ATAD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.43589724
2presynaptic membrane assembly (GO:0097105)5.32522867
3synaptic vesicle exocytosis (GO:0016079)5.16910605
4neurotransmitter-gated ion channel clustering (GO:0072578)5.14485766
5synaptic vesicle docking involved in exocytosis (GO:0016081)5.10422945
6regulation of synaptic vesicle exocytosis (GO:2000300)4.77389786
7regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.73125925
8presynaptic membrane organization (GO:0097090)4.71996146
9glutamate secretion (GO:0014047)4.43773649
10vocalization behavior (GO:0071625)4.42548169
11regulation of synaptic vesicle transport (GO:1902803)4.25503342
12regulation of short-term neuronal synaptic plasticity (GO:0048172)4.17128605
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.09521679
14long-term synaptic potentiation (GO:0060291)4.06269092
15locomotory exploration behavior (GO:0035641)4.05880560
16regulation of glutamate receptor signaling pathway (GO:1900449)3.99564631
17protein localization to synapse (GO:0035418)3.96841680
18positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.96780792
19postsynaptic membrane organization (GO:0001941)3.93231613
20gamma-aminobutyric acid signaling pathway (GO:0007214)3.83224162
21membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.80739417
22neurotransmitter secretion (GO:0007269)3.78192287
23cerebellar granule cell differentiation (GO:0021707)3.74649807
24inositol phosphate catabolic process (GO:0071545)3.71857306
25positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.65043996
26ribonucleoprotein complex disassembly (GO:0032988)3.52058870
27neuron-neuron synaptic transmission (GO:0007270)3.50979096
28tricarboxylic acid cycle (GO:0006099)3.50104611
29ATP hydrolysis coupled proton transport (GO:0015991)3.46061677
30energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.46061677
31proline transport (GO:0015824)3.43531756
32positive regulation of mitochondrial fission (GO:0090141)3.38879855
33regulation of acyl-CoA biosynthetic process (GO:0050812)3.38610467
34nucleobase catabolic process (GO:0046113)3.36076424
35synaptic vesicle maturation (GO:0016188)3.34832817
36startle response (GO:0001964)3.34105059
37negative regulation of synaptic transmission, GABAergic (GO:0032229)3.33345036
38synaptic transmission, glutamatergic (GO:0035249)3.31732922
39regulation of coenzyme metabolic process (GO:0051196)3.30897968
40regulation of cofactor metabolic process (GO:0051193)3.30897968
41glutamate receptor signaling pathway (GO:0007215)3.30675981
42gonadal mesoderm development (GO:0007506)3.30021603
43cullin deneddylation (GO:0010388)3.29273876
44ionotropic glutamate receptor signaling pathway (GO:0035235)3.28875281
45exploration behavior (GO:0035640)3.28223450
46inositol phosphate dephosphorylation (GO:0046855)3.27762106
47phosphorylated carbohydrate dephosphorylation (GO:0046838)3.27762106
48regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.22369411
49NADH metabolic process (GO:0006734)3.21298608
50positive regulation of synapse maturation (GO:0090129)3.20904118
51positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.19454116
52neuronal action potential propagation (GO:0019227)3.14722045
53neuron recognition (GO:0008038)3.14574481
54succinate metabolic process (GO:0006105)3.13881021
55G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.13130144
56transferrin transport (GO:0033572)3.12230102
57* regulation of synaptic transmission, glutamatergic (GO:0051966)3.11587231
58DNA double-strand break processing (GO:0000729)3.10742437
59innervation (GO:0060384)3.09069079
60response to histamine (GO:0034776)3.05751597
61ferric iron transport (GO:0015682)3.05554330
62trivalent inorganic cation transport (GO:0072512)3.05554330
63regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.05187993
64positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.05036697
65organelle disassembly (GO:1903008)3.04203277
66gamma-aminobutyric acid transport (GO:0015812)3.01424157
67oxaloacetate metabolic process (GO:0006107)3.01075547
68vesicle transport along microtubule (GO:0047496)3.00967274
69positive regulation of membrane potential (GO:0045838)2.99546617
70protein deneddylation (GO:0000338)2.98581381
71neurotransmitter transport (GO:0006836)2.97585434
72negative regulation of neurotransmitter transport (GO:0051589)2.97369964
73synapse assembly (GO:0007416)2.95613217
74mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.94997644
75negative regulation of DNA recombination (GO:0045910)2.94869454
76layer formation in cerebral cortex (GO:0021819)2.93088230
77regulation of excitatory postsynaptic membrane potential (GO:0060079)2.90212683
78regulation of neurotransmitter secretion (GO:0046928)2.90147542
79negative regulation of neurotransmitter secretion (GO:0046929)2.85776681
80positive regulation of synaptic transmission (GO:0050806)2.84637827
81establishment of synaptic vesicle localization (GO:0097480)2.83124470
82synaptic vesicle transport (GO:0048489)2.83124470
83axonal fasciculation (GO:0007413)2.82627960
84synaptic vesicle endocytosis (GO:0048488)2.79536328
85activation of protein kinase A activity (GO:0034199)2.78608338
86regulation of postsynaptic membrane potential (GO:0060078)2.78276718
87organelle transport along microtubule (GO:0072384)2.77586446
