

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | behavioral response to nicotine (GO:0035095) | 5.61176596 |
| 2 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 5.54109185 |
| 3 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 5.11831208 |
| 4 | magnesium ion transport (GO:0015693) | 4.62057097 |
| 5 | membrane repolarization during action potential (GO:0086011) | 4.59915591 |
| 6 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.39901809 |
| 7 | NADH dehydrogenase complex assembly (GO:0010257) | 4.39901809 |
| 8 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.39901809 |
| 9 | regulation of mesoderm development (GO:2000380) | 4.29984823 |
| 10 | fat-soluble vitamin catabolic process (GO:0042363) | 4.22072743 |
| 11 | vitamin catabolic process (GO:0009111) | 4.22072743 |
| 12 | DNA deamination (GO:0045006) | 4.13288214 |
| 13 | regulation of skeletal muscle contraction (GO:0014819) | 3.93488003 |
| 14 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.92405932 |
| 15 | sulfation (GO:0051923) | 3.90698087 |
| 16 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.87875836 |
| 17 | protein complex biogenesis (GO:0070271) | 3.83770289 |
| 18 | cellular anion homeostasis (GO:0030002) | 3.80124512 |
| 19 | regulation of membrane repolarization (GO:0060306) | 3.70953470 |
| 20 | parturition (GO:0007567) | 3.59818910 |
| 21 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.53299679 |
| 22 | cellular response to exogenous dsRNA (GO:0071360) | 3.47366038 |
| 23 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 3.30716339 |
| 24 | positive regulation of fatty acid oxidation (GO:0046321) | 3.22414908 |
| 25 | cellular response to electrical stimulus (GO:0071257) | 3.20417949 |
| 26 | negative regulation of systemic arterial blood pressure (GO:0003085) | 3.20391478 |
| 27 | membrane repolarization (GO:0086009) | 3.15564327 |
| 28 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 3.13486398 |
| 29 | indolalkylamine metabolic process (GO:0006586) | 3.10691441 |
| 30 | negative regulation of protein localization to cell surface (GO:2000009) | 3.09837385 |
| 31 | regulation of DNA endoreduplication (GO:0032875) | 3.08978606 |
| 32 | protein-cofactor linkage (GO:0018065) | 3.08785964 |
| 33 | trivalent inorganic anion homeostasis (GO:0072506) | 3.08631140 |
| 34 | phosphate ion homeostasis (GO:0055062) | 3.08631140 |
| 35 | interleukin-6-mediated signaling pathway (GO:0070102) | 3.08237127 |
| 36 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.07561725 |
| 37 | detection of light stimulus involved in visual perception (GO:0050908) | 3.07561725 |
| 38 | fucose catabolic process (GO:0019317) | 3.04215085 |
| 39 | L-fucose metabolic process (GO:0042354) | 3.04215085 |
| 40 | L-fucose catabolic process (GO:0042355) | 3.04215085 |
| 41 | ovulation cycle (GO:0042698) | 3.00805152 |
| 42 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.00643245 |
| 43 | regulation of gene silencing by miRNA (GO:0060964) | 3.00643245 |
| 44 | regulation of gene silencing by RNA (GO:0060966) | 3.00643245 |
| 45 | positive regulation of synapse maturation (GO:0090129) | 2.98008723 |
| 46 | cardiovascular system development (GO:0072358) | 2.97385065 |
| 47 | protein polyglutamylation (GO:0018095) | 2.94894832 |
| 48 | indole-containing compound catabolic process (GO:0042436) | 2.93861719 |
| 49 | indolalkylamine catabolic process (GO:0046218) | 2.93861719 |
| 50 | tryptophan catabolic process (GO:0006569) | 2.93861719 |
| 51 | positive regulation of defense response to virus by host (GO:0002230) | 2.91975328 |
| 52 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.91588198 |
| 53 | membrane depolarization during action potential (GO:0086010) | 2.88381956 |
| 54 | kynurenine metabolic process (GO:0070189) | 2.85852079 |
| 55 | DNA methylation involved in gamete generation (GO:0043046) | 2.85386940 |
| 56 | regulation of synapse maturation (GO:0090128) | 2.83139002 |
| 57 | gamma-aminobutyric acid transport (GO:0015812) | 2.79004082 |
| 58 | regulation of glomerulus development (GO:0090192) | 2.78041116 |
| 59 | response to xenobiotic stimulus (GO:0009410) | 2.77321862 |
| 60 | negative regulation of sodium ion transport (GO:0010766) | 2.75888670 |
| 61 | cellular ketone body metabolic process (GO:0046950) | 2.73644017 |
| 62 | cellular response to ATP (GO:0071318) | 2.72523169 |
| 63 | somite development (GO:0061053) | 2.68933588 |
