ASPG

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epoxygenase P450 pathway (GO:0019373)8.85897250
2exogenous drug catabolic process (GO:0042738)8.78892964
3omega-hydroxylase P450 pathway (GO:0097267)8.76831619
4L-phenylalanine catabolic process (GO:0006559)7.66510132
5erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.66510132
6L-phenylalanine metabolic process (GO:0006558)7.31688833
7erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.31688833
8aromatic amino acid family catabolic process (GO:0009074)6.85308799
9tryptophan catabolic process (GO:0006569)6.26323477
10indole-containing compound catabolic process (GO:0042436)6.26323477
11indolalkylamine catabolic process (GO:0046218)6.26323477
12triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.19708434
13kynurenine metabolic process (GO:0070189)6.10642874
14drug metabolic process (GO:0017144)5.92912950
15tryptophan metabolic process (GO:0006568)5.88772252
16bile acid biosynthetic process (GO:0006699)5.88752631
17glyoxylate metabolic process (GO:0046487)5.79518810
18alpha-linolenic acid metabolic process (GO:0036109)5.69168875
19urea cycle (GO:0000050)5.55009828
20urea metabolic process (GO:0019627)5.55009828
21oxidative demethylation (GO:0070989)5.49288642
22regulation of plasminogen activation (GO:0010755)5.41844543
23cysteine metabolic process (GO:0006534)5.40386489
24negative regulation of fibrinolysis (GO:0051918)5.39399437
25sulfur amino acid catabolic process (GO:0000098)5.35575347
26high-density lipoprotein particle remodeling (GO:0034375)5.35515903
27regulation of protein activation cascade (GO:2000257)5.34541259
28regulation of humoral immune response (GO:0002920)5.32383628
29protein carboxylation (GO:0018214)5.29058433
30peptidyl-glutamic acid carboxylation (GO:0017187)5.29058433
31regulation of fibrinolysis (GO:0051917)5.26447848
32complement activation, alternative pathway (GO:0006957)5.24181034
33serine family amino acid catabolic process (GO:0009071)5.21139841
34nitrogen cycle metabolic process (GO:0071941)5.10230542
35bile acid metabolic process (GO:0008206)5.04767364
36aromatic amino acid family metabolic process (GO:0009072)4.98559111
37regulation of complement activation (GO:0030449)4.98410244
38fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.97779562
39acute-phase response (GO:0006953)4.90741899
40ethanol metabolic process (GO:0006067)4.85977552
41negative regulation of protein activation cascade (GO:2000258)4.85316647
42homocysteine metabolic process (GO:0050667)4.80688421
43tyrosine metabolic process (GO:0006570)4.76712736
44regulation of triglyceride catabolic process (GO:0010896)4.74915584
45alpha-amino acid catabolic process (GO:1901606)4.69915131
46lysine metabolic process (GO:0006553)4.67056405
47lysine catabolic process (GO:0006554)4.67056405
48reverse cholesterol transport (GO:0043691)4.66574506
49regulation of cholesterol esterification (GO:0010872)4.65018127
50acylglycerol homeostasis (GO:0055090)4.60828279
51triglyceride homeostasis (GO:0070328)4.60828279
52plasma lipoprotein particle remodeling (GO:0034369)4.58910233
53protein-lipid complex remodeling (GO:0034368)4.58910233
54macromolecular complex remodeling (GO:0034367)4.58910233
55negative regulation of cholesterol transport (GO:0032375)4.58592649
56negative regulation of sterol transport (GO:0032372)4.58592649
57imidazole-containing compound metabolic process (GO:0052803)4.58170704
58amino-acid betaine metabolic process (GO:0006577)4.57301960
59coenzyme catabolic process (GO:0009109)4.50243652
60glycine metabolic process (GO:0006544)4.44298080
61phospholipid efflux (GO:0033700)4.42649846
62indolalkylamine metabolic process (GO:0006586)4.42055478
63cellular ketone body metabolic process (GO:0046950)4.40388329
64bile acid and bile salt transport (GO:0015721)4.39679447
65positive regulation of fatty acid biosynthetic process (GO:0045723)4.38770375
66glutamate metabolic process (GO:0006536)4.37666751
67amine catabolic process (GO:0009310)4.33686200
68cellular biogenic amine catabolic process (GO:0042402)4.33686200
69killing of cells in other organism involved in symbiotic interaction (GO:0051883)4.32869620
70disruption of cells of other organism involved in symbiotic interaction (GO:0051818)4.32869620
71cellular amino acid catabolic process (GO:0009063)4.32370786
72positive regulation of heterotypic cell-cell adhesion (GO:0034116)4.29243348
73negative regulation of blood coagulation (GO:0030195)4.26958670
74negative regulation of hemostasis (GO:1900047)4.26958670
75serine family amino acid metabolic process (GO:0009069)4.24115993
76plasma lipoprotein particle clearance (GO:0034381)4.22743748
77cellular glucuronidation (GO:0052695)4.21354130
78cellular modified amino acid catabolic process (GO:0042219)4.18865207
