| 1 | Birth length less than 3rd percentile (HP:0003561) | 4.16492987 |
| 2 | Chromsome breakage (HP:0040012) | 4.05132127 |
| 3 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.88320365 |
| 4 | Abnormality of chromosome stability (HP:0003220) | 3.43634055 |
| 5 | Abnormality of the preputium (HP:0100587) | 3.28386256 |
| 6 | Multiple enchondromatosis (HP:0005701) | 3.25510269 |
| 7 | Abnormality of the fingertips (HP:0001211) | 3.21587900 |
| 8 | Embryonal renal neoplasm (HP:0011794) | 3.15139160 |
| 9 | Volvulus (HP:0002580) | 3.03436210 |
| 10 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.02193213 |
| 11 | Meckel diverticulum (HP:0002245) | 2.98546940 |
| 12 | Medulloblastoma (HP:0002885) | 2.98267562 |
| 13 | Breast hypoplasia (HP:0003187) | 2.95900073 |
| 14 | Patellar aplasia (HP:0006443) | 2.94036474 |
| 15 | Myelodysplasia (HP:0002863) | 2.92514348 |
| 16 | Abnormality of glycolysis (HP:0004366) | 2.91409047 |
| 17 | Impulsivity (HP:0100710) | 2.88547509 |
| 18 | Ectopic kidney (HP:0000086) | 2.87735276 |
| 19 | Abnormality of methionine metabolism (HP:0010901) | 2.86615737 |
| 20 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.86221385 |
| 21 | Abnormality of the ileum (HP:0001549) | 2.79243530 |
| 22 | Increased serum pyruvate (HP:0003542) | 2.78473961 |
| 23 | Progressive external ophthalmoplegia (HP:0000590) | 2.72166468 |
| 24 | Colon cancer (HP:0003003) | 2.69201866 |
| 25 | Progressive muscle weakness (HP:0003323) | 2.68829719 |
| 26 | Small intestinal stenosis (HP:0012848) | 2.68182569 |
| 27 | Duodenal stenosis (HP:0100867) | 2.68182569 |
| 28 | Sloping forehead (HP:0000340) | 2.67134390 |
| 29 | Microvesicular hepatic steatosis (HP:0001414) | 2.65241595 |
| 30 | Selective tooth agenesis (HP:0001592) | 2.65017319 |
| 31 | Abnormality of the anterior horn cell (HP:0006802) | 2.62340746 |
| 32 | Degeneration of anterior horn cells (HP:0002398) | 2.62340746 |
| 33 | Prominent nose (HP:0000448) | 2.56350540 |
| 34 | Increased hepatocellular lipid droplets (HP:0006565) | 2.51181552 |
| 35 | Reduced antithrombin III activity (HP:0001976) | 2.47755174 |
| 36 | Acute encephalopathy (HP:0006846) | 2.46548559 |
| 37 | Ependymoma (HP:0002888) | 2.45511968 |
| 38 | Oral leukoplakia (HP:0002745) | 2.40567144 |
| 39 | Type I transferrin isoform profile (HP:0003642) | 2.39935971 |
| 40 | Neoplasm of the colon (HP:0100273) | 2.37923462 |
| 41 | T lymphocytopenia (HP:0005403) | 2.37491803 |
| 42 | Bone marrow hypocellularity (HP:0005528) | 2.37412926 |
| 43 | Premature graying of hair (HP:0002216) | 2.29390678 |
| 44 | Increased nuchal translucency (HP:0010880) | 2.29062682 |
| 45 | Rhabdomyosarcoma (HP:0002859) | 2.28622865 |
| 46 | Horseshoe kidney (HP:0000085) | 2.27905755 |
| 47 | Absent thumb (HP:0009777) | 2.27900560 |
| 48 | Abnormality of the duodenum (HP:0002246) | 2.27894729 |
| 49 | Abnormality of the carotid arteries (HP:0005344) | 2.27207660 |
| 50 | Neoplasm of the pancreas (HP:0002894) | 2.25085474 |
| 51 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.23675190 |
