ASRGL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fusion of sperm to egg plasma membrane (GO:0007342)9.07305310
2sperm motility (GO:0030317)8.55414544
3acrosome reaction (GO:0007340)8.19397198
4axonemal dynein complex assembly (GO:0070286)7.69341517
5acrosome assembly (GO:0001675)7.60910938
6cell wall macromolecule metabolic process (GO:0044036)7.46974015
7cell wall macromolecule catabolic process (GO:0016998)7.46974015
8multicellular organism reproduction (GO:0032504)7.43621406
9epithelial cilium movement (GO:0003351)7.14389946
10plasma membrane fusion (GO:0045026)7.08350179
11sperm-egg recognition (GO:0035036)6.99813826
12motile cilium assembly (GO:0044458)6.71120751
13piRNA metabolic process (GO:0034587)6.43802741
14cilium movement (GO:0003341)6.43072806
15epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.28458956
16cell-cell recognition (GO:0009988)6.27006643
17reproduction (GO:0000003)6.23308628
18binding of sperm to zona pellucida (GO:0007339)6.20075379
19spermatid development (GO:0007286)6.08458418
20negative regulation of inclusion body assembly (GO:0090084)5.66066195
21regulation of cilium movement (GO:0003352)5.55036113
22male meiosis (GO:0007140)5.52306399
23central nervous system myelination (GO:0022010)5.51190440
24axon ensheathment in central nervous system (GO:0032291)5.51190440
25sperm capacitation (GO:0048240)5.34924372
26synaptonemal complex organization (GO:0070193)5.08728270
27single fertilization (GO:0007338)5.06717483
28calcium ion-dependent exocytosis (GO:0017156)4.88593433
29synaptonemal complex assembly (GO:0007130)4.74388057
30regulation of inclusion body assembly (GO:0090083)4.68316978
31behavioral response to nicotine (GO:0035095)4.51359873
32ventricular system development (GO:0021591)4.47533040
33fertilization (GO:0009566)4.31720508
34DNA methylation involved in gamete generation (GO:0043046)4.03807303
35L-amino acid import (GO:0043092)3.99715097
36spermatogenesis (GO:0007283)3.98497992
37postsynaptic membrane organization (GO:0001941)3.97264490
38male gamete generation (GO:0048232)3.96552034
39positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.91721307
40microtubule severing (GO:0051013)3.86121088
41regulation of microtubule-based movement (GO:0060632)3.78020234
42pyrimidine nucleobase catabolic process (GO:0006208)3.73011995
43cell recognition (GO:0008037)3.71007159
44gamete generation (GO:0007276)3.66906533
45male meiosis I (GO:0007141)3.59935581
46protein localization to cilium (GO:0061512)3.56431506
47germ cell development (GO:0007281)3.46245011
48cellular process involved in reproduction in multicellular organism (GO:0022412)3.42510188
49locomotory exploration behavior (GO:0035641)3.32287844
50spermatid nucleus differentiation (GO:0007289)3.26302308
51organic cation transport (GO:0015695)3.25095523
52protein polyglutamylation (GO:0018095)3.22837175
53G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.21979767
54myelination (GO:0042552)3.21079715
55synaptic vesicle maturation (GO:0016188)3.20262020
56DNA double-strand break processing (GO:0000729)3.18839490
57presynaptic membrane assembly (GO:0097105)3.18366343
58amino acid import (GO:0043090)3.18266354
59negative regulation of synaptic transmission, GABAergic (GO:0032229)3.14791844
60ensheathment of neurons (GO:0007272)3.13964985
61axon ensheathment (GO:0008366)3.13964985
62nucleobase catabolic process (GO:0046113)3.10812981
63presynaptic membrane organization (GO:0097090)3.10676885
64left/right pattern formation (GO:0060972)3.10432318
65chromosome organization involved in meiosis (GO:0070192)3.07753066
66gamma-aminobutyric acid transport (GO:0015812)3.07341283
67negative regulation of organelle assembly (GO:1902116)3.06315032
68cellular potassium ion homeostasis (GO:0030007)3.05977955
69neuronal action potential propagation (GO:0019227)3.04632042
70positive regulation of catecholamine secretion (GO:0033605)3.04361631
71C4-dicarboxylate transport (GO:0015740)3.03865550
72indole-containing compound catabolic process (GO:0042436)3.03778152
73indolalkylamine catabolic process (GO:0046218)3.03778152
74tryptophan catabolic process (GO:0006569)3.03778152
75positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.00565348
76regulation of synaptic vesicle transport (GO:1902803)2.98929316
77axoneme assembly (GO:0035082)2.97725105
78neurotransmitter-gated ion channel clustering (GO:0072578)2.96708766
79response to methylmercury (GO:0051597)2.93190887
80microtubule-based movement (GO:0007018)2.92154528
81regulation of oxidative phosphorylation (GO:0002082)2.92079009
82mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.91571528
83mitochondrial respiratory chain complex I assembly (GO:0032981)2.91571528
84NADH dehydrogenase complex assembly (GO:0010257)2.91571528
85microtubule depolymerization (GO:0007019)2.86335947
86regulation of dopamine secretion (GO:0014059)2.85372356
87protein K11-linked deubiquitination (GO:0035871)2.85320526
88protein complex biogenesis (GO:0070271)2.85173434
89positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.84628747
90multicellular organismal reproductive process (GO:0048609)2.84028785
91transmission of nerve impulse (GO:0019226)2.83900344
92regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.83835988
93meiotic nuclear division (GO:0007126)2.83714069
94auditory behavior (GO:0031223)2.82364736
95fatty acid elongation (GO:0030497)2.82361085