88regulation of sulfur metabolic process (GO:0042762)2.77381089
89regulation of synaptic plasticity (GO:0048167)2.76928575
90pyrimidine nucleobase catabolic process (GO:0006208)2.76429536
91synapse organization (GO:0050808)2.76223255
92apical protein localization (GO:0045176)2.74161005
93sodium ion export (GO:0071436)2.73045929
94establishment of vesicle localization (GO:0051650)2.72510101
95regulation of neurotransmitter transport (GO:0051588)2.72025865
96ER overload response (GO:0006983)2.71679874
97regulation of neurotransmitter levels (GO:0001505)2.71152162
98positive regulation of synapse assembly (GO:0051965)2.70685607
99regulation of synapse structural plasticity (GO:0051823)2.70501969
100pyrimidine dimer repair (GO:0006290)2.69686145
101regulation of cAMP-dependent protein kinase activity (GO:2000479)2.68565904
102negative regulation of dendrite morphogenesis (GO:0050774)2.67396911
103mechanosensory behavior (GO:0007638)2.66047721
104detection of calcium ion (GO:0005513)2.65838563
105protein localization to cilium (GO:0061512)2.65762321
106positive regulation of cardiac muscle hypertrophy (GO:0010613)2.63796890
107positive regulation of muscle hypertrophy (GO:0014742)2.63796890
108regulation of dendritic spine morphogenesis (GO:0061001)2.63481268
109regulation of long-term neuronal synaptic plasticity (GO:0048169)2.62402486
110regulation of neuronal synaptic plasticity (GO:0048168)2.60973519
111righting reflex (GO:0060013)2.55928850
112glycosphingolipid biosynthetic process (GO:0006688)2.52923638
113regulation of glucokinase activity (GO:0033131)2.45922760
114regulation of hexokinase activity (GO:1903299)2.45922760
115mitotic sister chromatid cohesion (GO:0007064)2.44320657
116calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.43244143
117lipid particle organization (GO:0034389)2.38929099
118cellular ketone body metabolic process (GO:0046950)2.32385014
119double-strand break repair via nonhomologous end joining (GO:0006303)2.32298714
120non-recombinational repair (GO:0000726)2.32298714
121regulation of cell communication by electrical coupling (GO:0010649)2.31441898
122membrane budding (GO:0006900)2.31079009
123endoplasmic reticulum organization (GO:0007029)2.29981149
124spermatid nucleus differentiation (GO:0007289)2.28163013
125establishment of mitochondrion localization (GO:0051654)2.27372155
126histone H2A acetylation (GO:0043968)2.26539342
127ketone body metabolic process (GO:1902224)2.26515987
128single strand break repair (GO:0000012)2.24327682
129neural tube formation (GO:0001841)2.23009335
130ribosome assembly (GO:0042255)2.17255065
131dendrite morphogenesis (GO:0048813)2.16514427
132negative regulation of neurological system process (GO:0031645)2.16504829
133mitochondrial fission (GO:0000266)2.15817782
134establishment of melanosome localization (GO:0032401)2.15698254
135retinal cone cell development (GO:0046549)2.15562605
136acrosome reaction (GO:0007340)2.15413740
137tRNA aminoacylation for protein translation (GO:0006418)2.15140678
138intraciliary transport (GO:0042073)2.14153720
139nonmotile primary cilium assembly (GO:0035058)2.13564937
140regulation of sarcomere organization (GO:0060297)2.13467306
141regulation of growth hormone secretion (GO:0060123)2.13206174
142nuclear pore organization (GO:0006999)2.12659943
143magnesium ion transport (GO:0015693)2.12431133
144regulation of centriole replication (GO:0046599)2.12282170
145L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.11582131
146vesicle localization (GO:0051648)2.11461707
147melanosome transport (GO:0032402)2.10957921
148amino acid activation (GO:0043038)2.10908645
149tRNA aminoacylation (GO:0043039)2.10908645
150acrosome assembly (GO:0001675)2.10881367
151cytoskeleton-dependent intracellular transport (GO:0030705)2.10208421
152L-serine transport (GO:0015825)2.09910056
153neurofilament cytoskeleton organization (GO:0060052)2.09745172
154microtubule-based transport (GO:0010970)2.09100888
155peroxisome fission (GO:0016559)2.08985305
156DNA damage response, detection of DNA damage (GO:0042769)2.08383900
157positive regulation of dendritic spine morphogenesis (GO:0061003)2.07851149
158response to pheromone (GO:0019236)2.07117871
159microtubule anchoring (GO:0034453)2.07082114
160protein prenylation (GO:0018342)2.07020011
161prenylation (GO:0097354)2.07020011
162regulation of helicase activity (GO:0051095)2.06038838
163positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.04406278
164positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.04406278
165positive regulation of mitotic sister chromatid separation (GO:1901970)2.04406278
166regulation of mitotic spindle checkpoint (GO:1903504)2.04238299
167regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.04238299

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.32210994
2EZH2_22144423_ChIP-Seq_EOC_Human3.72022285
3TAF15_26573619_Chip-Seq_HEK293_Human3.46872972
4RBPJ_22232070_ChIP-Seq_NCS_Mouse3.02049852
5* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.80169450
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.69179998
7CTBP2_25329375_ChIP-Seq_LNCAP_Human2.64337504
8AR_21572438_ChIP-Seq_LNCaP_Human2.61293037
9* FUS_26573619_Chip-Seq_HEK293_Human2.59835796
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.53838171
