ATP6V0D2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G7.73142120
2neutrophil activation involved in immune response (GO:0002283)6.94142400
3modulation by symbiont of host immune response (GO:0052553)6.20756706
4positive regulation by symbiont of host defense response (GO:0052509)6.20756706
5modulation by symbiont of host defense response (GO:0052031)6.20756706
6modulation by organism of immune response of other organism involved in symbiotic interaction (GO:006.20756706
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:06.20756706
8positive regulation by organism of defense response of other organism involved in symbiotic interact6.20756706
9macrophage activation involved in immune response (GO:0002281)5.34986647
10respiratory burst (GO:0045730)5.23408178
11hydrogen peroxide biosynthetic process (GO:0050665)4.98808863
12oligosaccharide catabolic process (GO:0009313)4.93322847
13granulocyte activation (GO:0036230)4.78610573
14superoxide anion generation (GO:0042554)4.61814086
15regulation of interferon-beta biosynthetic process (GO:0045357)4.60130599
16positive regulation of interleukin-8 biosynthetic process (GO:0045416)4.55305912
17amino sugar catabolic process (GO:0046348)4.53539833
18positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)4.47799459
19glycosphingolipid catabolic process (GO:0046479)4.47775050
20neutrophil activation (GO:0042119)4.44240581
21reactive oxygen species biosynthetic process (GO:1903409)4.38688617
22response to peptidoglycan (GO:0032494)4.33151666
23production of molecular mediator involved in inflammatory response (GO:0002532)4.25695292
24positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610814.20178191
25positive regulation of interferon-alpha production (GO:0032727)4.18476964
26phagocytosis, recognition (GO:0006910)4.17474675
27myeloid cell activation involved in immune response (GO:0002275)4.15355525
28detection of molecule of bacterial origin (GO:0032490)4.11932787
29immunoglobulin mediated immune response (GO:0016064)4.09194263
30ceramide catabolic process (GO:0046514)4.03818067
31regulation of mononuclear cell migration (GO:0071675)4.02360355
32lipopolysaccharide-mediated signaling pathway (GO:0031663)4.02059332
33glycolipid catabolic process (GO:0019377)4.01347733
34response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.00903811
35response to host immune response (GO:0052572)4.00903811
36positive regulation of mast cell activation (GO:0033005)3.93535365
37regulation of interferon-alpha production (GO:0032647)3.90204493
38tryptophan catabolic process (GO:0006569)3.85090006
39indole-containing compound catabolic process (GO:0042436)3.85090006
40indolalkylamine catabolic process (GO:0046218)3.85090006
41wound healing, spreading of epidermal cells (GO:0035313)3.84120588
42cellular response to zinc ion (GO:0071294)3.82502738
43positive regulation of heat generation (GO:0031652)3.81269325
44positive regulation of mast cell degranulation (GO:0043306)3.81218968
45positive regulation of mast cell activation involved in immune response (GO:0033008)3.81218968
46eosinophil chemotaxis (GO:0048245)3.80499120
47regulation of cholesterol storage (GO:0010885)3.79952677
48negative regulation of interleukin-12 production (GO:0032695)3.75466032
49positive regulation of macrophage cytokine production (GO:0060907)3.74836151
50macrophage activation (GO:0042116)3.71743678
51* phagosome maturation (GO:0090382)3.67070887
52positive regulation of chemokine biosynthetic process (GO:0045080)3.66212321
53regulation of syncytium formation by plasma membrane fusion (GO:0060142)3.66050676
54negative regulation of nitric oxide biosynthetic process (GO:0045019)3.60816774
55positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.59859297
56negative regulation of interleukin-17 production (GO:0032700)3.56415669
57natural killer cell mediated immunity (GO:0002228)3.54432099
58natural killer cell mediated cytotoxicity (GO:0042267)3.54432099
59kynurenine metabolic process (GO:0070189)3.52063124
60positive regulation of cellular amide metabolic process (GO:0034250)3.50716872
61regulation of mast cell degranulation (GO:0043304)3.50085356
62response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.47973101
63response to host (GO:0075136)3.47973101
64response to host defenses (GO:0052200)3.47973101
65microglial cell activation (GO:0001774)3.47967950
66regulation of mast cell activation (GO:0033003)3.46066801
67negative regulation of interleukin-1 beta production (GO:0032691)3.45848415
68regulation of chronic inflammatory response (GO:0002676)3.39229765
69glucosamine-containing compound catabolic process (GO:1901072)3.37526475
70regulation of vitamin D biosynthetic process (GO:0060556)3.37018019
71regulation of heat generation (GO:0031650)3.34348992
72eosinophil migration (GO:0072677)3.33949976
73platelet dense granule organization (GO:0060155)3.32348080
74positive regulation of T-helper 1 type immune response (GO:0002827)3.32148711
75negative regulation of mast cell activation (GO:0033004)3.32120650
76positive regulation of leukocyte degranulation (GO:0043302)3.28172059
77positive regulation of monocyte chemotaxis (GO:0090026)3.27519472
78positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.27519407
79regulation of mast cell activation involved in immune response (GO:0033006)3.25960220
80aldehyde catabolic process (GO:0046185)3.25506133
81regulation of fever generation (GO:0031620)3.25400719
82protein K11-linked deubiquitination (GO:0035871)3.25306711
83positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.24311937
84membrane lipid catabolic process (GO:0046466)3.23161997
85cellular response to thyroid hormone stimulus (GO:0097067)3.22502032
86cellular response to ATP (GO:0071318)3.21367617
87sphingolipid catabolic process (GO:0030149)3.20332522
88positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.19703884
