ATP10B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal absorption (GO:0050892)7.08262148
2maintenance of gastrointestinal epithelium (GO:0030277)6.02789842
3actin filament depolymerization (GO:0030042)5.85022462
4intestinal cholesterol absorption (GO:0030299)5.58047825
5angiotensin maturation (GO:0002003)5.47973360
6bundle of His cell to Purkinje myocyte communication (GO:0086069)5.36476493
7virion attachment to host cell (GO:0019062)4.93994887
8adhesion of symbiont to host cell (GO:0044650)4.93994887
9central nervous system myelination (GO:0022010)4.87080865
10axon ensheathment in central nervous system (GO:0032291)4.87080865
11tryptophan catabolic process (GO:0006569)4.75895771
12indole-containing compound catabolic process (GO:0042436)4.75895771
13indolalkylamine catabolic process (GO:0046218)4.75895771
14UDP-N-acetylglucosamine metabolic process (GO:0006047)4.74919813
15response to hepatocyte growth factor (GO:0035728)4.71788945
16cellular response to hepatocyte growth factor stimulus (GO:0035729)4.71788945
17positive regulation of actin filament depolymerization (GO:0030836)4.71669762
18hemidesmosome assembly (GO:0031581)4.58478074
19intestinal epithelial cell development (GO:0060576)4.56848902
20purine ribonucleoside bisphosphate metabolic process (GO:0034035)4.49362990
213-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)4.49362990
22O-glycan processing (GO:0016266)4.44826708
23sulfate transmembrane transport (GO:1902358)4.41666733
24indolalkylamine metabolic process (GO:0006586)4.37345416
25kynurenine metabolic process (GO:0070189)4.35649135
26cholesterol biosynthetic process (GO:0006695)4.28802701
27epithelial structure maintenance (GO:0010669)4.21954765
28digestive system process (GO:0022600)4.19065272
29calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.12163702
30detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)4.03864219
31cellular ketone body metabolic process (GO:0046950)4.00730533
32regulation of bile acid biosynthetic process (GO:0070857)3.97022951
33behavioral response to nicotine (GO:0035095)3.92710318
34tryptophan metabolic process (GO:0006568)3.92315118
35fatty acid elongation (GO:0030497)3.88540041
36vitamin A metabolic process (GO:0006776)3.86818197
37desmosome organization (GO:0002934)3.80900439
38adhesion of symbiont to host (GO:0044406)3.74818632
39diol metabolic process (GO:0034311)3.73818093
40ketone body metabolic process (GO:1902224)3.68760151
41sterol biosynthetic process (GO:0016126)3.68203082
42axon ensheathment (GO:0008366)3.64546834
43ensheathment of neurons (GO:0007272)3.64546834
44sulfate transport (GO:0008272)3.64313988
45sperm capacitation (GO:0048240)3.54174888
46regulation of viral release from host cell (GO:1902186)3.48959575
47sulfation (GO:0051923)3.47452084
48indole-containing compound metabolic process (GO:0042430)3.43271679
49bile acid and bile salt transport (GO:0015721)3.40671572
50thyroid hormone metabolic process (GO:0042403)3.40365594
51myelination (GO:0042552)3.38945421
52regulation of pigment cell differentiation (GO:0050932)3.38733714
53sphingosine metabolic process (GO:0006670)3.37743446
54sphingoid metabolic process (GO:0046519)3.36217334
55regulation of guanylate cyclase activity (GO:0031282)3.33796306
56regulation of establishment of cell polarity (GO:2000114)3.31699391
57regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.31024433
58flavonoid metabolic process (GO:0009812)3.30217473
59isoprenoid biosynthetic process (GO:0008299)3.28801903
60glycerophospholipid catabolic process (GO:0046475)3.27047745
61transepithelial transport (GO:0070633)3.26483394
62tight junction assembly (GO:0070830)3.25059109
63cilium or flagellum-dependent cell motility (GO:0001539)3.24072251
64serotonin metabolic process (GO:0042428)3.21259736
65eye photoreceptor cell differentiation (GO:0001754)3.21040754
66photoreceptor cell differentiation (GO:0046530)3.21040754
67detection of light stimulus involved in sensory perception (GO:0050962)3.20922649
68detection of light stimulus involved in visual perception (GO:0050908)3.20922649
69L-fucose catabolic process (GO:0042355)3.20833825
70fucose catabolic process (GO:0019317)3.20833825
71L-fucose metabolic process (GO:0042354)3.20833825
72long-chain fatty acid biosynthetic process (GO:0042759)3.19547696
73nucleotide transmembrane transport (GO:1901679)3.19477585
74primary amino compound metabolic process (GO:1901160)3.18582224
75fucosylation (GO:0036065)3.18056118
76asymmetric protein localization (GO:0008105)3.16625453
77signal peptide processing (GO:0006465)3.16183677
78auditory receptor cell stereocilium organization (GO:0060088)3.14857842
79positive regulation of fatty acid beta-oxidation (GO:0032000)3.13526635
80apical protein localization (GO:0045176)3.13211745
81behavioral response to ethanol (GO:0048149)3.12738763
82bicarbonate transport (GO:0015701)3.12099102
83negative regulation of keratinocyte proliferation (GO:0010839)3.11572218
84regulation of establishment or maintenance of cell polarity (GO:0032878)3.10092538
85photoreceptor cell maintenance (GO:0045494)3.09938264
86phosphatidylserine acyl-chain remodeling (GO:0036150)3.09881311
87regulation of RIG-I signaling pathway (GO:0039535)3.09490271
88reflex (GO:0060004)3.09087669
89neuronal action potential (GO:0019228)3.07596138
90neural tube formation (GO:0001841)3.07394628
91sex differentiation (GO:0007548)3.06108875
92positive regulation of fatty acid oxidation (GO:0046321)3.02938266
93amine catabolic process (GO:0009310)2.98667675
94cellular biogenic amine catabolic process (GO:0042402)2.98667675
95NAD biosynthetic process (GO:0009435)2.96329629
96sulfur compound transport (GO:0072348)2.94842499
97antibacterial humoral response (GO:0019731)2.94783631
98negative regulation of protein tyrosine kinase activity (GO:0061099)2.94643659
99regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.92343464
100protein O-linked glycosylation (GO:0006493)2.91412253
101proline transport (GO:0015824)2.91188018
102phosphatidylcholine biosynthetic process (GO:0006656)2.90896032
103positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.90868231
104positive regulation of guanylate cyclase activity (GO:0031284)2.89420298
105exogenous drug catabolic process (GO:0042738)2.87453743
106cellular glucuronidation (GO:0052695)2.87269189
107phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.87094553
108kidney morphogenesis (GO:0060993)2.87062827
109phosphatidylserine metabolic process (GO:0006658)2.86895316
110regulation of memory T cell differentiation (GO:0043380)2.86369695
111transcytosis (GO:0045056)2.86328139
112positive regulation of respiratory burst (GO:0060267)2.81011392
113negative regulation of mast cell activation (GO:0033004)2.79926854
114gamma-aminobutyric acid transport (GO:0015812)2.78980833
115antimicrobial humoral response (GO:0019730)2.78566612
116digestion (GO:0007586)2.76966525
117glucuronate metabolic process (GO:0019585)2.74537783
118uronic acid metabolic process (GO:0006063)2.74537783
119regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.73077453
120mucosal immune response (GO:0002385)2.72495680
121auditory receptor cell differentiation (GO:0042491)2.72165321
122benzene-containing compound metabolic process (GO:0042537)2.72136224
123amyloid precursor protein catabolic process (GO:0042987)2.72006087
124pyrimidine-containing compound transmembrane transport (GO:0072531)2.71342995
125cGMP-mediated signaling (GO:0019934)2.71140174
126regulation of water loss via skin (GO:0033561)2.70819495
127cellular anion homeostasis (GO:0030002)2.70080292
128protein K11-linked deubiquitination (GO:0035871)2.69026192
129peptidyl-tyrosine autophosphorylation (GO:0038083)2.68334253
130cytoplasmic mRNA processing body assembly (GO:0033962)2.67355412
131amyloid precursor protein metabolic process (GO:0042982)2.66954531
132long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.66932352
133negative regulation of cytosolic calcium ion concentration (GO:0051481)2.66160336
134establishment of protein localization to Golgi (GO:0072600)2.65919537
135regulation of action potential (GO:0098900)2.65917148
136positive regulation of pseudopodium assembly (GO:0031274)2.65491411
137oxidative demethylation (GO:0070989)2.65240854
138detection of mechanical stimulus involved in sensory perception (GO:0050974)2.64481487
139phosphatidylcholine metabolic process (GO:0046470)2.61371782
140magnesium ion transport (GO:0015693)2.60811660
141sphingomyelin metabolic process (GO:0006684)2.60391577
142striated muscle atrophy (GO:0014891)2.60180481
143hepatocyte apoptotic process (GO:0097284)2.59825965
144aromatic amino acid family catabolic process (GO:0009074)2.58478815
145alkaloid metabolic process (GO:0009820)2.58067340
146drug catabolic process (GO:0042737)2.57603620
147negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.57394632
148branching involved in labyrinthine layer morphogenesis (GO:0060670)2.57318440
149ethanolamine-containing compound metabolic process (GO:0042439)2.56822119
150muscle atrophy (GO:0014889)2.56041096
151organ or tissue specific immune response (GO:0002251)2.55507372
152fucose metabolic process (GO:0006004)2.55140362
153oligosaccharide catabolic process (GO:0009313)2.55015785
154phosphatidylinositol acyl-chain remodeling (GO:0036149)2.54685114
155regulation of hippo signaling (GO:0035330)2.54105268
156ventricular cardiac muscle cell action potential (GO:0086005)2.52572693
157filopodium assembly (GO:0046847)2.52548382
158cellular response to sterol (GO:0036315)2.51613698
159action potential (GO:0001508)2.51269293
160disruption of cells of other organism (GO:0044364)2.51195002
161killing of cells of other organism (GO:0031640)2.51195002
162negative regulation of multicellular organism growth (GO:0040015)2.50221999
163regulation of gene silencing by miRNA (GO:0060964)2.49109623
164regulation of gene silencing by RNA (GO:0060966)2.49109623
165regulation of posttranscriptional gene silencing (GO:0060147)2.49109623
166G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.48632537
167inner ear receptor stereocilium organization (GO:0060122)2.48499931
168membrane depolarization during action potential (GO:0086010)2.47341603
169regulation of MHC class I biosynthetic process (GO:0045343)2.45185797
170rRNA catabolic process (GO:0016075)2.44602030
171glomerular filtration (GO:0003094)2.44179839
172positive regulation of developmental pigmentation (GO:0048087)2.39841192
173tachykinin receptor signaling pathway (GO:0007217)2.38609190
174drug transmembrane transport (GO:0006855)2.32802778
175epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.32331714

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.17724940
2CDX2_20551321_ChIP-Seq_CACO-2_Human3.26321880
3TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.86341245
4CDX2_19796622_ChIP-Seq_MESCs_Mouse2.85817372
5EZH2_22144423_ChIP-Seq_EOC_Human2.64154824
6SOX2_27498859_Chip-Seq_STOMACH_Mouse2.54783539
7ZNF274_21170338_ChIP-Seq_K562_Hela2.47929627
8* SOX2_20726797_ChIP-Seq_SW620_Human2.21672146
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.21402474
10CTBP2_25329375_ChIP-Seq_LNCAP_Human2.19965173
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.14674281
12SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.11649200
13IGF1R_20145208_ChIP-Seq_DFB_Human2.11531771
14GATA4_25053715_ChIP-Seq_YYC3_Human2.05288917
15FLI1_27457419_Chip-Seq_LIVER_Mouse2.00597682
16ZNF217_24962896_ChIP-Seq_MCF-7_Human1.98659832
17TAF15_26573619_Chip-Seq_HEK293_Human1.95355281
18CTBP1_25329375_ChIP-Seq_LNCAP_Human1.87368791
19P300_19829295_ChIP-Seq_ESCs_Human1.83372287