96regulation of short-term neuronal synaptic plasticity (GO:0048172)2.82259662
97intraciliary transport (GO:0042073)2.81179766
98neuron cell-cell adhesion (GO:0007158)2.78559167
99ionotropic glutamate receptor signaling pathway (GO:0035235)2.78133717
100potassium ion import (GO:0010107)2.77217562
101regulation of synaptic transmission, dopaminergic (GO:0032225)2.77194240
102indolalkylamine metabolic process (GO:0006586)2.76456290
103mitochondrial respiratory chain complex assembly (GO:0033108)2.75644133
104L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.75409405
105neuronal ion channel clustering (GO:0045161)2.74858212
106glutamate receptor signaling pathway (GO:0007215)2.74689118
107regulation of meiosis I (GO:0060631)2.73605575
108membrane depolarization during action potential (GO:0086010)2.73197766
109mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.72452323
110sodium ion export (GO:0071436)2.72425617
111serotonin metabolic process (GO:0042428)2.72231682
112synapsis (GO:0007129)2.70092492
113meiosis I (GO:0007127)2.69807625
114primary amino compound metabolic process (GO:1901160)2.69619832
115negative regulation of neurotransmitter transport (GO:0051589)2.68488455
116indole-containing compound metabolic process (GO:0042430)2.68135581
117positive regulation of meiosis (GO:0045836)2.66239155
118negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.65814934
119synaptic vesicle exocytosis (GO:0016079)2.64672420
120glutamate secretion (GO:0014047)2.64254830
121regulation of response to osmotic stress (GO:0047484)2.62489580
122tryptophan metabolic process (GO:0006568)2.62290293
123oligodendrocyte differentiation (GO:0048709)2.62251559
124protein localization to synapse (GO:0035418)2.61979197
125positive regulation of meiotic cell cycle (GO:0051446)2.61883289
126neuron-neuron synaptic transmission (GO:0007270)2.60252138
127exploration behavior (GO:0035640)2.58621949
128neuromuscular synaptic transmission (GO:0007274)2.58396647
129cilium morphogenesis (GO:0060271)2.57752177
130chaperone-mediated protein transport (GO:0072321)2.57679904
131regulation of synaptic vesicle exocytosis (GO:2000300)2.57262932
132neurotransmitter uptake (GO:0001504)2.56924724
133meiotic cell cycle (GO:0051321)2.56764932
134seminiferous tubule development (GO:0072520)2.55805651
135ubiquinone biosynthetic process (GO:0006744)2.53638925
136cilium organization (GO:0044782)2.53493652
137synaptic transmission, glutamatergic (GO:0035249)2.53322035
138membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.53095781
139mechanosensory behavior (GO:0007638)2.53067311
140amine catabolic process (GO:0009310)2.52640255
141cellular biogenic amine catabolic process (GO:0042402)2.52640255
142positive regulation of amine transport (GO:0051954)2.52089905
143regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.51666443
144regulation of cellular respiration (GO:0043457)2.51586988
145negative regulation of reactive oxygen species metabolic process (GO:2000378)2.51436206
146dendritic spine morphogenesis (GO:0060997)2.51284597
147response to auditory stimulus (GO:0010996)2.51182892
148establishment of protein localization to mitochondrial membrane (GO:0090151)2.50968239
149vocalization behavior (GO:0071625)2.50725380
150adult walking behavior (GO:0007628)2.49980776
151regulation of neurotransmitter uptake (GO:0051580)2.49535656
152neurotransmitter secretion (GO:0007269)2.49262191
153neuronal action potential (GO:0019228)2.48031447
154fucose catabolic process (GO:0019317)2.47634285
155L-fucose metabolic process (GO:0042354)2.47634285
156L-fucose catabolic process (GO:0042355)2.47634285
157cilium assembly (GO:0042384)2.46711319
158detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.46377803
159cellular component assembly involved in morphogenesis (GO:0010927)2.46205610
160behavioral response to cocaine (GO:0048148)2.44706421
161regulation of synapse structural plasticity (GO:0051823)2.42942469
162ubiquinone metabolic process (GO:0006743)2.41302531
163glycerophospholipid catabolic process (GO:0046475)2.38472219
164glycosphingolipid biosynthetic process (GO:0006688)2.38257080
165water-soluble vitamin biosynthetic process (GO:0042364)2.38027254
166cilium or flagellum-dependent cell motility (GO:0001539)10.4021951

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.33870053
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.75807022
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.43798716
4IGF1R_20145208_ChIP-Seq_DFB_Human3.30361711
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.15319493
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.13369809
7* REST_21632747_ChIP-Seq_MESCs_Mouse2.25960549
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.24761499
9ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.18231379
10GBX2_23144817_ChIP-Seq_PC3_Human2.14891941
11PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.03100873
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.00594422
13HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.93182481
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.87083954
15DROSHA_22980978_ChIP-Seq_HELA_Human1.86169277
16ZNF274_21170338_ChIP-Seq_K562_Hela1.80643777
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.78524281
18KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.77948507
19CBX2_27304074_Chip-Seq_ESCs_Mouse1.75131798
20VDR_22108803_ChIP-Seq_LS180_Human1.71544168
