (HP:0002181) | 2.22193871 |
| 40 | Abnormality of alanine metabolism (HP:0010916) | 2.21911061 |
| 41 | Hyperalaninemia (HP:0003348) | 2.21911061 |
| 42 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.21911061 |
| 43 | Sloping forehead (HP:0000340) | 2.21131497 |
| 44 | Horseshoe kidney (HP:0000085) | 2.15686697 |
| 45 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.14378564 |
| 46 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.14378564 |
| 47 | Abnormal protein glycosylation (HP:0012346) | 2.14378564 |
| 48 | Abnormal glycosylation (HP:0012345) | 2.14378564 |
| 49 | Type I transferrin isoform profile (HP:0003642) | 2.13808160 |
| 50 | Duplicated collecting system (HP:0000081) | 2.12618666 |
| 51 | Aplastic anemia (HP:0001915) | 2.08452892 |
| 52 | Pendular nystagmus (HP:0012043) | 2.07241016 |
| 53 | Pancreatic cysts (HP:0001737) | 2.04233008 |
| 54 | Lactic acidosis (HP:0003128) | 2.03060499 |
| 55 | Microvesicular hepatic steatosis (HP:0001414) | 2.02654205 |
| 56 | Amelogenesis imperfecta (HP:0000705) | 2.02571076 |
| 57 | Prominent metopic ridge (HP:0005487) | 2.00634402 |
| 58 | Abnormal lung lobation (HP:0002101) | 1.98726863 |
| 59 | Abnormality of serum amino acid levels (HP:0003112) | 1.98192056 |
| 60 | Respiratory failure (HP:0002878) | 1.94825013 |
| 61 | Pancytopenia (HP:0001876) | 1.93731076 |
| 62 | Small hand (HP:0200055) | 1.90915773 |
| 63 | CNS demyelination (HP:0007305) | 1.90146876 |
| 64 | Renal Fanconi syndrome (HP:0001994) | 1.90047406 |
| 65 | Abnormality of the renal collecting system (HP:0004742) | 1.89302921 |
| 66 | Hypothermia (HP:0002045) | 1.88931696 |
| 67 | Abnormal gallbladder physiology (HP:0012438) | 1.88020966 |
| 68 | Cholecystitis (HP:0001082) | 1.88020966 |
| 69 | Postnatal microcephaly (HP:0005484) | 1.85427458 |
| 70 | Hypsarrhythmia (HP:0002521) | 1.83196022 |
| 71 | Hyperglycinemia (HP:0002154) | 1.83097112 |
| 72 | Ependymoma (HP:0002888) | 1.82524462 |
| 73 | Abnormality of the carotid arteries (HP:0005344) | 1.82229641 |
| 74 | Abnormality of glycine metabolism (HP:0010895) | 1.80374422 |
| 75 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.80374422 |
| 76 | Methylmalonic acidemia (HP:0002912) | 1.77834279 |
| 77 | Overlapping toe (HP:0001845) | 1.77624710 |
| 78 | Delayed myelination (HP:0012448) | 1.74984599 |
| 79 | Abnormality of cochlea (HP:0000375) | 1.74852051 |
| 80 | Abnormality of the metopic suture (HP:0005556) | 1.72986770 |
| 81 | Type II lissencephaly (HP:0007260) | 1.72517423 |
| 82 | Exertional dyspnea (HP:0002875) | 1.72308961 |
| 83 | Megaloblastic anemia (HP:0001889) | 1.72033904 |
| 84 | Lethargy (HP:0001254) | 1.71691830 |
| 85 | Hypomagnesemia (HP:0002917) | 1.71542633 |
| 86 | Myelodysplasia (HP:0002863) | 1.71081792 |
| 87 | Abnormal hair whorl (HP:0010721) | 1.70645392 |
| 88 | Neoplasm of the adrenal gland (HP:0100631) | 1.70339457 |
| 89 | Hypoglycemic coma (HP:0001325) | 1.70327576 |
| 90 | EEG with generalized epileptiform discharges (HP:0011198) | 1.69498836 |
| 91 | Bone marrow hypocellularity (HP:0005528) | 1.68026277 |
| 92 | Muscular hypotonia of the trunk (HP:0008936) | 1.65231944 |
| 93 | Multiple enchondromatosis (HP:0005701) | 1.65103329 |
| 94 | Patellar aplasia (HP:0006443) | 1.65009115 |
| 95 | Absent thumb (HP:0009777) | 1.64870432 |
| 96 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.64692185 |
| 97 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.63992748 |
| 98 | Abnormality of DNA repair (HP:0003254) | 1.63354483 |
| 99 | Methylmalonic aciduria (HP:0012120) | 1.62745744 |
| 100 | Ectopic kidney (HP:0000086) | 1.62192349 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 3.76501063 |
| 2 | ZAK | 3.26434539 |
| 3 | BUB1 | 3.21619802 |
| 4 | MAP4K2 | 3.02833885 |
| 5 | TTK | 2.94202490 |
| 6 | EIF2AK3 | 2.72318860 |
| 7 | LATS1 | 2.60714553 |
| 8 | TRIM28 | 2.60151169 |
| 9 | MST4 | 2.50532572 |
| 10 | PLK4 | 2.43481910 |
| 11 | STK38L | 2.22424571 |
| 12 | EIF2AK1 | 2.20735356 |
| 13 | PLK3 | 2.15121582 |
| 14 | NME1 | 2.04224160 |
| 15 | SRPK1 | 2.02071034 |
| 16 | NEK1 | 1.99628432 |
| 17 | WNK3 | 1.93099884 |
| 18 | NUAK1 | 1.92423331 |
| 19 | MKNK2 | 1.90698603 |
| 20 | BMPR1B | 1.86179148 |
| 21 | FRK | 1.85976077 |
| 22 | CDC7 | 1.83722430 |
| 23 | TNIK | 1.61746521 |
| 24 | ACVR1B | 1.57433070 |
| 25 | BRSK2 | 1.54373690 |
| 26 | PDK2 | 1.51715351 |
| 27 | BCR | 1.46693482 |