79ethanol oxidation (GO:0006069)4.15862358
80benzene-containing compound metabolic process (GO:0042537)4.15135812
81phenylpropanoid metabolic process (GO:0009698)4.15010752
82S-adenosylmethionine metabolic process (GO:0046500)4.13034358
83cholesterol efflux (GO:0033344)4.10534767
84drug catabolic process (GO:0042737)4.08637792
85serine family amino acid biosynthetic process (GO:0009070)4.05908629
86dicarboxylic acid biosynthetic process (GO:0043650)4.01217387
87flavonoid metabolic process (GO:0009812)3.98365148
88negative regulation of wound healing (GO:0061045)3.95417463
89arginine metabolic process (GO:0006525)3.94449096
90fibrinolysis (GO:0042730)3.91258252
91aldehyde catabolic process (GO:0046185)3.91222684
92regulation of cholesterol homeostasis (GO:2000188)3.91184041
93negative regulation of coagulation (GO:0050819)3.88914304
94regulation of bile acid biosynthetic process (GO:0070857)3.88519544
95plasma lipoprotein particle assembly (GO:0034377)3.87727206
96alkaloid metabolic process (GO:0009820)3.86664746
97negative regulation of complement activation (GO:0045916)3.83607219
98low-density lipoprotein particle remodeling (GO:0034374)3.82663924
99ketone body metabolic process (GO:1902224)3.81111562
100acetyl-CoA metabolic process (GO:0006084)3.80150806
101cofactor catabolic process (GO:0051187)3.77957989
102organic acid catabolic process (GO:0016054)3.77002545
103carboxylic acid catabolic process (GO:0046395)3.77002545
104opsonization (GO:0008228)3.76980521
105complement activation, classical pathway (GO:0006958)3.76055679
106regulation of acute inflammatory response (GO:0002673)3.75547661
107glucuronate metabolic process (GO:0019585)3.73250940
108uronic acid metabolic process (GO:0006063)3.73250940
109blood coagulation, intrinsic pathway (GO:0007597)3.72791309
110short-chain fatty acid metabolic process (GO:0046459)3.72133576
111very-low-density lipoprotein particle assembly (GO:0034379)3.70373698
112cholesterol homeostasis (GO:0042632)3.70019975
113complement activation (GO:0006956)3.69538330
114acute inflammatory response (GO:0002526)3.69530213
115phospholipid homeostasis (GO:0055091)3.69106260
116positive regulation of triglyceride lipase activity (GO:0061365)3.68243510
117positive regulation of lipoprotein lipase activity (GO:0051006)3.68243510
118positive regulation of lipid catabolic process (GO:0050996)3.66969262
119protein activation cascade (GO:0072376)3.66364962
120sterol homeostasis (GO:0055092)3.64118521
121negative regulation of lipase activity (GO:0060192)3.63139321
122positive regulation of triglyceride metabolic process (GO:0090208)3.61806818
123cytolysis (GO:0019835)3.57235355
124NAD biosynthetic process (GO:0009435)3.56493131
125pyridine nucleotide biosynthetic process (GO:0019363)3.54494600
126nicotinamide nucleotide biosynthetic process (GO:0019359)3.54494600
127intestinal cholesterol absorption (GO:0030299)3.50573278
128positive regulation of blood coagulation (GO:0030194)3.37902409
129positive regulation of hemostasis (GO:1900048)3.37902409
130regulation of apoptotic cell clearance (GO:2000425)3.36175893
131plasma lipoprotein particle organization (GO:0071827)3.35532604
132response to mercury ion (GO:0046689)3.32191489
133regulation of triglyceride metabolic process (GO:0090207)3.28117562
134response to phenylpropanoid (GO:0080184)3.24888727
135arginine catabolic process (GO:0006527)3.17650373

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.40961248
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.23055493
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.86930853
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.49986118
5* FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.19919318
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.01521991
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.96106556
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse4.05095845
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.97377698
10TRIM28_21343339_ChIP-Seq_HEK293_Human2.85900169
11TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.08280916
12TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.03899373
13HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.00233372
14ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.9641001
15CLOCK_20551151_ChIP-Seq_293T_Human1.65621192
16FOXA2_19822575_ChIP-Seq_HepG2_Human1.60129887
17TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.52578993
18HTT_18923047_ChIP-ChIP_STHdh_Human1.49321678
19HNF4A_19822575_ChIP-Seq_HepG2_Human1.42896759
20GATA1_22025678_ChIP-Seq_K562_Human1.40744329
21THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.37376650
22TP63_17297297_ChIP-ChIP_HaCaT_Human1.30086377
23STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.24820842