| 64 | cell proliferation in forebrain (GO:0021846) | 2.68869694 |
| 65 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.68152800 |
| 66 | adaptation of signaling pathway (GO:0023058) | 2.68134944 |
| 67 | negative regulation of telomere maintenance (GO:0032205) | 2.67510334 |
| 68 | regulation of potassium ion transmembrane transport (GO:1901379) | 2.66936335 |
| 69 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.63071485 |
| 70 | regulation of hippo signaling (GO:0035330) | 2.62713049 |
| 71 | serotonin metabolic process (GO:0042428) | 2.61945358 |
| 72 | neuronal action potential (GO:0019228) | 2.61137360 |
| 73 | regulation of germinal center formation (GO:0002634) | 2.60224929 |
| 74 | primary amino compound metabolic process (GO:1901160) | 2.60177573 |
| 75 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.56486545 |
| 76 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.56265371 |
| 77 | regulation of cell proliferation involved in kidney development (GO:1901722) | 2.56024054 |
| 78 | rhodopsin mediated signaling pathway (GO:0016056) | 2.55689269 |
| 79 | action potential (GO:0001508) | 2.55279893 |
| 80 | response to electrical stimulus (GO:0051602) | 2.53779149 |
| 81 | indole-containing compound metabolic process (GO:0042430) | 2.52407221 |
| 82 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 2.51802703 |
| 83 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2.51802703 |
| 84 | dentate gyrus development (GO:0021542) | 2.50251100 |
| 85 | endoderm formation (GO:0001706) | 2.49160818 |
| 86 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.48755895 |
| 87 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.48199956 |
| 88 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.47981870 |
| 89 | interkinetic nuclear migration (GO:0022027) | 2.46608091 |
| 90 | interferon-gamma secretion (GO:0072643) | 2.44926712 |
| 91 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.43821598 |
| 92 | vitamin D metabolic process (GO:0042359) | 2.43658185 |
| 93 | ketone body metabolic process (GO:1902224) | 2.41788955 |
| 94 | flavonoid metabolic process (GO:0009812) | 2.40905083 |
| 95 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.40413426 |
| 96 | potassium ion import (GO:0010107) | 2.39877073 |
| 97 | regulation of female receptivity (GO:0045924) | 2.38951820 |
| 98 | regulation of action potential (GO:0098900) | 2.37219458 |
| 99 | relaxation of cardiac muscle (GO:0055119) | 2.36885422 |
| 100 | multicellular organism reproduction (GO:0032504) | 2.36577058 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.89433870 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.05971344 |
| 3 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.98336099 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.38455276 |
| 5 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.98140345 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.79873796 |
| 7 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.67629905 |
| 8 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.43019285 |
| 9 | EWS_26573619_Chip-Seq_HEK293_Human | 2.03024697 |
| 10 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.97189553 |
| 11 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.94882948 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.91380332 |
| 13 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.85288562 |
| 14 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.82316276 |
| 15 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.79836808 |
| 16 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.78791750 |
| 17 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.76903429 |
| 18 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.72039296 |
| 19 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.69717462 |
| 20 | FUS_26573619_Chip-Seq_HEK293_Human | 1.67503966 |
| 21 | P300_19829295_ChIP-Seq_ESCs_Human | 1.66904972 |
| 22 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.63815514 |
| 23 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.61913712 |
| 24 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.61081166 |
| 25 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.59592555 |
| 26 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.57368357 |
| 27 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.57217556 |
