ATP13A1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1folic acid-containing compound biosynthetic process (GO:0009396)4.82304324
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.76171761
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.76171761
4mannose metabolic process (GO:0006013)4.66840477
5positive regulation of type I interferon-mediated signaling pathway (GO:0060340)4.37811781
6antigen processing and presentation of endogenous antigen (GO:0019883)4.09978699
7DNA unwinding involved in DNA replication (GO:0006268)3.96234414
8regulation of translational fidelity (GO:0006450)3.67332270
9NIK/NF-kappaB signaling (GO:0038061)3.67077119
10Golgi transport vesicle coating (GO:0048200)3.58210646
11COPI coating of Golgi vesicle (GO:0048205)3.58210646
12IMP biosynthetic process (GO:0006188)3.55820544
13ribosomal small subunit assembly (GO:0000028)3.47840804
14thymic T cell selection (GO:0045061)3.36075480
15mitotic G1 DNA damage checkpoint (GO:0031571)3.28727088
16negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.26961063
17negative regulation of cell killing (GO:0031342)3.26961063
18response to muramyl dipeptide (GO:0032495)3.26610265
19regulation of gamma-delta T cell differentiation (GO:0045586)3.25616878
20folic acid metabolic process (GO:0046655)3.25432544
21negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.22848499
22positive regulation of gamma-delta T cell activation (GO:0046645)3.22192027
23protein localization to endosome (GO:0036010)3.21510842
24apoptotic process involved in morphogenesis (GO:0060561)3.20559945
25maternal placenta development (GO:0001893)3.19929394
26tetrahydrofolate metabolic process (GO:0046653)3.19469154
27nucleobase biosynthetic process (GO:0046112)3.16596357
28negative regulation of cell size (GO:0045792)3.15281524
29modulation by symbiont of host cellular process (GO:0044068)3.10824628
30formation of translation preinitiation complex (GO:0001731)3.10653938
31positive regulation of Cdc42 GTPase activity (GO:0043089)3.10100180
32positive regulation by symbiont of host defense response (GO:0052509)3.07656466
33modulation by symbiont of host defense response (GO:0052031)3.07656466
34modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.07656466
35modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.07656466
36positive regulation by organism of defense response of other organism involved in symbiotic interact3.07656466
37modulation by symbiont of host immune response (GO:0052553)3.07656466
38mitotic G1/S transition checkpoint (GO:0044819)3.07459505
39response to type I interferon (GO:0034340)3.06540394
40cellular response to type I interferon (GO:0071357)3.06242300
41type I interferon signaling pathway (GO:0060337)3.06242300
42modulation by virus of host process (GO:0019054)3.05997656
43protein localization to kinetochore (GO:0034501)3.00826449
44IMP metabolic process (GO:0046040)3.00334429
45activation of Rac GTPase activity (GO:0032863)2.99824051
46response to peptidoglycan (GO:0032494)2.96660215
47viral transcription (GO:0019083)2.96552785
48antigen processing and presentation via MHC class Ib (GO:0002475)2.95275443
49negative regulation of RNA splicing (GO:0033119)2.93978851
50DNA strand elongation involved in DNA replication (GO:0006271)2.93547772
51pteridine-containing compound biosynthetic process (GO:0042559)2.92071351
52retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.91076368
53cellular response to virus (GO:0098586)2.90478005
54response to laminar fluid shear stress (GO:0034616)2.89339706
55activation of MAPKKK activity (GO:0000185)2.89120781
56translational termination (GO:0006415)2.88681689
57mitotic nuclear envelope disassembly (GO:0007077)2.86567379
58regulation of gamma-delta T cell activation (GO:0046643)2.85540205
59positive regulation of histone deacetylation (GO:0031065)2.85242409
60negative regulation of erythrocyte differentiation (GO:0045647)2.85101369
61pentose-phosphate shunt (GO:0006098)2.84574579
62pinocytosis (GO:0006907)2.83968069
63germinal center formation (GO:0002467)2.82723207
64regulation of extracellular matrix disassembly (GO:0010715)2.81917540
65regulation of histone H3-K27 methylation (GO:0061085)2.81554995
66detection of bacterium (GO:0016045)2.80762753
67nuclear pore complex assembly (GO:0051292)2.79725228
68positive regulation of nuclease activity (GO:0032075)2.79000447
69nuclear pore organization (GO:0006999)2.78085629
70DNA replication initiation (GO:0006270)2.77341679
71negative regulation of mRNA metabolic process (GO:1903312)2.76568292
72negative regulation of mRNA processing (GO:0050686)2.76445505
73protein retention in ER lumen (GO:0006621)2.76043586
74translational elongation (GO:0006414)2.75662256
75activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.75398934
76DNA duplex unwinding (GO:0032508)2.75104532
77semaphorin-plexin signaling pathway (GO:0071526)2.74512676
78T cell selection (GO:0045058)2.73803965
79regulation of translational termination (GO:0006449)2.73012173
80folic acid-containing compound metabolic process (GO:0006760)2.72940744
81DNA strand elongation (GO:0022616)2.72938007
82glycine metabolic process (GO:0006544)2.72279293
83DNA geometric change (GO:0032392)2.71694637
84adherens junction assembly (GO:0034333)2.71645088
85cell-substrate adherens junction assembly (GO:0007045)2.70704170
86focal adhesion assembly (GO:0048041)2.70704170
87pre-miRNA processing (GO:0031054)2.70115565
88SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.69656839
89proline biosynthetic process (GO:0006561)2.69632832
90negative regulation of viral release from host cell (GO:1902187)2.68602411
91translesion synthesis (GO:0019985)2.67340831
92embryonic process involved in female pregnancy (GO:0060136)2.66055023