24* CTCF_27219007_Chip-Seq_Bcells_Human1.22841596
25RXRA_24833708_ChIP-Seq_LIVER_Mouse1.21518117
26STAT6_21828071_ChIP-Seq_BEAS2B_Human1.18313556
27STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.16520318
28SMC4_20622854_ChIP-Seq_HELA_Human1.13429507
29ESR1_15608294_ChIP-ChIP_MCF-7_Human1.10203528
30ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.05979588
31DNAJC2_21179169_ChIP-ChIP_NT2_Human1.03294111
32DROSHA_22980978_ChIP-Seq_HELA_Human1.00482966
33IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.00008896
34SOX2_27498859_Chip-Seq_STOMACH_Mouse0.98031951
35SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97290153
36RARG_19884340_ChIP-ChIP_MEFs_Mouse0.97133346
37CTCF_20526341_ChIP-Seq_ESCs_Human0.92009243
38PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.90973422
39ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.90926565
40TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.90877846
41PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.88922653
42FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.86760226
43* E2F1_20622854_ChIP-Seq_HELA_Human0.86579870
44SA1_27219007_Chip-Seq_Bcells_Human0.85755932
45* RACK7_27058665_Chip-Seq_MCF-7_Human0.85719533
46* P68_20966046_ChIP-Seq_HELA_Human0.85502400
47TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.85034750
48AUTS2_25519132_ChIP-Seq_293T-REX_Human0.84896447
49ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.83732137
50ZNF263_19887448_ChIP-Seq_K562_Human0.83717443
51GATA4_25053715_ChIP-Seq_YYC3_Human0.83213948
52ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.82826062
53CREB1_26743006_Chip-Seq_LNCaP_Human0.81788106
54CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.81197379
55KAP1_22055183_ChIP-Seq_ESCs_Mouse0.80098559
56GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.79331287
57SRY_22984422_ChIP-ChIP_TESTIS_Rat0.78954525
58SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.77585838
59SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.77476068
60RARA_24833708_ChIP-Seq_LIVER_Mouse0.77146655
61ESR2_21235772_ChIP-Seq_MCF-7_Human0.76255220
62EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.75193141
63BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.74411743
64CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.73988691
65HNFA_21074721_ChIP-Seq_CACO-2_Human0.73757018
66* SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.73508961
67SALL4_18804426_ChIP-ChIP_XEN_Mouse0.71572765
68* BCL6_27268052_Chip-Seq_Bcells_Human0.71031703
69NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.70856148
70EZH2_27294783_Chip-Seq_ESCs_Mouse0.70647574
71RAC3_21632823_ChIP-Seq_H3396_Human0.70518680
72IRF8_22096565_ChIP-ChIP_GC-B_Human0.70350385
73CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.69899731
74GATA6_21074721_ChIP-Seq_CACO-2_Human0.69369272
75AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.69305040
76* PHF8_20622854_ChIP-Seq_HELA_Human0.69283495
77PHF8_20622853_ChIP-Seq_HELA_Human0.69051489
78NFYA_21822215_ChIP-Seq_K562_Human0.68674792
79GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.67367588
80RARB_24833708_ChIP-Seq_LIVER_Mouse0.67193296
81CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.67108430
82* BCOR_27268052_Chip-Seq_Bcells_Human0.67074176
83Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.66343404
84TET1_21451524_ChIP-Seq_MESCs_Mouse0.66338346
85SA1_27219007_Chip-Seq_ERYTHROID_Human0.66013228
86SOX2_21211035_ChIP-Seq_LN229_Human0.65963305
87RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.65218554
88SMC3_22415368_ChIP-Seq_MEFs_Mouse0.64687905
89P63_26484246_Chip-Seq_KERATINOCYTES_Human0.64284945
90BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.64076377
91NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.63952977
92STAT3_1855785_ChIP-Seq_MESCs_Mouse0.63611744
93ERA_21632823_ChIP-Seq_H3396_Human0.62482880
94RAD21_21589869_ChIP-Seq_MESCs_Mouse0.62077641
95TP63_22573176_ChIP-Seq_HFKS_Human0.61310649
96CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.61085711
97ELF1_20517297_ChIP-Seq_JURKAT_Human0.60596098
98NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.59505968
99NRF2_20460467_ChIP-Seq_MEFs_Mouse0.59505968
100* LXR_22292898_ChIP-Seq_THP-1_Human0.58896790
101CEBPB_22108803_ChIP-Seq_LS180_Human0.58573996
102E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.54894993
103MYC_19915707_ChIP-ChIP_AK7_Human0.54111353
104ESR1_21235772_ChIP-Seq_MCF-7_Human0.53428730
105* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.51094037
106FOXO3_23340844_ChIP-Seq_DLD1_Human0.51052087
107FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.50464629
108* FOXA1_25552417_ChIP-Seq_VCAP_Human0.49958207
109* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.49849343