89low-density lipoprotein particle clearance (GO:0034383)3.19590720
90monocyte chemotaxis (GO:0002548)3.19071861
91keratan sulfate catabolic process (GO:0042340)3.18611689
92positive regulation of antigen processing and presentation (GO:0002579)3.18514067
93positive regulation of interferon-beta production (GO:0032728)3.15485569
94regulation of B cell receptor signaling pathway (GO:0050855)3.14278332
95positive regulation of prostaglandin secretion (GO:0032308)3.12632327
96tryptophan metabolic process (GO:0006568)3.12588724
97N-acetylneuraminate metabolic process (GO:0006054)3.11593693
98vitamin D metabolic process (GO:0042359)3.09482909
99regulation of interleukin-8 biosynthetic process (GO:0045414)3.07716594
100tooth mineralization (GO:0034505)3.06847978
101* energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.06388724
102* ATP hydrolysis coupled proton transport (GO:0015991)3.06388724
103defense response to protozoan (GO:0042832)3.06166205
104intracellular pH reduction (GO:0051452)3.06122349
105myeloid leukocyte activation (GO:0002274)3.04868127
106positive regulation of osteoclast differentiation (GO:0045672)3.02337618
107detection of chemical stimulus involved in sensory perception of smell (GO:0050911)3.01846854
108detection of external biotic stimulus (GO:0098581)3.01195301
109myeloid dendritic cell differentiation (GO:0043011)3.00935828
110cellular biogenic amine catabolic process (GO:0042402)2.98468164
111amine catabolic process (GO:0009310)2.98468164
112leukocyte mediated cytotoxicity (GO:0001909)2.96824672
113indolalkylamine metabolic process (GO:0006586)2.95699087
114B cell mediated immunity (GO:0019724)2.95364376
115negative regulation of lipid storage (GO:0010888)2.94557687
116regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.94331703
117negative regulation of interleukin-1 production (GO:0032692)2.92653638
118regulation of chemokine biosynthetic process (GO:0045073)2.90923862
119regulation of cytokine secretion involved in immune response (GO:0002739)2.90804814
120regulation of macrophage cytokine production (GO:0010935)2.90270099
121neutrophil chemotaxis (GO:0030593)2.87421193
122positive regulation of interleukin-6 production (GO:0032755)2.87027219
123ganglioside metabolic process (GO:0001573)2.86521538
124myeloid dendritic cell activation (GO:0001773)2.85911707
125regulation of leukocyte degranulation (GO:0043300)2.85775500
126regulation of T-helper 1 type immune response (GO:0002825)2.81430867
127response to muramyl dipeptide (GO:0032495)2.80812824
128neutrophil migration (GO:1990266)2.80710103
129positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.80490582
130regulation of myeloid leukocyte mediated immunity (GO:0002886)2.80127730
131leukocyte aggregation (GO:0070486)2.79384416
132T-helper 1 type immune response (GO:0042088)2.79072208
133pH reduction (GO:0045851)2.79001937
134positive regulation of T-helper cell differentiation (GO:0045624)2.78200893
135negative regulation of myeloid cell apoptotic process (GO:0033033)2.76332057
136regulation of prostaglandin secretion (GO:0032306)2.75312155
137response to thyroid hormone (GO:0097066)2.74918883
138positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.74657291
139positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.74231713
140positive regulation of lipid storage (GO:0010884)2.71969790
141regulation of monocyte chemotaxis (GO:0090025)2.71541379
142superoxide metabolic process (GO:0006801)2.71240932
143positive regulation of gamma-delta T cell activation (GO:0046645)2.71013162
144regulation of T-helper 1 cell differentiation (GO:0045625)2.70442060
145fat-soluble vitamin biosynthetic process (GO:0042362)2.69934278
146negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.69356513
147negative regulation of T-helper cell differentiation (GO:0045623)2.69356513
148lytic vacuole organization (GO:0080171)2.66683205
149lysosome organization (GO:0007040)2.66683205
150macrophage chemotaxis (GO:0048246)2.66290282
151regulation of heterotypic cell-cell adhesion (GO:0034114)2.65493495
152positive regulation of chemokine production (GO:0032722)2.64860321
153positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.63889021
154regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.61311847
155positive regulation of calcium ion import (GO:0090280)2.56529609
156negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.55317165
157response to lipoprotein particle (GO:0055094)2.51552838
158neuromuscular process controlling posture (GO:0050884)2.49473446
159DNA deamination (GO:0045006)2.49111982
160branching involved in labyrinthine layer morphogenesis (GO:0060670)2.48577224
161regulation of inflammatory response to antigenic stimulus (GO:0002861)2.48466281
162sphingosine metabolic process (GO:0006670)2.48264940
163negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.48094710
164regulation of T-helper 2 cell differentiation (GO:0045628)2.47159248
165positive regulation of defense response to virus by host (GO:0002230)2.46570160
166vitamin biosynthetic process (GO:0009110)2.46041687
167regulation of T-helper cell differentiation (GO:0045622)2.45810841
168behavioral response to nicotine (GO:0035095)2.43554715
169response to xenobiotic stimulus (GO:0009410)2.42948786
170regulation of macrophage derived foam cell differentiation (GO:0010743)2.41099703
171positive regulation of NF-kappaB import into nucleus (GO:0042346)2.40721715
172positive regulation of toll-like receptor signaling pathway (GO:0034123)2.40607756
173regulation of vitamin metabolic process (GO:0030656)2.39019126

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human8.01845535
2IRF8_21731497_ChIP-ChIP_J774_Mouse6.98779180
3IRF8_22096565_ChIP-ChIP_GC-B_Human6.34328350
4Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse4.83098424
5IRF8_27001747_Chip-Seq_BMDM_Mouse4.41799452
6SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.21022377
7NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.82679587
8IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.27738499
9MYB_21317192_ChIP-Seq_ERMYB_Mouse3.13087624
10VDR_22108803_ChIP-Seq_LS180_Human3.10815445
11MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.07276299
12ZNF274_21170338_ChIP-Seq_K562_Hela2.97454272
13IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.85002544
14RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.83012767
15FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.73447349
16STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.66872135
17STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.30819319
18NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.27106178
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.26305993
20SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.20365946
21BRD4_27068464_Chip-Seq_AML-cells_Mouse2.12941941
22* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.11533696
23ZFP57_27257070_Chip-Seq_ESCs_Mouse2.02153783
24* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.98869953
25SPI1_23547873_ChIP-Seq_NB4_Human1.91908922
26VDR_24787735_ChIP-Seq_THP-1_Human1.89967864
27IGF1R_20145208_ChIP-Seq_DFB_Human1.87865898
28* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.83773233
29CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.81357954
30* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.79679652
31STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.79447122
32THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.78182155
33GBX2_23144817_ChIP-Seq_PC3_Human1.76971287
34EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.71914051
35PU_27001747_Chip-Seq_BMDM_Mouse1.71741310
36FLI1_27457419_Chip-Seq_LIVER_Mouse1.70893988
37NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.59730673
38PCGF2_27294783_Chip-Seq_ESCs_Mouse1.51345165
39NRF2_20460467_ChIP-Seq_MEFs_Mouse1.50676201
40NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.50676201
41SPI1_23127762_ChIP-Seq_K562_Human1.50273511
42RUNX_20019798_ChIP-Seq_JUKART_Human1.48682138
43* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.46114263
44RUNX1_22412390_ChIP-Seq_EML_Mouse1.45687415
45EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.45140393
46CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.45086171
47NOTCH1_21737748_ChIP-Seq_TLL_Human1.44764500
48ER_23166858_ChIP-Seq_MCF-7_Human1.44221574
49RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.43850445
50STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.43107643
51VDR_24763502_ChIP-Seq_THP-1_Human1.42856435
52P300_19829295_ChIP-Seq_ESCs_Human1.42682164
53UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.40552750
54CTBP1_25329375_ChIP-Seq_LNCAP_Human1.39986696
55POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.38998271
56TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38998271
57BCAT_22108803_ChIP-Seq_LS180_Human1.38845007
58HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.38546677
59PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.37289567
60VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.36668732
61NANOG_19829295_ChIP-Seq_ESCs_Human1.34905268
62SOX2_19829295_ChIP-Seq_ESCs_Human1.34905268
63POU3F2_20337985_ChIP-ChIP_501MEL_Human1.34275011
64SUZ12_27294783_Chip-Seq_NPCs_Mouse1.33543379
65CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.33325060
66AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32739123
67EZH2_27294783_Chip-Seq_NPCs_Mouse1.31430633
68GATA2_21666600_ChIP-Seq_HMVEC_Human1.30873146
69CDX2_19796622_ChIP-Seq_MESCs_Mouse1.30561971
70NFE2_27457419_Chip-Seq_LIVER_Mouse1.30518389
71CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.30412609
72* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30202903
73TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.29745563
74MYB_26560356_Chip-Seq_TH2_Human1.29173385
75TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.28783251
76SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.26508766
77* CBP_20019798_ChIP-Seq_JUKART_Human1.22115420
78* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.22115420
79CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.21548868
80FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.20931482
81AR_25329375_ChIP-Seq_VCAP_Human1.20622618
82GATA1_22025678_ChIP-Seq_K562_Human1.20407301
83NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.20384329
84MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.20151732
85NANOG_18555785_Chip-Seq_ESCs_Mouse1.19274857
86CRX_20693478_ChIP-Seq_RETINA_Mouse1.18337105
87CTBP2_25329375_ChIP-Seq_LNCAP_Human1.18255799
88ETV2_25802403_ChIP-Seq_MESCs_Mouse1.18122402
89PRDM14_20953172_ChIP-Seq_ESCs_Human1.17557026
90FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.17272727
91PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.17040050
92SMAD4_21741376_ChIP-Seq_EPCs_Human1.16024322
93GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.15662130
94GATA3_21878914_ChIP-Seq_MCF-7_Human1.15061458
95FOXA1_21572438_ChIP-Seq_LNCaP_Human1.14259103
96ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.14036350
97STAT1_20625510_ChIP-Seq_HELA_Human1.12706996
98TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.12222181
99RARG_19884340_ChIP-ChIP_MEFs_Mouse1.11820862
100LXR_22158963_ChIP-Seq_LIVER_Mouse1.11498456
101EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.11187863
102SOX2_20726797_ChIP-Seq_SW620_Human1.10986255
103SUZ12_18555785_Chip-Seq_ESCs_Mouse1.10710016
104TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.10315650
105STAT3_18555785_Chip-Seq_ESCs_Mouse1.10014175
106* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.09899293
107FOXA1_27270436_Chip-Seq_PROSTATE_Human1.09561118
108FOXA1_25329375_ChIP-Seq_VCAP_Human1.09561118
