ATP2C2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.78255870
2epithelial cilium movement (GO:0003351)8.99071637
3oligosaccharide biosynthetic process (GO:0009312)8.57906160
4axoneme assembly (GO:0035082)6.76205482
5primary alcohol catabolic process (GO:0034310)6.44940283
6vitamin transmembrane transport (GO:0035461)6.23322623
7pyrimidine-containing compound transmembrane transport (GO:0072531)6.12743639
8pattern specification involved in kidney development (GO:0061004)6.03435030
9ethanol metabolic process (GO:0006067)6.02988655
10regulation of vascular endothelial growth factor signaling pathway (GO:1900746)5.94837859
11desmosome organization (GO:0002934)5.80569825
12fatty-acyl-CoA biosynthetic process (GO:0046949)5.78813142
13left/right pattern formation (GO:0060972)5.78226901
14long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)5.66021710
15acyl-CoA biosynthetic process (GO:0071616)5.63863103
16thioester biosynthetic process (GO:0035384)5.63863103
17ectoderm development (GO:0007398)5.57386449
18regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)5.31113024
19transcytosis (GO:0045056)5.28737321
20diterpenoid biosynthetic process (GO:0016102)5.26292195
21linoleic acid metabolic process (GO:0043651)5.25390703
22intestinal cholesterol absorption (GO:0030299)5.19950379
23hemidesmosome assembly (GO:0031581)4.98550880
24exocrine pancreas development (GO:0031017)4.97038223
25regulation of cilium movement (GO:0003352)4.94398125
26COPI coating of Golgi vesicle (GO:0048205)4.87340330
27Golgi transport vesicle coating (GO:0048200)4.87340330
28O-glycan processing (GO:0016266)4.87285629
29regulation of water loss via skin (GO:0033561)4.84279463
30long-chain fatty-acyl-CoA metabolic process (GO:0035336)4.77723869
31establishment of skin barrier (GO:0061436)4.71069260
32bundle of His cell to Purkinje myocyte communication (GO:0086069)4.67098647
33positive regulation of p38MAPK cascade (GO:1900745)4.66094676
34ventricular system development (GO:0021591)4.65814019
35left/right axis specification (GO:0070986)4.61817969
36ethanol oxidation (GO:0006069)4.60575323
37mammary gland epithelial cell differentiation (GO:0060644)4.57105232
38fatty-acyl-CoA metabolic process (GO:0035337)4.57071405
39alpha-linolenic acid metabolic process (GO:0036109)4.55118640
40intestinal epithelial cell development (GO:0060576)4.40709072
41lactation (GO:0007595)4.40682591
42N-acetylneuraminate metabolic process (GO:0006054)4.38796627
43hair cycle (GO:0042633)4.38370835
44molting cycle (GO:0042303)4.38370835
45keratinization (GO:0031424)4.37357724
46lung epithelium development (GO:0060428)4.36973797
47zinc ion transport (GO:0006829)4.30454971
48biotin metabolic process (GO:0006768)4.23368808
49establishment of apical/basal cell polarity (GO:0035089)4.23099421
50microtubule bundle formation (GO:0001578)4.22745601
51intestinal absorption (GO:0050892)4.22492091
52sperm capacitation (GO:0048240)4.19551545
53one-carbon compound transport (GO:0019755)4.18228247
54carnitine shuttle (GO:0006853)4.18185180
55copper ion transport (GO:0006825)4.14584610
56secretion by tissue (GO:0032941)4.12991418
57regulation of interleukin-5 production (GO:0032674)4.09454632
58regulation of interleukin-13 production (GO:0032656)4.08790014
59regulation of sequestering of triglyceride (GO:0010889)4.02292531
60protein retention in ER lumen (GO:0006621)3.98003639
61UDP-N-acetylglucosamine metabolic process (GO:0006047)3.97736472
62fatty acid transmembrane transport (GO:1902001)3.96304157
63citrulline biosynthetic process (GO:0019240)3.95442226
64regulation of apoptotic process involved in morphogenesis (GO:1902337)3.87699801
65negative regulation of T cell differentiation in thymus (GO:0033085)3.82341723
66phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.82237275
67maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.82135333
68intraciliary transport (GO:0042073)3.80982792
69interferon-gamma secretion (GO:0072643)3.77812182
70cilium organization (GO:0044782)3.72834594
71multicellular organismal water homeostasis (GO:0050891)3.64001137
72body fluid secretion (GO:0007589)3.63426676
73regulation of acrosome reaction (GO:0060046)3.63054755
74cilium assembly (GO:0042384)3.62614747
75establishment of monopolar cell polarity (GO:0061162)3.61878744
76establishment or maintenance of monopolar cell polarity (GO:0061339)3.61878744
77triglyceride biosynthetic process (GO:0019432)3.49659032
78neutral lipid biosynthetic process (GO:0046460)3.47950252
79acylglycerol biosynthetic process (GO:0046463)3.47950252
80keratinocyte differentiation (GO:0030216)3.46385835
81pentose-phosphate shunt (GO:0006098)3.45047939
82establishment of tissue polarity (GO:0007164)3.41381583
83establishment of planar polarity (GO:0001736)3.41381583
84folic acid transport (GO:0015884)3.40125361
85terpenoid biosynthetic process (GO:0016114)3.39326541
86tooth mineralization (GO:0034505)3.38732598
87nucleoside transmembrane transport (GO:1901642)3.38082010
88long-chain fatty acid transport (GO:0015909)3.33705081
89maintenance of gastrointestinal epithelium (GO:0030277)3.31422649
90digestion (GO:0007586)3.31391477
91glomerular epithelial cell development (GO:0072310)3.31165605
92digestive system process (GO:0022600)3.30683433
93positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003603.29565482
94negative regulation of keratinocyte proliferation (GO:0010839)3.29172891
95retinoic acid metabolic process (GO:0042573)3.28867642
96regulation of p38MAPK cascade (GO:1900744)3.27078098