21IRF1_19129219_ChIP-ChIP_H3396_Human1.70839714
22SUZ12_27294783_Chip-Seq_ESCs_Mouse1.67253297
23SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.65682398
24GATA1_26923725_Chip-Seq_HPCs_Mouse1.62322188
25EZH2_27294783_Chip-Seq_ESCs_Mouse1.62203395
26EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.62162882
27MTF2_20144788_ChIP-Seq_MESCs_Mouse1.62138435
28CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.59824314
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.58871244
30GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58135632
31FLI1_27457419_Chip-Seq_LIVER_Mouse1.56847044
32FUS_26573619_Chip-Seq_HEK293_Human1.56396996
33BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.54226795
34RARB_27405468_Chip-Seq_BRAIN_Mouse1.53131389
35* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.52861564
36SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.49420007
37* REST_18959480_ChIP-ChIP_MESCs_Mouse1.48804938
38EWS_26573619_Chip-Seq_HEK293_Human1.48746461
39MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.47110863
40TAF15_26573619_Chip-Seq_HEK293_Human1.42938496
41RNF2_27304074_Chip-Seq_ESCs_Mouse1.42367122
42PCGF2_27294783_Chip-Seq_ESCs_Mouse1.41748962
43JARID2_20064375_ChIP-Seq_MESCs_Mouse1.40342905
44TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36827558
45* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36783482
46NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.35006562
47EST1_17652178_ChIP-ChIP_JURKAT_Human1.34237200
48GABP_17652178_ChIP-ChIP_JURKAT_Human1.34208713
49EZH2_27304074_Chip-Seq_ESCs_Mouse1.32895576
50BMI1_23680149_ChIP-Seq_NPCS_Mouse1.32887737
51SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.32560542
52CTBP1_25329375_ChIP-Seq_LNCAP_Human1.32429339
53TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.31722299
54SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.29250986
55GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.29117382
56SMAD4_21799915_ChIP-Seq_A2780_Human1.29049540
57TAL1_26923725_Chip-Seq_HPCs_Mouse1.29018631
58KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.27984938
59SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.26220449
60TP53_22573176_ChIP-Seq_HFKS_Human1.26128544
61CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.25982852
62KLF5_20875108_ChIP-Seq_MESCs_Mouse1.25265438
63TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.25160135
64EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.25134204
65RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.23016935
66SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.21930354
67NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.21890302
68NANOG_18555785_Chip-Seq_ESCs_Mouse1.21844176
69KDM2B_26808549_Chip-Seq_REH_Human1.21820082
70SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.20438764
71SOX2_19829295_ChIP-Seq_ESCs_Human1.19917439
72NANOG_19829295_ChIP-Seq_ESCs_Human1.19917439
73SMAD3_21741376_ChIP-Seq_EPCs_Human1.19773696
74MYC_18940864_ChIP-ChIP_HL60_Human1.19235008
75ER_23166858_ChIP-Seq_MCF-7_Human1.18376128
76RNF2_18974828_ChIP-Seq_MESCs_Mouse1.18138614
77EZH2_18974828_ChIP-Seq_MESCs_Mouse1.18138614
78* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.17616052
79MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.17433521
80* ERA_21632823_ChIP-Seq_H3396_Human1.17387517
81RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.16795891
82* TCF4_23295773_ChIP-Seq_U87_Human1.16673117
83MYC_19829295_ChIP-Seq_ESCs_Human1.15349846
84SUZ12_27294783_Chip-Seq_NPCs_Mouse1.15090111
85JARID2_20075857_ChIP-Seq_MESCs_Mouse1.14934964
86JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.14042937
87ETS1_20019798_ChIP-Seq_JURKAT_Human1.13937302
88ELK4_26923725_Chip-Seq_MESODERM_Mouse1.13489790
89* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.13022669
90CBP_20019798_ChIP-Seq_JUKART_Human1.12597517
91IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.12597517
92BCAT_22108803_ChIP-Seq_LS180_Human1.10983716
93CMYC_18555785_Chip-Seq_ESCs_Mouse1.10831072
94POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10655636
95TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10655636
96ETV2_25802403_ChIP-Seq_MESCs_Mouse1.10596320
97FLI1_21867929_ChIP-Seq_TH2_Mouse1.10088815
98EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09911183
99* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.09837808
100MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.09670561
101RUNX2_22187159_ChIP-Seq_PCA_Human1.09111214
102NCOR_22424771_ChIP-Seq_293T_Human1.09070957
103TOP2B_26459242_ChIP-Seq_MCF-7_Human1.07354417
104PCGF2_27294783_Chip-Seq_NPCs_Mouse1.06635981
105P300_18555785_Chip-Seq_ESCs_Mouse1.06498425
106P53_22387025_ChIP-Seq_ESCs_Mouse1.06351431
107NFE2_27457419_Chip-Seq_LIVER_Mouse1.05451197
108STAT3_23295773_ChIP-Seq_U87_Human1.04079737
109GATA3_21878914_ChIP-Seq_MCF-7_Human1.03721348
110RNF2_27304074_Chip-Seq_NSC_Mouse1.03206833
111OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01845637
112EED_16625203_ChIP-ChIP_MESCs_Mouse1.01614649
113GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.01094330
114OCT4_20526341_ChIP-Seq_ESCs_Human1.00335445
115IKZF1_21737484_ChIP-ChIP_HCT116_Human1.00243887
116AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99119689
117POU3F2_20337985_ChIP-ChIP_501MEL_Human0.99089434
118PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.99080799