109GATA3_26560356_Chip-Seq_TH2_Human1.09488850
110* PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.09392904
111NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09225329
112TCF4_22108803_ChIP-Seq_LS180_Human1.08481171
113* SMAD3_21741376_ChIP-Seq_EPCs_Human1.08358580
114LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07480911
115PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.04485287
116TFEB_21752829_ChIP-Seq_HELA_Human1.03697143
117P53_22387025_ChIP-Seq_ESCs_Mouse1.03496880
118GATA3_27048872_Chip-Seq_THYMUS_Human1.03048001
119FLI1_21867929_ChIP-Seq_TH2_Mouse1.02285561
120STAT3_23295773_ChIP-Seq_U87_Human1.01755151
121PCGF2_27294783_Chip-Seq_NPCs_Mouse1.01633214
122* RXR_22158963_ChIP-Seq_LIVER_Mouse1.00807926
123EGR1_23403033_ChIP-Seq_LIVER_Mouse1.00309017
124CMYC_18555785_Chip-Seq_ESCs_Mouse1.00240963
125E2F1_18555785_Chip-Seq_ESCs_Mouse1.00080054
126MAF_26560356_Chip-Seq_TH1_Human0.98689484
127AR_21572438_ChIP-Seq_LNCaP_Human0.97981149
128ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.97787789
129OCT4_21477851_ChIP-Seq_ESCs_Mouse0.97772198
130CDX2_22108803_ChIP-Seq_LS180_Human0.97737475
131AR_20517297_ChIP-Seq_VCAP_Human0.97690271
132MYC_19829295_ChIP-Seq_ESCs_Human0.97062299
133TP53_16413492_ChIP-PET_HCT116_Human0.96485631
134GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.96465454
135SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.95385709
136CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.94965215
137TP53_22573176_ChIP-Seq_HFKS_Human0.94789475
138P300_18555785_Chip-Seq_ESCs_Mouse0.94417078
139HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.94397770
140SOX2_18555785_Chip-Seq_ESCs_Mouse0.93865176
141GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.93842707
142EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.93609092
143FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.93592610
144CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.93446722
145SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93226253
146SMAD4_21799915_ChIP-Seq_A2780_Human0.92850484
147GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.92268620
148E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.91358830
149* CJUN_26792858_Chip-Seq_BT549_Human0.90734639
150SCL_19346495_ChIP-Seq_HPC-7_Human0.90576511
151MYB_26560356_Chip-Seq_TH1_Human0.89494000
152GATA2_22383799_ChIP-Seq_G1ME_Mouse0.89379031
153* PPARA_22158963_ChIP-Seq_LIVER_Mouse0.88566100
154LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.87089294
155JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86668254
156GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86248750
157JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.85248391
158SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84602599
159SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.84128777
160CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.81013928
161BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.78333046
162* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.77102870
163PPAR_26484153_Chip-Seq_NCI-H1993_Human0.77043601
164RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.76474724
165SALL4_18804426_ChIP-ChIP_XEN_Mouse0.76075703
166IKZF1_21737484_ChIP-ChIP_HCT116_Human0.75810516
167SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.73906592
168SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.73906592
169SMRT_27268052_Chip-Seq_Bcells_Human0.72156359
170P63_26484246_Chip-Seq_KERATINOCYTES_Human0.72050971
171SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.71219082
172ESR1_21235772_ChIP-Seq_MCF-7_Human0.70522256
173SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.70037703
174VDR_21846776_ChIP-Seq_THP-1_Human0.69455552
175TRIM28_21343339_ChIP-Seq_HEK293_Human0.68636685
176* FOXO3_23340844_ChIP-Seq_DLD1_Human0.67443728

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.38017547
2MP0003436_decreased_susceptibility_to4.04766104
3MP0005058_abnormal_lysosome_morphology3.84069083
4MP0006082_CNS_inflammation3.73240353
5MP0003303_peritoneal_inflammation3.49120431
6MP0002148_abnormal_hypersensitivity_rea3.46111942
7MP0002419_abnormal_innate_immunity3.39990559
8MP0009785_altered_susceptibility_to3.19064932
9MP0003724_increased_susceptibility_to3.11303276
10MP0002139_abnormal_hepatobiliary_system3.07283166
11MP0005000_abnormal_immune_tolerance3.00469000
12MP0002837_dystrophic_cardiac_calcinosis2.90716873
13MP0005025_abnormal_response_to2.77865858
14MP0004510_myositis2.68073434
15MP0003191_abnormal_cellular_cholesterol2.66756875
16MP0005084_abnormal_gallbladder_morpholo2.57499903
17MP0002452_abnormal_antigen_presenting2.46775808
18MP0003172_abnormal_lysosome_physiology2.42725402
19MP0005387_immune_system_phenotype2.30705297
20MP0001790_abnormal_immune_system2.30705297
21MP0002723_abnormal_immune_serum2.18766345
22MP0001533_abnormal_skeleton_physiology2.06755992
23MP0005464_abnormal_platelet_physiology2.02363988
24MP0001819_abnormal_immune_cell1.99784956
25MP0005671_abnormal_response_to1.96878739
26MP0009764_decreased_sensitivity_to1.96618779
27MP0002420_abnormal_adaptive_immunity1.96445031
28MP0005257_abnormal_intraocular_pressure1.96256705
29MP0003075_altered_response_to1.88555663
30MP0002405_respiratory_system_inflammati1.88372082
31MP0000343_altered_response_to1.88329671
32MP0001800_abnormal_humoral_immune1.87766024
33MP0001853_heart_inflammation1.87334459
34MP0003690_abnormal_glial_cell1.85249061
35MP0009840_abnormal_foam_cell1.85212666
36MP0003646_muscle_fatigue1.84959950
37MP0005166_decreased_susceptibility_to1.82821352
38MP0000685_abnormal_immune_system1.82266281
39MP0001845_abnormal_inflammatory_respons1.78508422
40MP0003448_altered_tumor_morphology1.76936810
41* MP0002998_abnormal_bone_remodeling1.73384585
42MP0010386_abnormal_urinary_bladder1.73148656
43MP0005365_abnormal_bile_salt1.68928608
44MP0004782_abnormal_surfactant_physiolog1.66676736
