

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 6.67365583 |
| 2 | regulation of ruffle assembly (GO:1900027) | 6.41956138 |
| 3 | regulation of hydrogen peroxide metabolic process (GO:0010310) | 6.37032437 |
| 4 | dermatan sulfate metabolic process (GO:0030205) | 6.23336959 |
| 5 | positive regulation of protein kinase C signaling (GO:0090037) | 5.84078673 |
| 6 | chondroitin sulfate catabolic process (GO:0030207) | 5.57409337 |
| 7 | semaphorin-plexin signaling pathway (GO:0071526) | 5.55128335 |
| 8 | response to manganese ion (GO:0010042) | 5.28372368 |
| 9 | face development (GO:0060324) | 5.15572371 |
| 10 | negative regulation of cell size (GO:0045792) | 5.15096323 |
| 11 | quaternary ammonium group transport (GO:0015697) | 5.03683081 |
| 12 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 4.94284979 |
| 13 | negative regulation of osteoblast proliferation (GO:0033689) | 4.88077475 |
| 14 | regulation of ARF GTPase activity (GO:0032312) | 4.76190145 |
| 15 | histone H3-K9 demethylation (GO:0033169) | 4.74244231 |
| 16 | response to magnesium ion (GO:0032026) | 4.70599046 |
| 17 | mannose metabolic process (GO:0006013) | 4.38237469 |
| 18 | ear development (GO:0043583) | 4.24433449 |
| 19 | endothelial cell chemotaxis (GO:0035767) | 4.19462842 |
| 20 | positive regulation of histone deacetylation (GO:0031065) | 4.17972430 |
| 21 | regulation of histone H3-K27 methylation (GO:0061085) | 4.14300693 |
| 22 | diacylglycerol metabolic process (GO:0046339) | 4.10733403 |
| 23 | vascular endothelial growth factor signaling pathway (GO:0038084) | 3.88791872 |
| 24 | facial nerve structural organization (GO:0021612) | 3.85040441 |
| 25 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 3.84722706 |
| 26 | negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037) | 3.79916426 |
| 27 | atrioventricular valve morphogenesis (GO:0003181) | 3.74557833 |
| 28 | regulation of protein polyubiquitination (GO:1902914) | 3.71041769 |
| 29 | regulation of respiratory burst (GO:0060263) | 3.65990072 |
| 30 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.62569255 |
| 31 | Rho protein signal transduction (GO:0007266) | 3.53880134 |
| 32 | regulation of clathrin-mediated endocytosis (GO:2000369) | 3.52696687 |
| 33 | white fat cell differentiation (GO:0050872) | 3.50029904 |
| 34 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.46433078 |
| 35 | melanocyte differentiation (GO:0030318) | 3.36566051 |
| 36 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 3.34341267 |
| 37 | actin filament bundle assembly (GO:0051017) | 3.30357412 |
| 38 | actin filament bundle organization (GO:0061572) | 3.30357412 |
| 39 | definitive hemopoiesis (GO:0060216) | 3.22740762 |
| 40 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 3.21135077 |
| 41 | 2-oxoglutarate metabolic process (GO:0006103) | 3.18970461 |
| 42 | phosphatidylinositol 3-kinase signaling (GO:0014065) | 3.17593101 |
| 43 | lytic vacuole organization (GO:0080171) | 3.16876032 |
| 44 | lysosome organization (GO:0007040) | 3.16876032 |
| 45 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 3.16874653 |
| 46 | histone H4 deacetylation (GO:0070933) | 3.16283595 |
| 47 | regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640) | 3.14922739 |
| 48 | positive regulation of protein deacetylation (GO:0090312) | 3.09952647 |
| 49 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.08598662 |
| 50 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 3.08316632 |
| 51 | interferon-gamma secretion (GO:0072643) | 3.08082893 |
| 52 | regulation of triglyceride catabolic process (GO:0010896) | 3.07930216 |
| 53 | histone H3 deacetylation (GO:0070932) | 3.06549397 |
| 54 | pigment cell differentiation (GO:0050931) | 3.05691325 |
| 55 | cranial nerve morphogenesis (GO:0021602) | 3.04541814 |
| 56 | regulation of protein kinase C signaling (GO:0090036) | 3.04095112 |
| 57 | sulfur compound catabolic process (GO:0044273) | 3.00508593 |
| 58 | dendritic cell chemotaxis (GO:0002407) | 2.99802573 |
| 59 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.99541033 |
| 60 | regulation of apoptotic cell clearance (GO:2000425) | 2.97752237 |
| 61 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.93705896 |
| 62 | regulation of histone deacetylation (GO:0031063) | 2.89175063 |
| 63 | regulation of Rho protein signal transduction (GO:0035023) | 2.88987401 |