97chemical homeostasis within a tissue (GO:0048875)3.27008976
98negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.25267667
99primary alcohol metabolic process (GO:0034308)3.24975455
100centriole assembly (GO:0098534)3.22944496
101striated muscle atrophy (GO:0014891)3.19665812
102positive regulation of respiratory burst (GO:0060267)3.18946820
103protein O-linked glycosylation (GO:0006493)3.17559982
104negative regulation of humoral immune response (GO:0002921)3.17229478
105segment specification (GO:0007379)3.17191889
106ear development (GO:0043583)3.16064225
107sodium ion homeostasis (GO:0055078)3.15219896
108positive regulation of sodium ion transmembrane transporter activity (GO:2000651)3.11219515
109antibacterial humoral response (GO:0019731)3.10904739
110acetyl-CoA metabolic process (GO:0006084)3.10827241
111embryonic process involved in female pregnancy (GO:0060136)3.10360200
112response to phenylpropanoid (GO:0080184)3.09230305
113water homeostasis (GO:0030104)3.08629430
114excretion (GO:0007588)3.07670598
115carnitine transmembrane transport (GO:1902603)3.05220514
116arachidonic acid secretion (GO:0050482)3.05054555
117icosanoid secretion (GO:0032309)3.05054555
118valine metabolic process (GO:0006573)3.05009215
119fatty acid transport (GO:0015908)3.03282820
120exogenous drug catabolic process (GO:0042738)3.00187680
121galactose metabolic process (GO:0006012)2.99250866
122microtubule-based movement (GO:0007018)2.98883076
123antimicrobial humoral response (GO:0019730)2.98259265
124cell projection assembly (GO:0030031)2.97579225
125surfactant homeostasis (GO:0043129)2.97416643
126sphingomyelin metabolic process (GO:0006684)2.97194891
127NADPH regeneration (GO:0006740)2.96817505
128decidualization (GO:0046697)2.96094258
129regulation of microtubule-based movement (GO:0060632)2.96086946
130calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.95900644
131apical protein localization (GO:0045176)2.94164545
132oligosaccharide metabolic process (GO:0009311)2.93815376
133nucleobase catabolic process (GO:0046113)2.93630158
134response to xenobiotic stimulus (GO:0009410)2.93514360
135fucose catabolic process (GO:0019317)2.92130248
136L-fucose metabolic process (GO:0042354)2.92130248
137L-fucose catabolic process (GO:0042355)2.92130248
138tight junction assembly (GO:0070830)2.90225303
139retinol metabolic process (GO:0042572)2.90153947
140positive regulation of epidermal cell differentiation (GO:0045606)2.89294633
141localization within membrane (GO:0051668)2.88179374
142carnitine transport (GO:0015879)2.87616111
143amino-acid betaine transport (GO:0015838)2.87616111
144glutathione biosynthetic process (GO:0006750)2.84962838
145regulation of female gonad development (GO:2000194)2.83393222
146cellular component assembly involved in morphogenesis (GO:0010927)2.83387867
147dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.82890962
148sphingosine metabolic process (GO:0006670)2.82619754
149protein localization to cilium (GO:0061512)2.81416305
150proline biosynthetic process (GO:0006561)2.80749572
151epoxygenase P450 pathway (GO:0019373)2.79675910
152COPII vesicle coating (GO:0048208)2.78971249
153iron ion import (GO:0097286)2.78689963
154regulation of triglyceride biosynthetic process (GO:0010866)2.78248866
155establishment or maintenance of apical/basal cell polarity (GO:0035088)2.77964834
156establishment or maintenance of bipolar cell polarity (GO:0061245)2.77964834
157retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.77832924
158carnitine metabolic process (GO:0009437)2.75376192
159asymmetric protein localization (GO:0008105)2.74698458
160renal absorption (GO:0070293)2.73892754
161skeletal muscle adaptation (GO:0043501)2.73788561
162phosphatidylcholine biosynthetic process (GO:0006656)2.73328652
163glutathione derivative metabolic process (GO:1901685)2.69136091
164glutathione derivative biosynthetic process (GO:1901687)2.69136091
165cytoplasmic microtubule organization (GO:0031122)2.68882530
166drug catabolic process (GO:0042737)2.64198730
167regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.62866790
168muscle atrophy (GO:0014889)2.61836946
169cilium morphogenesis (GO:0060271)2.61694289
170keratinocyte proliferation (GO:0043616)2.61278115
171regulation of autophagic vacuole assembly (GO:2000785)2.60366642
172negative regulation of inclusion body assembly (GO:0090084)2.58499903
173quaternary ammonium group transport (GO:0015697)2.57965139
174nonribosomal peptide biosynthetic process (GO:0019184)2.57910506
175epithelial cell-cell adhesion (GO:0090136)2.55159564
176negative regulation of B cell mediated immunity (GO:0002713)2.53836534
177negative regulation of immunoglobulin mediated immune response (GO:0002890)2.53836534
178positive regulation of smoothened signaling pathway (GO:0045880)2.53701697
179peptidyl-tyrosine autophosphorylation (GO:0038083)2.52209746
180sulfur compound transport (GO:0072348)2.51494103
181axonemal dynein complex assembly (GO:0070286)14.9291276
182cilium or flagellum-dependent cell motility (GO:0001539)12.4799951
183cilium movement (GO:0003341)10.7635634
184motile cilium assembly (GO:0044458)10.1680625

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human8.51408368
2STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse5.64835363
3* ESR1_21235772_ChIP-Seq_MCF-7_Human3.96737888
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.73439821
5* ESR2_21235772_ChIP-Seq_MCF-7_Human3.60697011
6DROSHA_22980978_ChIP-Seq_HELA_Human2.72090403