| 52 | Abnormal lung lobation (HP:0002101) | 2.22941583 |
| 53 | Abnormality of T cell number (HP:0011839) | 2.21067070 |
| 54 | Acute necrotizing encephalopathy (HP:0006965) | 2.19447059 |
| 55 | Lipid accumulation in hepatocytes (HP:0006561) | 2.19124025 |
| 56 | Sparse lateral eyebrow (HP:0005338) | 2.17913607 |
| 57 | Abnormality of the astrocytes (HP:0100707) | 2.16426581 |
| 58 | Astrocytoma (HP:0009592) | 2.16426581 |
| 59 | Abnormality of serum amino acid levels (HP:0003112) | 2.14440530 |
| 60 | Absent radius (HP:0003974) | 2.14334403 |
| 61 | Rough bone trabeculation (HP:0100670) | 2.14161857 |
| 62 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.13871629 |
| 63 | Abnormality of alanine metabolism (HP:0010916) | 2.12742524 |
| 64 | Hyperalaninemia (HP:0003348) | 2.12742524 |
| 65 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.12742524 |
| 66 | Clubbing of toes (HP:0100760) | 2.12240600 |
| 67 | Pancytopenia (HP:0001876) | 2.11376216 |
| 68 | Cerebral edema (HP:0002181) | 2.10706478 |
| 69 | Reticulocytopenia (HP:0001896) | 2.09575940 |
| 70 | Increased CSF lactate (HP:0002490) | 2.08686618 |
| 71 | Cellular immunodeficiency (HP:0005374) | 2.08272976 |
| 72 | Cafe-au-lait spot (HP:0000957) | 2.08015216 |
| 73 | Anal stenosis (HP:0002025) | 2.06927448 |
| 74 | Increased serum lactate (HP:0002151) | 2.05071277 |
| 75 | Lymphoma (HP:0002665) | 2.05061413 |
| 76 | Acute myeloid leukemia (HP:0004808) | 2.04580364 |
| 77 | Aplastic anemia (HP:0001915) | 2.03498015 |
| 78 | Neoplasm of the oral cavity (HP:0100649) | 2.03463591 |
| 79 | Proximal placement of thumb (HP:0009623) | 2.02698172 |
| 80 | Cleft eyelid (HP:0000625) | 2.02203868 |
| 81 | Long eyelashes (HP:0000527) | 2.02184936 |
| 82 | High pitched voice (HP:0001620) | 2.01785995 |
| 83 | Choanal atresia (HP:0000453) | 2.01229538 |
| 84 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.01087087 |
| 85 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.01087087 |
| 86 | Abnormal protein glycosylation (HP:0012346) | 2.01087087 |
| 87 | Abnormal glycosylation (HP:0012345) | 2.01087087 |
| 88 | Agnosia (HP:0010524) | 1.99938653 |
| 89 | Amaurosis fugax (HP:0100576) | 1.99817560 |
| 90 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.99428344 |
| 91 | Short middle phalanx of the 5th finger (HP:0004220) | 1.98358245 |
| 92 | Microglossia (HP:0000171) | 1.97880205 |
| 93 | Abnormal spermatogenesis (HP:0008669) | 1.96394028 |
| 94 | Supernumerary spleens (HP:0009799) | 1.96117672 |
| 95 | Deviation of the thumb (HP:0009603) | 1.95502621 |
| 96 | Tracheoesophageal fistula (HP:0002575) | 1.95303131 |
| 97 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.93869731 |
| 98 | Basal cell carcinoma (HP:0002671) | 1.93867336 |
| 99 | Optic nerve coloboma (HP:0000588) | 1.93447956 |
| 100 | Atresia of the external auditory canal (HP:0000413) | 1.92041641 |
| 101 | Absent forearm bone (HP:0003953) | 1.91373813 |
| 102 | Aplasia involving forearm bones (HP:0009822) | 1.91373813 |
| 103 | Squamous cell carcinoma (HP:0002860) | 1.91247857 |