110AR_20517297_ChIP-Seq_VCAP_Human0.49546083
111EGR1_19032775_ChIP-ChIP_M12_Human0.49341982
112CDX2_20551321_ChIP-Seq_CACO-2_Human0.48899866
113ESET_19884257_ChIP-Seq_ESCs_Mouse0.47739588
114P53_21459846_ChIP-Seq_SAOS-2_Human0.47683524
115PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.47523025
116STAT1_17558387_ChIP-Seq_HELA_Human0.46181531
117CBP_21632823_ChIP-Seq_H3396_Human0.45895781
118FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.45757097
119GATA6_25053715_ChIP-Seq_YYC3_Human0.45462849
120SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.45251395
121PPAR_26484153_Chip-Seq_NCI-H1993_Human0.44598306
122NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.44303747
123PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.44157314
124TAF2_19829295_ChIP-Seq_ESCs_Human0.43991386
125ERG_21242973_ChIP-ChIP_JURKAT_Human0.43653172
126PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.41006603
127STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.40845945
128GATA1_19941826_ChIP-Seq_K562_Human0.40277379
129ESR1_20079471_ChIP-ChIP_T-47D_Human0.40037986
130MYC_27129775_Chip-Seq_CORNEA_Mouse0.39600269
131BCAT_22108803_ChIP-Seq_LS180_Human0.38423206
132CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.37839649
133GATA1_19941827_ChIP-Seq_MEL_Mouse0.37225124
134GATA2_19941826_ChIP-Seq_K562_Human0.36595610
135CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.36132968
136FOXH1_21741376_ChIP-Seq_EPCs_Human0.35074350
137GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.34926548
138LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.34721841
139NCOR_22424771_ChIP-Seq_293T_Human0.34504675
140SPI1_26923725_Chip-Seq_HPCs_Mouse0.34441213
141GATA3_24758297_ChIP-Seq_MCF-7_Human0.34336250
142SOX3_22085726_ChIP-Seq_MUSCLE_Mouse0.34125484
143MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.34069304
144P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.33955007

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.31265823
2MP0005360_urolithiasis7.46705391
3MP0005085_abnormal_gallbladder_physiolo6.43166164
4MP0005365_abnormal_bile_salt6.10683425
5MP0008875_abnormal_xenobiotic_pharmacok5.15807366
6MP0003806_abnormal_nucleotide_metabolis4.24760662
7MP0003252_abnormal_bile_duct3.97393851
8MP0010329_abnormal_lipoprotein_level3.59619531
9MP0009840_abnormal_foam_cell3.24812708
10MP0005083_abnormal_biliary_tract3.04593490
11MP0003195_calcinosis2.93512105
12MP0005332_abnormal_amino_acid2.83266373
13MP0001666_abnormal_nutrient_absorption2.60211434
14MP0003191_abnormal_cellular_cholesterol2.31351936
15MP0004019_abnormal_vitamin_homeostasis2.19955578
16MP0000609_abnormal_liver_physiology2.18729704
17MP0002118_abnormal_lipid_homeostasis2.14201871
18MP0002138_abnormal_hepatobiliary_system1.93313596
19MP0005319_abnormal_enzyme/_coenzyme1.83462062
20MP0003868_abnormal_feces_composition1.80247089
21MP0001764_abnormal_homeostasis1.60563782
22MP0005584_abnormal_enzyme/coenzyme_acti1.56272912
23MP0005451_abnormal_body_composition1.54343884
24MP0009697_abnormal_copulation1.43748625
25MP0003011_delayed_dark_adaptation1.28732748
26MP0009643_abnormal_urine_homeostasis1.28587819
27MP0003705_abnormal_hypodermis_morpholog1.23060615
28MP0003186_abnormal_redox_activity1.22516831
29MP0002254_reproductive_system_inflammat1.22158147
30MP0003656_abnormal_erythrocyte_physiolo1.19212066
31MP0000598_abnormal_liver_morphology1.17915100
32MP0005647_abnormal_sex_gland1.15719181
33MP0002249_abnormal_larynx_morphology1.11711817
34MP0003879_abnormal_hair_cell1.11458660
35MP0000566_synostosis1.08927022
36MP0000604_amyloidosis1.08153564
37MP0002332_abnormal_exercise_endurance1.04631157
38MP0009764_decreased_sensitivity_to1.03221252
39MP0002282_abnormal_trachea_morphology1.00972198
40MP0009763_increased_sensitivity_to0.99554674
41MP0010368_abnormal_lymphatic_system0.98358222
42MP0005636_abnormal_mineral_homeostasis0.96934793
43MP0005670_abnormal_white_adipose0.90818176
44MP0002132_abnormal_respiratory_system0.90398314
45MP0009642_abnormal_blood_homeostasis0.87437190
46MP0008469_abnormal_protein_level0.86241281
47MP0006036_abnormal_mitochondrial_physio0.83205719
48MP0002971_abnormal_brown_adipose0.81757238
49MP0005408_hypopigmentation0.80153745
50MP0000467_abnormal_esophagus_morphology0.80089587
51MP0002876_abnormal_thyroid_physiology0.78444647
52MP0005376_homeostasis/metabolism_phenot0.78355227
53MP0002078_abnormal_glucose_homeostasis0.78223643
54MP0005084_abnormal_gallbladder_morpholo0.77233791
55MP0009765_abnormal_xenobiotic_induced0.74051388
56MP0004084_abnormal_cardiac_muscle0.74006832
57MP0005220_abnormal_exocrine_pancreas0.73178605
58MP0005334_abnormal_fat_pad0.73123245
59MP0001661_extended_life_span0.72740911
60MP0004130_abnormal_muscle_cell0.72176351
