ASXL3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.57843888
2axonal fasciculation (GO:0007413)4.97984287
3neuron recognition (GO:0008038)4.88357621
4pyrimidine nucleobase catabolic process (GO:0006208)4.56514033
5central nervous system projection neuron axonogenesis (GO:0021952)4.37716394
6presynaptic membrane assembly (GO:0097105)4.25837593
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.16288191
8dendritic spine morphogenesis (GO:0060997)4.02670568
9cell migration in hindbrain (GO:0021535)4.00666025
10cerebral cortex radially oriented cell migration (GO:0021799)3.97373920
11negative regulation of axon extension involved in axon guidance (GO:0048843)3.93036307
12presynaptic membrane organization (GO:0097090)3.90220963
13limb bud formation (GO:0060174)3.87405463
14detection of light stimulus involved in visual perception (GO:0050908)3.83409940
15detection of light stimulus involved in sensory perception (GO:0050962)3.83409940
16protein localization to synapse (GO:0035418)3.77698256
17vocalization behavior (GO:0071625)3.77527346
18postsynaptic membrane organization (GO:0001941)3.74725183
19membrane depolarization during action potential (GO:0086010)3.64919689
20negative regulation of axon guidance (GO:1902668)3.62886959
21dendrite morphogenesis (GO:0048813)3.56287717
22gamma-aminobutyric acid transport (GO:0015812)3.55443202
23negative regulation of axon extension (GO:0030517)3.53455506
24regulation of short-term neuronal synaptic plasticity (GO:0048172)3.52469606
25central nervous system neuron axonogenesis (GO:0021955)3.49967851
26layer formation in cerebral cortex (GO:0021819)3.49798120
27behavioral response to nicotine (GO:0035095)3.46381388
28cAMP catabolic process (GO:0006198)3.44442053
29ionotropic glutamate receptor signaling pathway (GO:0035235)3.44365500
30protein polyglutamylation (GO:0018095)3.43597127
31head development (GO:0060322)3.42629553
32regulation of glutamate receptor signaling pathway (GO:1900449)3.40401001
33positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.40110859
34nucleobase catabolic process (GO:0046113)3.33686320
35exploration behavior (GO:0035640)3.33233974
36negative regulation of cytosolic calcium ion concentration (GO:0051481)3.31939753
37establishment of mitochondrion localization (GO:0051654)3.30973551
38cyclic nucleotide catabolic process (GO:0009214)3.30831567
39regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.27436826
40regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.26191375
41positive regulation of synapse assembly (GO:0051965)3.26178878
42regulation of axon extension involved in axon guidance (GO:0048841)3.20946734
43glutamate receptor signaling pathway (GO:0007215)3.11916897
44synaptic transmission, glutamatergic (GO:0035249)3.10848021
45axon extension (GO:0048675)3.10775945
46dendrite development (GO:0016358)3.10381282
47regulation of axon guidance (GO:1902667)3.09919458
48calcium ion import (GO:0070509)3.08028692
49establishment of protein localization to Golgi (GO:0072600)3.07924390
50central nervous system myelination (GO:0022010)3.06807581
51axon ensheathment in central nervous system (GO:0032291)3.06807581
52neuronal action potential (GO:0019228)3.04083084
53transmission of nerve impulse (GO:0019226)3.01885969
54locomotory exploration behavior (GO:0035641)3.01440640
55negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.99872554
56metanephric mesenchyme development (GO:0072075)2.99036444
57negative regulation of axonogenesis (GO:0050771)2.98830322
58regulation of synapse assembly (GO:0051963)2.96977966
59lateral sprouting from an epithelium (GO:0060601)2.96905235
60long-chain fatty acid biosynthetic process (GO:0042759)2.96085625
61regulation of cilium movement (GO:0003352)2.94778363
62mechanosensory behavior (GO:0007638)2.94241315
63regulation of respiratory system process (GO:0044065)2.93609595
64neuron-neuron synaptic transmission (GO:0007270)2.93208878
65synaptic vesicle exocytosis (GO:0016079)2.92123856
66cranial nerve morphogenesis (GO:0021602)2.92093559
67neurotransmitter-gated ion channel clustering (GO:0072578)2.91745419
68short-term memory (GO:0007614)2.91614623
69positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.89619183
70hippocampus development (GO:0021766)2.88358113
71protein targeting to Golgi (GO:0000042)2.88194604
72synapse assembly (GO:0007416)2.87325928
73kidney mesenchyme development (GO:0072074)2.87189848
74response to auditory stimulus (GO:0010996)2.86169605
75apical protein localization (GO:0045176)2.84888237
76startle response (GO:0001964)2.83210794
77protein localization to cilium (GO:0061512)2.82985923
78regulation of dendritic spine morphogenesis (GO:0061001)2.82303670
79membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.80471607
80cerebellum development (GO:0021549)2.80395983
81regulation of action potential (GO:0098900)2.79774648
82regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.76755178
83response to pheromone (GO:0019236)2.76515694
84behavioral response to ethanol (GO:0048149)2.74867563