93regulation of early endosome to late endosome transport (GO:2000641)2.65777838
94detection of other organism (GO:0098543)2.65739783
95membrane disassembly (GO:0030397)2.64913441
96nuclear envelope disassembly (GO:0051081)2.64913441
97regulation of nuclease activity (GO:0032069)2.64847967
98G1 DNA damage checkpoint (GO:0044783)2.64361363
99spliceosomal tri-snRNP complex assembly (GO:0000244)2.63893463
100intracellular estrogen receptor signaling pathway (GO:0030520)2.63687962
101nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.63078109
102maturation of SSU-rRNA (GO:0030490)2.62713820
103protein targeting to ER (GO:0045047)2.59902191
104macrophage activation involved in immune response (GO:0002281)2.59703652
105regulation of mammary gland epithelial cell proliferation (GO:0033599)2.59601187
106epithelial cell differentiation involved in prostate gland development (GO:0060742)2.59009559
107L-alpha-amino acid transmembrane transport (GO:1902475)2.58932110
108one-carbon metabolic process (GO:0006730)2.58718475
109regulation of NFAT protein import into nucleus (GO:0051532)2.57904774
110negative thymic T cell selection (GO:0045060)2.57802668
111antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.57680700
112ncRNA 3-end processing (GO:0043628)2.56574779
113basement membrane organization (GO:0071711)2.56009021
114cotranslational protein targeting to membrane (GO:0006613)2.55628394
115translational initiation (GO:0006413)2.54130903
116regulation of defense response to virus by virus (GO:0050690)2.53452733
117leukocyte aggregation (GO:0070486)2.53361802
118pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.53249314
119UMP biosynthetic process (GO:0006222)2.53249314
120pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.53249314
121UMP metabolic process (GO:0046049)2.53249314
122regulation of dendritic cell antigen processing and presentation (GO:0002604)2.53115361
123positive thymic T cell selection (GO:0045059)2.52733593
124regulation of ARF GTPase activity (GO:0032312)2.51598517
125stress fiber assembly (GO:0043149)2.50603942
126purine nucleobase biosynthetic process (GO:0009113)2.50294699
127lipopolysaccharide-mediated signaling pathway (GO:0031663)2.49701692
128telomere maintenance via semi-conservative replication (GO:0032201)2.49113602
129mRNA stabilization (GO:0048255)2.48703938
130RNA stabilization (GO:0043489)2.48703938
131establishment of protein localization to endoplasmic reticulum (GO:0072599)2.48499102
132T cell apoptotic process (GO:0070231)2.48233490
133regulation of glucose import in response to insulin stimulus (GO:2001273)2.47520124
134negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.46825587
135heterochromatin organization (GO:0070828)2.45922189
136immunoglobulin mediated immune response (GO:0016064)2.45060177
137negative regulation of histone methylation (GO:0031061)2.43889796
138histone mRNA catabolic process (GO:0071044)2.43280545
139positive regulation of B cell differentiation (GO:0045579)2.42383944
140activation of JUN kinase activity (GO:0007257)2.42337840
141myeloid dendritic cell differentiation (GO:0043011)2.42253721
142endoplasmic reticulum unfolded protein response (GO:0030968)2.41812286
1433-UTR-mediated mRNA stabilization (GO:0070935)2.41751080
144pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.41559968
145valine metabolic process (GO:0006573)2.40828601
146poly(A)+ mRNA export from nucleus (GO:0016973)2.40326353
147regulation of chromatin binding (GO:0035561)2.40294335
148B cell receptor signaling pathway (GO:0050853)2.38982488
149protein localization to endoplasmic reticulum (GO:0070972)2.38851794
150positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.38803014
151regulation of interferon-beta biosynthetic process (GO:0045357)2.38121807
152cellular response to interleukin-4 (GO:0071353)2.37818922
153negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.37788543
154regulation of cholesterol homeostasis (GO:2000188)2.37658891
155snRNA metabolic process (GO:0016073)2.37580852
156positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.36670672
157retrograde transport, endosome to Golgi (GO:0042147)2.35546561
158signal complex assembly (GO:0007172)2.35248151
159protein localization to chromosome, centromeric region (GO:0071459)2.34409986
160regulation of type I interferon-mediated signaling pathway (GO:0060338)2.34021063
161dosage compensation (GO:0007549)2.33854471
162NADPH regeneration (GO:0006740)2.33761738
163cell-substrate junction assembly (GO:0007044)2.32916475
164natural killer cell differentiation (GO:0001779)2.31899319
165barbed-end actin filament capping (GO:0051016)2.31550192
166regulation of T-helper 2 cell differentiation (GO:0045628)2.31549085
167peptidyl-lysine dimethylation (GO:0018027)2.30913555
168regulation of leukocyte degranulation (GO:0043300)2.30856731
169negative T cell selection (GO:0043383)2.30662834
170histone H4 deacetylation (GO:0070933)2.30057553
171positive regulation of protein deacetylation (GO:0090312)2.29965800
172serine family amino acid biosynthetic process (GO:0009070)2.29877088
173maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.29598216
174cellular response to unfolded protein (GO:0034620)2.29406744
175regulation of histone H3-K9 methylation (GO:0051570)2.29007207
176CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.27667140
177lipopolysaccharide biosynthetic process (GO:0009103)2.26965056
178nuclear envelope organization (GO:0006998)2.24292217
179viral life cycle (GO:0019058)2.22723610
180lymphocyte apoptotic process (GO:0070227)2.22315230

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.99178884
2MYC_22102868_ChIP-Seq_BL_Human3.26090431
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.10894704
4EGR1_19374776_ChIP-ChIP_THP-1_Human2.97245445
