Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 6.35834158 |
2 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.35834158 |
3 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.79051114 |
4 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.77438077 |
5 | negative regulation of cell killing (GO:0031342) | 5.77438077 |
6 | ribosomal small subunit assembly (GO:0000028) | 5.18639394 |
7 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.87981224 |
8 | response to interferon-beta (GO:0035456) | 4.64209857 |
9 | response to interferon-alpha (GO:0035455) | 4.32303213 |
10 | type I interferon signaling pathway (GO:0060337) | 4.31696735 |
11 | cellular response to type I interferon (GO:0071357) | 4.31696735 |
12 | response to type I interferon (GO:0034340) | 4.31075024 |
13 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 4.29761655 |
14 | regulation of regulatory T cell differentiation (GO:0045589) | 4.20149534 |
15 | immunoglobulin mediated immune response (GO:0016064) | 4.19085332 |
16 | regulation of T cell tolerance induction (GO:0002664) | 4.10998571 |
17 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.06883930 |
18 | viral transcription (GO:0019083) | 4.05515739 |
19 | positive regulation of B cell differentiation (GO:0045579) | 3.99077451 |
20 | positive thymic T cell selection (GO:0045059) | 3.94594484 |
21 | cytidine metabolic process (GO:0046087) | 3.93002658 |
22 | cytidine catabolic process (GO:0006216) | 3.93002658 |
23 | cytidine deamination (GO:0009972) | 3.93002658 |
24 | DNA deamination (GO:0045006) | 3.89301755 |
25 | regulation of tolerance induction (GO:0002643) | 3.84307527 |
26 | translational termination (GO:0006415) | 3.84226179 |
27 | defense response to protozoan (GO:0042832) | 3.80659330 |
28 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.71983408 |
29 | detection of other organism (GO:0098543) | 3.70597722 |
30 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.70552311 |
31 | positive T cell selection (GO:0043368) | 3.66461367 |
32 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.64881695 |
33 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.64881695 |
34 | modulation by symbiont of host immune response (GO:0052553) | 3.64881695 |
35 | positive regulation by symbiont of host defense response (GO:0052509) | 3.64881695 |
36 | modulation by symbiont of host defense response (GO:0052031) | 3.64881695 |
37 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.64881695 |
38 | B cell mediated immunity (GO:0019724) | 3.62170790 |
39 | regulation of B cell differentiation (GO:0045577) | 3.62141976 |
40 | negative regulation of interleukin-12 production (GO:0032695) | 3.61934407 |
41 | platelet dense granule organization (GO:0060155) | 3.60583479 |
42 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.60420950 |
43 | detection of bacterium (GO:0016045) | 3.59721000 |
44 | response to protozoan (GO:0001562) | 3.59603098 |
45 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.58824549 |
46 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.58824549 |
47 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.56122359 |
48 | positive regulation of tolerance induction (GO:0002645) | 3.55451238 |
49 | negative regulation of T cell mediated immunity (GO:0002710) | 3.55115783 |
50 | neutrophil activation (GO:0042119) | 3.51008782 |
51 | regulation of gamma-delta T cell activation (GO:0046643) | 3.49571619 |
52 | definitive hemopoiesis (GO:0060216) | 3.46962390 |
53 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.43828360 |
54 | cellular response to interferon-beta (GO:0035458) | 3.43283632 |
55 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.42277239 |
56 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.40769153 |
57 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.37081569 |
58 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.36773432 |
59 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.36156240 |
60 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.34870905 |
61 | mature B cell differentiation involved in immune response (GO:0002313) | 3.34738390 |
62 | T cell selection (GO:0045058) | 3.33288722 |
63 | cotranslational protein targeting to membrane (GO:0006613) | 3.32525916 |
64 | protein targeting to ER (GO:0045047) | 3.31523080 |
65 | thymic T cell selection (GO:0045061) | 3.30645502 |
66 | myeloid dendritic cell activation (GO:0001773) | 3.29617237 |
67 | translational elongation (GO:0006414) | 3.27095864 |
68 | granulocyte activation (GO:0036230) | 3.24751152 |
69 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.23498752 |
70 | macrophage activation involved in immune response (GO:0002281) | 3.23329151 |
71 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.23311602 |
72 | detection of external biotic stimulus (GO:0098581) | 3.22892694 |
73 | dendritic cell chemotaxis (GO:0002407) | 3.22043842 |
74 | tolerance induction (GO:0002507) | 3.21365702 |
75 | NIK/NF-kappaB signaling (GO:0038061) | 3.20859758 |
76 | mast cell activation (GO:0045576) | 3.19347425 |
77 | ribosomal small subunit biogenesis (GO:0042274) | 3.18826090 |
78 | * regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.18666678 |
79 | protein localization to endoplasmic reticulum (GO:0070972) | 3.18074336 |
80 | cellular extravasation (GO:0045123) | 3.17690439 |
