Rank | Gene Set | Z-score |
---|---|---|
1 | * ATP synthesis coupled proton transport (GO:0015986) | 9.87760137 |
2 | * energy coupled proton transport, down electrochemical gradient (GO:0015985) | 9.87760137 |
3 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 9.64849478 |
4 | * respiratory electron transport chain (GO:0022904) | 8.70823156 |
5 | * electron transport chain (GO:0022900) | 8.49207472 |
6 | ribosomal small subunit biogenesis (GO:0042274) | 5.63192540 |
7 | viral transcription (GO:0019083) | 5.42489540 |
8 | sequestering of actin monomers (GO:0042989) | 5.29927569 |
9 | * ATP biosynthetic process (GO:0006754) | 5.23990634 |
10 | ribosomal large subunit biogenesis (GO:0042273) | 5.22692126 |
11 | translational termination (GO:0006415) | 5.11912812 |
12 | * hydrogen ion transmembrane transport (GO:1902600) | 5.01207389 |
13 | chaperone-mediated protein transport (GO:0072321) | 4.97983200 |
14 | protein neddylation (GO:0045116) | 4.93815019 |
15 | * purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 4.92869755 |
16 | * purine nucleoside triphosphate biosynthetic process (GO:0009145) | 4.84310188 |
17 | cotranslational protein targeting to membrane (GO:0006613) | 4.75809360 |
18 | protein targeting to ER (GO:0045047) | 4.70826404 |
19 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.68071960 |
20 | protein complex biogenesis (GO:0070271) | 4.68049547 |
21 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.60651870 |
22 | NADH dehydrogenase complex assembly (GO:0010257) | 4.60651870 |
23 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.60651870 |
24 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.56449527 |
25 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.54815544 |
26 | protein localization to endoplasmic reticulum (GO:0070972) | 4.47475711 |
27 | oxidative phosphorylation (GO:0006119) | 4.46321460 |
28 | * proton transport (GO:0015992) | 4.41535375 |
29 | inner mitochondrial membrane organization (GO:0007007) | 4.35715483 |
30 | * hydrogen transport (GO:0006818) | 4.33673153 |
31 | * ribonucleoside triphosphate biosynthetic process (GO:0009201) | 4.24177641 |
32 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 4.23481164 |
33 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.19706594 |
34 | translational elongation (GO:0006414) | 4.07635846 |
35 | viral life cycle (GO:0019058) | 4.02453718 |
36 | mRNA catabolic process (GO:0006402) | 3.99769124 |
37 | cellular protein complex disassembly (GO:0043624) | 3.98071196 |
38 | GTP biosynthetic process (GO:0006183) | 3.87058766 |
39 | ribosomal small subunit assembly (GO:0000028) | 3.76406018 |
40 | cellular component biogenesis (GO:0044085) | 3.74733992 |
41 | regulation of oxidative phosphorylation (GO:0002082) | 3.71123225 |
42 | proteasome assembly (GO:0043248) | 3.64844442 |
43 | RNA catabolic process (GO:0006401) | 3.56664625 |
44 | * nucleoside triphosphate biosynthetic process (GO:0009142) | 3.53415520 |
45 | axon ensheathment in central nervous system (GO:0032291) | 3.48603437 |
46 | central nervous system myelination (GO:0022010) | 3.48603437 |
47 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.43286264 |
48 | aldehyde catabolic process (GO:0046185) | 3.41393958 |
49 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.34900929 |
50 | termination of RNA polymerase III transcription (GO:0006386) | 3.34900929 |
51 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.32874138 |
52 | fatty acid elongation (GO:0030497) | 3.28652313 |
53 | substantia nigra development (GO:0021762) | 3.26149171 |
54 | aerobic respiration (GO:0009060) | 3.24894315 |
55 | establishment of protein localization to organelle (GO:0072594) | 3.24685194 |
56 | protein targeting to membrane (GO:0006612) | 3.21980669 |
57 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.21856694 |
58 | * mitochondrial transport (GO:0006839) | 3.19024727 |
59 | translational initiation (GO:0006413) | 3.13617937 |
60 | protein complex disassembly (GO:0043241) | 3.12571384 |
61 | * generation of precursor metabolites and energy (GO:0006091) | 3.10660434 |
62 | UTP biosynthetic process (GO:0006228) | 3.10115016 |
63 | translation (GO:0006412) | 3.09295511 |
64 | protein localization to membrane (GO:0072657) | 3.05837506 |
65 | protein-cofactor linkage (GO:0018065) | 3.03661905 |
66 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.99201873 |
67 | viral protein processing (GO:0019082) | 2.96360826 |
68 | platelet dense granule organization (GO:0060155) | 2.95443168 |
69 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.95287548 |
70 | macromolecular complex disassembly (GO:0032984) | 2.94446816 |
71 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.94068944 |
72 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.88202794 |
73 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.88202794 |
74 | UTP metabolic process (GO:0046051) | 2.85781256 |
75 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.84889510 |
76 | regulation of cellular respiration (GO:0043457) | 2.83138224 |
77 | spliceosomal complex assembly (GO:0000245) | 2.82550647 |
78 | regulation of mitochondrial translation (GO:0070129) | 2.81070679 |
79 | maturation of SSU-rRNA (GO:0030490) | 2.80518463 |
80 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.77998230 |
81 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.77267749 |
82 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.77164485 |
83 | respiratory chain complex IV assembly (GO:0008535) | 2.76076738 |
84 | tricarboxylic acid cycle (GO:0006099) | 2.72987700 |
85 | intracellular protein transmembrane import (GO:0044743) | 2.72813078 |
86 | protein targeting to mitochondrion (GO:0006626) | 2.72458821 |
87 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.70743665 |
88 | establishment of protein localization to mitochondrion (GO:0072655) | 2.69943207 |
89 | creatine metabolic process (GO:0006600) | 2.69792027 |
90 | dopamine transport (GO:0015872) | 2.68849401 |
91 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.68464533 |
92 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.68464533 |