| 64 | positive regulation of macroautophagy (GO:0016239) | 2.87909156 |
| 65 | negative regulation of transcription by competitive promoter binding (GO:0010944) | 2.87045550 |
| 66 | endocrine hormone secretion (GO:0060986) | 2.83442734 |
| 67 | phospholipid scrambling (GO:0017121) | 2.82251543 |
| 68 | melanosome localization (GO:0032400) | 2.79781296 |
| 69 | activation of JUN kinase activity (GO:0007257) | 2.77953111 |
| 70 | regulation of cell migration involved in sprouting angiogenesis (GO:0090049) | 2.76667031 |
| 71 | phosphatidylglycerol biosynthetic process (GO:0006655) | 2.75367875 |
| 72 | regulation of sequestering of triglyceride (GO:0010889) | 2.71386002 |
| 73 | pigment granule localization (GO:0051875) | 2.69269613 |
| 74 | cardiac right ventricle morphogenesis (GO:0003215) | 2.68790747 |
| 75 | urinary tract smooth muscle contraction (GO:0014848) | 2.68349600 |
| 76 | regulation of T cell cytokine production (GO:0002724) | 2.66073450 |
| 77 | glycerophospholipid catabolic process (GO:0046475) | 2.65013002 |
| 78 | histone H3-K4 trimethylation (GO:0080182) | 2.64748321 |
| 79 | cranial nerve structural organization (GO:0021604) | 2.64627136 |
| 80 | lymph vessel development (GO:0001945) | 2.64555185 |
| 81 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.64049722 |
| 82 | negative regulation of protein tyrosine kinase activity (GO:0061099) | 2.63588524 |
| 83 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 2.59218902 |
| 84 | Rap protein signal transduction (GO:0032486) | 2.58828694 |
| 85 | COPI coating of Golgi vesicle (GO:0048205) | 2.57896745 |
| 86 | Golgi transport vesicle coating (GO:0048200) | 2.57896745 |
| 87 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 2.57131411 |
| 88 | negative regulation of interleukin-2 production (GO:0032703) | 2.57026451 |
| 89 | regulation of synapse maturation (GO:0090128) | 2.55393204 |
| 90 | positive regulation of bone remodeling (GO:0046852) | 2.54880313 |
| 91 | positive regulation of bone resorption (GO:0045780) | 2.54880313 |
| 92 | cell migration in hindbrain (GO:0021535) | 2.54388161 |
| 93 | glomerular filtration (GO:0003094) | 2.54261937 |
| 94 | glycosaminoglycan catabolic process (GO:0006027) | 2.53362565 |
| 95 | activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) | 2.52507101 |
| 96 | cAMP biosynthetic process (GO:0006171) | 2.52395386 |
| 97 | regulation of interleukin-13 production (GO:0032656) | 2.50650367 |
| 98 | retrograde transport, endosome to Golgi (GO:0042147) | 2.49261491 |
| 99 | regulation of establishment or maintenance of cell polarity (GO:0032878) | 2.48856259 |
| 100 | protein heterotrimerization (GO:0070208) | 2.48633622 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 6.06766897 |
| 2 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 4.62549206 |
| 3 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 3.73714478 |
| 4 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 3.69692277 |
| 5 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 3.57429977 |
| 6 | DROSHA_22980978_ChIP-Seq_HELA_Human | 3.25211595 |
| 7 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 2.61541798 |
| 8 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 2.55783623 |
| 9 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.55525863 |
| 10 | RACK7_27058665_Chip-Seq_MCF-7_Human | 2.47253998 |
| 11 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.44899397 |
| 12 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.42516610 |
| 13 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 2.40604310 |
| 14 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.35480016 |
| 15 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.31863130 |
| 16 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.30486056 |
| 17 | P68_20966046_ChIP-Seq_HELA_Human | 2.22057921 |
| 18 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.17260543 |
| 19 | CTCF_27219007_Chip-Seq_Bcells_Human | 2.15466985 |
| 20 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.12413410 |
| 21 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.09817795 |
| 22 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.05558052 |
| 23 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.92763733 |
| 24 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.88377030 |
