

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | response to misfolded protein (GO:0051788) | 6.12826532 |
| 2 | RNA localization (GO:0006403) | 4.99023082 |
| 3 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 4.80708219 |
| 4 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 4.80708219 |
| 5 | regulation of DNA damage checkpoint (GO:2000001) | 4.64845591 |
| 6 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 4.61514155 |
| 7 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.30535193 |
| 8 | cell differentiation involved in metanephros development (GO:0072202) | 4.29957943 |
| 9 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.85672292 |
| 10 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.81527662 |
| 11 | protein neddylation (GO:0045116) | 3.79058495 |
| 12 | DNA replication checkpoint (GO:0000076) | 3.77880303 |
| 13 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.77505579 |
| 14 | protein targeting to vacuole (GO:0006623) | 3.75288680 |
| 15 | protein targeting to lysosome (GO:0006622) | 3.75288680 |
| 16 | establishment of protein localization to vacuole (GO:0072666) | 3.75288680 |
| 17 | protein-cofactor linkage (GO:0018065) | 3.70049948 |
| 18 | iron-sulfur cluster assembly (GO:0016226) | 3.69881448 |
| 19 | metallo-sulfur cluster assembly (GO:0031163) | 3.69881448 |
| 20 | DNA strand renaturation (GO:0000733) | 3.69216736 |
| 21 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.68722164 |
| 22 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.67901311 |
| 23 | positive regulation of embryonic development (GO:0040019) | 3.67768082 |
| 24 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 3.62959755 |
| 25 | UMP biosynthetic process (GO:0006222) | 3.62959755 |
| 26 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 3.62959755 |
| 27 | UMP metabolic process (GO:0046049) | 3.62959755 |
| 28 | regulation of hydrogen peroxide metabolic process (GO:0010310) | 3.54820834 |
| 29 | spermatid nucleus differentiation (GO:0007289) | 3.52769668 |
| 30 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.52493423 |
| 31 | adaptation of signaling pathway (GO:0023058) | 3.50666621 |
| 32 | positive regulation of T cell cytokine production (GO:0002726) | 3.50480825 |
| 33 | presynaptic membrane assembly (GO:0097105) | 3.47860194 |
| 34 | protein K11-linked ubiquitination (GO:0070979) | 3.44478034 |
| 35 | viral mRNA export from host cell nucleus (GO:0046784) | 3.44177049 |
| 36 | DNA ligation (GO:0006266) | 3.38420093 |
| 37 | nephron tubule morphogenesis (GO:0072078) | 3.32878580 |
| 38 | nephron epithelium morphogenesis (GO:0072088) | 3.32878580 |
| 39 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 3.31636362 |
| 40 | dopamine transport (GO:0015872) | 3.29686710 |
| 41 | oxidative demethylation (GO:0070989) | 3.27334155 |
| 42 | GMP metabolic process (GO:0046037) | 3.27123788 |
| 43 | GTP biosynthetic process (GO:0006183) | 3.27027258 |
| 44 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.24654104 |
| 45 | ATP synthesis coupled proton transport (GO:0015986) | 3.20689798 |
| 46 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.20689798 |
| 47 | regulation of male gonad development (GO:2000018) | 3.20064434 |
| 48 | UTP biosynthetic process (GO:0006228) | 3.16277254 |
| 49 | translesion synthesis (GO:0019985) | 3.15154178 |
| 50 | pyrimidine ribonucleotide biosynthetic process (GO:0009220) | 3.14179402 |
| 51 | phospholipid scrambling (GO:0017121) | 3.05227515 |
| 52 | protein K11-linked deubiquitination (GO:0035871) | 3.04610287 |
| 53 | telomere maintenance via recombination (GO:0000722) | 3.03698738 |
| 54 | DNA double-strand break processing (GO:0000729) | 3.03592680 |
| 55 | regulation of skeletal muscle contraction (GO:0014819) | 3.02795577 |
| 56 | positive regulation of meiosis (GO:0045836) | 3.02325851 |
| 57 | DNA biosynthetic process (GO:0071897) | 3.01284014 |
| 58 | negative regulation of JUN kinase activity (GO:0043508) | 2.94370002 |
| 59 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.92515511 |
| 60 | segment specification (GO:0007379) | 2.87745249 |
| 61 | transmission of nerve impulse (GO:0019226) | 2.87593325 |
| 62 | hindbrain development (GO:0030902) | 2.86551340 |
| 63 | regulation of glutamate secretion (GO:0014048) | 2.85149340 |
| 64 | regulation of glucocorticoid metabolic process (GO:0031943) | 2.83700314 |