93 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.68184561 |
94 | negative regulation of ligase activity (GO:0051352) | 2.67843657 |
95 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.67843657 |
96 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.67602811 |
97 | cellular ketone body metabolic process (GO:0046950) | 2.66342262 |
98 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.65652448 |
99 | * purine nucleoside monophosphate biosynthetic process (GO:0009127) | 2.65013019 |
100 | * purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 2.65013019 |
101 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.64737392 |
102 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.64737392 |
103 | quinone biosynthetic process (GO:1901663) | 2.64247631 |
104 | ubiquinone biosynthetic process (GO:0006744) | 2.64247631 |
105 | behavioral response to nicotine (GO:0035095) | 2.63717104 |
106 | muscle filament sliding (GO:0030049) | 2.63574232 |
107 | actin-myosin filament sliding (GO:0033275) | 2.63574232 |
108 | cytochrome complex assembly (GO:0017004) | 2.63378234 |
109 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.63303409 |
110 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.63303409 |
111 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.63303409 |
112 | rRNA processing (GO:0006364) | 2.58645640 |
113 | sarcomere organization (GO:0045214) | 2.58122521 |
114 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.56251965 |
115 | negative regulation of protein localization to cell surface (GO:2000009) | 2.56096692 |
116 | protein localization to mitochondrion (GO:0070585) | 2.55889527 |
117 | * purine ribonucleoside biosynthetic process (GO:0046129) | 2.55173329 |
118 | * purine nucleoside biosynthetic process (GO:0042451) | 2.55173329 |
119 | heart contraction (GO:0060047) | 2.53762939 |
120 | heart process (GO:0003015) | 2.53762939 |
121 | ubiquinone metabolic process (GO:0006743) | 2.53671761 |
122 | calcium-mediated signaling using intracellular calcium source (GO:0035584) | 2.53213490 |
123 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 2.49942536 |
124 | cholesterol biosynthetic process (GO:0006695) | 2.47505620 |
125 | regulation of cell communication by electrical coupling (GO:0010649) | 2.45426677 |
126 | CTP biosynthetic process (GO:0006241) | 2.44881809 |
127 | CTP metabolic process (GO:0046036) | 2.44881809 |
128 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 2.43631040 |
129 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.42541428 |
130 | establishment of protein localization to membrane (GO:0090150) | 2.42214001 |
131 | cellular respiration (GO:0045333) | 2.41950621 |
132 | mitochondrion morphogenesis (GO:0070584) | 2.41557992 |
133 | regulation of dopamine metabolic process (GO:0042053) | 2.38138772 |
134 | regulation of catecholamine metabolic process (GO:0042069) | 2.38138772 |
135 | long-chain fatty acid biosynthetic process (GO:0042759) | 2.38004875 |
136 | ketone body metabolic process (GO:1902224) | 2.36878073 |
137 | protein targeting (GO:0006605) | 2.36567210 |
138 | * mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 10.2486617 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 6.30454478 |
2 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.80742178 |
3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.69028575 |
4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.14875175 |
5 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.86278624 |
6 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.85039691 |
7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.82954128 |
8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.79231972 |
9 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.77983741 |
10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.73503004 |
11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.40916689 |
12 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.40916271 |
13 | * ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 2.40528503 |
14 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.35500502 |
15 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.30162889 |
16 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.19293292 |
17 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.17877349 |
18 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.02289707 |
19 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 2.01127352 |
20 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.96299317 |
21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.95196167 |
22 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.91969990 |
23 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.91424510 |
24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.88502344 |
25 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.87496061 |
26 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.87298878 |
27 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.87295949 |
28 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.83908572 |
29 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.82628119 |
30 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.77452709 |
31 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.76909004 |
32 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.75986884 |
33 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.74402381 |
34 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.74168167 |
35 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.72804840 |
36 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.69124160 |
37 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.62558009 |
38 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.61313368 |
39 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.60788182 |
40 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.58181955 |
41 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.57776260 |
42 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.56483772 |
43 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55446788 |