61MP0005330_cardiomyopathy0.71413543
62MP0006138_congestive_heart_failure0.68633644
63MP0005535_abnormal_body_temperature0.68271333
64MP0003690_abnormal_glial_cell0.66047881
65MP0008775_abnormal_heart_ventricle0.66008634
66MP0005266_abnormal_metabolism0.65262247
67MP0001756_abnormal_urination0.65126022
68MP0003329_amyloid_beta_deposits0.64645609
69MP0009053_abnormal_anal_canal0.61370473
70MP0002234_abnormal_pharynx_morphology0.60851716
71MP0005167_abnormal_blood-brain_barrier0.59326843
72MP0005595_abnormal_vascular_smooth0.58911134
73MP0006035_abnormal_mitochondrial_morpho0.58410378
74MP0005448_abnormal_energy_balance0.57152450
75MP0000639_abnormal_adrenal_gland0.55815818
76MP0000678_abnormal_parathyroid_gland0.53840653
77MP0005187_abnormal_penis_morphology0.52254207
78MP0005023_abnormal_wound_healing0.52110992
79MP0005395_other_phenotype0.51375784
80MP0002136_abnormal_kidney_physiology0.51079920
81MP0001986_abnormal_taste_sensitivity0.49909254
82MP0003718_maternal_effect0.49795223
83MP0003878_abnormal_ear_physiology0.48761552
84MP0005377_hearing/vestibular/ear_phenot0.48761552
85MP0003638_abnormal_response/metabolism_0.48013369
86MP0005464_abnormal_platelet_physiology0.47754432
87MP0002089_abnormal_postnatal_growth/wei0.47573422
88MP0004036_abnormal_muscle_relaxation0.47483466
89MP0005409_darkened_coat_color0.47383807
90MP0002822_catalepsy0.47037765
91MP0003724_increased_susceptibility_to0.46366518
92MP0002928_abnormal_bile_duct0.46255672
93MP0005666_abnormal_adipose_tissue0.45913186
94MP0010630_abnormal_cardiac_muscle0.45815000
95MP0001544_abnormal_cardiovascular_syste0.45804127
96MP0005385_cardiovascular_system_phenoty0.45804127
97MP0008874_decreased_physiological_sensi0.44168043
98MP0002837_dystrophic_cardiac_calcinosis0.44007290
99MP0003953_abnormal_hormone_level0.42554838
100MP0008873_increased_physiological_sensi0.42158963
101MP0009384_cardiac_valve_regurgitation0.41226287
102MP0003436_decreased_susceptibility_to0.40084592
103MP0005166_decreased_susceptibility_to0.40060022
104MP0009785_altered_susceptibility_to0.39665680
105MP0004215_abnormal_myocardial_fiber0.39494401
106MP0005375_adipose_tissue_phenotype0.38696956
107MP0003075_altered_response_to0.38502676
108MP0000579_abnormal_nail_morphology0.38474355
109MP0002796_impaired_skin_barrier0.38314838
110MP0001915_intracranial_hemorrhage0.38178697
111MP0000751_myopathy0.37849566
112MP0004782_abnormal_surfactant_physiolog0.37682559
113MP0009672_abnormal_birth_weight0.37604049
114MP0005248_abnormal_Harderian_gland0.36953354
115MP0002128_abnormal_blood_circulation0.36614827
116MP0008872_abnormal_physiological_respon0.36227305
117MP0002098_abnormal_vibrissa_morphology0.35847450
118MP0009115_abnormal_fat_cell0.35593229
119MP0002970_abnormal_white_adipose0.34387895
120MP0002168_other_aberrant_phenotype0.34353921
121MP0004381_abnormal_hair_follicle0.34180266
122MP0000230_abnormal_systemic_arterial0.33970099
123MP0006082_CNS_inflammation0.33483968
124MP0001881_abnormal_mammary_gland0.31493295
125MP0000249_abnormal_blood_vessel0.31463309
126MP0001243_abnormal_dermal_layer0.30088562
127MP0004883_abnormal_blood_vessel0.28912015
128MP0005058_abnormal_lysosome_morphology0.28657340
129MP0002060_abnormal_skin_morphology0.26773760
130MP0001853_heart_inflammation0.26431609
131MP0004264_abnormal_extraembryonic_tissu0.26151771
132MP0001845_abnormal_inflammatory_respons0.25099840
133MP0010234_abnormal_vibrissa_follicle0.25019588

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.44148796
2Deep venous thrombosis (HP:0002625)7.24921763
3Intrahepatic cholestasis (HP:0001406)7.22726426
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.64632014
5Prolonged partial thromboplastin time (HP:0003645)6.43028686
6Hypobetalipoproteinemia (HP:0003563)6.31365814
7Xanthomatosis (HP:0000991)6.22576337
8Hyperlipoproteinemia (HP:0010980)5.57880122
9Complement deficiency (HP:0004431)5.25338274
10Hypolipoproteinemia (HP:0010981)4.71341388
11Joint hemorrhage (HP:0005261)4.64681702
12Hyperglycinemia (HP:0002154)4.60646810
13Hyperammonemia (HP:0001987)4.59975537
14Epidermoid cyst (HP:0200040)4.51401469
15Abnormality of the common coagulation pathway (HP:0010990)4.40752306
16Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.30027260
17Ketosis (HP:0001946)4.29911257
18Nephritis (HP:0000123)4.26196641
19Abnormality of sulfur amino acid metabolism (HP:0004339)4.23522215
20Abnormality of glutamine family amino acid metabolism (HP:0010902)4.20190224
21Abnormality of methionine metabolism (HP:0010901)4.17940895
22Hypoalphalipoproteinemia (HP:0003233)4.17149343
23Hyperglycinuria (HP:0003108)4.17112593
24Abnormality of glycine metabolism (HP:0010895)4.11924552
25Abnormality of serine family amino acid metabolism (HP:0010894)4.11924552