| 65 | positive regulation of cellular response to oxidative stress (GO:1900409) | 2.82653675 |
| 66 | positive regulation of response to oxidative stress (GO:1902884) | 2.82653675 |
| 67 | positive regulation of meiotic cell cycle (GO:0051446) | 2.80650087 |
| 68 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 2.80262397 |
| 69 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.78241962 |
| 70 | CENP-A containing nucleosome assembly (GO:0034080) | 2.77997874 |
| 71 | DNA-dependent DNA replication (GO:0006261) | 2.76971977 |
| 72 | cornea development in camera-type eye (GO:0061303) | 2.75566566 |
| 73 | oocyte development (GO:0048599) | 2.74972656 |
| 74 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.72397204 |
| 75 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.71817898 |
| 76 | mitotic recombination (GO:0006312) | 2.71691777 |
| 77 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.70843603 |
| 78 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.70843603 |
| 79 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.70216226 |
| 80 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.69677035 |
| 81 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.69677035 |
| 82 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.69677035 |
| 83 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.69323301 |
| 84 | regulation of collateral sprouting (GO:0048670) | 2.68595175 |
| 85 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.68452432 |
| 86 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.68452432 |
| 87 | presynaptic membrane organization (GO:0097090) | 2.68197534 |
| 88 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 2.67720595 |
| 89 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 2.67720595 |
| 90 | negative regulation of hormone biosynthetic process (GO:0032353) | 2.67235515 |
| 91 | establishment of viral latency (GO:0019043) | 2.62297329 |
| 92 | nucleobase catabolic process (GO:0046113) | 2.62228388 |
| 93 | telomere maintenance via telomere lengthening (GO:0010833) | 2.62124620 |
| 94 | neuronal action potential propagation (GO:0019227) | 2.61304137 |
| 95 | regulation of oxidative phosphorylation (GO:0002082) | 2.61151760 |
| 96 | negative regulation of ligase activity (GO:0051352) | 2.61142483 |
| 97 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.61142483 |
| 98 | protein localization to lysosome (GO:0061462) | 2.61024661 |
| 99 | protein localization to vacuole (GO:0072665) | 2.61024661 |
| 100 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.60941326 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 4.88976361 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.45431274 |
| 3 | IRF1_19129219_ChIP-ChIP_H3396_Human | 3.40408453 |
| 4 | GATA1_22025678_ChIP-Seq_K562_Human | 3.29347665 |
| 5 | FUS_26573619_Chip-Seq_HEK293_Human | 3.16150519 |
| 6 | EWS_26573619_Chip-Seq_HEK293_Human | 3.03647955 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.81873391 |
| 8 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.56462655 |
| 9 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.54184659 |
| 10 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.38483009 |
| 11 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.36246152 |
| 12 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.28101637 |
| 13 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.26504662 |
| 14 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.18642724 |
| 15 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.14755232 |
| 16 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.14603833 |
| 17 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.99339266 |
| 18 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.99046430 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.92887413 |
| 20 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.90346626 |
| 21 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.87522804 |
| 22 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.84712967 |
| 23 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.84278388 |
| 24 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.81619910 |
| 25 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.78026927 |
| 26 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.69988487 |
| 27 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.67422993 |