44 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.53530784 |
45 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.53249749 |
46 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.53079669 |
47 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.50683132 |
48 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.50563020 |
49 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.44464260 |
50 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.43050021 |
51 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.43015459 |
52 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.39596489 |
53 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.38260221 |
54 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.38163064 |
55 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.38086233 |
56 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.35683259 |
57 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.35647683 |
58 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.34032380 |
59 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.31705172 |
60 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.30922771 |
61 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25479604 |
62 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24670217 |
63 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.23898182 |
64 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.23665278 |
65 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.23189716 |
66 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.20457689 |
67 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.20457689 |
68 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.19084618 |
69 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.15891138 |
70 | * POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.15082313 |
71 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.12478916 |
72 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.12177081 |
73 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.11911640 |
74 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.10470990 |
75 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10253592 |
76 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.10116985 |
77 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.09799763 |
78 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.09624051 |
79 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.08027969 |
80 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.07962318 |
81 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.07603316 |
82 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.07111056 |
83 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.07035236 |
84 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.06101319 |
85 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.05169919 |
86 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.04672607 |
87 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.04644486 |
88 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.01522167 |
89 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.00180417 |
90 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.99312579 |
91 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.99297788 |
92 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.99297788 |
93 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.98625981 |
94 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.98244141 |
95 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.97620764 |
96 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.95871755 |
97 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.95597003 |
98 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.95098766 |
99 | P300_19829295_ChIP-Seq_ESCs_Human | 0.94795162 |
100 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.94733388 |
101 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.93046964 |
102 | AR_20517297_ChIP-Seq_VCAP_Human | 0.92721625 |
103 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.92274320 |
104 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.91322617 |
105 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.91079524 |
106 | * KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.89693689 |
107 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.89541274 |
108 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.89456599 |
109 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.89333270 |
110 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.89176233 |
111 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.88834467 |
112 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.87050373 |
113 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.86900754 |
114 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.86858264 |
115 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.86286223 |
116 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.85574448 |
117 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.85532386 |
118 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85446384 |
119 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.85152046 |
120 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.85027350 |
121 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.84664970 |
122 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.84198469 |
123 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.84121765 |
124 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.84029875 |
125 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.83843635 |
126 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.83028875 |
127 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.82663950 |
128 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.82588303 |
129 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.82575689 |
130 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.82106849 |
131 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.80657188 |
132 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.80007370 |
