AURKAIP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)7.09849969
2ATP synthesis coupled proton transport (GO:0015986)6.51208881
3energy coupled proton transport, down electrochemical gradient (GO:0015985)6.51208881
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.86810677
5respiratory electron transport chain (GO:0022904)5.52336366
6electron transport chain (GO:0022900)5.38523294
7proteasome assembly (GO:0043248)5.28344771
8ribosomal small subunit assembly (GO:0000028)5.23036555
9ribosomal small subunit biogenesis (GO:0042274)5.06771362
10viral transcription (GO:0019083)5.06307697
11translational termination (GO:0006415)4.91339180
12DNA deamination (GO:0045006)4.81910871
13protein maturation by protein folding (GO:0022417)4.76759033
14cotranslational protein targeting to membrane (GO:0006613)4.66536509
15SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.65688650
16establishment of protein localization to mitochondrial membrane (GO:0090151)4.64712337
17protein targeting to ER (GO:0045047)4.59543363
18GDP-mannose metabolic process (GO:0019673)4.58975619
19chaperone-mediated protein transport (GO:0072321)4.57538531
20translational elongation (GO:0006414)4.44286005
21protein localization to endoplasmic reticulum (GO:0070972)4.43481570
22protein complex biogenesis (GO:0070271)4.42801916
23regulation of mitochondrial translation (GO:0070129)4.42230205
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.41495579
25mitochondrial respiratory chain complex I assembly (GO:0032981)4.41495579
26NADH dehydrogenase complex assembly (GO:0010257)4.41495579
27oxidative phosphorylation (GO:0006119)4.40194552
28establishment of protein localization to endoplasmic reticulum (GO:0072599)4.36321888
29maturation of SSU-rRNA (GO:0030490)4.28349761
30pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.20501386
31regulation of cellular amino acid metabolic process (GO:0006521)4.17621095
32mitochondrial respiratory chain complex assembly (GO:0033108)4.17027011
33ribosomal large subunit biogenesis (GO:0042273)4.13823122
34negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.13174185
35translation (GO:0006412)4.11856473
36negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.11416983
37transcription elongation from RNA polymerase III promoter (GO:0006385)4.06379229
38termination of RNA polymerase III transcription (GO:0006386)4.06379229
39protein neddylation (GO:0045116)4.03937870
40translational initiation (GO:0006413)3.95330066
41viral life cycle (GO:0019058)3.94908549
42protein targeting to mitochondrion (GO:0006626)3.94321667
43establishment of protein localization to mitochondrion (GO:0072655)3.94072985
44cellular protein complex disassembly (GO:0043624)3.92970179
45GTP biosynthetic process (GO:0006183)3.86644359
46DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.85467836
47negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.84654078
48negative regulation of ligase activity (GO:0051352)3.84654078
49cullin deneddylation (GO:0010388)3.84369499
50nucleobase-containing small molecule interconversion (GO:0015949)3.83740043
51antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.80897754
52L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.80791035
53pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.77920602
542-deoxyribonucleotide biosynthetic process (GO:0009265)3.77353338
55deoxyribose phosphate biosynthetic process (GO:0046385)3.77353338
56intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.77194968
57signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.77194968
58positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.76593638
59signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.72257779
60signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.72257779
61signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.72257779
62protein deneddylation (GO:0000338)3.68125558
63signal transduction involved in DNA integrity checkpoint (GO:0072401)3.65465745
64signal transduction involved in DNA damage checkpoint (GO:0072422)3.65465745
65protein localization to mitochondrion (GO:0070585)3.64984339
66regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.63239301
67NADH metabolic process (GO:0006734)3.61133703
68purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.60397424
69nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.60062043
70signal transduction involved in cell cycle checkpoint (GO:0072395)3.59296362
71purine nucleoside triphosphate biosynthetic process (GO:0009145)3.58563085
72cellular component biogenesis (GO:0044085)3.54906282
73antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.54882481
74pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.53986554
75ATP biosynthetic process (GO:0006754)3.52898299
76formation of translation preinitiation complex (GO:0001731)3.51272354
77aldehyde catabolic process (GO:0046185)3.50587108
78UTP biosynthetic process (GO:0006228)3.49790856
79anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.49602235
80guanosine-containing compound biosynthetic process (GO:1901070)3.48220000