| 28 | PINK1 | 1.45335255 |
| 29 | MKNK1 | 1.40216432 |
| 30 | WNK4 | 1.38195324 |
| 31 | ADRBK2 | 1.35559706 |
| 32 | PLK1 | 1.35213455 |
| 33 | MAP3K4 | 1.28192387 |
| 34 | WEE1 | 1.20848861 |
| 35 | CSNK1G2 | 1.20099512 |
| 36 | STK3 | 1.17550926 |
| 37 | CSNK1G1 | 1.16816978 |
| 38 | PBK | 1.15902342 |
| 39 | CSNK1G3 | 1.14820871 |
| 40 | DYRK2 | 1.11426823 |
| 41 | CSNK1A1L | 1.08302972 |
| 42 | ATR | 1.07341873 |
| 43 | PLK2 | 1.03449682 |
| 44 | GRK1 | 0.96786559 |
| 45 | PASK | 0.95625197 |
| 46 | OXSR1 | 0.94660815 |
| 47 | MAP2K7 | 0.93149947 |
| 48 | CHEK2 | 0.91920897 |
| 49 | LATS2 | 0.91267539 |
| 50 | NEK2 | 0.91191314 |
| 51 | ALK | 0.88487665 |
| 52 | CLK1 | 0.86466172 |
| 53 | STK16 | 0.85621930 |
| 54 | VRK1 | 0.85457651 |
| 55 | NLK | 0.85022544 |
| 56 | CCNB1 | 0.78729399 |
| 57 | VRK2 | 0.76939411 |
| 58 | BRSK1 | 0.76297397 |
| 59 | MAP3K12 | 0.74751210 |
| 60 | ATM | 0.72482949 |
| 61 | TLK1 | 0.71981189 |
| 62 | EIF2AK2 | 0.70304393 |
| 63 | STK39 | 0.69412701 |
| 64 | CHEK1 | 0.66727037 |
| 65 | MAP3K2 | 0.65693046 |
| 66 | TGFBR1 | 0.64711344 |
| 67 | BRAF | 0.62933775 |
| 68 | CSNK1E | 0.62785505 |
| 69 | AKT3 | 0.62001938 |
| 70 | ERBB3 | 0.61502519 |
| 71 | MAPK13 | 0.59687635 |
| 72 | INSRR | 0.56606814 |
| 73 | TAF1 | 0.54702770 |
| 74 | MINK1 | 0.54558245 |
| 75 | RPS6KA4 | 0.53564951 |
| 76 | CDK3 | 0.51914998 |
| 77 | BCKDK | 0.50848462 |
| 78 | PAK3 | 0.50617762 |
| 79 | PRKCG | 0.50560095 |
| 80 | CSNK2A2 | 0.48472818 |
| 81 | CSNK2A1 | 0.46364605 |
| 82 | RPS6KA5 | 0.46122977 |
| 83 | AURKB | 0.45347527 |
| 84 | DAPK1 | 0.44003388 |
| 85 | CSNK1A1 | 0.43792588 |
| 86 | MAP3K8 | 0.43291149 |
| 87 | STK4 | 0.42298651 |
| 88 | KSR2 | 0.41908238 |
| 89 | PRKCI | 0.40753117 |
| 90 | DAPK2 | 0.39145710 |
| 91 | FGFR2 | 0.39124073 |
| 92 | CDK1 | 0.39042796 |
| 93 | CDK2 | 0.38836696 |
| 94 | KSR1 | 0.36335883 |
| 95 | PHKG1 | 0.35901933 |
| 96 | PHKG2 | 0.35901933 |
| 97 | PIK3CG | 0.35468437 |
| 98 | STK38 | 0.33988506 |
| 99 | PRKDC | 0.32779899 |
| 100 | PRKCE | 0.32102918 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 3.84660758 |
| 2 | One carbon pool by folate_Homo sapiens_hsa00670 | 3.17838902 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.05910174 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.86924086 |
| 5 | Mismatch repair_Homo sapiens_hsa03430 | 2.85549088 |
| 6 | DNA replication_Homo sapiens_hsa03030 | 2.63409439 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.53357887 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.37756656 |
| 9 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.27564850 |
| 10 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.16137699 |
| 11 | Basal transcription factors_Homo sapiens_hsa03022 | 2.15139354 |
| 12 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.11704526 |
| 13 | RNA polymerase_Homo sapiens_hsa03020 | 2.11456303 |
| 14 | RNA transport_Homo sapiens_hsa03013 | 2.10295290 |
| 15 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.04824606 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.91924319 |
| 17 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.90998520 |
| 18 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.88664877 |
| 19 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.87678515 |
| 20 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.80138946 |
| 21 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.68070850 |
| 22 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.67027813 |
| 23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.64399162 |
| 24 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.64020677 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.63202085 |
| 26 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.63017735 |
| 27 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.62718098 |
| 28 | Parkinsons disease_Homo sapiens_hsa05012 | 1.62630870 |
| 29 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.61517652 |
| 30 | Base excision repair_Homo sapiens_hsa03410 | 1.60775656 |
| 31 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.58558904 |
| 32 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.54760578 |
| 33 | Spliceosome_Homo sapiens_hsa03040 | 1.54474494 |
| 34 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.34665154 |
| 35 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.33061580 |