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.30900164
12P300_19829295_ChIP-Seq_ESCs_Human2.29821781
13CTBP1_25329375_ChIP-Seq_LNCAP_Human2.24451981
14OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.21951747
15SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.20634254
16SMAD4_21799915_ChIP-Seq_A2780_Human2.17308942
17IGF1R_20145208_ChIP-Seq_DFB_Human2.15098850
18CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.12438159
19SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.10362885
20KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.09878352
21NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.04035779
22SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.03783238
23SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.94631782
24ER_23166858_ChIP-Seq_MCF-7_Human1.93695016
25PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.93556801
26SMAD_19615063_ChIP-ChIP_OVARY_Human1.92872446
27REST_21632747_ChIP-Seq_MESCs_Mouse1.92650866
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.90739112
29AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.90494699
30* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.89317788
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.86156263
32* ELK1_19687146_ChIP-ChIP_HELA_Human1.84963882
33EWS_26573619_Chip-Seq_HEK293_Human1.83565020
34PIAS1_25552417_ChIP-Seq_VCAP_Human1.83222860
35TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.81260904
36ZNF274_21170338_ChIP-Seq_K562_Hela1.78705971
37TOP2B_26459242_ChIP-Seq_MCF-7_Human1.77808721
38FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.76658355
39STAT3_23295773_ChIP-Seq_U87_Human1.74563923
40* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.74115709
41HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.73310565
42SOX2_21211035_ChIP-Seq_LN229_Gbm1.72580548
43GABP_17652178_ChIP-ChIP_JURKAT_Human1.71930006
44AR_25329375_ChIP-Seq_VCAP_Human1.71762312
45SMAD3_21741376_ChIP-Seq_EPCs_Human1.71659426
46REST_18959480_ChIP-ChIP_MESCs_Mouse1.69321514
47RARB_27405468_Chip-Seq_BRAIN_Mouse1.67525485
48SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.65802919
49SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.61814563
50PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.61807453
51NR3C1_23031785_ChIP-Seq_PC12_Mouse1.59479158
52JARID2_20064375_ChIP-Seq_MESCs_Mouse1.59195151
53VDR_22108803_ChIP-Seq_LS180_Human1.53748209
54E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.52244813
55MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.51315788
56PADI4_21655091_ChIP-ChIP_MCF-7_Human1.48872736
57WT1_19549856_ChIP-ChIP_CCG9911_Human1.48636443
58SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.47062220
59* TCF4_23295773_ChIP-Seq_U87_Human1.46794524
60JUN_21703547_ChIP-Seq_K562_Human1.46702875
61SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.46280045
62PCGF2_27294783_Chip-Seq_ESCs_Mouse1.45499618
63MTF2_20144788_ChIP-Seq_MESCs_Mouse1.44002256
64HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.43416380
65EST1_17652178_ChIP-ChIP_JURKAT_Human1.40402917
66FLI1_27457419_Chip-Seq_LIVER_Mouse1.39733015
67NANOG_18555785_Chip-Seq_ESCs_Mouse1.39267729
68SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.39178833
69EZH2_27304074_Chip-Seq_ESCs_Mouse1.39177571
70UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.38625254
71CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.38587616
72TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.37768550
73FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.33873547
74MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.32886888
75TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.32076129
76BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.31835900
77PRDM14_20953172_ChIP-Seq_ESCs_Human1.31636258
78CBP_20019798_ChIP-Seq_JUKART_Human1.31414021
79IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.31414021
80CDX2_19796622_ChIP-Seq_MESCs_Mouse1.27455850
81EZH2_27294783_Chip-Seq_NPCs_Mouse1.26651211
82KLF5_20875108_ChIP-Seq_MESCs_Mouse1.26366549
83NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.25225702
84ZNF217_24962896_ChIP-Seq_MCF-7_Human1.25160125
85RUNX2_22187159_ChIP-Seq_PCA_Human1.24642086
86BCAT_22108803_ChIP-Seq_LS180_Human1.23406468
87RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.23224627
88SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22679200
89EZH2_18974828_ChIP-Seq_MESCs_Mouse1.22092921
90RNF2_18974828_ChIP-Seq_MESCs_Mouse1.22092921
91YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.21567829
92RNF2_27304074_Chip-Seq_NSC_Mouse1.21190935
93FLI1_21867929_ChIP-Seq_TH2_Mouse1.20875926
94CREB1_15753290_ChIP-ChIP_HEK293T_Human1.20779747
95E2F1_18555785_Chip-Seq_ESCs_Mouse1.20575105
96SOX9_26525672_Chip-Seq_HEART_Mouse1.20294469
97EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.20167617
98FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.19846220
99JARID2_20075857_ChIP-Seq_MESCs_Mouse1.18977052
100YAP1_20516196_ChIP-Seq_MESCs_Mouse1.18357524
101E2F4_17652178_ChIP-ChIP_JURKAT_Human1.18350247
102PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.17872319
103REST_19997604_ChIP-ChIP_NEURONS_Mouse1.17733651
104P53_22387025_ChIP-Seq_ESCs_Mouse1.16283858
105CMYC_18555785_Chip-Seq_ESCs_Mouse1.15482266
106TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.15217081
