AUNIP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)5.46135249
2DNA strand elongation involved in DNA replication (GO:0006271)5.25478638
3DNA replication initiation (GO:0006270)5.14572189
4DNA replication checkpoint (GO:0000076)5.03053970
5DNA strand elongation (GO:0022616)4.98816239
6mitotic metaphase plate congression (GO:0007080)4.92033928
7telomere maintenance via semi-conservative replication (GO:0032201)4.90610310
8DNA unwinding involved in DNA replication (GO:0006268)4.87390914
9protein localization to chromosome, centromeric region (GO:0071459)4.70679125
10telomere maintenance via recombination (GO:0000722)4.40266930
11mitotic nuclear envelope disassembly (GO:0007077)4.31469945
12mitotic recombination (GO:0006312)4.25533150
13metaphase plate congression (GO:0051310)4.25006091
14DNA replication-dependent nucleosome organization (GO:0034723)4.24693163
15DNA replication-dependent nucleosome assembly (GO:0006335)4.24693163
16mitotic sister chromatid segregation (GO:0000070)4.22855716
17CENP-A containing nucleosome assembly (GO:0034080)4.22466929
18regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.20699847
19chromatin remodeling at centromere (GO:0031055)4.20182925
20mitotic chromosome condensation (GO:0007076)4.12491877
21nucleobase biosynthetic process (GO:0046112)4.06132373
22formation of translation preinitiation complex (GO:0001731)4.00656321
23nuclear envelope disassembly (GO:0051081)4.00565164
24membrane disassembly (GO:0030397)4.00565164
25kinetochore organization (GO:0051383)4.00230003
26ribosome assembly (GO:0042255)3.96692131
27attachment of spindle microtubules to kinetochore (GO:0008608)3.95093926
28DNA replication-independent nucleosome organization (GO:0034724)3.91878588
29DNA replication-independent nucleosome assembly (GO:0006336)3.91878588
30regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.91540079
31telomere maintenance via telomere lengthening (GO:0010833)3.87653594
32folic acid-containing compound biosynthetic process (GO:0009396)3.83229817
33nucleotide-excision repair, DNA gap filling (GO:0006297)3.82827188
34establishment of chromosome localization (GO:0051303)3.80526232
35kinetochore assembly (GO:0051382)3.78413984
36purine nucleobase biosynthetic process (GO:0009113)3.78178082
37pseudouridine synthesis (GO:0001522)3.78172385
38regulation of spindle organization (GO:0090224)3.77173159
39sister chromatid segregation (GO:0000819)3.76119550
40maturation of SSU-rRNA (GO:0030490)3.72958528
41DNA deamination (GO:0045006)3.71695843
42positive regulation of chromosome segregation (GO:0051984)3.71507927
43histone exchange (GO:0043486)3.68399308
44nuclear pore organization (GO:0006999)3.58578045
45replication fork processing (GO:0031297)3.57516280
46synapsis (GO:0007129)3.57375763
47ribosome biogenesis (GO:0042254)3.54813169
48resolution of meiotic recombination intermediates (GO:0000712)3.53316707
49spindle checkpoint (GO:0031577)3.48296501
50protein localization to chromosome (GO:0034502)3.47129248
51regulation of chromosome segregation (GO:0051983)3.46846489
52somatic diversification of immune receptors via somatic mutation (GO:0002566)3.43199370
53somatic hypermutation of immunoglobulin genes (GO:0016446)3.43199370
54negative regulation of chromosome segregation (GO:0051985)3.42842373
55meiotic chromosome segregation (GO:0045132)3.41542961
56maturation of 5.8S rRNA (GO:0000460)3.41189954
57protein K6-linked ubiquitination (GO:0085020)3.40069801
58IMP biosynthetic process (GO:0006188)3.38000436
59establishment of protein localization to mitochondrial membrane (GO:0090151)3.37844479
60regulation of double-strand break repair via homologous recombination (GO:0010569)3.37702060
61nuclear pore complex assembly (GO:0051292)3.35635309
62negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.34660800
63negative regulation of sister chromatid segregation (GO:0033046)3.34660800
64negative regulation of mitotic sister chromatid separation (GO:2000816)3.34660800
65negative regulation of mitotic sister chromatid segregation (GO:0033048)3.34660800
66regulation of mitochondrial translation (GO:0070129)3.34621834
67chromatin assembly or disassembly (GO:0006333)3.33556941
68negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.33301300
69regulation of centrosome cycle (GO:0046605)3.29646324
70mitochondrial RNA metabolic process (GO:0000959)3.29618140
71spindle assembly checkpoint (GO:0071173)3.27630402
72regulation of mitotic metaphase/anaphase transition (GO:0030071)3.24499538
73regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.23679952
74maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.23553703
75ribonucleoprotein complex biogenesis (GO:0022613)3.23507292
76mitotic spindle assembly checkpoint (GO:0007094)3.23469185
77chromosome segregation (GO:0007059)3.23254421
78folic acid metabolic process (GO:0046655)3.22722244
79mitotic spindle checkpoint (GO:0071174)3.20908474
80DNA duplex unwinding (GO:0032508)3.20141442
81DNA geometric change (GO:0032392)3.18621054
82translesion synthesis (GO:0019985)3.17716603
83nuclear envelope organization (GO:0006998)3.17412053