133 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.79879146 |
134 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.79286960 |
135 | * FUS_26573619_Chip-Seq_HEK293_Human | 0.78978960 |
136 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.78786320 |
137 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.78647345 |
138 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.77864143 |
139 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.77598746 |
140 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.76609694 |
141 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.76247809 |
142 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.75418142 |
143 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.74566274 |
144 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.74338435 |
145 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.74033977 |
146 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 0.74022658 |
147 | NCOR_22424771_ChIP-Seq_293T_Human | 0.74010136 |
148 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.73493765 |
149 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.73115186 |
150 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.72961429 |
151 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.72817857 |
152 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.71364830 |
153 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.71011360 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002837_dystrophic_cardiac_calcinosis | 4.93008553 |
2 | MP0009379_abnormal_foot_pigmentation | 4.22707457 |
3 | MP0001529_abnormal_vocalization | 3.28200156 |
4 | MP0003880_abnormal_central_pattern | 3.03101866 |
5 | MP0003646_muscle_fatigue | 2.90014254 |
6 | MP0000751_myopathy | 2.69749900 |
7 | MP0006036_abnormal_mitochondrial_physio | 2.62525655 |
8 | MP0001905_abnormal_dopamine_level | 2.41227586 |
9 | MP0000749_muscle_degeneration | 2.39667034 |
10 | MP0003136_yellow_coat_color | 2.27319834 |
11 | MP0005084_abnormal_gallbladder_morpholo | 2.25781560 |
12 | MP0004036_abnormal_muscle_relaxation | 2.23804473 |
13 | MP0006276_abnormal_autonomic_nervous | 2.23688824 |
14 | MP0004215_abnormal_myocardial_fiber | 2.14612505 |
15 | MP0004145_abnormal_muscle_electrophysio | 1.97085641 |
16 | MP0005330_cardiomyopathy | 1.91638547 |
17 | MP0003195_calcinosis | 1.83790057 |
18 | MP0003123_paternal_imprinting | 1.79742938 |
19 | MP0004084_abnormal_cardiac_muscle | 1.75337448 |
20 | MP0006035_abnormal_mitochondrial_morpho | 1.75332558 |
21 | MP0004043_abnormal_pH_regulation | 1.65978280 |
22 | MP0004142_abnormal_muscle_tone | 1.65394504 |
23 | MP0003137_abnormal_impulse_conducting | 1.64128727 |
24 | MP0005451_abnormal_body_composition | 1.62985764 |
25 | MP0001440_abnormal_grooming_behavior | 1.61685496 |
26 | MP0005671_abnormal_response_to | 1.61195942 |
27 | MP0006292_abnormal_olfactory_placode | 1.60133280 |
28 | MP0003806_abnormal_nucleotide_metabolis | 1.58846482 |
29 | MP0002638_abnormal_pupillary_reflex | 1.58079311 |
30 | MP0002736_abnormal_nociception_after | 1.53806167 |
31 | MP0000920_abnormal_myelination | 1.50892141 |
32 | MP0003787_abnormal_imprinting | 1.49514231 |
33 | MP0003122_maternal_imprinting | 1.47461865 |
34 | MP0002909_abnormal_adrenal_gland | 1.46666691 |
35 | MP0002972_abnormal_cardiac_muscle | 1.42346856 |
36 | MP0008875_abnormal_xenobiotic_pharmacok | 1.41775624 |
37 | MP0000750_abnormal_muscle_regeneration | 1.41764245 |
38 | MP0004381_abnormal_hair_follicle | 1.41384645 |
39 | MP0004019_abnormal_vitamin_homeostasis | 1.40774250 |
40 | MP0002106_abnormal_muscle_physiology | 1.40065624 |
41 | MP0001968_abnormal_touch/_nociception | 1.39989565 |
42 | MP0005645_abnormal_hypothalamus_physiol | 1.37924760 |
43 | MP0005083_abnormal_biliary_tract | 1.37329157 |
44 | MP0004742_abnormal_vestibular_system | 1.35979144 |
45 | MP0002653_abnormal_ependyma_morphology | 1.35897759 |
46 | MP0005620_abnormal_muscle_contractility | 1.35187707 |
47 | MP0003186_abnormal_redox_activity | 1.35180814 |
48 | MP0002272_abnormal_nervous_system | 1.34419408 |
49 | MP0002332_abnormal_exercise_endurance | 1.31388363 |
50 | MP0005379_endocrine/exocrine_gland_phen | 1.31136423 |
51 | MP0000343_altered_response_to | 1.31051290 |
52 | MP0008995_early_reproductive_senescence | 1.25609972 |
53 | MP0005360_urolithiasis | 1.23923106 |
54 | MP0002148_abnormal_hypersensitivity_rea | 1.22851922 |
55 | MP0002822_catalepsy | 1.21979710 |
56 | MP0005535_abnormal_body_temperature | 1.21219108 |
57 | MP0001919_abnormal_reproductive_system | 1.20389020 |
58 | MP0001727_abnormal_embryo_implantation | 1.20183758 |
59 | MP0005646_abnormal_pituitary_gland | 1.19806525 |
60 | MP0003011_delayed_dark_adaptation | 1.18562146 |
61 | MP0005085_abnormal_gallbladder_physiolo | 1.17749594 |
62 | MP0005332_abnormal_amino_acid | 1.17637537 |
63 | MP0001485_abnormal_pinna_reflex | 1.17237603 |
64 | MP0002163_abnormal_gland_morphology | 1.15786437 |
65 | MP0009745_abnormal_behavioral_response | 1.14427311 |
66 | MP0005369_muscle_phenotype | 1.14381542 |
67 | MP0006072_abnormal_retinal_apoptosis | 1.14325707 |
68 | MP0002095_abnormal_skin_pigmentation | 1.12531197 |
69 | MP0002064_seizures | 1.12306836 |
70 | MP0004484_altered_response_of | 1.11816462 |
71 | MP0005409_darkened_coat_color | 1.11782242 |
72 | MP0003121_genomic_imprinting | 1.11470450 |
73 | MP0008872_abnormal_physiological_respon | 1.11037018 |
74 | MP0004147_increased_porphyrin_level | 1.10676677 |
75 | MP0001970_abnormal_pain_threshold | 1.09175869 |
76 | MP0003638_abnormal_response/metabolism_ | 1.08185158 |
77 | MP0001756_abnormal_urination | 1.07631462 |
78 | MP0005636_abnormal_mineral_homeostasis | 1.07549334 |
79 | MP0002938_white_spotting | 1.07332247 |
80 | MP0004085_abnormal_heartbeat | 1.05795722 |
81 | MP0002132_abnormal_respiratory_system | 1.05477149 |
82 | MP0000747_muscle_weakness | 1.05372315 |
83 | MP0003950_abnormal_plasma_membrane | 1.04453466 |
84 | MP0002693_abnormal_pancreas_physiology | 1.04420145 |
85 | MP0000631_abnormal_neuroendocrine_gland | 1.03702545 |
86 | MP0003879_abnormal_hair_cell | 1.03099218 |