107CBX2_27304074_Chip-Seq_ESCs_Mouse1.14687648
108EED_16625203_ChIP-ChIP_MESCs_Mouse1.13735142
109ARNT_22903824_ChIP-Seq_MCF-7_Human1.12473077
110TAL1_26923725_Chip-Seq_HPCs_Mouse1.12395124
111BMI1_23680149_ChIP-Seq_NPCS_Mouse1.12378585
112CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12214175
113HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.10934170
114EP300_21415370_ChIP-Seq_HL-1_Mouse1.10921925
115TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10711643
116NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.10600052
117NRF2_20460467_ChIP-Seq_MEFs_Mouse1.10600052
118NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10362585
119P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09956535
120PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09849254
121SUZ12_18555785_Chip-Seq_ESCs_Mouse1.09614664
122MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.08455089
123RNF2_27304074_Chip-Seq_ESCs_Mouse1.08301207
124VDR_23849224_ChIP-Seq_CD4+_Human1.07220634
125TP53_16413492_ChIP-PET_HCT116_Human1.07129264
126AR_19668381_ChIP-Seq_PC3_Human1.06920242
127TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.06376124
128KDM2B_26808549_Chip-Seq_REH_Human1.05459482
129NFE2_27457419_Chip-Seq_LIVER_Mouse1.05386226
130* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05162790
131TP53_18474530_ChIP-ChIP_U2OS_Human1.05142502
132POU5F1_16153702_ChIP-ChIP_HESCs_Human1.05070257
133* MYC_18940864_ChIP-ChIP_HL60_Human1.02064238
134KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.98841559
135CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.95965290
136IRF1_19129219_ChIP-ChIP_H3396_Human0.95295840
137GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.92955067

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.39002837
2MP0003880_abnormal_central_pattern4.33598578
3MP0003635_abnormal_synaptic_transmissio3.44655437
4MP0004270_analgesia3.37493068
5MP0009745_abnormal_behavioral_response3.00486723
6MP0002063_abnormal_learning/memory/cond2.92922169
7MP0002736_abnormal_nociception_after2.91150318
8MP0001968_abnormal_touch/_nociception2.87310324
9MP0009780_abnormal_chondrocyte_physiolo2.84976312
10MP0002064_seizures2.71573021
11MP0001529_abnormal_vocalization2.59029596
12MP0002572_abnormal_emotion/affect_behav2.56960135
13MP0002734_abnormal_mechanical_nocicepti2.45994243
14MP0005646_abnormal_pituitary_gland2.43845982
15MP0009046_muscle_twitch2.43316812
16MP0002272_abnormal_nervous_system2.34437257
17MP0003787_abnormal_imprinting2.28160058
18MP0002735_abnormal_chemical_nociception2.22680369
19MP0002102_abnormal_ear_morphology2.18587387
20MP0001984_abnormal_olfaction2.15555517
21MP0002067_abnormal_sensory_capabilities1.96685344
22MP0001501_abnormal_sleep_pattern1.93172183
23MP0001486_abnormal_startle_reflex1.88629013
24MP0004924_abnormal_behavior1.82311843
25MP0005386_behavior/neurological_phenoty1.82311843
26MP0008058_abnormal_DNA_repair1.82020996
27MP0000778_abnormal_nervous_system1.80813653
28MP0002837_dystrophic_cardiac_calcinosis1.75462460
29MP0002234_abnormal_pharynx_morphology1.70040521
30MP0003329_amyloid_beta_deposits1.68065110
31MP0003122_maternal_imprinting1.64142240
32MP0001440_abnormal_grooming_behavior1.63487395
33MP0002638_abnormal_pupillary_reflex1.63437174
34MP0004215_abnormal_myocardial_fiber1.61832333
35MP0002557_abnormal_social/conspecific_i1.61691882
36MP0002733_abnormal_thermal_nociception1.60824560
37MP0008569_lethality_at_weaning1.56046950
38MP0000013_abnormal_adipose_tissue1.55763678
39MP0006276_abnormal_autonomic_nervous1.54355534
40MP0008057_abnormal_DNA_replication1.51742720
41MP0001970_abnormal_pain_threshold1.47999981
42MP0001905_abnormal_dopamine_level1.47149706
43MP0004811_abnormal_neuron_physiology1.44653465
44MP0002822_catalepsy1.43955570
45MP0002184_abnormal_innervation1.43368149
46MP0002909_abnormal_adrenal_gland1.42243800
47MP0005253_abnormal_eye_physiology1.36131175
48MP0010386_abnormal_urinary_bladder1.35996385
49MP0005248_abnormal_Harderian_gland1.35246225
50MP0008877_abnormal_DNA_methylation1.33603809
51MP0004233_abnormal_muscle_weight1.32491715
52MP0010234_abnormal_vibrissa_follicle1.30418701
53MP0008995_early_reproductive_senescence1.30393071
54MP0005423_abnormal_somatic_nervous1.29803775
55MP0000751_myopathy1.28885351
56MP0002066_abnormal_motor_capabilities/c1.26578897
57MP0004036_abnormal_muscle_relaxation1.25243459
58MP0003567_abnormal_fetal_cardiomyocyte1.23917612
59MP0000955_abnormal_spinal_cord1.22938661
60MP0000372_irregular_coat_pigmentation1.22701276
61MP0005394_taste/olfaction_phenotype1.22332252
62MP0005499_abnormal_olfactory_system1.22332252
63MP0002882_abnormal_neuron_morphology1.22295592
64MP0004885_abnormal_endolymph1.21423576
65MP0003121_genomic_imprinting1.20736576
66MP0003879_abnormal_hair_cell1.20171807
67MP0004043_abnormal_pH_regulation1.19687697
68MP0004084_abnormal_cardiac_muscle1.18646076
69MP0001177_atelectasis1.17819283
70MP0003937_abnormal_limbs/digits/tail_de1.17566415
71MP0002876_abnormal_thyroid_physiology1.16724423
72MP0005187_abnormal_penis_morphology1.16090144
73MP0002233_abnormal_nose_morphology1.15499274
74MP0005551_abnormal_eye_electrophysiolog1.15267011
75MP0010094_abnormal_chromosome_stability1.11978252
76MP0004085_abnormal_heartbeat1.11014120
77MP0003119_abnormal_digestive_system1.10700334