85proline transport (GO:0015824)2.74663416
86positive regulation of dendritic spine morphogenesis (GO:0061003)2.74180870
87regulation of protein kinase A signaling (GO:0010738)2.72573248
88mitochondrion transport along microtubule (GO:0047497)2.72420980
89establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.72420980
90regulation of synapse structural plasticity (GO:0051823)2.69138021
91neuronal action potential propagation (GO:0019227)2.68447934
92negative regulation of microtubule polymerization (GO:0031115)2.65824255
93epithelial cilium movement (GO:0003351)2.65377246
94neuron migration (GO:0001764)2.65214150
95neural tube formation (GO:0001841)2.64625660
96negative regulation of neurotransmitter transport (GO:0051589)2.64308629
97glycosphingolipid biosynthetic process (GO:0006688)2.63907874
98retrograde transport, vesicle recycling within Golgi (GO:0000301)2.63689327
99axonogenesis (GO:0007409)2.62349501
100dendritic spine organization (GO:0097061)2.61105665
101regulation of synapse organization (GO:0050807)2.60880637
102neuronal ion channel clustering (GO:0045161)2.60770848
103nonmotile primary cilium assembly (GO:0035058)2.59860118
104synapse organization (GO:0050808)2.59378951
105epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.59082405
106regulation of respiratory gaseous exchange (GO:0043576)2.58560289
107protein localization to Golgi apparatus (GO:0034067)2.58467456
108brain morphogenesis (GO:0048854)2.57801879
109calcium ion-dependent exocytosis (GO:0017156)2.57452293
110negative regulation of dendrite development (GO:2000171)2.56574178
111cerebellar granule cell differentiation (GO:0021707)2.56556798
112neuron projection extension (GO:1990138)2.56086884
113synaptic vesicle maturation (GO:0016188)2.55780475
114regulation of synaptic transmission, glutamatergic (GO:0051966)2.54932092
115retinal ganglion cell axon guidance (GO:0031290)2.54378123
116reflex (GO:0060004)2.53509307
117regulation of synaptic vesicle exocytosis (GO:2000300)2.53389076
118auditory behavior (GO:0031223)2.52787362
119inositol phosphate catabolic process (GO:0071545)2.52665655
120homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.52365412
121regulation of dendritic spine development (GO:0060998)2.51541563
122negative regulation of synaptic transmission, GABAergic (GO:0032229)2.51327958
123retinal cone cell development (GO:0046549)2.50892384
124adult walking behavior (GO:0007628)2.50269309
125membrane depolarization (GO:0051899)2.49645233
126positive regulation of synapse maturation (GO:0090129)2.49408249
127cerebellar Purkinje cell differentiation (GO:0021702)2.49259547
128synaptic vesicle endocytosis (GO:0048488)2.49085173
129G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.48661781
130regulation of collateral sprouting (GO:0048670)2.48443402
131cilium organization (GO:0044782)2.47494481
132regulation of long-term neuronal synaptic plasticity (GO:0048169)2.47370682
133cilium assembly (GO:0042384)2.47024899
134regulation of microtubule-based movement (GO:0060632)2.46738204
135regulation of neuronal synaptic plasticity (GO:0048168)2.46549733
136establishment of nucleus localization (GO:0040023)2.46192507
137sympathetic nervous system development (GO:0048485)2.45308532
138neuron remodeling (GO:0016322)2.45298618
139positive regulation of dendritic spine development (GO:0060999)2.45113911
140spinal cord motor neuron differentiation (GO:0021522)2.45087494
141cochlea development (GO:0090102)2.44641749
142regulation of feeding behavior (GO:0060259)2.44524442
143ephrin receptor signaling pathway (GO:0048013)2.44365609
144regulation of excitatory postsynaptic membrane potential (GO:0060079)2.44025853
145gamma-aminobutyric acid signaling pathway (GO:0007214)2.43832326
146calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.43652346
147regulation of extent of cell growth (GO:0061387)2.43108971
148intraciliary transport (GO:0042073)2.43049447
149membrane hyperpolarization (GO:0060081)2.43021122
150kidney morphogenesis (GO:0060993)2.42382522
151atrial cardiac muscle cell action potential (GO:0086014)2.42258603
152neuron projection morphogenesis (GO:0048812)2.42233626
153tachykinin receptor signaling pathway (GO:0007217)2.41940378

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.54386358
2GBX2_23144817_ChIP-Seq_PC3_Human3.73073272
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.02062508
4EZH2_27304074_Chip-Seq_ESCs_Mouse2.95926117
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.79811258
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.68445406
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.62192009
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.59452512
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.54946878
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.54946878
11EED_16625203_ChIP-ChIP_MESCs_Mouse2.53325587
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.46033401
13CBX2_27304074_Chip-Seq_ESCs_Mouse2.46027464
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.41644314
