

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | tooth mineralization (GO:0034505) | 9.84462318 |
| 2 | positive regulation of protein sumoylation (GO:0033235) | 8.62803113 |
| 3 | negative regulation of T-helper cell differentiation (GO:0045623) | 8.25211807 |
| 4 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 8.25211807 |
| 5 | protein K11-linked deubiquitination (GO:0035871) | 8.18888064 |
| 6 | seminiferous tubule development (GO:0072520) | 7.75241865 |
| 7 | regulation of T-helper 1 cell differentiation (GO:0045625) | 7.39310133 |
| 8 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 7.19027371 |
| 9 | positive regulation of RNA splicing (GO:0033120) | 7.17051108 |
| 10 | regulation of T-helper 2 cell differentiation (GO:0045628) | 7.14869931 |
| 11 | negative regulation of type 2 immune response (GO:0002829) | 7.00228575 |
| 12 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 6.86955080 |
| 13 | activation of protein kinase A activity (GO:0034199) | 6.56082712 |
| 14 | positive regulation of mitochondrial fission (GO:0090141) | 6.27091212 |
| 15 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 6.20499699 |
| 16 | righting reflex (GO:0060013) | 5.85625498 |
| 17 | cAMP biosynthetic process (GO:0006171) | 5.74069508 |
| 18 | enteric nervous system development (GO:0048484) | 5.69699747 |
| 19 | synaptic transmission, dopaminergic (GO:0001963) | 5.60220975 |
| 20 | dendritic spine morphogenesis (GO:0060997) | 5.58902225 |
| 21 | regulation of protein sumoylation (GO:0033233) | 5.52132841 |
| 22 | icosanoid secretion (GO:0032309) | 5.40069191 |
| 23 | arachidonic acid secretion (GO:0050482) | 5.40069191 |
| 24 | positive regulation of T-helper 1 type immune response (GO:0002827) | 5.38295644 |
| 25 | detection of chemical stimulus (GO:0009593) | 5.18074735 |
| 26 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 5.11009973 |
| 27 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.78181493 |
| 28 | ATP synthesis coupled proton transport (GO:0015986) | 4.78181493 |
| 29 | regulation of mitochondrial fission (GO:0090140) | 4.67140595 |
| 30 | heterotypic cell-cell adhesion (GO:0034113) | 4.65235072 |
| 31 | positive regulation of T-helper cell differentiation (GO:0045624) | 4.60453511 |
| 32 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 4.60232466 |
| 33 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.51114191 |
| 34 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.46285238 |
| 35 | hepatocyte apoptotic process (GO:0097284) | 4.42309013 |
| 36 | fatty acid derivative transport (GO:1901571) | 4.35141036 |
| 37 | icosanoid transport (GO:0071715) | 4.35141036 |
| 38 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.32964531 |
| 39 | cellular response to ATP (GO:0071318) | 4.23887111 |
| 40 | neural tube formation (GO:0001841) | 4.19501874 |
| 41 | DNA deamination (GO:0045006) | 4.06754114 |
| 42 | drug transmembrane transport (GO:0006855) | 4.01169025 |
| 43 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 3.99014992 |
| 44 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.97076915 |
| 45 | ATP hydrolysis coupled proton transport (GO:0015991) | 3.93363235 |
| 46 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 3.93363235 |
| 47 | endothelial cell differentiation (GO:0045446) | 3.93197965 |
| 48 | negative regulation of alpha-beta T cell activation (GO:0046636) | 3.91914784 |
| 49 | regulation of T-helper 1 type immune response (GO:0002825) | 3.86278611 |
| 50 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.79502185 |
| 51 | embryonic digestive tract morphogenesis (GO:0048557) | 3.71553394 |
| 52 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 3.67406654 |
| 53 | chemosensory behavior (GO:0007635) | 3.61752574 |
| 54 | monoamine transport (GO:0015844) | 3.57810386 |
| 55 | retina layer formation (GO:0010842) | 3.51616061 |
| 56 | reflex (GO:0060004) | 3.46537509 |
| 57 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 3.46071840 |
| 58 | neuronal ion channel clustering (GO:0045161) | 3.45359417 |
| 59 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.42895547 |
| 60 | regulation of T-helper cell differentiation (GO:0045622) | 3.42386316 |
| 61 | nephron epithelium morphogenesis (GO:0072088) | 3.38609037 |
| 62 | nephron tubule morphogenesis (GO:0072078) | 3.38609037 |
| 63 | protein localization to synapse (GO:0035418) | 3.35623308 |