| 28 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.53278208 |
| 29 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.52318439 |
| 30 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.50392692 |
| 31 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.49927417 |
| 32 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.44511881 |
| 33 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.44494822 |
| 34 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.41465534 |
| 35 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.39662716 |
| 36 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.39425640 |
| 37 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.39050606 |
| 38 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.37607707 |
| 39 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.36323274 |
| 40 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.35764063 |
| 41 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.34353801 |
| 42 | TCF4_23295773_ChIP-Seq_U87_Human | 1.32796898 |
| 43 | AR_25329375_ChIP-Seq_VCAP_Human | 1.32791810 |
| 44 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.32006829 |
| 45 | STAT3_23295773_ChIP-Seq_U87_Human | 1.31326668 |
| 46 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.31079365 |
| 47 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.29841742 |
| 48 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.29841742 |
| 49 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.29654617 |
| 50 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.29654617 |
| 51 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.29263695 |
| 52 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.26767698 |
| 53 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.26767698 |
| 54 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.26663733 |
| 55 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.24668869 |
| 56 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.24303670 |
| 57 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.23696550 |
| 58 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.23692139 |
| 59 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.23027753 |
| 60 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.21227973 |
| 61 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.20471781 |
| 62 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.20471781 |
| 63 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.20386077 |
| 64 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.18418994 |
| 65 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.18238791 |
| 66 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.18172520 |
| 67 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.17716852 |
| 68 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.15163275 |
| 69 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.14644998 |
| 70 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.14065675 |
| 71 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.11434272 |
| 72 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.11110720 |
| 73 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.08876106 |
| 74 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.08558387 |
| 75 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.08022485 |
| 76 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.07402594 |
| 77 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.07352066 |
| 78 | NCOR_22424771_ChIP-Seq_293T_Human | 1.05453064 |
| 79 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04800896 |
| 80 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.02055586 |
| 81 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.01964275 |
| 82 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.01584828 |
| 83 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.01073636 |
| 84 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.00368902 |
| 85 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.99698337 |
| 86 | AR_20517297_ChIP-Seq_VCAP_Human | 0.99646402 |
| 87 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.99088044 |
| 88 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.98471781 |
| 89 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.97876934 |
| 90 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.96945855 |
| 91 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.96520921 |