5* MYC_18555785_ChIP-Seq_MESCs_Mouse2.70836207
6TP63_17297297_ChIP-ChIP_HaCaT_Human2.68272222
7THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.55525303
8FOXM1_23109430_ChIP-Seq_U2OS_Human2.54873497
9VDR_21846776_ChIP-Seq_THP-1_Human2.34278329
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.21351723
11RARG_19884340_ChIP-ChIP_MEFs_Mouse2.04804513
12* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.04533676
13ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.92020524
14IRF8_22096565_ChIP-ChIP_GC-B_Human1.88076054
15* CIITA_25753668_ChIP-Seq_RAJI_Human1.78377375
16TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.75418017
17E2F4_17652178_ChIP-ChIP_JURKAT_Human1.73873852
18* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.73820082
19EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.72863314
20FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.72442601
21* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.72250702
22TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.72102439
23* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.72096303
24* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.71303343
25ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.67293790
26STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.67256462
27TCF7_22412390_ChIP-Seq_EML_Mouse1.66797508
28MAF_26560356_Chip-Seq_TH1_Human1.63155889
29XRN2_22483619_ChIP-Seq_HELA_Human1.62250942
30P68_20966046_ChIP-Seq_HELA_Human1.60501017
31UTX_26944678_Chip-Seq_JUKART_Human1.58546821
32KDM2B_26808549_Chip-Seq_K562_Human1.52595205
33CTCF_27219007_Chip-Seq_ERYTHROID_Human1.51857158
34KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.50813740
35PPARA_22158963_ChIP-Seq_LIVER_Mouse1.48984663
36E2F1_21310950_ChIP-Seq_MCF-7_Human1.48770903
37ELK3_25401928_ChIP-Seq_HUVEC_Human1.48077492
38MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.46990644
39SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.46974070
40SA1_27219007_Chip-Seq_ERYTHROID_Human1.45849053
41TET1_21451524_ChIP-Seq_MESCs_Mouse1.45804401
42* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.44996622
43SMC4_20622854_ChIP-Seq_HELA_Human1.41357018
44KDM2B_26808549_Chip-Seq_JURKAT_Human1.41125213
45KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.38947678
46* ETS1_20019798_ChIP-Seq_JURKAT_Human1.38630985
47NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.38283272
48* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.38265468
49KDM5A_27292631_Chip-Seq_BREAST_Human1.37781989
50STAT6_21828071_ChIP-Seq_BEAS2B_Human1.36422438
51* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.36030577
52ZFP281_18757296_ChIP-ChIP_E14_Mouse1.35542403
53E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.35412860
54BRD4_27068464_Chip-Seq_AML-cells_Mouse1.34561801
55KDM2B_26808549_Chip-Seq_DND41_Human1.34503128
56* MYB_26560356_Chip-Seq_TH1_Human1.34337188
57ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.34147405
58TFEB_21752829_ChIP-Seq_HELA_Human1.33611484
59STAT3_1855785_ChIP-Seq_MESCs_Mouse1.32125164
60UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.31778820
61MYB_21317192_ChIP-Seq_ERMYB_Mouse1.30968383
62VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.30801872
63SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.30563245
64* ELF1_20517297_ChIP-Seq_JURKAT_Human1.30518074
65TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.30216949
66RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.27961163
67POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.27206951
68IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.26746517
69MYB_26560356_Chip-Seq_TH2_Human1.26113742
70STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.26107267
71KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.25779989
72* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.25748496
73PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.25410842
74* GABP_19822575_ChIP-Seq_HepG2_Human1.25066847
75CREB1_26743006_Chip-Seq_LNCaP_Human1.24888347
76BCOR_27268052_Chip-Seq_Bcells_Human1.24377287
77VDR_24763502_ChIP-Seq_THP-1_Human1.23956339
78POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.23154380
79* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.22948906
80MYCN_18555785_ChIP-Seq_MESCs_Mouse1.22942582
81* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.22687570
82SRY_22984422_ChIP-ChIP_TESTIS_Rat1.22627046
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.22175095
84NANOG_18555785_ChIP-Seq_MESCs_Mouse1.22153119
85* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.21949080
86* LXR_22292898_ChIP-Seq_THP-1_Human1.21895074
87ELF1_17652178_ChIP-ChIP_JURKAT_Human1.21430690
88RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.21252833
89RXR_22158963_ChIP-Seq_LIVER_Mouse1.21028409
90SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.20552396
91CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.20421876
92VDR_23849224_ChIP-Seq_CD4+_Human1.19745157
93RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.19672995
94ESR2_21235772_ChIP-Seq_MCF-7_Human1.19668494
95SPI1_23547873_ChIP-Seq_NB4_Human1.19507609
96RUNX1_22412390_ChIP-Seq_EML_Mouse1.19146472
97AR_21909140_ChIP-Seq_LNCAP_Human1.18819748
98MAF_26560356_Chip-Seq_TH2_Human1.18426912
99* FOXP3_21729870_ChIP-Seq_TREG_Human1.17274455
100PU.1_20513432_ChIP-Seq_Bcells_Mouse1.17043134
101EST1_17652178_ChIP-ChIP_JURKAT_Human1.16941776
102* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.16786111
103E2F1_18555785_ChIP-Seq_MESCs_Mouse1.16271744
104BCL6_27268052_Chip-Seq_Bcells_Human1.15257050
105* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.14153764
106SCL_19346495_ChIP-Seq_HPC-7_Human1.13815644
107GATA1_22383799_ChIP-Seq_G1ME_Mouse1.13775674