| 28 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.67131280 |
| 29 | P300_19829295_ChIP-Seq_ESCs_Human | 1.57945215 |
| 30 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.57783350 |
| 31 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.54812198 |
| 32 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.52733451 |
| 33 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.51134715 |
| 34 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.50693905 |
| 35 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.46969485 |
| 36 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.45837842 |
| 37 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.45792935 |
| 38 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.43378711 |
| 39 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.39211275 |
| 40 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.35871022 |
| 41 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.35683151 |
| 42 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.35498003 |
| 43 | RXR_22108803_ChIP-Seq_LS180_Human | 1.32514526 |
| 44 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.31442831 |
| 45 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.31246143 |
| 46 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.27505145 |
| 47 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.26922065 |
| 48 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.26757898 |
| 49 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.26724633 |
| 50 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.26613158 |
| 51 | NCOR_22424771_ChIP-Seq_293T_Human | 1.26396042 |
| 52 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.25295995 |
| 53 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.22417549 |
| 54 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.21874999 |
| 55 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21742556 |
| 56 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.21516007 |
| 57 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.20305159 |
| 58 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.19179466 |
| 59 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.16661003 |
| 60 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.16551242 |
| 61 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.14224822 |
| 62 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.14224822 |
| 63 | STAT3_23295773_ChIP-Seq_U87_Human | 1.13565386 |
| 64 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.11466861 |
| 65 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.11466861 |
| 66 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.11407693 |
| 67 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.11051184 |
| 68 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.09179403 |
| 69 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.09117130 |
| 70 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 1.07244132 |
| 71 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.06270891 |
| 72 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.06040237 |
| 73 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.05867343 |
| 74 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.05664133 |
| 75 | AR_25329375_ChIP-Seq_VCAP_Human | 1.05090680 |
| 76 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.04732951 |
| 77 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.03535167 |
| 78 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.01256336 |
| 79 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.00543563 |
| 80 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.00427561 |
| 81 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.99565548 |
| 82 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.99064953 |
| 83 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.99039197 |
| 84 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.97983998 |
| 85 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.97146600 |
| 86 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.96190105 |
| 87 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.94194947 |
| 88 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.94075312 |
| 89 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.93312268 |
| 90 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.92830245 |
| 91 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.92550351 |