| 36 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.32648604 |
| 37 | Cell cycle_Homo sapiens_hsa04110 | 1.30439845 |
| 38 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.26937518 |
| 39 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26814950 |
| 40 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.24136732 |
| 41 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.22014690 |
| 42 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.20189990 |
| 43 | Huntingtons disease_Homo sapiens_hsa05016 | 1.14641584 |
| 44 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.13203498 |
| 45 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.08348758 |
| 46 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.07710087 |
| 47 | Carbon metabolism_Homo sapiens_hsa01200 | 1.02921856 |
| 48 | Nicotine addiction_Homo sapiens_hsa05033 | 1.00201869 |
| 49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.99260046 |
| 50 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.96206717 |
| 51 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.95345704 |
| 52 | Purine metabolism_Homo sapiens_hsa00230 | 0.94854900 |
| 53 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.87527846 |
| 54 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.84501586 |
| 55 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.83188762 |
| 56 | Alzheimers disease_Homo sapiens_hsa05010 | 0.82486400 |
| 57 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.76052287 |
| 58 | Metabolic pathways_Homo sapiens_hsa01100 | 0.75372903 |
| 59 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.73196262 |
| 60 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.71001516 |
| 61 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.70239941 |
| 62 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.69843310 |
| 63 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.67665876 |
| 64 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.67577234 |
| 65 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.66545008 |
| 66 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.64900407 |
| 67 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.63545709 |
| 68 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.61430790 |
| 69 | Olfactory transduction_Homo sapiens_hsa04740 | 0.58229838 |
| 70 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.55580296 |
| 71 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.53592641 |
| 72 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.53242511 |
| 73 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.51661393 |
| 74 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.50739004 |
| 75 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.49000952 |
| 76 | Sulfur relay system_Homo sapiens_hsa04122 | 0.48682463 |
| 77 | Ribosome_Homo sapiens_hsa03010 | 0.47037338 |
| 78 | Peroxisome_Homo sapiens_hsa04146 | 0.46159079 |
| 79 | Taste transduction_Homo sapiens_hsa04742 | 0.45948354 |
| 80 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.45248345 |
| 81 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.41150065 |
| 82 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.41066100 |
| 83 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.40924805 |
| 84 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.38609970 |
| 85 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.37496979 |
| 86 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.36555738 |
| 87 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.35241547 |
| 88 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.34291687 |
| 89 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.33208786 |
| 90 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.31488051 |
| 91 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.30307095 |
| 92 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.28287939 |
| 93 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.28275906 |
| 94 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.26534126 |
| 95 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.25895635 |
| 96 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.23785065 |
| 97 | GABAergic synapse_Homo sapiens_hsa04727 | 0.23678192 |
| 98 | Retinol metabolism_Homo sapiens_hsa00830 | 0.22801755 |
| 99 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.19461990 |
| 100 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.19385370 |