81 | myeloid cell activation involved in immune response (GO:0002275) | 3.16972350 |
82 | regulation of natural killer cell differentiation (GO:0032823) | 3.16479918 |
83 | lymph node development (GO:0048535) | 3.15598971 |
84 | regulation of necroptotic process (GO:0060544) | 3.15356553 |
85 | leukocyte aggregation (GO:0070486) | 3.15008327 |
86 | microglial cell activation (GO:0001774) | 3.14827191 |
87 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.14717987 |
88 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.13939381 |
89 | T cell costimulation (GO:0031295) | 3.13748084 |
90 | T cell receptor signaling pathway (GO:0050852) | 3.13446762 |
91 | * positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.12578923 |
92 | activated T cell proliferation (GO:0050798) | 3.12509203 |
93 | positive regulation of interferon-alpha production (GO:0032727) | 3.12328927 |
94 | lymphocyte costimulation (GO:0031294) | 3.12078199 |
95 | positive regulation of macrophage differentiation (GO:0045651) | 3.11880276 |
96 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 3.10902608 |
97 | * interferon-gamma-mediated signaling pathway (GO:0060333) | 3.10624665 |
98 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.10174830 |
99 | dendritic cell migration (GO:0036336) | 3.09523663 |
100 | myeloid dendritic cell differentiation (GO:0043011) | 3.09462812 |
101 | response to peptidoglycan (GO:0032494) | 3.06260467 |
102 | detection of molecule of bacterial origin (GO:0032490) | 3.05845799 |
103 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.05722817 |
104 | cellular response to zinc ion (GO:0071294) | 3.05600595 |
105 | lymphocyte chemotaxis (GO:0048247) | 3.05050513 |
106 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.03474183 |
107 | respiratory burst (GO:0045730) | 3.00302005 |
108 | negative regulation of viral genome replication (GO:0045071) | 3.00269005 |
109 | viral life cycle (GO:0019058) | 2.99596032 |
110 | regulation of interferon-alpha production (GO:0032647) | 2.96646508 |
111 | leukocyte degranulation (GO:0043299) | 2.96585900 |
112 | regulation of RIG-I signaling pathway (GO:0039535) | 2.96247949 |
113 | mature B cell differentiation (GO:0002335) | 2.95519246 |
114 | positive regulation of antigen processing and presentation (GO:0002579) | 2.93668843 |
115 | * regulation of cell killing (GO:0031341) | 2.93295002 |
116 | negative thymic T cell selection (GO:0045060) | 2.93238333 |
117 | response to interleukin-15 (GO:0070672) | 2.92445346 |
118 | mucosal-associated lymphoid tissue development (GO:0048537) | 2.91999596 |
119 | Peyers patch development (GO:0048541) | 2.91999596 |
120 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.91298352 |
121 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.90767335 |
122 | T cell migration (GO:0072678) | 2.90662197 |
123 | detection of biotic stimulus (GO:0009595) | 2.90181685 |
124 | positive regulation of mast cell activation (GO:0033005) | 2.89951138 |
125 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.88296733 |
126 | T cell homeostasis (GO:0043029) | 2.86449199 |
127 | endosome to pigment granule transport (GO:0043485) | 2.83964645 |
128 | endosome to melanosome transport (GO:0035646) | 2.83964645 |
129 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.83917266 |
130 | neutrophil activation involved in immune response (GO:0002283) | 2.83839586 |
131 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.82723734 |
132 | regulation of response to interferon-gamma (GO:0060330) | 2.81757971 |
133 | cellular response to interleukin-15 (GO:0071350) | 2.81435805 |
134 | negative T cell selection (GO:0043383) | 2.81156476 |
135 | regulation of natural killer cell activation (GO:0032814) | 2.80895145 |
136 | regulation of necrotic cell death (GO:0010939) | 2.80798835 |
137 | B cell receptor signaling pathway (GO:0050853) | 2.78679822 |
138 | regulation of respiratory burst (GO:0060263) | 2.77636519 |
139 | dendritic cell differentiation (GO:0097028) | 2.75979581 |
140 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.72396036 |
141 | cellular protein complex disassembly (GO:0043624) | 2.72379523 |
142 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.70989199 |
143 | megakaryocyte development (GO:0035855) | 2.70146092 |
144 | necroptotic process (GO:0070266) | 2.68723062 |
145 | negative regulation of necroptotic process (GO:0060546) | 2.68651228 |
146 | * antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.68414725 |
147 | * regulation of T cell mediated cytotoxicity (GO:0001914) | 2.67470398 |
148 | interferon-gamma production (GO:0032609) | 2.65968171 |
149 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 2.65312678 |
150 | maturation of SSU-rRNA (GO:0030490) | 2.63314243 |
151 | natural killer cell activation (GO:0030101) | 2.63105318 |
152 | secretory granule organization (GO:0033363) | 2.62343414 |
153 | regulation of antigen processing and presentation (GO:0002577) | 2.59397647 |
154 | * positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.58428114 |
155 | lymphoid progenitor cell differentiation (GO:0002320) | 2.58097885 |
156 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.55580080 |
157 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 2.53504561 |
158 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.51947036 |