| 64 | positive regulation of membrane potential (GO:0045838) | 3.34467981 |
| 65 | cytidine deamination (GO:0009972) | 3.33816223 |
| 66 | cytidine metabolic process (GO:0046087) | 3.33816223 |
| 67 | cytidine catabolic process (GO:0006216) | 3.33816223 |
| 68 | negative regulation of T cell differentiation (GO:0045581) | 3.27528622 |
| 69 | vocalization behavior (GO:0071625) | 3.27152344 |
| 70 | water transport (GO:0006833) | 3.20633139 |
| 71 | regulation of cAMP-mediated signaling (GO:0043949) | 3.12009614 |
| 72 | detection of light stimulus involved in visual perception (GO:0050908) | 3.10341194 |
| 73 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.10341194 |
| 74 | chaperone-mediated protein transport (GO:0072321) | 3.09962818 |
| 75 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 3.01429357 |
| 76 | cyclic purine nucleotide metabolic process (GO:0052652) | 2.97856149 |
| 77 | negative regulation of astrocyte differentiation (GO:0048712) | 2.97458800 |
| 78 | neuromuscular process controlling posture (GO:0050884) | 2.96371331 |
| 79 | left/right axis specification (GO:0070986) | 2.95405668 |
| 80 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.94390071 |
| 81 | regulation of type 2 immune response (GO:0002828) | 2.94144807 |
| 82 | fluid transport (GO:0042044) | 2.93347391 |
| 83 | cyclic nucleotide biosynthetic process (GO:0009190) | 2.90767146 |
| 84 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.88336130 |
| 85 | response to dietary excess (GO:0002021) | 2.85751353 |
| 86 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 2.85061895 |
| 87 | negative regulation of actin filament bundle assembly (GO:0032232) | 2.85015179 |
| 88 | single fertilization (GO:0007338) | 2.81254417 |
| 89 | response to nicotine (GO:0035094) | 2.71550991 |
| 90 | cAMP metabolic process (GO:0046058) | 2.70498209 |
| 91 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (GO:0007193) | 2.69627402 |
| 92 | potassium ion transmembrane transport (GO:0071805) | 2.67943780 |
| 93 | cellular potassium ion transport (GO:0071804) | 2.67943780 |
| 94 | cellular response to glucagon stimulus (GO:0071377) | 2.67909522 |
| 95 | positive thymic T cell selection (GO:0045059) | 2.67499428 |
| 96 | dendritic spine organization (GO:0097061) | 2.66661925 |
| 97 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.64889706 |
| 98 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.64847726 |
| 99 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 2.62735116 |
| 100 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 11.2865227 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 8.91766292 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 5.38376834 |
| 3 | IGF1R_20145208_ChIP-Seq_DFB_Human | 4.48652792 |
| 4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 4.08467886 |
| 5 | AR_21572438_ChIP-Seq_LNCaP_Human | 3.38521453 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.60082417 |
| 7 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.50333298 |
| 8 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.29575357 |
| 9 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.28666982 |
| 10 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.08798122 |
| 11 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 2.05178501 |
| 12 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.92727912 |
| 13 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.83423174 |
| 14 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.78756634 |
| 15 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.78436703 |
| 16 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.73067238 |
| 17 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.69009526 |
| 18 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.67996006 |
| 19 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.67996006 |
| 20 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.61306864 |
| 21 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.60339376 |
| 22 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.58449779 |
| 23 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.57283897 |
| 24 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.55806740 |
| 25 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.49237225 |
| 26 | FUS_26573619_Chip-Seq_HEK293_Human | 1.47342073 |