81ribonucleoprotein complex biogenesis (GO:0022613)3.47192168
82pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.46320860
83deoxyribonucleotide catabolic process (GO:0009264)3.45321950
84peptidyl-arginine omega-N-methylation (GO:0035247)3.42512597
85nucleotide salvage (GO:0043173)3.42262217
867-methylguanosine mRNA capping (GO:0006370)3.41656326
87respiratory chain complex IV assembly (GO:0008535)3.39916867
88metallo-sulfur cluster assembly (GO:0031163)3.37461977
89iron-sulfur cluster assembly (GO:0016226)3.37461977
90inner mitochondrial membrane organization (GO:0007007)3.36848673
91pyrimidine nucleotide catabolic process (GO:0006244)3.36078784
92deoxyribose phosphate catabolic process (GO:0046386)3.35919428
93ribonucleoside triphosphate biosynthetic process (GO:0009201)3.34352728
94L-methionine salvage (GO:0071267)3.32396941
95L-methionine biosynthetic process (GO:0071265)3.32396941
96amino acid salvage (GO:0043102)3.32396941
97RNA capping (GO:0036260)3.31254302
987-methylguanosine RNA capping (GO:0009452)3.31254302
99positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.26955340
100protein complex disassembly (GO:0043241)3.26601090
101regulation of cellular amine metabolic process (GO:0033238)3.25348692
102nuclear envelope reassembly (GO:0031468)3.25090798
103mitotic nuclear envelope reassembly (GO:0007084)3.25090798
104deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.24742143
105mitochondrial transport (GO:0006839)3.22244966
106hydrogen ion transmembrane transport (GO:1902600)3.21681834
107base-excision repair, AP site formation (GO:0006285)3.21250043
108regulation of cellular respiration (GO:0043457)3.20986920
109UTP metabolic process (GO:0046051)3.20008076
110positive regulation of ligase activity (GO:0051351)3.19563016
111proline biosynthetic process (GO:0006561)3.19062036
112pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.18244887
113DNA strand elongation involved in DNA replication (GO:0006271)3.15649400
114macromolecular complex disassembly (GO:0032984)3.15168957
115rRNA modification (GO:0000154)3.15122475
116purine deoxyribonucleotide catabolic process (GO:0009155)3.14512024
117CTP biosynthetic process (GO:0006241)3.13210007
118CTP metabolic process (GO:0046036)3.13210007
119negative regulation of release of cytochrome c from mitochondria (GO:0090201)3.12515923
120cytochrome complex assembly (GO:0017004)3.09883216
121DNA strand elongation (GO:0022616)3.08968459
122pentose metabolic process (GO:0019321)3.07830399
123deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.07615753
124histone arginine methylation (GO:0034969)3.07518456
125pseudouridine synthesis (GO:0001522)3.07052929
126protein targeting to membrane (GO:0006612)3.05547050
1272-deoxyribonucleotide metabolic process (GO:0009394)3.04537455
128establishment of viral latency (GO:0019043)3.03665483
129telomere maintenance via semi-conservative replication (GO:0032201)3.03550044
130establishment of integrated proviral latency (GO:0075713)3.02487803
131ribosome biogenesis (GO:0042254)3.02140707
132nucleoside triphosphate biosynthetic process (GO:0009142)3.01500981
133nucleoside salvage (GO:0043174)3.00987344
134aerobic respiration (GO:0009060)3.00126805
135rRNA processing (GO:0006364)2.99176302
136purine nucleotide salvage (GO:0032261)2.98680917
137transcription from mitochondrial promoter (GO:0006390)2.98488801

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.66050954
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.20297960
3* JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.15270522
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.14128263
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.10212481
6EST1_17652178_ChIP-ChIP_JURKAT_Human4.03388113
7MYC_18555785_ChIP-Seq_MESCs_Mouse3.97632853
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.91388217
9* ETS1_20019798_ChIP-Seq_JURKAT_Human3.71800707
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.50533528
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.41962580
12MYC_18358816_ChIP-ChIP_MESCs_Mouse3.13977039
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.10719783
14CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.96834977
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.81651512
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.65811850
17MYC_19030024_ChIP-ChIP_MESCs_Mouse2.64336520
18MYC_19079543_ChIP-ChIP_MESCs_Mouse2.55830199
19THAP11_20581084_ChIP-Seq_MESCs_Mouse2.50520862
20* VDR_23849224_ChIP-Seq_CD4+_Human2.50483492
21ELF1_17652178_ChIP-ChIP_JURKAT_Human2.49657318
22PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.49431755
23SRF_21415370_ChIP-Seq_HL-1_Mouse2.46632543
24YY1_21170310_ChIP-Seq_MESCs_Mouse2.42647016
25DCP1A_22483619_ChIP-Seq_HELA_Human2.40788734
26E2F1_18555785_ChIP-Seq_MESCs_Mouse2.37845992
27XRN2_22483619_ChIP-Seq_HELA_Human2.35413050
28E2F7_22180533_ChIP-Seq_HELA_Human2.22168038
29* FOXP3_21729870_ChIP-Seq_TREG_Human2.14650820
30VDR_21846776_ChIP-Seq_THP-1_Human2.08719208
31TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.05914315
32* GABP_19822575_ChIP-Seq_HepG2_Human2.01555893
33ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.96684483
34* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.88537833
35ZNF263_19887448_ChIP-Seq_K562_Human1.87640965
36LXR_22292898_ChIP-Seq_THP-1_Human1.85036065
37* TTF2_22483619_ChIP-Seq_HELA_Human1.83544258
38CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.83475541
39CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.80351021
40* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.79019596
41PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.76205476
42TET1_21451524_ChIP-Seq_MESCs_Mouse1.72742903
43SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.68811718
44ELK1_19687146_ChIP-ChIP_HELA_Human1.66386746
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.64109823
46* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.63662242
47HOXB4_20404135_ChIP-ChIP_EML_Mouse1.59329847
48POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.55853328
49MYC_22102868_ChIP-Seq_BL_Human1.53447572
50BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.50223131
51CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.49562835
52TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.48489498
53ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.46266894
54* ELK3_25401928_ChIP-Seq_HUVEC_Human1.45168015
55NANOG_18555785_ChIP-Seq_MESCs_Mouse1.44595284
56* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.44488284
57RARG_19884340_ChIP-ChIP_MEFs_Mouse1.43357972
58ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.42548768
59E2F4_17652178_ChIP-ChIP_JURKAT_Human1.41935552
60FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.41488910
61P68_20966046_ChIP-Seq_HELA_Human1.41443226
62PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.39925572
63* RACK7_27058665_Chip-Seq_MCF-7_Human1.37733489
64ELK1_22589737_ChIP-Seq_MCF10A_Human1.35389731
65ERG_20887958_ChIP-Seq_HPC-7_Mouse1.34636446
66ZFX_18555785_ChIP-Seq_MESCs_Mouse1.34122068
67SRY_22984422_ChIP-ChIP_TESTIS_Rat1.33122719
68TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.32894714
69* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.31720948
70POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.29525867
71* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.29049906
72* ELF1_20517297_ChIP-Seq_JURKAT_Human1.28864901
73MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.28250422
74HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.25146371
75CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.23871962
76* SA1_27219007_Chip-Seq_ERYTHROID_Human1.23343691
77BCL6_27268052_Chip-Seq_Bcells_Human1.22602427
78MYC_18940864_ChIP-ChIP_HL60_Human1.21104488
79YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.19410157
80CTCF_26484167_Chip-Seq_Bcells_Mouse1.18362299
81THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.17844728
82CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.17224667
83* CTCF_18555785_ChIP-Seq_MESCs_Mouse1.15805923
84ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.14980041
85FOXM1_23109430_ChIP-Seq_U2OS_Human1.14811802
86BCOR_27268052_Chip-Seq_Bcells_Human1.13727651
87BP1_19119308_ChIP-ChIP_Hs578T_Human1.12529414
88POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.11834894
89SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.10837426
90STAT3_1855785_ChIP-Seq_MESCs_Mouse1.10061799
91CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.09221446
92* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.06830243
93HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.05183260
94PU.1_20513432_ChIP-Seq_Bcells_Mouse1.04822772
95* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.04248129
96* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.04184662
97* KDM5A_27292631_Chip-Seq_BREAST_Human1.03355495
98CIITA_25753668_ChIP-Seq_RAJI_Human1.03351264
99* MAF_26560356_Chip-Seq_TH2_Human1.03340768
100CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.02884729
101* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.01998207
102SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.01884625
103SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.01328260
104SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.01224653
105CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.98821060
106FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.97636145
107OCT4_18692474_ChIP-Seq_MEFs_Mouse0.96429187
108SOX2_18692474_ChIP-Seq_MEFs_Mouse0.95641930
109PADI4_21655091_ChIP-ChIP_MCF-7_Human0.94902177
110KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.93388944
111EGR1_23403033_ChIP-Seq_LIVER_Mouse0.91890423
112YY1_22570637_ChIP-Seq_MALME-3M_Human0.91845973
113CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.89278809
114TFEB_21752829_ChIP-Seq_HELA_Human0.87311752
115TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.86381214
116SOX17_20123909_ChIP-Seq_XEN_Mouse0.85821237
117SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.84969620
118EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.84109239
119STAT1_20625510_ChIP-Seq_HELA_Human0.83748603
120MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.82526483
121NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.82201982
122TBX5_21415370_ChIP-Seq_HL-1_Mouse0.81276726
123IRF1_19129219_ChIP-ChIP_H3396_Human0.80362548
124FOXP1_21924763_ChIP-Seq_HESCs_Human0.79698786
125DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.79134865
126KLF4_18555785_ChIP-Seq_MESCs_Mouse0.78805956
127PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.76959543
128* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.76702233
129KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.75985906
130* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.75175332

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis5.19242317
2MP0006036_abnormal_mitochondrial_physio3.82959843
3MP0009379_abnormal_foot_pigmentation3.61673706
4MP0001529_abnormal_vocalization3.52518585
5MP0003186_abnormal_redox_activity3.33092324
6MP0003693_abnormal_embryo_hatching3.02327598
7MP0006035_abnormal_mitochondrial_morpho2.88688632
8MP0004957_abnormal_blastocyst_morpholog2.83056720
9MP0002139_abnormal_hepatobiliary_system2.70548342
10MP0004858_abnormal_nervous_system2.33463818
11MP0005670_abnormal_white_adipose2.30800014
12MP0001764_abnormal_homeostasis2.22277974
13MP0008057_abnormal_DNA_replication2.16411646
14MP0001905_abnormal_dopamine_level2.13992447
15MP0000678_abnormal_parathyroid_gland2.12376042
16MP0005083_abnormal_biliary_tract2.10362768
17MP0003718_maternal_effect2.05763264
18MP0005360_urolithiasis2.00562538
19MP0004185_abnormal_adipocyte_glucose2.00249200
20MP0004142_abnormal_muscle_tone1.97446274
21MP0008007_abnormal_cellular_replicative1.97078372
22MP0005332_abnormal_amino_acid1.94787280
23MP0004147_increased_porphyrin_level1.94019136
24MP0005085_abnormal_gallbladder_physiolo1.89159963
25MP0008932_abnormal_embryonic_tissue1.87803956
26MP0003656_abnormal_erythrocyte_physiolo1.87769465
27MP0003646_muscle_fatigue1.82328843
28MP0002837_dystrophic_cardiac_calcinosis1.80129851
29MP0003195_calcinosis1.80000627
30MP0004233_abnormal_muscle_weight1.78169183
31MP0008875_abnormal_xenobiotic_pharmacok1.77456847
32MP0002877_abnormal_melanocyte_morpholog1.76883970
33MP0005501_abnormal_skin_physiology1.75050738
34MP0005408_hypopigmentation1.65756838
35MP0005365_abnormal_bile_salt1.63009513
36MP0010030_abnormal_orbit_morphology1.61555644
37MP0005266_abnormal_metabolism1.57557915
38MP0003136_yellow_coat_color1.52391233
39MP0005075_abnormal_melanosome_morpholog1.51048244
40MP0002796_impaired_skin_barrier1.49543871
41MP0008058_abnormal_DNA_repair1.48254023
42MP0006276_abnormal_autonomic_nervous1.48007135
43MP0005636_abnormal_mineral_homeostasis1.47179075
44MP0005451_abnormal_body_composition1.45860078
45MP0003077_abnormal_cell_cycle1.45847937
46MP0000358_abnormal_cell_content/1.44155423
47MP0000751_myopathy1.44041082
48MP0009333_abnormal_splenocyte_physiolog1.42861904
49MP0001986_abnormal_taste_sensitivity1.40341254
50MP0001666_abnormal_nutrient_absorption1.38524600
51MP0003011_delayed_dark_adaptation1.37472302
52MP0000350_abnormal_cell_proliferation1.36427730
53MP0005666_abnormal_adipose_tissue1.36244487
54MP0002132_abnormal_respiratory_system1.36157675
55MP0005584_abnormal_enzyme/coenzyme_acti1.31512840
56MP0000490_abnormal_crypts_of1.28809367
57MP0001727_abnormal_embryo_implantation1.27595737
58MP0010094_abnormal_chromosome_stability1.27392287
59MP0009840_abnormal_foam_cell1.24708809
60MP0005376_homeostasis/metabolism_phenot1.24047072
61MP0009697_abnormal_copulation1.20346913
62MP0003786_premature_aging1.19706880
63MP0003880_abnormal_central_pattern1.19372683
64MP0008260_abnormal_autophagy1.18770432
65MP0009785_altered_susceptibility_to1.18576778
66MP0000759_abnormal_skeletal_muscle1.18311931
67MP0005623_abnormal_meninges_morphology1.15841607
68MP0001661_extended_life_span1.15828077
69MP0005319_abnormal_enzyme/_coenzyme1.13808305
70MP0002736_abnormal_nociception_after1.12842440
71MP0004510_myositis1.11172708
72MP0002249_abnormal_larynx_morphology1.10503538
73MP0002876_abnormal_thyroid_physiology1.10309090
74MP0008872_abnormal_physiological_respon1.08855521
75MP0005058_abnormal_lysosome_morphology1.06852691
76MP0000749_muscle_degeneration1.06738012
77MP0003075_altered_response_to1.05745773
78MP0009278_abnormal_bone_marrow1.04720613
79MP0002019_abnormal_tumor_incidence1.04298925
80MP0003111_abnormal_nucleus_morphology1.02468570
81MP0005375_adipose_tissue_phenotype1.01972582
82MP0003191_abnormal_cellular_cholesterol1.01712482
83MP0002080_prenatal_lethality1.01615313
84MP0002332_abnormal_exercise_endurance1.00806007
85MP0003123_paternal_imprinting0.99907506
86MP0009643_abnormal_urine_homeostasis0.98980694
87MP0000681_abnormal_thyroid_gland0.97077469
88MP0008469_abnormal_protein_level0.96778592
89MP0001881_abnormal_mammary_gland0.94698570
90MP0006082_CNS_inflammation0.93896256
91MP0005084_abnormal_gallbladder_morpholo0.92726388
92MP0005330_cardiomyopathy0.91360144