| 25 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.86014032 |
| 26 | KDM2B_26808549_Chip-Seq_K562_Human | 1.84927161 |
| 27 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.80005186 |
| 28 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.79666312 |
| 29 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.77890737 |
| 30 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.72314344 |
| 31 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.64672610 |
| 32 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.60220989 |
| 33 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.59459221 |
| 34 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.59323769 |
| 35 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.54307102 |
| 36 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.52127325 |
| 37 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.50516993 |
| 38 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.49693791 |
| 39 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.48270409 |
| 40 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.42911757 |
| 41 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.39713886 |
| 42 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.38670009 |
| 43 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.37603867 |
| 44 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.32228178 |
| 45 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.29942619 |
| 46 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.28938886 |
| 47 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.28278859 |
| 48 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.27726077 |
| 49 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.27041516 |
| 50 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.26853610 |
| 51 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.26329350 |
| 52 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.23964879 |
| 53 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.22609778 |
| 54 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.22594578 |
| 55 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.22421536 |
| 56 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.20207390 |
| 57 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.19635201 |
| 58 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.19543708 |
| 59 | KLF5_25053715_ChIP-Seq_YYC3_Human | 1.19207272 |
| 60 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.19016208 |
| 61 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.18929072 |
| 62 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.17773056 |
| 63 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.17516906 |
| 64 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.15813349 |
| 65 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.13373259 |
| 66 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.12690804 |
| 67 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.12463989 |
| 68 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.11073631 |
| 69 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.10433878 |
| 70 | MAF_26560356_Chip-Seq_TH2_Human | 1.08867635 |
| 71 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 1.08094307 |
| 72 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 1.07982769 |
| 73 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.07719499 |
| 74 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.06387365 |
| 75 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.06234303 |
| 76 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.03967059 |
| 77 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.03331903 |
| 78 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01950890 |
| 79 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.99873945 |
| 80 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.98692805 |
| 81 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.98469168 |
| 82 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.97902486 |
| 83 | SA1_27219007_Chip-Seq_Bcells_Human | 0.97635368 |
| 84 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.95873869 |
| 85 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.95162054 |
| 86 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.93937335 |
| 87 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.93264489 |