87 | MP0005075_abnormal_melanosome_morpholog | 1.02933056 |
88 | MP0009785_altered_susceptibility_to | 1.02776886 |
89 | MP0002734_abnormal_mechanical_nocicepti | 1.02312601 |
90 | MP0010386_abnormal_urinary_bladder | 1.01903837 |
91 | MP0005389_reproductive_system_phenotype | 1.01826370 |
92 | MP0002735_abnormal_chemical_nociception | 1.01698929 |
93 | MP0000372_irregular_coat_pigmentation | 1.00798111 |
94 | MP0005385_cardiovascular_system_phenoty | 1.00694740 |
95 | MP0001544_abnormal_cardiovascular_syste | 1.00694740 |
96 | MP0000013_abnormal_adipose_tissue | 1.00637013 |
97 | MP0004087_abnormal_muscle_fiber | 1.00497833 |
98 | MP0008775_abnormal_heart_ventricle | 1.00361761 |
99 | MP0004924_abnormal_behavior | 1.00035891 |
100 | MP0005386_behavior/neurological_phenoty | 1.00035891 |
101 | MP0002139_abnormal_hepatobiliary_system | 0.99200235 |
102 | MP0002572_abnormal_emotion/affect_behav | 0.98671839 |
103 | MP0002733_abnormal_thermal_nociception | 0.98230778 |
104 | MP0004270_analgesia | 0.97119932 |
105 | MP0005253_abnormal_eye_physiology | 0.97027840 |
106 | MP0006082_CNS_inflammation | 0.96586966 |
107 | MP0009764_decreased_sensitivity_to | 0.96240235 |
108 | MP0001764_abnormal_homeostasis | 0.94492118 |
109 | MP0005165_increased_susceptibility_to | 0.94019871 |
110 | MP0000759_abnormal_skeletal_muscle | 0.93204486 |
111 | MP0001486_abnormal_startle_reflex | 0.92818113 |
112 | MP0004133_heterotaxia | 0.89841858 |
113 | MP0001835_abnormal_antigen_presentation | 0.89667397 |
114 | MP0002160_abnormal_reproductive_system | 0.88914776 |
115 | MP0002557_abnormal_social/conspecific_i | 0.87603139 |
116 | MP0001984_abnormal_olfaction | 0.87334978 |
117 | MP0002067_abnormal_sensory_capabilities | 0.87092903 |
118 | MP0001944_abnormal_pancreas_morphology | 0.87041098 |
119 | MP0000230_abnormal_systemic_arterial | 0.86627316 |
120 | MP0003329_amyloid_beta_deposits | 0.85858454 |
121 | MP0005551_abnormal_eye_electrophysiolog | 0.84134518 |
122 | MP0002876_abnormal_thyroid_physiology | 0.84067385 |
123 | MP0004130_abnormal_muscle_cell | 0.84016137 |
124 | MP0005171_absent_coat_pigmentation | 0.83665585 |
125 | MP0005408_hypopigmentation | 0.83521193 |
126 | MP0005058_abnormal_lysosome_morphology | 0.83466281 |
127 | MP0002102_abnormal_ear_morphology | 0.81970228 |
128 | MP0005195_abnormal_posterior_eye | 0.81736730 |
129 | MP0001501_abnormal_sleep_pattern | 0.79874694 |
130 | MP0002295_abnormal_pulmonary_circulatio | 0.79654742 |
131 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.77959416 |
132 | MP0006138_congestive_heart_failure | 0.77924463 |
133 | MP0000538_abnormal_urinary_bladder | 0.77691634 |
134 | MP0009046_muscle_twitch | 0.77478457 |
135 | MP0005423_abnormal_somatic_nervous | 0.77312841 |
136 | MP0002928_abnormal_bile_duct | 0.77284899 |
137 | MP0002090_abnormal_vision | 0.76643027 |
138 | MP0000026_abnormal_inner_ear | 0.76321057 |
139 | MP0005266_abnormal_metabolism | 0.75969117 |
140 | MP0008789_abnormal_olfactory_epithelium | 0.75321300 |
141 | MP0000778_abnormal_nervous_system | 0.75297529 |
142 | MP0003878_abnormal_ear_physiology | 0.74338237 |
143 | MP0005377_hearing/vestibular/ear_phenot | 0.74338237 |
144 | MP0005174_abnormal_tail_pigmentation | 0.74133121 |
145 | MP0003315_abnormal_perineum_morphology | 0.72991109 |
146 | MP0002277_abnormal_respiratory_mucosa | 0.72932201 |
147 | MP0001663_abnormal_digestive_system | 0.70923461 |
148 | MP0003690_abnormal_glial_cell | 0.70798134 |
149 | MP0003724_increased_susceptibility_to | 0.70414088 |
150 | MP0001853_heart_inflammation | 0.69359420 |
151 | MP0009643_abnormal_urine_homeostasis | 0.69177726 |
152 | MP0005448_abnormal_energy_balance | 0.68321357 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 7.66474313 |
2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 6.95270060 |
3 | Acute encephalopathy (HP:0006846) | 6.56423875 |
4 | Mitochondrial inheritance (HP:0001427) | 6.51548510 |
5 | Progressive macrocephaly (HP:0004481) | 6.49415266 |
6 | Increased CSF lactate (HP:0002490) | 5.44755561 |
7 | Hepatocellular necrosis (HP:0001404) | 5.41781518 |
8 | Increased hepatocellular lipid droplets (HP:0006565) | 5.28623315 |
9 | Hepatic necrosis (HP:0002605) | 5.09591999 |
10 | Lipid accumulation in hepatocytes (HP:0006561) | 4.98939280 |
11 | Cerebral edema (HP:0002181) | 4.95609824 |
12 | Renal Fanconi syndrome (HP:0001994) | 4.80106731 |
13 | Increased intramyocellular lipid droplets (HP:0012240) | 4.45762791 |
14 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 4.30919687 |
15 | Increased muscle lipid content (HP:0009058) | 4.09274517 |
16 | Optic disc pallor (HP:0000543) | 3.99434264 |
17 | Exercise intolerance (HP:0003546) | 3.97838621 |
18 | Respiratory failure (HP:0002878) | 3.91738082 |
19 | Leukodystrophy (HP:0002415) | 3.81727473 |
20 | Abnormality of glycolysis (HP:0004366) | 3.79979162 |
21 | Increased serum pyruvate (HP:0003542) | 3.79979162 |
22 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.76439299 |
23 | * Lactic acidosis (HP:0003128) | 3.60973143 |
24 | Congenital, generalized hypertrichosis (HP:0004540) | 3.60000745 |
25 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.51862126 |
26 | Muscle hypertrophy of the lower extremities (HP:0008968) | 3.42338648 |
27 | Exertional dyspnea (HP:0002875) | 3.41705824 |
28 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.41045658 |
29 | Calf muscle hypertrophy (HP:0008981) | 3.23899157 |
30 | Abnormality of renal resorption (HP:0011038) | 3.22295855 |
31 | Increased serum lactate (HP:0002151) | 3.06254299 |
32 | Parakeratosis (HP:0001036) | 3.05019591 |
33 | Abnormal number of erythroid precursors (HP:0012131) | 2.98714807 |
34 | Abnormality of urine glucose concentration (HP:0011016) | 2.89252741 |
35 | Glycosuria (HP:0003076) | 2.89252741 |
36 | Sudden death (HP:0001699) | 2.88582909 |
37 | Respiratory difficulties (HP:0002880) | 2.85406369 |
38 | Lethargy (HP:0001254) | 2.68482542 |
39 | Hyperphosphaturia (HP:0003109) | 2.67374133 |
40 | X-linked dominant inheritance (HP:0001423) | 2.66476858 |
41 | Macrocytic anemia (HP:0001972) | 2.60270452 |
