ATG101

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)8.07073927
2proline biosynthetic process (GO:0006561)7.22990248
3transcription from mitochondrial promoter (GO:0006390)6.40392881
4COPI coating of Golgi vesicle (GO:0048205)5.59587693
5Golgi transport vesicle coating (GO:0048200)5.59587693
6proline metabolic process (GO:0006560)5.52775481
7replication fork processing (GO:0031297)5.48215408
8formation of translation preinitiation complex (GO:0001731)5.17101902
9maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)4.87631343
10telomere maintenance via semi-conservative replication (GO:0032201)4.84272813
11viral mRNA export from host cell nucleus (GO:0046784)4.82470128
12positive regulation of protein homooligomerization (GO:0032464)4.75909097
13embryonic process involved in female pregnancy (GO:0060136)4.71458124
14establishment of protein localization to mitochondrial membrane (GO:0090151)4.57448232
15protein maturation by protein folding (GO:0022417)4.52545473
16proteasome assembly (GO:0043248)4.49424898
17DNA strand elongation involved in DNA replication (GO:0006271)4.36482950
18somatic diversification of immune receptors via somatic mutation (GO:0002566)4.33249198
19somatic hypermutation of immunoglobulin genes (GO:0016446)4.33249198
20maintenance of protein localization in endoplasmic reticulum (GO:0035437)4.25275341
21mitochondrial DNA metabolic process (GO:0032042)4.25050083
22protein retention in ER lumen (GO:0006621)4.18273694
23DNA strand elongation (GO:0022616)4.12585467
24nucleotide-excision repair, DNA gap filling (GO:0006297)4.05074146
25regulation of protein homooligomerization (GO:0032462)4.04885715
26telomere maintenance via recombination (GO:0000722)4.04613005
27negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.99891752
28mitotic G1 DNA damage checkpoint (GO:0031571)3.95087806
29protein deneddylation (GO:0000338)3.88931203
30cullin deneddylation (GO:0010388)3.88126988
31nuclear envelope reassembly (GO:0031468)3.87898770
32mitotic nuclear envelope reassembly (GO:0007084)3.87898770
33oxidative demethylation (GO:0070989)3.83325285
34ribosome biogenesis (GO:0042254)3.80107384
35mitochondrial RNA metabolic process (GO:0000959)3.74075308
36ribosome assembly (GO:0042255)3.72883313
37poly(A)+ mRNA export from nucleus (GO:0016973)3.69842257
38maturation of 5.8S rRNA (GO:0000460)3.68048873
39pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.64268537
40pseudouridine synthesis (GO:0001522)3.62999929
41DNA integration (GO:0015074)3.62160755
42negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.59577556
43GDP-mannose metabolic process (GO:0019673)3.59251810
44DNA strand renaturation (GO:0000733)3.56725252
45UV protection (GO:0009650)3.54945045
46nucleobase-containing small molecule interconversion (GO:0015949)3.52637750
47mitotic G1/S transition checkpoint (GO:0044819)3.51299157
48regulation of retinoic acid receptor signaling pathway (GO:0048385)3.50475667
49telomere maintenance via telomere lengthening (GO:0010833)3.47887365
50regulation of double-strand break repair via homologous recombination (GO:0010569)3.45776741
51mitotic recombination (GO:0006312)3.44672595
52regulation of integrin activation (GO:0033623)3.43758473
53base-excision repair (GO:0006284)3.43152912
54rRNA processing (GO:0006364)3.38855159
55protein neddylation (GO:0045116)3.36867039
56non-recombinational repair (GO:0000726)3.32926272
57double-strand break repair via nonhomologous end joining (GO:0006303)3.32926272
58G1 DNA damage checkpoint (GO:0044783)3.31765834
59spliceosomal snRNP assembly (GO:0000387)3.31726217
60regulation of apoptotic process involved in morphogenesis (GO:1902337)3.29817166
61base-excision repair, AP site formation (GO:0006285)3.29131745
62termination of RNA polymerase II transcription (GO:0006369)3.28417444
63retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.27422126
64ribonucleoprotein complex biogenesis (GO:0022613)3.26528070
65histone arginine methylation (GO:0034969)3.24787529
66mRNA cleavage (GO:0006379)3.23988701
67DNA ligation (GO:0006266)3.23826672
68nucleobase biosynthetic process (GO:0046112)3.23709461
69mitochondrial fusion (GO:0008053)3.23306427
70rRNA metabolic process (GO:0016072)3.22799737
71maturation of SSU-rRNA (GO:0030490)3.22337812
72kinetochore assembly (GO:0051382)3.22202681
73barbed-end actin filament capping (GO:0051016)3.21715568
74negative regulation of mRNA processing (GO:0050686)3.19383315
75skin morphogenesis (GO:0043589)3.14724080
76purine nucleobase biosynthetic process (GO:0009113)3.12968028
77translational initiation (GO:0006413)3.11698630
78ribosomal small subunit assembly (GO:0000028)3.11405258
79establishment of apical/basal cell polarity (GO:0035089)3.10118732
80oxidative phosphorylation (GO:0006119)3.08611906
81mitochondrial DNA replication (GO:0006264)3.08097442
82negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.06568073
83transcription-coupled nucleotide-excision repair (GO:0006283)3.06373919
84protein complex localization (GO:0031503)3.06323868
85meiotic chromosome segregation (GO:0045132)3.06115287
86DNA replication checkpoint (GO:0000076)3.05785605
87nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.99077346
88establishment of viral latency (GO:0019043)2.99031966
89viral transcription (GO:0019083)2.98992190
90negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.98276191
91negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.97540463
92DNA double-strand break processing (GO:0000729)2.95410941
93negative regulation of RNA splicing (GO:0033119)2.93576996
94nucleotide-sugar biosynthetic process (GO:0009226)2.93299033
95negative regulation of fatty acid biosynthetic process (GO:0045717)2.92217669
96regulation of translational fidelity (GO:0006450)2.91305430
97protein targeting to mitochondrion (GO:0006626)2.91285068
98establishment of protein localization to mitochondrion (GO:0072655)2.90051777