93MP0003453_abnormal_keratinocyte_physiol0.91102678
94MP0000372_irregular_coat_pigmentation0.87293643
95MP0003705_abnormal_hypodermis_morpholog0.87237950
96MP0004145_abnormal_muscle_electrophysio0.87214343
97MP0001542_abnormal_bone_strength0.85783311
98MP0005165_increased_susceptibility_to0.85186068
99MP0000733_abnormal_muscle_development0.84794609
100MP0003436_decreased_susceptibility_to0.82805572
101MP0005410_abnormal_fertilization0.82136746
102MP0003221_abnormal_cardiomyocyte_apopto0.81749837
103MP0001853_heart_inflammation0.80047744
104MP0005166_decreased_susceptibility_to0.79188430
105MP0001873_stomach_inflammation0.79003209
106MP0005025_abnormal_response_to0.78068907
107MP0009672_abnormal_birth_weight0.78035770
108MP0000747_muscle_weakness0.77718848
109MP0001730_embryonic_growth_arrest0.77611341
110MP0000003_abnormal_adipose_tissue0.77586453
111MP0002148_abnormal_hypersensitivity_rea0.77306415
112MP0004043_abnormal_pH_regulation0.77227298
113MP0000750_abnormal_muscle_regeneration0.74725168
114MP0002751_abnormal_autonomic_nervous0.74508713
115MP0002638_abnormal_pupillary_reflex0.74475964
116MP0003724_increased_susceptibility_to0.74234770
117MP0008873_increased_physiological_sensi0.73767491
118MP0004087_abnormal_muscle_fiber0.72736999
119MP0009053_abnormal_anal_canal0.72088874
120MP0004381_abnormal_hair_follicle0.71428730
121MP0002163_abnormal_gland_morphology0.70367756
122MP0005671_abnormal_response_to0.70087018
123MP0000537_abnormal_urethra_morphology0.69705757
124MP0003329_amyloid_beta_deposits0.69643814
125MP0001346_abnormal_lacrimal_gland0.68857297
126MP0002118_abnormal_lipid_homeostasis0.68511724
127MP0000920_abnormal_myelination0.68330130
128MP0005535_abnormal_body_temperature0.67628456
129MP0002822_catalepsy0.67314437
130MP0000313_abnormal_cell_death0.67173511
131MP0010307_abnormal_tumor_latency0.66843125
132MP0002429_abnormal_blood_cell0.66818106
133MP0000858_altered_metastatic_potential0.64548044
134MP0000703_abnormal_thymus_morphology0.63957071
135MP0001697_abnormal_embryo_size0.63657125
136MP0004019_abnormal_vitamin_homeostasis0.62602471
137MP0000689_abnormal_spleen_morphology0.61341240
138MP0002234_abnormal_pharynx_morphology0.60702427
139MP0002722_abnormal_immune_system0.60097582
140MP0005464_abnormal_platelet_physiology0.60011717
141MP0000609_abnormal_liver_physiology0.59454495
142MP0003941_abnormal_skin_development0.59059974
143MP0005384_cellular_phenotype0.58434558
144MP0002269_muscular_atrophy0.58348092
145MP0000343_altered_response_to0.57643478
146MP0010329_abnormal_lipoprotein_level0.56977231
147MP0003315_abnormal_perineum_morphology0.54540325
148MP0009765_abnormal_xenobiotic_induced0.53399383

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.38359301
2Abnormal mitochondria in muscle tissue (HP:0008316)5.98069908
3Mitochondrial inheritance (HP:0001427)5.78258222
4Hepatocellular necrosis (HP:0001404)5.67219406
5Acute encephalopathy (HP:0006846)5.66623740
6Hepatic necrosis (HP:0002605)5.29256396
7Increased CSF lactate (HP:0002490)5.20343726
8Progressive macrocephaly (HP:0004481)5.16851878
9Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.59377622
10Decreased activity of mitochondrial respiratory chain (HP:0008972)4.59377622
11Increased serum pyruvate (HP:0003542)4.45906434
12Abnormality of glycolysis (HP:0004366)4.45906434
13Cerebral edema (HP:0002181)4.35305508
14Increased hepatocellular lipid droplets (HP:0006565)4.26698714
15Abnormality of cells of the erythroid lineage (HP:0012130)4.25376333
163-Methylglutaconic aciduria (HP:0003535)4.17864191
17Lipid accumulation in hepatocytes (HP:0006561)4.06287061
18Abnormal number of erythroid precursors (HP:0012131)4.02553146
19Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.98099097
20Increased serum lactate (HP:0002151)3.96568650
21Lactic acidosis (HP:0003128)3.95153099
22Respiratory failure (HP:0002878)3.88917754
23Renal Fanconi syndrome (HP:0001994)3.72950348
24Increased intramyocellular lipid droplets (HP:0012240)3.71345686
25Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.59065230
26Exercise intolerance (HP:0003546)3.54372240
27Increased muscle lipid content (HP:0009058)3.41894504
28Leukodystrophy (HP:0002415)3.39914945
29Progressive muscle weakness (HP:0003323)3.31423151
30Cerebral hypomyelination (HP:0006808)3.27256807
31CNS demyelination (HP:0007305)3.20621466
32Reticulocytopenia (HP:0001896)3.19386074
33Optic disc pallor (HP:0000543)3.03882400
34Macrocytic anemia (HP:0001972)3.03672398
35Lethargy (HP:0001254)3.00141141
36Testicular atrophy (HP:0000029)2.92061026
37Myopathic facies (HP:0002058)2.87536221
38Exertional dyspnea (HP:0002875)2.82562065
39Emotional lability (HP:0000712)2.76713525
40Microretrognathia (HP:0000308)2.73848953
41Abnormality of aromatic amino acid family metabolism (HP:0004338)2.61299044
42Respiratory difficulties (HP:0002880)2.57462199
43Trismus (HP:0000211)2.52873968
44Microvesicular hepatic steatosis (HP:0001414)2.50699694
45Dicarboxylic aciduria (HP:0003215)2.49046523
46Abnormality of dicarboxylic acid metabolism (HP:0010995)2.49046523