26Abnormality of aspartate family amino acid metabolism (HP:0010899)4.08051629
27Fat malabsorption (HP:0002630)4.03553130
28Hypoglycemic coma (HP:0001325)3.87694989
29Abnormality of complement system (HP:0005339)3.81932375
30Conjugated hyperbilirubinemia (HP:0002908)3.76508397
31Abnormality of pyrimidine metabolism (HP:0004353)3.71615315
32Abnormality of the intrinsic pathway (HP:0010989)3.67682935
33Hypercholesterolemia (HP:0003124)3.60595267
34Abnormality of fatty-acid metabolism (HP:0004359)3.36690436
35Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.34778973
36Hyperbilirubinemia (HP:0002904)3.28198106
37Spontaneous abortion (HP:0005268)3.25331360
38Myocardial infarction (HP:0001658)3.17175646
39Delayed CNS myelination (HP:0002188)3.10458983
40Abnormality of serum amino acid levels (HP:0003112)3.10095492
41Abnormality of nucleobase metabolism (HP:0010932)3.08624174
42Ketoacidosis (HP:0001993)3.07585251
43Steatorrhea (HP:0002570)3.01420090
44Hepatocellular carcinoma (HP:0001402)2.92954516
45Neonatal hypoglycemia (HP:0001998)2.91870721
46Hypochromic microcytic anemia (HP:0004840)2.81588627
47Skin nodule (HP:0200036)2.80757907
48Systemic lupus erythematosus (HP:0002725)2.79533765
49Abnormality of purine metabolism (HP:0004352)2.77128604
50Metabolic acidosis (HP:0001942)2.75624815
51Vascular calcification (HP:0004934)2.73068013
52Fair hair (HP:0002286)2.65267302
53Dicarboxylic aciduria (HP:0003215)2.63845403
54Abnormality of dicarboxylic acid metabolism (HP:0010995)2.63845403
55Gout (HP:0001997)2.63624530
56Lethargy (HP:0001254)2.60590742
57Mitral stenosis (HP:0001718)2.51897977
58Malnutrition (HP:0004395)2.50050671
59Spastic diplegia (HP:0001264)2.48991804
60Hypoglycemic seizures (HP:0002173)2.47912592
61Abnormal gallbladder morphology (HP:0012437)2.44800892
62Cardiovascular calcification (HP:0011915)2.42806414
63Acanthocytosis (HP:0001927)2.40839292
64Cholelithiasis (HP:0001081)2.39239458
65Irritability (HP:0000737)2.37311974
66Glomerulonephritis (HP:0000099)2.36042900
67Cerebral edema (HP:0002181)2.33432467
68Neonatal onset (HP:0003623)2.33049606
69Cholecystitis (HP:0001082)2.29026546
70Abnormal gallbladder physiology (HP:0012438)2.29026546
71Cerebral palsy (HP:0100021)2.28436376
72Amyloidosis (HP:0011034)2.27883687
73Osteomalacia (HP:0002749)2.24457395
74Gingival bleeding (HP:0000225)2.20623005
75Sensorimotor neuropathy (HP:0007141)2.19481134
76Esophageal varix (HP:0002040)2.18185668
77Atrioventricular block (HP:0001678)2.17772089
78Late onset (HP:0003584)2.17197084
79Brushfield spots (HP:0001088)2.17020619
80Purpura (HP:0000979)2.15565785
81Joint swelling (HP:0001386)2.13752969
82Recurrent gram-negative bacterial infections (HP:0005420)2.11791945
83Enlarged kidneys (HP:0000105)2.11602862
84Pancreatitis (HP:0001733)2.11256416
85Hemorrhage of the eye (HP:0011885)2.11224783
86Vomiting (HP:0002013)2.09752308
87Thrombophlebitis (HP:0004418)2.09020557
88Menorrhagia (HP:0000132)2.06273622
89Generalized aminoaciduria (HP:0002909)2.05151514
90Abnormality of the Achilles tendon (HP:0005109)2.04813414
91Opisthotonus (HP:0002179)2.03739563
92Hyperinsulinemic hypoglycemia (HP:0000825)2.02352154
93Rickets (HP:0002748)2.02304361
94Hydroxyprolinuria (HP:0003080)2.01814020
95Abnormality of proline metabolism (HP:0010907)2.01814020
96Abnormality of the gallbladder (HP:0005264)2.00147746
97Hypophosphatemic rickets (HP:0004912)2.00020257
98Generalized hypopigmentation of hair (HP:0011358)1.96894563
99Abnormal cartilage morphology (HP:0002763)1.96355553
100Arthropathy (HP:0003040)1.94858848
101Poikilocytosis (HP:0004447)1.94472810
102Abnormality of iron homeostasis (HP:0011031)1.93952068
103Abnormality of transition element cation homeostasis (HP:0011030)1.92200819
104Pulmonary embolism (HP:0002204)1.91516180
105Alkalosis (HP:0001948)1.88553856
106Elevated alkaline phosphatase (HP:0003155)1.85775098
107Blue irides (HP:0000635)1.84285686
108Abnormal enzyme/coenzyme activity (HP:0012379)1.81218775
109Renal cortical cysts (HP:0000803)1.80617638
110Status epilepticus (HP:0002133)1.80472500
111Elevated hepatic transaminases (HP:0002910)1.79534674
112Hyperuricemia (HP:0002149)1.78005462
113Increased purine levels (HP:0004368)1.78005462
114Hyperglycemia (HP:0003074)1.76773455
115Abnormality of alkaline phosphatase activity (HP:0004379)1.71242418
116Increased serum ferritin (HP:0003281)1.70232597
117Retinal atrophy (HP:0001105)1.64314831
118Lymphangioma (HP:0100764)1.61547265
119Gangrene (HP:0100758)1.61006017
120Epistaxis (HP:0000421)1.60682200
121Heart block (HP:0012722)1.59219870
122Abnormal delivery (HP:0001787)1.56555635
123Focal segmental glomerulosclerosis (HP:0000097)1.55658888
124Abnormal atrioventricular conduction (HP:0005150)1.55639301
125Increased mean platelet volume (HP:0011877)1.52355249