7ZNF263_19887448_ChIP-Seq_K562_Human2.60918871
8PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.54927714
9GATA4_25053715_ChIP-Seq_YYC3_Human2.53727152
10TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.53036522
11SOX2_27498859_Chip-Seq_STOMACH_Mouse2.52027924
12RARG_19884340_ChIP-ChIP_MEFs_Mouse2.39706076
13STAT6_21828071_ChIP-Seq_BEAS2B_Human2.39344688
14SOX2_20726797_ChIP-Seq_SW620_Human2.34849267
15CLOCK_20551151_ChIP-Seq_293T_Human2.30212418
16FOXO3_23340844_ChIP-Seq_DLD1_Human2.21167338
17TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.16829490
18P63_26484246_Chip-Seq_KERATINOCYTES_Human2.14668131
19ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.12601123
20SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.97619233
21GATA6_25053715_ChIP-Seq_YYC3_Human1.94145404
22SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.90280933
23RUNX1_27514584_Chip-Seq_MCF-7_Human1.89376703
24TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.86094396
25ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.83279035
26PPAR_26484153_Chip-Seq_NCI-H1993_Human1.82777781
27RACK7_27058665_Chip-Seq_MCF-7_Human1.82214656
28KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.77723750
29RXR_22158963_ChIP-Seq_LIVER_Mouse1.77329842
30PPARA_22158963_ChIP-Seq_LIVER_Mouse1.77281555
31KLF5_25053715_ChIP-Seq_YYC3_Human1.75549674
32* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.71459799
33CDX2_19796622_ChIP-Seq_MESCs_Mouse1.69133723
34TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.68935356
35* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.68361131
36SMC4_20622854_ChIP-Seq_HELA_Human1.68124856
37ARNT_22903824_ChIP-Seq_MCF-7_Human1.66944632
38LXR_22158963_ChIP-Seq_LIVER_Mouse1.62816337
39TRIM28_21343339_ChIP-Seq_HEK293_Human1.62716196
40CDX2_20551321_ChIP-Seq_CACO-2_Human1.61774804
41TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.61370324
42* ATF3_27146783_Chip-Seq_COLON_Human1.59729849
43SOX9_24532713_ChIP-Seq_HFSC_Mouse1.56669023
44STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.56107831
45* GATA3_24758297_ChIP-Seq_MCF-7_Human1.55316141
46CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.52935952
47ESR1_20079471_ChIP-ChIP_T-47D_Human1.49777939
48FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.47119828
49POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.42729207
50CTCF_27219007_Chip-Seq_Bcells_Human1.36436306
51KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.35653297
52FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.33355855
53SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.32703279
54SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.32703279
55ERG_21242973_ChIP-ChIP_JURKAT_Human1.32075328
56ESR1_15608294_ChIP-ChIP_MCF-7_Human1.31145610
57TDRD3_21172665_ChIP-Seq_MCF-7_Human1.30216064
58PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.29749931
59FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.25596588
60AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.25524622
61NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.25506474
62HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.24856736
63TP63_22573176_ChIP-Seq_HFKS_Human1.24419282
64ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.24170675
65NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.22493150
66CTNNB1_20460455_ChIP-Seq_HCT116_Human1.20919209
67STAT1_20625510_ChIP-Seq_HELA_Human1.17925494
68FOXA2_19822575_ChIP-Seq_HepG2_Human1.17578689
69PIAS1_25552417_ChIP-Seq_VCAP_Human1.17152970
70PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.16970564
71TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.16610081
72RAD21_21589869_ChIP-Seq_MESCs_Mouse1.15669711
73CHD1_26751641_Chip-Seq_LNCaP_Human1.14902227
74CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.13877553
75TP63_23658742_ChIP-Seq_EP156T_Human1.11831140
76HIF1A_21447827_ChIP-Seq_MCF-7_Human1.11719712
77EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.10999438
78RXR_22108803_ChIP-Seq_LS180_Human1.09453089
79FOXA1_25552417_ChIP-Seq_VCAP_Human1.05556274
80SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.05450889
81BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.05364928
82EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.04589268
83FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.02283698
84CEBPB_22108803_ChIP-Seq_LS180_Human1.02182701
85* LXR_22292898_ChIP-Seq_THP-1_Human1.00705682
86TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.00148884
87ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.95849986
88TBX20_22328084_ChIP-Seq_HEART_Mouse0.94172932
89TBX20_22080862_ChIP-Seq_HEART_Mouse0.94172932
90E2F1_20622854_ChIP-Seq_HELA_Human0.91782700
91BCOR_27268052_Chip-Seq_Bcells_Human0.91775759
92* CREB1_26743006_Chip-Seq_LNCaP_Human0.91505435
93EZH2_27294783_Chip-Seq_ESCs_Mouse0.90117057
94* PHF8_20622854_ChIP-Seq_HELA_Human0.89391354
95ELK3_25401928_ChIP-Seq_HUVEC_Human0.89361224
96* CTCF_20526341_ChIP-Seq_ESCs_Human0.88006799
97NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.87924259
98CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.87410820
99FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.87263700
100SA1_27219007_Chip-Seq_ERYTHROID_Human0.86908622
101JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.86573705
102ERG_20517297_ChIP-Seq_VCAP_Human0.85402502
103ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.85096349
104* FOXM1_26456572_ChIP-Seq_MCF-7_Human0.85050444
105MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.84705493
106BCL6_27268052_Chip-Seq_Bcells_Human0.83679281
107RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.83535056
108GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.82980870
109EP300_21415370_ChIP-Seq_HL-1_Mouse0.82595387
110ELF5_23300383_ChIP-Seq_T47D_Human0.82557538
111P300_27058665_Chip-Seq_ZR-75-30cells_Human0.82443432
112JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.81735185
113CJUN_26792858_Chip-Seq_BT549_Human0.81431935
114NR3C1_21868756_ChIP-Seq_MCF10A_Human0.81164371
115GATA2_21666600_ChIP-Seq_HMVEC_Human0.80450715
116AHR_22903824_ChIP-Seq_MCF-7_Human0.80284516
117GATA1_19941826_ChIP-Seq_K562_Human0.79897557
118P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.79174804
119TCF3_18692474_ChIP-Seq_MEFs_Mouse0.78495157
120GATA2_19941826_ChIP-Seq_K562_Human0.78107456
121BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.77872917
122FLI1_21867929_ChIP-Seq_CD8_Mouse0.77793715
123KDM2B_26808549_Chip-Seq_SUP-B15_Human0.77698628
124* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.77072486
125MYC_27129775_Chip-Seq_CORNEA_Mouse0.76813429
126PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.76532823
127RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.75633565
128SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.75368270
129P68_20966046_ChIP-Seq_HELA_Human0.74707571
130TCF4_18268006_ChIP-ChIP_LS174T_Human0.74364426
131* P53_21459846_ChIP-Seq_SAOS-2_Human0.74313420
132KDM2B_26808549_Chip-Seq_K562_Human0.73758780
133NANOG_18692474_ChIP-Seq_MEFs_Mouse0.72832235

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle7.62872825
2MP0001881_abnormal_mammary_gland7.56142490
3MP0002796_impaired_skin_barrier4.48529339
4MP0005083_abnormal_biliary_tract4.04040330
5MP0008875_abnormal_xenobiotic_pharmacok3.91150778
6MP0004043_abnormal_pH_regulation3.80315196
7MP0001666_abnormal_nutrient_absorption3.71259683
8MP0004264_abnormal_extraembryonic_tissu3.32093989
9MP0002653_abnormal_ependyma_morphology3.31515897
10MP0009780_abnormal_chondrocyte_physiolo3.31012074
11MP0000566_synostosis3.14807521
12MP0002254_reproductive_system_inflammat2.99454720
13MP0001873_stomach_inflammation2.96281184
14MP0003705_abnormal_hypodermis_morpholog2.93880667
15MP0002098_abnormal_vibrissa_morphology2.70582520
16MP0005501_abnormal_skin_physiology2.67860245
17MP0002132_abnormal_respiratory_system2.67740262
18MP0005275_abnormal_skin_tensile2.64493924
19MP0000678_abnormal_parathyroid_gland2.59444434
20MP0000627_abnormal_mammary_gland2.54521784
21MP0010678_abnormal_skin_adnexa2.46546067
22MP0005409_darkened_coat_color2.43529085
23MP0009379_abnormal_foot_pigmentation2.27503980
24MP0001664_abnormal_digestion2.18160144
25MP0003300_gastrointestinal_ulcer2.06374940
26MP0003718_maternal_effect2.01281549
27MP0000377_abnormal_hair_follicle1.95073950
28MP0004019_abnormal_vitamin_homeostasis1.93789499
29MP0006054_spinal_hemorrhage1.92451764
30MP0002249_abnormal_larynx_morphology1.82402308
31MP0001216_abnormal_epidermal_layer1.81250868
32MP0005085_abnormal_gallbladder_physiolo1.80479884
33MP0000579_abnormal_nail_morphology1.71349188
34MP0005451_abnormal_body_composition1.68612204
35MP0002060_abnormal_skin_morphology1.68122334
36MP0004947_skin_inflammation1.64634520
37MP0005220_abnormal_exocrine_pancreas1.63970015
38MP0003453_abnormal_keratinocyte_physiol1.62531437
39MP0004147_increased_porphyrin_level1.58478298
40MP0003878_abnormal_ear_physiology1.55476694
41MP0005377_hearing/vestibular/ear_phenot1.55476694
42MP0008789_abnormal_olfactory_epithelium1.49620266
43MP0010771_integument_phenotype1.47498774
44MP0000490_abnormal_crypts_of1.45951888
45MP0003303_peritoneal_inflammation1.42880191
46MP0001188_hyperpigmentation1.37704091
47MP0004185_abnormal_adipocyte_glucose1.37509343
48MP0001663_abnormal_digestive_system1.36889094
49MP0003011_delayed_dark_adaptation1.36659069
50MP0004133_heterotaxia1.34732830
51MP0001849_ear_inflammation1.33262621
52MP0000647_abnormal_sebaceous_gland1.31699571
53MP0003136_yellow_coat_color1.30064562
54MP0003566_abnormal_cell_adhesion1.28145782
55MP0002168_other_aberrant_phenotype1.27883064
56MP0000383_abnormal_hair_follicle1.27129736
57MP0004130_abnormal_muscle_cell1.25657610
58MP0003941_abnormal_skin_development1.25196759
59MP0010352_gastrointestinal_tract_polyps1.24775758
60MP0001984_abnormal_olfaction1.23882264
61MP0009384_cardiac_valve_regurgitation1.20776353
62MP0005381_digestive/alimentary_phenotyp1.19185788
63MP0002909_abnormal_adrenal_gland1.17040701
64MP0002160_abnormal_reproductive_system1.15646242
65MP0005365_abnormal_bile_salt1.15321983
66MP0005360_urolithiasis1.12676836
67MP0001485_abnormal_pinna_reflex1.10240065
68MP0005395_other_phenotype1.05990292
69MP0001765_abnormal_ion_homeostasis1.04170113
70MP0005666_abnormal_adipose_tissue1.03554460
71MP0003183_abnormal_peptide_metabolism1.03290652
72MP0008004_abnormal_stomach_pH1.02697230
73MP0002009_preneoplasia0.99734323
74MP0002118_abnormal_lipid_homeostasis0.99586487
75MP0009931_abnormal_skin_appearance0.98470561
76MP0002282_abnormal_trachea_morphology0.97242686
77MP0002822_catalepsy0.96744020
78MP0005636_abnormal_mineral_homeostasis0.95959491
79MP0000681_abnormal_thyroid_gland0.93887729
80MP0000427_abnormal_hair_cycle0.91560911
81MP0005394_taste/olfaction_phenotype0.89503757
82MP0005499_abnormal_olfactory_system0.89503757
83MP0002136_abnormal_kidney_physiology0.88567798
84MP0004782_abnormal_surfactant_physiolog0.88233188
85MP0000537_abnormal_urethra_morphology0.87128155