84ribosomal small subunit assembly (GO:0000028)3.17309362
85spliceosomal snRNP assembly (GO:0000387)3.16481764
86negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.16073548
87IMP metabolic process (GO:0046040)3.15024364
88regulation of centriole replication (GO:0046599)3.13939326
89rRNA processing (GO:0006364)3.13933625
90mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.13808368
91DNA catabolic process, exonucleolytic (GO:0000738)3.12862526
92rRNA methylation (GO:0031167)3.12400894
93regulation of mitotic spindle organization (GO:0060236)3.11675165
94negative regulation of DNA-dependent DNA replication (GO:2000104)3.10950181
95regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.09829858
96ribosomal large subunit biogenesis (GO:0042273)3.09036782
97postreplication repair (GO:0006301)3.08826418
98transcription-coupled nucleotide-excision repair (GO:0006283)3.08295897
99DNA double-strand break processing (GO:0000729)3.08022942
100regulation of sister chromatid segregation (GO:0033045)3.07517687
101regulation of mitotic sister chromatid separation (GO:0010965)3.07517687
102regulation of mitotic sister chromatid segregation (GO:0033047)3.07517687
103mismatch repair (GO:0006298)3.06025688
104rRNA modification (GO:0000154)3.05815670
105regulation of sister chromatid cohesion (GO:0007063)3.04614426
106ATP-dependent chromatin remodeling (GO:0043044)3.03884492
107rRNA metabolic process (GO:0016072)3.03629331
108anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.03290513
109translational initiation (GO:0006413)3.01549081
110positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.01427192
111positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.01427192
112positive regulation of mitotic sister chromatid separation (GO:1901970)3.01427192
113exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.99833741
114regulation of nuclear cell cycle DNA replication (GO:0033262)2.99731451
115establishment of integrated proviral latency (GO:0075713)2.99577397
116proteasome assembly (GO:0043248)2.99531648
117translational termination (GO:0006415)2.98509112
118mitotic cell cycle (GO:0000278)2.98464327
119tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.95146777
120RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.95146777
121pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.95004402
122positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.92100713
123nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.91698846
124DNA ligation (GO:0006266)2.91355971
125negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.89068701
126negative regulation of ligase activity (GO:0051352)2.89068701
127mitochondrial respiratory chain complex assembly (GO:0033108)2.89011816
128positive regulation of histone H3-K4 methylation (GO:0051571)2.87146034
129peptidyl-histidine modification (GO:0018202)2.87019499
130chaperone-mediated protein transport (GO:0072321)2.86554905
131termination of RNA polymerase III transcription (GO:0006386)2.85698841
132transcription elongation from RNA polymerase III promoter (GO:0006385)2.85698841
133DNA topological change (GO:0006265)2.83240399
134ATP synthesis coupled proton transport (GO:0015986)2.82456639
135energy coupled proton transport, down electrochemical gradient (GO:0015985)2.82456639

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.63493328
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.84678325
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.08176418
4E2F4_17652178_ChIP-ChIP_JURKAT_Human4.00659238
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.61466599
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.48063694
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.93626247
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.92743651
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.73844354
10MYC_18358816_ChIP-ChIP_MESCs_Mouse2.73664095
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.67937470
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.61312665
13JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.57796364
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.53280117
15AR_21909140_ChIP-Seq_LNCAP_Human2.52164663
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.50577950
17GABP_17652178_ChIP-ChIP_JURKAT_Human2.50470609
18NELFA_20434984_ChIP-Seq_ESCs_Mouse2.32864237
19XRN2_22483619_ChIP-Seq_HELA_Human2.20996909
20E2F1_21310950_ChIP-Seq_MCF-7_Human2.17426475
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.12078594
22VDR_23849224_ChIP-Seq_CD4+_Human2.04044281
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.02119100
24MYCN_18555785_ChIP-Seq_MESCs_Mouse1.95774980
25E2F1_18555785_ChIP-Seq_MESCs_Mouse1.92898612
26MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.92230773
27NANOG_18555785_ChIP-Seq_MESCs_Mouse1.89178067
28NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.88295591
29GABP_19822575_ChIP-Seq_HepG2_Human1.81539896
30FOXP3_21729870_ChIP-Seq_TREG_Human1.81275508
31DCP1A_22483619_ChIP-Seq_HELA_Human1.79563507
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.75724068
33KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.72815154
34POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.72695297
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.71190201
36TTF2_22483619_ChIP-Seq_HELA_Human1.70073372
37THAP11_20581084_ChIP-Seq_MESCs_Mouse1.66844906
38ZNF274_21170338_ChIP-Seq_K562_Hela1.62969061
39MYC_22102868_ChIP-Seq_BL_Human1.59788109
40EGR1_19374776_ChIP-ChIP_THP-1_Human1.59606948
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.58017613
42HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.56606359
43SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.53711324
44CIITA_25753668_ChIP-Seq_RAJI_Human1.52506408
45ZFX_18555785_ChIP-Seq_MESCs_Mouse1.49802469
46KDM5A_27292631_Chip-Seq_BREAST_Human1.45359746
47YY1_21170310_ChIP-Seq_MESCs_Mouse1.42442748
48ELF1_17652178_ChIP-ChIP_JURKAT_Human1.41493743
49POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.39893081
50SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.39603739
51YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.37566879
52TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.35030825
53ELK1_19687146_ChIP-ChIP_HELA_Human1.32523875
54VDR_22108803_ChIP-Seq_LS180_Human1.32158046
55FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.31211440
56EWS_26573619_Chip-Seq_HEK293_Human1.31049612
57CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.30221059
58KLF4_18555785_ChIP-Seq_MESCs_Mouse1.29538720
59HOXB4_20404135_ChIP-ChIP_EML_Mouse1.29461516
60POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.28268279
61ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.27687878
62STAT3_1855785_ChIP-Seq_MESCs_Mouse1.26062847
63CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.26035320
64IRF1_19129219_ChIP-ChIP_H3396_Human1.25378708
65SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.23426292
66HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.22349854
67DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.22030576
68E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.21569055
69SRF_21415370_ChIP-Seq_HL-1_Mouse1.16985224
70CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.15926242
71SOX2_18555785_ChIP-Seq_MESCs_Mouse1.14706354
72SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13513451
73TP63_19390658_ChIP-ChIP_HaCaT_Human1.08528641
74ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.06462544
75CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.05512600
76PADI4_21655091_ChIP-ChIP_MCF-7_Human1.05336870
77KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.05253909
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.04071885
79FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.01996884
80CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.01922678
81TFEB_21752829_ChIP-Seq_HELA_Human1.00636717
82CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.00245230
83VDR_21846776_ChIP-Seq_THP-1_Human0.99444132
84POU5F1_16153702_ChIP-ChIP_HESCs_Human0.97563540
85KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97454527
86NANOG_16153702_ChIP-ChIP_HESCs_Human0.96945569
87SOX2_16153702_ChIP-ChIP_HESCs_Human0.96044017
88MYC_18940864_ChIP-ChIP_HL60_Human0.95899103
89NANOG_21062744_ChIP-ChIP_HESCs_Human0.95030820
90TCF3_18692474_ChIP-Seq_MEFs_Mouse0.93008774
91BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.92598480
92RBPJ_22232070_ChIP-Seq_NCS_Mouse0.91623272
93ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.91515280
94KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.91289359
95KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.91289359
96KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.91289359
97SALL1_21062744_ChIP-ChIP_HESCs_Human0.91130658
98CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.89697091
99PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.88655564
100FUS_26573619_Chip-Seq_HEK293_Human0.88610324
101NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.86044514
102TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.83684990
103ESR1_15608294_ChIP-ChIP_MCF-7_Human0.81656569
104NOTCH1_21737748_ChIP-Seq_TLL_Human0.79966227
105SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.78735293
106OCT4_18692474_ChIP-Seq_MEFs_Mouse0.78244054
107CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.78024878
108TP53_22573176_ChIP-Seq_HFKS_Human0.77561016
109HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.77170461
110GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.76038931
111EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.75437606
112NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.75318407
113NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.74995768
114SOX2_18692474_ChIP-Seq_MEFs_Mouse0.74811592
115SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.74327649
116CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.73828377
117IGF1R_20145208_ChIP-Seq_DFB_Human0.70550175
118SOX17_20123909_ChIP-Seq_XEN_Mouse0.69626027
119SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.69624043
120CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.67125362
121PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.66289534
122TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.63305481
123GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.63265122
124TBX5_21415370_ChIP-Seq_HL-1_Mouse0.59974208

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.94437954
2MP0010094_abnormal_chromosome_stability5.31919787
3MP0003111_abnormal_nucleus_morphology5.00955028
4MP0004957_abnormal_blastocyst_morpholog4.70313038
5MP0003077_abnormal_cell_cycle4.41945450
6MP0008057_abnormal_DNA_replication4.32393467
7MP0008058_abnormal_DNA_repair3.38060869
8MP0008932_abnormal_embryonic_tissue2.93921131
9MP0008877_abnormal_DNA_methylation2.78834698
10MP0008007_abnormal_cellular_replicative2.67339911
11MP0001730_embryonic_growth_arrest2.61821324
12MP0003718_maternal_effect2.59062909
13MP0000350_abnormal_cell_proliferation2.43879438
14MP0003123_paternal_imprinting2.42956245
15MP0004147_increased_porphyrin_level2.42814173
16MP0002396_abnormal_hematopoietic_system2.16375643
17MP0010352_gastrointestinal_tract_polyps2.14430034
18MP0010307_abnormal_tumor_latency2.08463585
19MP0003786_premature_aging1.90063849
20MP0005380_embryogenesis_phenotype1.89803477
21MP0001672_abnormal_embryogenesis/_devel1.89803477
22MP0001697_abnormal_embryo_size1.88938690
23MP0009697_abnormal_copulation1.84756289
24MP0008995_early_reproductive_senescence1.83415216
25MP0000490_abnormal_crypts_of1.74457778
26MP0002080_prenatal_lethality1.70678613
27MP0002085_abnormal_embryonic_tissue1.69844945
28MP0003984_embryonic_growth_retardation1.63793332
29MP0003646_muscle_fatigue1.59913840
30MP0002088_abnormal_embryonic_growth/wei1.59455064
31MP0002210_abnormal_sex_determination1.58350193
32MP0002938_white_spotting1.56645575
33MP0002084_abnormal_developmental_patter1.55499594
34MP0002019_abnormal_tumor_incidence1.55170764
35MP0000313_abnormal_cell_death1.53142771
36MP0002086_abnormal_extraembryonic_tissu1.46836063
37MP0001929_abnormal_gametogenesis1.41986709
38MP0000372_irregular_coat_pigmentation1.41736804
39MP0003806_abnormal_nucleotide_metabolis1.41310758
40MP0002163_abnormal_gland_morphology1.38011499
41MP0001145_abnormal_male_reproductive1.36585251
42MP0000653_abnormal_sex_gland1.30379077
43MP0004197_abnormal_fetal_growth/weight/1.29693271
44MP0003890_abnormal_embryonic-extraembry1.29494888
45MP0010030_abnormal_orbit_morphology1.27791645
46MP0002234_abnormal_pharynx_morphology1.25555835
47MP0004808_abnormal_hematopoietic_stem1.24824443
48MP0001545_abnormal_hematopoietic_system1.22082090
49MP0005397_hematopoietic_system_phenotyp1.22082090
50MP0003941_abnormal_skin_development1.20327955
51MP0003121_genomic_imprinting1.20041592
52MP0002653_abnormal_ependyma_morphology1.19190029
53MP0003136_yellow_coat_color1.17511006
54MP0005076_abnormal_cell_differentiation1.17177266
55MP0003567_abnormal_fetal_cardiomyocyte1.14965218
56MP0009333_abnormal_splenocyte_physiolog1.13077670
57MP0006072_abnormal_retinal_apoptosis1.12962048
58MP0006292_abnormal_olfactory_placode1.12593430
59MP0002736_abnormal_nociception_after1.09578098
60MP0001119_abnormal_female_reproductive1.08175468
61MP0002837_dystrophic_cardiac_calcinosis1.08037746
62MP0003315_abnormal_perineum_morphology1.06764350
63MP0001529_abnormal_vocalization1.05037068
64MP0001346_abnormal_lacrimal_gland1.01268100
65MP0000631_abnormal_neuroendocrine_gland1.00160417
66MP0000703_abnormal_thymus_morphology0.98417059
67MP0001764_abnormal_homeostasis0.96981219
68MP0000647_abnormal_sebaceous_gland0.96852458
69MP0001293_anophthalmia0.96391526
70MP0003699_abnormal_female_reproductive0.94739212
71MP0002160_abnormal_reproductive_system0.90977061
72MP0000358_abnormal_cell_content/0.90848734
73MP0002722_abnormal_immune_system0.89369097
74MP0005410_abnormal_fertilization0.88131045
75MP0003656_abnormal_erythrocyte_physiolo0.87890979
76MP0002398_abnormal_bone_marrow0.87112261
77MP0005384_cellular_phenotype0.85931278
78MP0000689_abnormal_spleen_morphology0.85503195
79MP0005389_reproductive_system_phenotype0.85101808
80MP0005621_abnormal_cell_physiology0.84768823
81MP0005394_taste/olfaction_phenotype0.84606882
82MP0005499_abnormal_olfactory_system0.84606882
83MP0008872_abnormal_physiological_respon0.84540407
84MP0001286_abnormal_eye_development0.83965386
85MP0003119_abnormal_digestive_system0.82467530
86MP0005551_abnormal_eye_electrophysiolog0.80923690
87MP0005646_abnormal_pituitary_gland0.79968705
88MP0002095_abnormal_skin_pigmentation0.78994802
89MP0005379_endocrine/exocrine_gland_phen0.78616537
90MP0003937_abnormal_limbs/digits/tail_de0.78573612
91MP0009672_abnormal_birth_weight0.78160257
92MP0003195_calcinosis0.77567397
93MP0003763_abnormal_thymus_physiology0.77029131
94MP0005395_other_phenotype0.76327647
95MP0002102_abnormal_ear_morphology0.76264768
96MP0002161_abnormal_fertility/fecundity0.75879846
97MP0003186_abnormal_redox_activity0.75227474
98MP0001968_abnormal_touch/_nociception0.75140967
99MP0002111_abnormal_tail_morphology0.74199970
100MP0002132_abnormal_respiratory_system0.73906837
101MP0001915_intracranial_hemorrhage0.73686861
102MP0002233_abnormal_nose_morphology0.72801311