126Facial shape deformation (HP:0011334)1.52296054
127Potter facies (HP:0002009)1.52296054
128Back pain (HP:0003418)1.49722020
129Abnormal platelet function (HP:0011869)1.44130814

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.94925992
2FGFR44.84494509
3SIK14.76231880
4ERN14.46213193
5NTRK33.58571818
6TAOK33.06846319
7ERBB43.01055455
8INSRR2.97432819
9MUSK2.56362531
10MYLK2.55801818
11MAP2K42.16159562
12PKN22.15958296
13MST1R2.15025074
14PIK3CA2.13785470
15TRIB31.90843529
16MAPK111.89161919
17FLT31.78780770
18MAPKAPK31.78459430
19PIK3CG1.77530017
20TYK21.76411660
21LATS11.75647545
22PTK61.59753480
23NLK1.55434776
24DAPK21.52960534
25EPHA21.49030915
26FGFR21.41590880
27ABL21.40243585
28DMPK1.38694710
29MAP3K71.31454097
30FRK1.29459919
31NEK91.28470140
32KDR1.28390201
33JAK21.24021284
34FER1.22629561
35PRKAA21.21874092
36CDC42BPA1.14116688
37MAPK151.11889374
38PINK11.10540519
39TNK21.10282431
40ERBB21.07889608
41STK38L1.02304764
42JAK11.01937238
43PDK21.01313929
44MAP3K101.01213805
45MAP2K31.00494768
46GRK60.97418222
47TBK10.96103604
48MAPK40.92665085
49MAP3K140.91117853
50TTN0.89574355
51PRKCZ0.89377898
52CAMK1D0.89160369
53MET0.88065776
54RPS6KA20.86297843
55SMG10.84653252
56EPHB10.84412195
57RPS6KL10.84314105
58RPS6KC10.84314105
59RPS6KA60.81785778
60CDK60.80411813
61PRKD20.80369662
62MAP3K30.77518973
63TIE10.75129213
64MAPK120.74735610
65DYRK1B0.74012741
66SIK20.73878203
67PRKACG0.73847168
68PRKAA10.73777252
69DAPK30.73418811
70PRKACA0.73212334
71TGFBR20.72354403
72EEF2K0.72165879
73BMPR1B0.71572744
74CAMK2G0.71260063
75EPHA30.70196613
76GSK3A0.69630655
77MARK20.68962286
78STK380.68781800
79SGK30.67777612
80CSK0.67403227
81IRAK30.66520745
82MAP2K60.65575220
83EPHB20.65004520
84TGFBR10.63532992
85PTK20.63159900
86MAP3K110.63154099
87RIPK10.62131000
88MAP3K20.61150438
89PRPF4B0.59520722
90FGFR30.58799203
91PDPK10.56835775
92ACVR1B0.55666369
93PRKD10.54375868
94MAPK70.50413880
95PRKG10.50131082
96CSNK1G10.49651753
97ROCK10.49173813
98SGK20.47906524
99MAP3K60.47098544
100STK110.46853972
101ICK0.46064105
102EPHA40.46046942
103MAP3K130.45954919
104MTOR0.44333383
105AKT30.42811559
106IKBKE0.42797235
107PDK30.42127620
108PDK40.42127620
109PRKCQ0.41727988
110CDK40.41725526
111CAMK1G0.41387597
112OBSCN0.40557360
113CSF1R0.40093797
114MAP2K10.39916657
115PRKCE0.39708268
116RPS6KA30.39285471
117PDGFRB0.38990738
118IGF1R0.38940760
119LATS20.38706503
120TAOK20.37524745
121RET0.36342506
122SGK2230.36092126
123SGK4940.36092126
124PKN10.35743021
125PRKCG0.34179230
126GRK10.33869576
127PDK10.31565454
128MAP3K50.31055833
129MAP3K10.29315334
130EGFR0.29232692
131CAMK40.28541005
132CSNK1G20.27312214
133MAP2K20.25477498
134PRKCA0.24500186
135CSNK1G30.24306357
136PAK30.24059340
137BMX0.23307909
138PDGFRA0.22669901
139IRAK20.22380392

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.44489009
2Nitrogen metabolism_Homo sapiens_hsa009103.53047037
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.33809625
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.28764113
5Arginine biosynthesis_Homo sapiens_hsa002203.02238422
6Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.73681367
7Complement and coagulation cascades_Homo sapiens_hsa046102.72067568
8Tryptophan metabolism_Homo sapiens_hsa003802.70804580
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.67931477
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.55721171
11Fatty acid degradation_Homo sapiens_hsa000712.52522401
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.41259645
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.27709560
14Butanoate metabolism_Homo sapiens_hsa006502.18944309
15Peroxisome_Homo sapiens_hsa041462.09629318
16Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.09466309
17Propanoate metabolism_Homo sapiens_hsa006401.95925541
18Histidine metabolism_Homo sapiens_hsa003401.95546000
19Chemical carcinogenesis_Homo sapiens_hsa052041.91620216
20PPAR signaling pathway_Homo sapiens_hsa033201.90927223
21Steroid hormone biosynthesis_Homo sapiens_hsa001401.88845613
22Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.87822299
23Fatty acid metabolism_Homo sapiens_hsa012121.84678453
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.78198709
25Staphylococcus aureus infection_Homo sapiens_hsa051501.74955795
26Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.73260865
27Caffeine metabolism_Homo sapiens_hsa002321.72460742
28Retinol metabolism_Homo sapiens_hsa008301.70240739
29beta-Alanine metabolism_Homo sapiens_hsa004101.70004479
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.66655684
31Selenocompound metabolism_Homo sapiens_hsa004501.61301962
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.58826284
332-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.57024441