86MP0000462_abnormal_digestive_system0.84695322
87MP0002139_abnormal_hepatobiliary_system0.82816479
88MP0004272_abnormal_basement_membrane0.82356721
89MP0010386_abnormal_urinary_bladder0.81440748
90MP0009643_abnormal_urine_homeostasis0.80734570
91MP0005375_adipose_tissue_phenotype0.80539445
92MP0008438_abnormal_cutaneous_collagen0.79007821
93MP0000367_abnormal_coat/_hair0.77781954
94MP0000477_abnormal_intestine_morphology0.77448185
95MP0002876_abnormal_thyroid_physiology0.76943215
96MP0010329_abnormal_lipoprotein_level0.75853174
97MP0000538_abnormal_urinary_bladder0.75646531
98MP0004858_abnormal_nervous_system0.74334410
99MP0004381_abnormal_hair_follicle0.73113500
100MP0010155_abnormal_intestine_physiology0.71460889
101MP0000465_gastrointestinal_hemorrhage0.71455825
102MP0003866_abnormal_defecation0.71142623
103MP0005248_abnormal_Harderian_gland0.70853858
104MP0000467_abnormal_esophagus_morphology0.70155769
105MP0005023_abnormal_wound_healing0.69259290
106MP0000470_abnormal_stomach_morphology0.67935800
107MP0000762_abnormal_tongue_morphology0.67461986
108MP0002277_abnormal_respiratory_mucosa0.66810423
109MP0008872_abnormal_physiological_respon0.66673425
110MP0003936_abnormal_reproductive_system0.64407272
111MP0005670_abnormal_white_adipose0.63827947
112MP0005165_increased_susceptibility_to0.63642942
113MP0001191_abnormal_skin_condition0.62704071
114MP0003191_abnormal_cellular_cholesterol0.61753295
115MP0003045_fibrosis0.61311465
116MP0005408_hypopigmentation0.58392309
117MP0005076_abnormal_cell_differentiation0.57909413
118MP0010368_abnormal_lymphatic_system0.57281848
119MP0003879_abnormal_hair_cell0.57031274
120MP0001346_abnormal_lacrimal_gland0.56105196
121MP0000026_abnormal_inner_ear0.55820112
122MP0002896_abnormal_bone_mineralization0.55533868
123MP0003868_abnormal_feces_composition0.54116805
124MP0003950_abnormal_plasma_membrane0.52213663
125MP0005332_abnormal_amino_acid0.50070618
126MP0000609_abnormal_liver_physiology0.49561452
127MP0000613_abnormal_salivary_gland0.49033012
128MP0005310_abnormal_salivary_gland0.47869548
129MP0002693_abnormal_pancreas_physiology0.47746862
130MP0000003_abnormal_adipose_tissue0.47633851
131MP0001756_abnormal_urination0.46597337
132MP0001851_eye_inflammation0.42524767
133MP0001243_abnormal_dermal_layer0.42096994
134MP0003959_abnormal_lean_body0.41914575
135MP0005448_abnormal_energy_balance0.40008002
136MP0002970_abnormal_white_adipose0.39193457

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.80033457
2Abnormal respiratory epithelium morphology (HP:0012253)9.80033457
3Abnormal respiratory motile cilium physiology (HP:0012261)9.66187569
4Abnormal ciliary motility (HP:0012262)9.41934578
5Absent/shortened dynein arms (HP:0200106)9.39775505
6Dynein arm defect of respiratory motile cilia (HP:0012255)9.39775505
7Rhinitis (HP:0012384)8.95099610
8Bronchiectasis (HP:0002110)6.69844882
9Congenital ichthyosiform erythroderma (HP:0007431)6.50530424
10Right ventricular cardiomyopathy (HP:0011663)6.03032073
11Pili torti (HP:0003777)5.98288085
12Nasal polyposis (HP:0100582)5.97776737
13Abnormality of the nasal mucosa (HP:0000433)5.14519180
14Onycholysis (HP:0001806)4.87662403
15Gout (HP:0001997)4.59262118
16Amelogenesis imperfecta (HP:0000705)4.53521213
17Woolly hair (HP:0002224)4.42413349
18Congenital nonbullous ichthyosiform erythroderma (HP:0007479)4.36718951
19Abnormality of purine metabolism (HP:0004352)4.22442551
20Hypotrichosis (HP:0001006)4.15862450
21Infertility (HP:0000789)4.11119624
22Curly hair (HP:0002212)4.09077510
23Male infertility (HP:0003251)4.09061552
24Bronchitis (HP:0012387)4.05712992
25Milia (HP:0001056)3.95899350
26Ectropion (HP:0000656)3.89354545
27Fragile nails (HP:0001808)3.73408424
28Thin bony cortex (HP:0002753)3.70219422
29Abnormal hair laboratory examination (HP:0003328)3.69589741
30Chronic sinusitis (HP:0011109)3.50305362
31Decreased circulating renin level (HP:0003351)3.47780180
32Abnormality of nail color (HP:0100643)3.44644163
33Plantar hyperkeratosis (HP:0007556)3.44109570
34Recurrent sinusitis (HP:0011108)3.40255994
35Recurrent otitis media (HP:0000403)3.33565515
36Atrophic scars (HP:0001075)3.28394125
37Increased IgE level (HP:0003212)3.17496320
38Nail dystrophy (HP:0008404)3.15193693
39Pustule (HP:0200039)3.13953187
40Tubulointerstitial nephritis (HP:0001970)3.01092772
41Occipital encephalocele (HP:0002085)2.99329879
42Vacuolated lymphocytes (HP:0001922)2.94067968
43Atelectasis (HP:0100750)2.92441959
44Abnormality of renin-angiotensin system (HP:0000847)2.89319334
45Axonal loss (HP:0003447)2.89067548
46Abdominal distention (HP:0003270)2.86918820
47Hypoplasia of dental enamel (HP:0006297)2.82543036
48Hyperkalemia (HP:0002153)2.78441853
49Protuberant abdomen (HP:0001538)2.68700907
50Biliary tract neoplasm (HP:0100574)2.67451691
51Abnormality of chloride homeostasis (HP:0011422)2.66797061
52Dehydration (HP:0001944)2.66387628
53Aortic aneurysm (HP:0004942)2.64449860
54Glomerulosclerosis (HP:0000096)2.62993870
55Aortic dissection (HP:0002647)2.56337082
56Palmoplantar hyperkeratosis (HP:0000972)2.54390216
57Tubulointerstitial fibrosis (HP:0005576)2.54215785
58Erythroderma (HP:0001019)2.53889737
59Hyperaldosteronism (HP:0000859)2.53605617
60True hermaphroditism (HP:0010459)2.52893551
61Cystic liver disease (HP:0006706)2.51952293
62Stridor (HP:0010307)2.50772918
63Alopecia of scalp (HP:0002293)2.46335433
64Rectal prolapse (HP:0002035)2.44636023
65Arterial tortuosity (HP:0005116)2.44423757
66Subcapsular cataract (HP:0000523)2.41282775