103MP0000049_abnormal_middle_ear0.72637693
104MP0003221_abnormal_cardiomyocyte_apopto0.71506365
105MP0005023_abnormal_wound_healing0.70190467
106MP0005253_abnormal_eye_physiology0.70035941
107MP0000858_altered_metastatic_potential0.69339279
108MP0001919_abnormal_reproductive_system0.68618466
109MP0002429_abnormal_blood_cell0.68083290
110MP0000566_synostosis0.67636703
111MP0003698_abnormal_male_reproductive0.66457091
112MP0002697_abnormal_eye_size0.65172844
113MP0009703_decreased_birth_body0.63833506
114MP0006054_spinal_hemorrhage0.63736428
115MP0005408_hypopigmentation0.63203250
116MP0003705_abnormal_hypodermis_morpholog0.62912271
117MP0001849_ear_inflammation0.62525917
118MP0004133_heterotaxia0.61731054
119MP0005332_abnormal_amino_acid0.61278160
120MP0000537_abnormal_urethra_morphology0.60744934
121MP0001661_extended_life_span0.60742701
122MP0006036_abnormal_mitochondrial_physio0.60655746
123MP0005645_abnormal_hypothalamus_physiol0.60205540
124MP0005075_abnormal_melanosome_morpholog0.60121084
125MP0000477_abnormal_intestine_morphology0.60116832
126MP0009278_abnormal_bone_marrow0.59685446
127MP0000427_abnormal_hair_cycle0.58805729
128MP0000428_abnormal_craniofacial_morphol0.56533443
129MP0003566_abnormal_cell_adhesion0.56227929
130MP0009379_abnormal_foot_pigmentation0.56018580
131MP0003938_abnormal_ear_development0.55881573
132MP0009053_abnormal_anal_canal0.54526391
133MP0006035_abnormal_mitochondrial_morpho0.53463989
134MP0005266_abnormal_metabolism0.51886048
135MP0002092_abnormal_eye_morphology0.50767391
136MP0008789_abnormal_olfactory_epithelium0.50516516
137MP0002075_abnormal_coat/hair_pigmentati0.50149375
138MP0000716_abnormal_immune_system0.47307014
139MP0004264_abnormal_extraembryonic_tissu0.47022055
140MP0003448_altered_tumor_morphology0.46196475
141MP0000750_abnormal_muscle_regeneration0.45073322

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.80119204
2Breast hypoplasia (HP:0003187)5.06045768
3Chromsome breakage (HP:0040012)4.28418763
4Chromosomal breakage induced by crosslinking agents (HP:0003221)4.11223455
5Patellar aplasia (HP:0006443)3.93953020
6Abnormality of cells of the erythroid lineage (HP:0012130)3.79752972
7Aplasia/Hypoplasia of the patella (HP:0006498)3.70242796
8Reticulocytopenia (HP:0001896)3.67739207
9Ependymoma (HP:0002888)3.66321076
10Abnormal number of erythroid precursors (HP:0012131)3.61838890
11Carpal bone hypoplasia (HP:0001498)3.56909452
12Medulloblastoma (HP:0002885)3.51017612
13Oral leukoplakia (HP:0002745)3.45363836
14Colon cancer (HP:0003003)3.43839470
15Selective tooth agenesis (HP:0001592)3.43705188
16Abnormality of chromosome stability (HP:0003220)3.43562325
17Meckel diverticulum (HP:0002245)3.41150127
18Acute necrotizing encephalopathy (HP:0006965)3.39713016
19Impulsivity (HP:0100710)3.37792832
20Abnormality of the ileum (HP:0001549)3.29868996
21Abnormality of the preputium (HP:0100587)3.28711785
22Acute encephalopathy (HP:0006846)3.23646193
23Rhabdomyosarcoma (HP:0002859)3.19095107
24Absent radius (HP:0003974)3.16052267
25Abnormal mitochondria in muscle tissue (HP:0008316)3.13094577
26Premature ovarian failure (HP:0008209)3.10282285
27Aplasia/Hypoplasia of the uvula (HP:0010293)3.09737465
28Increased CSF lactate (HP:0002490)3.07514774
29Abnormality of the labia minora (HP:0012880)3.06935609
30Aplastic anemia (HP:0001915)3.06352724
31Agnosia (HP:0010524)3.01511509
32Rough bone trabeculation (HP:0100670)3.00961824
33Mitochondrial inheritance (HP:0001427)2.98167835
34Increased hepatocellular lipid droplets (HP:0006565)2.97325953
35Absent forearm bone (HP:0003953)2.95798790
36Aplasia involving forearm bones (HP:0009822)2.95798790
37Duodenal stenosis (HP:0100867)2.95328984
38Small intestinal stenosis (HP:0012848)2.95328984
39Cerebral hypomyelination (HP:0006808)2.90845025
40Absent thumb (HP:0009777)2.85671198
41Myelodysplasia (HP:0002863)2.84002369
42Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.79708716
43Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.78686527
44Abnormality of alanine metabolism (HP:0010916)2.78686527
45Hyperalaninemia (HP:0003348)2.78686527
46Lipid accumulation in hepatocytes (HP:0006561)2.78246693
47Progressive macrocephaly (HP:0004481)2.73663614
48Degeneration of anterior horn cells (HP:0002398)2.70231658
49Abnormality of the anterior horn cell (HP:0006802)2.70231658
50Increased serum lactate (HP:0002151)2.64057153
51Secondary amenorrhea (HP:0000869)2.63057928
52Bone marrow hypocellularity (HP:0005528)2.60324282
53Facial hemangioma (HP:0000329)2.55822546
54Hepatocellular necrosis (HP:0001404)2.55250915
55Supernumerary spleens (HP:0009799)2.52044273
56Macrocytic anemia (HP:0001972)2.50800476
57Cerebral edema (HP:0002181)2.47719881
58Microretrognathia (HP:0000308)2.46812058
59Sloping forehead (HP:0000340)2.46411934
60Hypoplasia of the capital femoral epiphysis (HP:0003090)2.44729058
61Neoplasm of the pancreas (HP:0002894)2.41667406
62Abnormality of the duodenum (HP:0002246)2.40861071
63Neoplasm of striated muscle (HP:0009728)2.37825864
64Increased nuchal translucency (HP:0010880)2.37435767