78MP0004858_abnormal_nervous_system1.10249548
79MP0004133_heterotaxia1.10109537
80MP0001188_hyperpigmentation1.09338146
81MP0004142_abnormal_muscle_tone1.06835070
82MP0009697_abnormal_copulation1.06295432
83MP0002751_abnormal_autonomic_nervous1.04624687
84MP0002229_neurodegeneration1.04550669
85MP0003633_abnormal_nervous_system1.03860439
86MP0001502_abnormal_circadian_rhythm1.03510647
87MP0003631_nervous_system_phenotype1.01762075
88MP0000516_abnormal_urinary_system1.01001645
89MP0005367_renal/urinary_system_phenotyp1.01001645
90MP0008789_abnormal_olfactory_epithelium1.00531854
91MP0002090_abnormal_vision0.99700446
92MP0004484_altered_response_of0.99027817
93MP0003646_muscle_fatigue0.99023488
94MP0005645_abnormal_hypothalamus_physiol0.98765940
95MP0002152_abnormal_brain_morphology0.98462239
96MP0003786_premature_aging0.97783909
97MP0008932_abnormal_embryonic_tissue0.96621287
98MP0003632_abnormal_nervous_system0.93766085
99MP0000647_abnormal_sebaceous_gland0.92335996
100MP0003183_abnormal_peptide_metabolism0.92064064
101MP0000604_amyloidosis0.90636713
102MP0004130_abnormal_muscle_cell0.90321084
103MP0003137_abnormal_impulse_conducting0.89377638
104MP0000569_abnormal_digit_pigmentation0.89052563
105MP0000631_abnormal_neuroendocrine_gland0.88588398
106MP0002177_abnormal_outer_ear0.87533605
107MP0004147_increased_porphyrin_level0.87177803
108MP0003890_abnormal_embryonic-extraembry0.86778553
109MP0002069_abnormal_eating/drinking_beha0.86257962
110MP0003941_abnormal_skin_development0.84950844
111MP0003718_maternal_effect0.84828536
112MP0006072_abnormal_retinal_apoptosis0.83497550
113MP0003634_abnormal_glial_cell0.83305553
114MP0003123_paternal_imprinting0.81757800
115MP0003385_abnormal_body_wall0.81506297
116MP0002697_abnormal_eye_size0.81311354
117MP0002269_muscular_atrophy0.80405619
118MP0003755_abnormal_palate_morphology0.80107478
119MP0002752_abnormal_somatic_nervous0.79244972
120MP0002160_abnormal_reproductive_system0.78754439
121MP0000537_abnormal_urethra_morphology0.78478932
122MP0002009_preneoplasia0.77156717
123MP0001963_abnormal_hearing_physiology0.76697796
124MP0001286_abnormal_eye_development0.76596277
125MP0004197_abnormal_fetal_growth/weight/0.76248094
126MP0001299_abnormal_eye_distance/0.76001816
127MP0003690_abnormal_glial_cell0.75658191
128MP0005620_abnormal_muscle_contractility0.73043403
129MP0000920_abnormal_myelination0.71270460
130MP0004145_abnormal_muscle_electrophysio0.71202859
131MP0002972_abnormal_cardiac_muscle0.70986361
132MP0001485_abnormal_pinna_reflex0.70495341
133MP0005535_abnormal_body_temperature0.69029680
134MP0002078_abnormal_glucose_homeostasis0.66835212
135MP0003221_abnormal_cardiomyocyte_apopto0.66757041
136MP0001664_abnormal_digestion0.65964572
137MP0008775_abnormal_heart_ventricle0.65322786
138MP0006035_abnormal_mitochondrial_morpho0.64252830

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.76940319
2Atonic seizures (HP:0010819)5.07792556
3Epileptic encephalopathy (HP:0200134)4.79501012
4Hyperventilation (HP:0002883)4.67996659
5Pheochromocytoma (HP:0002666)4.05835987
6Neuroendocrine neoplasm (HP:0100634)3.88212318
7Absence seizures (HP:0002121)3.72816339
8Visual hallucinations (HP:0002367)3.52078923
9Increased serum pyruvate (HP:0003542)3.44183950
10Abnormality of glycolysis (HP:0004366)3.44183950
11Focal seizures (HP:0007359)3.43649777
12Febrile seizures (HP:0002373)3.27022281
13Insidious onset (HP:0003587)3.23818387
14Termporal pattern (HP:0011008)3.23818387
15Dialeptic seizures (HP:0011146)3.22968721
16Generalized tonic-clonic seizures (HP:0002069)3.22415819
17Abnormal hair whorl (HP:0010721)3.19621732
18Gait imbalance (HP:0002141)3.12939167
19Excessive salivation (HP:0003781)3.11249007
20Drooling (HP:0002307)3.11249007
21Papillary thyroid carcinoma (HP:0002895)3.10785184
22Impaired vibration sensation in the lower limbs (HP:0002166)3.04214782
23Myokymia (HP:0002411)2.94558162
24Progressive inability to walk (HP:0002505)2.85794371
25Broad-based gait (HP:0002136)2.84325810
26Medial flaring of the eyebrow (HP:0010747)2.82689444
27Volvulus (HP:0002580)2.82281964
28Epileptiform EEG discharges (HP:0011182)2.75842900
29Congenital primary aphakia (HP:0007707)2.74696677
30Nephrogenic diabetes insipidus (HP:0009806)2.72097976
31Progressive cerebellar ataxia (HP:0002073)2.68421420
32Abnormality of the labia minora (HP:0012880)2.61527213
33Akinesia (HP:0002304)2.61168840
34Resting tremor (HP:0002322)2.58685800
35Blue irides (HP:0000635)2.56413509
36Urinary urgency (HP:0000012)2.55032147
37EEG with generalized epileptiform discharges (HP:0011198)2.49376350
38Neoplasm of the peripheral nervous system (HP:0100007)2.47945829
39Abnormality of the corticospinal tract (HP:0002492)2.47875125
40Truncal ataxia (HP:0002078)2.47493664
41Scanning speech (HP:0002168)2.44565911
42Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.43083901
43Degeneration of the lateral corticospinal tracts (HP:0002314)2.43083901
44Hyperthyroidism (HP:0000836)2.39606160
45Abnormality of the musculature of the pelvis (HP:0001469)2.37597388
46Abnormality of the hip-girdle musculature (HP:0001445)2.37597388
47Poor suck (HP:0002033)2.37445078
48Hypsarrhythmia (HP:0002521)2.37057260
49Fetal akinesia sequence (HP:0001989)2.35063633
50Menstrual irregularities (HP:0000858)2.30166851