67Chronic otitis media (HP:0000389)2.38495235
68Abnormality of nucleobase metabolism (HP:0010932)2.38029127
69Ileus (HP:0002595)2.36620822
70Conjunctival hamartoma (HP:0100780)2.36210605
71Renal salt wasting (HP:0000127)2.33129588
72Pancreatic fibrosis (HP:0100732)2.33064964
73Hypohidrosis (HP:0000966)2.31458539
74Steatorrhea (HP:0002570)2.29222388
75Palmar hyperkeratosis (HP:0010765)2.28925917
76Nephritis (HP:0000123)2.28813129
77Abnormality of renal excretion (HP:0011036)2.28514148
78Premature skin wrinkling (HP:0100678)2.22292179
79Cortical dysplasia (HP:0002539)2.16657987
80Enlarged epiphyses (HP:0010580)2.16298753
81Abnormality of small intestinal villus morphology (HP:0011472)2.14981782
82Villous atrophy (HP:0011473)2.14981782
83Corneal erosion (HP:0200020)2.14445653
84Bell-shaped thorax (HP:0001591)2.14418651
85Malnutrition (HP:0004395)2.13278049
86Vascular tortuosity (HP:0004948)2.11555538
87Hyperuricemia (HP:0002149)2.11254294
88Increased purine levels (HP:0004368)2.11254294
89Ventricular fibrillation (HP:0001663)2.10802038
90Vascular calcification (HP:0004934)2.10582207
91Abnormal blistering of the skin (HP:0008066)2.06331587
92Widely patent fontanelles and sutures (HP:0004492)2.05228998
93Fat malabsorption (HP:0002630)2.04481053
94Hyperparathyroidism (HP:0000843)2.03734167
95Tubular atrophy (HP:0000092)2.01577188
96Abnormality of the distal phalanges of the toes (HP:0010182)2.00210676
97Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.0332411
98Chronic bronchitis (HP:0004469)1.98734705
99Abnormality of calcium-phosphate metabolism (HP:0100530)1.97569626
100Brittle hair (HP:0002299)1.97107158
101Congenital, generalized hypertrichosis (HP:0004540)1.96129050
102Abnormality of monocarboxylic acid metabolism (HP:0010996)1.94889544
103Lip pit (HP:0100267)1.94549866
104Cardiovascular calcification (HP:0011915)1.94543389
105Premature loss of primary teeth (HP:0006323)1.91641519
106Hyponatremia (HP:0002902)1.90996462
107Overgrowth (HP:0001548)1.90115718
108Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.88873566
109Abnormality of the dental root (HP:0006486)1.88463894
110Taurodontia (HP:0000679)1.88463894
111Abnormality of permanent molar morphology (HP:0011071)1.88463894
112Molar tooth sign on MRI (HP:0002419)1.87981407
113Abnormality of midbrain morphology (HP:0002418)1.87981407
114Pancreatic cysts (HP:0001737)1.87811406
115Fragile skin (HP:0001030)1.87373269
116Fatigue (HP:0012378)1.86517010
117Nephronophthisis (HP:0000090)1.86494374
118Hyperactive renin-angiotensin system (HP:0000841)1.86007423
119Ankle contracture (HP:0006466)1.85123465
120Absent frontal sinuses (HP:0002688)1.83621727
121Lack of skin elasticity (HP:0100679)1.83469889
122Spinal cord compression (HP:0002176)1.83351675
123Sparse eyelashes (HP:0000653)1.82499700
124Abnormality of the dental pulp (HP:0006479)1.81702616
125Abnormality of transition element cation homeostasis (HP:0011030)1.81472861
126Abnormality of the costochondral junction (HP:0000919)1.80889942
127Chronic hepatic failure (HP:0100626)1.80381537
128Wide cranial sutures (HP:0010537)1.79818442
129Pruritus (HP:0000989)1.79226147
130Blepharitis (HP:0000498)1.78677832
131Abnormality of renal resorption (HP:0011038)1.75220458
132Abnormal biliary tract morphology (HP:0012440)1.74992111
133Postaxial foot polydactyly (HP:0001830)1.74923441
134Advanced eruption of teeth (HP:0006288)1.74878546
135Cone-rod dystrophy (HP:0000548)1.74018800
136Abnormality of molar (HP:0011077)1.73334400
137Abnormality of molar morphology (HP:0011070)1.73334400
138Palmoplantar keratoderma (HP:0000982)1.72751283
139Acanthosis nigricans (HP:0000956)1.68271900
140Cerebral aneurysm (HP:0004944)1.67162560
141Hyperglycinuria (HP:0003108)1.66566076
142Hyperglycinemia (HP:0002154)1.65735576
143Aneurysm (HP:0002617)1.64836303
144Furrowed tongue (HP:0000221)1.64351445
145Hyperphosphatemia (HP:0002905)1.64140508
146Flat acetabular roof (HP:0003180)1.62665554
147Abnormal hemoglobin (HP:0011902)1.62426381
148Congenital hepatic fibrosis (HP:0002612)1.56755755
149Abnormality of the renal medulla (HP:0100957)1.56484170
150Short nail (HP:0001799)1.56355723
151Male pseudohermaphroditism (HP:0000037)1.52410581
152Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.50829227
153Obstructive sleep apnea (HP:0002870)1.49150314
154Recurrent bronchitis (HP:0002837)1.48821974
155Bifid scrotum (HP:0000048)1.48543849
156Popliteal pterygium (HP:0009756)1.48108309
157Alkalosis (HP:0001948)1.46626313
158Aplasia/Hypoplasia of the tongue (HP:0010295)1.44842588
159Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.43680159
160Abnormal vertebral ossification (HP:0100569)1.41815178
161Hand muscle atrophy (HP:0009130)1.40874834
162Distal upper limb amyotrophy (HP:0007149)1.40249673
163Upper limb amyotrophy (HP:0009129)1.40249673
164Abnormality of glutamine family amino acid metabolism (HP:0010902)1.40109556
165Abnormality of sodium homeostasis (HP:0010931)1.39842365
166Aplasia of the musculature (HP:0100854)1.37499929
167Adrenal overactivity (HP:0002717)1.37379455
168Short thorax (HP:0010306)1.36476832
169Interstitial pulmonary disease (HP:0006530)1.35485352
170Abnormality of the frontal sinuses (HP:0002687)1.32081082
171Hemorrhage of the eye (HP:0011885)1.29795971
172Anencephaly (HP:0002323)1.29557341
173Distal lower limb muscle weakness (HP:0009053)1.28643644
174Nephropathy (HP:0000112)1.28283125
175Median cleft lip (HP:0000161)1.28013802
176Flattened epiphyses (HP:0003071)1.26309710
177Broad face (HP:0000283)1.25762082