42 | Exercise-induced myalgia (HP:0003738) | 2.54524122 |
43 | Neuroendocrine neoplasm (HP:0100634) | 2.50499716 |
44 | Pheochromocytoma (HP:0002666) | 2.50452996 |
45 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.47471692 |
46 | Molar tooth sign on MRI (HP:0002419) | 2.46235037 |
47 | Abnormality of midbrain morphology (HP:0002418) | 2.46235037 |
48 | Aplastic anemia (HP:0001915) | 2.39569982 |
49 | CNS demyelination (HP:0007305) | 2.38152346 |
50 | Abnormal urine phosphate concentration (HP:0012599) | 2.32303113 |
51 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.32099927 |
52 | Palpitations (HP:0001962) | 2.31981007 |
53 | Conjunctival hamartoma (HP:0100780) | 2.30664759 |
54 | * 3-Methylglutaconic aciduria (HP:0003535) | 2.25700211 |
55 | Dicarboxylic aciduria (HP:0003215) | 2.24570100 |
56 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.24570100 |
57 | Concave nail (HP:0001598) | 2.23790590 |
58 | Muscle fiber splitting (HP:0003555) | 2.19452353 |
59 | Myoglobinuria (HP:0002913) | 2.17962144 |
60 | Vomiting (HP:0002013) | 2.17941511 |
61 | Cerebral hemorrhage (HP:0001342) | 2.15538926 |
62 | Reticulocytopenia (HP:0001896) | 2.11310623 |
63 | * Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.10219715 |
64 | * Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.10219715 |
65 | Limb dystonia (HP:0002451) | 2.08494354 |
66 | Muscle stiffness (HP:0003552) | 2.06932875 |
67 | Type I transferrin isoform profile (HP:0003642) | 2.05574262 |
68 | Myotonia (HP:0002486) | 2.04457456 |
69 | Abnormality of the calf musculature (HP:0001430) | 2.03638362 |
70 | Emotional lability (HP:0000712) | 2.01001624 |
71 | Generalized aminoaciduria (HP:0002909) | 2.00279759 |
72 | Ventricular tachycardia (HP:0004756) | 2.00121001 |
73 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.97803393 |
74 | Rhabdomyolysis (HP:0003201) | 1.97622686 |
75 | Ketoacidosis (HP:0001993) | 1.97609048 |
76 | Exercise-induced muscle cramps (HP:0003710) | 1.93388532 |
77 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.93247389 |
78 | Abnormal pupillary function (HP:0007686) | 1.90562202 |
79 | Sensory axonal neuropathy (HP:0003390) | 1.88968916 |
80 | Medial flaring of the eyebrow (HP:0010747) | 1.88361211 |
81 | Esophageal neoplasm (HP:0100751) | 1.87979315 |
82 | Neoplasm of head and neck (HP:0012288) | 1.87979315 |
83 | Methylmalonic aciduria (HP:0012120) | 1.87791835 |
84 | Pallor (HP:0000980) | 1.86964588 |
85 | Pancreatic cysts (HP:0001737) | 1.86373121 |
86 | Agitation (HP:0000713) | 1.85978505 |
87 | Renal tubular dysfunction (HP:0000124) | 1.84424897 |
88 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.82789871 |
89 | Oral leukoplakia (HP:0002745) | 1.81207261 |
90 | Methylmalonic acidemia (HP:0002912) | 1.80996875 |
91 | Hyperalaninemia (HP:0003348) | 1.80599542 |
92 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.80599542 |
93 | Abnormality of alanine metabolism (HP:0010916) | 1.80599542 |
94 | Pancreatic fibrosis (HP:0100732) | 1.80341525 |
95 | Amniotic constriction ring (HP:0009775) | 1.80179857 |
96 | Abnormality of placental membranes (HP:0011409) | 1.80179857 |
97 | Nausea (HP:0002018) | 1.78917188 |
98 | Myokymia (HP:0002411) | 1.78082195 |
99 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.77678372 |
100 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.77678372 |
101 | Ketosis (HP:0001946) | 1.75603383 |
102 | Abnormal hemoglobin (HP:0011902) | 1.75086363 |
103 | Blindness (HP:0000618) | 1.74228081 |
104 | Abnormal ciliary motility (HP:0012262) | 1.73017658 |
105 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.70838545 |
106 | Vacuolated lymphocytes (HP:0001922) | 1.69794756 |
107 | Hyperthyroidism (HP:0000836) | 1.69498610 |
108 | Prolonged QT interval (HP:0001657) | 1.69208090 |
109 | Muscle fiber inclusion bodies (HP:0100299) | 1.68776963 |
110 | Abnormality of glycolipid metabolism (HP:0010969) | 1.67841513 |
111 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.67841513 |
112 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.67841513 |
113 | Polyphagia (HP:0002591) | 1.65596314 |
114 | Lipoatrophy (HP:0100578) | 1.65327781 |
115 | True hermaphroditism (HP:0010459) | 1.64252058 |
116 | EMG: myopathic abnormalities (HP:0003458) | 1.63974336 |
117 | Hypothermia (HP:0002045) | 1.63580548 |
118 | Double outlet right ventricle (HP:0001719) | 1.63513824 |
119 | Congenital malformation of the right heart (HP:0011723) | 1.63513824 |
120 | Nephronophthisis (HP:0000090) | 1.62940300 |
121 | Syncope (HP:0001279) | 1.62507599 |
122 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.61751966 |
123 | Abnormality of secondary sexual hair (HP:0009888) | 1.59992134 |
124 | Abnormality of the axillary hair (HP:0100134) | 1.59992134 |
125 | Hypoglycemic coma (HP:0001325) | 1.58662824 |
126 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.58045945 |
127 | Poor suck (HP:0002033) | 1.57686368 |
128 | Depressed nasal ridge (HP:0000457) | 1.57596794 |
129 | Hyporeflexia of lower limbs (HP:0002600) | 1.57467265 |
130 | Metabolic acidosis (HP:0001942) | 1.57439285 |
131 | Nemaline bodies (HP:0003798) | 1.57246193 |
132 | Gliosis (HP:0002171) | 1.56759170 |
133 | Sclerocornea (HP:0000647) | 1.54459283 |
134 | Neurofibrillary tangles (HP:0002185) | 1.54266522 |
135 | Absent thumb (HP:0009777) | 1.53951906 |
136 | Degeneration of anterior horn cells (HP:0002398) | 1.53767207 |
137 | Abnormality of the anterior horn cell (HP:0006802) | 1.53767207 |
138 | Testicular atrophy (HP:0000029) | 1.53350557 |
139 | Petechiae (HP:0000967) | 1.52843154 |
140 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.49448030 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NME2 | 3.82106394 |
2 | VRK2 | 3.64112021 |
3 | NME1 | 3.50497028 |
4 | STK39 | 3.15852581 |
5 | MYLK | 2.75578845 |
6 | OBSCN | 2.69214162 |
7 | WNK4 | 2.60930083 |
8 | GRK7 | 2.40987522 |
9 | PBK | 2.28576065 |
10 | MST4 | 2.25722353 |
11 | OXSR1 | 2.09850291 |
12 | ARAF | 2.09681173 |
13 | MUSK | 2.08235452 |
14 | STK16 | 2.07024324 |
15 | BCKDK | 1.98949364 |
16 | PHKG1 | 1.90894757 |