65Abnormal lung lobation (HP:0002101)2.36628570
66Premature graying of hair (HP:0002216)2.34262609
67Pallor (HP:0000980)2.33816897
683-Methylglutaconic aciduria (HP:0003535)2.33113038
69Hypoplasia of the pons (HP:0012110)2.32934739
70Tracheoesophageal fistula (HP:0002575)2.32773376
71Abnormality of the pons (HP:0007361)2.32489775
72Abnormality of the astrocytes (HP:0100707)2.32042499
73Astrocytoma (HP:0009592)2.32042499
74Abnormality of the carotid arteries (HP:0005344)2.29764573
75Hepatic necrosis (HP:0002605)2.29658577
76Basal cell carcinoma (HP:0002671)2.29211015
77Microvesicular hepatic steatosis (HP:0001414)2.25811748
78Cafe-au-lait spot (HP:0000957)2.25556826
79Pancreatic fibrosis (HP:0100732)2.24922496
80Lactic acidosis (HP:0003128)2.24703128
81Horseshoe kidney (HP:0000085)2.24563869
82Multiple enchondromatosis (HP:0005701)2.24300996
83Pancreatic cysts (HP:0001737)2.23621510
84Short thumb (HP:0009778)2.23354765
85Atresia of the external auditory canal (HP:0000413)2.23258863
86Ectopic kidney (HP:0000086)2.19618756
87Aplasia/Hypoplasia of the sternum (HP:0006714)2.17278511
88Renal Fanconi syndrome (HP:0001994)2.14559002
89Neoplasm of the oral cavity (HP:0100649)2.14301770
90Abnormality of DNA repair (HP:0003254)2.13894780
91Abnormal trabecular bone morphology (HP:0100671)2.12181752
92Abnormality of the renal collecting system (HP:0004742)2.10579064
93High pitched voice (HP:0001620)2.10523835
94Cellular immunodeficiency (HP:0005374)2.09263867
95Glioma (HP:0009733)2.08367515
96Abnormal number of incisors (HP:0011064)2.08037709
97Triphalangeal thumb (HP:0001199)2.07829956
98Type I transferrin isoform profile (HP:0003642)2.06150102
99Prominent nose (HP:0000448)2.05637624
100Slender long bone (HP:0003100)2.05580514
101Trismus (HP:0000211)2.04185692
102Nephroblastoma (Wilms tumor) (HP:0002667)2.03431900
103Abnormality of cochlea (HP:0000375)2.01462187
104Increased intramyocellular lipid droplets (HP:0012240)2.01354564
105Overlapping toe (HP:0001845)2.01035101
106Proximal placement of thumb (HP:0009623)1.99348011
10711 pairs of ribs (HP:0000878)1.99038803
108Abnormality of serum amino acid levels (HP:0003112)1.98285230
109Molar tooth sign on MRI (HP:0002419)1.97759744
110Abnormality of midbrain morphology (HP:0002418)1.97759744
111Aplasia/hypoplasia of the humerus (HP:0006507)1.96824256
112Pancytopenia (HP:0001876)1.96774367
113Aplasia/Hypoplasia of the sacrum (HP:0008517)1.96340989
114Pendular nystagmus (HP:0012043)1.95643821
115Hyperglycinemia (HP:0002154)1.95263517
116Squamous cell carcinoma (HP:0002860)1.94127383
117Duplicated collecting system (HP:0000081)1.92837043
118Aplasia/Hypoplasia of the breasts (HP:0010311)1.92471621
119Abnormality of the heme biosynthetic pathway (HP:0010472)1.91999320
120Cleft eyelid (HP:0000625)1.91690880
121Decreased activity of mitochondrial respiratory chain (HP:0008972)1.91185548
122Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.91185548
123Deviation of the thumb (HP:0009603)1.90627823
124Embryonal renal neoplasm (HP:0011794)1.89052741
125Clubbing of toes (HP:0100760)1.88009776
126Breast aplasia (HP:0100783)1.87340242
127Hypoplasia of the radius (HP:0002984)1.86730987
128Progressive muscle weakness (HP:0003323)1.86407913
129Abnormal protein N-linked glycosylation (HP:0012347)1.85785608
130Abnormal protein glycosylation (HP:0012346)1.85785608
131Abnormal glycosylation (HP:0012345)1.85785608
132Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.85785608
133Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.85373311
134Abnormal spermatogenesis (HP:0008669)1.85164305
135Bilateral microphthalmos (HP:0007633)1.84164618
136Rib fusion (HP:0000902)1.83298476
137Abnormality of reticulocytes (HP:0004312)1.83139235
138Neoplasm of the colon (HP:0100273)1.82202658
139Megaloblastic anemia (HP:0001889)1.81996452
140Increased serum pyruvate (HP:0003542)1.81387223
141Shawl scrotum (HP:0000049)1.81246893
142CNS hypomyelination (HP:0003429)1.80678373
143Missing ribs (HP:0000921)1.80441169
144Abnormality of glycolysis (HP:0004366)1.79233702
145Absent epiphyses (HP:0010577)1.78445327
146Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.78445327
147Hyperglycinuria (HP:0003108)1.77353478
148True hermaphroditism (HP:0010459)1.76756086
149Abnormality of homocysteine metabolism (HP:0010919)1.75520412
150Homocystinuria (HP:0002156)1.75520412
151Methylmalonic acidemia (HP:0002912)1.75500561
152Sclerocornea (HP:0000647)1.73916399
153Preaxial hand polydactyly (HP:0001177)1.72585383
154Exercise intolerance (HP:0003546)1.72134903
155Optic disc pallor (HP:0000543)1.71957411
156Aplasia/Hypoplasia of the fovea (HP:0008060)1.70943678
157Hypoplasia of the fovea (HP:0007750)1.70943678
158Respiratory difficulties (HP:0002880)1.70670374
159Lethargy (HP:0001254)1.68965652

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.95341039
2BUB14.80118668
3WEE14.47192439
4VRK23.14093576
5NEK23.11184208
6TTK3.07178870
7PLK42.89532157
8EIF2AK12.53474280
9PBK2.48982002
10NEK12.48841109
11CDK192.44786136
12ACVR1B2.35703852
13PLK12.28796583
14NUAK12.26935935
15SRPK12.13881803
16BRSK22.11969259