| 92 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.92238990 |
| 93 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.91992492 |
| 94 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.91499875 |
| 95 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.91139523 |
| 96 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.90828666 |
| 97 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.90813021 |
| 98 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.90215701 |
| 99 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.89459399 |
| 100 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.88186936 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.88307150 |
| 2 | MP0002638_abnormal_pupillary_reflex | 3.67987109 |
| 3 | MP0000569_abnormal_digit_pigmentation | 3.66216778 |
| 4 | MP0003136_yellow_coat_color | 3.02936811 |
| 5 | MP0001529_abnormal_vocalization | 3.02719942 |
| 6 | MP0000751_myopathy | 2.94365833 |
| 7 | MP0005171_absent_coat_pigmentation | 2.85838511 |
| 8 | MP0006072_abnormal_retinal_apoptosis | 2.58136455 |
| 9 | MP0001968_abnormal_touch/_nociception | 2.48097498 |
| 10 | MP0001986_abnormal_taste_sensitivity | 2.36667366 |
| 11 | MP0008058_abnormal_DNA_repair | 2.30461170 |
| 12 | MP0002837_dystrophic_cardiac_calcinosis | 2.29371641 |
| 13 | MP0004885_abnormal_endolymph | 2.18324083 |
| 14 | MP0010386_abnormal_urinary_bladder | 2.18026095 |
| 15 | MP0008875_abnormal_xenobiotic_pharmacok | 2.13031848 |
| 16 | MP0004084_abnormal_cardiac_muscle | 1.97066303 |
| 17 | MP0002653_abnormal_ependyma_morphology | 1.95065621 |
| 18 | MP0005187_abnormal_penis_morphology | 1.89596573 |
| 19 | MP0005174_abnormal_tail_pigmentation | 1.88397019 |
| 20 | MP0000778_abnormal_nervous_system | 1.81559458 |
| 21 | MP0005423_abnormal_somatic_nervous | 1.80602801 |
| 22 | MP0003880_abnormal_central_pattern | 1.75158894 |
| 23 | MP0000631_abnormal_neuroendocrine_gland | 1.68515200 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.68293841 |
| 25 | MP0002909_abnormal_adrenal_gland | 1.67564673 |
| 26 | MP0005410_abnormal_fertilization | 1.66238291 |
| 27 | MP0002736_abnormal_nociception_after | 1.65119360 |
| 28 | MP0004215_abnormal_myocardial_fiber | 1.62434422 |
| 29 | MP0005253_abnormal_eye_physiology | 1.56968871 |
| 30 | MP0002938_white_spotting | 1.55558744 |
| 31 | MP0005377_hearing/vestibular/ear_phenot | 1.55222188 |
| 32 | MP0003878_abnormal_ear_physiology | 1.55222188 |
| 33 | MP0004272_abnormal_basement_membrane | 1.54033050 |
| 34 | MP0009780_abnormal_chondrocyte_physiolo | 1.51256157 |
| 35 | MP0002272_abnormal_nervous_system | 1.50391152 |
| 36 | MP0003936_abnormal_reproductive_system | 1.46459662 |
| 37 | MP0006276_abnormal_autonomic_nervous | 1.43884646 |
| 38 | MP0000013_abnormal_adipose_tissue | 1.43856758 |
| 39 | MP0002160_abnormal_reproductive_system | 1.36589639 |
| 40 | MP0000566_synostosis | 1.36321144 |
| 41 | MP0001293_anophthalmia | 1.36023742 |
| 42 | MP0000538_abnormal_urinary_bladder | 1.35635151 |
| 43 | MP0008872_abnormal_physiological_respon | 1.30990728 |
| 44 | MP0000026_abnormal_inner_ear | 1.23253601 |
| 45 | MP0001756_abnormal_urination | 1.19170639 |
| 46 | MP0009745_abnormal_behavioral_response | 1.19161701 |
| 47 | MP0003950_abnormal_plasma_membrane | 1.16890044 |
| 48 | MP0000750_abnormal_muscle_regeneration | 1.16267918 |
| 49 | MP0003315_abnormal_perineum_morphology | 1.07921954 |
| 50 | MP0002210_abnormal_sex_determination | 1.07769213 |
| 51 | MP0003121_genomic_imprinting | 1.04422269 |
| 52 | MP0005391_vision/eye_phenotype | 1.03103677 |
| 53 | MP0005503_abnormal_tendon_morphology | 1.03061212 |
| 54 | MP0004145_abnormal_muscle_electrophysio | 1.02677478 |
| 55 | MP0000653_abnormal_sex_gland | 1.00793135 |
| 56 | MP0004484_altered_response_of | 0.99094206 |
| 57 | MP0005248_abnormal_Harderian_gland | 0.98759455 |
| 58 | MP0002067_abnormal_sensory_capabilities | 0.96896041 |
| 59 | MP0001727_abnormal_embryo_implantation | 0.95387340 |
| 60 | MP0002876_abnormal_thyroid_physiology | 0.94953496 |
| 61 | MP0003183_abnormal_peptide_metabolism | 0.94765353 |
| 62 | MP0001963_abnormal_hearing_physiology | 0.94681380 |
| 63 | MP0000955_abnormal_spinal_cord | 0.93171409 |
| 64 | MP0001929_abnormal_gametogenesis | 0.92817459 |
| 65 | MP0003123_paternal_imprinting | 0.92394148 |
| 66 | MP0001879_abnormal_lymphatic_vessel | 0.89774682 |
