Rank | Gene Set | Z-score |
---|---|---|
1 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.63946038 |
2 | L-phenylalanine catabolic process (GO:0006559) | 7.63946038 |
3 | exogenous drug catabolic process (GO:0042738) | 7.47380539 |
4 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 7.29836336 |
5 | L-phenylalanine metabolic process (GO:0006558) | 7.29836336 |
6 | epoxygenase P450 pathway (GO:0019373) | 6.93774344 |
7 | aromatic amino acid family catabolic process (GO:0009074) | 6.88561494 |
8 | omega-hydroxylase P450 pathway (GO:0097267) | 6.53348789 |
9 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 6.31063054 |
10 | tryptophan catabolic process (GO:0006569) | 6.23713108 |
11 | indole-containing compound catabolic process (GO:0042436) | 6.23713108 |
12 | indolalkylamine catabolic process (GO:0046218) | 6.23713108 |
13 | kynurenine metabolic process (GO:0070189) | 6.08470142 |
14 | bile acid biosynthetic process (GO:0006699) | 5.98626520 |
15 | tryptophan metabolic process (GO:0006568) | 5.86593895 |
16 | glyoxylate metabolic process (GO:0046487) | 5.79302945 |
17 | urea cycle (GO:0000050) | 5.69289354 |
18 | urea metabolic process (GO:0019627) | 5.69289354 |
19 | high-density lipoprotein particle remodeling (GO:0034375) | 5.59794512 |
20 | negative regulation of fibrinolysis (GO:0051918) | 5.59620920 |
21 | alpha-linolenic acid metabolic process (GO:0036109) | 5.55963440 |
22 | complement activation, alternative pathway (GO:0006957) | 5.41923843 |
23 | sulfur amino acid catabolic process (GO:0000098) | 5.41261621 |
24 | regulation of fibrinolysis (GO:0051917) | 5.40264053 |
25 | cysteine metabolic process (GO:0006534) | 5.39937218 |
26 | protein carboxylation (GO:0018214) | 5.38625275 |
27 | peptidyl-glutamic acid carboxylation (GO:0017187) | 5.38625275 |
28 | regulation of protein activation cascade (GO:2000257) | 5.35738397 |
29 | nitrogen cycle metabolic process (GO:0071941) | 5.23566326 |
30 | ethanol metabolic process (GO:0006067) | 5.16457989 |
31 | serine family amino acid catabolic process (GO:0009071) | 5.14078369 |
32 | drug metabolic process (GO:0017144) | 5.10928053 |
33 | bile acid metabolic process (GO:0008206) | 5.10871139 |
34 | regulation of complement activation (GO:0030449) | 5.00800911 |
35 | aromatic amino acid family metabolic process (GO:0009072) | 4.99976467 |
36 | regulation of plasminogen activation (GO:0010755) | 4.90173021 |
37 | phenylpropanoid metabolic process (GO:0009698) | 4.89010723 |
38 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.88924447 |
39 | reverse cholesterol transport (GO:0043691) | 4.87587339 |
40 | regulation of triglyceride catabolic process (GO:0010896) | 4.86924647 |
41 | oxidative demethylation (GO:0070989) | 4.85902318 |
42 | regulation of cholesterol esterification (GO:0010872) | 4.85366934 |
43 | homocysteine metabolic process (GO:0050667) | 4.84225574 |
44 | tyrosine metabolic process (GO:0006570) | 4.83697237 |
45 | plasma lipoprotein particle remodeling (GO:0034369) | 4.77358504 |
46 | protein-lipid complex remodeling (GO:0034368) | 4.77358504 |
47 | macromolecular complex remodeling (GO:0034367) | 4.77358504 |
48 | alpha-amino acid catabolic process (GO:1901606) | 4.67574636 |
49 | acylglycerol homeostasis (GO:0055090) | 4.62472496 |
50 | triglyceride homeostasis (GO:0070328) | 4.62472496 |
51 | negative regulation of sterol transport (GO:0032372) | 4.61625503 |
52 | negative regulation of cholesterol transport (GO:0032375) | 4.61625503 |
53 | amino-acid betaine metabolic process (GO:0006577) | 4.61207030 |
54 | lysine metabolic process (GO:0006553) | 4.60015761 |
55 | lysine catabolic process (GO:0006554) | 4.60015761 |
56 | acute-phase response (GO:0006953) | 4.58864781 |
57 | negative regulation of blood coagulation (GO:0030195) | 4.57202264 |
58 | negative regulation of hemostasis (GO:1900047) | 4.57202264 |
59 | phospholipid efflux (GO:0033700) | 4.56533591 |
60 | negative regulation of protein activation cascade (GO:2000258) | 4.50184067 |
61 | coenzyme catabolic process (GO:0009109) | 4.43738629 |
62 | bile acid and bile salt transport (GO:0015721) | 4.43043516 |
63 | glycine metabolic process (GO:0006544) | 4.42408940 |
64 | indolalkylamine metabolic process (GO:0006586) | 4.41835391 |
65 | cellular ketone body metabolic process (GO:0046950) | 4.40646678 |
66 | imidazole-containing compound metabolic process (GO:0052803) | 4.36048260 |
67 | plasma lipoprotein particle clearance (GO:0034381) | 4.33489127 |
68 | cellular biogenic amine catabolic process (GO:0042402) | 4.33434973 |
69 | amine catabolic process (GO:0009310) | 4.33434973 |
70 | cellular amino acid catabolic process (GO:0009063) | 4.30668042 |
71 | cellular glucuronidation (GO:0052695) | 4.29596256 |
72 | glutamate metabolic process (GO:0006536) | 4.25343108 |
73 | cholesterol efflux (GO:0033344) | 4.21602575 |
74 | regulation of humoral immune response (GO:0002920) | 4.19790842 |
75 | serine family amino acid metabolic process (GO:0009069) | 4.19746539 |
76 | benzene-containing compound metabolic process (GO:0042537) | 4.15767900 |
77 | intestinal cholesterol absorption (GO:0030299) | 4.14980014 |
78 | negative regulation of coagulation (GO:0050819) | 4.14436644 |
79 | ethanol oxidation (GO:0006069) | 4.11848730 |
80 | cellular modified amino acid catabolic process (GO:0042219) | 4.10982395 |
81 | negative regulation of wound healing (GO:0061045) | 4.10403290 |
82 | arginine metabolic process (GO:0006525) | 4.04147816 |
83 | S-adenosylmethionine metabolic process (GO:0046500) | 4.02627335 |