99negative regulation of JAK-STAT cascade (GO:0046426)2.89171693
100regulation of cellular amino acid metabolic process (GO:0006521)2.88732857
101translational termination (GO:0006415)2.88040122
102cellular response to zinc ion (GO:0071294)2.88009382
103ribosomal small subunit biogenesis (GO:0042274)2.87790683
104anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.87166257
105rRNA modification (GO:0000154)2.86238507
106transcription elongation from RNA polymerase III promoter (GO:0006385)2.86222132
107termination of RNA polymerase III transcription (GO:0006386)2.86222132
108negative regulation of cell cycle arrest (GO:0071157)2.85845017
109DNA replication initiation (GO:0006270)2.85703118
110DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.83805667
111positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.83740387
112single strand break repair (GO:0000012)2.83236558
113pyrimidine nucleotide catabolic process (GO:0006244)2.83122734
114regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.81594192
115folic acid metabolic process (GO:0046655)2.80752621
116signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.79737807
117signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.79737807
118signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.79737807
119spliceosomal tri-snRNP complex assembly (GO:0000244)2.79634418
120negative regulation of ligase activity (GO:0051352)2.78991381
121negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.78991381
122cell cycle G1/S phase transition (GO:0044843)2.78678884
123G1/S transition of mitotic cell cycle (GO:0000082)2.78678884
124positive regulation of DNA repair (GO:0045739)2.78160382
125endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.77943968
126intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.77878842
127signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.77878842
128tRNA methylation (GO:0030488)2.77570067
129pentose-phosphate shunt (GO:0006098)2.77181754
130negative regulation of hydrogen peroxide-induced cell death (GO:1903206)2.76305186
131positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.76080028
132regulation of autophagic vacuole assembly (GO:2000785)2.73700169
133activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.72905606
134virion assembly (GO:0019068)2.72830825
135regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.70605568
136hyaluronan catabolic process (GO:0030214)2.64692959
137cellular response to arsenic-containing substance (GO:0071243)2.64142519
138positive regulation of nuclease activity (GO:0032075)2.62840045
139pyrimidine nucleoside salvage (GO:0043097)2.62764203
140pyrimidine-containing compound salvage (GO:0008655)2.62764203
141deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.62128741
142rRNA transcription (GO:0009303)2.60471198
143establishment of integrated proviral latency (GO:0075713)2.59836703
144monosaccharide biosynthetic process (GO:0046364)2.59288674
145regulation of translational termination (GO:0006449)2.59082279
146positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.58999035
147embryo implantation (GO:0007566)2.58823994
148regulation of vacuole organization (GO:0044088)2.58663528
149regulation of mammary gland epithelial cell proliferation (GO:0033599)2.57990754
150peptidyl-proline hydroxylation (GO:0019511)2.56624403
151actin filament depolymerization (GO:0030042)2.55076092
152protein localization to endosome (GO:0036010)2.54943181
153peptidyl-arginine omega-N-methylation (GO:0035247)2.54706750
1547-methylguanosine mRNA capping (GO:0006370)2.53995883
155endoplasmic reticulum unfolded protein response (GO:0030968)2.53560265
156cellular protein complex localization (GO:0034629)2.52451100
157NADPH regeneration (GO:0006740)2.51338544
158de novo protein folding (GO:0006458)2.51136646
159pinocytosis (GO:0006907)2.50485644
160negative regulation of response to reactive oxygen species (GO:1901032)2.49457167
161de novo posttranslational protein folding (GO:0051084)2.48238012
162activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.47581172
163positive regulation of ligase activity (GO:0051351)2.45922266
164lung vasculature development (GO:0060426)2.45136407
165regulation of ubiquitin-protein transferase activity (GO:0051438)2.45025161
166dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.43492739
167glucose catabolic process (GO:0006007)2.43060337
168negative regulation of cell size (GO:0045792)2.42935321
1697-methylguanosine RNA capping (GO:0009452)2.42598797
170RNA capping (GO:0036260)2.42598797
171regulation of oxidative stress-induced neuron death (GO:1903203)2.41701546
172negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902176)2.39612864
173hexose biosynthetic process (GO:0019319)2.38766281
174COPII vesicle coating (GO:0048208)2.38496506
175trophoblast giant cell differentiation (GO:0060707)2.37447989
176positive regulation of astrocyte differentiation (GO:0048711)2.36568876
177negative regulation of oxidative stress-induced cell death (GO:1903202)2.35872485
178regulation of nuclease activity (GO:0032069)2.35278510
179regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.34652090

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.04346343
2MYC_18555785_ChIP-Seq_MESCs_Mouse3.85668032
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.47986354
4JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.14943106
5TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.98457014
6MYC_18358816_ChIP-ChIP_MESCs_Mouse2.96533046
7ETS1_20019798_ChIP-Seq_JURKAT_Human2.79558988
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.78168617
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.63769513
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.54652456
11GABP_17652178_ChIP-ChIP_JURKAT_Human2.52864393
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.51505205
13RARG_19884340_ChIP-ChIP_MEFs_Mouse2.45469390
14SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.34783210