| 88 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.93067108 |
| 89 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.91787126 |
| 90 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.89042009 |
| 91 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.88294026 |
| 92 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87936957 |
| 93 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.87638907 |
| 94 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.87457075 |
| 95 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.87307487 |
| 96 | ERA_21632823_ChIP-Seq_H3396_Human | 0.86703043 |
| 97 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.86670385 |
| 98 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.86407939 |
| 99 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.85645909 |
| 100 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.84824021 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009384_cardiac_valve_regurgitation | 5.69007054 |
| 2 | MP0001849_ear_inflammation | 4.83113969 |
| 3 | MP0003172_abnormal_lysosome_physiology | 4.21278719 |
| 4 | MP0005083_abnormal_biliary_tract | 4.12569407 |
| 5 | MP0005058_abnormal_lysosome_morphology | 4.07974461 |
| 6 | MP0004084_abnormal_cardiac_muscle | 3.71725750 |
| 7 | MP0004381_abnormal_hair_follicle | 3.15429111 |
| 8 | MP0002249_abnormal_larynx_morphology | 3.06789947 |
| 9 | MP0005503_abnormal_tendon_morphology | 3.02809534 |
| 10 | MP0000013_abnormal_adipose_tissue | 2.78157813 |
| 11 | MP0008260_abnormal_autophagy | 2.66267446 |
| 12 | MP0002822_catalepsy | 2.66221389 |
| 13 | MP0003705_abnormal_hypodermis_morpholog | 2.51413590 |
| 14 | MP0005275_abnormal_skin_tensile | 2.49422407 |
| 15 | MP0001958_emphysema | 2.48615273 |
| 16 | MP0006138_congestive_heart_failure | 2.47816626 |
| 17 | MP0008438_abnormal_cutaneous_collagen | 2.40909994 |
| 18 | MP0000767_abnormal_smooth_muscle | 2.27374571 |
| 19 | MP0001348_abnormal_lacrimal_gland | 2.24991296 |
| 20 | MP0003279_aneurysm | 2.15010628 |
| 21 | MP0001299_abnormal_eye_distance/ | 2.10732870 |
| 22 | MP0001502_abnormal_circadian_rhythm | 2.00097094 |
| 23 | MP0005670_abnormal_white_adipose | 1.99716935 |
| 24 | MP0004036_abnormal_muscle_relaxation | 1.98938132 |
| 25 | MP0002933_joint_inflammation | 1.98022553 |
| 26 | MP0000751_myopathy | 1.87359749 |
| 27 | MP0002932_abnormal_joint_morphology | 1.85048876 |
| 28 | MP0005377_hearing/vestibular/ear_phenot | 1.79925132 |
| 29 | MP0003878_abnormal_ear_physiology | 1.79925132 |
| 30 | MP0000371_diluted_coat_color | 1.78748734 |
| 31 | MP0005360_urolithiasis | 1.75776275 |
| 32 | MP0000003_abnormal_adipose_tissue | 1.72904859 |
| 33 | MP0009780_abnormal_chondrocyte_physiolo | 1.62582758 |
| 34 | MP0000678_abnormal_parathyroid_gland | 1.59688585 |
| 35 | MP0000733_abnormal_muscle_development | 1.56447628 |
| 36 | MP0010368_abnormal_lymphatic_system | 1.50817681 |
| 37 | MP0005409_darkened_coat_color | 1.36311020 |
| 38 | MP0002108_abnormal_muscle_morphology | 1.30761661 |
| 39 | MP0003879_abnormal_hair_cell | 1.27033227 |
| 40 | MP0001764_abnormal_homeostasis | 1.26092443 |
| 41 | MP0003136_yellow_coat_color | 1.23765613 |
| 42 | MP0005375_adipose_tissue_phenotype | 1.21961519 |
| 43 | MP0003183_abnormal_peptide_metabolism | 1.19428734 |
| 44 | MP0003690_abnormal_glial_cell | 1.17929488 |
| 45 | MP0002060_abnormal_skin_morphology | 1.11301873 |
| 46 | MP0002796_impaired_skin_barrier | 1.10318878 |
| 47 | MP0002282_abnormal_trachea_morphology | 1.07064506 |
| 48 | MP0000681_abnormal_thyroid_gland | 1.03356861 |
| 49 | MP0003045_fibrosis | 1.02965463 |
| 50 | MP0000383_abnormal_hair_follicle | 1.00479030 |
| 51 | MP0002653_abnormal_ependyma_morphology | 0.97703874 |
| 52 | MP0003137_abnormal_impulse_conducting | 0.97654889 |
| 53 | MP0000163_abnormal_cartilage_morphology | 0.96167349 |
| 54 | MP0005410_abnormal_fertilization | 0.93936159 |
| 55 | MP0001873_stomach_inflammation | 0.93784450 |
| 56 | MP0002116_abnormal_craniofacial_bone | 0.87600973 |
| 57 | MP0003942_abnormal_urinary_system | 0.86143432 |
| 58 | MP0005508_abnormal_skeleton_morphology | 0.85872541 |
| 59 | MP0001879_abnormal_lymphatic_vessel | 0.83270674 |
| 60 | MP0002132_abnormal_respiratory_system | 0.82900824 |
| 61 | MP0004264_abnormal_extraembryonic_tissu | 0.81877594 |
| 62 | MP0005535_abnormal_body_temperature | 0.80028893 |
| 63 | MP0000026_abnormal_inner_ear | 0.78480774 |
| 64 | MP0005666_abnormal_adipose_tissue | 0.77562068 |
| 65 | MP0005076_abnormal_cell_differentiation | 0.77540691 |
| 66 | MP0002970_abnormal_white_adipose | 0.76263857 |
| 67 | MP0005075_abnormal_melanosome_morpholog | 0.75794956 |
| 68 | MP0010030_abnormal_orbit_morphology | 0.73219699 |
| 69 | MP0000428_abnormal_craniofacial_morphol | 0.71561538 |
| 70 | MP0002166_altered_tumor_susceptibility | 0.71008447 |
| 71 | MP0002896_abnormal_bone_mineralization | 0.70042760 |
| 72 | MP0003938_abnormal_ear_development | 0.68695312 |
| 73 | MP0004043_abnormal_pH_regulation | 0.65438384 |
| 74 | MP0002115_abnormal_skeleton_extremities | 0.64400956 |
| 75 | MP0005501_abnormal_skin_physiology | 0.63582248 |
| 76 | MP0002177_abnormal_outer_ear | 0.63524419 |
| 77 | MP0001765_abnormal_ion_homeostasis | 0.63374142 |
| 78 | MP0002998_abnormal_bone_remodeling | 0.62814934 |
| 79 | MP0000427_abnormal_hair_cycle | 0.62087240 |
| 80 | MP0000230_abnormal_systemic_arterial | 0.61686934 |
| 81 | MP0002254_reproductive_system_inflammat | 0.61361909 |
| 82 | MP0001664_abnormal_digestion | 0.60565901 |
| 83 | MP0000627_abnormal_mammary_gland | 0.58507962 |
| 84 | MP0008004_abnormal_stomach_pH | 0.58253678 |
| 85 | MP0000249_abnormal_blood_vessel | 0.57998044 |
| 86 | MP0002075_abnormal_coat/hair_pigmentati | 0.57717052 |
| 87 | MP0002114_abnormal_axial_skeleton | 0.56937246 |
| 88 | MP0003795_abnormal_bone_structure | 0.56356429 |
| 89 | MP0002113_abnormal_skeleton_development | 0.55197576 |
| 90 | MP0001614_abnormal_blood_vessel | 0.54758315 |
| 91 | MP0002128_abnormal_blood_circulation | 0.54668276 |
| 92 | MP0003724_increased_susceptibility_to | 0.53391696 |
| 93 | MP0003091_abnormal_cell_migration | 0.53065844 |
| 94 | MP0005023_abnormal_wound_healing | 0.52597235 |
| 95 | MP0009643_abnormal_urine_homeostasis | 0.51679118 |
| 96 | MP0010771_integument_phenotype | 0.51619643 |
| 97 | MP0001243_abnormal_dermal_layer | 0.51466126 |
| 98 | MP0000538_abnormal_urinary_bladder | 0.49704511 |
| 99 | MP0000566_synostosis | 0.49300694 |
| 100 | MP0002127_abnormal_cardiovascular_syste | 0.49127551 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | J-shaped sella turcica (HP:0002680) | 8.69823857 |
| 2 | Cervical subluxation (HP:0003308) | 7.98487488 |
| 3 | Obstructive sleep apnea (HP:0002870) | 7.29370378 |
| 4 | Broad face (HP:0000283) | 7.25791571 |
| 5 | Aortic regurgitation (HP:0001659) | 6.69467321 |
| 6 | Abnormality of lateral ventricle (HP:0030047) | 5.35190777 |
| 7 | Deformed sella turcica (HP:0002681) | 4.92137583 |
| 8 | Stridor (HP:0010307) | 4.91752418 |
| 9 | Biconcave vertebral bodies (HP:0004586) | 4.85974261 |
| 10 | Lymphangioma (HP:0100764) | 4.28537536 |
| 11 | Delayed CNS myelination (HP:0002188) | 4.14717508 |
| 12 | Vitreoretinal degeneration (HP:0000655) | 4.03229645 |
| 13 | Flared iliac wings (HP:0002869) | 4.02961094 |
| 14 | Neurodegeneration (HP:0002180) | 3.86061207 |
| 15 | Neoplasm of the heart (HP:0100544) | 3.78717931 |
| 16 | Joint stiffness (HP:0001387) | 3.74570080 |
| 17 | Nuclear cataract (HP:0100018) | 3.73838286 |
| 18 | Ependymoma (HP:0002888) | 3.73783927 |
| 19 | Mucopolysacchariduria (HP:0008155) | 3.72977977 |
| 20 | Urinary glycosaminoglycan excretion (HP:0003541) | 3.72977977 |
| 21 | Aortic valve stenosis (HP:0001650) | 3.69155769 |
| 22 | Dysostosis multiplex (HP:0000943) | 3.65236341 |
| 23 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 3.59568576 |
| 24 | Abnormality of polysaccharide metabolism (HP:0011012) | 3.59568576 |
| 25 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 3.59568576 |
| 26 | Cerebral palsy (HP:0100021) | 3.52112944 |
| 27 | Severe Myopia (HP:0011003) | 3.50501310 |
| 28 | Hypoplasia of the odontoid process (HP:0003311) | 3.37895169 |
| 29 | Spinal canal stenosis (HP:0003416) | 3.35944036 |
| 30 | Abnormality of the sella turcica (HP:0002679) | 3.32476156 |
| 31 | Sleep apnea (HP:0010535) | 3.28837664 |
| 32 | Tubulointerstitial nephritis (HP:0001970) | 3.19464908 |
| 33 | Mitral regurgitation (HP:0001653) | 3.17001495 |
| 34 | Generalized hypopigmentation of hair (HP:0011358) | 3.15367078 |
| 35 | Thin bony cortex (HP:0002753) | 3.09823360 |
| 36 | Bundle branch block (HP:0011710) | 3.01535055 |
| 37 | Abnormality of the femoral head (HP:0003368) | 2.92091735 |
| 38 | Short clavicles (HP:0000894) | 2.89628831 |
| 39 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 2.89337053 |
| 40 | Abnormality of the odontoid process (HP:0003310) | 2.80694194 |
| 41 | Broad metatarsal (HP:0001783) | 2.76455190 |
| 42 | Astrocytoma (HP:0009592) | 2.71503296 |
| 43 | Abnormality of the astrocytes (HP:0100707) | 2.71503296 |
| 44 | Tracheal stenosis (HP:0002777) | 2.68118434 |
| 45 | Flattened epiphyses (HP:0003071) | 2.64962700 |
| 46 | Ocular albinism (HP:0001107) | 2.62220979 |
| 47 | Cerebral aneurysm (HP:0004944) | 2.61657381 |
| 48 | Metaphyseal cupping (HP:0003021) | 2.58926721 |
| 49 | Easy fatigability (HP:0003388) | 2.56399883 |
| 50 | Mild short stature (HP:0003502) | 2.56168673 |
| 51 | Aplasia/Hypoplasia of the clavicles (HP:0006710) | 2.53685022 |
| 52 | Hypoplastic ischia (HP:0003175) | 2.50058437 |
| 53 | Visceral angiomatosis (HP:0100761) | 2.45072909 |
| 54 | Renal dysplasia (HP:0000110) | 2.43500363 |
| 55 | Coxa valga (HP:0002673) | 2.37034573 |
| 56 | Prolonged QT interval (HP:0001657) | 2.32649040 |
| 57 | Hamartoma of the eye (HP:0010568) | 2.30028261 |
| 58 | Bronchomalacia (HP:0002780) | 2.28783202 |
| 59 | Aplasia/hypoplasia of the femur (HP:0005613) | 2.27744267 |
| 60 | Infantile muscular hypotonia (HP:0008947) | 2.27537390 |
| 61 | Shallow orbits (HP:0000586) | 2.26390261 |
| 62 | Hemangiomatosis (HP:0007461) | 2.26231174 |
| 63 | Aplasia/Hypoplasia involving the pelvis (HP:0009103) | 2.25273101 |
| 64 | Atelectasis (HP:0100750) | 2.20639583 |
| 65 | Abnormality of the ischium (HP:0003174) | 2.18782707 |
| 66 | Broad nasal tip (HP:0000455) | 2.18397139 |
| 67 | Increased connective tissue (HP:0009025) | 2.13092570 |
| 68 | Iris hypopigmentation (HP:0007730) | 2.12767407 |
| 69 | Bradycardia (HP:0001662) | 2.08079887 |
| 70 | Wide nose (HP:0000445) | 2.01778356 |
| 71 | Bell-shaped thorax (HP:0001591) | 2.01224209 |
| 72 | Aneurysm (HP:0002617) | 2.00781834 |
| 73 | Pulmonary artery stenosis (HP:0004415) | 1.99866699 |
| 74 | Hepatosplenomegaly (HP:0001433) | 1.92564276 |
| 75 | Abnormal atrioventricular conduction (HP:0005150) | 1.89883452 |
| 76 | Heart block (HP:0012722) | 1.89639552 |
| 77 | Tubular atrophy (HP:0000092) | 1.88639079 |
| 78 | Generalized hypopigmentation (HP:0007513) | 1.87093627 |
| 79 | Emphysema (HP:0002097) | 1.80833601 |
| 80 | Hypertriglyceridemia (HP:0002155) | 1.80280551 |
| 81 | Concave nail (HP:0001598) | 1.78133637 |
| 82 | Glioma (HP:0009733) | 1.76317407 |
| 83 | Sparse lateral eyebrow (HP:0005338) | 1.73813499 |
| 84 | Pulmonary hypertension (HP:0002092) | 1.70146481 |
| 85 | Nonimmune hydrops fetalis (HP:0001790) | 1.70055636 |
| 86 | Soft skin (HP:0000977) | 1.69476611 |
| 87 | Hyperacusis (HP:0010780) | 1.63108946 |
| 88 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.62854236 |
| 89 | Spinal rigidity (HP:0003306) | 1.62769898 |
| 90 | Skin nodule (HP:0200036) | 1.62105650 |
| 91 | Aortic aneurysm (HP:0004942) | 1.61599714 |
| 92 | Renal salt wasting (HP:0000127) | 1.57269150 |
| 93 | Stage 5 chronic kidney disease (HP:0003774) | 1.55962541 |
| 94 | Progressive neurologic deterioration (HP:0002344) | 1.54775435 |
| 95 | Microdontia (HP:0000691) | 1.54251720 |
| 96 | Syncope (HP:0001279) | 1.53846506 |
| 97 | Protrusio acetabuli (HP:0003179) | 1.53150422 |
| 98 | Aplasia/Hypoplasia involving the vertebral column (HP:0008518) | 1.52661839 |
| 99 | Osteoarthritis (HP:0002758) | 1.52023936 |
| 100 | Difficulty running (HP:0009046) | 1.51199771 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TNK2 | 5.35841551 |
| 2 | NME1 | 4.76434868 |
| 3 | TRIB3 | 4.37747559 |
| 4 | SIK1 | 3.41502187 |
| 5 | BMX | 2.94943428 |
| 6 | ERBB2 | 2.92998796 |
| 7 | KDR | 2.84441824 |
| 8 | MAP2K6 | 2.47816404 |
| 9 | PKN2 | 2.30625385 |
| 10 | MAP3K7 | 2.27305001 |
| 11 | RPS6KA2 | 2.26162000 |
| 12 | MST1R | 2.12898250 |
| 13 | MARK2 | 1.98694898 |
| 14 | RPS6KL1 | 1.95916093 |
| 15 | RPS6KC1 | 1.95916093 |
| 16 | MAPK15 | 1.86302569 |
| 17 | ERN1 | 1.83126287 |
| 18 | RPS6KA6 | 1.76886888 |
| 19 | MAP3K6 | 1.75027212 |
| 20 | ZAP70 | 1.59346322 |
| 21 | NTRK3 | 1.59038066 |
| 22 | MUSK | 1.52588129 |
| 23 | RIPK1 | 1.51242174 |
| 24 | EEF2K | 1.50304677 |
| 25 | TESK1 | 1.46770036 |
| 26 | MAP3K13 | 1.35289429 |
| 27 | PDGFRB | 1.28723091 |
| 28 | MAPK7 | 1.27583125 |
| 29 | IKBKE | 1.23581374 |