17TAF12.00699940
18CDK71.83692356
19MAP3K101.80387946
20TESK21.80302563
21CHEK21.78740032
22EEF2K1.77782255
23AURKB1.76541674
24CDK121.75440338
25TSSK61.72927127
26STK101.70394325
27VRK11.68499900
28MST41.67463704
29NME21.64403734
30TLK11.62071563
31BRSK11.56498849
32CDK41.56237312
33ATR1.56175836
34MAP3K81.55182638
35NME11.54371201
36RPS6KB21.50538976
37AURKA1.47716597
38PLK31.46670468
39DYRK31.41139844
40BMPR1B1.40855733
41EIF2AK31.36423161
42TRIM281.34575999
43STK41.33542621
44STK161.30812808
45MKNK11.28600403
46CHEK11.28093105
47EPHA21.18842033
48CCNB11.15671815
49SCYL21.15522812
50RPS6KA41.15316122
51PASK1.14810741
52BCKDK1.08622336
53BRAF1.04479338
54WNK41.03986245
55MKNK21.01068989
56CDK20.92159250
57ATM0.89727698
58LATS20.89266067
59PDK20.88911759
60MELK0.88563847
61TNIK0.84854561
62PAK40.84478309
63PIM10.83097686
64WNK30.81204289
65LRRK20.79686464
66MAPKAPK30.79036403
67STK30.75959694
68CDK80.75147800
69PAK10.73388132
70MAP4K20.72700907
71FRK0.72144505
72PLK20.70281963
73MAPKAPK50.70005399
74TGFBR10.69111812
75CDK10.68106099
76CDK60.67594537
77ALK0.61572780
78PNCK0.59273509
79CSNK2A20.58874741
80CSNK1G10.57982990
81CSNK2A10.57291831
82CSNK1G30.54707415
83BCR0.54207309
84GRK10.53906400
85ADRBK20.53087013
86MAP3K90.52392763
87KDR0.52092795
88MAP3K60.51995384
89PRKCI0.51617616
90MAP3K40.50193291
91PIM20.49195792
92MAP4K10.48357421
93MAP3K110.47444910
94MAP2K30.46361154
95ZAK0.45821936
96BRD40.45451351
97OXSR10.45290246
98STK390.44349440
99RAF10.43896068
100INSRR0.43594056
101STK38L0.41863509
102FLT30.41588828
103CSNK1G20.40573516
104MTOR0.39222544
105EIF2AK20.37767837
106PKN20.37021883
107MUSK0.36132685
108CDK11A0.35466491
109PINK10.35207057
110CSNK1E0.34767416
111TXK0.34637999
112CSNK1A1L0.33963751
113CLK10.33805297
114MOS0.32552865
115PDK40.32502081
116PDK30.32502081
117MAP2K70.32224871
118AKT20.32128160
119DYRK20.32093464
120RPS6KA50.31344897
121MAP3K120.31200435
122TESK10.30704855
123PRKDC0.29638606
124MAPK110.29637178
125LATS10.27905179
126ABL20.26133879
127SMG10.23627084
128PRKCG0.22766846
129MAPK140.22641790
130ERBB40.21449935
131GRK60.21082193
132CSNK1D0.20309425
133DAPK10.17848220
134AKT30.17159193
135CDK150.17133240
136ILK0.16998257

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.53640110
2Mismatch repair_Homo sapiens_hsa034304.74699184
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.72987531
4Homologous recombination_Homo sapiens_hsa034403.44206582
5Base excision repair_Homo sapiens_hsa034103.31695657
6RNA transport_Homo sapiens_hsa030133.22685327
7Spliceosome_Homo sapiens_hsa030403.20448619
8Cell cycle_Homo sapiens_hsa041103.15734108
9RNA polymerase_Homo sapiens_hsa030203.09222567
10Nucleotide excision repair_Homo sapiens_hsa034202.99660451
11Ribosome_Homo sapiens_hsa030102.98543131
12Proteasome_Homo sapiens_hsa030502.80711512
13One carbon pool by folate_Homo sapiens_hsa006702.54750845
14Pyrimidine metabolism_Homo sapiens_hsa002402.52434372
15Fanconi anemia pathway_Homo sapiens_hsa034602.47928868
16Oxidative phosphorylation_Homo sapiens_hsa001902.29904110
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.12570650
18Parkinsons disease_Homo sapiens_hsa050122.11050500
19Basal transcription factors_Homo sapiens_hsa030222.05630040
20RNA degradation_Homo sapiens_hsa030182.02083922
21Non-homologous end-joining_Homo sapiens_hsa034501.99934813
22p53 signaling pathway_Homo sapiens_hsa041151.76094633
23mRNA surveillance pathway_Homo sapiens_hsa030151.70208622
24Vitamin B6 metabolism_Homo sapiens_hsa007501.35277821
25Propanoate metabolism_Homo sapiens_hsa006401.32180425
26Purine metabolism_Homo sapiens_hsa002301.31446838
27Oocyte meiosis_Homo sapiens_hsa041141.25769645
28Systemic lupus erythematosus_Homo sapiens_hsa053221.24876733
29Alzheimers disease_Homo sapiens_hsa050101.19097407
30Folate biosynthesis_Homo sapiens_hsa007901.12706968
31Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.11141009
32Pyruvate metabolism_Homo sapiens_hsa006201.10564520
33Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.09904783
34Epstein-Barr virus infection_Homo sapiens_hsa051691.06854689
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.05336398
36Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.03750030
37Steroid biosynthesis_Homo sapiens_hsa001001.01531412
38Biosynthesis of amino acids_Homo sapiens_hsa012300.99563237
39Pentose phosphate pathway_Homo sapiens_hsa000300.99507772
40Fatty acid elongation_Homo sapiens_hsa000620.97735614
41Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.94243272
42Viral carcinogenesis_Homo sapiens_hsa052030.92541420
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.88401845
44Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.81459708
45Sulfur relay system_Homo sapiens_hsa041220.79375605
46Herpes simplex infection_Homo sapiens_hsa051680.78703147
47Selenocompound metabolism_Homo sapiens_hsa004500.75459624
48Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.75195211
49Butanoate metabolism_Homo sapiens_hsa006500.75190497
50Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.74250016
51Drug metabolism - other enzymes_Homo sapiens_hsa009830.72190453