| 92 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.96394255 |
| 93 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.96183737 |
| 94 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.94591971 |
| 95 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.93845783 |
| 96 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.93605155 |
| 97 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.92711664 |
| 98 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.92527627 |
| 99 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.92457136 |
| 100 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.92234268 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008877_abnormal_DNA_methylation | 3.05079085 |
| 2 | MP0005646_abnormal_pituitary_gland | 2.76819671 |
| 3 | MP0003646_muscle_fatigue | 2.74984639 |
| 4 | MP0002160_abnormal_reproductive_system | 2.66535296 |
| 5 | MP0004885_abnormal_endolymph | 2.55154295 |
| 6 | MP0000569_abnormal_digit_pigmentation | 2.54570306 |
| 7 | MP0004145_abnormal_muscle_electrophysio | 2.44349825 |
| 8 | MP0002837_dystrophic_cardiac_calcinosis | 2.41076885 |
| 9 | MP0001485_abnormal_pinna_reflex | 2.31949493 |
| 10 | MP0002876_abnormal_thyroid_physiology | 2.31780938 |
| 11 | MP0001968_abnormal_touch/_nociception | 2.27454515 |
| 12 | MP0005389_reproductive_system_phenotype | 2.24727472 |
| 13 | MP0003195_calcinosis | 2.03859458 |
| 14 | MP0006072_abnormal_retinal_apoptosis | 2.02899988 |
| 15 | MP0005551_abnormal_eye_electrophysiolog | 1.97374887 |
| 16 | MP0006292_abnormal_olfactory_placode | 1.96510350 |
| 17 | MP0004043_abnormal_pH_regulation | 1.89924481 |
| 18 | MP0002272_abnormal_nervous_system | 1.87727745 |
| 19 | MP0009046_muscle_twitch | 1.87652468 |
| 20 | MP0009745_abnormal_behavioral_response | 1.85764646 |
| 21 | MP0002736_abnormal_nociception_after | 1.85252093 |
| 22 | MP0008872_abnormal_physiological_respon | 1.84739608 |
| 23 | MP0002638_abnormal_pupillary_reflex | 1.77447343 |
| 24 | MP0004142_abnormal_muscle_tone | 1.77280058 |
| 25 | MP0002138_abnormal_hepatobiliary_system | 1.75548150 |
| 26 | MP0004019_abnormal_vitamin_homeostasis | 1.73538343 |
| 27 | MP0000631_abnormal_neuroendocrine_gland | 1.71943824 |
| 28 | MP0001440_abnormal_grooming_behavior | 1.70584554 |
| 29 | MP0004130_abnormal_muscle_cell | 1.67931598 |
| 30 | MP0003879_abnormal_hair_cell | 1.65163215 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.62996897 |
| 32 | MP0001986_abnormal_taste_sensitivity | 1.59656184 |
| 33 | MP0003011_delayed_dark_adaptation | 1.45374311 |
| 34 | MP0005645_abnormal_hypothalamus_physiol | 1.42866158 |
| 35 | MP0004742_abnormal_vestibular_system | 1.41620830 |
| 36 | MP0005253_abnormal_eye_physiology | 1.40805561 |
| 37 | MP0001919_abnormal_reproductive_system | 1.39812931 |
| 38 | MP0002102_abnormal_ear_morphology | 1.37121865 |
| 39 | MP0004133_heterotaxia | 1.35752270 |
| 40 | MP0002064_seizures | 1.34933765 |
| 41 | MP0004215_abnormal_myocardial_fiber | 1.34530817 |
| 42 | MP0001765_abnormal_ion_homeostasis | 1.28130398 |
| 43 | MP0001764_abnormal_homeostasis | 1.27302163 |
| 44 | MP0000230_abnormal_systemic_arterial | 1.26250364 |
| 45 | MP0001501_abnormal_sleep_pattern | 1.25024365 |
| 46 | MP0002234_abnormal_pharynx_morphology | 1.23400239 |
| 47 | MP0005174_abnormal_tail_pigmentation | 1.22624410 |
| 48 | MP0002653_abnormal_ependyma_morphology | 1.20811767 |
| 49 | MP0002572_abnormal_emotion/affect_behav | 1.19764918 |
| 50 | MP0005084_abnormal_gallbladder_morpholo | 1.19716572 |
| 51 | MP0001486_abnormal_startle_reflex | 1.16497889 |
| 52 | MP0006276_abnormal_autonomic_nervous | 1.14618019 |
| 53 | MP0002735_abnormal_chemical_nociception | 1.14150457 |
| 54 | MP0003718_maternal_effect | 1.12010171 |
| 55 | MP0008775_abnormal_heart_ventricle | 1.09594848 |
| 56 | MP0001905_abnormal_dopamine_level | 1.08355299 |
| 57 | MP0000013_abnormal_adipose_tissue | 1.07183230 |
| 58 | MP0002733_abnormal_thermal_nociception | 1.06802008 |
| 59 | MP0002557_abnormal_social/conspecific_i | 1.05663396 |
| 60 | MP0002938_white_spotting | 1.05521334 |
| 61 | MP0002928_abnormal_bile_duct | 1.04608431 |
| 62 | MP0000049_abnormal_middle_ear | 1.02118314 |
| 63 | MP0003635_abnormal_synaptic_transmissio | 1.01310287 |
| 64 | MP0002063_abnormal_learning/memory/cond | 1.01041826 |
| 65 | MP0001542_abnormal_bone_strength | 1.00658974 |
| 66 | MP0000026_abnormal_inner_ear | 1.00492360 |