| 67 | MP0003111_abnormal_nucleus_morphology | 0.89487775 |
| 68 | MP0005075_abnormal_melanosome_morpholog | 0.89390412 |
| 69 | MP0001145_abnormal_male_reproductive | 0.84120310 |
| 70 | MP0001486_abnormal_startle_reflex | 0.82654555 |
| 71 | MP0008995_early_reproductive_senescence | 0.82624884 |
| 72 | MP0005195_abnormal_posterior_eye | 0.81688651 |
| 73 | MP0001502_abnormal_circadian_rhythm | 0.81517848 |
| 74 | MP0003698_abnormal_male_reproductive | 0.81154653 |
| 75 | MP0004147_increased_porphyrin_level | 0.80905270 |
| 76 | MP0003755_abnormal_palate_morphology | 0.79647991 |
| 77 | MP0002734_abnormal_mechanical_nocicepti | 0.79564612 |
| 78 | MP0000747_muscle_weakness | 0.79025550 |
| 79 | MP0002752_abnormal_somatic_nervous | 0.78813959 |
| 80 | MP0003137_abnormal_impulse_conducting | 0.78756483 |
| 81 | MP0002697_abnormal_eye_size | 0.78474032 |
| 82 | MP0001970_abnormal_pain_threshold | 0.78260800 |
| 83 | MP0004142_abnormal_muscle_tone | 0.77248518 |
| 84 | MP0005389_reproductive_system_phenotype | 0.77240757 |
| 85 | MP0000647_abnormal_sebaceous_gland | 0.75872936 |
| 86 | MP0002184_abnormal_innervation | 0.75374942 |
| 87 | MP0004858_abnormal_nervous_system | 0.74901793 |
| 88 | MP0000537_abnormal_urethra_morphology | 0.71170546 |
| 89 | MP0000639_abnormal_adrenal_gland | 0.70540807 |
| 90 | MP0009046_muscle_twitch | 0.70111297 |
| 91 | MP0003938_abnormal_ear_development | 0.69825518 |
| 92 | MP0000049_abnormal_middle_ear | 0.69331195 |
| 93 | MP0000015_abnormal_ear_pigmentation | 0.69261471 |
| 94 | MP0002234_abnormal_pharynx_morphology | 0.68975129 |
| 95 | MP0001905_abnormal_dopamine_level | 0.68722981 |
| 96 | MP0005670_abnormal_white_adipose | 0.67441183 |
| 97 | MP0001501_abnormal_sleep_pattern | 0.64415568 |
| 98 | MP0001286_abnormal_eye_development | 0.63540640 |
| 99 | MP0001324_abnormal_eye_pigmentation | 0.63495522 |
| 100 | MP0000516_abnormal_urinary_system | 0.63493422 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Amelogenesis imperfecta (HP:0000705) | 4.60112751 |
| 2 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.16981543 |
| 3 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.16981543 |
| 4 | Testicular atrophy (HP:0000029) | 3.79596816 |
| 5 | Esophageal atresia (HP:0002032) | 3.71522564 |
| 6 | Nephronophthisis (HP:0000090) | 3.43605412 |
| 7 | Fair hair (HP:0002286) | 3.43226440 |
| 8 | Hyperinsulinemic hypoglycemia (HP:0000825) | 3.42054468 |
| 9 | Abnormal sex determination (HP:0012244) | 3.41192459 |
| 10 | Sex reversal (HP:0012245) | 3.41192459 |
| 11 | J-shaped sella turcica (HP:0002680) | 3.35598471 |
| 12 | Hypoplasia of the ulna (HP:0003022) | 3.22402961 |
| 13 | Congenital stationary night blindness (HP:0007642) | 3.07505653 |
| 14 | Bony spicule pigmentary retinopathy (HP:0007737) | 3.00197513 |
| 15 | 3-Methylglutaconic aciduria (HP:0003535) | 2.99173928 |
| 16 | Facial diplegia (HP:0001349) | 2.97808066 |
| 17 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.93734964 |
| 18 | Calf muscle hypertrophy (HP:0008981) | 2.90801037 |
| 19 | Aqueductal stenosis (HP:0002410) | 2.86614588 |
| 20 | Abnormality of the renal medulla (HP:0100957) | 2.85227349 |
| 21 | Choroideremia (HP:0001139) | 2.81570522 |
| 22 | True hermaphroditism (HP:0010459) | 2.72056014 |
| 23 | Scotoma (HP:0000575) | 2.71255851 |
| 24 | Spontaneous abortion (HP:0005268) | 2.70099077 |
| 25 | Cerebral palsy (HP:0100021) | 2.60200350 |
| 26 | Muscle hypertrophy of the lower extremities (HP:0008968) | 2.56488117 |
| 27 | Chronic hepatic failure (HP:0100626) | 2.56216365 |
| 28 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.54082666 |
| 29 | Rib fusion (HP:0000902) | 2.54063506 |
| 30 | Distal lower limb muscle weakness (HP:0009053) | 2.53495015 |
| 31 | Exertional dyspnea (HP:0002875) | 2.48808355 |
| 32 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 2.44573935 |
| 33 | Pancreatic fibrosis (HP:0100732) | 2.42005751 |
| 34 | Pancreatic cysts (HP:0001737) | 2.41021086 |
| 35 | Attenuation of retinal blood vessels (HP:0007843) | 2.38170584 |
| 36 | Generalized hypopigmentation of hair (HP:0011358) | 2.34781615 |
| 37 | Hemivertebrae (HP:0002937) | 2.30997395 |
| 38 | Ulnar claw (HP:0001178) | 2.30455133 |
| 39 | Hypothermia (HP:0002045) | 2.29753391 |
| 40 | Abnormality of the calf musculature (HP:0001430) | 2.29528216 |