84 | serine family amino acid biosynthetic process (GO:0009070) | 4.02108545 |
85 | aldehyde catabolic process (GO:0046185) | 4.01960490 |
86 | dicarboxylic acid biosynthetic process (GO:0043650) | 4.01557314 |
87 | fibrinolysis (GO:0042730) | 4.00833303 |
88 | low-density lipoprotein particle remodeling (GO:0034374) | 3.97054912 |
89 | negative regulation of complement activation (GO:0045916) | 3.95138528 |
90 | plasma lipoprotein particle assembly (GO:0034377) | 3.94403369 |
91 | drug catabolic process (GO:0042737) | 3.90075771 |
92 | primary alcohol catabolic process (GO:0034310) | 3.84983202 |
93 | blood coagulation, intrinsic pathway (GO:0007597) | 3.83509688 |
94 | uronic acid metabolic process (GO:0006063) | 3.81729197 |
95 | glucuronate metabolic process (GO:0019585) | 3.81729197 |
96 | ketone body metabolic process (GO:1902224) | 3.81523672 |
97 | complement activation, classical pathway (GO:0006958) | 3.80913372 |
98 | cofactor catabolic process (GO:0051187) | 3.80465999 |
99 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.78612609 |
100 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.78612609 |
101 | negative regulation of lipase activity (GO:0060192) | 3.78172572 |
102 | complement activation (GO:0006956) | 3.76283944 |
103 | organic acid catabolic process (GO:0016054) | 3.75519469 |
104 | carboxylic acid catabolic process (GO:0046395) | 3.75519469 |
105 | regulation of apoptotic cell clearance (GO:2000425) | 3.74096026 |
106 | cytolysis (GO:0019835) | 3.73872479 |
107 | protein activation cascade (GO:0072376) | 3.73316124 |
108 | positive regulation of lipid catabolic process (GO:0050996) | 3.72045382 |
109 | regulation of bile acid biosynthetic process (GO:0070857) | 3.71587010 |
110 | cholesterol homeostasis (GO:0042632) | 3.71119414 |
111 | phospholipid homeostasis (GO:0055091) | 3.70915948 |
112 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.70760723 |
113 | alkaloid metabolic process (GO:0009820) | 3.70176718 |
114 | acetyl-CoA metabolic process (GO:0006084) | 3.67408248 |
115 | short-chain fatty acid metabolic process (GO:0046459) | 3.66135819 |
116 | sterol homeostasis (GO:0055092) | 3.65198858 |
117 | positive regulation of hemostasis (GO:1900048) | 3.62773509 |
118 | positive regulation of blood coagulation (GO:0030194) | 3.62773509 |
119 | plasma lipoprotein particle organization (GO:0071827) | 3.61100724 |
120 | regulation of cholesterol homeostasis (GO:2000188) | 3.60940277 |
121 | NAD biosynthetic process (GO:0009435) | 3.57568951 |
122 | protein-lipid complex assembly (GO:0065005) | 3.53373706 |
123 | nicotinamide nucleotide biosynthetic process (GO:0019359) | 3.53229406 |
124 | acute inflammatory response (GO:0002526) | 3.53090526 |
125 | opsonization (GO:0008228) | 3.51643407 |
126 | hormone catabolic process (GO:0042447) | 3.50620578 |
127 | response to mercury ion (GO:0046689) | 3.46885343 |
128 | positive regulation of coagulation (GO:0050820) | 3.36788641 |
129 | proline metabolic process (GO:0006560) | 3.27834850 |
130 | primary alcohol metabolic process (GO:0034308) | 3.27558828 |
131 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 3.27287994 |
132 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 3.26859590 |
133 | flavonoid metabolic process (GO:0009812) | 3.22868398 |
134 | xenobiotic metabolic process (GO:0006805) | 3.20372758 |
135 | heme transport (GO:0015886) | 3.19686133 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 8.37247857 |
2 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 7.16568934 |
3 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 7.05727427 |
4 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.46913114 |
5 | * FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 5.19012763 |
6 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 5.11273274 |
7 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.75773621 |
8 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 4.06116927 |
9 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 4.01902939 |
10 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.46334943 |
11 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.22144242 |
12 | * TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.02027941 |
13 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 11.9850033 |
14 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.96120214 |
15 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.94623474 |
16 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.61553241 |
17 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.56640582 |
18 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.52942189 |
19 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.52166757 |
20 | GATA1_22025678_ChIP-Seq_K562_Human | 1.42954387 |
21 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.40507735 |
22 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.39941984 |
23 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.38325117 |
24 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.38065478 |
25 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.24656657 |
26 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.23948406 |
27 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.23236239 |
28 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.23160009 |
29 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.22870348 |
30 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.19395701 |
31 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.19021364 |
32 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.16484689 |
33 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.06269600 |