| 27 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.43904843 |
| 28 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.41785287 |
| 29 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.40953583 |
| 30 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.40953583 |
| 31 | EWS_26573619_Chip-Seq_HEK293_Human | 1.40456260 |
| 32 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.40426591 |
| 33 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.40023809 |
| 34 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.35270055 |
| 35 | P300_19829295_ChIP-Seq_ESCs_Human | 1.34528465 |
| 36 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.31969755 |
| 37 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.31454938 |
| 38 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.31225729 |
| 39 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.30016325 |
| 40 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.29224492 |
| 41 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.28854614 |
| 42 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.28578573 |
| 43 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.28154482 |
| 44 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.27840021 |
| 45 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.27196345 |
| 46 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.25288541 |
| 47 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.25046352 |
| 48 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.24592713 |
| 49 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.24406190 |
| 50 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.24406190 |
| 51 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.23503506 |
| 52 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.23315797 |
| 53 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.23157801 |
| 54 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.22801100 |
| 55 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.20784474 |
| 56 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.19991839 |
| 57 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.18804932 |
| 58 | TP53_16413492_ChIP-PET_HCT116_Human | 1.18724126 |
| 59 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.18572270 |
| 60 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.18503311 |
| 61 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.18067141 |
| 62 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.17151649 |
| 63 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.16979088 |
| 64 | STAT3_23295773_ChIP-Seq_U87_Human | 1.16335882 |
| 65 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.15872881 |
| 66 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.15651716 |
| 67 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.15175546 |
| 68 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.14628809 |
| 69 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.14628809 |
| 70 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.14354045 |
| 71 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.14185372 |
| 72 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.13252246 |
| 73 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.12891716 |
| 74 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.12791895 |
| 75 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.12537785 |
| 76 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.12532761 |
| 77 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.12425024 |
| 78 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.12045909 |
| 79 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.11778199 |
| 80 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.10368701 |
| 81 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.09274391 |
| 82 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.07931174 |
| 83 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.07431714 |
| 84 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.06247831 |
| 85 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.04837393 |
| 86 | AR_25329375_ChIP-Seq_VCAP_Human | 1.04514263 |
| 87 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.03928076 |
| 88 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.02459415 |
| 89 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.01241474 |
| 90 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.00824063 |