| 67 | MP0001970_abnormal_pain_threshold | 0.99890382 |
| 68 | MP0003787_abnormal_imprinting | 0.99784547 |
| 69 | MP0002089_abnormal_postnatal_growth/wei | 0.99383436 |
| 70 | MP0010386_abnormal_urinary_bladder | 0.96622983 |
| 71 | MP0003880_abnormal_central_pattern | 0.95600197 |
| 72 | MP0001963_abnormal_hearing_physiology | 0.95154457 |
| 73 | MP0004085_abnormal_heartbeat | 0.95067043 |
| 74 | MP0001502_abnormal_circadian_rhythm | 0.92290719 |
| 75 | MP0003119_abnormal_digestive_system | 0.91953257 |
| 76 | MP0005671_abnormal_response_to | 0.91816354 |
| 77 | MP0005332_abnormal_amino_acid | 0.91547616 |
| 78 | MP0002163_abnormal_gland_morphology | 0.90775879 |
| 79 | MP0002067_abnormal_sensory_capabilities | 0.90223451 |
| 80 | MP0000427_abnormal_hair_cycle | 0.87584931 |
| 81 | MP0005195_abnormal_posterior_eye | 0.86183485 |
| 82 | MP0002909_abnormal_adrenal_gland | 0.85844405 |
| 83 | MP0002184_abnormal_innervation | 0.84879579 |
| 84 | MP0009780_abnormal_chondrocyte_physiolo | 0.83474732 |
| 85 | MP0003136_yellow_coat_color | 0.82295231 |
| 86 | MP0009250_abnormal_appendicular_skeleto | 0.81439680 |
| 87 | MP0002752_abnormal_somatic_nervous | 0.80973217 |
| 88 | MP0000383_abnormal_hair_follicle | 0.80631922 |
| 89 | MP0005386_behavior/neurological_phenoty | 0.79506596 |
| 90 | MP0004924_abnormal_behavior | 0.79506596 |
| 91 | MP0003937_abnormal_limbs/digits/tail_de | 0.77955077 |
| 92 | MP0002277_abnormal_respiratory_mucosa | 0.77397638 |
| 93 | MP0003938_abnormal_ear_development | 0.76858289 |
| 94 | MP0001756_abnormal_urination | 0.76373878 |
| 95 | MP0005410_abnormal_fertilization | 0.74658871 |
| 96 | MP0009053_abnormal_anal_canal | 0.74548791 |
| 97 | MP0001188_hyperpigmentation | 0.74035942 |
| 98 | MP0002229_neurodegeneration | 0.73882675 |
| 99 | MP0002693_abnormal_pancreas_physiology | 0.73485729 |
| 100 | MP0003567_abnormal_fetal_cardiomyocyte | 0.71741574 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chronic hepatic failure (HP:0100626) | 4.75145862 |
| 2 | Congenital stationary night blindness (HP:0007642) | 3.77388819 |
| 3 | Decreased circulating renin level (HP:0003351) | 3.50232358 |
| 4 | Osteomalacia (HP:0002749) | 3.48210652 |
| 5 | Pancreatic cysts (HP:0001737) | 3.47806327 |
| 6 | Abolished electroretinogram (ERG) (HP:0000550) | 3.34742749 |
| 7 | Molar tooth sign on MRI (HP:0002419) | 3.21852329 |
| 8 | Abnormality of midbrain morphology (HP:0002418) | 3.21852329 |
| 9 | Nephronophthisis (HP:0000090) | 3.08337856 |
| 10 | Pancreatic fibrosis (HP:0100732) | 3.07711760 |
| 11 | Clumsiness (HP:0002312) | 3.03585081 |
| 12 | Congenital, generalized hypertrichosis (HP:0004540) | 2.97165019 |
| 13 | Genetic anticipation (HP:0003743) | 2.92558389 |
| 14 | Abnormality of alanine metabolism (HP:0010916) | 2.86693114 |
| 15 | Hyperalaninemia (HP:0003348) | 2.86693114 |
| 16 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.86693114 |
| 17 | Progressive cerebellar ataxia (HP:0002073) | 2.83495885 |
| 18 | True hermaphroditism (HP:0010459) | 2.82629209 |
| 19 | Abnormality of the renal cortex (HP:0011035) | 2.81258743 |
| 20 | Abnormality of the renal medulla (HP:0100957) | 2.65881619 |
| 21 | Abnormality of the renal collecting system (HP:0004742) | 2.62760527 |
| 22 | Abnormal number of erythroid precursors (HP:0012131) | 2.62189172 |
| 23 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.61422410 |
| 24 | Fibular aplasia (HP:0002990) | 2.54896992 |
| 25 | Short hallux (HP:0010109) | 2.50380871 |
| 26 | Polydipsia (HP:0001959) | 2.47200242 |
| 27 | Abnormal drinking behavior (HP:0030082) | 2.47200242 |
| 28 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.46824419 |
| 29 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.42668947 |
| 30 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.40069248 |
| 31 | Broad-based gait (HP:0002136) | 2.39499209 |
| 32 | Hypoplasia of the uterus (HP:0000013) | 2.38627801 |
| 33 | Pendular nystagmus (HP:0012043) | 2.38453788 |
| 34 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.38065512 |
| 35 | Gaze-evoked nystagmus (HP:0000640) | 2.34781546 |
| 36 | Vascular calcification (HP:0004934) | 2.33275209 |
| 37 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.31425879 |
| 38 | Type II lissencephaly (HP:0007260) | 2.31182826 |
| 39 | Medial flaring of the eyebrow (HP:0010747) | 2.30513056 |
| 40 | Renal cortical cysts (HP:0000803) | 2.27614841 |