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.28450872
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.23540188
17E2F1_18555785_ChIP-Seq_MESCs_Mouse2.23412164
18TP63_17297297_ChIP-ChIP_HaCaT_Human2.16602417
19YY1_21170310_ChIP-Seq_MESCs_Mouse2.16337365
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.15212464
21FOXM1_23109430_ChIP-Seq_U2OS_Human2.14087779
22CREB1_15753290_ChIP-ChIP_HEK293T_Human2.13114617
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.08453030
24TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.08125175
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.04959610
26E2F4_17652178_ChIP-ChIP_JURKAT_Human2.03283068
27XRN2_22483619_ChIP-Seq_HELA_Human2.02079081
28KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.00338325
29KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.00338325
30KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.00338325
31THAP11_20581084_ChIP-Seq_MESCs_Mouse1.98572699
32POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.94873030
33DCP1A_22483619_ChIP-Seq_HELA_Human1.94485993
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.91391428
35STAT3_1855785_ChIP-Seq_MESCs_Mouse1.90663722
36ELK3_25401928_ChIP-Seq_HUVEC_Human1.90042075
37PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.88112485
38VDR_23849224_ChIP-Seq_CD4+_Human1.87912797
39GABP_19822575_ChIP-Seq_HepG2_Human1.87031074
40RACK7_27058665_Chip-Seq_MCF-7_Human1.86106405
41NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.83963947
42LXR_22292898_ChIP-Seq_THP-1_Human1.82370231
43POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.81247847
44KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.81183991
45ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.74842058
46DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.70975485
47VDR_21846776_ChIP-Seq_THP-1_Human1.70770325
48SRF_21415370_ChIP-Seq_HL-1_Mouse1.67988184
49TTF2_22483619_ChIP-Seq_HELA_Human1.66490432
50NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.65899627
51HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.64548082
52HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.63721547
53TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.62056341
54MYCN_18555785_ChIP-Seq_MESCs_Mouse1.60981273
55POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.60181883
56SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.58153091
57ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.58146805
58ATF3_27146783_Chip-Seq_COLON_Human1.53791206
59NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.52472524
60BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.51414384
61MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.51269811
62E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.49851377
63CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.49492831
64CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.46602146
65ESR2_21235772_ChIP-Seq_MCF-7_Human1.45632317
66FOXP3_21729870_ChIP-Seq_TREG_Human1.43910331
67TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.43553314
68SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.40360941
69KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.39621402
70KLF4_18555785_ChIP-Seq_MESCs_Mouse1.38148884
71KDM5A_27292631_Chip-Seq_BREAST_Human1.36398431
72ELF1_17652178_ChIP-ChIP_JURKAT_Human1.35799511
73PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.34782559
74ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.33747488
75HIF1A_21447827_ChIP-Seq_MCF-7_Human1.33744634
76NANOG_21062744_ChIP-ChIP_HESCs_Human1.33677341
77SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.33622174
78PU.1_20513432_ChIP-Seq_Bcells_Mouse1.30336373
79ZFX_18555785_ChIP-Seq_MESCs_Mouse1.30157124
80CLOCK_20551151_ChIP-Seq_293T_Human1.27663676
81TCF3_18692474_ChIP-Seq_MEFs_Mouse1.27058070
82CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.26770611
83NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.20879952
84TET1_21451524_ChIP-Seq_MESCs_Mouse1.20483303
85TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.20396627
86CTCF_18555785_ChIP-Seq_MESCs_Mouse1.20133332
87UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.19959382
88CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.19285190
89SOX2_18692474_ChIP-Seq_MEFs_Mouse1.18557424
90RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18139598
91FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.17904212
92CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.17071750
93MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.16957365
94CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.16569733
95RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.15914809
96OCT4_18692474_ChIP-Seq_MEFs_Mouse1.15450400
97PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15178040
98MYC_22102868_ChIP-Seq_BL_Human1.14994536
99SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.14478528
100NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.14060741
101SOX2_18555785_ChIP-Seq_MESCs_Mouse1.14011378
102E2F1_21310950_ChIP-Seq_MCF-7_Human1.13530926
103CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.12661276
104SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.12610700
105TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.12494197
106TCF3_18692474_ChIP-Seq_MESCs_Mouse1.12119885
107P68_20966046_ChIP-Seq_HELA_Human1.11062018
108TP53_22127205_ChIP-Seq_IMR90_Human1.10472302
109MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.09992806
110SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.09980066
111KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.09697914
112SA1_27219007_Chip-Seq_ERYTHROID_Human1.09621499
113SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.09411951
114ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.09400950
115FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.09043417
116TBX5_21415370_ChIP-Seq_HL-1_Mouse1.08943423
117THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.08814095
118POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.08807909
119POU5F1_16518401_ChIP-PET_MESCs_Mouse1.08711578
120TFEB_21752829_ChIP-Seq_HELA_Human1.07980547
121FOXP1_21924763_ChIP-Seq_HESCs_Human1.07305239
122ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.07073038
123KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.06717455
124ELF1_20517297_ChIP-Seq_JURKAT_Human1.05878952
125SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.04999944
126TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.04441642
127PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03686382
128SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.03667520
129ZNF263_19887448_ChIP-Seq_K562_Human1.03255319
130SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.02866177
131SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.02772861
132SRY_22984422_ChIP-ChIP_TESTIS_Rat1.02472625
133ELK1_19687146_ChIP-ChIP_HELA_Human1.02044508
134CTCF_27219007_Chip-Seq_ERYTHROID_Human1.00995819
135P300_27058665_Chip-Seq_ZR-75-30cells_Human1.00957582
136KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.00903943
137NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.00661006
138ESR1_21235772_ChIP-Seq_MCF-7_Human0.99688145
139SMC4_20622854_ChIP-Seq_HELA_Human0.98902331
140YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.98339800
141HOXB4_20404135_ChIP-ChIP_EML_Mouse0.98254591
142CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.97019687
143YY1_22570637_ChIP-Seq_MALME-3M_Human0.93094829
144NOTCH1_21737748_ChIP-Seq_TLL_Human0.92845363

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.89516190
2MP0009840_abnormal_foam_cell4.40759027
3MP0003693_abnormal_embryo_hatching3.86921015
4MP0005451_abnormal_body_composition3.62536109
5MP0010094_abnormal_chromosome_stability3.53927453
6MP0004957_abnormal_blastocyst_morpholog3.49191745
7MP0008438_abnormal_cutaneous_collagen3.05195510
8MP0009278_abnormal_bone_marrow3.03457786
9MP0003111_abnormal_nucleus_morphology2.85647554
10MP0003705_abnormal_hypodermis_morpholog2.85427060
11MP0010234_abnormal_vibrissa_follicle2.82120716
12MP0008058_abnormal_DNA_repair2.68183730
13MP0003077_abnormal_cell_cycle2.65832645
14MP0003786_premature_aging2.65744495
15MP0010030_abnormal_orbit_morphology2.64021502
16MP0003806_abnormal_nucleotide_metabolis2.62164073
17MP0005171_absent_coat_pigmentation2.55164915
18MP0004272_abnormal_basement_membrane2.50916428
19MP0005397_hematopoietic_system_phenotyp2.34863668
20MP0001545_abnormal_hematopoietic_system2.34863668
21MP0008932_abnormal_embryonic_tissue2.32508758
22MP0003718_maternal_effect2.31078544
23MP0010352_gastrointestinal_tract_polyps2.28042378
24MP0001849_ear_inflammation2.23960070
25MP0003566_abnormal_cell_adhesion2.14416309
26MP0005075_abnormal_melanosome_morpholog2.07557238
27MP0008995_early_reproductive_senescence2.04542149
28MP0000490_abnormal_crypts_of2.03763280
29MP0005623_abnormal_meninges_morphology2.02895505
30MP0008877_abnormal_DNA_methylation1.95578809
31MP0000749_muscle_degeneration1.91427762
32MP0005257_abnormal_intraocular_pressure1.90131748
33MP0004133_heterotaxia1.76154823
34MP0002877_abnormal_melanocyte_morpholog1.76146957
35MP0003186_abnormal_redox_activity1.70558125
36MP0000750_abnormal_muscle_regeneration1.65273032
37MP0003567_abnormal_fetal_cardiomyocyte1.63653495
38MP0005085_abnormal_gallbladder_physiolo1.60565644
39MP0003656_abnormal_erythrocyte_physiolo1.60227099
40MP0000537_abnormal_urethra_morphology1.59813892
41MP0003941_abnormal_skin_development1.57862261
42MP0001730_embryonic_growth_arrest1.57428866
43MP0002060_abnormal_skin_morphology1.55420587
44MP0000350_abnormal_cell_proliferation1.55330568
45MP0005174_abnormal_tail_pigmentation1.54941475
46MP0003950_abnormal_plasma_membrane1.54079781
47MP0005409_darkened_coat_color1.50988986
48MP0001697_abnormal_embryo_size1.48309709
49MP0006036_abnormal_mitochondrial_physio1.47165631
50MP0003890_abnormal_embryonic-extraembry1.46994869
51MP0002019_abnormal_tumor_incidence1.46755505
52MP0001727_abnormal_embryo_implantation1.46098152
53MP0009333_abnormal_splenocyte_physiolog1.43773464
54MP0000343_altered_response_to1.43500789
55MP0005023_abnormal_wound_healing1.42754656
56MP0004233_abnormal_muscle_weight1.40639425
57MP0002086_abnormal_extraembryonic_tissu1.38232326
58MP0002009_preneoplasia1.37946634
59MP0002254_reproductive_system_inflammat1.37453925
60MP0002396_abnormal_hematopoietic_system1.37345113
61MP0001542_abnormal_bone_strength1.37015037
62MP0000747_muscle_weakness1.35321403
63MP0003453_abnormal_keratinocyte_physiol1.34100475
64MP0002653_abnormal_ependyma_morphology1.31645996
65MP0001672_abnormal_embryogenesis/_devel1.31053235
66MP0005380_embryogenesis_phenotype1.31053235
67MP0002796_impaired_skin_barrier1.30462910
68MP0001764_abnormal_homeostasis1.29247992
69MP0000015_abnormal_ear_pigmentation1.28362134
70MP0002132_abnormal_respiratory_system1.27440175
71MP0005266_abnormal_metabolism1.26987964
72MP0001216_abnormal_epidermal_layer1.25001017
73MP0008007_abnormal_cellular_replicative1.23576917
74MP0002085_abnormal_embryonic_tissue1.21437898
75MP0002080_prenatal_lethality1.20813205
76MP0002089_abnormal_postnatal_growth/wei1.17854187
77MP0002084_abnormal_developmental_patter1.16637553
78MP0003119_abnormal_digestive_system1.16351948
79MP0000313_abnormal_cell_death1.16060191
80MP0005083_abnormal_biliary_tract1.15864880
81MP0003191_abnormal_cellular_cholesterol1.14832058
82MP0000858_altered_metastatic_potential1.14644576
83MP0000762_abnormal_tongue_morphology1.14271634
84MP0004197_abnormal_fetal_growth/weight/1.12926185
85MP0000751_myopathy1.11932447
86MP0005365_abnormal_bile_salt1.11191121
87MP0001881_abnormal_mammary_gland1.11006240
88MP0004858_abnormal_nervous_system1.10529364
89MP0004019_abnormal_vitamin_homeostasis1.09721199
90MP0002282_abnormal_trachea_morphology1.09255942
91MP0002249_abnormal_larynx_morphology1.08969865