17 | PHKG2 | 1.90894757 |
18 | CASK | 1.84815403 |
19 | MAP3K12 | 1.77432689 |
20 | LIMK1 | 1.76082088 |
21 | TNIK | 1.74683276 |
22 | TESK1 | 1.73277775 |
23 | PNCK | 1.68758479 |
24 | MAPK15 | 1.61789514 |
25 | ZAK | 1.61614516 |
26 | PKN1 | 1.61153493 |
27 | GRK5 | 1.60817352 |
28 | MAP3K11 | 1.49553811 |
29 | UHMK1 | 1.44758767 |
30 | EIF2AK1 | 1.41899833 |
31 | DYRK3 | 1.39752986 |
32 | BCR | 1.29597102 |
33 | ADRBK2 | 1.27035018 |
34 | CAMK2D | 1.23350940 |
35 | PIK3CG | 1.21127303 |
36 | BUB1 | 1.20397494 |
37 | IRAK2 | 1.18986436 |
38 | TTN | 1.18059930 |
39 | TLK1 | 1.17032309 |
40 | ABL2 | 1.16929646 |
41 | BMPR1B | 1.16209713 |
42 | CAMK2B | 1.13021361 |
43 | FGR | 1.10974508 |
44 | DYRK2 | 1.09894884 |
45 | VRK1 | 1.08568945 |
46 | MAPKAPK5 | 1.07549741 |
47 | PIM2 | 1.06659692 |
48 | ILK | 1.06462061 |
49 | CDK19 | 1.04157756 |
50 | WNK3 | 1.03345162 |
51 | CAMK2A | 1.02985408 |
52 | MST1R | 1.02382616 |
53 | RIPK4 | 1.02009736 |
54 | MAP4K2 | 1.00889937 |
55 | ADRBK1 | 1.00425088 |
56 | ROCK2 | 0.98912412 |
57 | MARK1 | 0.95422957 |
58 | INSRR | 0.94391012 |
59 | CAMK2G | 0.93577288 |
60 | DAPK3 | 0.93066128 |
61 | BMPR2 | 0.92464365 |
62 | PIK3CA | 0.91157256 |
63 | MAPK13 | 0.87024326 |
64 | MAP2K2 | 0.84937553 |
65 | TXK | 0.84921046 |
66 | TAOK3 | 0.84300027 |
67 | IKBKB | 0.83888807 |
68 | PINK1 | 0.83269697 |
69 | TIE1 | 0.83244045 |
70 | CAMKK2 | 0.81376156 |
71 | EPHB1 | 0.80957651 |
72 | AURKA | 0.79425945 |
73 | CSNK1G3 | 0.77155301 |
74 | PRKCE | 0.76310633 |
75 | PDK4 | 0.76280800 |
76 | PDK3 | 0.76280800 |
77 | CDC7 | 0.75647005 |
78 | PRKACA | 0.74973615 |
79 | PASK | 0.74750786 |
80 | LMTK2 | 0.73448541 |
81 | BRAF | 0.73093432 |
82 | PAK3 | 0.71697412 |
83 | MAP3K4 | 0.71481234 |
84 | MINK1 | 0.69795040 |
85 | MAPK12 | 0.67534227 |
86 | FES | 0.66246964 |
87 | CSNK2A1 | 0.66171705 |
88 | MAP2K6 | 0.65873948 |
89 | WEE1 | 0.64633558 |
90 | PRKCQ | 0.63001470 |
91 | MAP2K4 | 0.62253221 |
92 | AURKB | 0.61276218 |
93 | EPHB2 | 0.60872864 |
94 | CDK8 | 0.58070271 |
95 | RPS6KB2 | 0.58051785 |
96 | LRRK2 | 0.57856031 |
97 | IRAK1 | 0.57596279 |
98 | KDR | 0.56298423 |
99 | LYN | 0.55737830 |
100 | EPHA4 | 0.55276667 |
101 | MAPK4 | 0.54903706 |
102 | GRK6 | 0.54898191 |
103 | PDK2 | 0.54867398 |
104 | SRPK1 | 0.54234081 |
105 | BLK | 0.51335476 |
106 | PTK2B | 0.50601845 |
107 | MAP2K7 | 0.48769933 |
108 | PRKD1 | 0.48169181 |
109 | RPS6KA5 | 0.47538723 |
110 | SCYL2 | 0.45392872 |
111 | ROCK1 | 0.45305692 |
112 | GRK1 | 0.44791212 |
113 | PRKCI | 0.44217525 |
114 | MARK3 | 0.43841530 |
115 | MATK | 0.42504319 |
116 | DYRK1B | 0.42360717 |
117 | CSNK1G2 | 0.41634365 |
118 | PAK1 | 0.41490177 |
119 | STK24 | 0.40008235 |
120 | MET | 0.39456130 |
121 | CSNK1G1 | 0.39300696 |
122 | PAK4 | 0.38984154 |
123 | CCNB1 | 0.37175594 |
124 | PRKG1 | 0.36955848 |
125 | DAPK1 | 0.36677881 |
126 | IRAK4 | 0.35755287 |
127 | TESK2 | 0.35083017 |
128 | SYK | 0.34629114 |
129 | TAF1 | 0.34347986 |
130 | CDK14 | 0.34287475 |
131 | EIF2AK3 | 0.34251071 |
132 | PRKCG | 0.33290149 |
133 | NTRK3 | 0.33082960 |
134 | PRKCD | 0.32282185 |
135 | PRKCA | 0.31540544 |
136 | PRKACG | 0.30469337 |
137 | CSNK2A2 | 0.30370458 |
138 | NTRK2 | 0.29544249 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Oxidative phosphorylation_Homo sapiens_hsa00190 | 6.67387758 |
2 | Parkinsons disease_Homo sapiens_hsa05012 | 5.67307515 |
3 | Alzheimers disease_Homo sapiens_hsa05010 | 4.46583907 |
4 | Ribosome_Homo sapiens_hsa03010 | 4.03005585 |
5 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 3.95311933 |
6 | Huntingtons disease_Homo sapiens_hsa05016 | 3.88640704 |
7 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.29630226 |
8 | Proteasome_Homo sapiens_hsa03050 | 2.38628609 |
9 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.36256412 |
10 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.33633631 |
11 | Protein export_Homo sapiens_hsa03060 | 2.26364289 |
12 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.88209626 |
13 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.87738467 |
14 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.74732153 |
15 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.71719840 |
16 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.55202357 |
17 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.45471213 |
18 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.38830313 |
19 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.29776627 |
20 | RNA polymerase_Homo sapiens_hsa03020 | 1.27901158 |
21 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.27856515 |
22 | Homologous recombination_Homo sapiens_hsa03440 | 1.16765521 |
23 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.16550746 |
24 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.12643464 |
25 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.08042873 |
26 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.05288499 |
27 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.04154121 |
28 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.03493270 |
29 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.00704455 |
30 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.96975706 |
31 | Peroxisome_Homo sapiens_hsa04146 | 0.94285122 |
32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.94284259 |
33 | Mismatch repair_Homo sapiens_hsa03430 | 0.94222665 |
34 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.94168336 |
35 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.92505430 |
36 | Spliceosome_Homo sapiens_hsa03040 | 0.91396536 |
37 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.88205138 |
38 | Carbon metabolism_Homo sapiens_hsa01200 | 0.85960688 |
39 | Histidine metabolism_Homo sapiens_hsa00340 | 0.84030183 |
40 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.81217293 |
41 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.81208811 |
42 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.80791386 |
43 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.79797089 |
44 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.79258916 |
