ASPHD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.76547686
2positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.59500012
3vocalization behavior (GO:0071625)5.37421112
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.35380169
5locomotory exploration behavior (GO:0035641)5.29230274
6synaptic vesicle exocytosis (GO:0016079)5.06250936
7synaptic vesicle maturation (GO:0016188)5.02023224
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.00978059
9ionotropic glutamate receptor signaling pathway (GO:0035235)5.00137817
10protein localization to synapse (GO:0035418)4.95789567
11regulation of glutamate receptor signaling pathway (GO:1900449)4.93327766
12neuron cell-cell adhesion (GO:0007158)4.89028002
13histone arginine methylation (GO:0034969)4.74516212
14regulation of synaptic vesicle exocytosis (GO:2000300)4.70474968
15glutamate secretion (GO:0014047)4.55267327
16neuronal action potential propagation (GO:0019227)4.55105270
17glutamate receptor signaling pathway (GO:0007215)4.54310190
18regulation of neuronal synaptic plasticity (GO:0048168)4.51534027
19regulation of long-term neuronal synaptic plasticity (GO:0048169)4.48354142
20synaptic transmission, glutamatergic (GO:0035249)4.44291134
21potassium ion homeostasis (GO:0055075)4.27317525
22synaptic vesicle docking involved in exocytosis (GO:0016081)4.26084440
23exploration behavior (GO:0035640)4.24691087
24regulation of synaptic vesicle transport (GO:1902803)4.21664014
25neurotransmitter-gated ion channel clustering (GO:0072578)4.19387837
26neuron-neuron synaptic transmission (GO:0007270)4.18572172
27dendritic spine morphogenesis (GO:0060997)4.15347106
28regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.12296529
29regulation of synapse structural plasticity (GO:0051823)4.06574802
30regulation of excitatory postsynaptic membrane potential (GO:0060079)4.05060942
31neurotransmitter secretion (GO:0007269)4.03038146
32long-term memory (GO:0007616)3.99464298
33transmission of nerve impulse (GO:0019226)3.99453486
34regulation of dendritic spine morphogenesis (GO:0061001)3.97910103
35layer formation in cerebral cortex (GO:0021819)3.96630581
36neuron recognition (GO:0008038)3.95152829
37positive regulation of synapse maturation (GO:0090129)3.84949510
38regulation of postsynaptic membrane potential (GO:0060078)3.82307358
39positive regulation of membrane potential (GO:0045838)3.75709622
40membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.74677813
41axonal fasciculation (GO:0007413)3.73110369
42regulation of synaptic plasticity (GO:0048167)3.71571436
43gamma-aminobutyric acid transport (GO:0015812)3.70111705
44regulation of meiosis I (GO:0060631)3.66525026
45behavioral response to nicotine (GO:0035095)3.62735948
46behavioral fear response (GO:0001662)3.61477189
47behavioral defense response (GO:0002209)3.61477189
48prepulse inhibition (GO:0060134)3.59349020
49gamma-aminobutyric acid signaling pathway (GO:0007214)3.56904725
50positive regulation of synaptic transmission, GABAergic (GO:0032230)3.56226128
51G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.54990344
52collecting duct development (GO:0072044)3.54251687
53regulation of glutamate secretion (GO:0014048)3.52444237
54positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.50903692
55regulation of synaptic transmission, glutamatergic (GO:0051966)3.49817632
56synaptic vesicle endocytosis (GO:0048488)3.49359101
57pyrimidine nucleobase catabolic process (GO:0006208)3.48553915
58neuromuscular process controlling balance (GO:0050885)3.48201383
59positive regulation of dendritic spine morphogenesis (GO:0061003)3.47158550
60proline transport (GO:0015824)3.44134898
61regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.43320393
62long-term synaptic potentiation (GO:0060291)3.42785126
63regulation of neurotransmitter secretion (GO:0046928)3.39951484
64regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.39674268
65G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.38470426
66regulation of vesicle fusion (GO:0031338)3.37759251
67fear response (GO:0042596)3.36569862
68neurotransmitter transport (GO:0006836)3.35975451
69positive regulation of dendritic spine development (GO:0060999)3.35643539
70postsynaptic membrane organization (GO:0001941)3.34687680
71cerebral cortex radially oriented cell migration (GO:0021799)3.34673901
72positive regulation of neurotransmitter secretion (GO:0001956)3.34035481
73auditory behavior (GO:0031223)3.31789318
74learning (GO:0007612)3.31540084
75regulation of dendritic spine development (GO:0060998)3.30923689
76presynaptic membrane assembly (GO:0097105)3.27978483
77positive regulation of neurotransmitter transport (GO:0051590)3.27674284
78negative regulation of synaptic transmission, GABAergic (GO:0032229)3.27449133
79regulation of double-strand break repair via homologous recombination (GO:0010569)3.27285336
80dendrite morphogenesis (GO:0048813)3.27072394
81regulation of feeding behavior (GO:0060259)3.26755873
82dendritic spine organization (GO:0097061)3.26472068
83membrane depolarization (GO:0051899)3.26308296
84activation of protein kinase A activity (GO:0034199)3.26277669
85mechanosensory behavior (GO:0007638)3.22958376
86regulation of neurotransmitter transport (GO:0051588)3.22772410
87cell migration in hindbrain (GO:0021535)3.20684084
88cellular potassium ion homeostasis (GO:0030007)3.20448093
89response to histamine (GO:0034776)3.18693297
90presynaptic membrane organization (GO:0097090)3.16312833
91neuronal ion channel clustering (GO:0045161)3.16191344
92negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.16102143
93regulation of neurotransmitter levels (GO:0001505)3.15481917
94negative regulation of amino acid transport (GO:0051956)3.15363551
95response to auditory stimulus (GO:0010996)3.14218053
96central nervous system projection neuron axonogenesis (GO:0021952)3.11756438
97neuromuscular process controlling posture (GO:0050884)3.09739797
98behavioral response to cocaine (GO:0048148)3.09542312
99membrane depolarization during action potential (GO:0086010)3.09392186
100regulation of synaptic transmission (GO:0050804)3.08623916
101innervation (GO:0060384)3.05765473
102establishment of mitochondrion localization (GO:0051654)3.05700027
103adult walking behavior (GO:0007628)3.05419546
104regulation of synapse maturation (GO:0090128)3.02652307
105cerebellar Purkinje cell differentiation (GO:0021702)3.02283443
106synaptic transmission, dopaminergic (GO:0001963)3.02281944
107synapse assembly (GO:0007416)3.00529098
108neuromuscular process (GO:0050905)2.99694801
109mating behavior (GO:0007617)2.99675540
110positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.97991590
111positive regulation of synaptic transmission (GO:0050806)2.97397788
112synaptic transmission (GO:0007268)2.97176844
113regulation of female receptivity (GO:0045924)2.96227943
114cellular anion homeostasis (GO:0030002)2.93871943
115inner ear receptor cell development (GO:0060119)2.92956983
116negative regulation of DNA-dependent DNA replication (GO:2000104)2.91076157
117phosphate ion homeostasis (GO:0055062)2.89953251
118trivalent inorganic anion homeostasis (GO:0072506)2.89953251
119tongue development (GO:0043586)2.89925247
120sodium ion export (GO:0071436)2.83121022
121retina layer formation (GO:0010842)2.81415004
122sympathetic nervous system development (GO:0048485)2.80598755
123positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.76172465
124limb bud formation (GO:0060174)2.66232343
125glycosphingolipid biosynthetic process (GO:0006688)2.62670666
126regulation of dopamine secretion (GO:0014059)2.53860146
127establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.50989074
128mitochondrion transport along microtubule (GO:0047497)2.50989074
129regulation of nuclear cell cycle DNA replication (GO:0033262)2.50799759
130protein polyglutamylation (GO:0018095)2.49584327
131membrane hyperpolarization (GO:0060081)2.46787346
132protein localization to cilium (GO:0061512)2.45172396
133establishment of synaptic vesicle localization (GO:0097480)2.44274265
134synaptic vesicle transport (GO:0048489)2.44274265
135glycerophospholipid catabolic process (GO:0046475)2.42640502
136chaperone-mediated protein transport (GO:0072321)2.42576317
137cerebellar granule cell differentiation (GO:0021707)2.42464246
138positive regulation of synapse assembly (GO:0051965)2.42135559
139renal system development (GO:0072001)2.40667247

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.37337982
2GBX2_23144817_ChIP-Seq_PC3_Human3.57691965
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.48037854
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.24368210
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.23854019
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.17089530
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.82886107
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.82886107
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.82362224
10RARB_27405468_Chip-Seq_BRAIN_Mouse2.78608005
11REST_21632747_ChIP-Seq_MESCs_Mouse2.75161388
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.72288577
13EZH2_27304074_Chip-Seq_ESCs_Mouse2.71048708
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.61004439
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.60680051
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.56879633
17DROSHA_22980978_ChIP-Seq_HELA_Human2.53711658
18* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.51838258
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.46510623
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.37723866
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.36690200
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.29484557
23REST_18959480_ChIP-ChIP_MESCs_Mouse2.26609499
24IKZF1_21737484_ChIP-ChIP_HCT116_Human2.17000754
25MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.99462912
26MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.98101071
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.96501207
28EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.90041753
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.89607306
30AR_21572438_ChIP-Seq_LNCaP_Human1.88550940
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.83490266
32ERG_21242973_ChIP-ChIP_JURKAT_Human1.79519422
33CTBP2_25329375_ChIP-Seq_LNCAP_Human1.77625061
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.72898039
35RBPJ_22232070_ChIP-Seq_NCS_Mouse1.64812527
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.64199182
37FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.60385710
38SMAD4_21799915_ChIP-Seq_A2780_Human1.52342515
39GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.52287897
40PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.51825446
41SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.51467033
42TAF15_26573619_Chip-Seq_HEK293_Human1.51128622
43TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.49964749
44CBX2_27304074_Chip-Seq_ESCs_Mouse1.49948353
45* RING1B_27294783_Chip-Seq_ESCs_Mouse1.45132055
46PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.41682094
47ZFP57_27257070_Chip-Seq_ESCs_Mouse1.41093931
48BMI1_23680149_ChIP-Seq_NPCS_Mouse1.40621039
49GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36565645
50RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.33741707
51RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.31918518
52* RING1B_27294783_Chip-Seq_NPCs_Mouse1.31040652
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.31021048
54GATA1_26923725_Chip-Seq_HPCs_Mouse1.29825461
55ZNF274_21170338_ChIP-Seq_K562_Hela1.29554177
56P300_19829295_ChIP-Seq_ESCs_Human1.29415470
57SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.27601509
58IGF1R_20145208_ChIP-Seq_DFB_Human1.26030937
59POU5F1_16153702_ChIP-ChIP_HESCs_Human1.25559548
60E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.24667535
61SOX2_21211035_ChIP-Seq_LN229_Gbm1.23435717
62TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.22556535
63RNF2_27304074_Chip-Seq_NSC_Mouse1.20722604
64E2F7_22180533_ChIP-Seq_HELA_Human1.19004223
65FLI1_27457419_Chip-Seq_LIVER_Mouse1.18613397
66E2F4_17652178_ChIP-ChIP_JURKAT_Human1.18230604
67AR_19668381_ChIP-Seq_PC3_Human1.17193946
68SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.16186863
69AR_25329375_ChIP-Seq_VCAP_Human1.15611854
70STAT3_23295773_ChIP-Seq_U87_Human1.14127787
71NR3C1_23031785_ChIP-Seq_PC12_Mouse1.13804717
72TOP2B_26459242_ChIP-Seq_MCF-7_Human1.13707827
73* DNAJC2_21179169_ChIP-ChIP_NT2_Human1.13583857
74P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12933908
75WT1_25993318_ChIP-Seq_PODOCYTE_Human1.12690569
76* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12286779
77SOX2_16153702_ChIP-ChIP_HESCs_Human1.10417036
78OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06698145
79KDM2B_26808549_Chip-Seq_K562_Human1.06394250
80EST1_17652178_ChIP-ChIP_JURKAT_Human1.05020526
81WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.04071312
82SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03264684
83NOTCH1_21737748_ChIP-Seq_TLL_Human1.03221893
84ZFP281_18757296_ChIP-ChIP_E14_Mouse1.02789288
85PIAS1_25552417_ChIP-Seq_VCAP_Human1.02535454
86TCF4_23295773_ChIP-Seq_U87_Human1.02469026
87SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.00984533
88TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.00757973
89MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00676213
90* MYC_18940864_ChIP-ChIP_HL60_Human1.00507887
91YY1_21170310_ChIP-Seq_MESCs_Mouse1.00224636
92CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.99523168
93YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99383225
94OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.98551948
95HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.96973097
96AHR_22903824_ChIP-Seq_MCF-7_Human0.96873805
97MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.96866322
98ARNT_22903824_ChIP-Seq_MCF-7_Human0.96652634
99EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.96538538
100CTCF_27219007_Chip-Seq_Bcells_Human0.96152777
101POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.95662021
102TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95662021
103PRDM14_20953172_ChIP-Seq_ESCs_Human0.95067965
104CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.94127660
105CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.93964662
106RUNX2_22187159_ChIP-Seq_PCA_Human0.93862128
107RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.93478709
108VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.91701214
109ZNF217_24962896_ChIP-Seq_MCF-7_Human0.91082817
110IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.90982874
111CBP_20019798_ChIP-Seq_JUKART_Human0.90982874
112POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.90004771
113CDX2_19796622_ChIP-Seq_MESCs_Mouse0.89865084
114VDR_22108803_ChIP-Seq_LS180_Human0.89370010
115NR3C1_21868756_ChIP-Seq_MCF10A_Human0.89343688
116SMAD3_21741376_ChIP-Seq_ESCs_Human0.89302409
117* SMAD3_21741376_ChIP-Seq_HESCs_Human0.88186583
118TP53_20018659_ChIP-ChIP_R1E_Mouse0.87998931
119* ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.87954253
120FUS_26573619_Chip-Seq_HEK293_Human0.87938257
121UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.87663720
122CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87475052
123* SMAD4_21741376_ChIP-Seq_HESCs_Human0.87173686
124TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86549973
125JUN_21703547_ChIP-Seq_K562_Human0.85246023
126EWS_26573619_Chip-Seq_HEK293_Human0.84583548
127TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.84508603
128ZFP281_27345836_Chip-Seq_ESCs_Mouse0.83739637
129PCGF2_27294783_Chip-Seq_NPCs_Mouse0.82712985
130KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.82637233
131PCGF2_27294783_Chip-Seq_ESCs_Mouse0.82553262
132TBX3_20139965_ChIP-Seq_MESCs_Mouse0.80690706

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.45038033
2MP0003880_abnormal_central_pattern5.05646796
3MP0003635_abnormal_synaptic_transmissio4.21190149
4MP0009745_abnormal_behavioral_response3.58033916
5MP0002063_abnormal_learning/memory/cond3.49458133
6MP0004270_analgesia3.48598069
7MP0002822_catalepsy3.38920190
8MP0002064_seizures3.19114281
9MP0002572_abnormal_emotion/affect_behav2.95647768
10MP0001968_abnormal_touch/_nociception2.95067739
11MP0008877_abnormal_DNA_methylation2.88783880
12MP0009046_muscle_twitch2.88196868
13MP0003121_genomic_imprinting2.76660709
14MP0005423_abnormal_somatic_nervous2.74720128
15MP0002272_abnormal_nervous_system2.62389657
16MP0001486_abnormal_startle_reflex2.61493472
17MP0002734_abnormal_mechanical_nocicepti2.44089541
18MP0002736_abnormal_nociception_after2.31523874
19MP0002735_abnormal_chemical_nociception2.31155143
20MP0001501_abnormal_sleep_pattern2.28187190
21MP0001440_abnormal_grooming_behavior2.25413451
22MP0000778_abnormal_nervous_system2.11293956
23MP0002733_abnormal_thermal_nociception2.06668606
24MP0003123_paternal_imprinting2.00945291
25MP0000569_abnormal_digit_pigmentation2.00436285
26MP0001970_abnormal_pain_threshold1.99806595
27MP0002067_abnormal_sensory_capabilities1.95477070
28MP0002184_abnormal_innervation1.82803666
29MP0001529_abnormal_vocalization1.80668711
30MP0002557_abnormal_social/conspecific_i1.78738085
31MP0006276_abnormal_autonomic_nervous1.74384427
32MP0004885_abnormal_endolymph1.74140599
33MP0008569_lethality_at_weaning1.71840867
34MP0003329_amyloid_beta_deposits1.70606577
35MP0004858_abnormal_nervous_system1.70256769
36MP0004924_abnormal_behavior1.68944835
37MP0005386_behavior/neurological_phenoty1.68944835
38MP0004811_abnormal_neuron_physiology1.64533989
39MP0000955_abnormal_spinal_cord1.61470071
40MP0005646_abnormal_pituitary_gland1.59448343
41MP0008789_abnormal_olfactory_epithelium1.51798154
42MP0005645_abnormal_hypothalamus_physiol1.50483611
43MP0002102_abnormal_ear_morphology1.50061862
44MP0002909_abnormal_adrenal_gland1.49482210
45MP0004142_abnormal_muscle_tone1.48312078
46MP0002882_abnormal_neuron_morphology1.47959230
47MP0001984_abnormal_olfaction1.46111455
48MP0002066_abnormal_motor_capabilities/c1.45308854
49MP0009780_abnormal_chondrocyte_physiolo1.43746573
50MP0001905_abnormal_dopamine_level1.43670445
51MP0001502_abnormal_circadian_rhythm1.38821416
52MP0003879_abnormal_hair_cell1.36717405
53MP0003787_abnormal_imprinting1.32659659
54MP0003122_maternal_imprinting1.25265152
55MP0009379_abnormal_foot_pigmentation1.24243239
56MP0003633_abnormal_nervous_system1.23304085
57MP0003693_abnormal_embryo_hatching1.22223145
58MP0002152_abnormal_brain_morphology1.19211783
59MP0008058_abnormal_DNA_repair1.18291953
60MP0001188_hyperpigmentation1.16647814
61MP0001293_anophthalmia1.11368219
62MP0004742_abnormal_vestibular_system1.09075066
63MP0003631_nervous_system_phenotype1.08295273
64MP0000579_abnormal_nail_morphology1.07908940
65MP0000751_myopathy1.04229298
66MP0001346_abnormal_lacrimal_gland1.03210318
67MP0008872_abnormal_physiological_respon1.00044231
68MP0003283_abnormal_digestive_organ0.97632206
69MP0001485_abnormal_pinna_reflex0.97235883
70MP0002069_abnormal_eating/drinking_beha0.93701020
71MP0002229_neurodegeneration0.92342697
72MP0002009_preneoplasia0.91227664
73MP0008874_decreased_physiological_sensi0.88676908
74MP0000015_abnormal_ear_pigmentation0.88235478
75MP0001963_abnormal_hearing_physiology0.87316235
76MP0002752_abnormal_somatic_nervous0.85671338
77MP0005248_abnormal_Harderian_gland0.85647128
78MP0004145_abnormal_muscle_electrophysio0.85244381
79MP0003075_altered_response_to0.85022330
80MP0003634_abnormal_glial_cell0.84978313
81MP0005551_abnormal_eye_electrophysiolog0.84860496
82MP0005310_abnormal_salivary_gland0.84294418
83MP0000631_abnormal_neuroendocrine_gland0.83073571
84MP0001177_atelectasis0.81603532
85MP0000920_abnormal_myelination0.81347301
86MP0009765_abnormal_xenobiotic_induced0.80871634
87MP0003890_abnormal_embryonic-extraembry0.80284466
88MP0010094_abnormal_chromosome_stability0.79159105
89MP0004085_abnormal_heartbeat0.78948790
90MP0003632_abnormal_nervous_system0.78861676
91MP0005171_absent_coat_pigmentation0.78371099
92MP0005394_taste/olfaction_phenotype0.77521719
93MP0005499_abnormal_olfactory_system0.77521719
94MP0003137_abnormal_impulse_conducting0.77279181
95MP0005535_abnormal_body_temperature0.76018774
96MP0003690_abnormal_glial_cell0.75055144
97MP0005409_darkened_coat_color0.75041622
98MP0002653_abnormal_ependyma_morphology0.74933914
99MP0010386_abnormal_urinary_bladder0.73908281
100MP0006292_abnormal_olfactory_placode0.72219760
101MP0008961_abnormal_basal_metabolism0.72015243
102MP0003861_abnormal_nervous_system0.70057453
103MP0006072_abnormal_retinal_apoptosis0.69786415
104MP0004510_myositis0.69286611
105MP0002638_abnormal_pupillary_reflex0.68585796
106MP0001664_abnormal_digestion0.68342278
107MP0004233_abnormal_muscle_weight0.66339467
108MP0000026_abnormal_inner_ear0.65683435
109MP0005195_abnormal_posterior_eye0.65287861
110MP0001986_abnormal_taste_sensitivity0.64697523
111MP0000049_abnormal_middle_ear0.63666154
112MP0000604_amyloidosis0.63298948
113MP0002751_abnormal_autonomic_nervous0.62656721
114MP0003315_abnormal_perineum_morphology0.60928719
115MP0003938_abnormal_ear_development0.60782666
116MP0003698_abnormal_male_reproductive0.60522522
117MP0001943_abnormal_respiration0.59043703
118MP0005253_abnormal_eye_physiology0.58727953
119MP0002837_dystrophic_cardiac_calcinosis0.58332707
120MP0002233_abnormal_nose_morphology0.56123129
121MP0002081_perinatal_lethality0.55811671
122MP0005410_abnormal_fertilization0.55650197
123MP0010769_abnormal_survival0.55607624
124MP0002177_abnormal_outer_ear0.55312777
125MP0009053_abnormal_anal_canal0.54922250
126MP0002090_abnormal_vision0.54383958
127MP0010770_preweaning_lethality0.53649862
128MP0002082_postnatal_lethality0.53649862
129MP0005167_abnormal_blood-brain_barrier0.53558666
130MP0002876_abnormal_thyroid_physiology0.53489326
131MP0010768_mortality/aging0.53035974
132MP0005671_abnormal_response_to0.52278077

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.95415589
2Myokymia (HP:0002411)7.29330439
3Focal seizures (HP:0007359)5.70031822
4Abnormality of the labia minora (HP:0012880)5.65428105
5Visual hallucinations (HP:0002367)5.02985823
6Epileptic encephalopathy (HP:0200134)4.77323577
7Atonic seizures (HP:0010819)4.67716901
8Febrile seizures (HP:0002373)4.35247523
9Progressive cerebellar ataxia (HP:0002073)4.26913440
10Absence seizures (HP:0002121)4.05591094
11Dialeptic seizures (HP:0011146)3.84657388
12Generalized tonic-clonic seizures (HP:0002069)3.73272555
13Broad-based gait (HP:0002136)3.71526097
14Action tremor (HP:0002345)3.53772871
15Hyperventilation (HP:0002883)3.46513205
16Dysdiadochokinesis (HP:0002075)3.36062072
17Supranuclear gaze palsy (HP:0000605)3.34538727
18Amblyopia (HP:0000646)3.33671527
19Gaze-evoked nystagmus (HP:0000640)3.25452193
20Impaired vibration sensation in the lower limbs (HP:0002166)3.20934455
21Dysmetria (HP:0001310)3.20791659
22Poor eye contact (HP:0000817)3.15310055
23Oligodactyly (HP:0012165)3.13687003
24Abnormality of the middle phalanx of the 5th finger (HP:0004219)3.09362616
25Depression (HP:0000716)3.04828283
26Ankle clonus (HP:0011448)3.04413653
27Abnormality of the phalanges of the 5th finger (HP:0004213)3.03075277
28Anxiety (HP:0000739)3.00961755
29Oligodactyly (hands) (HP:0001180)2.98260026
30Truncal ataxia (HP:0002078)2.94538480
31Annular pancreas (HP:0001734)2.90135336
32Scanning speech (HP:0002168)2.81764853
33Genetic anticipation (HP:0003743)2.80036143
34Abnormal eating behavior (HP:0100738)2.79630437
35Abnormal social behavior (HP:0012433)2.79389618
36Impaired social interactions (HP:0000735)2.79389618
37Hemiparesis (HP:0001269)2.73621492
38Cerebral inclusion bodies (HP:0100314)2.71337859
39Stenosis of the external auditory canal (HP:0000402)2.70489071
40Urinary bladder sphincter dysfunction (HP:0002839)2.69782539
41Neurofibrillary tangles (HP:0002185)2.67106337
42Chromsome breakage (HP:0040012)2.65410269
43Drooling (HP:0002307)2.65337127
44Excessive salivation (HP:0003781)2.65337127
45Abnormality of the lower motor neuron (HP:0002366)2.57052173
46Urinary urgency (HP:0000012)2.52085921
47Impaired smooth pursuit (HP:0007772)2.50422200
48Spastic gait (HP:0002064)2.50174689
49Postural instability (HP:0002172)2.46578739
50Stereotypic behavior (HP:0000733)2.43059163
51Limb dystonia (HP:0002451)2.41623228
52Torticollis (HP:0000473)2.41273949
53Epileptiform EEG discharges (HP:0011182)2.41215677
54Pheochromocytoma (HP:0002666)2.39666122
55Split foot (HP:0001839)2.38265545
56Colon cancer (HP:0003003)2.36683697
57Abnormality of binocular vision (HP:0011514)2.36522614
58Diplopia (HP:0000651)2.36522614
59Abnormality of cochlea (HP:0000375)2.34348415
60Chromosomal breakage induced by crosslinking agents (HP:0003221)2.34159044
61Mutism (HP:0002300)2.33782922
62Megalencephaly (HP:0001355)2.33529383
63Symphalangism affecting the phalanges of the hand (HP:0009773)2.29843144
64Fetal akinesia sequence (HP:0001989)2.29162056
65Labial hypoplasia (HP:0000066)2.28788052
66Intention tremor (HP:0002080)2.26890245
67Focal dystonia (HP:0004373)2.26554098
68Absent speech (HP:0001344)2.22580004
69EEG with generalized epileptiform discharges (HP:0011198)2.19869531
70Hypoplastic female external genitalia (HP:0012815)2.19692286
71Progressive inability to walk (HP:0002505)2.19330378
72Bradykinesia (HP:0002067)2.18353707
73Narrow nasal bridge (HP:0000446)2.17642412
74Insidious onset (HP:0003587)2.17273852
75Termporal pattern (HP:0011008)2.17273852
76Supernumerary nipples (HP:0002558)2.14655150
77Birth length less than 3rd percentile (HP:0003561)2.14582490
78Degeneration of the lateral corticospinal tracts (HP:0002314)2.11886822
79Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.11886822
80Status epilepticus (HP:0002133)2.11701852
81Abnormality of ocular smooth pursuit (HP:0000617)2.08998740
82Impaired vibratory sensation (HP:0002495)2.07899190
83Hypsarrhythmia (HP:0002521)2.07630646
84Generalized myoclonic seizures (HP:0002123)2.06048659
85Pointed chin (HP:0000307)2.05720397
86Polyphagia (HP:0002591)2.05298271
87Abnormality of the corticospinal tract (HP:0002492)2.05146119
88Abnormality of the metopic suture (HP:0005556)2.03848257
89Neuroendocrine neoplasm (HP:0100634)2.03430028
90Incomplete penetrance (HP:0003829)2.03036454
91Morphological abnormality of the inner ear (HP:0011390)2.02570117
92Hemiplegia (HP:0002301)2.02320632
93Facial hemangioma (HP:0000329)2.01763474
94Lower limb muscle weakness (HP:0007340)2.00850076
95Craniofacial dystonia (HP:0012179)2.00501561
96Septo-optic dysplasia (HP:0100842)1.99845658
97Papilledema (HP:0001085)1.99601765
98Cortical dysplasia (HP:0002539)1.99220746
99Pendular nystagmus (HP:0012043)1.98698338
100Restlessness (HP:0000711)1.98303611
101Thickened helices (HP:0000391)1.97651468
102Psychosis (HP:0000709)1.97395247
103Insomnia (HP:0100785)1.96022177
104Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.93874189
105Hypoventilation (HP:0002791)1.92954841
106Failure to thrive in infancy (HP:0001531)1.91468205
107Inappropriate behavior (HP:0000719)1.90768934
108Delusions (HP:0000746)1.90419686
109Obstructive sleep apnea (HP:0002870)1.89292267
110Agitation (HP:0000713)1.87800228
111Aqueductal stenosis (HP:0002410)1.86929693
112Specific learning disability (HP:0001328)1.85927819
113Rib fusion (HP:0000902)1.85519833
114Neoplasm of the adrenal cortex (HP:0100641)1.84976079
115Pancreatic cysts (HP:0001737)1.84367566
116Aplasia/Hypoplasia of the sternum (HP:0006714)1.84351165
117Impulsivity (HP:0100710)1.84287858
118Dysmetric saccades (HP:0000641)1.83413725
119Anencephaly (HP:0002323)1.83243894
120Blue irides (HP:0000635)1.82547671
121Gait ataxia (HP:0002066)1.81942336
122Patellar aplasia (HP:0006443)1.81213994
123Lower limb asymmetry (HP:0100559)1.81121284
124Increased circulating renin level (HP:0000848)1.80897161
125Gait imbalance (HP:0002141)1.80714206
126Spastic tetraplegia (HP:0002510)1.79034326
127Protruding tongue (HP:0010808)1.78847093
128Morphological abnormality of the pyramidal tract (HP:0002062)1.76471766
129Abnormal EKG (HP:0003115)1.75873241
130Abnormality of salivation (HP:0100755)1.74915923
131Cerebral hypomyelination (HP:0006808)1.74615112
132Neuronal loss in central nervous system (HP:0002529)1.74505966
133Clumsiness (HP:0002312)1.74225865
134Ventricular fibrillation (HP:0001663)1.73604500
135Abnormality of the labia (HP:0000058)1.73568773
136Inability to walk (HP:0002540)1.73345264
137Back pain (HP:0003418)1.72160646
138Diastasis recti (HP:0001540)1.71514997
139Aplasia of the phalanges of the hand (HP:0009802)1.70754557
140Breast aplasia (HP:0100783)1.70109696
141True hermaphroditism (HP:0010459)1.67561985
142Optic nerve hypoplasia (HP:0000609)1.64918815
143Peripheral hypomyelination (HP:0007182)1.63889470
144Aplasia/Hypoplasia of the patella (HP:0006498)1.62530854
145Hemivertebrae (HP:0002937)1.62106713
146Aplasia/Hypoplasia of the breasts (HP:0010311)1.60586313
147Cystic liver disease (HP:0006706)1.60298726
148Esotropia (HP:0000565)1.60052780
149Iris hypopigmentation (HP:0007730)1.57469996
150Lissencephaly (HP:0001339)1.57077795
151Ectopic kidney (HP:0000086)1.53865544
152Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.53620338

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.42923770
2NTRK35.04824596
3MAP3K93.62089870
4MARK12.72992629
5MAP3K42.60562215
6MINK12.40247723
7TNIK2.37941552
8DAPK22.27913442
9MAP2K72.16145182
10NTRK22.05058048
11PRPF4B2.02608805
12CASK2.00276371
13KSR21.97577545
14ZAK1.90573930
15PAK61.87366370
16WNK31.86367123
17KSR11.83681958
18RIPK41.82536727
19DYRK21.76264654
20PRKD31.69128097
21BRSK11.67414429
22CAMK1D1.64207049
23CDC71.62576538
24DAPK11.58879631
25NTRK11.58243924
26PNCK1.56877863
27ARAF1.56397612
28MAP3K121.54455619
29SIK21.53666314
30CDK51.53065455
31MAP2K41.48106991
32PLK21.47861404
33PKN11.45184238
34MAPK131.41802942
35CAMKK11.36086719
36IRAK21.34473954
37TYRO31.34042957
38FES1.32818060
39MAP3K131.29332662
40UHMK11.28896973
41PLK41.27385635
42MAP4K21.26180466
43GRK51.25196662
44GRK71.18732867
45PINK11.17353133
46EPHB21.17303859
47PRKCG1.15896074
48MKNK21.15794142
49BRSK21.12929592
50CDK191.11986398
51FGR1.10944473
52CAMK2A1.09978803
53STK381.04554994
54CAMK2B1.03969025
55CDK180.95319798
56PHKG10.93007182
57PHKG20.93007182
58CDK150.91870204
59MAP3K20.91689337
60NUAK10.91316798
61MARK20.89954881
62CDK140.87891682
63RAF10.86637734
64CSNK1G20.85426589
65SGK2230.82993336
66SGK4940.82993336
67CAMK10.82459923
68TRIM280.81422508
69TAOK10.81253506
70BMPR20.80524361
71CDK11A0.80496046
72PTK2B0.80169005
73STK110.78501621
74SGK10.75100007
75LATS20.73809603
76OXSR10.72590298
77MARK30.71401597
78NME10.70770905
79WEE10.69813902
80PLK30.67011127
81ICK0.66999839
82WNK40.66696824
83PRKCH0.65345605
84PLK10.65319598
85DYRK1A0.65297259
86TAF10.65015708
87DDR20.64566485
88BCR0.64279145
89CSNK1A10.63966912
90SGK20.62778984
91CDC42BPA0.61644807
92ALK0.59773745
93WNK10.59215027
94CHEK20.59088636
95RET0.58915131
96MAP3K60.58285802
97CAMKK20.57213097
98SIK30.55574060
99RPS6KA40.55035887
100CAMK2D0.54255914
101ATR0.54023634
102BRAF0.53334722
103TNK20.52921602
104PDPK10.51614655
105CSNK1G30.50497393
106CAMK2G0.50209390
107PRKDC0.49791113
108PRKD20.49747385
109PAK30.49425775
110LMTK20.49185637
111PRKCE0.48983245
112PRKCZ0.48937286
113MKNK10.47780414
114SGK30.47112089
115IRAK10.46212617
116TTK0.46130228
117RPS6KA30.45877432
118PDK10.45563372
119BRD40.45184358
120MAP3K10.43024615
121MAP4K10.42872239
122PIM10.42556012
123MAPK100.42392304
124DYRK30.42373548
125FYN0.39894125
126MAP2K10.38932046
127NEK60.37794079
128ROCK20.37700277
129CAMK40.37378900
130MAP3K70.34232190
131DAPK30.33093036
132AKT30.32234304
133STK390.32044960
134TAOK20.31817369
135CAMK1G0.31189967

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.96849619
2Synaptic vesicle cycle_Homo sapiens_hsa047213.05734172
3Olfactory transduction_Homo sapiens_hsa047402.84667669
4Circadian entrainment_Homo sapiens_hsa047132.78896347
5GABAergic synapse_Homo sapiens_hsa047272.78624179
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.77131029
7Long-term potentiation_Homo sapiens_hsa047202.76368495
8Glutamatergic synapse_Homo sapiens_hsa047242.74233045
9Morphine addiction_Homo sapiens_hsa050322.68297127
10Amphetamine addiction_Homo sapiens_hsa050312.67509432
11Mismatch repair_Homo sapiens_hsa034302.44949139
12Dopaminergic synapse_Homo sapiens_hsa047282.27295349
13Salivary secretion_Homo sapiens_hsa049702.15774871
14Homologous recombination_Homo sapiens_hsa034402.04064570
15Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.02211138
16Cocaine addiction_Homo sapiens_hsa050301.94659372
17Cholinergic synapse_Homo sapiens_hsa047251.93432215
18Taste transduction_Homo sapiens_hsa047421.89754189
19Insulin secretion_Homo sapiens_hsa049111.88322038
20Long-term depression_Homo sapiens_hsa047301.82984433
21Gastric acid secretion_Homo sapiens_hsa049711.81084796
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.79922281
23Serotonergic synapse_Homo sapiens_hsa047261.78099964
24Renin secretion_Homo sapiens_hsa049241.75959611
25Calcium signaling pathway_Homo sapiens_hsa040201.71340146
26Allograft rejection_Homo sapiens_hsa053301.70361091
27Oxytocin signaling pathway_Homo sapiens_hsa049211.68074611
28Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.60400875
29DNA replication_Homo sapiens_hsa030301.60045928
30Autoimmune thyroid disease_Homo sapiens_hsa053201.56102891
31Basal transcription factors_Homo sapiens_hsa030221.52866447
32Asthma_Homo sapiens_hsa053101.52070347
33GnRH signaling pathway_Homo sapiens_hsa049121.50618163
34Gap junction_Homo sapiens_hsa045401.44904871
35Collecting duct acid secretion_Homo sapiens_hsa049661.39902708
36Protein export_Homo sapiens_hsa030601.39164587
37Non-homologous end-joining_Homo sapiens_hsa034501.38203369
38Graft-versus-host disease_Homo sapiens_hsa053321.37101691
39Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.33458838
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.30756276
41cAMP signaling pathway_Homo sapiens_hsa040241.30370359
42Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.28739594
43Axon guidance_Homo sapiens_hsa043601.28117171
44Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.23295110
45Estrogen signaling pathway_Homo sapiens_hsa049151.14745014
46Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.12786121
47Melanogenesis_Homo sapiens_hsa049161.12274751
48Glioma_Homo sapiens_hsa052141.08918101
49Vitamin B6 metabolism_Homo sapiens_hsa007501.07505098
50ErbB signaling pathway_Homo sapiens_hsa040121.05237294
51Cardiac muscle contraction_Homo sapiens_hsa042601.05144821
52Intestinal immune network for IgA production_Homo sapiens_hsa046721.04609474
53Phosphatidylinositol signaling system_Homo sapiens_hsa040701.01519731
54Nucleotide excision repair_Homo sapiens_hsa034201.01422136
55Type II diabetes mellitus_Homo sapiens_hsa049301.00192033
56cGMP-PKG signaling pathway_Homo sapiens_hsa040220.97945106
57Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.95310474
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.94268229
59Fanconi anemia pathway_Homo sapiens_hsa034600.92842269
60Dorso-ventral axis formation_Homo sapiens_hsa043200.92688553
61Ether lipid metabolism_Homo sapiens_hsa005650.92655722
62Oocyte meiosis_Homo sapiens_hsa041140.91925756
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.91831690
64Vibrio cholerae infection_Homo sapiens_hsa051100.90851392
65Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.90038316
66Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.88493199
67Phototransduction_Homo sapiens_hsa047440.86976547
68Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.85681330
69Cell cycle_Homo sapiens_hsa041100.80705855
70Choline metabolism in cancer_Homo sapiens_hsa052310.80192579
71Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.77862356
72Tuberculosis_Homo sapiens_hsa051520.77642721
73Pancreatic secretion_Homo sapiens_hsa049720.77386540
74Primary immunodeficiency_Homo sapiens_hsa053400.77003017
75MAPK signaling pathway_Homo sapiens_hsa040100.74647756
76Viral myocarditis_Homo sapiens_hsa054160.74334857
77Phagosome_Homo sapiens_hsa041450.70360882
78Dilated cardiomyopathy_Homo sapiens_hsa054140.70148901
79VEGF signaling pathway_Homo sapiens_hsa043700.69345856
80mRNA surveillance pathway_Homo sapiens_hsa030150.68936452
81Thyroid hormone synthesis_Homo sapiens_hsa049180.68372233
82Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.66963795
83Rheumatoid arthritis_Homo sapiens_hsa053230.66812191
84Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.66571020
85B cell receptor signaling pathway_Homo sapiens_hsa046620.65407856
86Circadian rhythm_Homo sapiens_hsa047100.64072313
87Alzheimers disease_Homo sapiens_hsa050100.63509402
88Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.63473698
89Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62537728
90Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.60470824
91Alcoholism_Homo sapiens_hsa050340.60321728
92Ras signaling pathway_Homo sapiens_hsa040140.60304531
93Wnt signaling pathway_Homo sapiens_hsa043100.59971480
94Rap1 signaling pathway_Homo sapiens_hsa040150.56967083
95Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.56353080
96Epstein-Barr virus infection_Homo sapiens_hsa051690.55990661
97Neurotrophin signaling pathway_Homo sapiens_hsa047220.55950140
98Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54469054
99Proteasome_Homo sapiens_hsa030500.54379119
100RNA polymerase_Homo sapiens_hsa030200.53571558
101Nitrogen metabolism_Homo sapiens_hsa009100.52173884
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.51811792
103Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49244485
104Influenza A_Homo sapiens_hsa051640.48242274
105Basal cell carcinoma_Homo sapiens_hsa052170.47649787
106Glucagon signaling pathway_Homo sapiens_hsa049220.47079455
107Prion diseases_Homo sapiens_hsa050200.47018947
108Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.46955296
109Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45452171
110Leishmaniasis_Homo sapiens_hsa051400.45404195
111Osteoclast differentiation_Homo sapiens_hsa043800.45235611
112Herpes simplex infection_Homo sapiens_hsa051680.44803888
113Oxidative phosphorylation_Homo sapiens_hsa001900.44111999
114mTOR signaling pathway_Homo sapiens_hsa041500.43360028
115Endocytosis_Homo sapiens_hsa041440.42759068
116Non-small cell lung cancer_Homo sapiens_hsa052230.41727050
117Thyroid hormone signaling pathway_Homo sapiens_hsa049190.41488623
118Endometrial cancer_Homo sapiens_hsa052130.39820881
119Parkinsons disease_Homo sapiens_hsa050120.38936063
120Type I diabetes mellitus_Homo sapiens_hsa049400.38821637
121Bile secretion_Homo sapiens_hsa049760.38100814
122Renal cell carcinoma_Homo sapiens_hsa052110.37911509
123Carbohydrate digestion and absorption_Homo sapiens_hsa049730.37375312
124Inositol phosphate metabolism_Homo sapiens_hsa005620.35436188
125Ovarian steroidogenesis_Homo sapiens_hsa049130.35396301
126Longevity regulating pathway - mammal_Homo sapiens_hsa042110.35064200
127Hedgehog signaling pathway_Homo sapiens_hsa043400.34960151
128Fatty acid biosynthesis_Homo sapiens_hsa000610.34607998
129African trypanosomiasis_Homo sapiens_hsa051430.32964734
130Insulin signaling pathway_Homo sapiens_hsa049100.31927834
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.30040508
132Chemokine signaling pathway_Homo sapiens_hsa040620.29172981
133Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.26571707
134Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.25545572
135Regulation of actin cytoskeleton_Homo sapiens_hsa048100.24823066
136Colorectal cancer_Homo sapiens_hsa052100.24646068

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