92MP0000627_abnormal_mammary_gland1.08915688
93MP0000678_abnormal_parathyroid_gland1.06916979
94MP0003984_embryonic_growth_retardation1.06571936
95MP0000759_abnormal_skeletal_muscle1.04024481
96MP0000689_abnormal_spleen_morphology1.03880011
97MP0002098_abnormal_vibrissa_morphology1.02701486
98MP0001661_extended_life_span1.02570349
99MP0010771_integument_phenotype1.01515124
100MP0005410_abnormal_fertilization1.00784916
101MP0002088_abnormal_embryonic_growth/wei1.00699354
102MP0000371_diluted_coat_color1.00112113
103MP0000470_abnormal_stomach_morphology0.99099505
104MP0001243_abnormal_dermal_layer0.98843444
105MP0005501_abnormal_skin_physiology0.98574544
106MP0006292_abnormal_olfactory_placode0.95108896
107MP0004510_myositis0.94752271
108MP0002269_muscular_atrophy0.93976293
109MP0005330_cardiomyopathy0.93339330
110MP0003091_abnormal_cell_migration0.91612047
111MP0005376_homeostasis/metabolism_phenot0.90981772
112MP0000733_abnormal_muscle_development0.90706639
113MP0001145_abnormal_male_reproductive0.90501969
114MP0003300_gastrointestinal_ulcer0.90308713
115MP0004264_abnormal_extraembryonic_tissu0.89520175
116MP0000579_abnormal_nail_morphology0.88705814
117MP0002405_respiratory_system_inflammati0.88679455
118MP0000685_abnormal_immune_system0.87556207
119MP0003279_aneurysm0.86019183
120MP0001293_anophthalmia0.85388350
121MP0005395_other_phenotype0.83936981
122MP0002210_abnormal_sex_determination0.83506500
123MP0002111_abnormal_tail_morphology0.82531794
124MP0004185_abnormal_adipocyte_glucose0.81781572
125MP0004381_abnormal_hair_follicle0.81769292
126MP0005508_abnormal_skeleton_morphology0.81415315
127MP0002722_abnormal_immune_system0.81406789
128MP0005621_abnormal_cell_physiology0.80323119
129MP0003136_yellow_coat_color0.80048636
130MP0000467_abnormal_esophagus_morphology0.78769709
131MP0005384_cellular_phenotype0.77710819
132MP0006035_abnormal_mitochondrial_morpho0.77648467
133MP0000003_abnormal_adipose_tissue0.77602622
134MP0008260_abnormal_autophagy0.77557190
135MP0001188_hyperpigmentation0.77328252
136MP0001529_abnormal_vocalization0.77053430
137MP0010307_abnormal_tumor_latency0.74982002
138MP0005275_abnormal_skin_tensile0.74642091
139MP0009931_abnormal_skin_appearance0.74236360
140MP0004808_abnormal_hematopoietic_stem0.73615256
141MP0000653_abnormal_sex_gland0.73375718
142MP0002398_abnormal_bone_marrow0.73267585
143MP0003283_abnormal_digestive_organ0.71939711
144MP0000639_abnormal_adrenal_gland0.71535904
145MP0005332_abnormal_amino_acid0.71152261
146MP0000358_abnormal_cell_content/0.70678935
147MP0009250_abnormal_appendicular_skeleto0.70601131
148MP0000462_abnormal_digestive_system0.70277715
149MP0001853_heart_inflammation0.68666237
150MP0000598_abnormal_liver_morphology0.67233710
151MP0008004_abnormal_stomach_pH0.66618873
152MP0001119_abnormal_female_reproductive0.65975799
153MP0001929_abnormal_gametogenesis0.65601298
154MP0005058_abnormal_lysosome_morphology0.65118392
155MP0002295_abnormal_pulmonary_circulatio0.64729438
156MP0005076_abnormal_cell_differentiation0.63015172
157MP0005319_abnormal_enzyme/_coenzyme0.62963241
158MP0000477_abnormal_intestine_morphology0.61994847
159MP0003315_abnormal_perineum_morphology0.61950864
160MP0005394_taste/olfaction_phenotype0.61749848
161MP0005499_abnormal_olfactory_system0.61749848
162MP0003221_abnormal_cardiomyocyte_apopto0.60534953
163MP0002429_abnormal_blood_cell0.60219906
164MP0003942_abnormal_urinary_system0.60207429
165MP0001186_pigmentation_phenotype0.59981060
166MP0008873_increased_physiological_sensi0.59844328
167MP0003699_abnormal_female_reproductive0.58195917

Predicted human phenotypes

RankGene SetZ-score
1Pustule (HP:0200039)4.51610056
2Premature rupture of membranes (HP:0001788)4.20391666
3Concave nail (HP:0001598)4.15194411
4Rib fusion (HP:0000902)4.12238745
5Breast hypoplasia (HP:0003187)4.09904558
6Annular pancreas (HP:0001734)3.77563044
7Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.76167396
8Rectal fistula (HP:0100590)3.72769401
9Rectovaginal fistula (HP:0000143)3.72769401
10Poikiloderma (HP:0001029)3.69129530
11Facial hemangioma (HP:0000329)3.65365651
12Tongue fasciculations (HP:0001308)3.64054998
13Vertebral compression fractures (HP:0002953)3.62820396
14Patellar aplasia (HP:0006443)3.54831457
15Increased IgM level (HP:0003496)3.52562818
16Achilles tendon contracture (HP:0001771)3.44771278
17Vaginal fistula (HP:0004320)3.35614793
18Aplasia/Hypoplasia of the patella (HP:0006498)3.32636289
19Birth length less than 3rd percentile (HP:0003561)3.31985482
20Dysautonomia (HP:0002459)3.28032092
21Muscle fibrillation (HP:0010546)3.24032031
22Absent radius (HP:0003974)3.23794431
23Cerebral hypomyelination (HP:0006808)3.20351223
24Aplasia/hypoplasia of the humerus (HP:0006507)3.16639416
25Alopecia of scalp (HP:0002293)3.16005292
26Absent thumb (HP:0009777)3.11806300
27Intestinal fistula (HP:0100819)3.06805850
28Short nail (HP:0001799)3.05499486
29Abnormality of the Achilles tendon (HP:0005109)3.05014274
30Reduced antithrombin III activity (HP:0001976)3.02335595
31Absent forearm bone (HP:0003953)3.00029529
32Aplasia involving forearm bones (HP:0009822)3.00029529
33Hypochromic microcytic anemia (HP:0004840)2.99259008
34Spinal rigidity (HP:0003306)2.97523856
35Generalized amyotrophy (HP:0003700)2.96621506
36Exertional dyspnea (HP:0002875)2.95600405
37Orthostatic hypotension (HP:0001278)2.83965629
38Premature graying of hair (HP:0002216)2.80886866
39Protrusio acetabuli (HP:0003179)2.79608791
40Short humerus (HP:0005792)2.79212398
41Abnormal hemoglobin (HP:0011902)2.78251915
42Trismus (HP:0000211)2.76114850
43Vertebral hypoplasia (HP:0008417)2.76087389
44Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.76087389
45Abnormality of cells of the erythroid lineage (HP:0012130)2.75393565
46Centrally nucleated skeletal muscle fibers (HP:0003687)2.75197823
47Abnormal number of erythroid precursors (HP:0012131)2.74270002
48Abnormality of the umbilical cord (HP:0010881)2.70973487