159 | positive regulation of natural killer cell activation (GO:0032816) | 2.51781358 |
160 | cellular response to exogenous dsRNA (GO:0071360) | 2.51575582 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.63338422 |
2 | * IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 4.23439033 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.71005857 |
4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.52031288 |
5 | * IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.49386309 |
6 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.40903557 |
7 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.28066062 |
8 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.26812997 |
9 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 3.03153745 |
10 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 3.01321672 |
11 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.99870078 |
12 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.85601243 |
13 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.71423021 |
14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.60315013 |
15 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.58900148 |
16 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.58479635 |
17 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.32941620 |
18 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.31080264 |
19 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.30029601 |
20 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.27169354 |
21 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.26883816 |
22 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.26726412 |
23 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.26302529 |
24 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.24301648 |
25 | GATA1_22025678_ChIP-Seq_K562_Human | 2.18594818 |
26 | * MYB_26560356_Chip-Seq_TH2_Human | 2.18186332 |
27 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.12048282 |
28 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.11030288 |
29 | MAF_26560356_Chip-Seq_TH1_Human | 2.08170796 |
30 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.05093029 |
31 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.03632058 |
32 | MYC_22102868_ChIP-Seq_BL_Human | 2.00007389 |
33 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.96838826 |
34 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.95284521 |
35 | * MYB_26560356_Chip-Seq_TH1_Human | 1.93141934 |
36 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.91188262 |
37 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.90745238 |
38 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.88358652 |
39 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.85072573 |
40 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.82335568 |
41 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.82163361 |
42 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.81309876 |
43 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.79682643 |
44 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.77875775 |
45 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.75162011 |
46 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.74535312 |
47 | UTX_26944678_Chip-Seq_JUKART_Human | 1.69061420 |
48 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.66163785 |
49 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.64749372 |
50 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.59663052 |
51 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.57455122 |
52 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.55188231 |
53 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.54798304 |
54 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.53667850 |
55 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.50786475 |
56 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.45073080 |
57 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.42740836 |
58 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.41512523 |
59 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.40637069 |
60 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.40471327 |
61 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.34428654 |
62 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.34238595 |
63 | MAF_26560356_Chip-Seq_TH2_Human | 1.32555654 |
64 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.27966485 |
65 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.23448600 |
66 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.22449747 |
67 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.21339258 |
68 | SPI1_23127762_ChIP-Seq_K562_Human | 1.21027207 |
69 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.20790217 |
70 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.19732335 |
71 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.19570339 |
72 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.18417023 |
73 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.17757089 |
74 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.17694153 |
75 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.15487428 |
76 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.14732427 |
77 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.14429469 |
78 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.12860170 |
79 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.09381154 |