| 41 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.22272224 |
| 42 | Joint hemorrhage (HP:0005261) | 2.21386188 |
| 43 | Focal motor seizures (HP:0011153) | 2.21331200 |
| 44 | Round ear (HP:0100830) | 2.21122534 |
| 45 | Acute necrotizing encephalopathy (HP:0006965) | 2.20135774 |
| 46 | Abnormal number of erythroid precursors (HP:0012131) | 2.19007815 |
| 47 | Medial flaring of the eyebrow (HP:0010747) | 2.18485572 |
| 48 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.15988218 |
| 49 | Abnormality of alanine metabolism (HP:0010916) | 2.15988218 |
| 50 | Hyperalaninemia (HP:0003348) | 2.15988218 |
| 51 | Deformed sella turcica (HP:0002681) | 2.15875337 |
| 52 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.13582151 |
| 53 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.13582151 |
| 54 | Increased intramyocellular lipid droplets (HP:0012240) | 2.13015973 |
| 55 | Myotonia (HP:0002486) | 2.12619431 |
| 56 | Aplasia cutis congenita (HP:0001057) | 2.12177011 |
| 57 | Gastrointestinal atresia (HP:0002589) | 2.10180746 |
| 58 | Abnormality of the parathyroid morphology (HP:0011766) | 2.08595874 |
| 59 | Oligodactyly (HP:0012165) | 2.07373124 |
| 60 | Abnormality of dental color (HP:0011073) | 2.05935625 |
| 61 | Oligodactyly (hands) (HP:0001180) | 2.05847947 |
| 62 | Type II lissencephaly (HP:0007260) | 2.05765513 |
| 63 | Ankle clonus (HP:0011448) | 2.05075021 |
| 64 | Forearm undergrowth (HP:0009821) | 2.04851585 |
| 65 | Mitral stenosis (HP:0001718) | 2.02363360 |
| 66 | Abnormality of the fovea (HP:0000493) | 2.02342477 |
| 67 | Hyperventilation (HP:0002883) | 2.01915078 |
| 68 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.98483858 |
| 69 | Intestinal atresia (HP:0011100) | 1.98077157 |
| 70 | Chronic sinusitis (HP:0011109) | 1.97652966 |
| 71 | Progressive macrocephaly (HP:0004481) | 1.94750543 |
| 72 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.91068081 |
| 73 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.90618579 |
| 74 | External ophthalmoplegia (HP:0000544) | 1.90018943 |
| 75 | Exotropia (HP:0000577) | 1.88045378 |
| 76 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.87466743 |
| 77 | Abnormality of incisor morphology (HP:0011063) | 1.86731162 |
| 78 | Renovascular hypertension (HP:0100817) | 1.86593880 |
| 79 | Abnormality of the diencephalon (HP:0010662) | 1.85506895 |
| 80 | Molar tooth sign on MRI (HP:0002419) | 1.84008519 |
| 81 | Abnormality of midbrain morphology (HP:0002418) | 1.84008519 |
| 82 | Patellar aplasia (HP:0006443) | 1.81610561 |
| 83 | Hyporeflexia of lower limbs (HP:0002600) | 1.81475231 |
| 84 | Abnormal biliary tract physiology (HP:0012439) | 1.81006010 |
| 85 | Bile duct proliferation (HP:0001408) | 1.81006010 |
| 86 | Elfin facies (HP:0004428) | 1.80780043 |
| 87 | Synostosis involving the elbow (HP:0003938) | 1.80050609 |
| 88 | Humeroradial synostosis (HP:0003041) | 1.80050609 |
| 89 | Abnormal ciliary motility (HP:0012262) | 1.79779735 |
| 90 | Generalized aminoaciduria (HP:0002909) | 1.79055364 |
| 91 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.78517963 |
| 92 | Acute encephalopathy (HP:0006846) | 1.76716945 |
| 93 | Craniofacial dystonia (HP:0012179) | 1.76699050 |
| 94 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.76281230 |
| 95 | Progressive microcephaly (HP:0000253) | 1.75502323 |
| 96 | Gowers sign (HP:0003391) | 1.75001153 |
| 97 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.72980070 |
| 98 | Congenital malformation of the right heart (HP:0011723) | 1.72806649 |
| 99 | Double outlet right ventricle (HP:0001719) | 1.72806649 |
| 100 | Occipital encephalocele (HP:0002085) | 1.72313843 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TNIK | 3.66020305 |
| 2 | CCNB1 | 3.59418296 |
| 3 | BLK | 3.43753177 |
| 4 | EPHB2 | 2.84490412 |
| 5 | TLK1 | 2.64179595 |
| 6 | ERBB3 | 2.48766315 |
| 7 | EPHA4 | 2.43355853 |
| 8 | MKNK1 | 2.27845565 |
| 9 | MAPK15 | 2.24872295 |
| 10 | FRK | 2.24615262 |
| 11 | MKNK2 | 2.12968441 |
| 12 | PLK2 | 2.02751561 |
| 13 | WNK1 | 1.84967753 |
| 14 | MARK1 | 1.79824379 |
| 15 | PLK4 | 1.72042356 |
| 16 | SRPK1 | 1.69134810 |
| 17 | STK16 | 1.59715409 |
| 18 | GRK5 | 1.59684376 |
| 19 | WNK3 | 1.54981954 |
| 20 | WNK4 | 1.48129376 |
| 21 | VRK2 | 1.47573412 |
| 22 | ZAK | 1.47319304 |
| 23 | BMPR1B | 1.44737457 |
| 24 | CDK3 | 1.40633441 |
| 25 | MYLK | 1.31376659 |
| 26 | INSRR | 1.30937960 |