| 91 | TBL1_22424771_ChIP-Seq_293T_Human | 1.00804068 |
| 92 | NCOR_22424771_ChIP-Seq_293T_Human | 0.99942823 |
| 93 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.99800125 |
| 94 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.99134932 |
| 95 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.99087331 |
| 96 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.98912989 |
| 97 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.98223128 |
| 98 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.97691261 |
| 99 | NFYB_21822215_ChIP-Seq_K562_Human | 0.95675568 |
| 100 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.94119113 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005084_abnormal_gallbladder_morpholo | 9.89452630 |
| 2 | MP0008961_abnormal_basal_metabolism | 7.17647910 |
| 3 | MP0006072_abnormal_retinal_apoptosis | 3.05175001 |
| 4 | MP0004130_abnormal_muscle_cell | 2.85569105 |
| 5 | MP0003252_abnormal_bile_duct | 2.78663388 |
| 6 | MP0004133_heterotaxia | 2.48250762 |
| 7 | MP0005646_abnormal_pituitary_gland | 2.15736919 |
| 8 | MP0002928_abnormal_bile_duct | 2.11793007 |
| 9 | MP0002751_abnormal_autonomic_nervous | 2.09865991 |
| 10 | MP0003880_abnormal_central_pattern | 2.08363274 |
| 11 | MP0005379_endocrine/exocrine_gland_phen | 2.02418628 |
| 12 | MP0004264_abnormal_extraembryonic_tissu | 1.97405125 |
| 13 | MP0002102_abnormal_ear_morphology | 1.81343508 |
| 14 | MP0005448_abnormal_energy_balance | 1.79770455 |
| 15 | MP0005671_abnormal_response_to | 1.78653710 |
| 16 | MP0001968_abnormal_touch/_nociception | 1.77929908 |
| 17 | MP0002837_dystrophic_cardiac_calcinosis | 1.69029597 |
| 18 | MP0002736_abnormal_nociception_after | 1.59395889 |
| 19 | MP0003943_abnormal_hepatobiliary_system | 1.47816981 |
| 20 | MP0003195_calcinosis | 1.46371062 |
| 21 | MP0003718_maternal_effect | 1.38779743 |
| 22 | MP0005253_abnormal_eye_physiology | 1.35154564 |
| 23 | MP0009764_decreased_sensitivity_to | 1.32874373 |
| 24 | MP0001835_abnormal_antigen_presentation | 1.32740489 |
| 25 | MP0005220_abnormal_exocrine_pancreas | 1.32486019 |
| 26 | MP0008875_abnormal_xenobiotic_pharmacok | 1.31608563 |
| 27 | MP0005551_abnormal_eye_electrophysiolog | 1.29879029 |
| 28 | MP0001905_abnormal_dopamine_level | 1.29414175 |
| 29 | MP0001270_distended_abdomen | 1.23042928 |
| 30 | MP0004147_increased_porphyrin_level | 1.21965171 |
| 31 | MP0008872_abnormal_physiological_respon | 1.20027049 |
| 32 | MP0001800_abnormal_humoral_immune | 1.19721006 |
| 33 | MP0002909_abnormal_adrenal_gland | 1.17610489 |
| 34 | MP0002572_abnormal_emotion/affect_behav | 1.10727411 |
| 35 | MP0005408_hypopigmentation | 1.10275202 |
| 36 | MP0001529_abnormal_vocalization | 1.07728240 |
| 37 | MP0006276_abnormal_autonomic_nervous | 1.06701617 |
| 38 | MP0000372_irregular_coat_pigmentation | 1.05006530 |
| 39 | MP0002693_abnormal_pancreas_physiology | 1.04680204 |
| 40 | MP0002277_abnormal_respiratory_mucosa | 1.01909002 |
| 41 | MP0002405_respiratory_system_inflammati | 0.99460418 |
| 42 | MP0003866_abnormal_defecation | 0.95657385 |
| 43 | MP0003646_muscle_fatigue | 0.95135491 |
| 44 | MP0005423_abnormal_somatic_nervous | 0.94978654 |
| 45 | MP0000465_gastrointestinal_hemorrhage | 0.94526626 |
| 46 | MP0002138_abnormal_hepatobiliary_system | 0.93508321 |
| 47 | MP0009785_altered_susceptibility_to | 0.90607627 |
| 48 | MP0008877_abnormal_DNA_methylation | 0.90505712 |
| 49 | MP0000470_abnormal_stomach_morphology | 0.90079454 |
| 50 | MP0004145_abnormal_muscle_electrophysio | 0.89877033 |
| 51 | MP0001944_abnormal_pancreas_morphology | 0.87716527 |
| 52 | MP0002163_abnormal_gland_morphology | 0.87122911 |
| 53 | MP0009046_muscle_twitch | 0.86821799 |
| 54 | MP0001790_abnormal_immune_system | 0.85372400 |
| 55 | MP0005387_immune_system_phenotype | 0.85372400 |
| 56 | MP0005000_abnormal_immune_tolerance | 0.85171097 |
| 57 | MP0001486_abnormal_startle_reflex | 0.84956031 |
| 58 | MP0002148_abnormal_hypersensitivity_rea | 0.84783515 |
| 59 | MP0001986_abnormal_taste_sensitivity | 0.83806124 |
| 60 | MP0008469_abnormal_protein_level | 0.81745309 |
| 61 | MP0002234_abnormal_pharynx_morphology | 0.80985783 |
| 62 | MP0001485_abnormal_pinna_reflex | 0.80874669 |
| 63 | MP0002723_abnormal_immune_serum | 0.79591593 |
| 64 | MP0005360_urolithiasis | 0.79417554 |