45 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.74909649 |
46 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.74828987 |
47 | Basal transcription factors_Homo sapiens_hsa03022 | 0.74442936 |
48 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.71610527 |
49 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.67969076 |
50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.67278781 |
51 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.66528368 |
52 | Sulfur relay system_Homo sapiens_hsa04122 | 0.65514748 |
53 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.64351657 |
54 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.63594175 |
55 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.63030424 |
56 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.63028336 |
57 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.62501293 |
58 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.62002625 |
59 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.60837689 |
60 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.59779669 |
61 | RNA degradation_Homo sapiens_hsa03018 | 0.58776190 |
62 | DNA replication_Homo sapiens_hsa03030 | 0.58721244 |
63 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.58533455 |
64 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.57173293 |
65 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.54850309 |
66 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.54569558 |
67 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.54461464 |
68 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.52973139 |
69 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.52500658 |
70 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.51939480 |
71 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.51292871 |
72 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.48626252 |
73 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.46673836 |
74 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.46060209 |
75 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.45510662 |
76 | Mineral absorption_Homo sapiens_hsa04978 | 0.43048237 |
77 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.42456218 |
78 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.41716725 |
79 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.39837217 |
80 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.39811978 |
81 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.39442650 |
82 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.38976386 |
83 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.37863137 |
84 | Phototransduction_Homo sapiens_hsa04744 | 0.32871949 |
85 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.32800133 |
86 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.32450471 |
87 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.32302359 |
88 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.32145362 |
89 | Nicotine addiction_Homo sapiens_hsa05033 | 0.31307970 |
90 | Taste transduction_Homo sapiens_hsa04742 | 0.28935190 |
91 | Retinol metabolism_Homo sapiens_hsa00830 | 0.28218560 |
92 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.27667650 |
93 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.27587713 |
94 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.26252297 |
95 | Phagosome_Homo sapiens_hsa04145 | 0.26081274 |
96 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.25175727 |
97 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.24429864 |
98 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.24277921 |
99 | Asthma_Homo sapiens_hsa05310 | 0.24213198 |
100 | Lysosome_Homo sapiens_hsa04142 | 0.23730419 |
101 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.23592706 |
102 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.23490219 |
103 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.22226646 |
104 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.22183918 |
105 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.21654120 |
106 | Purine metabolism_Homo sapiens_hsa00230 | 0.21242458 |
107 | Base excision repair_Homo sapiens_hsa03410 | 0.20242280 |
108 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.20237463 |
109 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.19958549 |
110 | GABAergic synapse_Homo sapiens_hsa04727 | 0.19762367 |
111 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.19745186 |
112 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.19589976 |
113 | Alcoholism_Homo sapiens_hsa05034 | 0.19095923 |
114 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.18657653 |
115 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.18232595 |
116 | Allograft rejection_Homo sapiens_hsa05330 | 0.16598800 |
117 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.16183173 |
118 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.15411802 |
119 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.15346780 |
120 | Olfactory transduction_Homo sapiens_hsa04740 | 0.12596229 |
121 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.12148036 |
122 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.11854770 |
123 | Renin secretion_Homo sapiens_hsa04924 | 0.11709245 |
124 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.11695128 |
125 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.11465699 |
126 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.11143117 |
127 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.11007399 |
128 | Salmonella infection_Homo sapiens_hsa05132 | 0.10673438 |
129 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.10333690 |
130 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.10149163 |
131 | Prion diseases_Homo sapiens_hsa05020 | 0.06799721 |
132 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.06294298 |
133 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.05878479 |
134 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.05399701 |
135 | Cocaine addiction_Homo sapiens_hsa05030 | 0.02836950 |
136 | Morphine addiction_Homo sapiens_hsa05032 | 0.02222614 |