108GATA1_19941827_ChIP-Seq_MEL_Mouse1.12631394
109CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11835203
110SPI1_23127762_ChIP-Seq_K562_Human1.11213485
111MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.11199013
112KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.10710956
113ERG_21242973_ChIP-ChIP_JURKAT_Human1.10510191
114* DCP1A_22483619_ChIP-Seq_HELA_Human1.09905403
115CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.09757233
116SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.09533107
117GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.09434770
118CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.08828076
119TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08276028
120NCOR1_26117541_ChIP-Seq_K562_Human1.08244299
121KDM2B_26808549_Chip-Seq_SUP-B15_Human1.07650575
122CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.07191004
123CREB1_15753290_ChIP-ChIP_HEK293T_Human1.06904780
124ATF3_27146783_Chip-Seq_COLON_Human1.06631750
125NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.05034709
126GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04729169
127ZNF263_19887448_ChIP-Seq_K562_Human1.04635207
128MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.04442481
129RACK7_27058665_Chip-Seq_MCF-7_Human1.04303158
130SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.04093801
131KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.02982585
132GATA1_22025678_ChIP-Seq_K562_Human1.02760698
133DNAJC2_21179169_ChIP-ChIP_NT2_Human1.02533772
134CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01743342
135PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.01578766
136CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01559868
137TP53_22127205_ChIP-Seq_IMR90_Human1.01246618
138RUNX1_27514584_Chip-Seq_MCF-7_Human1.01207692
139SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.01191275
140NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.00847340
141TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.99480233
142DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.99406579
143STAT4_19710469_ChIP-ChIP_TH1__Mouse0.99363957
144TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.98870402
145CLOCK_20551151_ChIP-Seq_293T_Human0.95891525
146CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.94852021
147* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.94823720
148HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.93598772
149CHD1_26751641_Chip-Seq_LNCaP_Human0.92357494

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005451_abnormal_body_composition3.19298693
2MP0010352_gastrointestinal_tract_polyps3.09192407
3MP0003705_abnormal_hypodermis_morpholog2.65211537
4MP0003693_abnormal_embryo_hatching2.58637151
5MP0008260_abnormal_autophagy2.40347773
6MP0002396_abnormal_hematopoietic_system2.38940005
7MP0003300_gastrointestinal_ulcer2.13893348
8MP0003111_abnormal_nucleus_morphology2.13724723
9MP0004957_abnormal_blastocyst_morpholog2.10281501
10MP0000685_abnormal_immune_system1.96423295
11MP0010094_abnormal_chromosome_stability1.95143896
12MP0003763_abnormal_thymus_physiology1.93900821
13MP0003077_abnormal_cell_cycle1.91050508
14MP0009840_abnormal_foam_cell1.90858936
15MP0005076_abnormal_cell_differentiation1.87767644
16MP0004858_abnormal_nervous_system1.81861106
17MP0002139_abnormal_hepatobiliary_system1.80789805
18MP0003453_abnormal_keratinocyte_physiol1.73979075
19MP0001348_abnormal_lacrimal_gland1.72548614
20MP0001835_abnormal_antigen_presentation1.69457164
21MP0004808_abnormal_hematopoietic_stem1.68681460
22MP0005360_urolithiasis1.68495396
23MP0000490_abnormal_crypts_of1.67530671
24MP0010234_abnormal_vibrissa_follicle1.66764661
25MP0009333_abnormal_splenocyte_physiolog1.64901629
26MP0001800_abnormal_humoral_immune1.64825308
27MP0003436_decreased_susceptibility_to1.64364606
28MP0008057_abnormal_DNA_replication1.63289812
29MP0002398_abnormal_bone_marrow1.62082089
30MP0010307_abnormal_tumor_latency1.61564598
31MP0003091_abnormal_cell_migration1.61373672
32MP0003303_peritoneal_inflammation1.60891959
33MP0005365_abnormal_bile_salt1.57433542
34MP0003566_abnormal_cell_adhesion1.54245772
35MP0001545_abnormal_hematopoietic_system1.48812714
36MP0005397_hematopoietic_system_phenotyp1.48812714
37MP0002722_abnormal_immune_system1.46811858
38MP0000689_abnormal_spleen_morphology1.46540801
39MP0002166_altered_tumor_susceptibility1.45682209
40MP0004947_skin_inflammation1.45051487
41MP0003806_abnormal_nucleotide_metabolis1.44791884
42MP0004381_abnormal_hair_follicle1.44710323
43MP0009278_abnormal_bone_marrow1.44351902
44MP0001730_embryonic_growth_arrest1.44055533
45MP0000678_abnormal_parathyroid_gland1.43256979
46MP0001533_abnormal_skeleton_physiology1.41877390
47MP0000703_abnormal_thymus_morphology1.41132548
48MP0008007_abnormal_cellular_replicative1.38459901
49MP0001873_stomach_inflammation1.38435661
50MP0000350_abnormal_cell_proliferation1.38265001
51MP0005083_abnormal_biliary_tract1.36072592
52MP0002452_abnormal_antigen_presenting1.35916803
53MP0005023_abnormal_wound_healing1.35629302
54MP0008438_abnormal_cutaneous_collagen1.35546827
55MP0004510_myositis1.35464287
56MP0002877_abnormal_melanocyte_morpholog1.35287433
57MP0002254_reproductive_system_inflammat1.34825017
58MP0010155_abnormal_intestine_physiology1.32942028
59MP0001790_abnormal_immune_system1.32809931
60MP0005387_immune_system_phenotype1.32809931
61MP0000716_abnormal_immune_system1.31943328
62MP0005671_abnormal_response_to1.31677762
63MP0003172_abnormal_lysosome_physiology1.28559343
64MP0002998_abnormal_bone_remodeling1.27199351
65MP0002420_abnormal_adaptive_immunity1.27087360
66MP0005220_abnormal_exocrine_pancreas1.27063599
67MP0002429_abnormal_blood_cell1.27037399
68MP0002723_abnormal_immune_serum1.26309152