34 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.04268175 |
35 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.03242450 |
36 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.02598319 |
37 | * RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.98641961 |
38 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.97993672 |
39 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.96935311 |
40 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.96062511 |
41 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.91680062 |
42 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.88792546 |
43 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.88218664 |
44 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.88016136 |
45 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.85919932 |
46 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.85792643 |
47 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.85792643 |
48 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.85592257 |
49 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.85191407 |
50 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.84258416 |
51 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.82862988 |
52 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.82546120 |
53 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.82330349 |
54 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.82226863 |
55 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.81349520 |
56 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.81222803 |
57 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.77854290 |
58 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.77288827 |
59 | CJUN_26792858_Chip-Seq_BT549_Human | 0.76963434 |
60 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.76643047 |
61 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.75604086 |
62 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.74918549 |
63 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.74780137 |
64 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.74715522 |
65 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.72883863 |
66 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.72852443 |
67 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.72237111 |
68 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.72168303 |
69 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.72150965 |
70 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.71783924 |
71 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.71238240 |
72 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.71203324 |
73 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.71203324 |
74 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.70650680 |
75 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.69297794 |
76 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.69249864 |
77 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.69081737 |
78 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.68869402 |
79 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.68733870 |
80 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.68733870 |
81 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.67926732 |
82 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.66227270 |
83 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.65472265 |
84 | * SMC4_20622854_ChIP-Seq_HELA_Human | 0.65188814 |
85 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.63076840 |
86 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.63009830 |
87 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.62979616 |
88 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.62759966 |
89 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.62396235 |
90 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.61084801 |
91 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.61054418 |
92 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.61034024 |
93 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.60878990 |
94 | * PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.58678887 |
95 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.58235226 |
96 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.56641141 |
97 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.56617524 |
98 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.55371232 |
99 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.54954788 |
100 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.54336062 |
101 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.53871565 |
102 | AR_20517297_ChIP-Seq_VCAP_Human | 0.53223766 |
103 | * CEBPB_22108803_ChIP-Seq_LS180_Human | 0.53155156 |
104 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.53003972 |
105 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.51502995 |
106 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.51363126 |
107 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.50293424 |
108 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.50014776 |
109 | CBP_21632823_ChIP-Seq_H3396_Human | 0.49146332 |
110 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.49084984 |
111 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.48736408 |
112 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.48392464 |
113 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.48050971 |
114 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.47559628 |
115 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.47250483 |