20NR3C1_21868756_ChIP-Seq_MCF10A_Human1.75122261
21ESR1_20079471_ChIP-ChIP_T-47D_Human1.71362428
22SMAD_19615063_ChIP-ChIP_OVARY_Human1.69227478
23TCF4_18268006_ChIP-ChIP_LS174T_Human1.69074149
24FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.68690473
25FUS_26573619_Chip-Seq_HEK293_Human1.67144413
26SMAD4_21799915_ChIP-Seq_A2780_Human1.66987007
27PIAS1_25552417_ChIP-Seq_VCAP_Human1.63864007
28GATA6_25053715_ChIP-Seq_YYC3_Human1.58934729
29PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.58034218
30TCF4_23295773_ChIP-Seq_U87_Human1.56308597
31UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.55764088
32PPAR_26484153_Chip-Seq_NCI-H1993_Human1.55005142
33ESR2_21235772_ChIP-Seq_MCF-7_Human1.53709975
34GBX2_23144817_ChIP-Seq_PC3_Human1.52831852
35AR_25329375_ChIP-Seq_VCAP_Human1.52687324
36PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.51725274
37VDR_22108803_ChIP-Seq_LS180_Human1.50148511
38KLF5_25053715_ChIP-Seq_YYC3_Human1.49283960
39STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.44264179
40SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.44166974
41EWS_26573619_Chip-Seq_HEK293_Human1.44031544
42FOXO3_23340844_ChIP-Seq_DLD1_Human1.43322703
43CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.41003747
44ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.39792648
45CBP_20019798_ChIP-Seq_JUKART_Human1.38911576
46IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.38911576
47* DROSHA_22980978_ChIP-Seq_HELA_Human1.38689071
48CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.37207804
49* TCF4_22108803_ChIP-Seq_LS180_Human1.37182612
50TRIM28_21343339_ChIP-Seq_HEK293_Human1.36886642
51TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36761965
52TOP2B_26459242_ChIP-Seq_MCF-7_Human1.33530903
53TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33468606
54POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.33468606
55TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.31756037
56BMI1_23680149_ChIP-Seq_NPCS_Mouse1.31087351
57ESR1_21235772_ChIP-Seq_MCF-7_Human1.28853187
58SALL1_21062744_ChIP-ChIP_HESCs_Human1.28530425
59HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.28085725
60PCGF2_27294783_Chip-Seq_NPCs_Mouse1.27238129
61REST_21632747_ChIP-Seq_MESCs_Mouse1.26159085
62SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25813365
63EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.25349654
64FOXA1_21572438_ChIP-Seq_LNCaP_Human1.24959214
65* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.24920359
66AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.23863949
67IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.23365339
68* RUNX2_22187159_ChIP-Seq_PCA_Human1.23363741
69VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.22746043
70AHR_22903824_ChIP-Seq_MCF-7_Human1.20672259
71KLF5_20875108_ChIP-Seq_MESCs_Mouse1.20175216
72SMAD4_21741376_ChIP-Seq_EPCs_Human1.18553757
73RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18266820
74EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.17983580
75PCGF2_27294783_Chip-Seq_ESCs_Mouse1.16996306
76* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.16897266
77TP53_16413492_ChIP-PET_HCT116_Human1.15654102
78ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.15085960
79FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.14103490
80* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.13263172
81TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11667409
82SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.11353794
83GATA1_26923725_Chip-Seq_HPCs_Mouse1.11019762
84OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.10657018
85SOX2_21211035_ChIP-Seq_LN229_Gbm1.10282257
86SMAD3_21741376_ChIP-Seq_HESCs_Human1.09702222
87SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.09497890
88SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.09412764
89* NANOG_19829295_ChIP-Seq_ESCs_Human1.09402320
90* SOX2_19829295_ChIP-Seq_ESCs_Human1.09402320
91EZH2_27294783_Chip-Seq_ESCs_Mouse1.09357695
92AR_21572438_ChIP-Seq_LNCaP_Human1.09298721
93KDM2B_26808549_Chip-Seq_REH_Human1.09014658
94AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.08636930
95TAL1_26923725_Chip-Seq_HPCs_Mouse1.08432781
96* EGR1_23403033_ChIP-Seq_LIVER_Mouse1.08368366
97FOXA1_25552417_ChIP-Seq_VCAP_Human1.06891498
98SUZ12_18555785_Chip-Seq_ESCs_Mouse1.06868671
99CJUN_26792858_Chip-Seq_BT549_Human1.06560327
100* FLI1_21867929_ChIP-Seq_TH2_Mouse1.06234759
101SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05776885
102* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.05245603
103* FOXA1_25329375_ChIP-Seq_VCAP_Human1.05245603
104CRX_20693478_ChIP-Seq_RETINA_Mouse1.05090705
105* TP63_23658742_ChIP-Seq_EP156T_Human1.03870343
106SMAD3_21741376_ChIP-Seq_EPCs_Human1.02653784
107TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.02564705
108RNF2_18974828_ChIP-Seq_MESCs_Mouse1.02365094
109EZH2_18974828_ChIP-Seq_MESCs_Mouse1.02365094
110POU3F2_20337985_ChIP-ChIP_501MEL_Human1.02297704
111NANOG_18555785_Chip-Seq_ESCs_Mouse1.02119383
112MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.02116315
113STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.01967460
114SOX9_24532713_ChIP-Seq_HFSC_Mouse1.01809791
115SUZ12_27294783_Chip-Seq_ESCs_Mouse1.01290386
116STAT3_18555785_Chip-Seq_ESCs_Mouse1.01131473
117EZH2_27294783_Chip-Seq_NPCs_Mouse1.00717020
118MTF2_20144788_ChIP-Seq_MESCs_Mouse1.00202675
119* CDX2_22108803_ChIP-Seq_LS180_Human0.99845872
120GATA2_21666600_ChIP-Seq_HMVEC_Human0.99699740
121* ARNT_22903824_ChIP-Seq_MCF-7_Human0.99354141
122CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.99265269
123* ZFP57_27257070_Chip-Seq_ESCs_Mouse0.99164619
124SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.99014713
125CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.97733192