119SMAD4_21741376_ChIP-Seq_EPCs_Human0.98942360
120YY1_21170310_ChIP-Seq_MESCs_Mouse0.98942173
121SUZ12_18555785_Chip-Seq_ESCs_Mouse0.98836033
122UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98070267
123* WDR5_24793694_ChIP-Seq_LNCAP_Human0.97915426
124CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97884500
125SOX9_26525672_Chip-Seq_HEART_Mouse0.97777824
126P300_19829295_ChIP-Seq_ESCs_Human0.97534163
127OCT4_18555785_Chip-Seq_ESCs_Mouse0.97241124
128SMAD3_21741376_ChIP-Seq_ESCs_Human0.97198498
129E2F1_18555785_Chip-Seq_ESCs_Mouse0.97119250
130CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.96829872
131TBL1_22424771_ChIP-Seq_293T_Human0.96500984
132EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.96253167
133TCF4_22108803_ChIP-Seq_LS180_Human0.96220781
134STAT3_18555785_Chip-Seq_ESCs_Mouse0.95503278
135TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95286981
136FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.94431182
137RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.94355717
138KLF4_18555785_Chip-Seq_ESCs_Mouse0.93596316
139* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.93560433
140PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.93518069
141AR_21572438_ChIP-Seq_LNCaP_Human0.93111383
142AR_25329375_ChIP-Seq_VCAP_Human0.92184108
143NR3C1_21868756_ChIP-Seq_MCF10A_Human0.91977139

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization9.07349364
2MP0004859_abnormal_synaptic_plasticity3.86870185
3MP0003698_abnormal_male_reproductive3.49259811
4MP0003880_abnormal_central_pattern3.14839960
5MP0009046_muscle_twitch2.99046233
6MP0001929_abnormal_gametogenesis2.86689056
7MP0004270_analgesia2.83449024
8MP0003635_abnormal_synaptic_transmissio2.66992028
9MP0005423_abnormal_somatic_nervous2.55633686
10MP0000920_abnormal_myelination2.52061108
11MP0008877_abnormal_DNA_methylation2.51926746
12MP0001486_abnormal_startle_reflex2.43446091
13MP0002064_seizures2.36865318
14MP0003329_amyloid_beta_deposits2.35676083
15MP0009745_abnormal_behavioral_response2.34756280
16MP0002272_abnormal_nervous_system2.26311963
17MP0003787_abnormal_imprinting2.21760852
18MP0003690_abnormal_glial_cell2.20920967
19MP0002653_abnormal_ependyma_morphology2.16735157
20MP0002063_abnormal_learning/memory/cond2.04866094
21MP0004885_abnormal_endolymph2.04834369
22MP0002572_abnormal_emotion/affect_behav1.93834466
23MP0006276_abnormal_autonomic_nervous1.88557458
24MP0006292_abnormal_olfactory_placode1.88519666
25MP0008569_lethality_at_weaning1.86918414
26MP0002161_abnormal_fertility/fecundity1.81752580
27MP0002822_catalepsy1.78877073
28MP0002734_abnormal_mechanical_nocicepti1.78688535
29MP0002210_abnormal_sex_determination1.76384112
30MP0001968_abnormal_touch/_nociception1.69249491
31MP0003122_maternal_imprinting1.65911101
32MP0005623_abnormal_meninges_morphology1.65161169
33MP0005551_abnormal_eye_electrophysiolog1.64588637
34MP0005646_abnormal_pituitary_gland1.63446269
35MP0001984_abnormal_olfaction1.63388336
36MP0003634_abnormal_glial_cell1.61848220
37MP0001440_abnormal_grooming_behavior1.55106528
38MP0002102_abnormal_ear_morphology1.54041348
39MP0000778_abnormal_nervous_system1.51223551
40MP0001145_abnormal_male_reproductive1.49175332
41MP0003633_abnormal_nervous_system1.48777185
42MP0005394_taste/olfaction_phenotype1.48017123
43MP0005499_abnormal_olfactory_system1.48017123
44MP0010386_abnormal_urinary_bladder1.47175537
45MP0004142_abnormal_muscle_tone1.47174678
46MP0002067_abnormal_sensory_capabilities1.45893613
47MP0002736_abnormal_nociception_after1.44720579
48MP0001905_abnormal_dopamine_level1.44044298
49MP0004742_abnormal_vestibular_system1.42629218
50MP0003950_abnormal_plasma_membrane1.39725575
51MP0003631_nervous_system_phenotype1.39185938
52MP0001485_abnormal_pinna_reflex1.38334151
53MP0001529_abnormal_vocalization1.37829565
54MP0002229_neurodegeneration1.33710917
55MP0003195_calcinosis1.32692452
56MP0003632_abnormal_nervous_system1.31289140
57MP0003121_genomic_imprinting1.30317188
58MP0000653_abnormal_sex_gland1.29886602
59MP0000955_abnormal_spinal_cord1.29718730
60MP0008872_abnormal_physiological_respon1.29354479
61MP0003136_yellow_coat_color1.26585147
62MP0002882_abnormal_neuron_morphology1.25222054
63MP0003011_delayed_dark_adaptation1.23359644
64MP0004133_heterotaxia1.22420751
65MP0002557_abnormal_social/conspecific_i1.22390302
66MP0001970_abnormal_pain_threshold1.16932488
67MP0002066_abnormal_motor_capabilities/c1.15584892
68MP0003315_abnormal_perineum_morphology1.14402618
69MP0008789_abnormal_olfactory_epithelium1.12825357
70MP0000604_amyloidosis1.12541667
71MP0002733_abnormal_thermal_nociception1.12175389
72MP0005084_abnormal_gallbladder_morpholo1.11869694
73MP0004043_abnormal_pH_regulation1.11221736
74MP0004858_abnormal_nervous_system1.10812774
75MP0004811_abnormal_neuron_physiology1.09430389
76MP0005253_abnormal_eye_physiology1.08686365
77MP0005386_behavior/neurological_phenoty1.08172040
78MP0004924_abnormal_behavior1.08172040
79MP0005389_reproductive_system_phenotype1.05924524
80MP0000566_synostosis1.05725591
81MP0003646_muscle_fatigue1.04832180
82MP0002876_abnormal_thyroid_physiology1.03926381
83MP0001501_abnormal_sleep_pattern1.03841213
84MP0009780_abnormal_chondrocyte_physiolo1.03783186
85MP0004147_increased_porphyrin_level1.03418915
86MP0002152_abnormal_brain_morphology1.03137863
87MP0001502_abnormal_circadian_rhythm1.02663041
88MP0005645_abnormal_hypothalamus_physiol1.02015260