49Abnormality of male internal genitalia (HP:0000022)2.70097459
50Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.69815225
51Decreased activity of mitochondrial respiratory chain (HP:0008972)2.69815225
52Distal lower limb muscle weakness (HP:0009053)2.69366740
53Muscle fiber atrophy (HP:0100295)2.67992864
54Type 2 muscle fiber atrophy (HP:0003554)2.64162757
55Abnormality of glycolipid metabolism (HP:0010969)2.62971017
56Abnormality of liposaccharide metabolism (HP:0010968)2.62971017
57Abnormality of glycosphingolipid metabolism (HP:0004343)2.62971017
58Elbow flexion contracture (HP:0002987)2.62454835
59Squamous cell carcinoma (HP:0002860)2.60479339
60Selective tooth agenesis (HP:0001592)2.59776130
61Distal upper limb amyotrophy (HP:0007149)2.59279406
62Upper limb amyotrophy (HP:0009129)2.59279406
63Abnormality of the aortic arch (HP:0012303)2.52184617
64Hyperacusis (HP:0010780)2.49605039
65Albinism (HP:0001022)2.49318271
66Aplasia/Hypoplasia involving the musculature (HP:0001460)2.47357392
67Abnormality of the labia minora (HP:0012880)2.45529052
68Entropion (HP:0000621)2.39515607
69Rough bone trabeculation (HP:0100670)2.39206008
70Premature ovarian failure (HP:0008209)2.38765065
71Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.38650313
72Male infertility (HP:0003251)2.38403466
73Hypokinesia (HP:0002375)2.37691565
74Basal cell carcinoma (HP:0002671)2.36264788
75Abnormality of dentin (HP:0010299)2.36071135
76Abnormal trabecular bone morphology (HP:0100671)2.35502791
77Broad alveolar ridges (HP:0000187)2.34879627
78Hepatocellular necrosis (HP:0001404)2.34358014
79Amniotic constriction ring (HP:0009775)2.33983662
80Abnormality of placental membranes (HP:0011409)2.33983662
81Aplasia/Hypoplasia of the sacrum (HP:0008517)2.33975835
82Reticulocytopenia (HP:0001896)2.30670883
83Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.30552491
84Intestinal atresia (HP:0011100)2.26291476
85Difficulty climbing stairs (HP:0003551)2.25720263
86Abnormality of the distal phalanges of the toes (HP:0010182)2.25538208
87Capillary hemangiomas (HP:0005306)2.24383055
88Abnormality of pyrimidine metabolism (HP:0004353)2.23988948
89Long palpebral fissure (HP:0000637)2.23781357
90Cholecystitis (HP:0001082)2.23263014
91Abnormal gallbladder physiology (HP:0012438)2.23263014
92CNS demyelination (HP:0007305)2.22610591
93Mitral stenosis (HP:0001718)2.21888893
94Oral leukoplakia (HP:0002745)2.21053738
95Abnormality of the anterior horn cell (HP:0006802)2.20886469
96Degeneration of anterior horn cells (HP:0002398)2.20886469
97Microretrognathia (HP:0000308)2.19541478
98Abnormality of the ileum (HP:0001549)2.18854816
99Hepatic necrosis (HP:0002605)2.17952558
100Distal lower limb amyotrophy (HP:0008944)2.17244025
101Abnormalities of placenta or umbilical cord (HP:0001194)2.16338142
102Axonal loss (HP:0003447)2.15510282
103Hypobetalipoproteinemia (HP:0003563)2.15477794
104Ragged-red muscle fibers (HP:0003200)2.15375172
105Limb-girdle muscle atrophy (HP:0003797)2.15105838
106Upper limb muscle weakness (HP:0003484)2.14828654
107Nonimmune hydrops fetalis (HP:0001790)2.11209232
108Increased serum lactate (HP:0002151)2.09883257
109Bulbar palsy (HP:0001283)2.08975540
110Hypochromic anemia (HP:0001931)2.08333705
111Hypoplasia of the radius (HP:0002984)2.07943155
112Ureteral duplication (HP:0000073)2.06818186
113Ankle contracture (HP:0006466)2.05604822
114Sensory axonal neuropathy (HP:0003390)2.05019765
115Type I transferrin isoform profile (HP:0003642)2.04782766
116Sparse eyelashes (HP:0000653)2.03096131
117Hand muscle atrophy (HP:0009130)2.02884334
118Aplasia of the musculature (HP:0100854)2.02774138
119Flattened epiphyses (HP:0003071)2.01758026
120Joint stiffness (HP:0001387)2.01462231
121Testicular atrophy (HP:0000029)2.00587918
122Carpal bone hypoplasia (HP:0001498)1.99666064
123Congenital glaucoma (HP:0001087)1.99616835
124Myopathic facies (HP:0002058)1.99245620
125Emotional lability (HP:0000712)1.99117473
126Sparse lateral eyebrow (HP:0005338)1.98770198
127Mildly elevated creatine phosphokinase (HP:0008180)1.96029155
128Redundant skin (HP:0001582)1.94295881
129Genu recurvatum (HP:0002816)1.94091961
130Abnormality of carpal bone ossification (HP:0006257)1.94083522
131Fragile skin (HP:0001030)1.93966057
132Increased connective tissue (HP:0009025)1.92176619
133Microvesicular hepatic steatosis (HP:0001414)1.91984915
134Ulnar bowing (HP:0003031)1.91111722
135Hypoplasia of the capital femoral epiphysis (HP:0003090)1.90870980
136Shoulder girdle muscle weakness (HP:0003547)1.90803993
137Agnosia (HP:0010524)1.89157523
138Atrophic scars (HP:0001075)1.88898105
139Progressive muscle weakness (HP:0003323)1.88112707
140Seborrheic dermatitis (HP:0001051)1.84296502
141Shawl scrotum (HP:0000049)1.84080724
142Abnormality of the fetal cardiovascular system (HP:0010948)1.83482276
143Abnormal umbilical cord blood vessels (HP:0011403)1.83482276
144Single umbilical artery (HP:0001195)1.83482276
145Mitral regurgitation (HP:0001653)1.83340801
146Abnormal autonomic nervous system physiology (HP:0012332)1.83043713
147Fatigue (HP:0012378)1.82982952
148Mitochondrial inheritance (HP:0001427)1.82719935
149Delusions (HP:0000746)1.82687838
150Blue sclerae (HP:0000592)1.82530511
151Abnormal protein glycosylation (HP:0012346)1.82183104
152Abnormal glycosylation (HP:0012345)1.82183104
153Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.82183104
154Abnormal protein N-linked glycosylation (HP:0012347)1.82183104
155Acute lymphatic leukemia (HP:0006721)1.81842354
156Diaphragmatic weakness (HP:0009113)1.81391857
157Bifid uvula (HP:0000193)1.81338154
158Hypotrichosis (HP:0001006)1.80935158
159Osteolytic defects of the phalanges of the hand (HP:0009771)1.80626297
160Osteolytic defects of the hand bones (HP:0009699)1.80626297
161Resting tremor (HP:0002322)1.80155461
162Insomnia (HP:0100785)1.79898330
163Rhabdomyolysis (HP:0003201)1.79230227
164Congenital hip dislocation (HP:0001374)1.78586263