| 65 | MP0005332_abnormal_amino_acid | 0.79060283 |
| 66 | MP0009745_abnormal_behavioral_response | 0.77524988 |
| 67 | MP0006292_abnormal_olfactory_placode | 0.76715788 |
| 68 | MP0003638_abnormal_response/metabolism_ | 0.75416414 |
| 69 | MP0002136_abnormal_kidney_physiology | 0.74855309 |
| 70 | MP0001845_abnormal_inflammatory_respons | 0.74776929 |
| 71 | MP0001501_abnormal_sleep_pattern | 0.73326218 |
| 72 | MP0004019_abnormal_vitamin_homeostasis | 0.73197739 |
| 73 | MP0005377_hearing/vestibular/ear_phenot | 0.72560546 |
| 74 | MP0003878_abnormal_ear_physiology | 0.72560546 |
| 75 | MP0000604_amyloidosis | 0.72030083 |
| 76 | MP0002420_abnormal_adaptive_immunity | 0.71952913 |
| 77 | MP0002452_abnormal_antigen_presenting | 0.71604173 |
| 78 | MP0001819_abnormal_immune_cell | 0.71132592 |
| 79 | MP0000703_abnormal_thymus_morphology | 0.70206608 |
| 80 | MP0004742_abnormal_vestibular_system | 0.70117241 |
| 81 | MP0003786_premature_aging | 0.69275903 |
| 82 | MP0009333_abnormal_splenocyte_physiolog | 0.69195859 |
| 83 | MP0002272_abnormal_nervous_system | 0.69043601 |
| 84 | MP0005410_abnormal_fertilization | 0.66405687 |
| 85 | MP0002822_catalepsy | 0.65737179 |
| 86 | MP0003763_abnormal_thymus_physiology | 0.63750172 |
| 87 | MP0005165_increased_susceptibility_to | 0.63341382 |
| 88 | MP0002735_abnormal_chemical_nociception | 0.62715470 |
| 89 | MP0005645_abnormal_hypothalamus_physiol | 0.60371668 |
| 90 | MP0002098_abnormal_vibrissa_morphology | 0.59239880 |
| 91 | MP0003953_abnormal_hormone_level | 0.58322745 |
| 92 | MP0000716_abnormal_immune_system | 0.57105535 |
| 93 | MP0002398_abnormal_bone_marrow | 0.56783475 |
| 94 | MP0003724_increased_susceptibility_to | 0.56562842 |
| 95 | MP0002733_abnormal_thermal_nociception | 0.55806051 |
| 96 | MP0001970_abnormal_pain_threshold | 0.55697550 |
| 97 | MP0003137_abnormal_impulse_conducting | 0.55174132 |
| 98 | MP0002078_abnormal_glucose_homeostasis | 0.55142239 |
| 99 | MP0003635_abnormal_synaptic_transmissio | 0.54890160 |
| 100 | MP0001919_abnormal_reproductive_system | 0.54879040 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Amelogenesis imperfecta (HP:0000705) | 7.37431753 |
| 2 | Overgrowth (HP:0001548) | 6.33989572 |
| 3 | Abnormality of renal resorption (HP:0011038) | 6.22782949 |
| 4 | Abnormality of dental color (HP:0011073) | 5.73489232 |
| 5 | Polyuria (HP:0000103) | 5.72037244 |
| 6 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 5.70476674 |
| 7 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 5.00497430 |
| 8 | Abnormal urine output (HP:0012590) | 4.82433330 |
| 9 | Osteomalacia (HP:0002749) | 4.79149893 |
| 10 | Abnormality of renal excretion (HP:0011036) | 4.29370978 |
| 11 | Abnormality of the dental pulp (HP:0006479) | 3.99413299 |
| 12 | Abnormality of midbrain morphology (HP:0002418) | 3.73289544 |
| 13 | Molar tooth sign on MRI (HP:0002419) | 3.73289544 |
| 14 | Chronic bronchitis (HP:0004469) | 3.38866185 |
| 15 | Nephronophthisis (HP:0000090) | 3.38184491 |
| 16 | Inability to walk (HP:0002540) | 3.35619154 |
| 17 | Volvulus (HP:0002580) | 3.28580724 |
| 18 | IgM deficiency (HP:0002850) | 3.27684566 |
| 19 | Abnormality of urine glucose concentration (HP:0011016) | 3.16358382 |
| 20 | Glycosuria (HP:0003076) | 3.16358382 |
| 21 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.14225572 |
| 22 | Hyperphosphaturia (HP:0003109) | 3.02211589 |
| 23 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.88993986 |
| 24 | Round ear (HP:0100830) | 2.86777749 |
| 25 | Abnormality of the renal medulla (HP:0100957) | 2.80271271 |
| 26 | Congenital stationary night blindness (HP:0007642) | 2.75500259 |
| 27 | Rhinitis (HP:0012384) | 2.72949601 |
| 28 | Tachypnea (HP:0002789) | 2.68165844 |
| 29 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.62141192 |
| 30 | Autoimmune thrombocytopenia (HP:0001973) | 2.61110627 |
| 31 | Panhypogammaglobulinemia (HP:0003139) | 2.53379988 |
| 32 | Degeneration of anterior horn cells (HP:0002398) | 2.49814910 |
| 33 | Abnormality of the anterior horn cell (HP:0006802) | 2.49814910 |
| 34 | Aplastic anemia (HP:0001915) | 2.48915896 |
| 35 | Abnormal urine phosphate concentration (HP:0012599) | 2.44244842 |
| 36 | Toxemia of pregnancy (HP:0100603) | 2.40207596 |
| 37 | True hermaphroditism (HP:0010459) | 2.32027811 |
| 38 | Mitochondrial inheritance (HP:0001427) | 2.24917153 |