116 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.45869032 |
117 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.45134330 |
118 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.43854016 |
119 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.43377080 |
120 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.43339177 |
121 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.42849559 |
122 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.42620201 |
123 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.41726795 |
124 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.40608698 |
125 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.40143971 |
126 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.40072211 |
127 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.40064377 |
128 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.39629747 |
129 | GATA1_19941826_ChIP-Seq_K562_Human | 0.39527687 |
130 | GATA2_19941826_ChIP-Seq_K562_Human | 0.39435102 |
131 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.39170374 |
132 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.38893222 |
133 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.38451273 |
134 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.37585293 |
135 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.37519179 |
136 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.37221082 |
137 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.36661541 |
138 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 0.35927541 |
139 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.35067808 |
140 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.34854401 |
141 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.34587789 |
142 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.34371998 |
143 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.34357825 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 8.33052138 |
2 | MP0005360_urolithiasis | 7.51721242 |
3 | MP0005085_abnormal_gallbladder_physiolo | 6.46552117 |
4 | MP0005365_abnormal_bile_salt | 6.20000298 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 5.18002209 |
6 | MP0003806_abnormal_nucleotide_metabolis | 4.24421766 |
7 | MP0003252_abnormal_bile_duct | 3.92976345 |
8 | MP0010329_abnormal_lipoprotein_level | 3.57727337 |
9 | MP0009840_abnormal_foam_cell | 3.25406582 |
10 | MP0005083_abnormal_biliary_tract | 3.04448659 |
11 | MP0003195_calcinosis | 2.81941150 |
12 | MP0005332_abnormal_amino_acid | 2.78334032 |
13 | MP0001666_abnormal_nutrient_absorption | 2.62066597 |
14 | MP0003191_abnormal_cellular_cholesterol | 2.31413370 |
15 | MP0000609_abnormal_liver_physiology | 2.15377344 |
16 | MP0004019_abnormal_vitamin_homeostasis | 2.13254429 |
17 | MP0002118_abnormal_lipid_homeostasis | 2.09474002 |
18 | MP0002138_abnormal_hepatobiliary_system | 1.96964088 |
19 | MP0003868_abnormal_feces_composition | 1.95986923 |
20 | MP0005319_abnormal_enzyme/_coenzyme | 1.83871320 |
21 | MP0001764_abnormal_homeostasis | 1.69002152 |
22 | MP0005275_abnormal_skin_tensile | 1.67402281 |
23 | MP0009697_abnormal_copulation | 1.60040425 |
24 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.56399418 |
25 | MP0005451_abnormal_body_composition | 1.46174272 |
26 | MP0003011_delayed_dark_adaptation | 1.36282723 |
27 | MP0000566_synostosis | 1.35975160 |
28 | MP0003186_abnormal_redox_activity | 1.30083201 |
29 | MP0003656_abnormal_erythrocyte_physiolo | 1.28633962 |
30 | MP0009643_abnormal_urine_homeostasis | 1.25252155 |
31 | MP0005647_abnormal_sex_gland | 1.23533255 |
32 | MP0002282_abnormal_trachea_morphology | 1.23050429 |
33 | MP0000598_abnormal_liver_morphology | 1.17218552 |
34 | MP0003705_abnormal_hypodermis_morpholog | 1.11757317 |
35 | MP0009764_decreased_sensitivity_to | 1.10041391 |
36 | MP0000604_amyloidosis | 1.06910537 |
37 | MP0010234_abnormal_vibrissa_follicle | 1.06253216 |
38 | MP0003566_abnormal_cell_adhesion | 1.04509343 |
39 | MP0009763_increased_sensitivity_to | 1.01441971 |
40 | MP0002254_reproductive_system_inflammat | 1.00288307 |
41 | MP0004264_abnormal_extraembryonic_tissu | 0.99172879 |
42 | MP0005023_abnormal_wound_healing | 0.96605659 |
43 | MP0005636_abnormal_mineral_homeostasis | 0.94877369 |
44 | MP0010368_abnormal_lymphatic_system | 0.91858383 |
45 | MP0008469_abnormal_protein_level | 0.89133418 |
46 | MP0009642_abnormal_blood_homeostasis | 0.86893608 |
47 | MP0003941_abnormal_skin_development | 0.85539718 |
48 | MP0005408_hypopigmentation | 0.85300218 |
49 | MP0005501_abnormal_skin_physiology | 0.83028086 |
50 | MP0000467_abnormal_esophagus_morphology | 0.82902585 |
51 | MP0002876_abnormal_thyroid_physiology | 0.81101781 |
52 | MP0009765_abnormal_xenobiotic_induced | 0.80740229 |
53 | MP0002098_abnormal_vibrissa_morphology | 0.80598450 |
54 | MP0006036_abnormal_mitochondrial_physio | 0.80190502 |
55 | MP0009780_abnormal_chondrocyte_physiolo | 0.80034153 |
56 | MP0008438_abnormal_cutaneous_collagen | 0.79883508 |
57 | MP0005376_homeostasis/metabolism_phenot | 0.79415787 |
58 | MP0005670_abnormal_white_adipose | 0.77424091 |
59 | MP0002078_abnormal_glucose_homeostasis | 0.76575074 |
60 | MP0003453_abnormal_keratinocyte_physiol | 0.76211514 |
61 | MP0005220_abnormal_exocrine_pancreas | 0.75661347 |
62 | MP0005084_abnormal_gallbladder_morpholo | 0.75358136 |
63 | MP0005377_hearing/vestibular/ear_phenot | 0.69964728 |
64 | MP0003878_abnormal_ear_physiology | 0.69964728 |
65 | MP0002971_abnormal_brown_adipose | 0.69766459 |
66 | MP0005334_abnormal_fat_pad | 0.68457145 |
67 | MP0002249_abnormal_larynx_morphology | 0.67668162 |