69MP0001666_abnormal_nutrient_absorption1.26121858
70MP0003191_abnormal_cellular_cholesterol1.25852042
71MP0006082_CNS_inflammation1.25733594
72MP0001819_abnormal_immune_cell1.25287121
73MP0002019_abnormal_tumor_incidence1.24235995
74MP0004264_abnormal_extraembryonic_tissu1.23219696
75MP0002148_abnormal_hypersensitivity_rea1.23141973
76MP0000609_abnormal_liver_physiology1.22165999
77MP0004197_abnormal_fetal_growth/weight/1.21035301
78MP0002796_impaired_skin_barrier1.20989564
79MP0005025_abnormal_response_to1.20741848
80MP0006054_spinal_hemorrhage1.19051706
81MP0003866_abnormal_defecation1.15355958
82MP0005464_abnormal_platelet_physiology1.14096945
83MP0002405_respiratory_system_inflammati1.13532515
84MP0002086_abnormal_extraembryonic_tissu1.13483269
85MP0005000_abnormal_immune_tolerance1.12280610
86MP0002089_abnormal_postnatal_growth/wei1.10991368
87MP0005058_abnormal_lysosome_morphology1.10411083
88MP0000598_abnormal_liver_morphology1.09036256
89MP0002080_prenatal_lethality1.08222840
90MP0003984_embryonic_growth_retardation1.08137902
91MP0001853_heart_inflammation1.07288710
92MP0000858_altered_metastatic_potential1.07018505
93MP0002088_abnormal_embryonic_growth/wei1.07008994
94MP0001672_abnormal_embryogenesis/_devel1.06577781
95MP0005380_embryogenesis_phenotype1.06577781
96MP0005409_darkened_coat_color1.06013802
97MP0005310_abnormal_salivary_gland1.05838261
98MP0005501_abnormal_skin_physiology1.04439216
99MP0005666_abnormal_adipose_tissue1.04385757
100MP0000537_abnormal_urethra_morphology1.04182619
101MP0001697_abnormal_embryo_size1.03965560
102MP0001845_abnormal_inflammatory_respons1.03514557
103MP0003183_abnormal_peptide_metabolism1.03029703
104MP0005621_abnormal_cell_physiology1.02009702
105MP0003279_aneurysm1.01005906
106MP0005085_abnormal_gallbladder_physiolo1.00614000
107MP0000003_abnormal_adipose_tissue1.00474076
108MP0004185_abnormal_adipocyte_glucose0.97976584
109MP0000313_abnormal_cell_death0.97519146
110MP0009785_altered_susceptibility_to0.97472515
111MP0005375_adipose_tissue_phenotype0.96494788
112MP0000477_abnormal_intestine_morphology0.96454208
113MP0002933_joint_inflammation0.96220454
114MP0003329_amyloid_beta_deposits0.94910299
115MP0002006_tumorigenesis0.93586555
116MP0003252_abnormal_bile_duct0.93165742
117MP0003724_increased_susceptibility_to0.91335603
118MP0000465_gastrointestinal_hemorrhage0.89472053
119MP0002084_abnormal_developmental_patter0.89351311
120MP0002060_abnormal_skin_morphology0.88296814
121MP0000604_amyloidosis0.88179543
122MP0003075_altered_response_to0.87389003
123MP0008058_abnormal_DNA_repair0.86837987
124MP0002419_abnormal_innate_immunity0.86354770
125MP0008961_abnormal_basal_metabolism0.86165181
126MP0010329_abnormal_lipoprotein_level0.85887749
127MP0001849_ear_inflammation0.85386724
128MP0009931_abnormal_skin_appearance0.83078881
129MP0009643_abnormal_urine_homeostasis0.82951212
130MP0002085_abnormal_embryonic_tissue0.82053566
131MP0008469_abnormal_protein_level0.82035547
132MP0001216_abnormal_epidermal_layer0.80432530
133MP0005390_skeleton_phenotype0.79725565
134MP0001915_intracranial_hemorrhage0.79469159
135MP0000358_abnormal_cell_content/0.79262473
136MP0001851_eye_inflammation0.78723547
137MP0009672_abnormal_birth_weight0.78156174
138MP0003448_altered_tumor_morphology0.77983216
139MP0005257_abnormal_intraocular_pressure0.76960249
140MP0002132_abnormal_respiratory_system0.75954565
141MP0004233_abnormal_muscle_weight0.73252989
142MP0000733_abnormal_muscle_development0.72797768
143MP0003795_abnormal_bone_structure0.70904280

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)3.27827468
2Ependymoma (HP:0002888)3.19225601
3Broad face (HP:0000283)3.07046931
4Abnormality of the fingertips (HP:0001211)3.06278100
5Increased IgE level (HP:0003212)2.90500209
6Thrombocytosis (HP:0001894)2.88979622
7Chronic otitis media (HP:0000389)2.75506260
8Basal cell carcinoma (HP:0002671)2.75122949
9Dysostosis multiplex (HP:0000943)2.71386435
10Obstructive sleep apnea (HP:0002870)2.64214615
11J-shaped sella turcica (HP:0002680)2.63525687
12Spastic diplegia (HP:0001264)2.61775675
13Abnormality of macrophages (HP:0004311)2.59626699
14Increased cerebral lipofuscin (HP:0011813)2.56400815
15Nasal polyposis (HP:0100582)2.50747156
16Loss of speech (HP:0002371)2.49172053
17Recurrent viral infections (HP:0004429)2.43740728
18Abnormality of cells of the erythroid lineage (HP:0012130)2.42727943
19Recurrent abscess formation (HP:0002722)2.41551787
20Vertebral compression fractures (HP:0002953)2.41168849
21Hemorrhage of the eye (HP:0011885)2.37101314
22Recurrent bacterial skin infections (HP:0005406)2.36801568
23Hyperacusis (HP:0010780)2.36153015
24IgM deficiency (HP:0002850)2.35837366
25Abnormality of the nasal mucosa (HP:0000433)2.30814413
26Hand muscle atrophy (HP:0009130)2.30779839
27Long palpebral fissure (HP:0000637)2.29098543
28Distal lower limb amyotrophy (HP:0008944)2.28827511
29Gastrointestinal stroma tumor (HP:0100723)2.26218265
30Increased neuronal autofluorescent lipopigment (HP:0002074)2.25920246
31Abnormal number of erythroid precursors (HP:0012131)2.22525005
32Protrusio acetabuli (HP:0003179)2.22421272
33Abnormality of T cell physiology (HP:0011840)2.18734189
34Cerebral aneurysm (HP:0004944)2.18342163
35Flat acetabular roof (HP:0003180)2.18074275
36Urinary glycosaminoglycan excretion (HP:0003541)2.15853679
37Mucopolysacchariduria (HP:0008155)2.15853679
38Gastrointestinal inflammation (HP:0004386)2.15847225
39Recurrent bronchitis (HP:0002837)2.15296561
40Abnormality of glycolipid metabolism (HP:0010969)2.15142174
41Abnormality of liposaccharide metabolism (HP:0010968)2.15142174
42Abnormality of glycosphingolipid metabolism (HP:0004343)2.15142174
43Thoracic kyphosis (HP:0002942)2.14279549
44Achilles tendon contracture (HP:0001771)2.13959463