| 39 | Prominent supraorbital ridges (HP:0000336) | 2.17669106 |
| 40 | Acute necrotizing encephalopathy (HP:0006965) | 2.17647319 |
| 41 | Abolished electroretinogram (ERG) (HP:0000550) | 2.14686678 |
| 42 | Nephrocalcinosis (HP:0000121) | 2.14675767 |
| 43 | Increased CSF lactate (HP:0002490) | 2.13769259 |
| 44 | Drooling (HP:0002307) | 2.13005475 |
| 45 | Hypoproteinemia (HP:0003075) | 2.11712653 |
| 46 | Pancreatic fibrosis (HP:0100732) | 2.10190605 |
| 47 | Type II lissencephaly (HP:0007260) | 2.07489487 |
| 48 | Decreased central vision (HP:0007663) | 2.03436201 |
| 49 | Congenital, generalized hypertrichosis (HP:0004540) | 2.01206657 |
| 50 | Progressive macrocephaly (HP:0004481) | 2.00308340 |
| 51 | Excessive salivation (HP:0003781) | 1.99104020 |
| 52 | Renal Fanconi syndrome (HP:0001994) | 1.97256369 |
| 53 | Hepatocellular necrosis (HP:0001404) | 1.95782564 |
| 54 | Pancreatic cysts (HP:0001737) | 1.94888717 |
| 55 | Polydipsia (HP:0001959) | 1.94692506 |
| 56 | Abnormal drinking behavior (HP:0030082) | 1.94692506 |
| 57 | Absent/shortened dynein arms (HP:0200106) | 1.93420676 |
| 58 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.93420676 |
| 59 | Stomatitis (HP:0010280) | 1.91876639 |
| 60 | Acute encephalopathy (HP:0006846) | 1.88653448 |
| 61 | Attenuation of retinal blood vessels (HP:0007843) | 1.88502634 |
| 62 | Gaze-evoked nystagmus (HP:0000640) | 1.87028653 |
| 63 | Poor speech (HP:0002465) | 1.85252189 |
| 64 | Hepatic necrosis (HP:0002605) | 1.83623526 |
| 65 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.82933648 |
| 66 | Severe muscular hypotonia (HP:0006829) | 1.81953101 |
| 67 | Increased hepatocellular lipid droplets (HP:0006565) | 1.80951075 |
| 68 | Anhidrosis (HP:0000970) | 1.78250086 |
| 69 | Renal tubular dysfunction (HP:0000124) | 1.78134104 |
| 70 | Renal cortical cysts (HP:0000803) | 1.77033279 |
| 71 | Generalized aminoaciduria (HP:0002909) | 1.76857883 |
| 72 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.75088416 |
| 73 | Small hand (HP:0200055) | 1.73897930 |
| 74 | IgG deficiency (HP:0004315) | 1.72342768 |
| 75 | Pendular nystagmus (HP:0012043) | 1.70602413 |
| 76 | B lymphocytopenia (HP:0010976) | 1.69710959 |
| 77 | Petechiae (HP:0000967) | 1.68851725 |
| 78 | Lip pit (HP:0100267) | 1.68069078 |
| 79 | Abnormality of the prostate (HP:0008775) | 1.65980050 |
| 80 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.64068124 |
| 81 | Abnormality of the renal cortex (HP:0011035) | 1.63780107 |
| 82 | Abnormality of B cell number (HP:0010975) | 1.62261773 |
| 83 | Nephropathy (HP:0000112) | 1.61264115 |
| 84 | Medial flaring of the eyebrow (HP:0010747) | 1.60956152 |
| 85 | Constricted visual fields (HP:0001133) | 1.60555570 |
| 86 | Bronchitis (HP:0012387) | 1.59959407 |
| 87 | Depressed nasal tip (HP:0000437) | 1.59310858 |
| 88 | Pancytopenia (HP:0001876) | 1.55278514 |
| 89 | Thyroiditis (HP:0100646) | 1.55023460 |
| 90 | Hypomagnesemia (HP:0002917) | 1.54872793 |
| 91 | Cerebral edema (HP:0002181) | 1.51988972 |
| 92 | Agammaglobulinemia (HP:0004432) | 1.51276132 |
| 93 | Lipid accumulation in hepatocytes (HP:0006561) | 1.51189456 |
| 94 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.50437858 |
| 95 | Amniotic constriction ring (HP:0009775) | 1.49799358 |
| 96 | Abnormality of placental membranes (HP:0011409) | 1.49799358 |
| 97 | Thick eyebrow (HP:0000574) | 1.49751111 |
| 98 | Lipoatrophy (HP:0100578) | 1.49549066 |
| 99 | Abnormal ciliary motility (HP:0012262) | 1.49363334 |
| 100 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.49042534 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NTRK2 | 9.34799737 |
| 2 | MAP4K1 | 4.33739277 |
| 3 | STK3 | 3.27844423 |
| 4 | BLK | 2.45298282 |
| 5 | TXK | 2.42026466 |
| 6 | TNIK | 2.25163749 |
| 7 | FRK | 2.11273825 |
| 8 | RIPK4 | 2.08761959 |
| 9 | ZAK | 1.89874530 |
| 10 | MAP4K2 | 1.78405040 |
| 11 | BMPR2 | 1.72750232 |
| 12 | PLK4 | 1.66672832 |
| 13 | KDR | 1.64285964 |
| 14 | NUAK1 | 1.59846291 |
| 15 | ADRBK2 | 1.55632435 |
| 16 | GRK1 | 1.48266424 |
| 17 | PINK1 | 1.37947950 |
| 18 | VRK1 | 1.28379311 |
| 19 | INSRR | 1.27601188 |
| 20 | EIF2AK3 | 1.25724810 |
| 21 | VRK2 | 1.22742588 |
| 22 | TIE1 | 1.14524494 |
| 23 | WNK3 | 1.11496497 |
| 24 | MAP3K12 | 1.08476894 |
| 25 | TLK1 | 1.03286741 |
| 26 | PLK2 | 1.01182364 |
| 27 | MATK | 0.99945315 |
| 28 | STK39 | 0.99737271 |