89MP0001963_abnormal_hearing_physiology0.98434489
90MP0008058_abnormal_DNA_repair0.97812661
91MP0005409_darkened_coat_color0.97544750
92MP0000372_irregular_coat_pigmentation0.96951310
93MP0003890_abnormal_embryonic-extraembry0.96108831
94MP0001188_hyperpigmentation0.95857533
95MP0006036_abnormal_mitochondrial_physio0.95451190
96MP0004145_abnormal_muscle_electrophysio0.95003029
97MP0003718_maternal_effect0.94437895
98MP0002837_dystrophic_cardiac_calcinosis0.92866172
99MP0003938_abnormal_ear_development0.92377485
100MP0002735_abnormal_chemical_nociception0.91086399
101MP0004233_abnormal_muscle_weight0.88492938
102MP0006072_abnormal_retinal_apoptosis0.86520761
103MP0002752_abnormal_somatic_nervous0.85152810
104MP0003806_abnormal_nucleotide_metabolis0.84229332
105MP0008875_abnormal_xenobiotic_pharmacok0.83810899
106MP0000751_myopathy0.83362100
107MP0006035_abnormal_mitochondrial_morpho0.80681336
108MP0005171_absent_coat_pigmentation0.79274922
109MP0002909_abnormal_adrenal_gland0.73242161
110MP0002184_abnormal_innervation0.73153570
111MP0003075_altered_response_to0.71267873
112MP0004036_abnormal_muscle_relaxation0.69732926
113MP0004134_abnormal_chest_morphology0.69608200
114MP0005195_abnormal_posterior_eye0.68037585
115MP0005670_abnormal_white_adipose0.67586442
116MP0002638_abnormal_pupillary_reflex0.67395971
117MP0001177_atelectasis0.66279623
118MP0001299_abnormal_eye_distance/0.64798240
119MP0001765_abnormal_ion_homeostasis0.64535060
120MP0002160_abnormal_reproductive_system0.63654596
121MP0000026_abnormal_inner_ear0.60708287
122MP0003879_abnormal_hair_cell0.60283188
123MP0000631_abnormal_neuroendocrine_gland0.57031582
124MP0002090_abnormal_vision0.56487252
125MP0005647_abnormal_sex_gland0.56381791
126MP0003137_abnormal_impulse_conducting0.56335821
127MP0001986_abnormal_taste_sensitivity0.55636161
128MP0005167_abnormal_blood-brain_barrier0.53292261
129MP0003861_abnormal_nervous_system0.52961345
130MP0002069_abnormal_eating/drinking_beha0.51973765

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)7.64068769
2Abnormal respiratory motile cilium morphology (HP:0005938)7.30111643
3Abnormal respiratory epithelium morphology (HP:0012253)7.30111643
4Abnormal ciliary motility (HP:0012262)6.45749394
5Rhinitis (HP:0012384)6.15271537
6Chronic bronchitis (HP:0004469)5.00769714
7Infertility (HP:0000789)4.58167276
8Neurofibrillary tangles (HP:0002185)3.93498338
9Nasal polyposis (HP:0100582)3.92158429
10Nephronophthisis (HP:0000090)3.56455421
11Myokymia (HP:0002411)3.24647053
12Bronchiectasis (HP:0002110)3.22472660
13Abnormality of the nasal mucosa (HP:0000433)3.01872913
14Pancreatic cysts (HP:0001737)2.99647643
15Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.96455570
16Degeneration of the lateral corticospinal tracts (HP:0002314)2.96455570
17Medial flaring of the eyebrow (HP:0010747)2.90660448
18Focal motor seizures (HP:0011153)2.88336688
19Cerebral inclusion bodies (HP:0100314)2.87656098
20Pancreatic fibrosis (HP:0100732)2.86295744
21Acute necrotizing encephalopathy (HP:0006965)2.83455084
22True hermaphroditism (HP:0010459)2.76054283
23Megalencephaly (HP:0001355)2.75700143
24Bronchitis (HP:0012387)2.74012041
25Cerebral hypomyelination (HP:0006808)2.72876066
26Abnormality of the renal medulla (HP:0100957)2.66621172
27Atonic seizures (HP:0010819)2.64748291
28Supranuclear gaze palsy (HP:0000605)2.63470166
29Febrile seizures (HP:0002373)2.62516540
30Progressive cerebellar ataxia (HP:0002073)2.57392465
31Peripheral hypomyelination (HP:0007182)2.56051507
32Gaze-evoked nystagmus (HP:0000640)2.55922439
33Hemiparesis (HP:0001269)2.55735813
34Acute encephalopathy (HP:0006846)2.51465327
35Progressive macrocephaly (HP:0004481)2.49638246
36Hyperglycinemia (HP:0002154)2.48689438
37Abnormal mitochondria in muscle tissue (HP:0008316)2.47034407
38Abnormality of the labia minora (HP:0012880)2.43345771
39Inability to walk (HP:0002540)2.40738525
40Mitochondrial inheritance (HP:0001427)2.40149963
41Congenital stationary night blindness (HP:0007642)2.39707916
42Ankle clonus (HP:0011448)2.38882053
43Abnormality of the corticospinal tract (HP:0002492)2.36624926
44Spastic gait (HP:0002064)2.36335098
45Intention tremor (HP:0002080)2.36200062
46Abnormality of the lower motor neuron (HP:0002366)2.34909238
47Dialeptic seizures (HP:0011146)2.34742831
48Cerebellar dysplasia (HP:0007033)2.34389073
49Epileptic encephalopathy (HP:0200134)2.33355227
50Recurrent otitis media (HP:0000403)2.32335388
51Limb dystonia (HP:0002451)2.30004251
52Increased CSF lactate (HP:0002490)2.29369964
53Polyphagia (HP:0002591)2.28636229
54Retinal dysplasia (HP:0007973)2.27598908
55Dysmetria (HP:0001310)2.24259363
56Male pseudohermaphroditism (HP:0000037)2.24231433
57Tubulointerstitial nephritis (HP:0001970)2.23724234
58Spastic tetraparesis (HP:0001285)2.22807541
59Gait imbalance (HP:0002141)2.21927739
60Aplasia involving bones of the upper limbs (HP:0009823)2.19290096
61Aplasia of the phalanges of the hand (HP:0009802)2.19290096
62Aplasia involving bones of the extremities (HP:0009825)2.19290096
63Action tremor (HP:0002345)2.17888394
64Absence seizures (HP:0002121)2.15303939
65Amyotrophic lateral sclerosis (HP:0007354)2.14940589
66Hyperventilation (HP:0002883)2.14921748
67Recurrent sinusitis (HP:0011108)2.14211759
68CNS hypomyelination (HP:0003429)2.13090649
69Abolished electroretinogram (ERG) (HP:0000550)2.11615680
70Sensory axonal neuropathy (HP:0003390)2.11377389