| 41 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.23444147 |
| 42 | Methylmalonic acidemia (HP:0002912) | 2.23349059 |
| 43 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.23039215 |
| 44 | Attenuation of retinal blood vessels (HP:0007843) | 2.22329143 |
| 45 | Decreased central vision (HP:0007663) | 2.18554122 |
| 46 | Small hand (HP:0200055) | 2.16962830 |
| 47 | Abnormality of renal excretion (HP:0011036) | 2.16838546 |
| 48 | Acute necrotizing encephalopathy (HP:0006965) | 2.16823480 |
| 49 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.16435153 |
| 50 | Furrowed tongue (HP:0000221) | 2.16053333 |
| 51 | Adactyly (HP:0009776) | 2.14488377 |
| 52 | Stenosis of the external auditory canal (HP:0000402) | 2.14389358 |
| 53 | Hypoplasia of the pons (HP:0012110) | 2.14242930 |
| 54 | Congenital sensorineural hearing impairment (HP:0008527) | 2.13923650 |
| 55 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.09858463 |
| 56 | Hypoplasia of the ulna (HP:0003022) | 2.09760894 |
| 57 | Tubular atrophy (HP:0000092) | 2.08819905 |
| 58 | Cystic liver disease (HP:0006706) | 2.08012356 |
| 59 | Metabolic alkalosis (HP:0200114) | 2.07522368 |
| 60 | Abnormality of renal resorption (HP:0011038) | 2.07085101 |
| 61 | 3-Methylglutaconic aciduria (HP:0003535) | 2.06947284 |
| 62 | Short 1st metacarpal (HP:0010034) | 2.05748706 |
| 63 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 2.05748706 |
| 64 | Large for gestational age (HP:0001520) | 2.05745826 |
| 65 | Abnormality of the pons (HP:0007361) | 2.05531112 |
| 66 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.05482744 |
| 67 | Mitochondrial inheritance (HP:0001427) | 2.02898992 |
| 68 | Increased corneal curvature (HP:0100692) | 2.02689155 |
| 69 | Keratoconus (HP:0000563) | 2.02689155 |
| 70 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.01481049 |
| 71 | Absent/shortened dynein arms (HP:0200106) | 2.01321543 |
| 72 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.01321543 |
| 73 | Hyperventilation (HP:0002883) | 1.99725147 |
| 74 | Short tibia (HP:0005736) | 1.98278315 |
| 75 | Patellar aplasia (HP:0006443) | 1.95899430 |
| 76 | Abnormality of renin-angiotensin system (HP:0000847) | 1.95731673 |
| 77 | Chorioretinal atrophy (HP:0000533) | 1.94791388 |
| 78 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.92830427 |
| 79 | Progressive macrocephaly (HP:0004481) | 1.91866780 |
| 80 | Short femoral neck (HP:0100864) | 1.90962555 |
| 81 | Cardiovascular calcification (HP:0011915) | 1.89564634 |
| 82 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.89392701 |
| 83 | Absent thumb (HP:0009777) | 1.89105308 |
| 84 | Increased CSF lactate (HP:0002490) | 1.84497127 |
| 85 | Polyuria (HP:0000103) | 1.83938103 |
| 86 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.83747989 |
| 87 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.82406832 |
| 88 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.82304635 |
| 89 | Concave nail (HP:0001598) | 1.81991840 |
| 90 | Asplenia (HP:0001746) | 1.81794219 |
| 91 | Oligodontia (HP:0000677) | 1.81494757 |
| 92 | Inability to walk (HP:0002540) | 1.80111590 |
| 93 | Abnormality of the nasal septum (HP:0000419) | 1.79019374 |
| 94 | Thyroid-stimulating hormone excess (HP:0002925) | 1.78854861 |
| 95 | Methylmalonic aciduria (HP:0012120) | 1.77622508 |
| 96 | Abnormality of the 1st metacarpal (HP:0010009) | 1.77044389 |
| 97 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.76764112 |
| 98 | Male pseudohermaphroditism (HP:0000037) | 1.76495792 |
| 99 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.76221479 |
| 100 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.75452137 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 5.70477878 |
| 2 | TLK1 | 4.57260260 |
| 3 | ADRBK2 | 3.21110493 |
| 4 | BMPR1B | 3.11860550 |
| 5 | GRK1 | 2.91476673 |
| 6 | TAOK3 | 2.87521256 |
| 7 | ZAK | 2.50902742 |
| 8 | ACVR1B | 2.41171094 |
| 9 | WNK4 | 2.22685088 |
| 10 | PINK1 | 2.11855769 |
| 11 | PHKG2 | 1.84993780 |
| 12 | PHKG1 | 1.84993780 |
| 13 | NUAK1 | 1.71168224 |
| 14 | INSRR | 1.66319772 |
| 15 | SGK2 | 1.59334757 |
| 16 | MAP4K2 | 1.56628956 |
| 17 | TXK | 1.52054035 |
| 18 | OXSR1 | 1.51279676 |
| 19 | WNK3 | 1.43294816 |
| 20 | MAPK13 | 1.37595574 |
| 21 | MAPKAPK3 | 1.33868271 |
| 22 | STK39 | 1.30706562 |
| 23 | SGK494 | 1.27364245 |
| 24 | SGK223 | 1.27364245 |
| 25 | STK16 | 1.27231146 |