178Aplasia/hypoplasia of the femur (HP:0005613)1.25658997
179Down-sloping shoulders (HP:0200021)1.24723968
180Short femoral neck (HP:0100864)1.23356450
181Abnormality of potassium homeostasis (HP:0011042)1.21049754

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK157.60513715
2PKN24.36189559
3EEF2K4.17294911
4SIK13.81588781
5TRIB33.64267964
6MAPKAPK33.60702982
7CAMK1D3.48251093
8ERN13.36589520
9BCKDK2.73767448
10LATS12.70124667
11CAMK1G2.38523462
12PTK62.29101818
13MST1R2.07881949
14EPHA22.00858489
15SMG12.00836892
16FRK1.97789028
17RPS6KB21.93924330
18LMTK21.92361438
19STK241.90601668
20MST41.88692427
21STK38L1.87519315
22FER1.87047596
23NME21.81777277
24RIPK11.69930533
25PIK3CA1.69454802
26LRRK21.67345523
27STK391.65590774
28MAP3K21.51419604
29PDK31.50551403
30PDK41.50551403
31MAP2K21.41095879
32ZAP701.40389958
33NEK61.40319320
34PDGFRB1.38739716
35TRPM71.33354709
36TGFBR21.32785492
37STK381.26159349
38PRKAA21.25947601
39MAP3K71.22498702
40PDK21.20291351
41ACVR1B1.18911771
42EPHB11.12355049
43MET1.09356036
44MAPKAPK51.07485702
45RET1.06419554
46PTK21.02576180
47BCR1.02420016
48PIK3CG1.01691413
49ICK1.00601534
50MARK20.98241705
51STK100.93949780
52TESK10.93096713
53FGFR40.89914758
54OXSR10.85318322
55DDR20.85313394
56GRK60.81955183
57MAP3K120.80491413
58KSR20.79556111
59MYLK0.79380071
60NME10.77825590
61MUSK0.77586437
62WNK40.71006495
63MAP3K30.68336558
64LATS20.67299457
65EPHB20.64623418
66STK30.64590023
67EPHA30.64076147
68MAP2K60.63893802
69BMX0.63094552
70PRKAA10.62618766
71TYRO30.62600224
72PAK20.62493014
73MAP2K10.62272979
74IRAK10.60668696
75PRKD20.59484240
76TAOK10.58361146
77PRKCI0.57346336
78TAOK30.55812733
79PTK2B0.55350203
80CSK0.54975748
81MATK0.54001964
82MAP3K80.53500560
83MAP3K90.49823220
84CHUK0.48581346
85PRKD30.48485195
86CDC42BPA0.48320544
87DAPK20.46491641
88PDGFRA0.46278428
89PNCK0.45990131
90TTK0.45623402
91ILK0.45441891
92IRAK30.43241515
93MAP3K10.42398198
94MTOR0.42351040
95MAPK110.40550214
96FLT30.39388010
97RPS6KA20.38359733
98TNK20.37501119
99AKT30.36257011
100TTN0.35883749
101HIPK20.35878929
102PDPK10.35298862
103CAMK2G0.34643994
104RPS6KB10.34361049
105MAP3K60.33974198
106PRKCZ0.32630726
107FGFR30.32581906
108PRKG20.32502573
109TBK10.31250647
110SCYL20.30920137
111MAP3K130.29226485
112ERBB20.29104503
113GSK3A0.28895140
114JAK20.28690159
115BRSK20.27251080
116PDK10.27063524
117MOS0.27009663
118CSNK1A10.26853045
119BRAF0.26811268
120PAK30.26642745
121PRKD10.26443539
122CAMKK10.26027489
123NUAK10.25689665
124IGF1R0.25349382
125CDK60.24894005
126GRK10.24595400
127ERBB40.24477630
128PAK40.24408891
129DMPK0.24050671
130RPS6KA10.23928240
131MAPK120.22787119
132EIF2AK30.22717476
133PRKCD0.21989161
134RPS6KC10.21667501
135RPS6KL10.21667501
136FGFR10.20935072
137MELK0.17493179
138SRC0.17409120
139ROCK10.17286956
140DYRK1B0.17192388
141RPS6KA60.17041052
142SGK10.16819815
143MAPKAPK20.16008646
144PRKCA0.15038344

Predicted pathways (KEGG)

RankGene SetZ-score
1Caffeine metabolism_Homo sapiens_hsa002327.68613945
2Fatty acid biosynthesis_Homo sapiens_hsa000617.13054170
3Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009803.73871492
4Phenylalanine metabolism_Homo sapiens_hsa003603.23390024
5Chemical carcinogenesis_Homo sapiens_hsa052043.15454876
6Drug metabolism - cytochrome P450_Homo sapiens_hsa009823.06861753
7Galactose metabolism_Homo sapiens_hsa000523.05006094
8Fat digestion and absorption_Homo sapiens_hsa049752.77215757
9Tyrosine metabolism_Homo sapiens_hsa003502.39540283
10Pancreatic secretion_Homo sapiens_hsa049722.25794508
11Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.18790803
12Propanoate metabolism_Homo sapiens_hsa006402.18008740
13Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.09272847
14Retinol metabolism_Homo sapiens_hsa008302.03380073
15Fatty acid metabolism_Homo sapiens_hsa012121.81253802
16Pyruvate metabolism_Homo sapiens_hsa006201.81069136
17Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.80926448
18Cyanoamino acid metabolism_Homo sapiens_hsa004601.74597425
19Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.67992529
20alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.66060306
21Protein digestion and absorption_Homo sapiens_hsa049741.64432355
22Mineral absorption_Homo sapiens_hsa049781.60337075
23Steroid hormone biosynthesis_Homo sapiens_hsa001401.59773096
24N-Glycan biosynthesis_Homo sapiens_hsa005101.52877509
25Folate biosynthesis_Homo sapiens_hsa007901.49227588
26Glycerolipid metabolism_Homo sapiens_hsa005611.45998884
27Prolactin signaling pathway_Homo sapiens_hsa049171.44934225
28Protein export_Homo sapiens_hsa030601.33164289
29Pentose and glucuronate interconversions_Homo sapiens_hsa000401.29181825
30Starch and sucrose metabolism_Homo sapiens_hsa005001.28031278
31Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.21334643
32Nitrogen metabolism_Homo sapiens_hsa009101.19495654
33Steroid biosynthesis_Homo sapiens_hsa001001.17885458
34Notch signaling pathway_Homo sapiens_hsa043301.17617443
35Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.17285464
36PPAR signaling pathway_Homo sapiens_hsa033201.17041805
37Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.15378121
38Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.14834511
39Linoleic acid metabolism_Homo sapiens_hsa005911.13502227
40Carbohydrate digestion and absorption_Homo sapiens_hsa049731.10681896
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.08457034
42Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.98561144
43Choline metabolism in cancer_Homo sapiens_hsa052310.98443771