| 104 | Short thumb (HP:0009778) | 1.91219528 |
| 105 | Glioma (HP:0009733) | 1.91191033 |
| 106 | Macrocytic anemia (HP:0001972) | 1.89727479 |
| 107 | Abnormality of the labia minora (HP:0012880) | 1.89538120 |
| 108 | IgM deficiency (HP:0002850) | 1.89277509 |
| 109 | Carpal bone hypoplasia (HP:0001498) | 1.85850619 |
| 110 | Facial cleft (HP:0002006) | 1.84198573 |
| 111 | Neoplasm of the adrenal gland (HP:0100631) | 1.83715448 |
| 112 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.82680465 |
| 113 | Orthostatic hypotension (HP:0001278) | 1.82219184 |
| 114 | Abnormality of DNA repair (HP:0003254) | 1.81458936 |
| 115 | Embryonal neoplasm (HP:0002898) | 1.80615871 |
| 116 | Abnormality of T cells (HP:0002843) | 1.79944963 |
| 117 | Sensory axonal neuropathy (HP:0003390) | 1.79475814 |
| 118 | Ovarian neoplasm (HP:0100615) | 1.77785579 |
| 119 | Deep philtrum (HP:0002002) | 1.77389369 |
| 120 | 11 pairs of ribs (HP:0000878) | 1.77228739 |
| 121 | Triphalangeal thumb (HP:0001199) | 1.76896313 |
| 122 | Cortical dysplasia (HP:0002539) | 1.76876674 |
| 123 | Neoplasm of the small intestine (HP:0100833) | 1.76419901 |
| 124 | Abnormality of B cell number (HP:0010975) | 1.76240173 |
| 125 | B lymphocytopenia (HP:0010976) | 1.76240173 |
| 126 | Blepharitis (HP:0000498) | 1.76099570 |
| 127 | Methylmalonic acidemia (HP:0002912) | 1.75838553 |
| 128 | Combined immunodeficiency (HP:0005387) | 1.75237777 |
| 129 | Lip pit (HP:0100267) | 1.75145594 |
| 130 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.74494877 |
| 131 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.73136480 |
| 132 | Abnormality of abdominal situs (HP:0011620) | 1.72000931 |
| 133 | Abdominal situs inversus (HP:0003363) | 1.72000931 |
| 134 | Exercise intolerance (HP:0003546) | 1.71447175 |
| 135 | Progressive macrocephaly (HP:0004481) | 1.70850724 |
| 136 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.70431248 |
| 137 | Absent epiphyses (HP:0010577) | 1.70431248 |
| 138 | Abnormal number of erythroid precursors (HP:0012131) | 1.70291279 |
| 139 | Postnatal microcephaly (HP:0005484) | 1.70279349 |
| 140 | Trismus (HP:0000211) | 1.69277972 |
| 141 | Abnormal number of incisors (HP:0011064) | 1.68795005 |
| 142 | Recurrent viral infections (HP:0004429) | 1.67994933 |
| 143 | Oligodactyly (HP:0012165) | 1.67321536 |
| 144 | Sparse eyelashes (HP:0000653) | 1.66674098 |
| 145 | Cholecystitis (HP:0001082) | 1.66634436 |
| 146 | Abnormal gallbladder physiology (HP:0012438) | 1.66634436 |
| 147 | Hypoplastic labia majora (HP:0000059) | 1.66448490 |
| 148 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.66407157 |
| 149 | Short 4th metacarpal (HP:0010044) | 1.66407157 |
| 150 | Leukopenia (HP:0001882) | 1.66349328 |
| 151 | Overlapping toe (HP:0001845) | 1.65769735 |
| 152 | Cutis marmorata (HP:0000965) | 1.65061177 |
| 153 | Biliary tract neoplasm (HP:0100574) | 1.64329506 |
| 154 | Severe combined immunodeficiency (HP:0004430) | 1.63750742 |
| 155 | Neoplasm of striated muscle (HP:0009728) | 1.63189871 |
ASUN 