52Phototransduction_Homo sapiens_hsa047440.70643081
53Antigen processing and presentation_Homo sapiens_hsa046120.69341844
54HTLV-I infection_Homo sapiens_hsa051660.68707493
55Cardiac muscle contraction_Homo sapiens_hsa042600.65321370
56Cyanoamino acid metabolism_Homo sapiens_hsa004600.64065507
57MicroRNAs in cancer_Homo sapiens_hsa052060.63853984
58Olfactory transduction_Homo sapiens_hsa047400.63336194
59Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.55795730
60Maturity onset diabetes of the young_Homo sapiens_hsa049500.55452889
61Glutathione metabolism_Homo sapiens_hsa004800.54728336
62Small cell lung cancer_Homo sapiens_hsa052220.54398524
63Renin-angiotensin system_Homo sapiens_hsa046140.54072840
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52927219
65Sulfur metabolism_Homo sapiens_hsa009200.51539868
66Nitrogen metabolism_Homo sapiens_hsa009100.49928310
67Thyroid cancer_Homo sapiens_hsa052160.46456819
682-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.45266057
69Carbon metabolism_Homo sapiens_hsa012000.44779359
70Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.44504586
71Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.43125437
72Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.41909778
73Peroxisome_Homo sapiens_hsa041460.40741609
74Colorectal cancer_Homo sapiens_hsa052100.39753901
75Transcriptional misregulation in cancer_Homo sapiens_hsa052020.38617307
76Alcoholism_Homo sapiens_hsa050340.38258390
77Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.36291840
78Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.36019570
79TGF-beta signaling pathway_Homo sapiens_hsa043500.35385625
80Huntingtons disease_Homo sapiens_hsa050160.35358655
81Apoptosis_Homo sapiens_hsa042100.34218555
82Hippo signaling pathway_Homo sapiens_hsa043900.32773639
83Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.31008291
84Bladder cancer_Homo sapiens_hsa052190.29590119
85Fructose and mannose metabolism_Homo sapiens_hsa000510.29163517
86Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.29005158
87Legionellosis_Homo sapiens_hsa051340.28868385
88Caffeine metabolism_Homo sapiens_hsa002320.28520259
89Fatty acid metabolism_Homo sapiens_hsa012120.27773970
90Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.27211034
91Shigellosis_Homo sapiens_hsa051310.26983830
92Hepatitis B_Homo sapiens_hsa051610.25530414
93Tryptophan metabolism_Homo sapiens_hsa003800.25215318
94Notch signaling pathway_Homo sapiens_hsa043300.23139183
95mTOR signaling pathway_Homo sapiens_hsa041500.22515934
96Ether lipid metabolism_Homo sapiens_hsa005650.21901966
97N-Glycan biosynthesis_Homo sapiens_hsa005100.21763809
98Chronic myeloid leukemia_Homo sapiens_hsa052200.21755326
99Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.20827893
100Vitamin digestion and absorption_Homo sapiens_hsa049770.20606131
101alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.20265910
102Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.19384074
103Metabolic pathways_Homo sapiens_hsa011000.18687215
104Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.18196132
105Primary immunodeficiency_Homo sapiens_hsa053400.16788803
106Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.16039400
107Collecting duct acid secretion_Homo sapiens_hsa049660.15881669
108Protein export_Homo sapiens_hsa030600.15815415
109HIF-1 signaling pathway_Homo sapiens_hsa040660.15656159
110Basal cell carcinoma_Homo sapiens_hsa052170.15334834
111Pathways in cancer_Homo sapiens_hsa052000.13968011
112Pancreatic cancer_Homo sapiens_hsa052120.13738103
113Central carbon metabolism in cancer_Homo sapiens_hsa052300.13732952
114Arginine biosynthesis_Homo sapiens_hsa002200.13683055
115Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.13662039
116Arginine and proline metabolism_Homo sapiens_hsa003300.13088877
117Pentose and glucuronate interconversions_Homo sapiens_hsa000400.12942650
118Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.12499492
119Galactose metabolism_Homo sapiens_hsa000520.12374879
120Nicotine addiction_Homo sapiens_hsa050330.12322965
121beta-Alanine metabolism_Homo sapiens_hsa004100.11993743
122Retinol metabolism_Homo sapiens_hsa008300.11092272
123Linoleic acid metabolism_Homo sapiens_hsa005910.10663019
124Hedgehog signaling pathway_Homo sapiens_hsa043400.09672782
125Measles_Homo sapiens_hsa051620.07957595
126Influenza A_Homo sapiens_hsa051640.07919626
127Non-small cell lung cancer_Homo sapiens_hsa052230.07209866
128FoxO signaling pathway_Homo sapiens_hsa040680.06237893
129Prostate cancer_Homo sapiens_hsa052150.06144961
130Adherens junction_Homo sapiens_hsa045200.05684110
131Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.05608564
132Lysine degradation_Homo sapiens_hsa003100.04922807
133NOD-like receptor signaling pathway_Homo sapiens_hsa046210.04348378
134Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.04071597
135Regulation of autophagy_Homo sapiens_hsa041400.04002547
136Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.02869550

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