165Turricephaly (HP:0000262)1.77752038
166Pterygium (HP:0001059)1.77434592
167Overriding aorta (HP:0002623)1.77025392
168Increased CSF lactate (HP:0002490)1.76996331
169Secondary amenorrhea (HP:0000869)1.74956144
170Opisthotonus (HP:0002179)1.74619830
171Congenital ichthyosiform erythroderma (HP:0007431)1.74558491
172Patellar dislocation (HP:0002999)1.74215104
173Scapular winging (HP:0003691)1.73737715
174J-shaped sella turcica (HP:0002680)1.73470683
175Short chin (HP:0000331)1.72973189
176Right ventricular cardiomyopathy (HP:0011663)1.72602484
177Small epiphyses (HP:0010585)1.71466518
178Lower limb hyperreflexia (HP:0002395)1.70409444
179Premature skin wrinkling (HP:0100678)1.70344925
180Lethargy (HP:0001254)1.70091006
181Short thumb (HP:0009778)1.69612960
182Neoplasm of head and neck (HP:0012288)1.69170029
183Esophageal neoplasm (HP:0100751)1.69170029
184Impulsivity (HP:0100710)1.69126170
185Increased variability in muscle fiber diameter (HP:0003557)1.68532854
186Chromosomal breakage induced by crosslinking agents (HP:0003221)1.67814926
187Wormian bones (HP:0002645)1.67292110

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.60865766
2MAP3K63.53386594
3ICK3.46712193
4PIM23.33243780
5MAP3K113.24038864
6MAPK153.22221581
7PINK13.16067243
8WEE13.13584084
9TRIB33.09807863
10DDR23.03990604
11TESK12.80370878
12VRK22.61272838
13DAPK12.50652895
14MATK2.50385344
15LMTK22.44055501
16NME22.29967914
17SMG12.13177834
18CDK71.96993839
19PBK1.93479575
20DYRK31.93205990
21FGR1.87069873
22ILK1.86417612
23AKT31.83392354
24PLK11.71711669
25YES11.65038207
26MST1R1.62117690
27ERN11.61473265
28MYLK1.58558575
29PIM11.58390289
30PLK41.57868710
31EPHA21.57123087
32SIK11.53592163
33UHMK11.52224143
34EIF2AK11.46618320
35TYRO31.41757124
36MAP3K121.41601129
37BRSK21.41593815
38MUSK1.38824246
39PKN21.36650859
40MAP3K31.33869516
41NEK11.30906114
42TESK21.26080026
43LIMK11.24286213
44CSK1.24249449
45TSSK61.21834834
46MARK31.20787073
47LATS21.20566128
48RPS6KC11.18621481
49RPS6KL11.18621481
50ARAF1.18309686
51MAP2K71.16133712
52VRK11.16044136
53CHEK21.15883788
54BCKDK1.14264430
55ACVR1B1.13074243
56PRKD21.08492589
57RPS6KA61.08347715
58DYRK1B1.08154349
59STK161.06939516
60RPS6KB21.04542224
61MAP3K91.03523452
62RAF11.01666761
63CDC71.01664226
64PDK20.99841128
65DYRK20.99676819
66TTK0.99651056
67BMX0.99228123
68TTN0.93095890
69DAPK30.92142185
70AURKA0.90910620
71TRPM70.90076976
72CSF1R0.88352381
73MAP3K10.88063337
74EIF2AK30.87995288
75BRSK10.86973485
76PTK20.86613414
77SRPK10.86430042
78PRKG20.84642291
79CDK60.81239319
80NEK20.80719108
81ZAK0.79085509
82ATR0.78948880
83AURKB0.77709861
84TLK10.75689938
85CSNK2A10.74420674
86LRRK20.73575774
87STK380.73054029
88SIK30.72350464
89MAPKAPK30.71867684
90CSNK1G30.71825044
91MOS0.70714196
92TBK10.69979712
93EEF2K0.69773193
94NME10.69213223
95TAOK20.68982454
96AKT20.67765386
97TAOK10.67699750
98MAPK110.67104089
99STK100.66806946
100KDR0.66528149
101ABL20.65873908
102PLK30.64631935
103CDK90.63182593
104MTOR0.62253401
105CSNK1A1L0.60270087
106RPS6KA40.59462765
107GRK60.58749050
108ERBB40.57919790
109CSNK2A20.57193696
110PRKCI0.56046416
111IRAK30.54098042
112CCNB10.53469964
113MET0.53307434
114CDK80.52448718
115STK30.52263818
116RPS6KA20.51477480
117RPS6KA10.50895649
118BMPR20.50367602
119PDPK10.50040136
120PRPF4B0.49981724
121PAK10.49618450
122MAP2K30.49027199
123MAP3K80.48710770
124CDK120.48254352
125CDK20.47165489
126PAK40.46902130
127RPS6KA50.46597593
128PAK20.45843668
129IRAK20.45670394
130BRAF0.45513679
131CDK140.45290942
132GSK3A0.45252864
133CSNK1G10.45094836
134FLT30.44082508
135STK240.43913693
136IKBKB0.43233165
137CAMK2B0.42481393
138MAPK40.42230853
139LYN0.36276129
140ERBB30.35800267
141EPHB10.35498624
142MST40.34644203
143CAMK2G0.33944343
144PDGFRA0.33937580
145CHEK10.33881766
146DMPK0.33832142
147MAP4K10.31907876
148CDK40.31099649
149MKNK20.29945682
150MAPKAPK20.28997177
151RPS6KB10.27851500

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034304.57716691
2DNA replication_Homo sapiens_hsa030304.53587777
3Base excision repair_Homo sapiens_hsa034103.99074570
4Proteasome_Homo sapiens_hsa030503.63218503
5Ribosome_Homo sapiens_hsa030103.40670158
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.37725859
7RNA polymerase_Homo sapiens_hsa030203.04574814
8Nucleotide excision repair_Homo sapiens_hsa034202.79508820
9Spliceosome_Homo sapiens_hsa030402.76159654
10Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.56921189
11Homologous recombination_Homo sapiens_hsa034402.44799473
12RNA transport_Homo sapiens_hsa030132.43569230
13Pyrimidine metabolism_Homo sapiens_hsa002402.08397859
14Sulfur relay system_Homo sapiens_hsa041221.97714967
15Folate biosynthesis_Homo sapiens_hsa007901.96540042
16Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.95947333
17Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.84499828
18Vibrio cholerae infection_Homo sapiens_hsa051101.83502894
19Other glycan degradation_Homo sapiens_hsa005111.74922397
20Fanconi anemia pathway_Homo sapiens_hsa034601.74461591
21Fatty acid biosynthesis_Homo sapiens_hsa000611.74413186
22Cell cycle_Homo sapiens_hsa041101.73681304
23N-Glycan biosynthesis_Homo sapiens_hsa005101.71329165
24Biosynthesis of amino acids_Homo sapiens_hsa012301.70156389
25One carbon pool by folate_Homo sapiens_hsa006701.49954175
262-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.49518519
27Oxidative phosphorylation_Homo sapiens_hsa001901.49005229
28p53 signaling pathway_Homo sapiens_hsa041151.47886378
29Parkinsons disease_Homo sapiens_hsa050121.38250618
30Fructose and mannose metabolism_Homo sapiens_hsa000511.34182260
31Central carbon metabolism in cancer_Homo sapiens_hsa052301.24329206
32Basal transcription factors_Homo sapiens_hsa030221.23434405
33RNA degradation_Homo sapiens_hsa030181.19988632
34Huntingtons disease_Homo sapiens_hsa050161.19409254
35Pentose and glucuronate interconversions_Homo sapiens_hsa000401.18592030