| 30 | HIPK2 | 1.21940518 |
| 31 | EPHA2 | 1.18473307 |
| 32 | TBK1 | 1.17768521 |
| 33 | PRKD2 | 1.13359661 |
| 34 | MET | 1.10173000 |
| 35 | MTOR | 1.09644777 |
| 36 | CHUK | 1.04447433 |
| 37 | PTK6 | 1.03546375 |
| 38 | FER | 0.93995767 |
| 39 | PTK2B | 0.92636074 |
| 40 | PRKCI | 0.91089480 |
| 41 | PDGFRA | 0.89683350 |
| 42 | NEK6 | 0.89308111 |
| 43 | STK38 | 0.88761986 |
| 44 | PAK4 | 0.87911226 |
| 45 | MAP4K1 | 0.86783131 |
| 46 | SIK2 | 0.85015311 |
| 47 | TLK1 | 0.84159838 |
| 48 | CAMK1 | 0.83430627 |
| 49 | PRKAA2 | 0.81215883 |
| 50 | PTK2 | 0.80985463 |
| 51 | PRKAA1 | 0.78828918 |
| 52 | MYLK | 0.78809735 |
| 53 | TIE1 | 0.76452265 |
| 54 | PINK1 | 0.76118470 |
| 55 | ROCK1 | 0.74409823 |
| 56 | PRKD1 | 0.73810027 |
| 57 | MAPK8 | 0.72017225 |
| 58 | INSRR | 0.70575685 |
| 59 | MARK3 | 0.70568741 |
| 60 | CDC42BPA | 0.70428186 |
| 61 | MAP3K14 | 0.68073210 |
| 62 | MAPKAPK3 | 0.61715818 |
| 63 | MAPK4 | 0.57057304 |
| 64 | MAPK3 | 0.54899269 |
| 65 | TEC | 0.53049394 |
| 66 | FRK | 0.51219608 |
| 67 | GRK6 | 0.51190661 |
| 68 | PRKD3 | 0.50277343 |
| 69 | SIK3 | 0.49751107 |
| 70 | RPS6KA1 | 0.48598162 |
| 71 | MAPK1 | 0.48313337 |
| 72 | STK39 | 0.47042277 |
| 73 | RIPK4 | 0.46861618 |
| 74 | WNK4 | 0.44813171 |
| 75 | MAPK10 | 0.44269821 |
| 76 | EPHB1 | 0.43901061 |
| 77 | DYRK1B | 0.43737151 |
| 78 | MAP3K11 | 0.38629440 |
| 79 | ICK | 0.38450619 |
| 80 | MATK | 0.37443937 |
| 81 | TYK2 | 0.36784726 |
| 82 | TGFBR2 | 0.35717043 |
| 83 | OXSR1 | 0.35579054 |
| 84 | MAPK12 | 0.35473330 |
| 85 | PKN1 | 0.33537399 |
| 86 | PDPK1 | 0.33165257 |
| 87 | KIT | 0.32976435 |
| 88 | FGFR4 | 0.32784716 |
| 89 | CAMKK1 | 0.32589021 |
| 90 | JAK3 | 0.32283599 |
| 91 | MAPKAPK2 | 0.32266834 |
| 92 | CDK3 | 0.32181448 |
| 93 | IKBKB | 0.30922655 |
| 94 | SRC | 0.30645428 |
| 95 | RPS6KA5 | 0.30487730 |
| 96 | STK38L | 0.30029923 |
| 97 | JAK1 | 0.29740469 |
| 98 | DDR2 | 0.28631965 |
| 99 | MAP3K10 | 0.27870013 |
| 100 | ILK | 0.27640636 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 4.95051018 |
| 2 | Notch signaling pathway_Homo sapiens_hsa04330 | 3.77252295 |
| 3 | Other glycan degradation_Homo sapiens_hsa00511 | 3.32382879 |
| 4 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 2.89482436 |
| 5 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 2.45145406 |
| 6 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.37120908 |
| 7 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.07330366 |
| 8 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.96485031 |
| 9 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.95350855 |
| 10 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.86629132 |
| 11 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.85253560 |
| 12 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.82815258 |
| 13 | ABC transporters_Homo sapiens_hsa02010 | 1.76380859 |
| 14 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.73304328 |
| 15 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.64415663 |
| 16 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.63614216 |
| 17 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.61222528 |
| 18 | Focal adhesion_Homo sapiens_hsa04510 | 1.56345753 |
| 19 | Tight junction_Homo sapiens_hsa04530 | 1.34346111 |
| 20 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.31647718 |
| 21 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.28497757 |
| 22 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.25251190 |
| 23 | AMPK signaling pathway_Homo sapiens_hsa04152 | 1.24634206 |
| 24 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.24007518 |
| 25 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.21230992 |
| 26 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.16668584 |
| 27 | Lysine degradation_Homo sapiens_hsa00310 | 1.14780947 |
| 28 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.14296422 |
| 29 | Axon guidance_Homo sapiens_hsa04360 | 1.09668028 |
| 30 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.06274050 |
| 31 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.05838540 |
| 32 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.03218652 |
| 33 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.02495885 |
| 34 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.02329439 |
| 35 | Insulin secretion_Homo sapiens_hsa04911 | 1.00990998 |