| 26 | MAP3K4 | 1.20696090 |
| 27 | DAPK2 | 1.16053748 |
| 28 | TNIK | 1.14941542 |
| 29 | TAF1 | 1.13193715 |
| 30 | MST4 | 1.11660917 |
| 31 | ADRBK1 | 1.08343428 |
| 32 | CASK | 1.07780455 |
| 33 | PIK3CA | 1.06544942 |
| 34 | MAPK15 | 1.04628839 |
| 35 | TIE1 | 0.98289915 |
| 36 | MAP2K6 | 0.97796817 |
| 37 | PRKCG | 0.97583034 |
| 38 | AKT3 | 0.97259837 |
| 39 | MAPKAPK5 | 0.94135052 |
| 40 | IKBKB | 0.91173392 |
| 41 | PAK3 | 0.90666998 |
| 42 | NTRK3 | 0.90663426 |
| 43 | VRK1 | 0.89784205 |
| 44 | TEC | 0.83381228 |
| 45 | RPS6KA6 | 0.81361088 |
| 46 | PLK2 | 0.81123128 |
| 47 | STK11 | 0.78142989 |
| 48 | PRKCE | 0.77734438 |
| 49 | GRK7 | 0.75360711 |
| 50 | TRPM7 | 0.74900536 |
| 51 | SGK3 | 0.73641369 |
| 52 | OBSCN | 0.73614985 |
| 53 | GRK5 | 0.73392775 |
| 54 | NLK | 0.72186348 |
| 55 | PRKACA | 0.67661473 |
| 56 | NME1 | 0.65803918 |
| 57 | MAP2K7 | 0.65611210 |
| 58 | MKNK2 | 0.64610897 |
| 59 | SGK1 | 0.60716558 |
| 60 | PRKCI | 0.60409094 |
| 61 | PRKAA2 | 0.60374344 |
| 62 | CHUK | 0.59832093 |
| 63 | TGFBR1 | 0.59248269 |
| 64 | RPS6KA5 | 0.57813834 |
| 65 | MUSK | 0.57776643 |
| 66 | PKN1 | 0.57477747 |
| 67 | DYRK2 | 0.57437256 |
| 68 | PRKCQ | 0.55717202 |
| 69 | CSNK1G2 | 0.55573515 |
| 70 | RPS6KA2 | 0.54998553 |
| 71 | KIT | 0.54800447 |
| 72 | BLK | 0.54392115 |
| 73 | CAMK2A | 0.53494641 |
| 74 | PRKCH | 0.50652712 |
| 75 | MARK1 | 0.48475593 |
| 76 | PTK2B | 0.48135286 |
| 77 | CSNK1A1 | 0.48133661 |
| 78 | STK38L | 0.47987029 |
| 79 | SYK | 0.47694579 |
| 80 | CAMK1 | 0.47277258 |
| 81 | TNK2 | 0.45978582 |
| 82 | MAP3K9 | 0.43775915 |
| 83 | CAMKK2 | 0.42693942 |
| 84 | PLK4 | 0.42344080 |
| 85 | CSNK1G1 | 0.41571646 |
| 86 | MAP2K1 | 0.41217042 |
| 87 | PRKCA | 0.39898145 |
| 88 | WNK1 | 0.39633388 |
| 89 | PRKAA1 | 0.39119443 |
| 90 | MARK3 | 0.38960678 |
| 91 | RPS6KL1 | 0.38954787 |
| 92 | RPS6KC1 | 0.38954787 |
| 93 | CDK19 | 0.38673984 |
| 94 | MAP2K2 | 0.37651148 |
| 95 | PRKG1 | 0.37631006 |
| 96 | PNCK | 0.36822443 |
| 97 | CDK9 | 0.36593918 |
| 98 | FGFR2 | 0.36144861 |
| 99 | ITK | 0.35124900 |
| 100 | BCKDK | 0.34110587 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.51973049 |
| 2 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.37135504 |
| 3 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.36057183 |
| 4 | Phototransduction_Homo sapiens_hsa04744 | 2.26211154 |
| 5 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.26032127 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.25734449 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.20939481 |
| 8 | Nicotine addiction_Homo sapiens_hsa05033 | 2.13296943 |
| 9 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.98525020 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.97702189 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.90125314 |
| 12 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.88799002 |
| 13 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.88388672 |
| 14 | Protein export_Homo sapiens_hsa03060 | 1.71746478 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.70106210 |
| 16 | Basal transcription factors_Homo sapiens_hsa03022 | 1.59009640 |
| 17 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.58565463 |
| 18 | Parkinsons disease_Homo sapiens_hsa05012 | 1.58178392 |
| 19 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.54398442 |
| 20 | Morphine addiction_Homo sapiens_hsa05032 | 1.54203884 |
| 21 | RNA polymerase_Homo sapiens_hsa03020 | 1.52910749 |
| 22 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.48835829 |
| 23 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.48462321 |
| 24 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.48408553 |
| 25 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.45936203 |
| 26 | Retinol metabolism_Homo sapiens_hsa00830 | 1.44101913 |
| 27 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.40304823 |
| 28 | Insulin secretion_Homo sapiens_hsa04911 | 1.38684457 |
| 29 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.38395396 |
| 30 | Taste transduction_Homo sapiens_hsa04742 | 1.37783889 |
| 31 | Sulfur relay system_Homo sapiens_hsa04122 | 1.35088965 |
| 32 | Circadian entrainment_Homo sapiens_hsa04713 | 1.31442939 |
| 33 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.30171063 |
| 34 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.29538917 |
| 35 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.27124453 |