71Abnormality of saccadic eye movements (HP:0000570)2.10283609
72Male infertility (HP:0003251)2.09384897
73Hypomagnesemia (HP:0002917)2.09356157
74Abnormality of midbrain morphology (HP:0002418)2.09271964
75Molar tooth sign on MRI (HP:0002419)2.09271964
76Lissencephaly (HP:0001339)2.09096497
77Congenital primary aphakia (HP:0007707)2.08388809
78Hyperglycinuria (HP:0003108)2.06329442
79Generalized tonic-clonic seizures (HP:0002069)2.06300837
80Postural instability (HP:0002172)2.05274127
81Focal seizures (HP:0007359)2.04609908
82Cystic liver disease (HP:0006706)2.01499736
83Hepatocellular necrosis (HP:0001404)2.00417854
84Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.4587825
85Dynein arm defect of respiratory motile cilia (HP:0012255)10.4355041
86Absent/shortened dynein arms (HP:0200106)10.4355041
87Dysdiadochokinesis (HP:0002075)1.99697489
88Pendular nystagmus (HP:0012043)1.99637615
89Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.98545005
90Impaired vibration sensation in the lower limbs (HP:0002166)1.98370334
91Decreased central vision (HP:0007663)1.97026493
92Optic nerve hypoplasia (HP:0000609)1.95864624
93Abnormality of the ileum (HP:0001549)1.95627770
94Clumsiness (HP:0002312)1.95586152
95Aplasia/hypoplasia of the uterus (HP:0008684)1.95264649
96Abnormal drinking behavior (HP:0030082)1.95223851
97Polydipsia (HP:0001959)1.95223851
98Lipid accumulation in hepatocytes (HP:0006561)1.94102554
99Broad-based gait (HP:0002136)1.93060763
100Optic disc pallor (HP:0000543)1.92700205
101Absent speech (HP:0001344)1.91806219
102Aplasia/Hypoplasia of the uvula (HP:0010293)1.90327643
103Status epilepticus (HP:0002133)1.90237286
104Hepatic necrosis (HP:0002605)1.89409274
105Meckel diverticulum (HP:0002245)1.89078821
106Retinal atrophy (HP:0001105)1.88818192
107Abnormal rod and cone electroretinograms (HP:0008323)1.87978664
108Hypothermia (HP:0002045)1.86301654
109Sclerocornea (HP:0000647)1.85481104
110Lower limb muscle weakness (HP:0007340)1.85425394
111Polyuria (HP:0000103)1.85009137
112Nephrogenic diabetes insipidus (HP:0009806)1.84631761
113Abnormality of the dental root (HP:0006486)1.83063415
114Taurodontia (HP:0000679)1.83063415
115Abnormality of permanent molar morphology (HP:0011071)1.83063415
116Vaginal atresia (HP:0000148)1.81882430
117Abnormality of glycine metabolism (HP:0010895)1.81238883
118Abnormality of serine family amino acid metabolism (HP:0010894)1.81238883
119Attenuation of retinal blood vessels (HP:0007843)1.80726331
120Chronic hepatic failure (HP:0100626)1.79866406
121Clonus (HP:0002169)1.78949527
122Impaired vibratory sensation (HP:0002495)1.78821944
123Agitation (HP:0000713)1.78630992
124Hypoplasia of the uterus (HP:0000013)1.78307094
125Mutism (HP:0002300)1.78260447
126Abnormal eating behavior (HP:0100738)1.78250120
127Genital tract atresia (HP:0001827)1.77870222
128Gonadotropin excess (HP:0000837)1.77865176
129Supernumerary spleens (HP:0009799)1.75498302
130Urinary urgency (HP:0000012)1.75256256
131Occipital encephalocele (HP:0002085)1.74763122
132Exercise-induced myalgia (HP:0003738)1.74449131
133Abnormality of the dental pulp (HP:0006479)1.74440246
134Truncal ataxia (HP:0002078)1.74112402
135Abnormality of ocular smooth pursuit (HP:0000617)1.73841276
136Abnormality of molar (HP:0011077)1.72843661
137Abnormality of molar morphology (HP:0011070)1.72843661
138Anencephaly (HP:0002323)1.72524140
139Absent rod-and cone-mediated responses on ERG (HP:0007688)1.71554774
140Urinary bladder sphincter dysfunction (HP:0002839)1.71380376
141Intestinal atresia (HP:0011100)1.70755483
142Abnormal biliary tract physiology (HP:0012439)1.69954420
143Bile duct proliferation (HP:0001408)1.69954420
144Epileptiform EEG discharges (HP:0011182)1.69620812
145J-shaped sella turcica (HP:0002680)1.69130439
146Absent thumb (HP:0009777)1.69001752
147Termporal pattern (HP:0011008)1.66654507
148Insidious onset (HP:0003587)1.66654507
149Pachygyria (HP:0001302)1.65896767
150Onion bulb formation (HP:0003383)1.64887111
151Scanning speech (HP:0002168)1.64246358
152Visual hallucinations (HP:0002367)1.62643050
153Bell-shaped thorax (HP:0001591)1.61840770
154Tubulointerstitial abnormality (HP:0001969)1.61066214
155Fibular hypoplasia (HP:0003038)1.60830909
156Postaxial foot polydactyly (HP:0001830)1.60034775
157Postaxial hand polydactyly (HP:0001162)1.58901681
158Decreased motor nerve conduction velocity (HP:0003431)1.58738327
159Progressive inability to walk (HP:0002505)1.57435675
160Type II lissencephaly (HP:0007260)1.57415268
161Aplasia/Hypoplasia of the lens (HP:0008063)1.57176514
162Microglossia (HP:0000171)1.57064954
163Limb ataxia (HP:0002070)1.53726626
164Cholecystitis (HP:0001082)1.53500977
165Abnormal gallbladder physiology (HP:0012438)1.53500977
166Abnormality of binocular vision (HP:0011514)1.51089003
167Diplopia (HP:0000651)1.51089003
168Abnormality of renal excretion (HP:0011036)1.50583274

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK36.19328038
2PDK46.19328038
3STK394.05517819
4PDK23.98546219
5PRKD33.87534226
6FRK3.10762611
7ZAK2.97695177
8ICK2.66329062
9TESK12.58400289
10EPHA42.50074982
11WNK42.39356868
12PNCK2.34044916
13WNK32.31491836
14BMPR1B2.25878348
15LMTK22.19884685
16TLK12.17072404
17MAP4K22.05028709
18DYRK21.93702928
19NTRK21.93661488
20OXSR11.91663861
21ADRBK21.79077198
22TNIK1.78852677
23PTK2B1.70135362
24WNK11.68174792
25TYRO31.59883911
26NTRK31.59097398
27PHKG21.50792645
28PHKG11.50792645
29CSNK1G31.50572782
30INSRR1.48501427
31MARK31.45943585
32PAK61.42366720
33PINK11.42025409
34CDK191.30710481
35STK161.30455103
36GRK11.30158439
37TRIM281.29060446
38MAPKAPK51.29040298
39STK381.28595564
40CSNK1A1L1.27945933
41CSNK1G11.26052131
42NEK61.25420010
43MARK11.21867470
44ACVR1B1.20157761
45MUSK1.12875141
46MAP3K41.10338614
47PDK11.05700429
48VRK11.05064194
49CASK1.03141045
50NTRK11.02786261
51CDC71.02564260
52SGK2231.00010067
53SGK4941.00010067
54PKN10.99457588
55NEK20.95946472
56MAP2K70.95787335
57SRPK10.94945222
58MINK10.94715136
59RPS6KA50.94656828
60PLK40.94624960
61EPHB10.93282922
62MAP3K90.91428398
63CDK50.90463022
64TIE10.90052491
65CAMKK10.89632917
66UHMK10.87426363
67BCKDK0.83963488
68NUAK10.83148685
69PRPF4B0.80516229
70PLK30.79926487
71PRKCG0.76556151
72PDPK10.75550875
73VRK20.72897510
74WEE10.72379842
75FGFR20.70554553
76CDK150.69594755
77TESK20.68818759
78CAMK2A0.68287204
79CAMK1G0.66656788
80PLK10.66488276
81IRAK20.65532027
82CDK180.65146324
83SIK20.63548883
84CDK140.63433045
85CAMK2B0.62648514
86CSNK1A10.62308277
87MAPK130.62151885
88CDK11A0.60844417
89FES0.60529646
90IRAK10.57739545
91ROCK20.57516691
92CCNB10.57332207
93PBK0.57128997
94ADRBK10.57012990
95MARK20.55669530
96DAPK20.55014625
97DYRK30.54108556
98RIPK40.53252324
99PRKCQ0.52725571
100STK110.50191298
101BCR0.50017005
102CAMK2D0.49650947
103MAPK150.49532351
104CAMK2G0.48743797
105ATR0.48508266
106PRKCH0.46818201
107STK38L0.46718239
108AURKA0.45292778
109CSNK1E0.45019824
110CAMK10.42888966
111DAPK30.42450350
112SGK20.42209894
113PRKCI0.40404869
114CHEK20.39638940
115FGR0.39625397
116MAP2K40.38969652
117MAP3K110.37848454
118NME10.37484749
119KSR20.37000045
120CLK10.35272979
121CSNK1G20.34781019
122PRKG10.33716417
123SGK30.31137373
124RPS6KA30.30401207
125PAK30.30166971
126SGK10.28656358
127DYRK1B0.28587143
128FYN0.28580749
129PRKACB0.28382621
130GRK50.27833739
131DYRK1A0.27051188
132PLK20.26934877
133MAPK100.26295543
134PRKACA0.23950181
135CSNK1D0.23817748
136PRKCE0.23803967
137TNK20.23415515
138CAMKK20.22534958
139PRKCZ0.22224326
140MET0.20493038
141CDK30.19593962
142PRKCA0.19437996
143PRKACG0.18513472

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.41706443
2Fatty acid biosynthesis_Homo sapiens_hsa000612.89984109
3Vitamin B6 metabolism_Homo sapiens_hsa007502.67111688
4Nicotine addiction_Homo sapiens_hsa050332.39304412
5Glutamatergic synapse_Homo sapiens_hsa047242.28163870
6Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.20014266
7Amphetamine addiction_Homo sapiens_hsa050312.07262280
8Synaptic vesicle cycle_Homo sapiens_hsa047212.03238730
9Circadian entrainment_Homo sapiens_hsa047132.02320858
10GABAergic synapse_Homo sapiens_hsa047272.01790206
11Morphine addiction_Homo sapiens_hsa050321.90502629
12Propanoate metabolism_Homo sapiens_hsa006401.89113803
13Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.88166980
14Pyruvate metabolism_Homo sapiens_hsa006201.84228119
15Long-term potentiation_Homo sapiens_hsa047201.83407168
16Dorso-ventral axis formation_Homo sapiens_hsa043201.82125605
17Salivary secretion_Homo sapiens_hsa049701.81426625
18Ether lipid metabolism_Homo sapiens_hsa005651.79289340
19Olfactory transduction_Homo sapiens_hsa047401.74174905
20Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.73871465
21Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.70465690
22Gastric acid secretion_Homo sapiens_hsa049711.69132549
23Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.67654200
24Fanconi anemia pathway_Homo sapiens_hsa034601.65539231
25Cardiac muscle contraction_Homo sapiens_hsa042601.60775043
26Fatty acid elongation_Homo sapiens_hsa000621.60334456
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.59975516
28Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.58570428
29RNA polymerase_Homo sapiens_hsa030201.57920878
30Renin secretion_Homo sapiens_hsa049241.56679510
31Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.56470135
32Insulin secretion_Homo sapiens_hsa049111.55118403
33Homologous recombination_Homo sapiens_hsa034401.54570814
34alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.44286255
35Tryptophan metabolism_Homo sapiens_hsa003801.38500986
36Calcium signaling pathway_Homo sapiens_hsa040201.37811810
37Steroid biosynthesis_Homo sapiens_hsa001001.36354043
38Dopaminergic synapse_Homo sapiens_hsa047281.35981881
39Glucagon signaling pathway_Homo sapiens_hsa049221.28566661
40Cocaine addiction_Homo sapiens_hsa050301.27059235
41Regulation of autophagy_Homo sapiens_hsa041401.24505429
42Protein export_Homo sapiens_hsa030601.24101061
43Taste transduction_Homo sapiens_hsa047421.23419382
44beta-Alanine metabolism_Homo sapiens_hsa004101.23052369
45Linoleic acid metabolism_Homo sapiens_hsa005911.22965215
46Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.22504935
47Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.22500060
48Fatty acid metabolism_Homo sapiens_hsa012121.20753087
49Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.20343924
50Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.19636801
51Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.17197418
52Peroxisome_Homo sapiens_hsa041461.17130717
53Carbohydrate digestion and absorption_Homo sapiens_hsa049731.15102822
54Folate biosynthesis_Homo sapiens_hsa007901.14375842
55Maturity onset diabetes of the young_Homo sapiens_hsa049501.14155324