68 | MP0003690_abnormal_glial_cell | 0.67104177 |
69 | MP0005535_abnormal_body_temperature | 0.66429121 |
70 | MP0001216_abnormal_epidermal_layer | 0.66240152 |
71 | MP0004130_abnormal_muscle_cell | 0.65599514 |
72 | MP0001661_extended_life_span | 0.65395389 |
73 | MP0004272_abnormal_basement_membrane | 0.65034104 |
74 | MP0003183_abnormal_peptide_metabolism | 0.64912359 |
75 | MP0009053_abnormal_anal_canal | 0.64665584 |
76 | MP0005409_darkened_coat_color | 0.63206144 |
77 | MP0005266_abnormal_metabolism | 0.62556307 |
78 | MP0001756_abnormal_urination | 0.61589772 |
79 | MP0000639_abnormal_adrenal_gland | 0.60236135 |
80 | MP0004947_skin_inflammation | 0.59791156 |
81 | MP0001915_intracranial_hemorrhage | 0.59701600 |
82 | MP0001851_eye_inflammation | 0.58852795 |
83 | MP0003329_amyloid_beta_deposits | 0.58769805 |
84 | MP0000377_abnormal_hair_follicle | 0.58478538 |
85 | MP0005375_adipose_tissue_phenotype | 0.56817215 |
86 | MP0002166_altered_tumor_susceptibility | 0.54998994 |
87 | MP0006035_abnormal_mitochondrial_morpho | 0.54594578 |
88 | MP0005448_abnormal_energy_balance | 0.53587832 |
89 | MP0005464_abnormal_platelet_physiology | 0.52052328 |
90 | MP0000627_abnormal_mammary_gland | 0.51987589 |
91 | MP0003879_abnormal_hair_cell | 0.50915115 |
92 | MP0003279_aneurysm | 0.50555016 |
93 | MP0005503_abnormal_tendon_morphology | 0.50080484 |
94 | MP0002822_catalepsy | 0.48750996 |
95 | MP0003638_abnormal_response/metabolism_ | 0.47938719 |
96 | MP0005395_other_phenotype | 0.47638945 |
97 | MP0002136_abnormal_kidney_physiology | 0.46890849 |
98 | MP0008874_decreased_physiological_sensi | 0.45947367 |
99 | MP0000858_altered_metastatic_potential | 0.45888864 |
100 | MP0002928_abnormal_bile_duct | 0.45809152 |
101 | MP0009931_abnormal_skin_appearance | 0.45691799 |
102 | MP0004782_abnormal_surfactant_physiolog | 0.45229893 |
103 | MP0006138_congestive_heart_failure | 0.45085234 |
104 | MP0003718_maternal_effect | 0.44929806 |
105 | MP0008873_increased_physiological_sensi | 0.43887769 |
106 | MP0000367_abnormal_coat/_hair | 0.43552211 |
107 | MP0004381_abnormal_hair_follicle | 0.42842657 |
108 | MP0003724_increased_susceptibility_to | 0.41763371 |
109 | MP0003436_decreased_susceptibility_to | 0.41671878 |
110 | MP0005248_abnormal_Harderian_gland | 0.41273055 |
111 | MP0005166_decreased_susceptibility_to | 0.40733778 |
112 | MP0003075_altered_response_to | 0.40600112 |
113 | MP0003953_abnormal_hormone_level | 0.40135668 |
114 | MP0002837_dystrophic_cardiac_calcinosis | 0.39037724 |
115 | MP0008872_abnormal_physiological_respon | 0.37045410 |
116 | MP0009672_abnormal_birth_weight | 0.35945199 |
117 | MP0005666_abnormal_adipose_tissue | 0.35442519 |
118 | MP0000579_abnormal_nail_morphology | 0.34920878 |
119 | MP0009384_cardiac_valve_regurgitation | 0.34148278 |
120 | MP0000230_abnormal_systemic_arterial | 0.33042679 |
121 | MP0002796_impaired_skin_barrier | 0.32651045 |
122 | MP0006082_CNS_inflammation | 0.31523481 |
123 | MP0000249_abnormal_blood_vessel | 0.31157722 |
124 | MP0009115_abnormal_fat_cell | 0.30677022 |
125 | MP0002132_abnormal_respiratory_system | 0.29982597 |
126 | MP0002168_other_aberrant_phenotype | 0.29974377 |
127 | MP0004883_abnormal_blood_vessel | 0.29863138 |
128 | MP0001243_abnormal_dermal_layer | 0.29131215 |
129 | MP0001845_abnormal_inflammatory_respons | 0.28696968 |
130 | MP0001881_abnormal_mammary_gland | 0.28447811 |
131 | MP0002970_abnormal_white_adipose | 0.27945969 |
132 | MP0001853_heart_inflammation | 0.27408455 |
133 | MP0005164_abnormal_response_to | 0.25406061 |
134 | MP0005058_abnormal_lysosome_morphology | 0.24401632 |
135 | MP0002060_abnormal_skin_morphology | 0.23612073 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 7.44808590 |
2 | Deep venous thrombosis (HP:0002625) | 7.41811890 |
3 | Intrahepatic cholestasis (HP:0001406) | 7.34143852 |
4 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 6.72002740 |
5 | Prolonged partial thromboplastin time (HP:0003645) | 6.60694985 |
6 | Hypobetalipoproteinemia (HP:0003563) | 6.43390835 |
7 | Xanthomatosis (HP:0000991) | 6.25273664 |
8 | Hyperlipoproteinemia (HP:0010980) | 5.62961082 |
9 | Complement deficiency (HP:0004431) | 5.46862746 |
10 | Joint hemorrhage (HP:0005261) | 4.79415212 |
11 | Hypolipoproteinemia (HP:0010981) | 4.78702550 |
12 | Hyperammonemia (HP:0001987) | 4.60699872 |
13 | Epidermoid cyst (HP:0200040) | 4.49158560 |
14 | Abnormality of the common coagulation pathway (HP:0010990) | 4.48698786 |
15 | Hyperglycinemia (HP:0002154) | 4.46165762 |
16 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 4.38521861 |
17 | Abnormality of methionine metabolism (HP:0010901) | 4.31004200 |
18 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.29524211 |
19 | Ketosis (HP:0001946) | 4.26510154 |
20 | Fat malabsorption (HP:0002630) | 4.19398158 |
21 | Hypoalphalipoproteinemia (HP:0003233) | 4.17639808 |
22 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.15437064 |
23 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.14631965 |
24 | Abnormality of complement system (HP:0005339) | 3.98034751 |
25 | Hyperglycinuria (HP:0003108) | 3.92869697 |
26 | Abnormality of glycine metabolism (HP:0010895) | 3.92453562 |
27 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.92453562 |
28 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.86145174 |
29 | Abnormality of the intrinsic pathway (HP:0010989) | 3.83784701 |
30 | Hypoglycemic coma (HP:0001325) | 3.79958586 |
31 | Conjugated hyperbilirubinemia (HP:0002908) | 3.76697209 |
32 | Hypercholesterolemia (HP:0003124) | 3.58392495 |