| 29 | OXSR1 | 0.99265328 |
| 30 | TESK2 | 0.95438451 |
| 31 | MST4 | 0.93549619 |
| 32 | STK16 | 0.93164407 |
| 33 | BUB1 | 0.89888366 |
| 34 | TAOK3 | 0.89218504 |
| 35 | PRKCQ | 0.88223482 |
| 36 | BMPR1B | 0.88059809 |
| 37 | WNK4 | 0.86386625 |
| 38 | SYK | 0.86238109 |
| 39 | TEC | 0.81707707 |
| 40 | CDK8 | 0.79260761 |
| 41 | PLK3 | 0.76450684 |
| 42 | BCR | 0.76067667 |
| 43 | ERBB3 | 0.73801897 |
| 44 | MYLK | 0.73262768 |
| 45 | DAPK1 | 0.71969327 |
| 46 | MUSK | 0.69767623 |
| 47 | OBSCN | 0.68529251 |
| 48 | ACVR1B | 0.65825369 |
| 49 | TRIM28 | 0.64369099 |
| 50 | PLK1 | 0.63047705 |
| 51 | MAPK13 | 0.59667854 |
| 52 | ITK | 0.59235106 |
| 53 | STK24 | 0.58007061 |
| 54 | PIK3CG | 0.57776260 |
| 55 | KIT | 0.57572939 |
| 56 | FGFR1 | 0.56201354 |
| 57 | SRPK1 | 0.56193295 |
| 58 | PRKCE | 0.55800723 |
| 59 | IKBKB | 0.54482218 |
| 60 | NEK1 | 0.52964803 |
| 61 | PRKCG | 0.51573245 |
| 62 | PRKACA | 0.50738506 |
| 63 | BCKDK | 0.50514314 |
| 64 | STK38L | 0.49928100 |
| 65 | ROCK1 | 0.49645204 |
| 66 | CSNK1G3 | 0.49463599 |
| 67 | PHKG2 | 0.48052627 |
| 68 | PHKG1 | 0.48052627 |
| 69 | ADRBK1 | 0.47959658 |
| 70 | GRK5 | 0.47424667 |
| 71 | ABL1 | 0.47230623 |
| 72 | LCK | 0.47037143 |
| 73 | PAK3 | 0.46387455 |
| 74 | EIF2AK1 | 0.45137841 |
| 75 | HIPK2 | 0.44692020 |
| 76 | CAMK2A | 0.44562621 |
| 77 | CHUK | 0.44388869 |
| 78 | MAP3K4 | 0.44083591 |
| 79 | PRKACG | 0.43511758 |
| 80 | CDC42BPA | 0.42997283 |
| 81 | PRKCA | 0.42260704 |
| 82 | LYN | 0.41742867 |
| 83 | GRK6 | 0.38278283 |
| 84 | ROCK2 | 0.38061220 |
| 85 | CSNK1G2 | 0.37867167 |
| 86 | CSNK1G1 | 0.37692333 |
| 87 | SRC | 0.35761421 |
| 88 | SCYL2 | 0.35570643 |
| 89 | FLT3 | 0.35338980 |
| 90 | PRKG1 | 0.34703678 |
| 91 | DAPK2 | 0.34682537 |
| 92 | NLK | 0.33765467 |
| 93 | TAF1 | 0.31982791 |
| 94 | IGF1R | 0.31549500 |
| 95 | MINK1 | 0.31337271 |
| 96 | GRK7 | 0.30225923 |
| 97 | DAPK3 | 0.30167961 |
| 98 | IKBKE | 0.30089866 |
| 99 | CDK19 | 0.29865899 |
| 100 | PRKCB | 0.28964625 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 4.65576042 |
| 2 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.31513808 |
| 3 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.02225006 |
| 4 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.97808237 |
| 5 | Sulfur relay system_Homo sapiens_hsa04122 | 2.74297720 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.43742678 |
| 7 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 2.37120718 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.24270461 |
| 9 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.16408202 |
| 10 | Proteasome_Homo sapiens_hsa03050 | 2.03522567 |
| 11 | Salivary secretion_Homo sapiens_hsa04970 | 1.97353551 |
| 12 | Asthma_Homo sapiens_hsa05310 | 1.96180183 |
| 13 | Taste transduction_Homo sapiens_hsa04742 | 1.77236659 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.73424317 |
| 15 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.72795679 |
| 16 | Circadian entrainment_Homo sapiens_hsa04713 | 1.70081562 |
| 17 | Allograft rejection_Homo sapiens_hsa05330 | 1.68377658 |
| 18 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.67066999 |
| 19 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.67019011 |
| 20 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.59745782 |
| 21 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.56855375 |
| 22 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.54277851 |
| 23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.50187301 |
| 24 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.46485705 |
| 25 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.45935287 |
| 26 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.43988418 |
| 27 | Insulin secretion_Homo sapiens_hsa04911 | 1.42308427 |
| 28 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.41759391 |
| 29 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.40614750 |
| 30 | Morphine addiction_Homo sapiens_hsa05032 | 1.37166890 |
| 31 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.36629922 |
| 32 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.31913783 |
| 33 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.31674049 |
| 34 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.31230901 |
| 35 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.31086344 |