47Glycosuria (HP:0003076)2.48872271
48Abnormality of urine glucose concentration (HP:0011016)2.48872271
49Distal lower limb muscle weakness (HP:0009053)2.48809526
50Hypertensive crisis (HP:0100735)2.48108118
51Centrally nucleated skeletal muscle fibers (HP:0003687)2.42687260
52Neuroendocrine neoplasm (HP:0100634)2.41967656
53Achilles tendon contracture (HP:0001771)2.41690775
54Vertebral compression fractures (HP:0002953)2.41402388
55Pallor (HP:0000980)2.40133337
56Methylmalonic aciduria (HP:0012120)2.39091299
57Hyperthyroidism (HP:0000836)2.38080608
58Abnormality of renal resorption (HP:0011038)2.35655071
59Aplasia/Hypoplasia of the sacrum (HP:0008517)2.32570791
60Hypokinesia (HP:0002375)2.28007679
61Generalized aminoaciduria (HP:0002909)2.25474087
62Reduced antithrombin III activity (HP:0001976)2.25272237
63Abnormality of fatty-acid metabolism (HP:0004359)2.24573644
64Hyperglycinemia (HP:0002154)2.23521136
65Hyperphosphaturia (HP:0003109)2.21187592
66Oral leukoplakia (HP:0002745)2.20755506
67Pheochromocytoma (HP:0002666)2.20489005
68Multiple enchondromatosis (HP:0005701)2.19338412
69Broad distal phalanx of finger (HP:0009836)2.17220489
70Abnormality of the Achilles tendon (HP:0005109)2.16596943
71Truncus arteriosus (HP:0001660)2.16050773
72Vomiting (HP:0002013)2.15303072
73Type I transferrin isoform profile (HP:0003642)2.11211754
74Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.09839051
75Abnormal trabecular bone morphology (HP:0100671)2.09078384
76Gliosis (HP:0002171)2.08620049
77CNS hypomyelination (HP:0003429)2.06641266
78Spastic paraparesis (HP:0002313)2.04084993
79Nausea (HP:0002018)2.00582895
80Fasciculations (HP:0002380)2.00142946
81Prolonged neonatal jaundice (HP:0006579)1.99249473
82Abnormality of alanine metabolism (HP:0010916)1.98130675
83Hyperalaninemia (HP:0003348)1.98130675
84Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.98130675
85Abnormality of the umbilical cord (HP:0010881)1.96994070
86Obstructive lung disease (HP:0006536)1.96528697
87Chronic obstructive pulmonary disease (HP:0006510)1.96528697
88Nemaline bodies (HP:0003798)1.94901443
89Abnormality of glycine metabolism (HP:0010895)1.93658440
90Abnormality of serine family amino acid metabolism (HP:0010894)1.93658440
91Ragged-red muscle fibers (HP:0003200)1.93467858
92Bulbar palsy (HP:0001283)1.92701715
93Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.92064086
94Hyperglycinuria (HP:0003108)1.90765279
95Delusions (HP:0000746)1.90349280
96Muscle fiber inclusion bodies (HP:0100299)1.89655264
97Hyperammonemia (HP:0001987)1.86968115
98Hypobetalipoproteinemia (HP:0003563)1.85272404
99Muscle stiffness (HP:0003552)1.84501695
100Aplastic anemia (HP:0001915)1.83875682
101Axonal loss (HP:0003447)1.83427896
102Abnormality of the heme biosynthetic pathway (HP:0010472)1.83395554
103Abnormality of glycosphingolipid metabolism (HP:0004343)1.81465792
104Abnormality of glycolipid metabolism (HP:0010969)1.81465792
105Abnormality of liposaccharide metabolism (HP:0010968)1.81465792
106Abnormality of the tricuspid valve (HP:0001702)1.81414728
107Stridor (HP:0010307)1.80617326
108Seborrheic dermatitis (HP:0001051)1.80480405
109Esophageal neoplasm (HP:0100751)1.80178482
110Neoplasm of head and neck (HP:0012288)1.80178482
111Opisthotonus (HP:0002179)1.79556866
112Hepatosplenomegaly (HP:0001433)1.78839176
113Abnormality of the anterior horn cell (HP:0006802)1.77889859
114Degeneration of anterior horn cells (HP:0002398)1.77889859
115Abnormal gallbladder physiology (HP:0012438)1.77757504
116Cholecystitis (HP:0001082)1.77757504
117Abnormality of serum amino acid levels (HP:0003112)1.77555830
118Rough bone trabeculation (HP:0100670)1.77251444
119Poor suck (HP:0002033)1.76794714
120Pancytopenia (HP:0001876)1.76408009
121Carpal bone hypoplasia (HP:0001498)1.75587078
122Birth length less than 3rd percentile (HP:0003561)1.75324911
123Petechiae (HP:0000967)1.74926923
124Reduced subcutaneous adipose tissue (HP:0003758)1.74844667
125Blindness (HP:0000618)1.74585211
126Selective tooth agenesis (HP:0001592)1.74442208
127Amniotic constriction ring (HP:0009775)1.74425023
128Abnormality of placental membranes (HP:0011409)1.74425023
129Cerebral palsy (HP:0100021)1.74101115
130Sparse eyelashes (HP:0000653)1.73781235
131Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.71643712
132Abnormal urine phosphate concentration (HP:0012599)1.71301094
133Abnormal protein glycosylation (HP:0012346)1.70950754
134Abnormal glycosylation (HP:0012345)1.70950754
135Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.70950754
136Abnormal protein N-linked glycosylation (HP:0012347)1.70950754
137Postnatal microcephaly (HP:0005484)1.70687258
138Rhabdomyolysis (HP:0003201)1.70028714
139Breast hypoplasia (HP:0003187)1.69228208
140Methylmalonic acidemia (HP:0002912)1.68875747
141Abnormal pupillary function (HP:0007686)1.68804741
142Brushfield spots (HP:0001088)1.68065427
143X-linked dominant inheritance (HP:0001423)1.66677158
144Metabolic acidosis (HP:0001942)1.65781647

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.40735090