126ER_23166858_ChIP-Seq_MCF-7_Human0.97124781
127MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.97063792
128SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.95561805
129CBX2_27304074_Chip-Seq_ESCs_Mouse0.95445255
130NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.95232871
131NRF2_20460467_ChIP-Seq_MEFs_Mouse0.95232871
132CMYC_18555785_Chip-Seq_ESCs_Mouse0.95191887
133RUNX1_27514584_Chip-Seq_MCF-7_Human0.94907063
134EP300_21415370_ChIP-Seq_HL-1_Mouse0.93785608
135EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.93564882
136SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.93245204
137SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.92276347
138* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.92137506
139BCAT_22108803_ChIP-Seq_LS180_Human0.92095707
140RXR_22108803_ChIP-Seq_LS180_Human0.91518138
141STAT3_23295773_ChIP-Seq_U87_Human0.91433109
142P300_18555785_Chip-Seq_ESCs_Mouse0.90913716
143JARID2_20075857_ChIP-Seq_MESCs_Mouse0.90389679
144PRDM14_20953172_ChIP-Seq_ESCs_Human0.90151281
145NFE2_27457419_Chip-Seq_LIVER_Mouse0.89893788
146EED_16625203_ChIP-ChIP_MESCs_Mouse0.89773671
147E2F1_18555785_Chip-Seq_ESCs_Mouse0.88782414
148P53_22387025_ChIP-Seq_ESCs_Mouse0.88507464

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle6.02096089
2MP0000462_abnormal_digestive_system4.90188867
3MP0001666_abnormal_nutrient_absorption4.31737668
4MP0004264_abnormal_extraembryonic_tissu4.08206247
5MP0005360_urolithiasis3.96789069
6MP0000569_abnormal_digit_pigmentation3.42578763
7MP0010678_abnormal_skin_adnexa3.21290168
8MP0003866_abnormal_defecation3.09638720
9MP0001501_abnormal_sleep_pattern2.97819606
10MP0003195_calcinosis2.77559498
11MP0004147_increased_porphyrin_level2.62351593
12MP0005381_digestive/alimentary_phenotyp2.56472681
13MP0000566_synostosis2.53786661
14MP0000537_abnormal_urethra_morphology2.49419224
15MP0000383_abnormal_hair_follicle2.41069497
16MP0002822_catalepsy2.29929347
17MP0002796_impaired_skin_barrier2.28247981
18MP0005551_abnormal_eye_electrophysiolog2.25380504
19MP0001664_abnormal_digestion2.23081160
20MP0003950_abnormal_plasma_membrane2.21574582
21MP0001663_abnormal_digestive_system2.18646170
22MP0001968_abnormal_touch/_nociception2.18258214
23MP0002138_abnormal_hepatobiliary_system2.14636141
24MP0005451_abnormal_body_composition2.14319852
25MP0003183_abnormal_peptide_metabolism2.11212475
26MP0002736_abnormal_nociception_after2.06499013
27MP0002139_abnormal_hepatobiliary_system2.05312599
28MP0000538_abnormal_urinary_bladder2.01259733
29MP0003878_abnormal_ear_physiology2.00953478
30MP0005377_hearing/vestibular/ear_phenot2.00953478
31MP0008872_abnormal_physiological_respon1.97437421
32MP0010155_abnormal_intestine_physiology1.95397475
33MP0009745_abnormal_behavioral_response1.95161397
34MP0005365_abnormal_bile_salt1.93667864
35MP0000920_abnormal_myelination1.88981817
36MP0002098_abnormal_vibrissa_morphology1.84321749
37MP0009046_muscle_twitch1.84164089
38MP0005310_abnormal_salivary_gland1.84101671
39MP0005174_abnormal_tail_pigmentation1.82956615
40MP0003646_muscle_fatigue1.81754078
41MP0001873_stomach_inflammation1.80476020
42MP0000477_abnormal_intestine_morphology1.67116486
43MP0001485_abnormal_pinna_reflex1.65722111
44MP0002876_abnormal_thyroid_physiology1.63705714
45MP0005085_abnormal_gallbladder_physiolo1.63360705
46MP0004043_abnormal_pH_regulation1.62084672
47MP0001849_ear_inflammation1.61565551
48MP0004270_analgesia1.59069154
49MP0000579_abnormal_nail_morphology1.58806264
50MP0000230_abnormal_systemic_arterial1.55933399
51MP0002272_abnormal_nervous_system1.55115818
52MP0000467_abnormal_esophagus_morphology1.54647516
53MP0003453_abnormal_keratinocyte_physiol1.53923341
54MP0005646_abnormal_pituitary_gland1.51232591
55MP0001986_abnormal_taste_sensitivity1.49285325
56MP0008875_abnormal_xenobiotic_pharmacok1.48093460
57MP0002064_seizures1.48028535
58MP0005501_abnormal_skin_physiology1.46846207
59MP0006054_spinal_hemorrhage1.46765454
60MP0005670_abnormal_white_adipose1.43754188
61MP0002277_abnormal_respiratory_mucosa1.43661162
62MP0003011_delayed_dark_adaptation1.43119777
63MP0003252_abnormal_bile_duct1.41628214
64MP0004742_abnormal_vestibular_system1.40762732
65MP0003315_abnormal_perineum_morphology1.37701463
66MP0002733_abnormal_thermal_nociception1.37104906
67MP0001970_abnormal_pain_threshold1.36622454
68MP0002837_dystrophic_cardiac_calcinosis1.33958741
69MP0005253_abnormal_eye_physiology1.31171092
70MP0005645_abnormal_hypothalamus_physiol1.30874236
71MP0008004_abnormal_stomach_pH1.29078820
72MP0000490_abnormal_crypts_of1.27872830
73MP0005409_darkened_coat_color1.25662304
74MP0002102_abnormal_ear_morphology1.25273462
75MP0000427_abnormal_hair_cycle1.24434226
76MP0001216_abnormal_epidermal_layer1.24405609
77MP0003879_abnormal_hair_cell1.21754559
78MP0001765_abnormal_ion_homeostasis1.21402454
79MP0005386_behavior/neurological_phenoty1.19066308
80MP0004924_abnormal_behavior1.19066308
81MP0000762_abnormal_tongue_morphology1.18508325
82MP0001346_abnormal_lacrimal_gland1.18498956
83MP0002572_abnormal_emotion/affect_behav1.18240240
84MP0004019_abnormal_vitamin_homeostasis1.15008983
85MP0001756_abnormal_urination1.11707380
86MP0003300_gastrointestinal_ulcer1.11619104
87MP0002735_abnormal_chemical_nociception1.11518184
88MP0003938_abnormal_ear_development1.11432476
89MP0000470_abnormal_stomach_morphology1.09801951
90MP0000377_abnormal_hair_follicle1.08367416
91MP0004215_abnormal_myocardial_fiber1.07930573
92MP0004885_abnormal_endolymph1.07086466
93MP0006276_abnormal_autonomic_nervous1.06766358
94MP0003690_abnormal_glial_cell1.05449988
95MP0002638_abnormal_pupillary_reflex1.04872415
96MP0003718_maternal_effect1.03367568
97MP0010771_integument_phenotype1.02194318
98MP0002067_abnormal_sensory_capabilities1.00195257
99MP0009384_cardiac_valve_regurgitation1.00006627