| 36 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.94400323 |
| 37 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.91722749 |
| 38 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.91093418 |
| 39 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.85186086 |
| 40 | Insulin resistance_Homo sapiens_hsa04931 | 0.84901105 |
| 41 | Endocytosis_Homo sapiens_hsa04144 | 0.83428018 |
| 42 | Platelet activation_Homo sapiens_hsa04611 | 0.83142229 |
| 43 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.82587167 |
| 44 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.82143979 |
| 45 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.82084892 |
| 46 | Lysosome_Homo sapiens_hsa04142 | 0.80945007 |
| 47 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.76264120 |
| 48 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.75977764 |
| 49 | Gap junction_Homo sapiens_hsa04540 | 0.74811119 |
| 50 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.71624283 |
| 51 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.70390082 |
| 52 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.67284911 |
| 53 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.67135226 |
| 54 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.63447617 |
| 55 | Melanogenesis_Homo sapiens_hsa04916 | 0.63200750 |
| 56 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.62979930 |
| 57 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.62385672 |
| 58 | Circadian rhythm_Homo sapiens_hsa04710 | 0.62215402 |
| 59 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.59609625 |
| 60 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.58478230 |
| 61 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.56963383 |
| 62 | Hepatitis C_Homo sapiens_hsa05160 | 0.56385470 |
| 63 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.56142233 |
| 64 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.56047246 |
| 65 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.54864486 |
| 66 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.54510126 |
| 67 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.53535086 |
| 68 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.52446672 |
| 69 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.51622485 |
| 70 | Prostate cancer_Homo sapiens_hsa05215 | 0.50825266 |
| 71 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.50513960 |
| 72 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.50194222 |
| 73 | Bile secretion_Homo sapiens_hsa04976 | 0.48457916 |
| 74 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.48346741 |
| 75 | Malaria_Homo sapiens_hsa05144 | 0.48213225 |
| 76 | Renin secretion_Homo sapiens_hsa04924 | 0.47996241 |
| 77 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.47287990 |
| 78 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.46823855 |
| 79 | Taste transduction_Homo sapiens_hsa04742 | 0.44451712 |
| 80 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.44318983 |
| 81 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.43602301 |
| 82 | Salivary secretion_Homo sapiens_hsa04970 | 0.41581084 |
| 83 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.41386263 |
| 84 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.41106357 |
| 85 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.39573293 |
| 86 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.39077658 |
| 87 | Apoptosis_Homo sapiens_hsa04210 | 0.38449071 |
| 88 | Circadian entrainment_Homo sapiens_hsa04713 | 0.37376654 |
| 89 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.37030174 |
| 90 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.36855842 |
| 91 | Glioma_Homo sapiens_hsa05214 | 0.35904640 |
| 92 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.35641209 |
| 93 | Pathways in cancer_Homo sapiens_hsa05200 | 0.33664815 |
| 94 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.33647178 |
| 95 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.32885852 |
| 96 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.32394548 |
| 97 | Endometrial cancer_Homo sapiens_hsa05213 | 0.30845538 |
| 98 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.30536497 |
| 99 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.29885378 |
| 100 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.29881052 |