45MP0008469_abnormal_protein_level1.60531453
46MP0005310_abnormal_salivary_gland1.60245539
47MP0004947_skin_inflammation1.55544579
48MP0000604_amyloidosis1.55231908
49MP0003186_abnormal_redox_activity1.53194271
50MP0000569_abnormal_digit_pigmentation1.50805427
51MP0003806_abnormal_nucleotide_metabolis1.40074832
52MP0005379_endocrine/exocrine_gland_phen1.38313852
53MP0004043_abnormal_pH_regulation1.37164097
54MP0002254_reproductive_system_inflammat1.35502432
55MP0005167_abnormal_blood-brain_barrier1.32908443
56MP0005174_abnormal_tail_pigmentation1.31369951
57MP0000858_altered_metastatic_potential1.30960434
58MP0004019_abnormal_vitamin_homeostasis1.30367316
59MP0006054_spinal_hemorrhage1.27763007
60MP0008875_abnormal_xenobiotic_pharmacok1.25922632
61MP0010155_abnormal_intestine_physiology1.25234788
62* MP0000716_abnormal_immune_system1.24707698
63MP0003950_abnormal_plasma_membrane1.24394678
64MP0001851_eye_inflammation1.22000163
65MP0003329_amyloid_beta_deposits1.18936278
66MP0002653_abnormal_ependyma_morphology1.18509984
67MP0003136_yellow_coat_color1.18067653
68MP0005164_abnormal_response_to1.17961054
69MP0001501_abnormal_sleep_pattern1.17868456
70MP0002090_abnormal_vision1.16205948
71MP0005646_abnormal_pituitary_gland1.14890371
72MP0009333_abnormal_splenocyte_physiolog1.14450511
73MP0005551_abnormal_eye_electrophysiolog1.14267390
74MP0003828_pulmonary_edema1.11608470
75MP0005647_abnormal_sex_gland1.10072724
76MP0008961_abnormal_basal_metabolism1.08729828
77MP0009046_muscle_twitch1.06822130
78MP0006072_abnormal_retinal_apoptosis1.06609853
79MP0005253_abnormal_eye_physiology1.05560734
80MP0002006_tumorigenesis1.04204435
81MP0005377_hearing/vestibular/ear_phenot1.03541311
82MP0003878_abnormal_ear_physiology1.03541311
83MP0002138_abnormal_hepatobiliary_system1.01133666
84MP0008438_abnormal_cutaneous_collagen1.00653421
85MP0005390_skeleton_phenotype1.00300585
86MP0002693_abnormal_pancreas_physiology0.98294457
87MP0002398_abnormal_bone_marrow0.98002845
88MP0001958_emphysema0.97962653
89MP0005410_abnormal_fertilization0.97625233
90MP0000920_abnormal_myelination0.97076014
91MP0004130_abnormal_muscle_cell0.96464572
92MP0004742_abnormal_vestibular_system0.96429491
93* MP0002429_abnormal_blood_cell0.96195714
94MP0004185_abnormal_adipocyte_glucose0.94496507
95MP0002933_joint_inflammation0.94441180
96MP0003195_calcinosis0.93267697
97MP0002229_neurodegeneration0.92484492
98MP0000689_abnormal_spleen_morphology0.91810597
99MP0008260_abnormal_autophagy0.90588336
100MP0002102_abnormal_ear_morphology0.89106866
101MP0004883_abnormal_blood_vessel0.88689321
102MP0009763_increased_sensitivity_to0.88656121
103MP0002876_abnormal_thyroid_physiology0.87506399
104MP0003566_abnormal_cell_adhesion0.86866927
105MP0003633_abnormal_nervous_system0.86158913
106MP0001764_abnormal_homeostasis0.84632466
107MP0000371_diluted_coat_color0.83084620
108MP0003705_abnormal_hypodermis_morpholog0.82990913
109MP0002722_abnormal_immune_system0.82258215
110MP0005448_abnormal_energy_balance0.82215938
111MP0005451_abnormal_body_composition0.81015140
112MP0000372_irregular_coat_pigmentation0.80764115
113MP0003279_aneurysm0.79773042
114MP0009278_abnormal_bone_marrow0.79251653
115MP0003656_abnormal_erythrocyte_physiolo0.78812610
116MP0000383_abnormal_hair_follicle0.78419236
117MP0000249_abnormal_blood_vessel0.78074430
118* MP0003795_abnormal_bone_structure0.78016332
119MP0002136_abnormal_kidney_physiology0.77944253
120MP0003183_abnormal_peptide_metabolism0.75671781
121MP0003300_gastrointestinal_ulcer0.75406347
122MP0001545_abnormal_hematopoietic_system0.73341111
123MP0005397_hematopoietic_system_phenotyp0.73341111
124MP0003453_abnormal_keratinocyte_physiol0.69048889
125MP0001324_abnormal_eye_pigmentation0.68384865
126MP0005636_abnormal_mineral_homeostasis0.67996955
127MP0002277_abnormal_respiratory_mucosa0.67994234
128MP0001663_abnormal_digestive_system0.67751495
129MP0001485_abnormal_pinna_reflex0.66938936
130MP0010329_abnormal_lipoprotein_level0.66339213
131MP0001986_abnormal_taste_sensitivity0.65860761
132MP0002064_seizures0.65070753
133MP0002295_abnormal_pulmonary_circulatio0.64029929
134MP0000465_gastrointestinal_hemorrhage0.61773494
135MP0005076_abnormal_cell_differentiation0.60843483
136MP0010307_abnormal_tumor_latency0.60758434
137MP0001542_abnormal_bone_strength0.60602300
138MP0000609_abnormal_liver_physiology0.58468339
139MP0005319_abnormal_enzyme/_coenzyme0.58008834
140MP0003011_delayed_dark_adaptation0.54910119

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)7.93992606
2Recurrent gram-negative bacterial infections (HP:0005420)7.79257470
3Recurrent abscess formation (HP:0002722)7.66792117
4Recurrent bacterial skin infections (HP:0005406)6.84293263
5Increased cerebral lipofuscin (HP:0011813)6.12338267
6Abnormality of macrophages (HP:0004311)5.95571512
7Vacuolated lymphocytes (HP:0001922)5.71551620
8Increased neuronal autofluorescent lipopigment (HP:0002074)5.29870935
9Axonal loss (HP:0003447)4.84497820
10Mediastinal lymphadenopathy (HP:0100721)4.59815136
11Gingivitis (HP:0000230)4.56797569
12Recurrent skin infections (HP:0001581)4.32744721
13Obstructive lung disease (HP:0006536)4.18162825
14Chronic obstructive pulmonary disease (HP:0006510)4.18162825
15Abnormality of liposaccharide metabolism (HP:0010968)4.11565284
16Abnormality of glycosphingolipid metabolism (HP:0004343)4.11565284
17Abnormality of glycolipid metabolism (HP:0010969)4.11565284
18Autoimmune thrombocytopenia (HP:0001973)4.03540687
19Disinhibition (HP:0000734)3.95178950
20Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.90710423
21Dysostosis multiplex (HP:0000943)3.76538672
22Recurrent fungal infections (HP:0002841)3.74850346
23Mutism (HP:0002300)3.69935674
24Stomatitis (HP:0010280)3.54086774
25Interstitial pulmonary disease (HP:0006530)3.39309426
26Orchitis (HP:0100796)3.27301178