45Amaurosis fugax (HP:0100576)2.13937856
46Abnormality of polysaccharide metabolism (HP:0011012)2.13672479
47Abnormality of glycosaminoglycan metabolism (HP:0004371)2.13672479
48Abnormality of mucopolysaccharide metabolism (HP:0011020)2.13672479
49Reticulocytopenia (HP:0001896)2.13150351
50Premature rupture of membranes (HP:0001788)2.12892745
51Abnormality of T cells (HP:0002843)2.12215147
52Abnormality of monocarboxylic acid metabolism (HP:0010996)2.10364710
53Mediastinal lymphadenopathy (HP:0100721)2.06846126
54Abnormality of the astrocytes (HP:0100707)2.05750788
55Astrocytoma (HP:0009592)2.05750788
56Centrally nucleated skeletal muscle fibers (HP:0003687)2.05145376
57Abnormality of pyrimidine metabolism (HP:0004353)2.04129938
58Severe short stature (HP:0003510)2.04037941
59Pustule (HP:0200039)2.03491261
60T lymphocytopenia (HP:0005403)2.02853694
61Gingivitis (HP:0000230)2.02679622
62Disproportionate tall stature (HP:0001519)2.02355373
63Increased serum ferritin (HP:0003281)2.00235905
64Neuronal loss in central nervous system (HP:0002529)1.99668598
65Upper limb amyotrophy (HP:0009129)1.97767353
66Distal upper limb amyotrophy (HP:0007149)1.97767353
67Increased connective tissue (HP:0009025)1.97414551
68Ulnar bowing (HP:0003031)1.96923971
69Radial bowing (HP:0002986)1.96837540
70Chronic obstructive pulmonary disease (HP:0006510)1.96746172
71Obstructive lung disease (HP:0006536)1.96746172
72Fatigue (HP:0012378)1.96480282
73Polygenic inheritance (HP:0010982)1.94518242
74Inflammation of the large intestine (HP:0002037)1.92268216
75Autoimmune thrombocytopenia (HP:0001973)1.91965063
76Biconcave vertebral bodies (HP:0004586)1.91290865
77Stridor (HP:0010307)1.91036073
78Abnormality of the Achilles tendon (HP:0005109)1.90899640
79Spontaneous hematomas (HP:0007420)1.90518296
80Agammaglobulinemia (HP:0004432)1.90447246
81Abnormality of the common coagulation pathway (HP:0010990)1.90307257
82Meningitis (HP:0001287)1.90267159
83Abnormality of sulfur amino acid metabolism (HP:0004339)1.89417009
84Deep venous thrombosis (HP:0002625)1.88367009
85Hypertensive crisis (HP:0100735)1.87657363
86Poikiloderma (HP:0001029)1.84454279
87Increased density of long bones (HP:0006392)1.83561814
88Nuclear cataract (HP:0100018)1.83146831
89Multiple enchondromatosis (HP:0005701)1.82906762
90Elevated erythrocyte sedimentation rate (HP:0003565)1.82679403
91Distal lower limb muscle weakness (HP:0009053)1.82185362
92Abnormality of T cell number (HP:0011839)1.82101579
93Emphysema (HP:0002097)1.81628184
94Selective tooth agenesis (HP:0001592)1.80956240
95Abnormality of transition element cation homeostasis (HP:0011030)1.79917579
96Recurrent fungal infections (HP:0002841)1.79533439
97Abnormality of iron homeostasis (HP:0011031)1.79357259
98Papilloma (HP:0012740)1.78293584
99Verrucae (HP:0200043)1.78293584
100Cellulitis (HP:0100658)1.78115575
101Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.78064454
102Bowing of the arm (HP:0006488)1.77236768
103Bowed forearm bones (HP:0003956)1.77236768
104Cerebral inclusion bodies (HP:0100314)1.77185997
105Colitis (HP:0002583)1.77148610
106Premature skin wrinkling (HP:0100678)1.76650467
107Abnormality of cells of the lymphoid lineage (HP:0012140)1.76622472
108Hypertriglyceridemia (HP:0002155)1.74951662
109Metaphyseal cupping (HP:0003021)1.74356005
110Abnormality of reticulocytes (HP:0004312)1.73872851
111Abnormal gallbladder physiology (HP:0012438)1.73572876
112Cholecystitis (HP:0001082)1.73572876
113Systemic lupus erythematosus (HP:0002725)1.73381171
114Pallor (HP:0000980)1.73099916
115Genu recurvatum (HP:0002816)1.72042895
116Pseudobulbar signs (HP:0002200)1.71917719
117Easy fatigability (HP:0003388)1.71285010
118Entropion (HP:0000621)1.70998263
119Lymphopenia (HP:0001888)1.70238855
120Premature loss of primary teeth (HP:0006323)1.70101955
121Myositis (HP:0100614)1.70001792
122IgA deficiency (HP:0002720)1.69815475
123Supranuclear gaze palsy (HP:0000605)1.69557612
124Fragile skin (HP:0001030)1.69274500
125Insomnia (HP:0100785)1.69038912
126Birth length less than 3rd percentile (HP:0003561)1.68973357
127Agnosia (HP:0010524)1.68866913
128Rhabdomyosarcoma (HP:0002859)1.68822286
129Abnormal platelet function (HP:0011869)1.68699085
130Impaired platelet aggregation (HP:0003540)1.68699085
131Medulloblastoma (HP:0002885)1.68617087
132Bone pain (HP:0002653)1.67518681
133Malignant gastrointestinal tract tumors (HP:0006749)1.67457951
134Gastrointestinal carcinoma (HP:0002672)1.67457951
135Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.67257183
136Thin bony cortex (HP:0002753)1.67201028
137Interstitial pulmonary disease (HP:0006530)1.66857303
138Reticulocytosis (HP:0001923)1.66698950
139Abnormality of the calcaneus (HP:0008364)1.66485470
140Panhypogammaglobulinemia (HP:0003139)1.66035628
141Osteomyelitis (HP:0002754)1.65748046
142Deformed sella turcica (HP:0002681)1.65376168
143Abnormal delayed hypersensitivity skin test (HP:0002963)1.64704870
144Skin tags (HP:0010609)1.64602307
145Joint stiffness (HP:0001387)1.64221301
146Blue sclerae (HP:0000592)1.62929380
147Supernumerary nipples (HP:0002558)1.62757347
148Restrictive lung disease (HP:0002091)1.62359211
149Aneurysm (HP:0002617)1.61942590
150Adenoma sebaceum (HP:0009720)1.61319694
151Angiofibromas (HP:0010615)1.61319694
152Mitral regurgitation (HP:0001653)1.61234011
153Hematochezia (HP:0002573)1.61044566
154Epistaxis (HP:0000421)1.60969659
155Neoplasm of striated muscle (HP:0009728)1.60793156
156Slow saccadic eye movements (HP:0000514)1.60219201
157Abnormal platelet volume (HP:0011876)1.59354496
158Short 4th metacarpal (HP:0010044)1.59271380
159Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.59271380
160Abnormality of the thoracic spine (HP:0100711)1.59233358