| 36 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.30821178 |
| 37 | RNA degradation_Homo sapiens_hsa03018 | 1.29465051 |
| 38 | Bile secretion_Homo sapiens_hsa04976 | 1.29453642 |
| 39 | GABAergic synapse_Homo sapiens_hsa04727 | 1.26403530 |
| 40 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.23127015 |
| 41 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.18256872 |
| 42 | Cocaine addiction_Homo sapiens_hsa05030 | 1.14245853 |
| 43 | Alzheimers disease_Homo sapiens_hsa05010 | 1.13636032 |
| 44 | Huntingtons disease_Homo sapiens_hsa05016 | 1.07722765 |
| 45 | Protein export_Homo sapiens_hsa03060 | 1.05467313 |
| 46 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.03553093 |
| 47 | Nicotine addiction_Homo sapiens_hsa05033 | 0.92594158 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.88354420 |
| 49 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.86166260 |
| 50 | Phototransduction_Homo sapiens_hsa04744 | 0.84757620 |
| 51 | RNA polymerase_Homo sapiens_hsa03020 | 0.83952799 |
| 52 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.82880412 |
| 53 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.81157279 |
| 54 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.79719051 |
| 55 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.79257746 |
| 56 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.78470836 |
| 57 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.77758188 |
| 58 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.73803728 |
| 59 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.68332006 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.67650168 |
| 61 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.66506288 |
| 62 | Platelet activation_Homo sapiens_hsa04611 | 0.64848229 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.63518488 |
| 64 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.63374860 |
| 65 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.62621631 |
| 66 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.60558491 |
| 67 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.58218594 |
| 68 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.57860437 |
| 69 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.56743836 |
| 70 | Basal transcription factors_Homo sapiens_hsa03022 | 0.56569639 |
| 71 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.56442365 |
| 72 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.54016678 |
| 73 | Melanogenesis_Homo sapiens_hsa04916 | 0.53903424 |
| 74 | Homologous recombination_Homo sapiens_hsa03440 | 0.52993157 |
| 75 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.52782302 |
| 76 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.51596432 |
| 77 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.50903660 |
| 78 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.50308916 |
| 79 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.48877025 |
| 80 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.48283354 |
| 81 | Retinol metabolism_Homo sapiens_hsa00830 | 0.47266848 |
| 82 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.46444637 |
| 83 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.46026636 |
| 84 | Gap junction_Homo sapiens_hsa04540 | 0.44878813 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44756041 |
| 86 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.44012154 |
| 87 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.41396606 |
| 88 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.40340529 |
| 89 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.39601228 |
| 90 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.39345138 |
| 91 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.36173969 |
| 92 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.34397490 |
| 93 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.33702897 |
| 94 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.32907815 |
| 95 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.31545377 |
| 96 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.27414881 |
| 97 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.26854960 |
| 98 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.25727958 |
| 99 | Circadian rhythm_Homo sapiens_hsa04710 | 0.24498234 |
| 100 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.24374245 |