33 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.36840593 |
34 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.35015705 |
35 | Hyperbilirubinemia (HP:0002904) | 3.33042339 |
36 | Steatorrhea (HP:0002570) | 3.22241498 |
37 | Abnormality of serum amino acid levels (HP:0003112) | 3.09397873 |
38 | Delayed CNS myelination (HP:0002188) | 3.08567624 |
39 | Spontaneous abortion (HP:0005268) | 3.06545524 |
40 | Abnormality of nucleobase metabolism (HP:0010932) | 3.06394376 |
41 | Ketoacidosis (HP:0001993) | 2.99879829 |
42 | Hepatocellular carcinoma (HP:0001402) | 2.98310317 |
43 | Hypochromic microcytic anemia (HP:0004840) | 2.96521247 |
44 | Myocardial infarction (HP:0001658) | 2.93077573 |
45 | Right ventricular cardiomyopathy (HP:0011663) | 2.80760238 |
46 | Systemic lupus erythematosus (HP:0002725) | 2.77928907 |
47 | Metabolic acidosis (HP:0001942) | 2.76665971 |
48 | Skin nodule (HP:0200036) | 2.75647210 |
49 | Abnormality of purine metabolism (HP:0004352) | 2.66518977 |
50 | Vascular calcification (HP:0004934) | 2.61977904 |
51 | Lethargy (HP:0001254) | 2.59528050 |
52 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.55088318 |
53 | Dicarboxylic aciduria (HP:0003215) | 2.55088318 |
54 | Acanthocytosis (HP:0001927) | 2.50538117 |
55 | Spastic diplegia (HP:0001264) | 2.46407935 |
56 | Abnormal gallbladder morphology (HP:0012437) | 2.46260879 |
57 | Gout (HP:0001997) | 2.45957378 |
58 | Glomerulonephritis (HP:0000099) | 2.45312359 |
59 | Hypoglycemic seizures (HP:0002173) | 2.43897127 |
60 | Mitral stenosis (HP:0001718) | 2.41346170 |
61 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.40225843 |
62 | Cholelithiasis (HP:0001081) | 2.39933101 |
63 | Cerebral edema (HP:0002181) | 2.39703724 |
64 | Abnormal gallbladder physiology (HP:0012438) | 2.37033823 |
65 | Cholecystitis (HP:0001082) | 2.37033823 |
66 | Neonatal onset (HP:0003623) | 2.34204119 |
67 | Irritability (HP:0000737) | 2.33334144 |
68 | Cardiovascular calcification (HP:0011915) | 2.31946522 |
69 | Purpura (HP:0000979) | 2.30299830 |
70 | Amyloidosis (HP:0011034) | 2.29568891 |
71 | Malnutrition (HP:0004395) | 2.25431016 |
72 | Enlarged kidneys (HP:0000105) | 2.22179194 |
73 | Arthropathy (HP:0003040) | 2.21727525 |
74 | Gangrene (HP:0100758) | 2.20966029 |
75 | Gingival bleeding (HP:0000225) | 2.20886024 |
76 | Esophageal varix (HP:0002040) | 2.18839939 |
77 | Sensorimotor neuropathy (HP:0007141) | 2.17741191 |
78 | Pancreatitis (HP:0001733) | 2.17630223 |
79 | Menorrhagia (HP:0000132) | 2.17053802 |
80 | Brushfield spots (HP:0001088) | 2.13743391 |
81 | Thrombophlebitis (HP:0004418) | 2.08307785 |
82 | Late onset (HP:0003584) | 2.08229454 |
83 | Vomiting (HP:0002013) | 2.05368119 |
84 | Generalized aminoaciduria (HP:0002909) | 2.05112528 |
85 | Opisthotonus (HP:0002179) | 2.03958768 |
86 | Abnormality of the Achilles tendon (HP:0005109) | 2.01672186 |
87 | Abnormality of the gallbladder (HP:0005264) | 2.01100570 |
88 | Abnormal tarsal ossification (HP:0008369) | 1.99274205 |
89 | Hemorrhage of the eye (HP:0011885) | 1.98724272 |
90 | Poikilocytosis (HP:0004447) | 1.97891292 |
91 | Reduced antithrombin III activity (HP:0001976) | 1.97025025 |
92 | Osteomalacia (HP:0002749) | 1.95595959 |
93 | Bifid scrotum (HP:0000048) | 1.95428338 |
94 | Rickets (HP:0002748) | 1.95296644 |
95 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.95105701 |
96 | Abnormality of nail color (HP:0100643) | 1.92624192 |
97 | Pulmonary embolism (HP:0002204) | 1.90246320 |
98 | Fair hair (HP:0002286) | 1.89879183 |
99 | Renal cortical cysts (HP:0000803) | 1.88651624 |
100 | Abnormality of iron homeostasis (HP:0011031) | 1.87819754 |
101 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.87618943 |
102 | Hypophosphatemic rickets (HP:0004912) | 1.87557372 |
103 | Elevated alkaline phosphatase (HP:0003155) | 1.86339069 |
104 | Abnormal cartilage morphology (HP:0002763) | 1.85927066 |
105 | Hydroxyprolinuria (HP:0003080) | 1.85290172 |
106 | Abnormality of proline metabolism (HP:0010907) | 1.85290172 |
107 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.83261720 |
108 | Alkalosis (HP:0001948) | 1.82789043 |
109 | Elevated hepatic transaminases (HP:0002910) | 1.81362287 |
110 | Status epilepticus (HP:0002133) | 1.80635186 |
111 | Abnormality of vitamin metabolism (HP:0100508) | 1.74666425 |
112 | Nephritis (HP:0000123) | 1.73768014 |
113 | Abnormal delivery (HP:0001787) | 1.72572671 |
114 | Neonatal hypoglycemia (HP:0001998) | 1.69204022 |
115 | Hyperglycemia (HP:0003074) | 1.69149583 |
116 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.68546203 |
117 | Generalized hypopigmentation of hair (HP:0011358) | 1.66453145 |
118 | Cerebral palsy (HP:0100021) | 1.65536699 |
119 | Atrioventricular block (HP:0001678) | 1.64762931 |
120 | Abnormality of the axillary hair (HP:0100134) | 1.64705670 |
121 | Abnormality of secondary sexual hair (HP:0009888) | 1.64705670 |
122 | Joint swelling (HP:0001386) | 1.60346937 |
123 | Lymphangioma (HP:0100764) | 1.54287581 |
124 | Stroke (HP:0001297) | 1.52570519 |
125 | Chondrocalcinosis (HP:0000934) | 1.51606115 |
126 | Impaired platelet aggregation (HP:0003540) | 1.47211994 |
127 | Abnormal platelet function (HP:0011869) | 1.47211994 |
128 | Hypophosphatemia (HP:0002148) | 1.46071934 |
129 | Back pain (HP:0003418) | 1.45225349 |
130 | Hyperphosphaturia (HP:0003109) | 1.45221758 |
131 | Alopecia of scalp (HP:0002293) | 1.44325638 |
132 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.44141208 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 7.24458841 |
2 | SIK1 | 4.67535910 |
3 | ERN1 | 4.58150330 |
4 | FGFR4 | 4.49642518 |
5 | EPHA2 | 4.01245616 |
6 | TAOK3 | 3.27067298 |
7 | INSRR | 3.01452910 |
8 | ERBB4 | 2.91770470 |
9 | MYLK | 2.74878311 |
10 | FER | 2.56730880 |
11 | MAP2K4 | 2.30637276 |
12 | MST1R | 2.09758769 |
13 | PKN2 | 2.07077795 |
14 | PIK3CG | 1.87444822 |
15 | MAPK11 | 1.87220817 |
16 | LATS1 | 1.86656119 |
17 | FLT3 | 1.84600372 |
18 | TYK2 | 1.68478295 |
19 | TRIB3 | 1.63617219 |
20 | MAPKAPK3 | 1.62939410 |
21 | FRK | 1.59354499 |
22 | TESK1 | 1.56703834 |
23 | CDK12 | 1.50989565 |
24 | DAPK2 | 1.45655382 |
25 | PTK6 | 1.44393163 |
26 | BRSK2 | 1.43551678 |
27 | ABL2 | 1.42793075 |
28 | NEK9 | 1.41321314 |
29 | EEF2K | 1.40571229 |
30 | FGFR2 | 1.37125777 |
31 | JAK2 | 1.22220016 |
32 | MAP3K7 | 1.21733681 |
33 | KDR | 1.18882109 |
34 | TNK2 | 1.14425363 |
35 | PINK1 | 1.11207227 |
36 | PRKAA2 | 1.07983488 |
37 | STK39 | 1.04474009 |
38 | MAP2K3 | 1.04473129 |
39 | MAP3K14 | 1.04423686 |
40 | TBK1 | 1.04398250 |
41 | MST4 | 1.03841000 |
42 | JAK1 | 1.02201824 |
43 | ERBB2 | 1.00496792 |
44 | DMPK | 0.98706590 |
45 | GRK6 | 0.97402018 |
46 | PDGFRA | 0.96990843 |
47 | TRPM7 | 0.96099898 |
48 | MAPK4 | 0.95196280 |
49 | STK38L | 0.94537285 |
50 | PAK3 | 0.92027595 |
51 | PRKCZ | 0.90490903 |
52 | MAP3K3 | 0.89521330 |
53 | MAP3K10 | 0.86444876 |
54 | MAPK15 | 0.84714351 |
55 | MET | 0.84384967 |
56 | EPHB1 | 0.83450492 |
57 | CDC42BPA | 0.82803282 |
58 | MATK | 0.81753236 |
59 | FGFR1 | 0.80199924 |
60 | CAMK2G | 0.80172373 |
61 | EPHA3 | 0.78293485 |
62 | MAPK12 | 0.77700780 |
63 | TIE1 | 0.73982086 |
64 | PRKACG | 0.73052598 |
65 | CHUK | 0.72553369 |
66 | CDK6 | 0.72474589 |
67 | MAP3K11 | 0.69707755 |
68 | NLK | 0.69239225 |
69 | MAP2K6 | 0.66544487 |
70 | LMTK2 | 0.66171009 |
71 | MARK2 | 0.65814940 |
72 | IRAK3 | 0.65751634 |
73 | PAK2 | 0.65599341 |
74 | CSK | 0.65381204 |
75 | RIPK1 | 0.65314606 |
76 | STK38 | 0.65304534 |
77 | SGK3 | 0.64272149 |
78 | GSK3A | 0.63850524 |
79 | PRKAA1 | 0.63008255 |
80 | LRRK2 | 0.62268402 |
81 | DYRK1B | 0.61437159 |
82 | PRKCI | 0.60873079 |
83 | DDR2 | 0.60804051 |
84 | PDGFRB | 0.60258466 |
85 | CAMK1D | 0.59621074 |
86 | AKT3 | 0.59278184 |
87 | CSF1R | 0.58421295 |
88 | MAPK7 | 0.58124697 |
89 | MAP3K12 | 0.56385521 |
90 | IKBKE | 0.56162477 |
91 | FGFR3 | 0.55142454 |
92 | TGFBR2 | 0.54851877 |
93 | PRKD1 | 0.54406646 |
94 | PRKCQ | 0.52533355 |
95 | NTRK3 | 0.50989137 |
96 | PTK2 | 0.50323955 |
97 | EIF2AK3 | 0.49919433 |
98 | SGK2 | 0.49374833 |
99 | MUSK | 0.49330840 |
100 | PDPK1 | 0.49109985 |
101 | GRK1 | 0.47301967 |
102 | CSNK1G1 | 0.47050728 |
103 | EPHA4 | 0.46060641 |
104 | PKN1 | 0.44248674 |
105 | HIPK2 | 0.43720599 |
106 | MAP2K1 | 0.43257256 |
107 | MAPKAPK2 | 0.43153525 |
108 | TAOK2 | 0.42993219 |
109 | BMX | 0.42773609 |
110 | IGF1R | 0.42661536 |
111 | RPS6KA2 | 0.41877678 |
112 | MAPK3 | 0.40093788 |
113 | MAP3K5 | 0.39870100 |
114 | MAP3K13 | 0.39404367 |
115 | PRKCG | 0.36967964 |
116 | EIF2AK1 | 0.36426864 |
117 | RET | 0.36333643 |
118 | CSNK1E | 0.35444389 |
119 | SGK223 | 0.35147004 |
120 | SGK494 | 0.35147004 |
121 | SGK1 | 0.34242635 |
122 | MAP3K6 | 0.33606459 |
123 | CDK4 | 0.33462083 |
124 | SIK3 | 0.32399234 |
125 | EGFR | 0.32285932 |
126 | MTOR | 0.31762651 |
127 | ICK | 0.31481547 |
128 | CAMK4 | 0.31284910 |
129 | PBK | 0.30629078 |
130 | PDK1 | 0.28905540 |
131 | PIK3CA | 0.28084028 |
132 | IRAK2 | 0.28005491 |
133 | MAP2K2 | 0.27452918 |
134 | CSNK1G2 | 0.27018997 |
135 | IRAK1 | 0.25998745 |
136 | PRKCA | 0.25967777 |
137 | LATS2 | 0.24644638 |
138 | MAP3K1 | 0.23548620 |
139 | CSNK1G3 | 0.23402771 |
140 | MAP3K2 | 0.20455429 |
141 | ABL1 | 0.19696710 |
142 | PDK3 | 0.18475394 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.55804058 |
2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.54027464 |
3 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.39978315 |
4 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.37359146 |
5 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.09022836 |
6 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.77778903 |
7 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.69437191 |
8 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.66807105 |
9 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.61187047 |
10 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.54714955 |
11 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.47643162 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.39105929 |
13 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.27876544 |
14 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.14630892 |
15 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.14117698 |
16 | Peroxisome_Homo sapiens_hsa04146 | 2.08923668 |
17 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.96146231 |
18 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.95256883 |
19 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.93524388 |
20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.92323888 |
21 | Histidine metabolism_Homo sapiens_hsa00340 | 1.90649723 |
22 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.85469026 |
23 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.78401514 |
24 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.76726635 |
25 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.75599111 |
26 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.75552680 |
27 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.74914831 |
28 | Retinol metabolism_Homo sapiens_hsa00830 | 1.71829780 |
29 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.70918314 |