27Polyuria (HP:0000103)3.25910762
28Myositis (HP:0100614)3.25052573
29Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.24665709
30Mucopolysacchariduria (HP:0008155)3.22501970
31Urinary glycosaminoglycan excretion (HP:0003541)3.22501970
32Systemic lupus erythematosus (HP:0002725)3.16311423
33Chronic mucocutaneous candidiasis (HP:0002728)3.06876174
34Recurrent cutaneous fungal infections (HP:0011370)3.06876174
35Myocardial infarction (HP:0001658)3.05966690
36Agnosia (HP:0010524)3.03230733
37Abnormality of mucopolysaccharide metabolism (HP:0011020)3.01627595
38Abnormality of polysaccharide metabolism (HP:0011012)3.01627595
39Abnormality of glycosaminoglycan metabolism (HP:0004371)3.01627595
40Cellulitis (HP:0100658)2.96171461
41Retrobulbar optic neuritis (HP:0100654)2.96103112
42Optic neuritis (HP:0100653)2.96103112
43Loss of speech (HP:0002371)2.95412226
44Abnormal drinking behavior (HP:0030082)2.94092381
45Polydipsia (HP:0001959)2.94092381
46Basal ganglia calcification (HP:0002135)2.92071461
47Urticaria (HP:0001025)2.91765749
48Joint hemorrhage (HP:0005261)2.88787858
49Metaphyseal irregularity (HP:0003025)2.79954079
50Hepatosplenomegaly (HP:0001433)2.79793444
51Periodontitis (HP:0000704)2.69857629
52Abnormality of the vasculature of the conjunctiva (HP:0008054)2.68973782
53Abnormal urine output (HP:0012590)2.67771818
54Elevated erythrocyte sedimentation rate (HP:0003565)2.67034496
55Upper motor neuron abnormality (HP:0002127)2.66525877
56Osteomyelitis (HP:0002754)2.66378728
57Abnormality of midbrain morphology (HP:0002418)2.64507735
58Molar tooth sign on MRI (HP:0002419)2.64507735
59Nausea (HP:0002018)2.64056450
60Abolished electroretinogram (ERG) (HP:0000550)2.56596294
61Recurrent pneumonia (HP:0006532)2.55737286
62Prostate neoplasm (HP:0100787)2.53262788
63Vasculitis (HP:0002633)2.51233905
64Abnormality of calcium-phosphate metabolism (HP:0100530)2.49858520
65Hyperventilation (HP:0002883)2.49166645
66Bone pain (HP:0002653)2.36972161
67Conjunctival telangiectasia (HP:0000524)2.36594450
68Purpura (HP:0000979)2.35789576
69Peripheral demyelination (HP:0011096)2.33315518
70Congenital stationary night blindness (HP:0007642)2.32482351
71Pancreatic cysts (HP:0001737)2.30500488
72Abnormality of renal excretion (HP:0011036)2.30285458
73Abnormality of the vertebral endplates (HP:0005106)2.26076992
74Pustule (HP:0200039)2.25480157
75Recurrent viral infections (HP:0004429)2.23903977
76Amelogenesis imperfecta (HP:0000705)2.23786556
77Tubulointerstitial fibrosis (HP:0005576)2.22885702
78Hemoptysis (HP:0002105)2.20774005
79Meningitis (HP:0001287)2.19991738
80Cheilitis (HP:0100825)2.17642745
81Bone cyst (HP:0012062)2.16144554
82Pathologic fracture (HP:0002756)2.15162636
83Abnormality of dental color (HP:0011073)2.13317033
84Petechiae (HP:0000967)2.10960474
85Pulmonary infiltrates (HP:0002113)2.10553787
86True hermaphroditism (HP:0010459)2.10306896
87Thick nail (HP:0001805)2.07116562
88Nephronophthisis (HP:0000090)2.06306504
89Spontaneous hematomas (HP:0007420)2.05777734
90Recurrent lower respiratory tract infections (HP:0002783)2.05563618
91Osteolytic defects of the hand bones (HP:0009699)2.04081717
92Osteolytic defects of the phalanges of the hand (HP:0009771)2.04081717
93Irregular vertebral endplates (HP:0003301)2.03089330
94Gingival bleeding (HP:0000225)2.03059170
95Pancreatic fibrosis (HP:0100732)2.02794342
96Tetraparesis (HP:0002273)2.01187093
97Neurofibrillary tangles (HP:0002185)1.98633003
98Glomerulonephritis (HP:0000099)1.97008290
99Mesangial abnormality (HP:0001966)1.96918262
100Retinal atrophy (HP:0001105)1.96243953
101Poor head control (HP:0002421)1.95788431
102Inappropriate behavior (HP:0000719)1.95601861
103Abnormality of transition element cation homeostasis (HP:0011030)1.94154293
104Mucosal telangiectasiae (HP:0100579)1.93434689
105Agitation (HP:0000713)1.93277509
106Hypomagnesemia (HP:0002917)1.92149704
107Segmental peripheral demyelination/remyelination (HP:0003481)1.90677045
108Sepsis (HP:0100806)1.90336245
109Diminished motivation (HP:0000745)1.90241190
110Hypokalemic alkalosis (HP:0001949)1.90107226
111Tetany (HP:0001281)1.89624283
112Leukocytosis (HP:0001974)1.89571626
113Premature loss of primary teeth (HP:0006323)1.89067000
114Polyneuropathy (HP:0001271)1.88779576
115Nuclear cataract (HP:0100018)1.88205365
116Progressive visual loss (HP:0000529)1.88046814
117J-shaped sella turcica (HP:0002680)1.87147295
118Abnormality of the renal medulla (HP:0100957)1.86119991
119Apathy (HP:0000741)1.85817082
120Increased IgM level (HP:0003496)1.85016018
121Hypercholesterolemia (HP:0003124)1.83914813
122Arterial thrombosis (HP:0004420)1.83524245
123Abnormality of renal resorption (HP:0011038)1.83035127
124Keratoconjunctivitis (HP:0001096)1.82306379
125Increased CSF protein (HP:0002922)1.81148578
126Adactyly (HP:0009776)1.81045363
127Decreased circulating renin level (HP:0003351)1.80630420
128Metabolic alkalosis (HP:0200114)1.80068267
129Decreased electroretinogram (ERG) amplitude (HP:0000654)1.79962355
130Increased circulating renin level (HP:0000848)1.79334671
131Albinism (HP:0001022)1.79012966
132Epidermoid cyst (HP:0200040)1.77954975
133Abnormality of the periventricular white matter (HP:0002518)1.77666005
134Tubular atrophy (HP:0000092)1.77643058
135Spondylolisthesis (HP:0003302)1.77469958
136Congenital sensorineural hearing impairment (HP:0008527)1.77003839
137Menorrhagia (HP:0000132)1.76184389
138Attenuation of retinal blood vessels (HP:0007843)1.75467326
139Abnormality of the lumbar spine (HP:0100712)1.74931225
140Abnormal rod and cone electroretinograms (HP:0008323)1.74044827
141Esophageal varix (HP:0002040)1.73627093
142Vertebral compression fractures (HP:0002953)1.73256797
143Abnormality of the renal cortex (HP:0011035)1.72143438
144Abnormality of T cell number (HP:0011839)1.71823084
145Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.70770153