161Vacuolated lymphocytes (HP:0001922)1.59190612
162Purpura (HP:0000979)1.59162611
163High pitched voice (HP:0001620)1.58633895
164Recurrent skin infections (HP:0001581)1.58610587
165Deep palmar crease (HP:0006191)1.58547696
166Micronodular cirrhosis (HP:0001413)1.58351183
167Recurrent gram-negative bacterial infections (HP:0005420)1.58309681
168Aplastic anemia (HP:0001915)1.57877469
169Overlapping toe (HP:0001845)1.57686077
170Lymphoma (HP:0002665)1.56330948
171Myocardial infarction (HP:0001658)1.55198575
172Cervical subluxation (HP:0003308)1.55190036
173Ureteral stenosis (HP:0000071)1.55162740
174Squamous cell carcinoma (HP:0002860)1.54683028
175Deviation of the thumb (HP:0009603)1.54153533

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K3.63581936
2SMG13.54624751
3PKN23.47005669
4MAP4K13.43381260
5PRPF4B3.31334433
6TRIB33.31277003
7ERN13.17305939
8MAP3K102.76215799
9CDK122.40171116
10FLT32.12921632
11PTK62.01334015
12SCYL21.97800187
13SIK11.93685508
14NEK21.85010258
15JAK31.84997570
16RPS6KB21.81839025
17ZAP701.79719957
18RIPK41.70113599
19TYK21.69000711
20MAP3K131.68144057
21CDC71.67803821
22PASK1.65516796
23STK101.61313110
24GRK61.58000820
25LRRK21.51710359
26EPHA21.48297669
27TESK21.46657637
28WEE11.45559586
29RPS6KA41.44058249
30BTK1.41036548
31TAOK21.40862612
32NME21.37540804
33FGFR41.37454417
34BCKDK1.34198699
35PAK41.33744876
36MAP2K31.31943386
37KIT1.31490848
38TTN1.28006764
39CDK41.23616332
40SIK31.21477805
41PRKD21.20074844
42MARK21.17420930
43CDC42BPA1.17241661
44MAP3K111.16263122
45ICK1.15398999
46MTOR1.13013681
47IRAK41.12245585
48MAP3K81.10927502
49ALK1.09393503
50MST1R1.08939311
51TNK21.07301348
52CDK71.05972845
53SIK21.01876281
54HIPK21.00109038
55TESK10.98020885
56CSF1R0.96119284
57TBK10.94459290
58TGFBR10.94054354
59ATR0.93591257
60MAP3K10.92000803
61KDR0.90039568
62PIM10.89107146
63PDGFRA0.87041927
64BUB10.86468373
65EIF2AK10.86360502
66BRD40.86311820
67ITK0.85140898
68JAK10.84139023
69TAOK30.82054933
70CDK60.81497633
71PDPK10.80710917
72RPS6KA20.80664807
73KSR20.79058430
74ARAF0.77713035
75MAPK110.76468661
76JAK20.75242524
77PIM20.75119891
78FES0.73835321
79RIPK10.73436593
80TSSK60.72195043
81PAK20.71301702
82MAP3K60.70709290
83LCK0.68112898
84MARK30.68038319
85BLK0.67008659
86CHUK0.66675001
87DYRK30.66504612
88MAPKAPK30.66312195
89PRKD30.66037286
90SYK0.64497321
91HCK0.63513481
92MAP2K20.62293818
93DDR20.60560322
94TYRO30.60505211
95CHEK10.59113367
96PDK10.58309386
97EPHB10.58108022
98CAMK1D0.57938420
99AURKB0.55537045
100CSK0.55481118
101LMTK20.55288713
102TAOK10.54309461
103IRAK20.53885335
104ACVR1B0.52440396
105TGFBR20.51956520
106MAP3K30.51599552
107MAPK120.51362887
108IKBKB0.51211617
109MAP3K70.50956566
110RET0.50100073
111CDK20.49852562
112IKBKE0.49681242
113EIF2AK30.49422485
114PTK20.48474472
115TXK0.47675167
116BMX0.44858458
117TTK0.44486829
118CDK90.43710699
119RPS6KA60.43623115
120CAMKK10.43434059
121BRAF0.43124797
122DYRK1B0.42758700
123MAPK70.42596516
124FGR0.42134250
125MAPKAPK20.40884129
126MATK0.40434483
127MAP3K140.40249324
128FGFR10.38963390
129PLK10.38349145
130FGFR30.38297426
131IRAK30.38095583
132ATM0.37752086
133STK40.37192429
134RPS6KA10.36232360
135PDGFRB0.35483096
136PRKCI0.34325755
137RPS6KC10.34004255
138RPS6KL10.34004255

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.04744461
2One carbon pool by folate_Homo sapiens_hsa006702.90474373
3Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.49899930
4Mismatch repair_Homo sapiens_hsa034302.35581797
5Selenocompound metabolism_Homo sapiens_hsa004501.97128374
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.87244086
7Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.86513497
8Primary immunodeficiency_Homo sapiens_hsa053401.82627038
9Spliceosome_Homo sapiens_hsa030401.79098879
10Base excision repair_Homo sapiens_hsa034101.70443458
11RNA transport_Homo sapiens_hsa030131.68218689
12Antigen processing and presentation_Homo sapiens_hsa046121.67814457
13Cyanoamino acid metabolism_Homo sapiens_hsa004601.66170383
14Lysine degradation_Homo sapiens_hsa003101.61412475
15Ribosome_Homo sapiens_hsa030101.60864342
16VEGF signaling pathway_Homo sapiens_hsa043701.52410156
17Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.46004195
18Acute myeloid leukemia_Homo sapiens_hsa052211.44689922
19B cell receptor signaling pathway_Homo sapiens_hsa046621.39530562
20Chronic myeloid leukemia_Homo sapiens_hsa052201.33850745
21Lysosome_Homo sapiens_hsa041421.33659491
22Biosynthesis of amino acids_Homo sapiens_hsa012301.26941981
23Prion diseases_Homo sapiens_hsa050201.25200265
24Herpes simplex infection_Homo sapiens_hsa051681.25042929
25Measles_Homo sapiens_hsa051621.23680503
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.20026739
27Tuberculosis_Homo sapiens_hsa051521.19044336
282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.19038155
29Nucleotide excision repair_Homo sapiens_hsa034201.16029504
30NF-kappa B signaling pathway_Homo sapiens_hsa040641.14742997
31Allograft rejection_Homo sapiens_hsa053301.14630176
32Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.12982655
33Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.12955995
34Cell cycle_Homo sapiens_hsa041101.12707734
35Small cell lung cancer_Homo sapiens_hsa052221.12309284
36Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.11426555
37Maturity onset diabetes of the young_Homo sapiens_hsa049501.10438879
38p53 signaling pathway_Homo sapiens_hsa041151.09379957
39AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.06758151
40Autoimmune thyroid disease_Homo sapiens_hsa053201.06550886
41Pentose phosphate pathway_Homo sapiens_hsa000301.05615973
42N-Glycan biosynthesis_Homo sapiens_hsa005101.02721727
43Graft-versus-host disease_Homo sapiens_hsa053321.01776910
44Pyrimidine metabolism_Homo sapiens_hsa002401.01628502