51Protruding tongue (HP:0010808)2.30115816
52Oligomenorrhea (HP:0000876)2.29069821
53Abnormal mitochondria in muscle tissue (HP:0008316)2.28289762
54Methylmalonic acidemia (HP:0002912)2.27676669
55Genital tract atresia (HP:0001827)2.26107785
56Depression (HP:0000716)2.22873179
57Progressive macrocephaly (HP:0004481)2.22527319
58Cortical dysplasia (HP:0002539)2.20083805
59Poor eye contact (HP:0000817)2.19569409
60Gaze-evoked nystagmus (HP:0000640)2.18109785
61Intestinal atresia (HP:0011100)2.17824277
62Poor speech (HP:0002465)2.16881614
63Inability to walk (HP:0002540)2.16373061
64Abnormal gallbladder physiology (HP:0012438)2.15760811
65Cholecystitis (HP:0001082)2.15760811
66Vaginal atresia (HP:0000148)2.14028428
67Failure to thrive in infancy (HP:0001531)2.13974089
68Poor coordination (HP:0002370)2.12883420
69Urinary bladder sphincter dysfunction (HP:0002839)2.11892387
70Dysdiadochokinesis (HP:0002075)2.11564460
71Spastic gait (HP:0002064)2.11235486
72Generalized myoclonic seizures (HP:0002123)2.11157263
73Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.10455563
74Acute necrotizing encephalopathy (HP:0006965)2.10275849
75Action tremor (HP:0002345)2.09390287
76Specific learning disability (HP:0001328)2.09212385
77Rimmed vacuoles (HP:0003805)2.08179096
78Abnormality of alanine metabolism (HP:0010916)2.07909310
79Hyperalaninemia (HP:0003348)2.07909310
80Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.07909310
81Aqueductal stenosis (HP:0002410)2.06699491
82Anxiety (HP:0000739)2.06397415
83Thyroid carcinoma (HP:0002890)2.06117286
84Lissencephaly (HP:0001339)2.05684399
85Hypoglycemic coma (HP:0001325)2.04564695
86Hyperinsulinemic hypoglycemia (HP:0000825)2.04043567
87Renal cortical cysts (HP:0000803)2.03448507
88Muscular hypotonia of the trunk (HP:0008936)2.02816722
89Agitation (HP:0000713)2.02395370
90Dysmetria (HP:0001310)2.01852148
91Abnormality of salivation (HP:0100755)1.99329447
92Exercise-induced myalgia (HP:0003738)1.97266386
93Gait ataxia (HP:0002066)1.96516509
94Abnormal social behavior (HP:0012433)1.96365281
95Impaired social interactions (HP:0000735)1.96365281
96Generalized hypopigmentation of hair (HP:0011358)1.94532173
97Amblyopia (HP:0000646)1.93901792
98Hypothermia (HP:0002045)1.92159859
99Mutism (HP:0002300)1.91340095
100Postural instability (HP:0002172)1.90895250
101Oligodactyly (hands) (HP:0001180)1.89736417
102Abnormality of binocular vision (HP:0011514)1.89543527
103Diplopia (HP:0000651)1.89543527
104Sensory axonal neuropathy (HP:0003390)1.88779833
105Abnormal eating behavior (HP:0100738)1.88489769
106Shoulder girdle muscle weakness (HP:0003547)1.87294166
107Polyphagia (HP:0002591)1.85818872
108Delayed gross motor development (HP:0002194)1.85342365
109Prominent metopic ridge (HP:0005487)1.84835026
110Acute encephalopathy (HP:0006846)1.83992017
111Short tibia (HP:0005736)1.83371466
112Abnormality of the metopic suture (HP:0005556)1.83207248
113Dysmetric saccades (HP:0000641)1.82839286
114Bradykinesia (HP:0002067)1.82643147
115Pelvic girdle muscle weakness (HP:0003749)1.82449837
116Absent speech (HP:0001344)1.81012916
117Neoplasm of the adrenal gland (HP:0100631)1.80781173
118Exercise-induced muscle cramps (HP:0003710)1.80457099
119Fair hair (HP:0002286)1.80147915
120Proximal tubulopathy (HP:0000114)1.79880739
121Limb dystonia (HP:0002451)1.79420754
122Medulloblastoma (HP:0002885)1.74197157
123Absent eyebrow (HP:0002223)1.72378611
124Unilateral renal agenesis (HP:0000122)1.71337471
125Abnormality of the astrocytes (HP:0100707)1.71243556
126Astrocytoma (HP:0009592)1.71243556
127Aplasia/Hypoplasia of the tibia (HP:0005772)1.70248168
128Labial hypoplasia (HP:0000066)1.68812384
129Pancreatic cysts (HP:0001737)1.67731041
130Pancreatic fibrosis (HP:0100732)1.67024830
131Hypoglycemic seizures (HP:0002173)1.65696848
132Increased hepatocellular lipid droplets (HP:0006565)1.65239157
133Abnormality of vitamin B metabolism (HP:0004340)1.64841241
134Spastic tetraplegia (HP:0002510)1.61047163
135True hermaphroditism (HP:0010459)1.60231652
136Hemiparesis (HP:0001269)1.58778515
137Bundle branch block (HP:0011710)1.58536174
138Pachygyria (HP:0001302)1.57793202
139Calf muscle hypertrophy (HP:0008981)1.57461071
140Postnatal microcephaly (HP:0005484)1.57390002
141Micropenis (HP:0000054)1.54651804
142Decreased testicular size (HP:0008734)1.53863819
143Atrophy/Degeneration involving motor neurons (HP:0007373)1.52659482
144Chronic hepatic failure (HP:0100626)1.52624675
145Abnormality of the lower motor neuron (HP:0002366)1.52391506
146Lower limb muscle weakness (HP:0007340)1.52362403
147Occipital encephalocele (HP:0002085)1.52141538
148Broad foot (HP:0001769)1.51928285
149Aplasia/hypoplasia of the uterus (HP:0008684)1.51910141
150Narrow forehead (HP:0000341)1.51242624
151Ketoacidosis (HP:0001993)1.51164318
152Abnormality of the calf musculature (HP:0001430)1.50995782

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.14354150
2MAP3K123.57303202
3TRIM283.48898280
4MAP3K43.45070817
5NTRK33.21604638
6MAP2K72.98506347
7PLK22.63590126
8SRPK12.52870152
9EIF2AK32.36729745
10MARK12.25334412
11EPHA42.24440235
12MAP4K22.24427948
13FRK2.21921063
14CDK192.14013892
15PDK42.09169987
16PDK32.09169987
17CCNB12.05229848
18OXSR11.99801518
19MAP2K41.92557856
20MAP3K91.91408486
21MINK11.86211621
22STK38L1.82324124