100MP0008877_abnormal_DNA_methylation0.99566585
101MP0005171_absent_coat_pigmentation0.99391676
102MP0001764_abnormal_homeostasis0.98544412
103MP0002095_abnormal_skin_pigmentation0.98192841
104MP0010352_gastrointestinal_tract_polyps0.98179852
105MP0004142_abnormal_muscle_tone0.98076915
106MP0003937_abnormal_limbs/digits/tail_de0.96984559
107MP0003868_abnormal_feces_composition0.96375493
108MP0004782_abnormal_surfactant_physiolog0.95687508
109MP0000631_abnormal_neuroendocrine_gland0.95618452
110MP0004947_skin_inflammation0.94775957
111MP0003635_abnormal_synaptic_transmissio0.94486099
112MP0005448_abnormal_energy_balance0.94467842
113MP0002254_reproductive_system_inflammat0.93026855
114MP0002557_abnormal_social/conspecific_i0.92579598
115MP0003787_abnormal_imprinting0.92092103
116MP0002060_abnormal_skin_morphology0.91438142
117MP0003045_fibrosis0.90716673
118MP0004381_abnormal_hair_follicle0.87859077
119MP0005332_abnormal_amino_acid0.87727576
120MP0000613_abnormal_salivary_gland0.87353447
121MP0002063_abnormal_learning/memory/cond0.84881606
122MP0000015_abnormal_ear_pigmentation0.84067082
123MP0002118_abnormal_lipid_homeostasis0.81616149
124MP0004185_abnormal_adipocyte_glucose0.80014202
125MP0001963_abnormal_hearing_physiology0.79806132
126MP0003136_yellow_coat_color0.79689884
127MP0002938_white_spotting0.79517960
128MP0005167_abnormal_blood-brain_barrier0.79121701
129MP0006072_abnormal_retinal_apoptosis0.78807485
130MP0003119_abnormal_digestive_system0.78712898
131MP0003329_amyloid_beta_deposits0.77923813
132MP0010386_abnormal_urinary_bladder0.76991394
133MP0004145_abnormal_muscle_electrophysio0.76242093
134MP0002909_abnormal_adrenal_gland0.76116863
135MP0003633_abnormal_nervous_system0.74205918
136MP0001486_abnormal_startle_reflex0.71046618
137MP0001529_abnormal_vocalization0.70602961
138MP0005408_hypopigmentation0.70063221
139MP0004134_abnormal_chest_morphology0.69414436
140MP0000778_abnormal_nervous_system0.69386058
141MP0001177_atelectasis0.66632556
142MP0004272_abnormal_basement_membrane0.66596917
143MP0005367_renal/urinary_system_phenotyp0.63986498
144MP0000516_abnormal_urinary_system0.63986498
145MP0000647_abnormal_sebaceous_gland0.61963276
146MP0000026_abnormal_inner_ear0.61110640
147MP0005636_abnormal_mineral_homeostasis0.60542423
148MP0005275_abnormal_skin_tensile0.60175245
149MP0000604_amyloidosis0.59356440
150MP0000465_gastrointestinal_hemorrhage0.59242185
151MP0009643_abnormal_urine_homeostasis0.58374863
152MP0002734_abnormal_mechanical_nocicepti0.57605557
153MP0009840_abnormal_foam_cell0.56635239
154MP0010329_abnormal_lipoprotein_level0.55813375
155MP0001881_abnormal_mammary_gland0.53538244
156MP0002229_neurodegeneration0.52930013

Predicted human phenotypes

RankGene SetZ-score
1Ileus (HP:0002595)7.69021999
2Right ventricular cardiomyopathy (HP:0011663)5.60568346
3Genetic anticipation (HP:0003743)5.05432219
4Onycholysis (HP:0001806)4.37296812
5Degeneration of the lateral corticospinal tracts (HP:0002314)4.28341496
6Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.28341496
7Hyperventilation (HP:0002883)4.25975462
8Milia (HP:0001056)4.21465421
9Progressive cerebellar ataxia (HP:0002073)4.15518772
10Conjugated hyperbilirubinemia (HP:0002908)4.10952362
11Parakeratosis (HP:0001036)4.02772964
12Metabolic alkalosis (HP:0200114)4.01045866
13Pancreatic cysts (HP:0001737)4.00233309
14Congenital sensorineural hearing impairment (HP:0008527)3.93390351
15Gaze-evoked nystagmus (HP:0000640)3.76483780
16Atrophic scars (HP:0001075)3.70887504
17Congenital stationary night blindness (HP:0007642)3.66696336
18Acanthocytosis (HP:0001927)3.56495952
19Hyperactive renin-angiotensin system (HP:0000841)3.54295397
20True hermaphroditism (HP:0010459)3.50496256
21Chronic diarrhea (HP:0002028)3.48529623
22Congenital ichthyosiform erythroderma (HP:0007431)3.43989922
23Fragile nails (HP:0001808)3.43562583
24Pancreatic fibrosis (HP:0100732)3.40460958
25Abnormality of chloride homeostasis (HP:0011422)3.35967009
26Malnutrition (HP:0004395)3.27022526
27Esophageal atresia (HP:0002032)3.21279441
28Abnormality of small intestinal villus morphology (HP:0011472)3.20822503
29Villous atrophy (HP:0011473)3.20822503
30Abnormality of the renal cortex (HP:0011035)3.19023849
31Attenuation of retinal blood vessels (HP:0007843)3.18773179
32Abdominal distention (HP:0003270)3.18530815
33Dehydration (HP:0001944)3.14166984
34Abolished electroretinogram (ERG) (HP:0000550)3.01274587
35Abnormality of the corticospinal tract (HP:0002492)2.99344267
36Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.98420643
37Termporal pattern (HP:0011008)2.97859341
38Insidious onset (HP:0003587)2.97859341
39Pili torti (HP:0003777)2.96740389
40Clumsiness (HP:0002312)2.95120237
41Abnormality of midbrain morphology (HP:0002418)2.94948422
42Molar tooth sign on MRI (HP:0002419)2.94948422
43Male infertility (HP:0003251)2.93525885
44Curly hair (HP:0002212)2.84214986
45Plantar hyperkeratosis (HP:0007556)2.83492153
46Protruding tongue (HP:0010808)2.81954068
47Stomach cancer (HP:0012126)2.78422504
48Alkalosis (HP:0001948)2.78176707
49Symphalangism affecting the phalanges of the hand (HP:0009773)2.77648038
50Widely patent fontanelles and sutures (HP:0004492)2.75722279
51Cystic liver disease (HP:0006706)2.71627716
52Cone-rod dystrophy (HP:0000548)2.70684262
53Segmental peripheral demyelination/remyelination (HP:0003481)2.68503172
54Ureteral stenosis (HP:0000071)2.68392610
55Tubular atrophy (HP:0000092)2.66564229
56Abnormality of glutamine family amino acid metabolism (HP:0010902)2.63281709
57Sensory axonal neuropathy (HP:0003390)2.60925656
58Ureteral obstruction (HP:0006000)2.59167564
59Abnormality of the renal medulla (HP:0100957)2.57953769
60Hypoplasia of dental enamel (HP:0006297)2.57150246
61Nephronophthisis (HP:0000090)2.56690406