45Viral carcinogenesis_Homo sapiens_hsa052031.01522301
46Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.99777350
47Influenza A_Homo sapiens_hsa051640.96609298
48Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.96478332
49Legionellosis_Homo sapiens_hsa051340.96366175
50Primary bile acid biosynthesis_Homo sapiens_hsa001200.95991114
51Central carbon metabolism in cancer_Homo sapiens_hsa052300.95711134
52Apoptosis_Homo sapiens_hsa042100.95035625
53mRNA surveillance pathway_Homo sapiens_hsa030150.93140023
54Thyroid hormone signaling pathway_Homo sapiens_hsa049190.93135413
55Hepatitis B_Homo sapiens_hsa051610.90461407
56Leishmaniasis_Homo sapiens_hsa051400.90003565
57Sulfur relay system_Homo sapiens_hsa041220.89956530
58Non-small cell lung cancer_Homo sapiens_hsa052230.89351058
59mTOR signaling pathway_Homo sapiens_hsa041500.88566132
60Cysteine and methionine metabolism_Homo sapiens_hsa002700.88548219
61HTLV-I infection_Homo sapiens_hsa051660.88393445
62Notch signaling pathway_Homo sapiens_hsa043300.88280853
63Glioma_Homo sapiens_hsa052140.88153435
64Renal cell carcinoma_Homo sapiens_hsa052110.88025383
65T cell receptor signaling pathway_Homo sapiens_hsa046600.86943499
66Phospholipase D signaling pathway_Homo sapiens_hsa040720.86184093
67Thyroid cancer_Homo sapiens_hsa052160.85679564
68Arginine biosynthesis_Homo sapiens_hsa002200.84572756
69Fat digestion and absorption_Homo sapiens_hsa049750.84571306
70ErbB signaling pathway_Homo sapiens_hsa040120.83478975
71Insulin signaling pathway_Homo sapiens_hsa049100.83336021
72Homologous recombination_Homo sapiens_hsa034400.82873509
73Bladder cancer_Homo sapiens_hsa052190.82555305
74Intestinal immune network for IgA production_Homo sapiens_hsa046720.82498260
75Caffeine metabolism_Homo sapiens_hsa002320.81901119
76Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.81399331
77Galactose metabolism_Homo sapiens_hsa000520.80114854
78Insulin resistance_Homo sapiens_hsa049310.80099046
79Folate biosynthesis_Homo sapiens_hsa007900.80091334
80Other glycan degradation_Homo sapiens_hsa005110.80061148
81Toxoplasmosis_Homo sapiens_hsa051450.79999520
82Epstein-Barr virus infection_Homo sapiens_hsa051690.78457134
83Pertussis_Homo sapiens_hsa051330.77579544
84Fructose and mannose metabolism_Homo sapiens_hsa000510.77409548
85Amoebiasis_Homo sapiens_hsa051460.76585720
86Endocytosis_Homo sapiens_hsa041440.76524269
87Salmonella infection_Homo sapiens_hsa051320.75772143
88Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.75421323
89Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.75338419
90RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.75201945
91GnRH signaling pathway_Homo sapiens_hsa049120.74445870
92Chemokine signaling pathway_Homo sapiens_hsa040620.73518907
93MicroRNAs in cancer_Homo sapiens_hsa052060.73302693
94Choline metabolism in cancer_Homo sapiens_hsa052310.73258124
95Malaria_Homo sapiens_hsa051440.72829189
96Adipocytokine signaling pathway_Homo sapiens_hsa049200.72303638
97Sphingolipid signaling pathway_Homo sapiens_hsa040710.72293769
98Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.72292825
99Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.71829139
100Phosphatidylinositol signaling system_Homo sapiens_hsa040700.71264481
101Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69603641
102Osteoclast differentiation_Homo sapiens_hsa043800.69520063
103Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.66952259
104Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.66205034
105Shigellosis_Homo sapiens_hsa051310.65613701
106Colorectal cancer_Homo sapiens_hsa052100.65445324
107Inositol phosphate metabolism_Homo sapiens_hsa005620.63463032
108Focal adhesion_Homo sapiens_hsa045100.63360254
109Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.63130579
110Proteoglycans in cancer_Homo sapiens_hsa052050.62834560
111HIF-1 signaling pathway_Homo sapiens_hsa040660.62781994
112Pancreatic cancer_Homo sapiens_hsa052120.62668635
113Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.62569474
114Jak-STAT signaling pathway_Homo sapiens_hsa046300.62304099
115Hepatitis C_Homo sapiens_hsa051600.62085393
116Endometrial cancer_Homo sapiens_hsa052130.61631836
117Leukocyte transendothelial migration_Homo sapiens_hsa046700.60657983
118Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.60631313
119Estrogen signaling pathway_Homo sapiens_hsa049150.59815795
120RNA degradation_Homo sapiens_hsa030180.59319766
121Carbon metabolism_Homo sapiens_hsa012000.59120630
122NOD-like receptor signaling pathway_Homo sapiens_hsa046210.57872884
123Toll-like receptor signaling pathway_Homo sapiens_hsa046200.57639511
124Transcriptional misregulation in cancer_Homo sapiens_hsa052020.57381693
125ABC transporters_Homo sapiens_hsa020100.56652013
126Staphylococcus aureus infection_Homo sapiens_hsa051500.56327459
127Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.56271624
128Phagosome_Homo sapiens_hsa041450.56146072
129Viral myocarditis_Homo sapiens_hsa054160.54921116
130Glycosaminoglycan degradation_Homo sapiens_hsa005310.54692083
131Vibrio cholerae infection_Homo sapiens_hsa051100.54482714
132Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.54393736
133Prostate cancer_Homo sapiens_hsa052150.52194469
134Prolactin signaling pathway_Homo sapiens_hsa049170.50889655
135Systemic lupus erythematosus_Homo sapiens_hsa053220.50546376
136TNF signaling pathway_Homo sapiens_hsa046680.49286557
137Neurotrophin signaling pathway_Homo sapiens_hsa047220.49050874
138Hematopoietic cell lineage_Homo sapiens_hsa046400.48868563
139Nitrogen metabolism_Homo sapiens_hsa009100.48460434
140Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46986816

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