30 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.66455772 |
31 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.59352980 |
32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.57356549 |
33 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.56328944 |
34 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.50435909 |
35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.49478353 |
36 | Bile secretion_Homo sapiens_hsa04976 | 1.48475663 |
37 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.44329624 |
38 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.39497032 |
39 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.34648580 |
40 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.34323373 |
41 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.32025501 |
42 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.28731640 |
43 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.21759761 |
44 | ABC transporters_Homo sapiens_hsa02010 | 1.19878198 |
45 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.19542381 |
46 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.17866189 |
47 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.14631837 |
48 | Carbon metabolism_Homo sapiens_hsa01200 | 1.10774866 |
49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.09238596 |
50 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.99967416 |
51 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.97648014 |
52 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.97383766 |
53 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.96910194 |
54 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.95349188 |
55 | Sulfur relay system_Homo sapiens_hsa04122 | 0.95152834 |
56 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.87377182 |
57 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.84989354 |
58 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.83576663 |
59 | Lysine degradation_Homo sapiens_hsa00310 | 0.81957063 |
60 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.74935815 |
61 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.68138208 |
62 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.66505284 |
63 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.65474508 |
64 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.55928316 |
65 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.51162063 |
66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46294230 |
67 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.43517973 |
68 | Prion diseases_Homo sapiens_hsa05020 | 0.38394695 |
69 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.37529155 |
70 | Pertussis_Homo sapiens_hsa05133 | 0.35740892 |
71 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.25292594 |
72 | Other glycan degradation_Homo sapiens_hsa00511 | 0.25109478 |
73 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.24863461 |
74 | Galactose metabolism_Homo sapiens_hsa00052 | 0.23890836 |
75 | Insulin resistance_Homo sapiens_hsa04931 | 0.22506950 |
76 | Mineral absorption_Homo sapiens_hsa04978 | 0.22174928 |
77 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.22040791 |
78 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.20984295 |
79 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.17983827 |
80 | Circadian rhythm_Homo sapiens_hsa04710 | 0.16979827 |
81 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.15159695 |
82 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.14447848 |
83 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.09380657 |
84 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.07845296 |
85 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.01103481 |
86 | Bladder cancer_Homo sapiens_hsa05219 | -0.2457060 |
87 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | -0.2448642 |
88 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | -0.2401413 |
89 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.2277502 |
90 | Amoebiasis_Homo sapiens_hsa05146 | -0.2170618 |
91 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.1817111 |
92 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | -0.1734240 |
93 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.1713886 |
94 | Renin-angiotensin system_Homo sapiens_hsa04614 | -0.1649504 |
95 | Tight junction_Homo sapiens_hsa04530 | -0.1622025 |
96 | Hepatitis C_Homo sapiens_hsa05160 | -0.1608099 |
97 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.1586365 |
98 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.1528864 |
99 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | -0.1470220 |
100 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.1456825 |
101 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.1250623 |
102 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.1139135 |
103 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.1121811 |
104 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | -0.0904477 |
105 | Prostate cancer_Homo sapiens_hsa05215 | -0.0895353 |
106 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0736744 |
107 | Pancreatic secretion_Homo sapiens_hsa04972 | -0.0647176 |
108 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.0641099 |
109 | Serotonergic synapse_Homo sapiens_hsa04726 | -0.0609705 |
110 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | -0.0562488 |
111 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | -0.0484386 |
112 | Protein digestion and absorption_Homo sapiens_hsa04974 | -0.0440277 |
113 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | -0.0387245 |