| 36 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.25277367 |
| 37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.23290046 |
| 38 | Alzheimers disease_Homo sapiens_hsa05010 | 1.23250036 |
| 39 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.22523662 |
| 40 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.21338484 |
| 41 | Asthma_Homo sapiens_hsa05310 | 1.20747440 |
| 42 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.19500653 |
| 43 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.17582181 |
| 44 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.16824942 |
| 45 | Ribosome_Homo sapiens_hsa03010 | 1.16467527 |
| 46 | Olfactory transduction_Homo sapiens_hsa04740 | 1.15447384 |
| 47 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.13436255 |
| 48 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.12607053 |
| 49 | Huntingtons disease_Homo sapiens_hsa05016 | 1.03917819 |
| 50 | GABAergic synapse_Homo sapiens_hsa04727 | 0.99918581 |
| 51 | RNA degradation_Homo sapiens_hsa03018 | 0.96432376 |
| 52 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.94043898 |
| 53 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.92915756 |
| 54 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.92094057 |
| 55 | ABC transporters_Homo sapiens_hsa02010 | 0.90435715 |
| 56 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.88120940 |
| 57 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.87774883 |
| 58 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.86838425 |
| 59 | Renin secretion_Homo sapiens_hsa04924 | 0.86565794 |
| 60 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.86313233 |
| 61 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.86166412 |
| 62 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.83795179 |
| 63 | Mineral absorption_Homo sapiens_hsa04978 | 0.81755459 |
| 64 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78658861 |
| 65 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.77814205 |
| 66 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.77067943 |
| 67 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.75287328 |
| 68 | Histidine metabolism_Homo sapiens_hsa00340 | 0.73242707 |
| 69 | Salivary secretion_Homo sapiens_hsa04970 | 0.72533818 |
| 70 | Peroxisome_Homo sapiens_hsa04146 | 0.72463866 |
| 71 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.72148827 |
| 72 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.71765059 |
| 73 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.70505159 |
| 74 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.70160739 |
| 75 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.70058663 |
| 76 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.69711482 |
| 77 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.68711897 |
| 78 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.67004833 |
| 79 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.66430801 |
| 80 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.65516620 |
| 81 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.64890589 |
| 82 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.63880996 |
| 83 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.63261771 |
| 84 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.62071261 |
| 85 | Allograft rejection_Homo sapiens_hsa05330 | 0.60820937 |
| 86 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.56328723 |
| 87 | Circadian rhythm_Homo sapiens_hsa04710 | 0.55146193 |
| 88 | Cocaine addiction_Homo sapiens_hsa05030 | 0.54673193 |
| 89 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.54123894 |
| 90 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.52611743 |
| 91 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.52207276 |
| 92 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.51745781 |
| 93 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.50395465 |
| 94 | Melanoma_Homo sapiens_hsa05218 | 0.50106899 |
| 95 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.48176027 |
| 96 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.46593986 |
| 97 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.45788070 |
| 98 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.45145184 |
| 99 | Purine metabolism_Homo sapiens_hsa00230 | 0.43949273 |
| 100 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.43513264 |