146Progressive neurologic deterioration (HP:0002344)1.70617734
147Generalized aminoaciduria (HP:0002909)1.70180219
148Gastrointestinal stroma tumor (HP:0100723)1.69870945
149Asymmetric septal hypertrophy (HP:0001670)1.69556186
150Parakeratosis (HP:0001036)1.68703363
151Hematochezia (HP:0002573)1.68378900
152Abnormality of the pericardium (HP:0001697)1.68013811
153Hypophosphatemic rickets (HP:0004912)1.67772652
154Clumsiness (HP:0002312)1.67215462
155Increased serum ferritin (HP:0003281)1.66933402
156Abnormality of the prostate (HP:0008775)1.66152305
157Inability to walk (HP:0002540)1.64821641
158Tubulointerstitial abnormality (HP:0001969)1.62538517
159Polyphagia (HP:0002591)1.62353257
160T lymphocytopenia (HP:0005403)1.61985649
161Abnormality of renin-angiotensin system (HP:0000847)1.60539436

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PBK5.51416150
2RIPK44.75955247
3BLK4.02363379
4ACVR1B3.74965449
5FRK3.73510932
6MAP3K143.31072094
7TBK12.94951586
8IRAK32.87338317
9IRAK42.67895301
10MAP4K12.67081267
11WNK32.60352318
12NTRK22.39500683
13ERN12.29471165
14ABL22.23403839
15TYK22.10831077
16WNK42.09894615
17NEK92.06520359
18MST1R2.05661569
19NME22.00154357
20MAP4K21.98653963
21IKBKB1.89440109
22KIT1.89033850
23OXSR11.85730393
24TXK1.75796574
25PIM21.70722083
26GRK11.60713712
27PINK11.60533855
28JAK11.58687397
29TGFBR21.56771787
30IKBKE1.48413568
31JAK31.42361209
32SYK1.37687714
33MST41.33637211
34BMX1.33480327
35MARK31.32152591
36DDR21.28946110
37STK391.28188545
38HCK1.27462975
39TLK11.27165302
40NUAK11.26126458
41TRPM71.25622108
42CSK1.25226086
43ZAP701.23695171
44ZAK1.21503515
45LYN1.19409328
46ERBB31.15732957
47MAP2K61.15484906
48TAOK31.12592855
49MAP3K101.11180963
50TNIK1.09858556
51FGR1.03429771
52GRK71.01818035
53CHUK1.00601666
54MAP3K131.00475031
55INSRR1.00255967
56JAK20.99746836
57STK40.95454633
58BTK0.95042096
59ARAF0.92198134
60CSF1R0.89515133
61LCK0.89073014
62BMPR20.88808475
63RPS6KA40.85814067
64EPHB10.85447599
65MAP3K120.85012023
66PIM10.84503718
67CDC42BPA0.84229749
68RIPK10.83596369
69STK100.83559660
70TEC0.83176973
71PDK20.81607202
72PRKCD0.81416955
73CLK10.81083080
74MATK0.79931377
75ABL10.78343140
76MAP3K110.77871659
77MAPK130.72536833
78YES10.72279370
79TGFBR10.72108746
80LRRK20.71207649
81CSNK1G20.71191880
82TRIB30.70532640
83EGFR0.70375512
84PRKCG0.69764392
85TRIM280.67144190
86SCYL20.64716543
87CAMK1D0.64640125
88ADRBK10.64637278
89MAP2K30.63490482
90CSNK1G30.63224078
91LIMK10.62505420
92PKN10.59994983
93PRKCH0.59795502
94FGFR30.58947668
95IRAK10.58848356
96CASK0.58146568
97CSNK1G10.57896705
98IRAK20.53826411
99PRKCQ0.53603650
100MAP3K40.53345560
101TTN0.53181633
102ERBB40.52911263
103FES0.51935694
104MOS0.51651227
105PDPK10.50927738
106ITK0.50303336
107BCKDK0.50085558
108BMPR1B0.48728867
109PTK60.48264864
110PRKCE0.48214132
111EPHA30.47398712
112KSR20.47301970
113DAPK20.45433389
114PDK10.44741902
115MAP3K10.44074533
116MAP3K30.42792271
117MAPK150.42525632
118CAMK1G0.42058858
119CSNK1A1L0.41859611
120STK30.41289275
121CAMKK20.40786102
122MET0.40603906
123CSNK1A10.40434686
124SIK30.39977207
125FYN0.39246434
126DAPK30.39001215
127ADRBK20.38169344
128PDGFRB0.37519560
129STK160.36559945
130PRKCA0.36362068
131MAP3K50.36337791
132PLK20.36227767
133CAMKK10.35983425
134MUSK0.35681705
135CDK60.35235175
136EIF2AK20.32970112
137RPS6KA60.32685239
138MAP3K20.32576067
139PRKACA0.31311761
140PRKAA20.31094841
141TAOK20.30878260
142IGF1R0.29920519
143EIF2AK30.29756348
144PAK40.28453060
145CAMK2A0.27915586
146TAOK10.27545141
147CAMK10.26830984

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051403.39323476
2* Lysosome_Homo sapiens_hsa041423.37886222
3Staphylococcus aureus infection_Homo sapiens_hsa051503.08118214
4* Rheumatoid arthritis_Homo sapiens_hsa053233.02367193
5* Phagosome_Homo sapiens_hsa041452.80583073
6Graft-versus-host disease_Homo sapiens_hsa053322.80232018
7* Tuberculosis_Homo sapiens_hsa051522.69827707
8Osteoclast differentiation_Homo sapiens_hsa043802.61435716
9Toll-like receptor signaling pathway_Homo sapiens_hsa046202.59629642
10Legionellosis_Homo sapiens_hsa051342.53639983
11Glycosaminoglycan degradation_Homo sapiens_hsa005312.41353856
12Malaria_Homo sapiens_hsa051442.31901849
13Pertussis_Homo sapiens_hsa051332.23203887
14NF-kappa B signaling pathway_Homo sapiens_hsa040642.18313416
15NOD-like receptor signaling pathway_Homo sapiens_hsa046211.93031602
16Sulfur metabolism_Homo sapiens_hsa009201.90838729
17Other glycan degradation_Homo sapiens_hsa005111.90744018
18* Collecting duct acid secretion_Homo sapiens_hsa049661.88850719
19Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.88681699
20Salmonella infection_Homo sapiens_hsa051321.85385795
21Allograft rejection_Homo sapiens_hsa053301.73456111
22Primary bile acid biosynthesis_Homo sapiens_hsa001201.72905922
23Asthma_Homo sapiens_hsa053101.66690868
24alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.62954876
25Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.61770650
26Ether lipid metabolism_Homo sapiens_hsa005651.56352092
27Complement and coagulation cascades_Homo sapiens_hsa046101.55804116
28Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.53590058
29Hematopoietic cell lineage_Homo sapiens_hsa046401.50902472
30RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.48708049
31Measles_Homo sapiens_hsa051621.46429376
32Linoleic acid metabolism_Homo sapiens_hsa005911.44298683
33Type I diabetes mellitus_Homo sapiens_hsa049401.44231201
34TNF signaling pathway_Homo sapiens_hsa046681.40984335
35* Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.40686902
36Apoptosis_Homo sapiens_hsa042101.36820984
37* Oxidative phosphorylation_Homo sapiens_hsa001901.34864109
38Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.27940327
39Toxoplasmosis_Homo sapiens_hsa051451.27779056
40B cell receptor signaling pathway_Homo sapiens_hsa046621.27478352