44Tight junction_Homo sapiens_hsa045300.97623173
45Sulfur metabolism_Homo sapiens_hsa009200.88542333
46Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.84043560
47Fatty acid degradation_Homo sapiens_hsa000710.83895091
48Pentose phosphate pathway_Homo sapiens_hsa000300.81059655
492-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.78858831
50Other glycan degradation_Homo sapiens_hsa005110.76633580
51Fatty acid elongation_Homo sapiens_hsa000620.73395062
52Arachidonic acid metabolism_Homo sapiens_hsa005900.73284271
53Vibrio cholerae infection_Homo sapiens_hsa051100.71771013
54Ovarian steroidogenesis_Homo sapiens_hsa049130.70697839
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.70555156
56Vitamin digestion and absorption_Homo sapiens_hsa049770.70533795
57Sulfur relay system_Homo sapiens_hsa041220.68670829
58Renin-angiotensin system_Homo sapiens_hsa046140.67471670
59Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.67215410
60Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65205283
61Adherens junction_Homo sapiens_hsa045200.63200998
62AMPK signaling pathway_Homo sapiens_hsa041520.63006370
63Histidine metabolism_Homo sapiens_hsa003400.61655349
64Carbon metabolism_Homo sapiens_hsa012000.60769625
65VEGF signaling pathway_Homo sapiens_hsa043700.58567979
66Glutathione metabolism_Homo sapiens_hsa004800.58275399
67Bladder cancer_Homo sapiens_hsa052190.57551176
68Huntingtons disease_Homo sapiens_hsa050160.57430431
69Tryptophan metabolism_Homo sapiens_hsa003800.56509043
70Amoebiasis_Homo sapiens_hsa051460.56370400
71Insulin resistance_Homo sapiens_hsa049310.56367699
72Adipocytokine signaling pathway_Homo sapiens_hsa049200.55621918
73Phosphatidylinositol signaling system_Homo sapiens_hsa040700.54393134
74Hepatitis C_Homo sapiens_hsa051600.54324612
75ECM-receptor interaction_Homo sapiens_hsa045120.51854346
76Sphingolipid metabolism_Homo sapiens_hsa006000.51616359
77Pancreatic cancer_Homo sapiens_hsa052120.51118874
78Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.50252434
79Toxoplasmosis_Homo sapiens_hsa051450.50011532
80Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.47451736
81Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.47267516
82Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.47032221
83Bile secretion_Homo sapiens_hsa049760.46692674
84Gastric acid secretion_Homo sapiens_hsa049710.46600063
85Lysosome_Homo sapiens_hsa041420.43766957
86Arginine and proline metabolism_Homo sapiens_hsa003300.43037784
87Taste transduction_Homo sapiens_hsa047420.42818361
88Leukocyte transendothelial migration_Homo sapiens_hsa046700.42014245
89Fructose and mannose metabolism_Homo sapiens_hsa000510.39727751
90Estrogen signaling pathway_Homo sapiens_hsa049150.39368007
91Drug metabolism - other enzymes_Homo sapiens_hsa009830.39217839
92Biosynthesis of amino acids_Homo sapiens_hsa012300.38872621
93Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.38744634
94beta-Alanine metabolism_Homo sapiens_hsa004100.37913757
95Ether lipid metabolism_Homo sapiens_hsa005650.36976134
96Renin secretion_Homo sapiens_hsa049240.36900958
97Aldosterone synthesis and secretion_Homo sapiens_hsa049250.34666841
98mTOR signaling pathway_Homo sapiens_hsa041500.34303620
99Hippo signaling pathway_Homo sapiens_hsa043900.34282168
100Thyroid cancer_Homo sapiens_hsa052160.34220392
101Axon guidance_Homo sapiens_hsa043600.34157173
102Peroxisome_Homo sapiens_hsa041460.34072450
103Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.33881202
104Small cell lung cancer_Homo sapiens_hsa052220.33394820
105Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.32906783
106GnRH signaling pathway_Homo sapiens_hsa049120.32884062
107Maturity onset diabetes of the young_Homo sapiens_hsa049500.32722632
108Glycerophospholipid metabolism_Homo sapiens_hsa005640.32282823
109Endometrial cancer_Homo sapiens_hsa052130.30921711
110Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.29482614
111Influenza A_Homo sapiens_hsa051640.26943998
112Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.26406627
113Insulin signaling pathway_Homo sapiens_hsa049100.25960268
114Inositol phosphate metabolism_Homo sapiens_hsa005620.25738362
115Vascular smooth muscle contraction_Homo sapiens_hsa042700.25647127
116Cocaine addiction_Homo sapiens_hsa050300.25188976
117Thyroid hormone synthesis_Homo sapiens_hsa049180.25020448
118Prostate cancer_Homo sapiens_hsa052150.24570513
119Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.24270929
120Collecting duct acid secretion_Homo sapiens_hsa049660.23603815
121Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.23356027
122Proteoglycans in cancer_Homo sapiens_hsa052050.22924105
123Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.22899786
124Metabolic pathways_Homo sapiens_hsa011000.22586496
125Chronic myeloid leukemia_Homo sapiens_hsa052200.22456268
126Circadian rhythm_Homo sapiens_hsa047100.20995750
127Arginine biosynthesis_Homo sapiens_hsa002200.20531853
128AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.20342176
129Sphingolipid signaling pathway_Homo sapiens_hsa040710.19332576
130Acute myeloid leukemia_Homo sapiens_hsa052210.19028586
131Endocytosis_Homo sapiens_hsa041440.18941747
132ABC transporters_Homo sapiens_hsa020100.18902709
133Focal adhesion_Homo sapiens_hsa045100.17451824
134Salivary secretion_Homo sapiens_hsa049700.16415381
135Longevity regulating pathway - mammal_Homo sapiens_hsa042110.14624592

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