2BUB14.09945306
3NME23.90546319
4STK163.77303776
5BCKDK3.28807767
6EIF2AK13.19760117
7TLK13.08963639
8SMG12.87657035
9NME12.83662655
10TESK22.74597738
11MAP3K122.65228562
12WEE12.63075844
13PBK2.30213632
14ARAF2.22314193
15TRIB32.19530399
16MAP3K111.96505836
17SRPK11.93146498
18EIF2AK31.91958854
19CDK191.88246359
20VRK11.87364236
21TSSK61.84808187
22ERN11.84635777
23LIMK11.83398593
24PIM21.81272595
25MST41.77207941
26MYLK1.68449419
27TESK11.66347728
28STK391.65226878
29BRAF1.51466930
30KDR1.39419905
31OXSR11.28710347
32PAK41.20080991
33ABL21.19451148
34AURKA1.19140526
35MAP2K31.10667882
36WNK41.02557807
37IRAK31.02231612
38TTN0.97271022
39PDK20.96206047
40PRPF4B0.96041918
41BLK0.93156735
42DAPK30.91701758
43PRKD30.89401277
44MAP3K30.86206060
45PDK40.84627151
46PDK30.84627151
47PNCK0.84102822
48TAOK10.83418422
49PLK40.83282839
50ILK0.81199493
51CSNK1G30.80784296
52MAP2K60.77266440
53GRK60.77075775
54ADRBK20.76659869
55SIK10.76560992
56CASK0.76388348
57MAP4K10.76010779
58IRAK40.75834910
59CCNB10.75678249
60PLK10.73902658
61ZAP700.73014689
62CSNK2A20.71982347
63CSNK2A10.70520186
64BRSK20.70067368
65DYRK20.69400835
66SCYL20.68191991
67AKT20.67485725
68IRAK20.67135951
69OBSCN0.66481120
70PAK10.65785809
71MAPKAPK50.64638548
72RPS6KB20.63880223
73MAPKAPK30.63177871
74CHEK20.63139072
75ICK0.62315429
76NEK10.60575616
77TAF10.60142673
78IRAK10.59779063
79BCR0.59483922
80CAMK2G0.59108352
81GRK70.57130273
82GRK50.57042379
83AURKB0.56600644
84TXK0.54825753
85DYRK30.54352292
86RPS6KA50.52602754
87PRKCI0.51403799
88MOS0.49870643
89TAOK20.49636017
90PDPK10.48767835
91MAP2K20.48662188
92CDK70.48420077
93MAP3K10.48272901
94EPHA20.48138572
95MAP3K80.47878274
96ATR0.47563973
97CDK40.46280829
98DAPK10.45876576
99CDK11A0.45452680
100ZAK0.44937774
101RPS6KA40.44349792
102ACVR1B0.43509772
103NEK90.42306358
104STK100.42098463
105CDC70.40381354
106PRKG20.40279182
107CAMK2B0.40055708
108LRRK20.39201137
109STK40.36939940
110PIK3CG0.36707026
111BRSK10.36638014
112CSNK1G10.36500947
113CDK150.35939455
114CAMK2D0.35203020
115CDK140.34305872
116CHEK10.34226623
117ADRBK10.34182942
118MST1R0.33833820
119MAP2K70.33810925
120CSNK1A1L0.33564287
121EIF2AK20.32106647
122SYK0.32041702
123MAPK110.31502082
124TYK20.31328803
125TBK10.31231085
126CDK180.30833018
127MUSK0.30625269
128CDK80.30519572
129TTK0.30316138
130PLK30.29952904
131EEF2K0.29925610
132PASK0.29902205
133PHKG10.29547719
134PHKG20.29547719
135LMTK20.29457800
136IKBKB0.28118422
137CDK90.27673807
138RPS6KC10.25091068
139RPS6KL10.25091068

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.61721677
2Ribosome_Homo sapiens_hsa030104.41179708
3Proteasome_Homo sapiens_hsa030504.31219395
4Parkinsons disease_Homo sapiens_hsa050124.02285655
5RNA polymerase_Homo sapiens_hsa030203.04638741
6Huntingtons disease_Homo sapiens_hsa050162.82888272
7Alzheimers disease_Homo sapiens_hsa050102.71075202
8Protein export_Homo sapiens_hsa030602.57393642
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.51404510
10DNA replication_Homo sapiens_hsa030302.20089020
11Pyrimidine metabolism_Homo sapiens_hsa002401.98744959
12Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.82082471
13Mismatch repair_Homo sapiens_hsa034301.77215785
14Folate biosynthesis_Homo sapiens_hsa007901.72628737
15Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.69642114
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.66688376
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.66499503
18Fatty acid elongation_Homo sapiens_hsa000621.64728984
19Sulfur relay system_Homo sapiens_hsa041221.61753010
20Pyruvate metabolism_Homo sapiens_hsa006201.48589786
21Spliceosome_Homo sapiens_hsa030401.46009255
22Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.40013298
23Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.39890113
24Propanoate metabolism_Homo sapiens_hsa006401.39827155
252-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.38433367
26Cardiac muscle contraction_Homo sapiens_hsa042601.36825453
27Nucleotide excision repair_Homo sapiens_hsa034201.35768965
28Carbon metabolism_Homo sapiens_hsa012001.34761388
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.34084156
30Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.34040038
31Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.31627466
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.23954877
33Homologous recombination_Homo sapiens_hsa034401.22321202
34Glutathione metabolism_Homo sapiens_hsa004801.20952987
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.20951813
36Base excision repair_Homo sapiens_hsa034101.20602690
37Vitamin B6 metabolism_Homo sapiens_hsa007501.12368684
38Pentose phosphate pathway_Homo sapiens_hsa000301.12076897
39Collecting duct acid secretion_Homo sapiens_hsa049661.08373432
40Biosynthesis of amino acids_Homo sapiens_hsa012301.08101170
41RNA transport_Homo sapiens_hsa030131.07584799
42Sulfur metabolism_Homo sapiens_hsa009201.04471888
43Peroxisome_Homo sapiens_hsa041461.03961205
44Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.03603913