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.32436640
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.28392128
17* BMI1_23680149_ChIP-Seq_NPCS_Mouse2.24709393
18TAF15_26573619_Chip-Seq_HEK293_Human2.16734127
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.15486913
20ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.15360675
21ZFP57_27257070_Chip-Seq_ESCs_Mouse2.12113755
22CTBP2_25329375_ChIP-Seq_LNCAP_Human2.08644408
23PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.08169223
24* EZH2_27294783_Chip-Seq_ESCs_Mouse2.07955057
25SUZ12_27294783_Chip-Seq_ESCs_Mouse1.99791440
26MTF2_20144788_ChIP-Seq_MESCs_Mouse1.96179615
27PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.96016738
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.95037161
29RBPJ_22232070_ChIP-Seq_NCS_Mouse1.92536329
30RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.90453203
31CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.89641141
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.87143068
33AR_21572438_ChIP-Seq_LNCaP_Human1.86162272
34SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.85956531
35RNF2_27304074_Chip-Seq_NSC_Mouse1.85635863
36* FUS_26573619_Chip-Seq_HEK293_Human1.84910942
37* REST_21632747_ChIP-Seq_MESCs_Mouse1.77861745
38POU3F2_20337985_ChIP-ChIP_501MEL_Human1.74788630
39P300_19829295_ChIP-Seq_ESCs_Human1.74078228
40SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.73018490
41IGF1R_20145208_ChIP-Seq_DFB_Human1.69329247
42FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.68326040
43* SMAD3_21741376_ChIP-Seq_EPCs_Human1.58109987
44SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.56697176
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.56410588
46TOP2B_26459242_ChIP-Seq_MCF-7_Human1.56013277
47DROSHA_22980978_ChIP-Seq_HELA_Human1.55756107
48* SMAD4_21799915_ChIP-Seq_A2780_Human1.52946965
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.52664409
50POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.46360373
51TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46360373
52CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.46135110
53PIAS1_25552417_ChIP-Seq_VCAP_Human1.45266299
54* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.44359867
55* RING1B_27294783_Chip-Seq_NPCs_Mouse1.44036679
56EWS_26573619_Chip-Seq_HEK293_Human1.37636559
57RING1B_27294783_Chip-Seq_ESCs_Mouse1.37235706
58FLI1_27457419_Chip-Seq_LIVER_Mouse1.37171043
59CBP_20019798_ChIP-Seq_JUKART_Human1.35988657
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.35988657
61ER_23166858_ChIP-Seq_MCF-7_Human1.30686549
62POU5F1_16153702_ChIP-ChIP_HESCs_Human1.29431472
63* BCAT_22108803_ChIP-Seq_LS180_Human1.29027645
64BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.28359751
65REST_18959480_ChIP-ChIP_MESCs_Mouse1.27570811
66VDR_22108803_ChIP-Seq_LS180_Human1.26823878
67AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.25566025
68STAT3_23295773_ChIP-Seq_U87_Human1.25134310
69* ZNF274_21170338_ChIP-Seq_K562_Hela1.22585532
70ARNT_22903824_ChIP-Seq_MCF-7_Human1.21275555
71CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20634845
72TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.19961395
73PCGF2_27294783_Chip-Seq_ESCs_Mouse1.18731696
74MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18662003
75* CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18233066
76AHR_22903824_ChIP-Seq_MCF-7_Human1.18216149
77WT1_19549856_ChIP-ChIP_CCG9911_Human1.17986056
78TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17520895
79SMAD_19615063_ChIP-ChIP_OVARY_Human1.16851286
80SOX2_21211035_ChIP-Seq_LN229_Gbm1.16558787
81TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.14526793
82NANOG_18555785_Chip-Seq_ESCs_Mouse1.14248649
83FLI1_21867929_ChIP-Seq_TH2_Mouse1.13974355
84TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13743111
85NR3C1_21868756_ChIP-Seq_MCF10A_Human1.13186532
86RARB_27405468_Chip-Seq_BRAIN_Mouse1.12715497
87* RUNX2_22187159_ChIP-Seq_PCA_Human1.12658670
88KDM2B_26808549_Chip-Seq_REH_Human1.12545401
89YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11070364
90GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10916709
91TCF4_23295773_ChIP-Seq_U87_Human1.10592489
92* TAL1_26923725_Chip-Seq_HPCs_Mouse1.09837007
93AR_25329375_ChIP-Seq_VCAP_Human1.09766382
94P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09535201
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.09504836
96SOX9_26525672_Chip-Seq_HEART_Mouse1.08651805
97TP53_18474530_ChIP-ChIP_U2OS_Human1.08335615
98ZNF217_24962896_ChIP-Seq_MCF-7_Human1.08251148
99* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.05553899
100TP53_22573176_ChIP-Seq_HFKS_Human1.05094323
101P53_22387025_ChIP-Seq_ESCs_Mouse1.05093413
102HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.04917861
103JUN_21703547_ChIP-Seq_K562_Human1.04402858
104MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02996360
105KLF5_20875108_ChIP-Seq_MESCs_Mouse1.02858829
106* TCF4_22108803_ChIP-Seq_LS180_Human1.02241237
107PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00876968
108AR_19668381_ChIP-Seq_PC3_Human1.00874326
109SMAD4_21741376_ChIP-Seq_EPCs_Human1.00811442
110TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.00701234
111* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.00577785
112EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.99580324
113E2F1_18555785_Chip-Seq_ESCs_Mouse0.98592601
114PRDM14_20953172_ChIP-Seq_ESCs_Human0.96772834
115LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95860935
116KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.95154407
117MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94779090
118STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.94463872

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.35007736
2MP0004859_abnormal_synaptic_plasticity3.07937546
3MP0000778_abnormal_nervous_system3.07061385
4MP0004270_analgesia2.83907194
5MP0002822_catalepsy2.72559299
6MP0005423_abnormal_somatic_nervous2.61957136
7MP0003635_abnormal_synaptic_transmissio2.44016786
8MP0003122_maternal_imprinting2.36885986
9MP0003787_abnormal_imprinting2.34139278
10MP0006276_abnormal_autonomic_nervous2.30633048
11MP0006292_abnormal_olfactory_placode2.14163720
12MP0002184_abnormal_innervation2.13290495
13MP0001486_abnormal_startle_reflex2.12127248
14MP0002063_abnormal_learning/memory/cond2.11233445
15MP0002734_abnormal_mechanical_nocicepti2.00308100
16MP0003121_genomic_imprinting1.94538657
17MP0005551_abnormal_eye_electrophysiolog1.92751170
18MP0008789_abnormal_olfactory_epithelium1.91175011
19MP0000569_abnormal_digit_pigmentation1.90456480
20MP0003385_abnormal_body_wall1.89802730
21MP0002572_abnormal_emotion/affect_behav1.86782995
22MP0000566_synostosis1.85130852
23MP0009745_abnormal_behavioral_response1.82967747
24MP0002638_abnormal_pupillary_reflex1.80146365
25MP0002064_seizures1.75313089
26MP0002735_abnormal_chemical_nociception1.72381355
27MP0002938_white_spotting1.72359103
28MP0002837_dystrophic_cardiac_calcinosis1.72036320
29MP0001968_abnormal_touch/_nociception1.71785128
30MP0005499_abnormal_olfactory_system1.70989704
31MP0005394_taste/olfaction_phenotype1.70989704
32MP0002272_abnormal_nervous_system1.70394087
33MP0004742_abnormal_vestibular_system1.68236555
34MP0002909_abnormal_adrenal_gland1.64714361
35MP0009046_muscle_twitch1.62631261
36MP0000955_abnormal_spinal_cord1.61889783
37MP0001188_hyperpigmentation1.61358779
38MP0003938_abnormal_ear_development1.60252755
39MP0001529_abnormal_vocalization1.56646455
40MP0009250_abnormal_appendicular_skeleto1.56112892
41MP0002557_abnormal_social/conspecific_i1.55175750
42MP0002102_abnormal_ear_morphology1.54429482
43MP0002067_abnormal_sensory_capabilities1.49095740
44MP0000049_abnormal_middle_ear1.48824173
45MP0002882_abnormal_neuron_morphology1.48419637
46MP0000537_abnormal_urethra_morphology1.44045630
47MP0003937_abnormal_limbs/digits/tail_de1.42650093
48MP0003755_abnormal_palate_morphology1.41529409
49MP0000631_abnormal_neuroendocrine_gland1.41348972
50MP0005645_abnormal_hypothalamus_physiol1.39519613
51MP0003861_abnormal_nervous_system1.39051111
52MP0005171_absent_coat_pigmentation1.38734342
53MP0001485_abnormal_pinna_reflex1.37975592
54MP0001984_abnormal_olfaction1.33524413
55MP0004885_abnormal_endolymph1.32597635
56MP0005409_darkened_coat_color1.32460892
57MP0002152_abnormal_brain_morphology1.31996434
58MP0002234_abnormal_pharynx_morphology1.30055663
59MP0001440_abnormal_grooming_behavior1.29736886
60MP0002233_abnormal_nose_morphology1.29502493
61MP0004811_abnormal_neuron_physiology1.28979112
62MP0000026_abnormal_inner_ear1.28969667
63MP0003942_abnormal_urinary_system1.28846936
64MP0010030_abnormal_orbit_morphology1.28414459
65MP0001501_abnormal_sleep_pattern1.27921416
66MP0005253_abnormal_eye_physiology1.27556930
67MP0006072_abnormal_retinal_apoptosis1.25303044
68MP0002733_abnormal_thermal_nociception1.24524765
69MP0002752_abnormal_somatic_nervous1.23212380
70MP0005386_behavior/neurological_phenoty1.21958673
71MP0004924_abnormal_behavior1.21958673
72MP0000534_abnormal_ureter_morphology1.21566773
73MP0005248_abnormal_Harderian_gland1.20242508
74MP0002736_abnormal_nociception_after1.18655809
75MP0001970_abnormal_pain_threshold1.16973328
76MP0001905_abnormal_dopamine_level1.15339524
77MP0003195_calcinosis1.13582528
78MP0003123_paternal_imprinting1.12076870
79MP0003890_abnormal_embryonic-extraembry1.10978203
80MP0004145_abnormal_muscle_electrophysio1.10754496
81MP0002751_abnormal_autonomic_nervous1.09827006
82MP0002249_abnormal_larynx_morphology1.09540287
83MP0003315_abnormal_perineum_morphology1.08117103
84MP0002653_abnormal_ependyma_morphology1.07063593
85MP0001963_abnormal_hearing_physiology1.06603750
86MP0002066_abnormal_motor_capabilities/c1.06271479
87MP0002116_abnormal_craniofacial_bone1.04725228
88MP0003283_abnormal_digestive_organ1.04480592
89MP0001346_abnormal_lacrimal_gland1.02809700
90MP0009053_abnormal_anal_canal1.01690949
91MP0005187_abnormal_penis_morphology1.01141543
92MP0000920_abnormal_myelination1.00548867