41Influenza A_Homo sapiens_hsa051641.26752754
42Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.26016796
43Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.25224936
44Intestinal immune network for IgA production_Homo sapiens_hsa046721.24128103
45Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.23108337
46Shigellosis_Homo sapiens_hsa051311.22980353
47Tryptophan metabolism_Homo sapiens_hsa003801.22334264
48Olfactory transduction_Homo sapiens_hsa047401.21184055
49Pentose and glucuronate interconversions_Homo sapiens_hsa000401.20167312
50Antigen processing and presentation_Homo sapiens_hsa046121.18805123
51Phototransduction_Homo sapiens_hsa047441.18659018
52Chemokine signaling pathway_Homo sapiens_hsa040621.13126751
53Steroid biosynthesis_Homo sapiens_hsa001001.11910960
54Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.08185882
55African trypanosomiasis_Homo sapiens_hsa051431.03032002
56Amoebiasis_Homo sapiens_hsa051461.02399233
57Ovarian steroidogenesis_Homo sapiens_hsa049131.01862090
58Nitrogen metabolism_Homo sapiens_hsa009101.01760762
59Leukocyte transendothelial migration_Homo sapiens_hsa046700.94679304
60Jak-STAT signaling pathway_Homo sapiens_hsa046300.93650567
61AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.91968703
62Selenocompound metabolism_Homo sapiens_hsa004500.91660768
63* Vibrio cholerae infection_Homo sapiens_hsa051100.86769613
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.85512358
65Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.84843655
66Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.82898917
67Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.82781833
68Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.82002786
69Mineral absorption_Homo sapiens_hsa049780.80789284
70Arachidonic acid metabolism_Homo sapiens_hsa005900.80020048
71Caffeine metabolism_Homo sapiens_hsa002320.78933442
72Viral myocarditis_Homo sapiens_hsa054160.78721189
73Autoimmune thyroid disease_Homo sapiens_hsa053200.77326112
74Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.77158474
75Hepatitis B_Homo sapiens_hsa051610.75613270
76SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73859271
77Sphingolipid metabolism_Homo sapiens_hsa006000.72559850
78Herpes simplex infection_Homo sapiens_hsa051680.70937559
79Maturity onset diabetes of the young_Homo sapiens_hsa049500.69839426
80Renin-angiotensin system_Homo sapiens_hsa046140.68176727
81Hepatitis C_Homo sapiens_hsa051600.67087777
82Histidine metabolism_Homo sapiens_hsa003400.64874073
83Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63669630
84PPAR signaling pathway_Homo sapiens_hsa033200.62549512
85Platelet activation_Homo sapiens_hsa046110.61401986
86Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.60476418
87Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.58483116
88Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58191281
89ABC transporters_Homo sapiens_hsa020100.57166077
90Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56865887
91Parkinsons disease_Homo sapiens_hsa050120.56749526
92Acute myeloid leukemia_Homo sapiens_hsa052210.51585082
93Taste transduction_Homo sapiens_hsa047420.51570731
94T cell receptor signaling pathway_Homo sapiens_hsa046600.50967197
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.50293665
96Morphine addiction_Homo sapiens_hsa050320.48799749
97Adipocytokine signaling pathway_Homo sapiens_hsa049200.47833454
98Prion diseases_Homo sapiens_hsa050200.46636270
99Butanoate metabolism_Homo sapiens_hsa006500.46317841
100Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.44140574
101Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.43534410
102Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.41684678
103Neurotrophin signaling pathway_Homo sapiens_hsa047220.40361885
104Chronic myeloid leukemia_Homo sapiens_hsa052200.40192946
105Pancreatic cancer_Homo sapiens_hsa052120.39802316
106Endocytosis_Homo sapiens_hsa041440.38058315
107Protein export_Homo sapiens_hsa030600.37133287
108Primary immunodeficiency_Homo sapiens_hsa053400.35746218
109Steroid hormone biosynthesis_Homo sapiens_hsa001400.35729906
110Salivary secretion_Homo sapiens_hsa049700.35270465
111Regulation of actin cytoskeleton_Homo sapiens_hsa048100.33610313
112Proteoglycans in cancer_Homo sapiens_hsa052050.32459120
113* Synaptic vesicle cycle_Homo sapiens_hsa047210.32043719
114HIF-1 signaling pathway_Homo sapiens_hsa040660.31691601
115Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.30890077
116Chemical carcinogenesis_Homo sapiens_hsa052040.30151413
117Glutathione metabolism_Homo sapiens_hsa004800.29887603
118Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.28146893
119Prolactin signaling pathway_Homo sapiens_hsa049170.27705487
120Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.26484245
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.26397132
122Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.26161632
123Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.25916773
124Insulin secretion_Homo sapiens_hsa049110.25495081
125Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.24992177
126Serotonergic synapse_Homo sapiens_hsa047260.24602236
127Alzheimers disease_Homo sapiens_hsa050100.24272524
128GABAergic synapse_Homo sapiens_hsa047270.22688995
129Type II diabetes mellitus_Homo sapiens_hsa049300.18896582
130Starch and sucrose metabolism_Homo sapiens_hsa005000.18522013
131Dorso-ventral axis formation_Homo sapiens_hsa043200.18502011
132Insulin resistance_Homo sapiens_hsa049310.18350267
133Regulation of autophagy_Homo sapiens_hsa041400.17459017
134Peroxisome_Homo sapiens_hsa041460.15306137
135Epstein-Barr virus infection_Homo sapiens_hsa051690.14838854
136Carbohydrate digestion and absorption_Homo sapiens_hsa049730.14732998
137beta-Alanine metabolism_Homo sapiens_hsa004100.12208802

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