36Glycosaminoglycan degradation_Homo sapiens_hsa005311.18385568
37Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.17154637
38Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.15788578
39Arginine and proline metabolism_Homo sapiens_hsa003301.15425388
40Lysosome_Homo sapiens_hsa041421.13903282
41Pentose phosphate pathway_Homo sapiens_hsa000301.12280785
42Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.08639043
43Cysteine and methionine metabolism_Homo sapiens_hsa002701.07813029
44mRNA surveillance pathway_Homo sapiens_hsa030151.06169178
45Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.05911554
46Glutathione metabolism_Homo sapiens_hsa004801.03507181
47Drug metabolism - other enzymes_Homo sapiens_hsa009831.02405050
48Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.00507175
49Vitamin B6 metabolism_Homo sapiens_hsa007500.98977175
50Sulfur metabolism_Homo sapiens_hsa009200.97578162
51Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.92763118
52Cyanoamino acid metabolism_Homo sapiens_hsa004600.89354483
53Purine metabolism_Homo sapiens_hsa002300.89020616
54Non-homologous end-joining_Homo sapiens_hsa034500.84450484
55Epstein-Barr virus infection_Homo sapiens_hsa051690.83964646
56Galactose metabolism_Homo sapiens_hsa000520.81980812
57Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.80342574
58Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.78497524
59Prion diseases_Homo sapiens_hsa050200.78236423
60Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.76986032
61Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.76253438
62Salmonella infection_Homo sapiens_hsa051320.75117859
63Carbon metabolism_Homo sapiens_hsa012000.74750179
64Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73073509
65Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.72924416
66Hepatitis C_Homo sapiens_hsa051600.72117899
67Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.71532449
68Circadian rhythm_Homo sapiens_hsa047100.70205521
69Shigellosis_Homo sapiens_hsa051310.66126096
70Alzheimers disease_Homo sapiens_hsa050100.65693681
71Oocyte meiosis_Homo sapiens_hsa041140.63508680
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63042682
73Metabolic pathways_Homo sapiens_hsa011000.57690784
74Sphingolipid metabolism_Homo sapiens_hsa006000.56997058
75Primary immunodeficiency_Homo sapiens_hsa053400.55462311
76Tight junction_Homo sapiens_hsa045300.55461924
77Small cell lung cancer_Homo sapiens_hsa052220.55436115
78Notch signaling pathway_Homo sapiens_hsa043300.54378941
79SNARE interactions in vesicular transport_Homo sapiens_hsa041300.52794482
80Endocytosis_Homo sapiens_hsa041440.52142570
81Fatty acid metabolism_Homo sapiens_hsa012120.51801090
82Hippo signaling pathway_Homo sapiens_hsa043900.51649091
83Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.51084206
84Regulation of autophagy_Homo sapiens_hsa041400.50080531
85TNF signaling pathway_Homo sapiens_hsa046680.50042739
86Hepatitis B_Homo sapiens_hsa051610.49577062
87Bladder cancer_Homo sapiens_hsa052190.48788534
88Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.48521344
89mTOR signaling pathway_Homo sapiens_hsa041500.47911366
90Chronic myeloid leukemia_Homo sapiens_hsa052200.47564420
91Proteoglycans in cancer_Homo sapiens_hsa052050.46330584
92Focal adhesion_Homo sapiens_hsa045100.45629345
93Legionellosis_Homo sapiens_hsa051340.45118308
94Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44859819
95Thyroid cancer_Homo sapiens_hsa052160.44707978
96Transcriptional misregulation in cancer_Homo sapiens_hsa052020.44212989
97Arginine biosynthesis_Homo sapiens_hsa002200.43740225
98Phagosome_Homo sapiens_hsa041450.43427741
99Endometrial cancer_Homo sapiens_hsa052130.41482034
100AMPK signaling pathway_Homo sapiens_hsa041520.40977436
101Prostate cancer_Homo sapiens_hsa052150.40876601
102Steroid biosynthesis_Homo sapiens_hsa001000.40621882
103Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.40321567
104Alcoholism_Homo sapiens_hsa050340.39833528
105Fatty acid elongation_Homo sapiens_hsa000620.37729678
106Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.37156297
107Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.37141824
108Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.36863829
109Selenocompound metabolism_Homo sapiens_hsa004500.36758389
110Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.35981609
111Arachidonic acid metabolism_Homo sapiens_hsa005900.35881068
112Synaptic vesicle cycle_Homo sapiens_hsa047210.34188607
113Primary bile acid biosynthesis_Homo sapiens_hsa001200.34131058
114Viral carcinogenesis_Homo sapiens_hsa052030.34040918
115Peroxisome_Homo sapiens_hsa041460.31685478
116Systemic lupus erythematosus_Homo sapiens_hsa053220.30483119
117Pyruvate metabolism_Homo sapiens_hsa006200.29143346
118Herpes simplex infection_Homo sapiens_hsa051680.29128669
119Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.29018482
120Hedgehog signaling pathway_Homo sapiens_hsa043400.28204250
121TGF-beta signaling pathway_Homo sapiens_hsa043500.26055419
122Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.22147249
123Chemical carcinogenesis_Homo sapiens_hsa052040.22046154
124Acute myeloid leukemia_Homo sapiens_hsa052210.20593689
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.19913823
126Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.14922083
127Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.14808035
128Retinol metabolism_Homo sapiens_hsa008300.14448898
129Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.13136156
130Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.12721240
131Phenylalanine metabolism_Homo sapiens_hsa003600.12598826
132Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.11844992
133Apoptosis_Homo sapiens_hsa042100.11837663
134Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.10886587
135HTLV-I infection_Homo sapiens_hsa051660.09910314

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »