ARCHS4

Functional Annotation Prediction

Predicted biological processes (GO)

Rank	Gene Set	Z-score
1	viral transcription (GO:0019083)	8.44322909
2	translational termination (GO:0006415)	8.07819306
3	ribosomal small subunit biogenesis (GO:0042274)	8.00361859
4	ribosomal small subunit assembly (GO:0000028)	7.59778450
5	SRP-dependent cotranslational protein targeting to membrane (GO:0006614)	7.31306840
6	cotranslational protein targeting to membrane (GO:0006613)	7.25295368
7	protein targeting to ER (GO:0045047)	7.18907139
8	mitochondrial ATP synthesis coupled proton transport (GO:0042776)	6.96644273
9	translational elongation (GO:0006414)	6.90923258
10	establishment of protein localization to endoplasmic reticulum (GO:0072599)	6.87183557
11	protein localization to endoplasmic reticulum (GO:0070972)	6.79679197
12	* ATP synthesis coupled proton transport (GO:0015986)	6.45021341
13	* energy coupled proton transport, down electrochemical gradient (GO:0015985)	6.45021341
14	viral life cycle (GO:0019058)	6.35184917
15	cellular protein complex disassembly (GO:0043624)	6.30255072
16	maturation of SSU-rRNA (GO:0030490)	6.07843923
17	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)	6.05825984
18	ribosomal large subunit biogenesis (GO:0042273)	5.98670972
19	translational initiation (GO:0006413)	5.92479844
20	mitochondrial electron transport, NADH to ubiquinone (GO:0006120)	5.40589548
21	protein complex disassembly (GO:0043241)	5.38179427
22	translation (GO:0006412)	5.22840477
23	macromolecular complex disassembly (GO:0032984)	5.06658139
24	respiratory electron transport chain (GO:0022904)	5.00406337
25	electron transport chain (GO:0022900)	4.88858350
26	protein targeting to membrane (GO:0006612)	4.80286519
27	proteasome assembly (GO:0043248)	4.54709348
28	ribonucleoprotein complex biogenesis (GO:0022613)	4.44618861
29	nuclear-transcribed mRNA catabolic process (GO:0000956)	4.37235978
30	DNA deamination (GO:0045006)	4.33872277
31	establishment of integrated proviral latency (GO:0075713)	4.15784187
32	mRNA catabolic process (GO:0006402)	4.14418038
33	mitochondrial respiratory chain complex I assembly (GO:0032981)	4.10964802
34	NADH dehydrogenase complex assembly (GO:0010257)	4.10964802
35	mitochondrial respiratory chain complex I biogenesis (GO:0097031)	4.10964802
36	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)	4.03171559
37	cellular component biogenesis (GO:0044085)	4.02970047
38	protein complex biogenesis (GO:0070271)	4.00217579
39	termination of RNA polymerase III transcription (GO:0006386)	3.98580178
40	transcription elongation from RNA polymerase III promoter (GO:0006385)	3.98580178
41	peptidyl-histidine modification (GO:0018202)	3.86530224
42	protein neddylation (GO:0045116)	3.83721830
43	RNA catabolic process (GO:0006401)	3.76923211
44	GTP biosynthetic process (GO:0006183)	3.75837659
45	negative regulation of ubiquitin-protein transferase activity (GO:0051444)	3.75479784
46	negative regulation of ligase activity (GO:0051352)	3.75479784
47	oxidative phosphorylation (GO:0006119)	3.75115398
48	formation of translation preinitiation complex (GO:0001731)	3.74695968
49	establishment of protein localization to mitochondrial membrane (GO:0090151)	3.74595566
50	mitochondrial respiratory chain complex assembly (GO:0033108)	3.73957461
51	pyrimidine deoxyribonucleotide catabolic process (GO:0009223)	3.72736974
52	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00	3.71663101
53	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:	3.68379193
54	inner mitochondrial membrane organization (GO:0007007)	3.68075140
55	intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)	3.62949874
56	signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)	3.62949874
57	establishment of viral latency (GO:0019043)	3.59132539
58	signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)	3.57991085
59	signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)	3.57991085
60	signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)	3.57991085
61	regulation of cellular amino acid metabolic process (GO:0006521)	3.57891271
62	regulation of mitochondrial translation (GO:0070129)	3.56921184
63	rRNA processing (GO:0006364)	3.56142736
64	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)	3.55518402
65	chaperone-mediated protein transport (GO:0072321)	3.54028304
66	* ribonucleoside triphosphate biosynthetic process (GO:0009201)	3.51707219
67	nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)	3.50432839
68	sequestering of actin monomers (GO:0042989)	3.50421433
69	signal transduction involved in DNA integrity checkpoint (GO:0072401)	3.49315675
70	signal transduction involved in DNA damage checkpoint (GO:0072422)	3.49315675
71	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)	3.49006920
72	antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)	3.48396469
73	L-methionine biosynthetic process from methylthioadenosine (GO:0019509)	3.45227794
74	cytochrome complex assembly (GO:0017004)	3.43903945
75	signal transduction involved in cell cycle checkpoint (GO:0072395)	3.43900370
76	rRNA metabolic process (GO:0016072)	3.42411960
77	* hydrogen ion transmembrane transport (GO:1902600)	3.42280370
78	UTP biosynthetic process (GO:0006228)	3.40492610
79	establishment of protein localization to membrane (GO:0090150)	3.40007260
80	respiratory chain complex IV assembly (GO:0008535)	3.39014870
81	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0	3.38927396
82	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	3.37555899
83	aerobic respiration (GO:0009060)	3.36219016
84	7-methylguanosine mRNA capping (GO:0006370)	3.33812440
85	telomere maintenance via semi-conservative replication (GO:0032201)	3.31772707
86	RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)	3.28373971
87	tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)	3.28373971
88	protein targeting (GO:0006605)	3.27815451
89	RNA capping (GO:0036260)	3.27299731
90	7-methylguanosine RNA capping (GO:0009452)	3.27299731
91	protein targeting to mitochondrion (GO:0006626)	3.20795473
92	cullin deneddylation (GO:0010388)	3.17829511
93	* nucleoside triphosphate biosynthetic process (GO:0009142)	3.14756885
94	DNA strand elongation involved in DNA replication (GO:0006271)	3.14559016
95	deoxyribonucleoside monophosphate metabolic process (GO:0009162)	3.13929998
96	establishment of protein localization to mitochondrion (GO:0072655)	3.11808438
97	protein localization to mitochondrion (GO:0070585)	3.11424587
98	* purine ribonucleoside triphosphate biosynthetic process (GO:0009206)	3.10681522
99	pyrimidine nucleotide catabolic process (GO:0006244)	3.10360135
100	spliceosomal snRNP assembly (GO:0000387)	3.08879506
101	transcription-coupled nucleotide-excision repair (GO:0006283)	3.08831121
102	pseudouridine synthesis (GO:0001522)	3.06657473
103	pyrimidine nucleoside triphosphate metabolic process (GO:0009147)	3.05333805
104	guanosine-containing compound biosynthetic process (GO:1901070)	3.05004097
105	pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)	3.04909257
106	* purine nucleoside monophosphate biosynthetic process (GO:0009127)	3.04487759
107	* purine ribonucleoside monophosphate biosynthetic process (GO:0009168)	3.04487759
108	* purine nucleoside triphosphate biosynthetic process (GO:0009145)	3.03659805
109	establishment of protein localization to organelle (GO:0072594)	3.00707605
110	DNA strand elongation (GO:0022616)	3.00506894
111	positive regulation of ubiquitin-protein transferase activity (GO:0051443)	3.00467233
112	* proton transport (GO:0015992)	2.97859017
113	CTP metabolic process (GO:0046036)	2.95255400
114	CTP biosynthetic process (GO:0006241)	2.95255400
115	pyrimidine deoxyribonucleotide metabolic process (GO:0009219)	2.95131516
116	positive regulation of ligase activity (GO:0051351)	2.95088418
117	UTP metabolic process (GO:0046051)	2.94932644
118	base-excision repair, AP site formation (GO:0006285)	2.93787487
119	protein deneddylation (GO:0000338)	2.92855688
120	protein localization to membrane (GO:0072657)	2.91704065
121	* ATP biosynthetic process (GO:0006754)	2.91517953
122	mitochondrial transport (GO:0006839)	2.91454121
123	DNA damage response, signal transduction by p53 class mediator (GO:0030330)	2.91323679
124	* hydrogen transport (GO:0006818)	2.90752808
125	positive regulation of cell cycle arrest (GO:0071158)	2.89352192
126	intracellular protein transmembrane import (GO:0044743)	2.87006198
127	deoxyribonucleotide catabolic process (GO:0009264)	2.86148663
128	deoxyribonucleoside triphosphate metabolic process (GO:0009200)	2.84607729

Predicted upstream transcription factors (ChEA)

Rank	Gene Set	Z-score
1	SOX9_22984422_ChIP-ChIP_TESTIS_Rat	4.76167091
2	KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human	4.57698517
3	* MYC_18555785_ChIP-Seq_MESCs_Mouse	4.49115584
4	GABP_17652178_ChIP-ChIP_JURKAT_Human	4.35880270
5	EST1_17652178_ChIP-ChIP_JURKAT_Human	4.27365836
6	JARID1A_20064375_ChIP-Seq_MESCs_Mouse	3.86942007
7	ETS1_20019798_ChIP-Seq_JURKAT_Human	3.74303442
8	* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse	3.74102277
9	CREB1_15753290_ChIP-ChIP_HEK293T_Human	3.65393636
10	NOTCH1_17114293_ChIP-ChIP_T-ALL_Human	3.42755646
11	HCFC1_20581084_ChIP-Seq_MESCs_Mouse	3.38588672
12	* CHD1_19587682_ChIP-ChIP_MESCs_Mouse	3.22399947
13	* MYC_18358816_ChIP-ChIP_MESCs_Mouse	3.18464357
14	* MYC_19079543_ChIP-ChIP_MESCs_Mouse	3.05006960
15	HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human	2.98608717
16	E2F7_22180533_ChIP-Seq_HELA_Human	2.89756719
17	CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human	2.83665547
18	* MYC_19030024_ChIP-ChIP_MESCs_Mouse	2.79788838
19	ELF1_17652178_ChIP-ChIP_JURKAT_Human	2.74019387
20	XRN2_22483619_ChIP-Seq_HELA_Human	2.68551618
21	DCP1A_22483619_ChIP-Seq_HELA_Human	2.52980768
22	VDR_23849224_ChIP-Seq_CD4+_Human	2.45144524
23	* E2F1_18555785_ChIP-Seq_MESCs_Mouse	2.41127978
24	SRF_21415370_ChIP-Seq_HL-1_Mouse	2.26103569
25	* THAP11_20581084_ChIP-Seq_MESCs_Mouse	2.20310885
26	E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse	2.20287378
27	FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human	2.13906510
28	TTF2_22483619_ChIP-Seq_HELA_Human	2.13172878
29	PDX1_19855005_ChIP-ChIP_MIN6_Mouse	2.11391474
30	YY1_21170310_ChIP-Seq_MESCs_Mouse	2.09857054
31	FOXP3_21729870_ChIP-Seq_TREG_Human	2.09851204
32	CEBPB_24764292_ChIP-Seq_MC3T3_Mouse	2.08880268
33	ELK1_19687146_ChIP-ChIP_HELA_Human	2.05562515
34	NELFA_20434984_ChIP-Seq_ESCs_Mouse	1.98352780
35	HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse	1.95900218
36	SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse	1.91554302
37	E2F4_17652178_ChIP-ChIP_JURKAT_Human	1.88716133
38	ZFP42_18358816_ChIP-ChIP_MESCs_Mouse	1.80110091
39	TAL1_20887958_ChIP-Seq_HPC-7_Mouse	1.78878598
40	* GABP_19822575_ChIP-Seq_HepG2_Human	1.78147304
41	ELK1_22589737_ChIP-Seq_MCF10A_Human	1.76818110
42	MYBL2_22936984_ChIP-ChIP_MESCs_Mouse	1.63879956
43	FLI1_20887958_ChIP-Seq_HPC-7_Mouse	1.61871256
44	HOXB4_20404135_ChIP-ChIP_EML_Mouse	1.61754556
45	FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse	1.59001375
46	* POU5F1_18555785_ChIP-Seq_MESCs_Mouse	1.52596497
47	POU5F1_18358816_ChIP-ChIP_MESCs_Mouse	1.52001993
48	ERG_20887958_ChIP-Seq_HPC-7_Mouse	1.50319206
49	CEBPB_23403033_ChIP-Seq_LIVER_Mouse	1.45465897
50	NANOG_18555785_ChIP-Seq_MESCs_Mouse	1.43535428
51	DMRT1_21621532_ChIP-ChIP_FETAL_Ovary	1.36804439
52	KLF4_19030024_ChIP-ChIP_MESCs_Mouse	1.36668163
53	BCL3_23251550_ChIP-Seq_MUSCLE_Mouse	1.36643277
54	* CCND1_20090754_ChIP-ChIP_RETINA_Mouse	1.27686218
55	SPI1_22096565_ChIP-ChIP_GC-B_Mouse	1.26729444
56	ASH2L_23239880_ChIP-Seq_MESCs_Mouse	1.23903746
57	* ZFX_18555785_ChIP-Seq_MESCs_Mouse	1.21263734
58	MYCN_18555785_ChIP-Seq_MESCs_Mouse	1.19928456
59	* FOXP1_21924763_ChIP-Seq_HESCs_Human	1.19270163
60	TP63_19390658_ChIP-ChIP_HaCaT_Human	1.18877439
61	* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse	1.15709844
62	CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human	1.13813847
63	MYC_18940864_ChIP-ChIP_HL60_Human	1.13448134
64	FOXM1_23109430_ChIP-Seq_U2OS_Human	1.13441564
65	PPARG_19300518_ChIP-PET_3T3-L1_Mouse	1.10167816
66	* ESRRB_18555785_ChIP-Seq_MESCs_Mouse	1.09419187
67	SIN3B_21632747_ChIP-Seq_MESCs_Mouse	1.09082194
68	SFPI1_20887958_ChIP-Seq_HPC-7_Mouse	1.08208746
69	TET1_21451524_ChIP-Seq_MESCs_Mouse	1.06101437
70	TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse	1.05901078
71	E2F1_21310950_ChIP-Seq_MCF-7_Human	1.04741010
72	OCT4_18692474_ChIP-Seq_MEFs_Mouse	1.03968659
73	* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse	1.03610585
74	* KDM5A_27292631_Chip-Seq_BREAST_Human	1.03222501
75	* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse	1.02916799
76	IRF8_22096565_ChIP-ChIP_GC-B_Mouse	1.00833728
77	SOX2_16153702_ChIP-ChIP_HESCs_Human	1.00801845
78	CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human	1.00744768
79	HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse	0.99847233
80	TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat	0.99824762
81	* SOX2_18692474_ChIP-Seq_MEFs_Mouse	0.98280679
82	SOX2_18555785_ChIP-Seq_MESCs_Mouse	0.98169186
83	BP1_19119308_ChIP-ChIP_Hs578T_Human	0.96939745
84	PADI4_21655091_ChIP-ChIP_MCF-7_Human	0.96227651
85	CIITA_25753668_ChIP-Seq_RAJI_Human	0.95942634
86	SPI1_23547873_ChIP-Seq_NB4_Human	0.95396206
87	CTCF_26484167_Chip-Seq_Bcells_Mouse	0.94930384
88	* CTCF_18555785_ChIP-Seq_MESCs_Mouse	0.94580693
89	NOTCH1_21737748_ChIP-Seq_TLL_Human	0.94464722
90	SRY_22984422_ChIP-ChIP_TESTIS_Rat	0.93264228
91	HNF4A_19761587_ChIP-ChIP_CACO-2_Human	0.91412453
92	* SOX17_20123909_ChIP-Seq_XEN_Mouse	0.90355136
93	STAT1_20625510_ChIP-Seq_HELA_Human	0.89401684
94	MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse	0.88863662
95	CNOT3_19339689_ChIP-ChIP_MESCs_Mouse	0.88628585
96	NR4A2_19515692_ChIP-ChIP_MN9D_Mouse	0.87823170
97	CEBPA_23403033_ChIP-Seq_LIVER_Mouse	0.87657370
98	IRF1_19129219_ChIP-ChIP_H3396_Human	0.87498413
99	KLF4_18358816_ChIP-ChIP_MESCs_Mouse	0.86244214
100	RBPJ_21746931_ChIP-Seq_IB4-LCL_Human	0.84465143
101	ELF1_20517297_ChIP-Seq_JURKAT_Human	0.84276079
102	DACH1_20351289_ChIP-Seq_MDA-MB-231_Human	0.83888928
103	GFI1B_20887958_ChIP-Seq_HPC-7_Mouse	0.83278281
104	EBNA2_21746931_ChIP-Seq_IB4-LCL_Human	0.81761168
105	TFEB_21752829_ChIP-Seq_HELA_Human	0.81248409
106	TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse	0.80646091
107	YY1_22570637_ChIP-Seq_MALME-3M_Human	0.79840293
108	KLF2_18264089_ChIP-ChIP_MESCs_Mouse	0.78887244
109	KLF5_18264089_ChIP-ChIP_MESCs_Mouse	0.78887244
110	KLF4_18264089_ChIP-ChIP_MESCs_Mouse	0.78887244
111	ESR1_15608294_ChIP-ChIP_MCF-7_Human	0.78384293
112	BCL6_27268052_Chip-Seq_Bcells_Human	0.78072595
113	* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human	0.77472595
114	E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human	0.76876707
115	NANOG_16153702_ChIP-ChIP_HESCs_Human	0.75866110
116	MYCN_21190229_ChIP-Seq_SHEP-21N_Human	0.75824869
117	STAT3_1855785_ChIP-Seq_MESCs_Mouse	0.74406527
118	P68_20966046_ChIP-Seq_HELA_Human	0.73831442
119	SIN3A_21632747_ChIP-Seq_MESCs_Mouse	0.72245626

Predicted mouse phenotypes (MGI)

Rank	Gene Set	Z-score
1	MP0009379_abnormal_foot_pigmentation	5.64308077
2	MP0003693_abnormal_embryo_hatching	3.27705542
3	MP0003806_abnormal_nucleotide_metabolis	3.06364884
4	MP0004957_abnormal_blastocyst_morpholog	2.99130044
5	MP0003186_abnormal_redox_activity	2.87883556
6	MP0010030_abnormal_orbit_morphology	2.60076932
7	MP0001529_abnormal_vocalization	2.54075144
8	MP0006036_abnormal_mitochondrial_physio	2.49780522
9	MP0008932_abnormal_embryonic_tissue	2.49527098
10	MP0008057_abnormal_DNA_replication	2.42953210
11	MP0002653_abnormal_ependyma_morphology	2.18250270
12	MP0003077_abnormal_cell_cycle	2.15494829
13	MP0003136_yellow_coat_color	2.09757620
14	MP0008995_early_reproductive_senescence	2.04545945
15	MP0000749_muscle_degeneration	1.95439286
16	MP0005394_taste/olfaction_phenotype	1.92936669
17	MP0005499_abnormal_olfactory_system	1.92936669
18	MP0001905_abnormal_dopamine_level	1.88901020
19	MP0002837_dystrophic_cardiac_calcinosis	1.85417528
20	MP0006035_abnormal_mitochondrial_morpho	1.79014941
21	MP0005075_abnormal_melanosome_morpholog	1.76320853
22	MP0002148_abnormal_hypersensitivity_rea	1.75444405
23	MP0010094_abnormal_chromosome_stability	1.73781758
24	MP0002163_abnormal_gland_morphology	1.72905815
25	MP0002938_white_spotting	1.69866734
26	MP0004381_abnormal_hair_follicle	1.68939898
27	MP0002234_abnormal_pharynx_morphology	1.68478734
28	MP0002132_abnormal_respiratory_system	1.68174592
29	MP0003011_delayed_dark_adaptation	1.66889474
30	MP0003786_premature_aging	1.66851965
31	MP0004133_heterotaxia	1.66282613
32	MP0008058_abnormal_DNA_repair	1.65861495
33	MP0000372_irregular_coat_pigmentation	1.56187695
34	MP0002638_abnormal_pupillary_reflex	1.54166286
35	MP0009333_abnormal_splenocyte_physiolog	1.51514531
36	MP0000750_abnormal_muscle_regeneration	1.50185537
37	MP0005409_darkened_coat_color	1.49565527
38	MP0001346_abnormal_lacrimal_gland	1.49442077
39	MP0006292_abnormal_olfactory_placode	1.48314813
40	MP0004145_abnormal_muscle_electrophysio	1.47478525
41	MP0001727_abnormal_embryo_implantation	1.45022587
42	MP0003950_abnormal_plasma_membrane	1.43749260
43	MP0003718_maternal_effect	1.43557816
44	MP0005451_abnormal_body_composition	1.38150439
45	MP0003111_abnormal_nucleus_morphology	1.35725310
46	MP0003880_abnormal_central_pattern	1.34718096
47	MP0005330_cardiomyopathy	1.33235647
48	MP0003122_maternal_imprinting	1.31295946
49	MP0002822_catalepsy	1.30165091
50	MP0001853_heart_inflammation	1.28591484
51	MP0000049_abnormal_middle_ear	1.28258313
52	MP0003123_paternal_imprinting	1.27367354
53	MP0003567_abnormal_fetal_cardiomyocyte	1.27155145
54	MP0003941_abnormal_skin_development	1.25441883
55	MP0006072_abnormal_retinal_apoptosis	1.24490198
56	MP0002751_abnormal_autonomic_nervous	1.24334676
57	MP0000631_abnormal_neuroendocrine_gland	1.23282293
58	MP0005379_endocrine/exocrine_gland_phen	1.22998120
59	MP0001835_abnormal_antigen_presentation	1.21001057
60	MP0002095_abnormal_skin_pigmentation	1.14005054
61	MP0005408_hypopigmentation	1.13712319
62	MP0009785_altered_susceptibility_to	1.11873732
63	MP0004142_abnormal_muscle_tone	1.11248945
64	MP0003121_genomic_imprinting	1.09574230
65	MP0008007_abnormal_cellular_replicative	1.08624363
66	MP0008789_abnormal_olfactory_epithelium	1.08610600
67	MP0006276_abnormal_autonomic_nervous	1.07331650
68	MP0001485_abnormal_pinna_reflex	1.06371637
69	MP0002277_abnormal_respiratory_mucosa	1.05819673
70	MP0005671_abnormal_response_to	1.05499297
71	MP0000358_abnormal_cell_content/	1.05049326
72	MP0003315_abnormal_perineum_morphology	1.04173926
73	MP0002210_abnormal_sex_determination	1.03256998
74	MP0002736_abnormal_nociception_after	1.02825390
75	MP0001986_abnormal_taste_sensitivity	1.02648081
76	MP0005645_abnormal_hypothalamus_physiol	1.02060007