34Phenylalanine metabolism_Homo sapiens_hsa003601.52127927
35Bile secretion_Homo sapiens_hsa049761.51455143
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.44843788
37Tyrosine metabolism_Homo sapiens_hsa003501.43301118
38Pyruvate metabolism_Homo sapiens_hsa006201.40596510
39Sulfur metabolism_Homo sapiens_hsa009201.32563027
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.31702426
41Fatty acid elongation_Homo sapiens_hsa000621.29822273
42Starch and sucrose metabolism_Homo sapiens_hsa005001.26623683
43ABC transporters_Homo sapiens_hsa020101.23296611
44Folate biosynthesis_Homo sapiens_hsa007901.23157663
45Biosynthesis of amino acids_Homo sapiens_hsa012301.20831497
46Steroid biosynthesis_Homo sapiens_hsa001001.17115283
47Carbon metabolism_Homo sapiens_hsa012001.15454013
48Fat digestion and absorption_Homo sapiens_hsa049751.15012488
49Cyanoamino acid metabolism_Homo sapiens_hsa004601.10671429
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.06581245
51Vitamin B6 metabolism_Homo sapiens_hsa007501.06297696
52Maturity onset diabetes of the young_Homo sapiens_hsa049501.00778125
53Arginine and proline metabolism_Homo sapiens_hsa003300.97176938
54Sulfur relay system_Homo sapiens_hsa041220.94117271
55Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.94082571
56Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.91539242
57Vitamin digestion and absorption_Homo sapiens_hsa049770.86799133
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.84901345
59Lysine degradation_Homo sapiens_hsa003100.84138006
60One carbon pool by folate_Homo sapiens_hsa006700.79347699
61Glycerolipid metabolism_Homo sapiens_hsa005610.71682409
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.70839464
63Glutathione metabolism_Homo sapiens_hsa004800.66456057
64Pentose phosphate pathway_Homo sapiens_hsa000300.57706306
65Fatty acid biosynthesis_Homo sapiens_hsa000610.57345312
66Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.53678885
67Metabolic pathways_Homo sapiens_hsa011000.46513839
68Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.41983756
69Pertussis_Homo sapiens_hsa051330.35008483
70Prion diseases_Homo sapiens_hsa050200.32651233
71alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.30558172
72Galactose metabolism_Homo sapiens_hsa000520.26694101
73Insulin resistance_Homo sapiens_hsa049310.25460213
74Fructose and mannose metabolism_Homo sapiens_hsa000510.24791063
75Adipocytokine signaling pathway_Homo sapiens_hsa049200.24588603
76Linoleic acid metabolism_Homo sapiens_hsa005910.20693779
77Glycerophospholipid metabolism_Homo sapiens_hsa005640.20654167
78Other glycan degradation_Homo sapiens_hsa005110.18689690
79Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.17064861
80Glucagon signaling pathway_Homo sapiens_hsa049220.13095648
81Vascular smooth muscle contraction_Homo sapiens_hsa042700.08444251
82AMPK signaling pathway_Homo sapiens_hsa041520.04064955
83Serotonergic synapse_Homo sapiens_hsa047260.03950475
84Mineral absorption_Homo sapiens_hsa049780.01644099
85Amoebiasis_Homo sapiens_hsa05146-0.2382126
86Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2285728
87Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2273468
88Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.2238755
89Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2188580
90Renin-angiotensin system_Homo sapiens_hsa04614-0.2041907
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1996383
92Bladder cancer_Homo sapiens_hsa05219-0.1985454
93Cocaine addiction_Homo sapiens_hsa05030-0.1946286
94Aldosterone synthesis and secretion_Homo sapiens_hsa04925-0.1809599
95Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1800597
96Dilated cardiomyopathy_Homo sapiens_hsa05414-0.1790652
97African trypanosomiasis_Homo sapiens_hsa05143-0.1769800
98Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1699566
99Hepatitis C_Homo sapiens_hsa05160-0.1697578
100TGF-beta signaling pathway_Homo sapiens_hsa04350-0.1642238
101Ether lipid metabolism_Homo sapiens_hsa00565-0.1570125
102Sphingolipid metabolism_Homo sapiens_hsa00600-0.1464057
103Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1456903
104Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1295638
105Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1114854
106Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1078780
107Regulation of autophagy_Homo sapiens_hsa04140-0.1044070
108Circadian rhythm_Homo sapiens_hsa04710-0.0918196
109Insulin signaling pathway_Homo sapiens_hsa04910-0.0850964
110Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0714419
111Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0683250
112Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0469050

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