62Fair hair (HP:0002286)2.56255091
63Febrile seizures (HP:0002373)2.53963364
64Abnormality of renin-angiotensin system (HP:0000847)2.53676561
65Woolly hair (HP:0002224)2.53097773
66Aplasia/Hypoplasia of the tibia (HP:0005772)2.52378660
67Focal seizures (HP:0007359)2.51247822
68Chronic hepatic failure (HP:0100626)2.50294766
69Abnormality of potassium homeostasis (HP:0011042)2.48601700
70Inability to walk (HP:0002540)2.48390644
71Hyperphosphatemia (HP:0002905)2.47584316
72Hyperkalemia (HP:0002153)2.47526330
73Pendular nystagmus (HP:0012043)2.46565240
74Abnormality of the distal phalanx of the thumb (HP:0009617)2.46489870
75Congenital, generalized hypertrichosis (HP:0004540)2.45055521
76Large for gestational age (HP:0001520)2.43462617
77Dysmetric saccades (HP:0000641)2.43322652
78Focal motor seizures (HP:0011153)2.42866879
79Increased corneal curvature (HP:0100692)2.41202845
80Keratoconus (HP:0000563)2.41202845
81Progressive sensorineural hearing impairment (HP:0000408)2.41100569
82Hypokalemia (HP:0002900)2.40612059
83Increased neuronal autofluorescent lipopigment (HP:0002074)2.38898945
84Fat malabsorption (HP:0002630)2.38625633
85Aplasia cutis congenita (HP:0001057)2.36892943
86Furrowed tongue (HP:0000221)2.36485553
87Cupped ribs (HP:0000887)2.36309043
88Dialeptic seizures (HP:0011146)2.36280790
89Bony spicule pigmentary retinopathy (HP:0007737)2.36245708
90Decreased central vision (HP:0007663)2.35420167
91Broad-based gait (HP:0002136)2.34479609
92Hydroxyprolinuria (HP:0003080)2.32530738
93Abnormality of proline metabolism (HP:0010907)2.32530738
94Absent speech (HP:0001344)2.32490730
95Akinesia (HP:0002304)2.27693364
96Action tremor (HP:0002345)2.27638516
97Hypoplasia of the uterus (HP:0000013)2.27292965
98Abnormality of the vitamin B12 metabolism (HP:0004341)2.26783216
99Flat acetabular roof (HP:0003180)2.26387678
100Gastrointestinal dysmotility (HP:0002579)2.25886729
101Medial flaring of the eyebrow (HP:0010747)2.24359013
102Alopecia of scalp (HP:0002293)2.24270026
103Onion bulb formation (HP:0003383)2.23021231
104Generalized hypopigmentation of hair (HP:0011358)2.22964240
105Decreased electroretinogram (ERG) amplitude (HP:0000654)2.22817738
106Type II lissencephaly (HP:0007260)2.22554118
107Pustule (HP:0200039)2.22247548
108Autoimmune hemolytic anemia (HP:0001890)2.21916904
109Hyperaldosteronism (HP:0000859)2.20977612
110Enlarged epiphyses (HP:0010580)2.20833988
111Progressive inability to walk (HP:0002505)2.18948586
112Absence seizures (HP:0002121)2.18039154
113Abnormality of the 1st metacarpal (HP:0010009)2.16835509
114Abnormality of the middle phalanges of the toes (HP:0010183)2.16319112
115Ectropion (HP:0000656)2.13355454
116Dynein arm defect of respiratory motile cilia (HP:0012255)2.13017662
117Absent/shortened dynein arms (HP:0200106)2.13017662
118Abnormality of the 2nd finger (HP:0004100)2.11046965
119Renal cortical cysts (HP:0000803)2.09312413
120Goiter (HP:0000853)2.06977682
121Chorioretinal atrophy (HP:0000533)2.06889226
122Abnormal drinking behavior (HP:0030082)2.05754839
123Polydipsia (HP:0001959)2.05754839
124Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.05176376
125Abnormality of macular pigmentation (HP:0008002)2.03046597
126Abnormal biliary tract morphology (HP:0012440)2.02460619
127Mildly elevated creatine phosphokinase (HP:0008180)2.00248162
128Fragile skin (HP:0001030)2.00190235
129Abnormality of vitamin B metabolism (HP:0004340)1.99430105
130Syncope (HP:0001279)1.98291076
131Delayed epiphyseal ossification (HP:0002663)1.97336659
132Cerebellar dysplasia (HP:0007033)1.96697052
133Vascular calcification (HP:0004934)1.95913340
134Abnormality of magnesium homeostasis (HP:0004921)1.94290561
135Congenital hepatic fibrosis (HP:0002612)1.93885184
136Abnormality of alanine metabolism (HP:0010916)1.91982378
137Hyperalaninemia (HP:0003348)1.91982378
138Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.91982378
139Abnormal auditory evoked potentials (HP:0006958)1.89611026
140Pterygium (HP:0001059)1.89597740
141Hyperglycinuria (HP:0003108)1.88855743
142Neurofibrillary tangles (HP:0002185)1.88674243
143Pigmentary retinal degeneration (HP:0001146)1.88569016
144Retinitis pigmentosa (HP:0000510)1.88324850
145Gastrointestinal atresia (HP:0002589)1.87452474
146Central scotoma (HP:0000603)1.86876783
147Prostate neoplasm (HP:0100787)1.86377372
148Peripheral hypomyelination (HP:0007182)1.85659782
149Intrahepatic cholestasis (HP:0001406)1.85582220
150Ventricular fibrillation (HP:0001663)1.85535193
151Cupped ear (HP:0000378)1.85090449
152Premature skin wrinkling (HP:0100678)1.84616964
153Abnormality of the gastric mucosa (HP:0004295)1.84500435
154Abnormality of carpal bone ossification (HP:0006257)1.84298735
155Ulnar claw (HP:0001178)1.84053151
156Hypomagnesemia (HP:0002917)1.83648177
157Hoarse voice (HP:0001609)1.82343300
158Urinary bladder sphincter dysfunction (HP:0002839)1.82319868
159Biliary tract neoplasm (HP:0100574)1.80867497
160Proximal tubulopathy (HP:0000114)1.80347347
161Amelogenesis imperfecta (HP:0000705)1.79562824
162Sclerocornea (HP:0000647)1.79119756
163Gait imbalance (HP:0002141)1.78873057
164Hemiparesis (HP:0001269)1.78759874
165Increased IgE level (HP:0003212)1.78054668
166Hypoplasia of the fovea (HP:0007750)1.77812295
167Aplasia/Hypoplasia of the fovea (HP:0008060)1.77812295
168Hyperparathyroidism (HP:0000843)1.76775191
169Decreased circulating renin level (HP:0003351)1.76191826
170Abnormal rod and cone electroretinograms (HP:0008323)1.76090160
171Nail dystrophy (HP:0008404)1.74324563
172Focal segmental glomerulosclerosis (HP:0000097)1.74169943
173Abnormal tarsal ossification (HP:0008369)1.73916135
174White forelock (HP:0002211)1.73136515
175Abnormal hair laboratory examination (HP:0003328)1.71659935
176Progressive hearing impairment (HP:0001730)1.71578892
177Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.71140962
178Macular degeneration (HP:0000608)1.70925532
179Congenital primary aphakia (HP:0007707)1.70432501
180Abnormal ciliary motility (HP:0012262)1.70045740
181Scotoma (HP:0000575)1.68697133
182Aplasia/Hypoplasia of the tongue (HP:0010295)1.68127064

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST45.89359928
2FRK4.91500042
3ACVR1B4.88479105
4LMTK23.82384651
5MST1R3.70755054
6STK393.70394729
7EPHB13.18619236
8OXSR12.92763542
9ADRBK22.77571366
10TNIK2.77069955
11EPHA22.70083893
12PIK3CA2.55179670
13MET2.33974764
14NME12.08467719
15BCR1.96798412
16LATS11.92045390
17MAP2K21.87202144
18PRKG21.83701771
19INSRR1.65094841
20PINK11.61009986
21WNK31.54163548
22MAP3K21.51694756
23PBK1.49654886
24EPHB21.49284604
25ZAK1.48559303
26NUAK11.47934287
27NTRK31.38387556
28CDK191.36297647
29ERBB41.35677317
30FER1.25302162
31MAP4K21.21350173
32AKT31.21169842
33ADRBK11.20624302
34WNK41.17573527
35LIMK11.13919400
36DAPK21.13239727
37STK101.11865899
38MKNK21.09100497
39RIPK11.07728371
40TXK1.07630922
41MAP3K41.07446859
42CAMK2D1.02893985
43TAOK31.02568131
44TGFBR10.99848692
45TAOK10.99413612
46PTK20.99396759
47BMPR1B0.98658598
48IRAK10.98177397
49TESK10.98005484
50ICK0.92287589
51MAPKAPK50.90403558
52NEK60.90298121
53TLK10.90043052
54PKN10.87069367
55CAMK2B0.85219214
56TRPM70.84812350
57MAPKAPK30.84406770
58MYLK0.84059800
59DMPK0.83700533
60CAMKK20.80311463
61DDR20.79059707
62FGFR20.78348112
63PRKCI0.78324503
64PAK30.76892634
65MARK10.74038723
66KSR20.73017448
67ROCK20.72893550
68GRK10.72789824
69PRKAA20.72027359
70FGR0.71880184
71ERBB20.70810390
72CASK0.68686860
73PTK60.68028410
74EPHA40.66629160
75PTK2B0.64799983
76MAP2K10.64578590
77MAP2K60.63598232
78TTK0.63045699
79PIK3CG0.62324887
80PRKCG0.60739405
81CAMK2G0.59988911
82NLK0.59664338
83MELK0.59537773
84TEC0.58616174
85TYRO30.56409591
86STK240.55124057
87STK110.55027534
88STK30.53837672
89BMX0.51222747
90PRKCQ0.50964555
91MAP3K140.50741074
92MAPK130.50626552
93PDPK10.50013948
94SGK20.49583724
95MAP3K130.49410979
96GRK60.49369034
97CSNK1A1L0.49192754
98PRKCE0.48802670
99WNK10.48325551
100PNCK0.47469886
101MAP3K80.46911984
102EPHA30.46370648
103ROCK10.46162690
104SGK4940.46085466
105SGK2230.46085466
106KIT0.45989843
107IKBKE0.43001881
108PHKG10.42189237
109PHKG20.42189237
110TNK20.40950774
111MAP3K10.39263907
112TIE10.38858052
113CSNK1A10.37716434
114STK380.37451878
115PRKCZ0.36599876
116MATK0.36218642
117TBK10.35875373
118CSNK1G10.35353319
119PRKACA0.34998892
120IRAK20.34862851
121MAP2K70.34630737
122PAK10.34072418
123SGK10.33908493
124MAP3K70.33596975
125CAMK2A0.33358567
126TESK20.33356322
127CHUK0.32919835
128PRKAA10.32238095
129MARK20.31944382
130FYN0.31868436
131PRKG10.31503105
132NTRK20.31433463
133GRK50.29973110
134CSNK1G30.29670911
135IGF1R0.29647057
136CLK10.29573958
137ITK0.29451466
138ERBB30.29023330
139SRC0.28934624
140MAPK110.28269998
141YES10.28256993
142PRKCA0.28040502
143RPS6KB20.27832579
144DYRK20.27729799
145MUSK0.27600270
146STK38L0.27355740
147CSK0.27175777
148PAK60.26956207
149PRKACG0.26495790
150CSNK1G20.24453764
151MAPK150.24317024

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009204.54990552
2Mineral absorption_Homo sapiens_hsa049783.97419685
3Fat digestion and absorption_Homo sapiens_hsa049753.68132840
4Nitrogen metabolism_Homo sapiens_hsa009102.95593553
5Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.91553596
6Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.86980592
7Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.71039320
8Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.68532195
9Steroid biosynthesis_Homo sapiens_hsa001002.55816661
10Renin-angiotensin system_Homo sapiens_hsa046142.44928017
11Ether lipid metabolism_Homo sapiens_hsa005652.38280138
12Vitamin digestion and absorption_Homo sapiens_hsa049772.30495197
13Cyanoamino acid metabolism_Homo sapiens_hsa004602.26342683
14alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.24767504
15Primary bile acid biosynthesis_Homo sapiens_hsa001202.10150057
16Sphingolipid metabolism_Homo sapiens_hsa006002.05885297
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.99972167
18Linoleic acid metabolism_Homo sapiens_hsa005911.98148715
19Histidine metabolism_Homo sapiens_hsa003401.94194989
20Phototransduction_Homo sapiens_hsa047441.81183323
21Caffeine metabolism_Homo sapiens_hsa002321.76635496
22Nicotine addiction_Homo sapiens_hsa050331.72211598
23Fatty acid elongation_Homo sapiens_hsa000621.61977166
24Protein digestion and absorption_Homo sapiens_hsa049741.61695222
25Bile secretion_Homo sapiens_hsa049761.60602897
26Tight junction_Homo sapiens_hsa045301.58942141
27Arachidonic acid metabolism_Homo sapiens_hsa005901.40626993
28Taste transduction_Homo sapiens_hsa047421.40262960
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.37711326
30Carbohydrate digestion and absorption_Homo sapiens_hsa049731.32750309
31Galactose metabolism_Homo sapiens_hsa000521.28422989
32Glutathione metabolism_Homo sapiens_hsa004801.25136962
33Starch and sucrose metabolism_Homo sapiens_hsa005001.23272949
34Maturity onset diabetes of the young_Homo sapiens_hsa049501.21654525
35Folate biosynthesis_Homo sapiens_hsa007901.20824501
36Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.19400915
37Morphine addiction_Homo sapiens_hsa050321.13640346
38Olfactory transduction_Homo sapiens_hsa047401.13229148
39Pancreatic secretion_Homo sapiens_hsa049721.08482228
40Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.08376777
41Axon guidance_Homo sapiens_hsa043601.06059594
42Insulin secretion_Homo sapiens_hsa049111.04204810
43Fatty acid degradation_Homo sapiens_hsa000711.04097295
44Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.03030114
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.01011301
46Circadian entrainment_Homo sapiens_hsa047131.00947871
47Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.00530908
48Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00248262
49Fructose and mannose metabolism_Homo sapiens_hsa000510.98575470
50Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.95747746
51Asthma_Homo sapiens_hsa053100.94337609
52Thyroid hormone synthesis_Homo sapiens_hsa049180.93941729
53Propanoate metabolism_Homo sapiens_hsa006400.93895686
54Salivary secretion_Homo sapiens_hsa049700.92936355
55Glycerophospholipid metabolism_Homo sapiens_hsa005640.92037185
56Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.90832264
57Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.90167755
58Selenocompound metabolism_Homo sapiens_hsa004500.87254070
59Peroxisome_Homo sapiens_hsa041460.86724305
60Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.86233692
61Glycerolipid metabolism_Homo sapiens_hsa005610.83531838
62Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.82232155
63Drug metabolism - other enzymes_Homo sapiens_hsa009830.81928660
64Vibrio cholerae infection_Homo sapiens_hsa051100.79280072
65Arginine and proline metabolism_Homo sapiens_hsa003300.78631213
66Calcium signaling pathway_Homo sapiens_hsa040200.78564891
67GABAergic synapse_Homo sapiens_hsa047270.77059707
68Fatty acid biosynthesis_Homo sapiens_hsa000610.76902609
69Leukocyte transendothelial migration_Homo sapiens_hsa046700.76681055
70Ovarian steroidogenesis_Homo sapiens_hsa049130.72529325
71Salmonella infection_Homo sapiens_hsa051320.70909256
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.70762494
73Hepatitis C_Homo sapiens_hsa051600.69252861
74Butanoate metabolism_Homo sapiens_hsa006500.69094350
75Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.68420461
76Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.67038673
77ABC transporters_Homo sapiens_hsa020100.65945761
78Gastric acid secretion_Homo sapiens_hsa049710.64593817
79Adherens junction_Homo sapiens_hsa045200.63620384
80Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.63020562
81Steroid hormone biosynthesis_Homo sapiens_hsa001400.60435792
82ECM-receptor interaction_Homo sapiens_hsa045120.60416183
83Graft-versus-host disease_Homo sapiens_hsa053320.59108788
84Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.57094879
85Retinol metabolism_Homo sapiens_hsa008300.56301079
86Choline metabolism in cancer_Homo sapiens_hsa052310.55776800
87Long-term depression_Homo sapiens_hsa047300.54168558
88PPAR signaling pathway_Homo sapiens_hsa033200.53925793
89Dopaminergic synapse_Homo sapiens_hsa047280.53919290
90Arginine biosynthesis_Homo sapiens_hsa002200.52707217
91Serotonergic synapse_Homo sapiens_hsa047260.52042771
92Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.51889342
93Vascular smooth muscle contraction_Homo sapiens_hsa042700.51697279
94Cholinergic synapse_Homo sapiens_hsa047250.51075821
95Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.49885480
96Chemical carcinogenesis_Homo sapiens_hsa052040.47506337
97Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.47228085
98Cocaine addiction_Homo sapiens_hsa050300.46780810
99GnRH signaling pathway_Homo sapiens_hsa049120.45321861
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.45110732
101cAMP signaling pathway_Homo sapiens_hsa040240.44612238
102Tryptophan metabolism_Homo sapiens_hsa003800.43755209
103Type I diabetes mellitus_Homo sapiens_hsa049400.43027103
104Phosphatidylinositol signaling system_Homo sapiens_hsa040700.41408251
105Allograft rejection_Homo sapiens_hsa053300.40861063
106Autoimmune thyroid disease_Homo sapiens_hsa053200.40601015
107African trypanosomiasis_Homo sapiens_hsa051430.40141768
108Amphetamine addiction_Homo sapiens_hsa050310.37568333
109Aldosterone synthesis and secretion_Homo sapiens_hsa049250.36703200
110ErbB signaling pathway_Homo sapiens_hsa040120.34637693
111Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.33078825
112Oxytocin signaling pathway_Homo sapiens_hsa049210.32916738
113Dorso-ventral axis formation_Homo sapiens_hsa043200.31958142
114Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.31922855
115NOD-like receptor signaling pathway_Homo sapiens_hsa046210.31176191
116Intestinal immune network for IgA production_Homo sapiens_hsa046720.31103406
117Renin secretion_Homo sapiens_hsa049240.30922287
118Inositol phosphate metabolism_Homo sapiens_hsa005620.30882122
119Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.30444958
120Metabolic pathways_Homo sapiens_hsa011000.29874327
121Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29063363
122Regulation of actin cytoskeleton_Homo sapiens_hsa048100.28403985
123Amoebiasis_Homo sapiens_hsa051460.28027463
124Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.27582554
125Fatty acid metabolism_Homo sapiens_hsa012120.25667282
126Toxoplasmosis_Homo sapiens_hsa051450.25444161
127Hippo signaling pathway_Homo sapiens_hsa043900.25408829
128Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.24750307
129Ras signaling pathway_Homo sapiens_hsa040140.23885890
130Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.23743877
131Staphylococcus aureus infection_Homo sapiens_hsa051500.22736206
132Other glycan degradation_Homo sapiens_hsa005110.21973025
133Glutamatergic synapse_Homo sapiens_hsa047240.21456451
134Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.20954179
135Circadian rhythm_Homo sapiens_hsa047100.20897392
136Lysine degradation_Homo sapiens_hsa003100.20888255
137Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.20792060
138beta-Alanine metabolism_Homo sapiens_hsa004100.20685592
139Pertussis_Homo sapiens_hsa051330.19388942
140Phospholipase D signaling pathway_Homo sapiens_hsa040720.18639967
141Renal cell carcinoma_Homo sapiens_hsa052110.17457390

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