77	MP0005266_abnormal_metabolism	1.02019790
78	MP0003283_abnormal_digestive_organ	0.99439362
79	MP0001764_abnormal_homeostasis	0.96783424
80	MP0000685_abnormal_immune_system	0.96415840
81	MP0000026_abnormal_inner_ear	0.95886764
82	MP0003878_abnormal_ear_physiology	0.95177483
83	MP0005377_hearing/vestibular/ear_phenot	0.95177483
84	MP0003763_abnormal_thymus_physiology	0.94540424
85	MP0002249_abnormal_larynx_morphology	0.93237391
86	MP0002127_abnormal_cardiovascular_syste	0.92862575
87	MP0002102_abnormal_ear_morphology	0.92169452
88	MP0000678_abnormal_parathyroid_gland	0.91357801
89	MP0005171_absent_coat_pigmentation	0.91242150
90	MP0004084_abnormal_cardiac_muscle	0.91085629
91	MP0001286_abnormal_eye_development	0.90919631
92	MP0000313_abnormal_cell_death	0.90409905
93	MP0000490_abnormal_crypts_of	0.89703699
94	MP0005174_abnormal_tail_pigmentation	0.89476673
95	MP0003787_abnormal_imprinting	0.88587312
96	MP0005000_abnormal_immune_tolerance	0.88199283
97	MP0000920_abnormal_myelination	0.87878480
98	MP0001145_abnormal_male_reproductive	0.87454275
99	MP0005025_abnormal_response_to	0.86888157
100	MP0002697_abnormal_eye_size	0.86430572
101	MP0000762_abnormal_tongue_morphology	0.85620977
102	MP0002160_abnormal_reproductive_system	0.83696471
103	MP0001730_embryonic_growth_arrest	0.83570211
104	MP0003938_abnormal_ear_development	0.80845022
105	MP0008877_abnormal_DNA_methylation	0.80577647
106	MP0005646_abnormal_pituitary_gland	0.80540311
107	MP0000653_abnormal_sex_gland	0.80390225
108	MP0005084_abnormal_gallbladder_morpholo	0.80355110
109	MP0003646_muscle_fatigue	0.80243342
110	MP0004147_increased_porphyrin_level	0.80121619
111	MP0002722_abnormal_immune_system	0.78725239
112	MP0002106_abnormal_muscle_physiology	0.77487588
113	MP0002233_abnormal_nose_morphology	0.76639906
114	MP0005253_abnormal_eye_physiology	0.76317636
115	MP0001929_abnormal_gametogenesis	0.75610725
116	MP0005551_abnormal_eye_electrophysiolog	0.75489270
117	MP0001293_anophthalmia	0.74480068
118	MP0002752_abnormal_somatic_nervous	0.74435404
119	MP0002332_abnormal_exercise_endurance	0.74108986
120	MP0000566_synostosis	0.73950414
121	MP0009697_abnormal_copulation	0.73287675
122	MP0002405_respiratory_system_inflammati	0.72889757
123	MP0004215_abnormal_myocardial_fiber	0.72816723
124	MP0001968_abnormal_touch/_nociception	0.71997522
125	MP0006082_CNS_inflammation	0.71230423
126	MP0000689_abnormal_spleen_morphology	0.71217291
127	MP0002723_abnormal_immune_serum	0.71074175
128	MP0004036_abnormal_muscle_relaxation	0.71032332
129	MP0005391_vision/eye_phenotype	0.70970677
130	MP0000858_altered_metastatic_potential	0.70349395
131	MP0000613_abnormal_salivary_gland	0.69814423
132	MP0003137_abnormal_impulse_conducting	0.69413518
133	MP0003698_abnormal_male_reproductive	0.69082949
134	MP0005501_abnormal_skin_physiology	0.68963479
135	MP0000343_altered_response_to	0.68355065
136	MP0005195_abnormal_posterior_eye	0.68342021
137	MP0002019_abnormal_tumor_incidence	0.67747656
138	MP0001697_abnormal_embryo_size	0.67111146
139	MP0008872_abnormal_physiological_respon	0.66964456
140	MP0000778_abnormal_nervous_system	0.66591162
141	MP0001800_abnormal_humoral_immune	0.66319730
142	MP0002429_abnormal_blood_cell	0.66210465
143	MP0003937_abnormal_limbs/digits/tail_de	0.65843856
144	MP0000350_abnormal_cell_proliferation	0.65759416
145	MP0002420_abnormal_adaptive_immunity	0.65532215
146	MP0004742_abnormal_vestibular_system	0.64525267
147	MP0002557_abnormal_social/conspecific_i	0.63365057
148	MP0001963_abnormal_hearing_physiology	0.62947560
149	MP0002111_abnormal_tail_morphology	0.61665296
150	MP0002282_abnormal_trachea_morphology	0.61319155
151	MP0008875_abnormal_xenobiotic_pharmacok	0.61072644

Predicted human phenotypes

Rank	Gene Set	Z-score
1	Abnormality of cells of the erythroid lineage (HP:0012130)	7.29798076
2	Acute necrotizing encephalopathy (HP:0006965)	5.98953774
3	Abnormal number of erythroid precursors (HP:0012131)	5.90145149
4	Abnormal mitochondria in muscle tissue (HP:0008316)	5.36968900
5	Mitochondrial inheritance (HP:0001427)	5.31757019
6	Reticulocytopenia (HP:0001896)	5.21111771
7	Acute encephalopathy (HP:0006846)	4.86602675
8	Progressive macrocephaly (HP:0004481)	4.71428766
9	Macrocytic anemia (HP:0001972)	4.65578991
10	Hepatocellular necrosis (HP:0001404)	4.57148605
11	Increased CSF lactate (HP:0002490)	4.52494431
12	Decreased activity of mitochondrial respiratory chain (HP:0008972)	4.46917044
13	Abnormal activity of mitochondrial respiratory chain (HP:0011922)	4.46917044
14	Increased hepatocellular lipid droplets (HP:0006565)	4.46519702
15	Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)	4.30113213
16	Hepatic necrosis (HP:0002605)	4.19518479
17	Pallor (HP:0000980)	4.17709825
18	Renal Fanconi syndrome (HP:0001994)	4.15253092
19	Lipid accumulation in hepatocytes (HP:0006561)	4.08782992
20	Microvesicular hepatic steatosis (HP:0001414)	4.05709340
21	3-Methylglutaconic aciduria (HP:0003535)	3.96135880
22	Muscle abnormality related to mitochondrial dysfunction (HP:0003800)	3.94389017
23	Cerebral edema (HP:0002181)	3.72755351
24	Exercise intolerance (HP:0003546)	3.72333232
25	Increased intramyocellular lipid droplets (HP:0012240)	3.62445330
26	Aplasia/Hypoplasia of the sacrum (HP:0008517)	3.61252461
27	Exertional dyspnea (HP:0002875)	3.58758456
28	Abnormality of glycolysis (HP:0004366)	3.51290395
29	Increased serum pyruvate (HP:0003542)	3.51290395
30	Congenital nonbullous ichthyosiform erythroderma (HP:0007479)	3.39022668
31	Respiratory failure (HP:0002878)	3.36195870
32	Increased serum lactate (HP:0002151)	3.30604482
33	Leukodystrophy (HP:0002415)	3.25986358
34	Abnormal hemoglobin (HP:0011902)	3.24675024
35	Lactic acidosis (HP:0003128)	3.23273400
36	Increased muscle lipid content (HP:0009058)	3.12158604
37	Stenosis of the external auditory canal (HP:0000402)	3.00278409
38	Optic disc pallor (HP:0000543)	2.94777102
39	Parakeratosis (HP:0001036)	2.84035985
40	Cerebral hypomyelination (HP:0006808)	2.73885948
41	Respiratory difficulties (HP:0002880)	2.61506918
42	Congenital ichthyosiform erythroderma (HP:0007431)	2.52712462
43	Septo-optic dysplasia (HP:0100842)	2.50158235
44	Abnormality of renal resorption (HP:0011038)	2.46346139
45	Type I transferrin isoform profile (HP:0003642)	2.37850710
46	Pancreatic fibrosis (HP:0100732)	2.28226574
47	Sclerocornea (HP:0000647)	2.22983835
48	Hyperglycinemia (HP:0002154)	2.19788874
49	Aplastic anemia (HP:0001915)	2.18751709
50	Hyperphosphaturia (HP:0003109)	2.16953606
51	Myokymia (HP:0002411)	2.16684657
52	Abnormality of placental membranes (HP:0011409)	2.15844765
53	Amniotic constriction ring (HP:0009775)	2.15844765
54	Absent thumb (HP:0009777)	2.10335393
55	Pancreatic cysts (HP:0001737)	2.04188630
56	Multiple enchondromatosis (HP:0005701)	2.00819419
57	Rib fusion (HP:0000902)	2.00396855
58	Abnormality of urine glucose concentration (HP:0011016)	2.00027527
59	Glycosuria (HP:0003076)	2.00027527
60	True hermaphroditism (HP:0010459)	1.99612404
61	CNS demyelination (HP:0007305)	1.98091774
62	Maternal diabetes (HP:0009800)	1.97550233
63	Partial duplication of the phalanx of hand (HP:0009999)	1.96359871
64	Depressed nasal ridge (HP:0000457)	1.93932806
65	Trismus (HP:0000211)	1.92936446
66	Molar tooth sign on MRI (HP:0002419)	1.92395356
67	Abnormality of midbrain morphology (HP:0002418)	1.92395356
68	Breast hypoplasia (HP:0003187)	1.90076889
69	Absent septum pellucidum (HP:0001331)	1.87737539
70	Poor head control (HP:0002421)	1.85770289
71	Abnormal urine phosphate concentration (HP:0012599)	1.85723983
72	Abnormality of the anterior horn cell (HP:0006802)	1.84593408
73	Degeneration of anterior horn cells (HP:0002398)	1.84593408
74	Birth length less than 3rd percentile (HP:0003561)	1.84032129
75	Progressive muscle weakness (HP:0003323)	1.83703142
76	Emotional lability (HP:0000712)	1.83279525
77	11 pairs of ribs (HP:0000878)	1.82835750
78	Dicarboxylic aciduria (HP:0003215)	1.82199630
79	Abnormality of dicarboxylic acid metabolism (HP:0010995)	1.82199630
80	Aplasia/hypoplasia of the uterus (HP:0008684)	1.80599459
81	Congenital, generalized hypertrichosis (HP:0004540)	1.80102791
82	Abnormality of the labia minora (HP:0012880)	1.80019297
83	Muscle fiber atrophy (HP:0100295)	1.78971397
84	Type 2 muscle fiber atrophy (HP:0003554)	1.78885243
85	Lethargy (HP:0001254)	1.77345577
86	Abnormality of secondary sexual hair (HP:0009888)	1.77124067
87	Abnormality of the axillary hair (HP:0100134)	1.77124067
88	Rough bone trabeculation (HP:0100670)	1.74026967
89	Methylmalonic aciduria (HP:0012120)	1.71898815
90	Hypoplasia of the radius (HP:0002984)	1.70883546
91	Oral leukoplakia (HP:0002745)	1.70004863
92	Asplenia (HP:0001746)	1.69495341
93	Generalized aminoaciduria (HP:0002909)	1.69371033
94	Medial flaring of the eyebrow (HP:0010747)	1.68693401
95	Rhabdomyolysis (HP:0003201)	1.68555663
96	Hyperglycinuria (HP:0003108)	1.68147528
97	Testicular atrophy (HP:0000029)	1.67438523
98	Partial duplication of thumb phalanx (HP:0009944)	1.66285184
99	Mesangial abnormality (HP:0001966)	1.66231110
100	Anophthalmia (HP:0000528)	1.65341308
101	Concave nail (HP:0001598)	1.62657693
102	X-linked dominant inheritance (HP:0001423)	1.62324186
103	Nephronophthisis (HP:0000090)	1.59799384
104	Aplasia/Hypoplasia of the uvula (HP:0010293)	1.59224375
105	Meckel diverticulum (HP:0002245)	1.58911852
106	Renal tubular dysfunction (HP:0000124)	1.58902975
107	Pancytopenia (HP:0001876)	1.58481902
108	Anencephaly (HP:0002323)	1.56946217
109	Blindness (HP:0000618)	1.56115511
110	Triphalangeal thumb (HP:0001199)	1.55374652
111	Abnormality of the ileum (HP:0001549)	1.54473726
112	Horseshoe kidney (HP:0000085)	1.54373928
113	Duplication of thumb phalanx (HP:0009942)	1.53106120
114	Gout (HP:0001997)	1.53040010
115	Abnormality of reticulocytes (HP:0004312)	1.52521621
116	Premature graying of hair (HP:0002216)	1.51474874
117	Methylmalonic acidemia (HP:0002912)	1.50448803
118	Carpal bone hypoplasia (HP:0001498)	1.50259590
119	Aplasia/Hypoplasia of the spleen (HP:0010451)	1.50014536
120	Aplasia/Hypoplasia involving the musculature (HP:0001460)	1.49758328
121	Increased IgM level (HP:0003496)	1.49204128
122	Reduced antithrombin III activity (HP:0001976)	1.47968217
123	Palpitations (HP:0001962)	1.47649371
124	Petechiae (HP:0000967)	1.47473444
125	Colon cancer (HP:0003003)	1.47325980
126	Cleft eyelid (HP:0000625)	1.46768406
127	Hypoplastic heart (HP:0001961)	1.46709511
128	Abnormal lung lobation (HP:0002101)	1.44968210
129	Abnormal protein glycosylation (HP:0012346)	1.44501375
130	Abnormal glycosylation (HP:0012345)	1.44501375
131	Abnormal isoelectric focusing of serum transferrin (HP:0003160)	1.44501375
132	Abnormal protein N-linked glycosylation (HP:0012347)	1.44501375

Predicted kinase interactions (KEA)