| 27 | PLK1 | 1.25627646 |
| 28 | LIMK1 | 1.24994558 |
| 29 | MUSK | 1.23535242 |
| 30 | TGFBR1 | 1.22299986 |
| 31 | BRSK2 | 1.17955244 |
| 32 | OBSCN | 1.13360530 |
| 33 | EPHA3 | 1.12492277 |
| 34 | GRK1 | 1.07910954 |
| 35 | MAP4K2 | 1.07649037 |
| 36 | MAP3K4 | 1.05891412 |
| 37 | DYRK1B | 1.05595338 |
| 38 | CSNK1G1 | 1.03875778 |
| 39 | DYRK2 | 1.03866734 |
| 40 | ADRBK2 | 1.01454635 |
| 41 | CSNK1G3 | 1.01298371 |
| 42 | DYRK1A | 0.94075904 |
| 43 | PLK3 | 0.93729582 |
| 44 | WEE1 | 0.90942366 |
| 45 | CSNK1A1L | 0.90499965 |
| 46 | FER | 0.90242890 |
| 47 | TRIM28 | 0.87209019 |
| 48 | CAMK2D | 0.84764625 |
| 49 | TIE1 | 0.79847157 |
| 50 | CSNK1A1 | 0.79334295 |
| 51 | MAPK7 | 0.78980620 |
| 52 | TNK2 | 0.78450283 |
| 53 | PKN2 | 0.74182837 |
| 54 | GRK7 | 0.73102693 |
| 55 | DAPK2 | 0.72832745 |
| 56 | PHKG1 | 0.72804812 |
| 57 | PHKG2 | 0.72804812 |
| 58 | NUAK1 | 0.72358906 |
| 59 | PASK | 0.72010791 |
| 60 | PRKD2 | 0.70647232 |
| 61 | PRKCE | 0.69173801 |
| 62 | AURKA | 0.68965874 |
| 63 | MARK2 | 0.68411267 |
| 64 | ADRBK1 | 0.68183540 |
| 65 | TESK2 | 0.67947926 |
| 66 | VRK1 | 0.65742253 |
| 67 | TRIB3 | 0.63421472 |
| 68 | CDK7 | 0.61047742 |
| 69 | CSNK1G2 | 0.60933833 |
| 70 | PKN1 | 0.59774274 |
| 71 | TAOK1 | 0.58904537 |
| 72 | PRKACB | 0.58004219 |
| 73 | MAP2K7 | 0.57892526 |
| 74 | TAOK3 | 0.54335497 |
| 75 | PIK3CA | 0.54129946 |
| 76 | PRKACA | 0.53874436 |
| 77 | PDK2 | 0.52679573 |
| 78 | PRKD3 | 0.49893301 |
| 79 | PAK3 | 0.49863769 |
| 80 | NEK6 | 0.48630344 |
| 81 | PRKACG | 0.47760535 |
| 82 | NLK | 0.47448963 |
| 83 | SIK2 | 0.46743319 |
| 84 | NTRK2 | 0.46195100 |
| 85 | NME1 | 0.45774387 |
| 86 | PTK6 | 0.43784975 |
| 87 | CHEK2 | 0.43632584 |
| 88 | PRKD1 | 0.43599493 |
| 89 | PRKCA | 0.43513598 |
| 90 | GRK6 | 0.43325622 |
| 91 | PRKG1 | 0.43103780 |
| 92 | CDK8 | 0.42990791 |
| 93 | TTK | 0.42140803 |
| 94 | CDK6 | 0.41851113 |
| 95 | SYK | 0.41675840 |
| 96 | BRSK1 | 0.41220930 |
| 97 | PRKAA1 | 0.40362783 |
| 98 | CDK11A | 0.40042184 |
| 99 | AURKB | 0.39091128 |
| 100 | INSR | 0.38975124 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.99802445 |
| 2 | Phototransduction_Homo sapiens_hsa04744 | 3.40437579 |
| 3 | Homologous recombination_Homo sapiens_hsa03440 | 3.03148238 |
| 4 | DNA replication_Homo sapiens_hsa03030 | 2.88216649 |
| 5 | Mismatch repair_Homo sapiens_hsa03430 | 2.70190326 |
| 6 | Asthma_Homo sapiens_hsa05310 | 2.57021642 |
| 7 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.53698007 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.51354294 |
| 9 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.36698606 |
| 10 | Ribosome_Homo sapiens_hsa03010 | 2.06246150 |
| 11 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.04137236 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 1.84390745 |
| 13 | Nicotine addiction_Homo sapiens_hsa05033 | 1.83726812 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 1.79753237 |
| 15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.74458382 |
| 16 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.74384341 |
| 17 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.70564887 |
| 18 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.63323128 |
| 19 | RNA polymerase_Homo sapiens_hsa03020 | 1.61474550 |
| 20 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.61275189 |
| 21 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.54059255 |
| 22 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.53610846 |
| 23 | Allograft rejection_Homo sapiens_hsa05330 | 1.47426621 |
| 24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.47235851 |
| 25 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.47113439 |
| 26 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.46360613 |
| 27 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.42468268 |
| 28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.34279871 |
| 29 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.33386297 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.31363962 |
| 31 | ABC transporters_Homo sapiens_hsa02010 | 1.28577202 |
| 32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.27527135 |
| 33 | Huntingtons disease_Homo sapiens_hsa05016 | 1.27185856 |
| 34 | Base excision repair_Homo sapiens_hsa03410 | 1.20508348 |
| 35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.15261822 |