93MP0003935_abnormal_craniofacial_develop0.97961605
94MP0001299_abnormal_eye_distance/0.97235933
95MP0005646_abnormal_pituitary_gland0.96058406
96MP0002081_perinatal_lethality0.93137309
97MP0004142_abnormal_muscle_tone0.92896221
98MP0004133_heterotaxia0.92112030
99MP0002876_abnormal_thyroid_physiology0.91898334
100MP0002229_neurodegeneration0.91854830
101MP0001293_anophthalmia0.91463146
102MP0003119_abnormal_digestive_system0.90980588
103MP0003633_abnormal_nervous_system0.90787607
104MP0005367_renal/urinary_system_phenotyp0.90476358
105MP0000516_abnormal_urinary_system0.90476358
106MP0002069_abnormal_eating/drinking_beha0.90298180
107MP0005623_abnormal_meninges_morphology0.90159624
108MP0004215_abnormal_myocardial_fiber0.89832761
109MP0005195_abnormal_posterior_eye0.89496023
110MP0001502_abnormal_circadian_rhythm0.88497525
111MP0008877_abnormal_DNA_methylation0.86736113
112MP0002177_abnormal_outer_ear0.85949815
113MP0000762_abnormal_tongue_morphology0.85881577
114MP0004134_abnormal_chest_morphology0.85806177
115MP0004043_abnormal_pH_regulation0.85535260
116MP0003698_abnormal_male_reproductive0.84765679
117MP0002932_abnormal_joint_morphology0.84333319
118MP0001286_abnormal_eye_development0.84077501
119MP0004858_abnormal_nervous_system0.83999816
120MP0003631_nervous_system_phenotype0.83280342
121MP0000462_abnormal_digestive_system0.82888191
122MP0004085_abnormal_heartbeat0.82774290
123MP0010386_abnormal_urinary_bladder0.82524593
124MP0001944_abnormal_pancreas_morphology0.81965700
125MP0000427_abnormal_hair_cycle0.81327511
126MP0003632_abnormal_nervous_system0.79689719
127MP0001177_atelectasis0.79053198
128MP0003941_abnormal_skin_development0.78748859
129MP0005379_endocrine/exocrine_gland_phen0.77223650
130MP0002928_abnormal_bile_duct0.75634090
131MP0008872_abnormal_physiological_respon0.73849868
132MP0008569_lethality_at_weaning0.72986140

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)4.14507568
2Intestinal atresia (HP:0011100)3.63060899
3Focal motor seizures (HP:0011153)3.62911229
4Aplasia/Hypoplasia of the fovea (HP:0008060)3.19231559
5Hypoplasia of the fovea (HP:0007750)3.19231559
6Pancreatic fibrosis (HP:0100732)3.14419644
7Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.08209817
8Short 4th metacarpal (HP:0010044)3.08209817
9Molar tooth sign on MRI (HP:0002419)3.06104654
10Abnormality of midbrain morphology (HP:0002418)3.06104654
11Insidious onset (HP:0003587)3.03144762
12Termporal pattern (HP:0011008)3.03144762
13Abnormality of macular pigmentation (HP:0008002)3.00541021
14Abnormality of the corticospinal tract (HP:0002492)3.00164119
15Cutaneous finger syndactyly (HP:0010554)2.98360572
16Broad-based gait (HP:0002136)2.94423741
17Degeneration of the lateral corticospinal tracts (HP:0002314)2.93490427
18Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.93490427
19Focal seizures (HP:0007359)2.90703321
20Severe visual impairment (HP:0001141)2.88580418
21True hermaphroditism (HP:0010459)2.86103988
22Abnormal rod and cone electroretinograms (HP:0008323)2.84599158
23Midline defect of the nose (HP:0004122)2.81925443
24Renal cortical cysts (HP:0000803)2.81529691
25Epileptic encephalopathy (HP:0200134)2.80209836
26Pancreatic cysts (HP:0001737)2.78402797
27Atonic seizures (HP:0010819)2.77806051
28Abnormality of the renal cortex (HP:0011035)2.77741809
29Hepatoblastoma (HP:0002884)2.75720280
30Abnormality of the renal medulla (HP:0100957)2.73549616
31Febrile seizures (HP:0002373)2.73070746
32Hyperventilation (HP:0002883)2.72913719
33Abnormality of the fovea (HP:0000493)2.69152028
34Inability to walk (HP:0002540)2.66990255
35Agitation (HP:0000713)2.61707522
36Chronic hepatic failure (HP:0100626)2.58905248
37Drooling (HP:0002307)2.55780936
38Excessive salivation (HP:0003781)2.55780936
39Cutaneous syndactyly (HP:0012725)2.52702385
40Hypsarrhythmia (HP:0002521)2.44129529
41Hypothermia (HP:0002045)2.40264213
42Hemiparesis (HP:0001269)2.38674997
43Gait imbalance (HP:0002141)2.35818988
44Myelomeningocele (HP:0002475)2.32366390
45Tubulointerstitial nephritis (HP:0001970)2.27686925
46Myokymia (HP:0002411)2.27165646
47Supranuclear gaze palsy (HP:0000605)2.27115407
48Genital tract atresia (HP:0001827)2.24813347
49Abnormality of the labia minora (HP:0012880)2.22489907
50Limb dystonia (HP:0002451)2.21574948
51Vaginal atresia (HP:0000148)2.21451369
52Absent eyebrow (HP:0002223)2.20774105
53Albinism (HP:0001022)2.19930086
54Intellectual disability, moderate (HP:0002342)2.18882611
55Aplasia/Hypoplasia of the tibia (HP:0005772)2.18539298
56Optic nerve hypoplasia (HP:0000609)2.18228631
57Morphological abnormality of the middle ear (HP:0008609)2.18015580
58Renal hypoplasia (HP:0000089)2.17858554
59Alacrima (HP:0000522)2.13380119
60Abnormality of the 4th metacarpal (HP:0010012)2.12886430
61Central scotoma (HP:0000603)2.12780915
62Type II lissencephaly (HP:0007260)2.12440440
63Abnormal hair whorl (HP:0010721)2.11586494
64Abnormality of the nasolacrimal system (HP:0000614)2.11485989
65Progressive cerebellar ataxia (HP:0002073)2.11062262