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.09080972
57Glycerophospholipid metabolism_Homo sapiens_hsa005641.06909819
58Cholinergic synapse_Homo sapiens_hsa047251.06763430
59Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.06654454
60Ribosome_Homo sapiens_hsa030101.04897778
61Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.04642650
62cAMP signaling pathway_Homo sapiens_hsa040241.04295104
63Oocyte meiosis_Homo sapiens_hsa041141.03990679
64Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.03880189
65Huntingtons disease_Homo sapiens_hsa050161.01925959
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.01283287
67Phototransduction_Homo sapiens_hsa047441.00935795
68Serotonergic synapse_Homo sapiens_hsa047260.98257555
69Pancreatic secretion_Homo sapiens_hsa049720.97139209
70Aldosterone synthesis and secretion_Homo sapiens_hsa049250.96772576
71Long-term depression_Homo sapiens_hsa047300.96207115
72Oxytocin signaling pathway_Homo sapiens_hsa049210.93959411
73Glycerolipid metabolism_Homo sapiens_hsa005610.93260188
74Collecting duct acid secretion_Homo sapiens_hsa049660.91715813
75Primary bile acid biosynthesis_Homo sapiens_hsa001200.91030470
76Phosphatidylinositol signaling system_Homo sapiens_hsa040700.90088185
77DNA replication_Homo sapiens_hsa030300.89038899
78Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.88348176
79cGMP-PKG signaling pathway_Homo sapiens_hsa040220.85133223
80Purine metabolism_Homo sapiens_hsa002300.84159980
81Axon guidance_Homo sapiens_hsa043600.83971697
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.83593520
83Arginine and proline metabolism_Homo sapiens_hsa003300.82027670
84Base excision repair_Homo sapiens_hsa034100.80654040
85Mismatch repair_Homo sapiens_hsa034300.79764132
86RNA degradation_Homo sapiens_hsa030180.78603572
87Vascular smooth muscle contraction_Homo sapiens_hsa042700.78355076
88Sphingolipid metabolism_Homo sapiens_hsa006000.77929286
89Steroid hormone biosynthesis_Homo sapiens_hsa001400.77253929
90Selenocompound metabolism_Homo sapiens_hsa004500.76986425
91Estrogen signaling pathway_Homo sapiens_hsa049150.76286054
92Mineral absorption_Homo sapiens_hsa049780.75919243
93Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.75788984
94Chemical carcinogenesis_Homo sapiens_hsa052040.75254390
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.74926080
96Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.74037660
97Metabolic pathways_Homo sapiens_hsa011000.73235212
98Sulfur relay system_Homo sapiens_hsa041220.73084801
99Pyrimidine metabolism_Homo sapiens_hsa002400.72044971
100Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.70707396
101Histidine metabolism_Homo sapiens_hsa003400.70648642
102Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.70221423
103Thyroid hormone synthesis_Homo sapiens_hsa049180.69938409
104Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.69417447
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.68966828
106Pentose phosphate pathway_Homo sapiens_hsa000300.68802265
107PPAR signaling pathway_Homo sapiens_hsa033200.68551989
108Butanoate metabolism_Homo sapiens_hsa006500.66679383
109Bile secretion_Homo sapiens_hsa049760.65810231
110Alzheimers disease_Homo sapiens_hsa050100.65491304
111Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.64473323
112Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.63358183
113Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.61109286
114Endocytosis_Homo sapiens_hsa041440.60224997
115Gap junction_Homo sapiens_hsa045400.59468214
116Glutathione metabolism_Homo sapiens_hsa004800.58966954
117Oxidative phosphorylation_Homo sapiens_hsa001900.58133378
118Proteasome_Homo sapiens_hsa030500.56029101
119Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.54847301
120Basal transcription factors_Homo sapiens_hsa030220.54790042
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.51554557
122Fatty acid degradation_Homo sapiens_hsa000710.51112297
123Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.50014073
124Arginine biosynthesis_Homo sapiens_hsa002200.49622787
125Pentose and glucuronate interconversions_Homo sapiens_hsa000400.49503685
126Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.48957624
127Sphingolipid signaling pathway_Homo sapiens_hsa040710.48179916
128Inositol phosphate metabolism_Homo sapiens_hsa005620.47926819
129Alcoholism_Homo sapiens_hsa050340.46306028
130Sulfur metabolism_Homo sapiens_hsa009200.46167178
131Parkinsons disease_Homo sapiens_hsa050120.45402319
132Fat digestion and absorption_Homo sapiens_hsa049750.45251994
133SNARE interactions in vesicular transport_Homo sapiens_hsa041300.44922079
134Carbon metabolism_Homo sapiens_hsa012000.44837029
135Melanogenesis_Homo sapiens_hsa049160.44461332
136Cysteine and methionine metabolism_Homo sapiens_hsa002700.43352275
137Non-homologous end-joining_Homo sapiens_hsa034500.42887887
138Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.42169996
139Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.40947706
140ErbB signaling pathway_Homo sapiens_hsa040120.39419393
141Hedgehog signaling pathway_Homo sapiens_hsa043400.37780499
142Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36474706
143GnRH signaling pathway_Homo sapiens_hsa049120.35529227
144MAPK signaling pathway_Homo sapiens_hsa040100.33139792
145Type II diabetes mellitus_Homo sapiens_hsa049300.32925486

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