23TSSK61.62717726
24KSR11.59402066
25MKNK21.59024153
26MAPK131.57104328
27BRD41.52093863
28ERBB31.51397122
29ERBB41.49939758
30PRPF4B1.47426019
31KSR21.42988929
32NEK11.41245514
33NTRK21.40115671
34PINK11.35979724
35MKNK11.34964746
36BCR1.30749504
37OBSCN1.28173192
38SGK4941.27127961
39SGK2231.27127961
40FGFR21.25519515
41DAPK21.25396821
42AKT31.21686056
43SGK21.19818678
44DAPK11.19189767
45CSNK1G21.14473444
46SCYL21.14398913
47CDK81.14077220
48EIF2AK11.13644393
49RPS6KA41.11952360
50TNIK1.09792177
51LIMK11.07612292
52EPHA31.07362910
53WEE11.01950156
54LMTK21.01589406
55CDK51.00622475
56PHKG21.00503008
57PHKG11.00503008
58PDK20.99492266
59CAMK2A0.96892739
60PAK60.96272356
61PRKCG0.95147509
62WNK30.89126076
63TTK0.88470328
64PLK30.87909544
65CAMK2B0.87268275
66MAP3K20.87083099
67STK240.87011281
68PAK30.86397481
69PNCK0.86168761
70PLK40.80506324
71BMPR1B0.79618693
72BRAF0.79048274
73PBK0.77197086
74CDK140.76471968
75BMPR20.76313410
76SGK30.75740859
77LATS10.75359643
78PRKCH0.75088800
79CSNK1G30.75011611
80BRSK20.73812768
81CDK180.73131817
82DYRK30.71370925
83PRKCE0.69554551
84SIK30.69112311
85RET0.68267194
86CDK150.64929706
87RAF10.63848356
88CSNK1A1L0.63731902
89STK30.63473896
90ROCK20.61852444
91FGFR10.60814658
92PLK10.59149050
93SGK10.58151405
94ATM0.57459919
95ARAF0.56263586
96MAP3K60.53187936
97CAMK2D0.52821165
98CSNK1E0.52557104
99RPS6KB10.52165452
100NEK60.51044215
101MAP3K50.50537822
102INSRR0.50389546
103PIK3CA0.49659436
104PRKAA10.48748551
105NTRK10.48320497
106EIF2AK20.47783179
107CSNK1D0.47682737
108ZAK0.47517980
109CDK30.47485154
110CDC70.47436237
111DYRK1A0.45197271
112MAP3K130.44891734
113PRKACB0.44430671
114GRK10.44313322
115BCKDK0.43739141
116CDK11A0.43479329
117FER0.42915691
118CSNK1G10.42757438
119STK390.41597475
120RPS6KA30.41204679
121PDK10.39800545
122LATS20.39772158
123UHMK10.39664219
124NME10.38455492
125DYRK20.37664081
126MAP2K10.37391661
127ATR0.34931353
128ROCK10.34805075
129PRKCQ0.34633593
130PRKCB0.34091215
131CDK60.33653802
132CAMKK10.33537178
133PTK2B0.33520898
134ADRBK10.33436940
135MELK0.33221706
136MST40.32755905
137CAMKK20.32350175
138MOS0.32200157
139NUAK10.31758742
140CSNK1A10.31634510
141CAMK2G0.30806719

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.71246521
2Synaptic vesicle cycle_Homo sapiens_hsa047213.33292610
3Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.28655140
4Protein export_Homo sapiens_hsa030603.21860550
5Collecting duct acid secretion_Homo sapiens_hsa049662.65823291
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.54181235
7GABAergic synapse_Homo sapiens_hsa047272.51355636
8Olfactory transduction_Homo sapiens_hsa047402.35697927
9Long-term potentiation_Homo sapiens_hsa047202.34680143
10Morphine addiction_Homo sapiens_hsa050322.23903827
11Circadian entrainment_Homo sapiens_hsa047132.23764602
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.14972936
13Non-homologous end-joining_Homo sapiens_hsa034502.14952493
14Amphetamine addiction_Homo sapiens_hsa050312.09888616
15Vibrio cholerae infection_Homo sapiens_hsa051102.09508029
16Glutamatergic synapse_Homo sapiens_hsa047242.04527444
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.03837441
18Dopaminergic synapse_Homo sapiens_hsa047282.01557869
19Basal transcription factors_Homo sapiens_hsa030221.86287612
20Insulin secretion_Homo sapiens_hsa049111.75158088
21Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.66691644
22Long-term depression_Homo sapiens_hsa047301.64981118
23Pyruvate metabolism_Homo sapiens_hsa006201.60657732
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.59733597
25Serotonergic synapse_Homo sapiens_hsa047261.58134457
26Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.56652440
27Steroid biosynthesis_Homo sapiens_hsa001001.54345633
28Taste transduction_Homo sapiens_hsa047421.48104467
292-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.45300611
30RNA degradation_Homo sapiens_hsa030181.40850601
31Renin secretion_Homo sapiens_hsa049241.40176926
32Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.33138140
33Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.32242201
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.31775112
35Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.31601690
36Cholinergic synapse_Homo sapiens_hsa047251.31492173
37Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.31463162
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.30149627
39Salivary secretion_Homo sapiens_hsa049701.29131767
40RNA transport_Homo sapiens_hsa030131.23994267
41Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.23846758
42Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.22707105
43Cocaine addiction_Homo sapiens_hsa050301.21896132
44Gastric acid secretion_Homo sapiens_hsa049711.21184526
45Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.19085506
46Oxytocin signaling pathway_Homo sapiens_hsa049211.14106374
47Fanconi anemia pathway_Homo sapiens_hsa034601.12648222
48Mismatch repair_Homo sapiens_hsa034301.09904041
49Butanoate metabolism_Homo sapiens_hsa006501.08667440
50Oocyte meiosis_Homo sapiens_hsa041141.03833245
51Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.03763179
52Type I diabetes mellitus_Homo sapiens_hsa049401.02988876
53Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.02382941