66Microglossia (HP:0000171)2.09984385
67Cystic liver disease (HP:0006706)2.08316631
68Abnormality of the phalanges of the hallux (HP:0010057)2.08225330
69Long nose (HP:0003189)2.07688821
70Akinesia (HP:0002304)2.06671535
71Absent speech (HP:0001344)2.05141684
72Retinal dysplasia (HP:0007973)2.04651225
73Bifid tongue (HP:0010297)2.03774191
74Gastrointestinal atresia (HP:0002589)2.01279705
75Narrow forehead (HP:0000341)1.97386556
76Abnormal eating behavior (HP:0100738)1.96056665
77Postaxial hand polydactyly (HP:0001162)1.95703402
78Decreased lacrimation (HP:0000633)1.94722968
79Ankle clonus (HP:0011448)1.93221086
80Epidermoid cyst (HP:0200040)1.93177247
81Aplasia/Hypoplasia of the brainstem (HP:0007362)1.91274738
82Hypoplasia of the brainstem (HP:0002365)1.91274738
83Renal duplication (HP:0000075)1.89797981
84Absence seizures (HP:0002121)1.89657093
85Bony spicule pigmentary retinopathy (HP:0007737)1.88365727
86Spastic gait (HP:0002064)1.86460493
87Genetic anticipation (HP:0003743)1.86193434
88Aplasia/Hypoplasia of the macula (HP:0008059)1.86175766
89Medial flaring of the eyebrow (HP:0010747)1.84857871
90Spastic tetraplegia (HP:0002510)1.84726728
91Abnormality of incisor morphology (HP:0011063)1.84639798
92Tubular atrophy (HP:0000092)1.84322202
93Attenuation of retinal blood vessels (HP:0007843)1.84189594
94Mutism (HP:0002300)1.84174828
95Oligodactyly (hands) (HP:0001180)1.83490858
96Progressive inability to walk (HP:0002505)1.83119642
97Action tremor (HP:0002345)1.82860482
98Protruding tongue (HP:0010808)1.82624006
99Anophthalmia (HP:0000528)1.82417779
100Urinary bladder sphincter dysfunction (HP:0002839)1.82240444
101Poor coordination (HP:0002370)1.81439820
102Esotropia (HP:0000565)1.81383806
103Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.81298962
104Anencephaly (HP:0002323)1.79313439
105Anteriorly placed anus (HP:0001545)1.79060152
106Exotropia (HP:0000577)1.78967565
107Abnormality of salivation (HP:0100755)1.77982336
108Abnormality of the lacrimal duct (HP:0011481)1.77735906
109Abnormality of the parietal bone (HP:0002696)1.77401685
110Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.77053830
111Amblyopia (HP:0000646)1.76535266
112Ulnar claw (HP:0001178)1.76200790
113Polydipsia (HP:0001959)1.76034082
114Abnormal drinking behavior (HP:0030082)1.76034082
115Omphalocele (HP:0001539)1.75364829
116Dialeptic seizures (HP:0011146)1.75137380
117Asymmetry of the thorax (HP:0001555)1.75099146
118Specific learning disability (HP:0001328)1.74543048
119Sacral dimple (HP:0000960)1.74510138
120Lissencephaly (HP:0001339)1.73755606
121Tubulointerstitial abnormality (HP:0001969)1.73536352
122Congenital sensorineural hearing impairment (HP:0008527)1.73005625
123Thyroid-stimulating hormone excess (HP:0002925)1.72989809
124Short tibia (HP:0005736)1.72421427
125Sclerocornea (HP:0000647)1.72419057
126Congenital primary aphakia (HP:0007707)1.72266956
127Aplasia/Hypoplasia affecting the retina (HP:0008061)1.71899037
128Aplasia/Hypoplasia of the tongue (HP:0010295)1.71883827
129Volvulus (HP:0002580)1.71419343
130Methylmalonic acidemia (HP:0002912)1.71119569
131Inappropriate behavior (HP:0000719)1.71062994
132High anterior hairline (HP:0009890)1.69954995
133Postaxial foot polydactyly (HP:0001830)1.69538062
134Meningocele (HP:0002435)1.68589627
135Heterochromia iridis (HP:0001100)1.68142399
136Gastroesophageal reflux (HP:0002020)1.68061690
137Coronal craniosynostosis (HP:0004440)1.67442270
138Cupped ear (HP:0000378)1.67433800
139Generalized tonic-clonic seizures (HP:0002069)1.66143682
140Epileptiform EEG discharges (HP:0011182)1.66018528
141Pachygyria (HP:0001302)1.65490936
142Neurofibrillary tangles (HP:0002185)1.65222075
143Gaze-evoked nystagmus (HP:0000640)1.64822591
144Visual hallucinations (HP:0002367)1.64677217
145Amyotrophic lateral sclerosis (HP:0007354)1.64470082
146Nephronophthisis (HP:0000090)1.64018150
147Nephrogenic diabetes insipidus (HP:0009806)1.63897987
148EEG with generalized epileptiform discharges (HP:0011198)1.62025229
149Atelectasis (HP:0100750)1.61733635
150Polyphagia (HP:0002591)1.61546293
151Downturned corners of mouth (HP:0002714)1.59725990
152Atrioventricular canal defect (HP:0006695)1.59700604
153Hyperthyroidism (HP:0000836)1.59362813
154Partial agenesis of the corpus callosum (HP:0001338)1.58666441
155Impaired vibration sensation in the lower limbs (HP:0002166)1.58555991
156Urinary urgency (HP:0000012)1.57742882
157Ectopic anus (HP:0004397)1.57055228
158Cerebral inclusion bodies (HP:0100314)1.56521432

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.19544378
2FRK4.38778364
3CASK3.44144270
4NTRK33.14203109
5EPHA42.86756390
6TNIK2.64470287
7MAPK132.58540909
8MAP4K22.46202891
9MAP3K42.44638807
10DYRK22.29687889
11MAP2K72.29551564
12ERBB32.22834759
13PRPF4B2.14501968
14BCR1.94946861
15INSRR1.93555465
16NTRK21.84038513
17PINK11.75353042
18PLK21.71628953
19MINK11.70609485
20STK391.66580214
21SIK21.61425538
22OXSR11.58657414
23KSR11.55729154
24PKN11.53410476
25ADRBK21.49927941
26CSNK1A1L1.43757841