45Purine metabolism_Homo sapiens_hsa002301.03138167
46Steroid biosynthesis_Homo sapiens_hsa001001.00464149
47Metabolic pathways_Homo sapiens_hsa011001.00421327
48Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.97916851
49One carbon pool by folate_Homo sapiens_hsa006700.96288713
50Cyanoamino acid metabolism_Homo sapiens_hsa004600.92381071
51Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.88598239
52Basal transcription factors_Homo sapiens_hsa030220.84395241
53Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.83733841
54Drug metabolism - other enzymes_Homo sapiens_hsa009830.83708497
55Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82737513
56N-Glycan biosynthesis_Homo sapiens_hsa005100.79597689
57Arginine and proline metabolism_Homo sapiens_hsa003300.79503724
58Phenylalanine metabolism_Homo sapiens_hsa003600.76481294
59Tyrosine metabolism_Homo sapiens_hsa003500.76169241
60Butanoate metabolism_Homo sapiens_hsa006500.76027237
61Fatty acid degradation_Homo sapiens_hsa000710.75484990
62Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.74792498
63Fructose and mannose metabolism_Homo sapiens_hsa000510.67079628
64Vibrio cholerae infection_Homo sapiens_hsa051100.66811333
65Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.65624303
66Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.65293530
67Primary bile acid biosynthesis_Homo sapiens_hsa001200.64932829
68RNA degradation_Homo sapiens_hsa030180.63452510
69Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.63349542
70Pentose and glucuronate interconversions_Homo sapiens_hsa000400.60451990
71beta-Alanine metabolism_Homo sapiens_hsa004100.58518538
72Histidine metabolism_Homo sapiens_hsa003400.57973592
73Bladder cancer_Homo sapiens_hsa052190.57611951
74Fatty acid metabolism_Homo sapiens_hsa012120.56794663
75Arachidonic acid metabolism_Homo sapiens_hsa005900.54661915
76Non-homologous end-joining_Homo sapiens_hsa034500.54427721
77Shigellosis_Homo sapiens_hsa051310.53319738
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.53045644
79Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.50736375
80Chemical carcinogenesis_Homo sapiens_hsa052040.50708034
81Tryptophan metabolism_Homo sapiens_hsa003800.50237495
82Linoleic acid metabolism_Homo sapiens_hsa005910.44633382
83Fat digestion and absorption_Homo sapiens_hsa049750.44591123
84Epstein-Barr virus infection_Homo sapiens_hsa051690.42318272
85Galactose metabolism_Homo sapiens_hsa000520.42002606
86Prion diseases_Homo sapiens_hsa050200.39551949
87SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39344568
88Fanconi anemia pathway_Homo sapiens_hsa034600.38944870
89Selenocompound metabolism_Homo sapiens_hsa004500.38657455
90Primary immunodeficiency_Homo sapiens_hsa053400.37555179
91Systemic lupus erythematosus_Homo sapiens_hsa053220.37483190
92Regulation of autophagy_Homo sapiens_hsa041400.36339443
93Central carbon metabolism in cancer_Homo sapiens_hsa052300.36237481
94Lysosome_Homo sapiens_hsa041420.33757277
95Rheumatoid arthritis_Homo sapiens_hsa053230.32457772
96Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.31680846
97Synaptic vesicle cycle_Homo sapiens_hsa047210.29672607
98Salmonella infection_Homo sapiens_hsa051320.27888858
99alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.27259087
100Steroid hormone biosynthesis_Homo sapiens_hsa001400.27173674
101Apoptosis_Homo sapiens_hsa042100.27120039
102Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26999739
103Other glycan degradation_Homo sapiens_hsa005110.26957451
104Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.26769276
105Cell cycle_Homo sapiens_hsa041100.26199725
106Ether lipid metabolism_Homo sapiens_hsa005650.23288615
107Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.22020150
108Antigen processing and presentation_Homo sapiens_hsa046120.21492766
109Herpes simplex infection_Homo sapiens_hsa051680.21415650
110HTLV-I infection_Homo sapiens_hsa051660.21008096
111Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.20927919
112Arginine biosynthesis_Homo sapiens_hsa002200.20797372
113Retinol metabolism_Homo sapiens_hsa008300.19926337
114p53 signaling pathway_Homo sapiens_hsa041150.19921434
115Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.19833395
116Viral carcinogenesis_Homo sapiens_hsa052030.18196897
117Asthma_Homo sapiens_hsa053100.17261237
118Alcoholism_Homo sapiens_hsa050340.15723217
119mRNA surveillance pathway_Homo sapiens_hsa030150.14497334
120Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.14406619
121RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.14396960
122Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.12972361
123Viral myocarditis_Homo sapiens_hsa054160.11992809
124Glycosaminoglycan degradation_Homo sapiens_hsa005310.10557760
125Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.08732036
126Acute myeloid leukemia_Homo sapiens_hsa052210.07331832
127Thyroid cancer_Homo sapiens_hsa052160.06908605
128Endocytosis_Homo sapiens_hsa041440.05593205

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