| 36 | Taste transduction_Homo sapiens_hsa04742 | 1.10881920 |
| 37 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.09366610 |
| 38 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.05304151 |
| 39 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.05011471 |
| 40 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.02687493 |
| 41 | GABAergic synapse_Homo sapiens_hsa04727 | 1.00671639 |
| 42 | Alzheimers disease_Homo sapiens_hsa05010 | 0.97113617 |
| 43 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.96001628 |
| 44 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.95995787 |
| 45 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.95660710 |
| 46 | Spliceosome_Homo sapiens_hsa03040 | 0.93100539 |
| 47 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.92355863 |
| 48 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.90781231 |
| 49 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.90678652 |
| 50 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.90543893 |
| 51 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.89216014 |
| 52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.88054584 |
| 53 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.87987339 |
| 54 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.85953661 |
| 55 | Purine metabolism_Homo sapiens_hsa00230 | 0.83852119 |
| 56 | Morphine addiction_Homo sapiens_hsa05032 | 0.76958744 |
| 57 | Viral myocarditis_Homo sapiens_hsa05416 | 0.76549332 |
| 58 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.76485593 |
| 59 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.76478673 |
| 60 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.72131384 |
| 61 | Insulin secretion_Homo sapiens_hsa04911 | 0.70289302 |
| 62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.69141954 |
| 63 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.68789321 |
| 64 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.68122322 |
| 65 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.67637764 |
| 66 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.63943903 |
| 67 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.63038660 |
| 68 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.62838167 |
| 69 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.59901151 |
| 70 | Leishmaniasis_Homo sapiens_hsa05140 | 0.58625330 |
| 71 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.56767448 |
| 72 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.56302758 |
| 73 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.52443948 |
| 74 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.51488286 |
| 75 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.48826966 |
| 76 | Axon guidance_Homo sapiens_hsa04360 | 0.48826717 |
| 77 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.48011402 |
| 78 | Olfactory transduction_Homo sapiens_hsa04740 | 0.47913832 |
| 79 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.47893666 |
| 80 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.47622801 |
| 81 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.47292764 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.45402667 |
| 83 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.43831075 |
| 84 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.42849557 |
| 85 | Sulfur relay system_Homo sapiens_hsa04122 | 0.42648470 |
| 86 | Metabolic pathways_Homo sapiens_hsa01100 | 0.41944544 |
| 87 | Melanogenesis_Homo sapiens_hsa04916 | 0.40989036 |
| 88 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.39302474 |
| 89 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.38984790 |
| 90 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.36620395 |
| 91 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.35124522 |
| 92 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.34294345 |
| 93 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.34248598 |
| 94 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.33704049 |
| 95 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.32497401 |
| 96 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.31776665 |
| 97 | Cell cycle_Homo sapiens_hsa04110 | 0.31688940 |
| 98 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.31494686 |
| 99 | Phagosome_Homo sapiens_hsa04145 | 0.30391082 |
| 100 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.26570245 |