27UHMK11.38542545
28PHKG21.35908604
29PHKG11.35908604
30PAK61.35680213
31BRD41.35405060
32PNCK1.33726413
33CSNK1G31.31508719
34CSNK1G21.30519613
35EPHB21.27895158
36GRK11.24779814
37DYRK1A1.13527875
38MAP3K91.11607529
39MKNK11.11163351
40LATS21.10334943
41CSNK1G11.08548066
42BMPR1B1.07772135
43TRIM281.07488766
44SIK31.07183685
45SGK2231.05344230
46SGK4941.05344230
47MAP2K41.01564553
48DAPK21.01072742
49CDK51.00896258
50MARK20.97857396
51CDK190.97710192
52AKT30.95225270
53WNK30.94743494
54CAMKK20.94037984
55LIMK10.92520228
56ICK0.89457979
57DYRK30.87682894
58STK38L0.82987270
59MKNK20.82123523
60CAMK2B0.79307931
61BMPR20.79188643
62CAMK2A0.78277331
63LATS10.76513818
64SGK20.74020115
65ACVR1B0.73253918
66IRAK20.72957458
67CDK180.71084131
68PRKCG0.70783131
69CDK140.70617857
70TYRO30.70012540
71TAOK10.69951373
72PAK30.69733247
73DDR20.68793480
74MAP3K60.67826693
75CDK150.65030125
76CAMK1G0.64888029
77PRKCE0.64088660
78EPHA30.63775675
79FGFR20.61807085
80GRK50.61473421
81ERBB40.61013681
82TLK10.60166354
83PLK40.57705674
84YES10.56722182
85PRKCZ0.56496441
86ROCK20.55947770
87CDK11A0.55620710
88FGR0.55486019
89SGK10.55379944
90CDK30.55202289
91PTK2B0.54597512
92WNK10.53464022
93PRKACA0.51879336
94NEK60.48566496
95PLK30.48078500
96ERBB20.48019800
97MAP3K20.46897716
98CSNK1A10.46749688
99STK110.45918625
100ZAK0.42943139
101RPS6KA20.42607274
102CSNK1D0.42607007
103PRKD30.41976910
104PRKACB0.41886912
105ADRBK10.41438809
106MAPK80.41423204
107NTRK10.40988791
108CAMK10.40875882
109CAMKK10.40010121
110CSNK1E0.38653030
111PRKAA10.38039398
112DYRK1B0.37808199
113CAMK40.37716747
114GSK3B0.37301707
115PRKG10.37298629
116MAPK90.37232626
117OBSCN0.36934390
118SGK30.36898155
119WNK40.36731057
120EIF2AK20.36366607
121CAMK2D0.36248288
122PRKCH0.35569638
123ROCK10.35433057
124FER0.35031042
125RPS6KB10.30579143
126TIE10.30001092
127RPS6KA30.28931079
128PRKCB0.28654669
129CCNB10.24970442
130MAPK150.23685367

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.49575200
2Axon guidance_Homo sapiens_hsa043603.10216160
3Maturity onset diabetes of the young_Homo sapiens_hsa049502.48015151
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.39639029
5Glutamatergic synapse_Homo sapiens_hsa047242.27476018
6GABAergic synapse_Homo sapiens_hsa047272.13901830
7Morphine addiction_Homo sapiens_hsa050322.11264023
8Circadian entrainment_Homo sapiens_hsa047132.09175499
9Serotonergic synapse_Homo sapiens_hsa047261.97814781
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.96086004
11Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.88943022
12Synaptic vesicle cycle_Homo sapiens_hsa047211.88080372
13Olfactory transduction_Homo sapiens_hsa047401.87830862
14Taste transduction_Homo sapiens_hsa047421.86090258
15Dopaminergic synapse_Homo sapiens_hsa047281.85130766
16Butanoate metabolism_Homo sapiens_hsa006501.83096153
17Long-term potentiation_Homo sapiens_hsa047201.80641588
18Hedgehog signaling pathway_Homo sapiens_hsa043401.72366759
19Long-term depression_Homo sapiens_hsa047301.61906774
20Basal cell carcinoma_Homo sapiens_hsa052171.61368312
21Cholinergic synapse_Homo sapiens_hsa047251.61031690
22Amphetamine addiction_Homo sapiens_hsa050311.58827685
23Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.50446048
24Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.45631485
25ErbB signaling pathway_Homo sapiens_hsa040121.41855347
26Gap junction_Homo sapiens_hsa045401.40258658
27Wnt signaling pathway_Homo sapiens_hsa043101.39155772
28Renin secretion_Homo sapiens_hsa049241.37497353
29Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.35253089
30Cocaine addiction_Homo sapiens_hsa050301.33104447
31Melanogenesis_Homo sapiens_hsa049161.32682881
32Phototransduction_Homo sapiens_hsa047441.30640268
33Salivary secretion_Homo sapiens_hsa049701.28434494
34Steroid biosynthesis_Homo sapiens_hsa001001.24516986
35Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.22175113
36Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.21975825
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.21674980
38Oxytocin signaling pathway_Homo sapiens_hsa049211.20494906
39Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.17678579
40Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.17636930
41Protein export_Homo sapiens_hsa030601.16925195
42Insulin secretion_Homo sapiens_hsa049111.12166003
43Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.11764308
44Calcium signaling pathway_Homo sapiens_hsa040201.10655308
45Linoleic acid metabolism_Homo sapiens_hsa005911.10052042
46GnRH signaling pathway_Homo sapiens_hsa049121.08254373
47Regulation of autophagy_Homo sapiens_hsa041401.08141168
48Hippo signaling pathway_Homo sapiens_hsa043901.07764497
49Aldosterone synthesis and secretion_Homo sapiens_hsa049251.04163147
50Selenocompound metabolism_Homo sapiens_hsa004501.03512015
51Basal transcription factors_Homo sapiens_hsa030221.03195529
52Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.01416890
53Cardiac muscle contraction_Homo sapiens_hsa042601.01024404
54alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.00238781
55Colorectal cancer_Homo sapiens_hsa052101.00107328
56Endometrial cancer_Homo sapiens_hsa052130.98644273
57Gastric acid secretion_Homo sapiens_hsa049710.98194925
58Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.96870215
59Collecting duct acid secretion_Homo sapiens_hsa049660.95732178
60Ras signaling pathway_Homo sapiens_hsa040140.92765260
61Renal cell carcinoma_Homo sapiens_hsa052110.92658302
62Nitrogen metabolism_Homo sapiens_hsa009100.92637290
63cAMP signaling pathway_Homo sapiens_hsa040240.91861005
64Dorso-ventral axis formation_Homo sapiens_hsa043200.89805550
65Ether lipid metabolism_Homo sapiens_hsa005650.89547862
66Glioma_Homo sapiens_hsa052140.88564652
67Circadian rhythm_Homo sapiens_hsa047100.88142461
68Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.88052807
69Oocyte meiosis_Homo sapiens_hsa041140.87732566
70MAPK signaling pathway_Homo sapiens_hsa040100.86591609
71Alcoholism_Homo sapiens_hsa050340.86506391
72Alzheimers disease_Homo sapiens_hsa050100.86303786
73Dilated cardiomyopathy_Homo sapiens_hsa054140.85589976
74Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.85472425
75Type II diabetes mellitus_Homo sapiens_hsa049300.85312613
76beta-Alanine metabolism_Homo sapiens_hsa004100.81341831
77Propanoate metabolism_Homo sapiens_hsa006400.80799715
78Tryptophan metabolism_Homo sapiens_hsa003800.79940902
79Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.79431037
80ABC transporters_Homo sapiens_hsa020100.78677622
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.75978748
82Oxidative phosphorylation_Homo sapiens_hsa001900.75713756
83Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.75443884
84Estrogen signaling pathway_Homo sapiens_hsa049150.73988389
85Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.73101758
86cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73000200
87Tight junction_Homo sapiens_hsa045300.72935449
88Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.72585553
89Vascular smooth muscle contraction_Homo sapiens_hsa042700.72252933
90Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.71853848
91Steroid hormone biosynthesis_Homo sapiens_hsa001400.70245038
92Melanoma_Homo sapiens_hsa052180.68959685
93Vibrio cholerae infection_Homo sapiens_hsa051100.68390324
94Choline metabolism in cancer_Homo sapiens_hsa052310.67755363
95Rap1 signaling pathway_Homo sapiens_hsa040150.66857675
96Phospholipase D signaling pathway_Homo sapiens_hsa040720.66316481
97Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.64149082
98Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.63194690
99Caffeine metabolism_Homo sapiens_hsa002320.63059864
100Primary bile acid biosynthesis_Homo sapiens_hsa001200.62975412
101MicroRNAs in cancer_Homo sapiens_hsa052060.61776799
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.61598153
103Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.61560011
104Ovarian steroidogenesis_Homo sapiens_hsa049130.61056508
105Viral myocarditis_Homo sapiens_hsa054160.60144550
106Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.60052239
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59251519
108Parkinsons disease_Homo sapiens_hsa050120.58331614
109Peroxisome_Homo sapiens_hsa041460.57552404
110mRNA surveillance pathway_Homo sapiens_hsa030150.57483147
111Huntingtons disease_Homo sapiens_hsa050160.55276906
112Neurotrophin signaling pathway_Homo sapiens_hsa047220.53281907
113Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.52448349
114Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.48800698
115Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48008966
116TGF-beta signaling pathway_Homo sapiens_hsa043500.47402991
117Fanconi anemia pathway_Homo sapiens_hsa034600.47258295
118Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.47040240
119Regulation of actin cytoskeleton_Homo sapiens_hsa048100.46468022
120Prostate cancer_Homo sapiens_hsa052150.45490733
121Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.44901377
122Fatty acid biosynthesis_Homo sapiens_hsa000610.44894431
123Pathways in cancer_Homo sapiens_hsa052000.44698031
124Retinol metabolism_Homo sapiens_hsa008300.43826168
125Chemical carcinogenesis_Homo sapiens_hsa052040.41071501
126Pancreatic secretion_Homo sapiens_hsa049720.40790841
127Notch signaling pathway_Homo sapiens_hsa043300.40542590
128Thyroid hormone signaling pathway_Homo sapiens_hsa049190.40106305
129Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39271441
130Fatty acid metabolism_Homo sapiens_hsa012120.39225524
131Sulfur metabolism_Homo sapiens_hsa009200.39128385
132Sphingolipid metabolism_Homo sapiens_hsa006000.38446078
133Adherens junction_Homo sapiens_hsa045200.37936542
134Glucagon signaling pathway_Homo sapiens_hsa049220.37845368
135Bile secretion_Homo sapiens_hsa049760.37532927
136Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36708433
137PI3K-Akt signaling pathway_Homo sapiens_hsa041510.33310157

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