Rank	Gene Set	Z-score
1	VRK2	7.60464181
2	NME2	5.23473294
3	BUB1	5.06982855
4	EIF2AK1	2.81812899
5	TAF1	2.61155589
6	MST4	2.58143693
7	PIM2	2.56540307
8	EIF2AK3	2.55371386
9	PBK	2.48809166
10	STK16	2.46150795
11	VRK1	2.40611683
12	TESK2	2.25624882
13	WEE1	2.15025791
14	RPS6KB2	2.01255220
15	NUAK1	1.99974485
16	NME1	1.89888950
17	MYLK	1.65172218
18	TLK1	1.60437389
19	ILK	1.57508821
20	SRPK1	1.55547881
21	BCKDK	1.36790205
22	EPHB2	1.36246007
23	NEK1	1.35368984
24	LIMK1	1.34257354
25	PLK4	1.33159398
26	ARAF	1.30178315
27	MKNK1	1.24829649
28	STK39	1.24207192
29	MUSK	1.23947566
30	CDK19	1.21599719
31	KDR	1.21440873
32	MAPK15	1.20718692
33	PASK	1.20243166
34	SMG1	1.14310601
35	DYRK2	1.11708720
36	PLK3	1.11669324
37	ACVR1B	1.11469082
38	UHMK1	1.11399074
39	MAP4K2	1.10828694
40	ADRBK2	1.10470329
41	CHEK2	1.08704754
42	LRRK2	1.06844711
43	BCR	1.06067831
44	GRK7	1.03273007
45	ABL2	1.01443979
46	OBSCN	1.00291965
47	TESK1	0.99707495
48	CDK7	0.99355477
49	MAPKAPK5	0.99044333
50	ATR	0.97628837
51	AURKA	0.91844737
52	RPS6KA5	0.91827533
53	BRSK2	0.89454629
54	CDC7	0.88757325
55	PAK1	0.87592965
56	IRAK4	0.86637855
57	WNK3	0.86104103
58	AURKB	0.84994691
59	MAPKAPK3	0.82519153
60	EIF2AK2	0.81465770
61	TGFBR1	0.81124110
62	IRAK3	0.80716286
63	BLK	0.79891229
64	MAP3K11	0.78440265
65	BMPR1B	0.77540474
66	STK4	0.74323918
67	DAPK1	0.74186869
68	PLK1	0.73029530
69	CSNK2A1	0.72896862
70	DYRK3	0.71426710
71	BRSK1	0.71370218
72	NEK2	0.70259560
73	CDK8	0.70151807
74	MAP2K7	0.69697947
75	IKBKB	0.69617085
76	CSNK1G1	0.67968803
77	CSNK2A2	0.65652717
78	OXSR1	0.65230530
79	BRAF	0.63234258
80	DAPK3	0.61473629
81	MAP4K1	0.60297400
82	RPS6KA6	0.59134072
83	WNK4	0.58523155
84	RPS6KC1	0.57872070
85	RPS6KL1	0.57872070
86	PAK4	0.57509742
87	CLK1	0.56319598
88	CSNK1G2	0.56059457
89	EPHA4	0.55885214
90	ROCK2	0.54687484
91	PDK2	0.52068200
92	MAP3K3	0.50317279
93	STK24	0.48929225
94	PHKG1	0.47661234
95	PHKG2	0.47661234
96	BTK	0.47097437
97	RPS6KA4	0.46750723
98	MAP3K12	0.46382326
99	CSNK1A1L	0.46361402
100	CSNK1G3	0.45298822
101	TEC	0.45073546
102	TNIK	0.44836736
103	YES1	0.44557058
104	GRK6	0.44236008
105	PINK1	0.44101776
106	LYN	0.43611183
107	PRKCG	0.43031823
108	CCNB1	0.43019893
109	PIM1	0.42878656
110	FLT3	0.42527999
111	MAPKAPK2	0.41757271
112	ADRBK1	0.41473439
113	IRAK2	0.41458809
114	PIK3CG	0.41390600
115	DYRK1B	0.41332110
116	PRKCI	0.40862397
117	GRK5	0.40452918
118	INSRR	0.40423819
119	NLK	0.39900064
120	CDK11A	0.39844149
121	GRK1	0.39378103
122	PRKCD	0.39168945
123	MAP2K2	0.38719958
124	MKNK2	0.37661446
125	CSNK1A1	0.37563363
126	IRAK1	0.37461616
127	ZAK	0.36996592
128	CHEK1	0.36116840
129	TTK	0.35516559
130	TIE1	0.32749849
131	CDK2	0.29177190
132	AKT2	0.28176915
133	CDK3	0.28098838
134	CDK15	0.28067139
135	CAMK1	0.27837569
136	PRKACA	0.27788721
137	MAP3K4	0.27633689
138	CSNK1E	0.27103607
139	CDK14	0.26230177

Predicted pathways (KEGG)

Rank	Gene Set	Z-score
1	Ribosome_Homo sapiens_hsa03010	6.65520457
2	* Oxidative phosphorylation_Homo sapiens_hsa00190	4.41421172
3	Proteasome_Homo sapiens_hsa03050	4.27239266
4	Parkinsons disease_Homo sapiens_hsa05012	3.93266135
5	RNA polymerase_Homo sapiens_hsa03020	3.47224516
6	Protein export_Homo sapiens_hsa03060	2.87576357
7	Huntingtons disease_Homo sapiens_hsa05016	2.80655525
8	DNA replication_Homo sapiens_hsa03030	2.79176309
9	Alzheimers disease_Homo sapiens_hsa05010	2.72500298
10	Mismatch repair_Homo sapiens_hsa03430	2.59136703
11	Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932	2.51401532
12	Spliceosome_Homo sapiens_hsa03040	2.21711703
13	Pyrimidine metabolism_Homo sapiens_hsa00240	2.12560024
14	Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008	1.98207043
15	Homologous recombination_Homo sapiens_hsa03440	1.94061877
16	Nucleotide excision repair_Homo sapiens_hsa03420	1.87480503
17	Base excision repair_Homo sapiens_hsa03410	1.68977704
18	Terpenoid backbone biosynthesis_Homo sapiens_hsa00900	1.66356126
19	Cardiac muscle contraction_Homo sapiens_hsa04260	1.66329040
20	Fatty acid elongation_Homo sapiens_hsa00062	1.53742880
21	Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623	1.46726915
22	RNA transport_Homo sapiens_hsa03013	1.31782703
23	Basal transcription factors_Homo sapiens_hsa03022	1.20852070
24	RNA degradation_Homo sapiens_hsa03018	1.20777693
25	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563	1.18414066
26	Folate biosynthesis_Homo sapiens_hsa00790	1.12888313
27	Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130	1.11591932
28	Purine metabolism_Homo sapiens_hsa00230	1.06947475
29	Non-homologous end-joining_Homo sapiens_hsa03450	1.06842616
30	Glutathione metabolism_Homo sapiens_hsa00480	1.02214672
31	Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970	1.00230824
32	One carbon pool by folate_Homo sapiens_hsa00670	0.98580598
33	Steroid biosynthesis_Homo sapiens_hsa00100	0.95682449
34	Fanconi anemia pathway_Homo sapiens_hsa03460	0.93980548
35	Sulfur metabolism_Homo sapiens_hsa00920	0.85804793
36	Cell cycle_Homo sapiens_hsa04110	0.80705068
37	Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072	0.79365092
38	Citrate cycle (TCA cycle)_Homo sapiens_hsa00020	0.75339792
39	Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860	0.74699107
40	Arachidonic acid metabolism_Homo sapiens_hsa00590	0.74618632
41	Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520	0.73583288
42	* Metabolic pathways_Homo sapiens_hsa01100	0.72636401
43	Butanoate metabolism_Homo sapiens_hsa00650	0.72119170
44	Basal cell carcinoma_Homo sapiens_hsa05217	0.65031510
45	Glycine, serine and threonine metabolism_Homo sapiens_hsa00260	0.63829710
46	Epstein-Barr virus infection_Homo sapiens_hsa05169	0.63588521
47	Arginine and proline metabolism_Homo sapiens_hsa00330	0.61627573
48	Phenylalanine metabolism_Homo sapiens_hsa00360	0.60917694
49	Sulfur relay system_Homo sapiens_hsa04122	0.59826377
50	Allograft rejection_Homo sapiens_hsa05330	0.57733578
51	Graft-versus-host disease_Homo sapiens_hsa05332	0.55195381
52	Pathogenic Escherichia coli infection_Homo sapiens_hsa05130	0.53976063
53	Linoleic acid metabolism_Homo sapiens_hsa00591	0.53734067
54	Tyrosine metabolism_Homo sapiens_hsa00350	0.53399651
55	SNARE interactions in vesicular transport_Homo sapiens_hsa04130	0.52980079
56	Carbon metabolism_Homo sapiens_hsa01200	0.48243763
57	Vibrio cholerae infection_Homo sapiens_hsa05110	0.47488803
58	Biosynthesis of amino acids_Homo sapiens_hsa01230	0.46444059
59	Sphingolipid metabolism_Homo sapiens_hsa00600	0.46153703
60	Drug metabolism - cytochrome P450_Homo sapiens_hsa00982	0.45240352
61	p53 signaling pathway_Homo sapiens_hsa04115	0.44574233
62	Nitrogen metabolism_Homo sapiens_hsa00910	0.42326912
63	Tryptophan metabolism_Homo sapiens_hsa00380	0.41767686
64	Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980	0.41478174
65	Ether lipid metabolism_Homo sapiens_hsa00565	0.41114853
66	Cysteine and methionine metabolism_Homo sapiens_hsa00270	0.41087303
67	Asthma_Homo sapiens_hsa05310	0.40130457
68	Primary immunodeficiency_Homo sapiens_hsa05340	0.39016486
69	Selenocompound metabolism_Homo sapiens_hsa00450	0.38802280
70	Systemic lupus erythematosus_Homo sapiens_hsa05322	0.38235712
71	Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760	0.37222797
72	Histidine metabolism_Homo sapiens_hsa00340	0.36962034
73	Pyruvate metabolism_Homo sapiens_hsa00620	0.35169609
74	Peroxisome_Homo sapiens_hsa04146	0.34020953
75	Pentose phosphate pathway_Homo sapiens_hsa00030	0.33659959
76	2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210	0.33569165
77	Autoimmune thyroid disease_Homo sapiens_hsa05320	0.32999873
78	Phototransduction_Homo sapiens_hsa04744	0.32527544
79	Pentose and glucuronate interconversions_Homo sapiens_hsa00040	0.31978526
80	Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280	0.31928069
81	Intestinal immune network for IgA production_Homo sapiens_hsa04672	0.31833874
82	Propanoate metabolism_Homo sapiens_hsa00640	0.31708245
83	Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010	0.31313423
84	Fatty acid degradation_Homo sapiens_hsa00071	0.30943527
85	Cyanoamino acid metabolism_Homo sapiens_hsa00460	0.30055024
86	Rheumatoid arthritis_Homo sapiens_hsa05323	0.29871552
87	alpha-Linolenic acid metabolism_Homo sapiens_hsa00592	0.29314057
88	beta-Alanine metabolism_Homo sapiens_hsa00410	0.28781994
89	Chemical carcinogenesis_Homo sapiens_hsa05204	0.27429950
90	Drug metabolism - other enzymes_Homo sapiens_hsa00983	0.26882513
91	Fatty acid metabolism_Homo sapiens_hsa01212	0.26349330
92	Other glycan degradation_Homo sapiens_hsa00511	0.26058209
93	Galactose metabolism_Homo sapiens_hsa00052	0.25568517
94	mRNA surveillance pathway_Homo sapiens_hsa03015	0.25264765
95	Collecting duct acid secretion_Homo sapiens_hsa04966	0.24529382
96	Herpes simplex infection_Homo sapiens_hsa05168	0.22463642
97	Phagosome_Homo sapiens_hsa04145	0.21004929
98	Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400	0.19615741
99	Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040	0.19482066
100	Fructose and mannose metabolism_Homo sapiens_hsa00051	0.18523958
101	Ubiquitin mediated proteolysis_Homo sapiens_hsa04120	0.18166208
102	Vitamin digestion and absorption_Homo sapiens_hsa04977	0.17585786
103	Maturity onset diabetes of the young_Homo sapiens_hsa04950	0.16977522
104	Fat digestion and absorption_Homo sapiens_hsa04975	0.16545922
105	Legionellosis_Homo sapiens_hsa05134	0.16502553
106	Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060	0.15308487
107	Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250	0.13737835
108	Regulation of autophagy_Homo sapiens_hsa04140	0.13728841
109	Retinol metabolism_Homo sapiens_hsa00830	0.12340789
110	Caffeine metabolism_Homo sapiens_hsa00232	0.11892369
111	Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630	0.11713416
112	Primary bile acid biosynthesis_Homo sapiens_hsa00120	0.10728683
113	Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770	0.10689899
114	Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321	0.10193873
115	Hematopoietic cell lineage_Homo sapiens_hsa04640	0.09929735
116	Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080	0.09822585
117	Vitamin B6 metabolism_Homo sapiens_hsa00750	0.08781654
118	Viral myocarditis_Homo sapiens_hsa05416	0.08357980
119	Shigellosis_Homo sapiens_hsa05131	0.08174102
120	Antigen processing and presentation_Homo sapiens_hsa04612	0.06999391
121	Hedgehog signaling pathway_Homo sapiens_hsa04340	0.06449717
122	N-Glycan biosynthesis_Homo sapiens_hsa00510	0.05721312

ATP5G2

Functional Annotation Prediction

Predicted biological processes (GO)

Predicted upstream transcription factors (ChEA)

Predicted mouse phenotypes (MGI)

Predicted human phenotypes

Predicted kinase interactions (KEA)

Predicted pathways (KEGG)

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