54mRNA surveillance pathway_Homo sapiens_hsa030151.00644150
55Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.00641493
56Calcium signaling pathway_Homo sapiens_hsa040200.99564068
57Selenocompound metabolism_Homo sapiens_hsa004500.99436384
58Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.98916691
59Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.97576914
60Propanoate metabolism_Homo sapiens_hsa006400.96800340
61Aldosterone synthesis and secretion_Homo sapiens_hsa049250.96595903
62Nucleotide excision repair_Homo sapiens_hsa034200.95471918
63Oxidative phosphorylation_Homo sapiens_hsa001900.91132767
64Glucagon signaling pathway_Homo sapiens_hsa049220.90139029
65Type II diabetes mellitus_Homo sapiens_hsa049300.90102589
66cAMP signaling pathway_Homo sapiens_hsa040240.89629695
67cGMP-PKG signaling pathway_Homo sapiens_hsa040220.86782837
68RNA polymerase_Homo sapiens_hsa030200.86672063
69ErbB signaling pathway_Homo sapiens_hsa040120.85737377
70Regulation of autophagy_Homo sapiens_hsa041400.85308819
71Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.85133685
72Maturity onset diabetes of the young_Homo sapiens_hsa049500.85023560
73Gap junction_Homo sapiens_hsa045400.83576062
74Folate biosynthesis_Homo sapiens_hsa007900.83490150
75Axon guidance_Homo sapiens_hsa043600.83433965
76Glioma_Homo sapiens_hsa052140.82853520
77Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.80751827
78Spliceosome_Homo sapiens_hsa030400.79107816
79Phosphatidylinositol signaling system_Homo sapiens_hsa040700.78776037
80Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.78667960
81Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.78467772
82Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.78110132
83Cell cycle_Homo sapiens_hsa041100.77758456
84Sulfur metabolism_Homo sapiens_hsa009200.77011359
85Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.75572439
86Peroxisome_Homo sapiens_hsa041460.72758093
87Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.72723939
88GnRH signaling pathway_Homo sapiens_hsa049120.72629697
89Vitamin B6 metabolism_Homo sapiens_hsa007500.72316936
90Proteasome_Homo sapiens_hsa030500.72028491
91Carbon metabolism_Homo sapiens_hsa012000.71426734
92Colorectal cancer_Homo sapiens_hsa052100.70615996
93Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.70342349
94Estrogen signaling pathway_Homo sapiens_hsa049150.68693920
95Cardiac muscle contraction_Homo sapiens_hsa042600.67379174
96Rheumatoid arthritis_Homo sapiens_hsa053230.66396242
97Endometrial cancer_Homo sapiens_hsa052130.64150255
98Hippo signaling pathway_Homo sapiens_hsa043900.64072735
99Alzheimers disease_Homo sapiens_hsa050100.63793622
100Circadian rhythm_Homo sapiens_hsa047100.61248066
101Renal cell carcinoma_Homo sapiens_hsa052110.60241593
102Vascular smooth muscle contraction_Homo sapiens_hsa042700.59677277
103Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.59629077
104Purine metabolism_Homo sapiens_hsa002300.59221045
105Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57252903
106Biosynthesis of amino acids_Homo sapiens_hsa012300.55612752
107Huntingtons disease_Homo sapiens_hsa050160.54871255
108Thyroid hormone synthesis_Homo sapiens_hsa049180.54440411
109Dilated cardiomyopathy_Homo sapiens_hsa054140.53130624
110Phagosome_Homo sapiens_hsa041450.52940191
111MAPK signaling pathway_Homo sapiens_hsa040100.52608728
112Homologous recombination_Homo sapiens_hsa034400.52283087
113Tight junction_Homo sapiens_hsa045300.51479345
114Ovarian steroidogenesis_Homo sapiens_hsa049130.50966575
115Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.50958347
116Fatty acid metabolism_Homo sapiens_hsa012120.49651553
117Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.48493578
118Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.48030715
119Arginine and proline metabolism_Homo sapiens_hsa003300.47751882
120Parkinsons disease_Homo sapiens_hsa050120.46346422
121Dorso-ventral axis formation_Homo sapiens_hsa043200.45540308
122p53 signaling pathway_Homo sapiens_hsa041150.45053435
123Alcoholism_Homo sapiens_hsa050340.44330450
124Ras signaling pathway_Homo sapiens_hsa040140.44088657
125SNARE interactions in vesicular transport_Homo sapiens_hsa041300.43992130
126mTOR signaling pathway_Homo sapiens_hsa041500.43848126
127Metabolic pathways_Homo sapiens_hsa011000.42333515
128Hedgehog signaling pathway_Homo sapiens_hsa043400.42026285
129Melanogenesis_Homo sapiens_hsa049160.41692568
130Fatty acid elongation_Homo sapiens_hsa000620.40477396
131Cysteine and methionine metabolism_Homo sapiens_hsa002700.40337936
132Choline metabolism in cancer_Homo sapiens_hsa052310.37058931
133Carbohydrate digestion and absorption_Homo sapiens_hsa049730.36950650
134Nitrogen metabolism_Homo sapiens_hsa009100.36614458
135Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.36334344
136Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34658272
137Insulin signaling pathway_Homo sapiens_hsa049100.33822428
138Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.33259845
139Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.32982361
140Central carbon metabolism in cancer_Homo sapiens_hsa052300.32884112
141Phototransduction_Homo sapiens_hsa047440.32029211
142N-Glycan biosynthesis_Homo sapiens_hsa005100.31183459

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