80 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.09069655 |
81 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.06251021 |
82 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.05300219 |
83 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.04621989 |
84 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.03125021 |
85 | * GATA3_26560356_Chip-Seq_TH2_Human | 1.03019784 |
86 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.01986723 |
87 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.01700040 |
88 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.00201903 |
89 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99710358 |
90 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.99150711 |
91 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.96377576 |
92 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.96334987 |
93 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.95675783 |
94 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.95552869 |
95 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.93681739 |
96 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.93463581 |
97 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.93283525 |
98 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.92135284 |
99 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.90772900 |
100 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.90405297 |
101 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.90100693 |
102 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.89669815 |
103 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89607799 |
104 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.89246892 |
105 | * ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 0.87286883 |
106 | GATA3_26560356_Chip-Seq_TH1_Human | 0.87094503 |
107 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.86837402 |
108 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.86724131 |
109 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.86386814 |
110 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.86089756 |
111 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.85556021 |
112 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.82852052 |
113 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.82353711 |
114 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.81954998 |
115 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.81272578 |
116 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.81117737 |
117 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.77396031 |
118 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.77142545 |
119 | GATA1_19941826_ChIP-Seq_K562_Human | 0.76931459 |
120 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.76531598 |
121 | P300_27268052_Chip-Seq_Bcells_Human | 0.75661092 |
122 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.75207726 |
123 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.74274709 |
124 | GATA2_19941826_ChIP-Seq_K562_Human | 0.71449525 |
125 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.69155813 |
126 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.68436858 |
127 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.68082577 |
128 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.67944615 |
129 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.66172436 |
130 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.66022948 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * MP0001835_abnormal_antigen_presentation | 4.37480870 |
2 | * MP0009785_altered_susceptibility_to | 3.50744520 |
3 | * MP0000685_abnormal_immune_system | 3.36375485 |
4 | * MP0005671_abnormal_response_to | 3.30825223 |
5 | MP0003724_increased_susceptibility_to | 3.08254191 |
6 | MP0002166_altered_tumor_susceptibility | 2.93506904 |
7 | * MP0005025_abnormal_response_to | 2.87014016 |
8 | MP0003763_abnormal_thymus_physiology | 2.83847542 |
9 | MP0002396_abnormal_hematopoietic_system | 2.75587521 |
10 | MP0002148_abnormal_hypersensitivity_rea | 2.69811380 |
11 | MP0005387_immune_system_phenotype | 2.69730499 |
12 | MP0001790_abnormal_immune_system | 2.69730499 |
13 | * MP0001800_abnormal_humoral_immune | 2.69326667 |
14 | MP0003436_decreased_susceptibility_to | 2.68935752 |
15 | * MP0005000_abnormal_immune_tolerance | 2.64367558 |
16 | * MP0002723_abnormal_immune_serum | 2.53121817 |
17 | * MP0002452_abnormal_antigen_presenting | 2.50415961 |
18 | * MP0002420_abnormal_adaptive_immunity | 2.45940077 |
19 | * MP0001819_abnormal_immune_cell | 2.44264895 |
20 | MP0002006_tumorigenesis | 2.40133212 |
21 | MP0002419_abnormal_innate_immunity | 2.36669198 |
22 | MP0005464_abnormal_platelet_physiology | 2.33125412 |
23 | * MP0002398_abnormal_bone_marrow | 2.25868226 |
24 | MP0006082_CNS_inflammation | 2.21606908 |
25 | MP0001853_heart_inflammation | 2.13956113 |
26 | MP0001873_stomach_inflammation | 2.08821261 |
27 | * MP0000716_abnormal_immune_system | 2.07773981 |
28 | MP0005397_hematopoietic_system_phenotyp | 2.03281597 |
29 | MP0001545_abnormal_hematopoietic_system | 2.03281597 |
30 | * MP0010155_abnormal_intestine_physiology | 1.96119011 |
31 | MP0002405_respiratory_system_inflammati | 1.90578378 |
32 | * MP0000689_abnormal_spleen_morphology | 1.87482662 |
33 | MP0009333_abnormal_splenocyte_physiolog | 1.85205571 |
34 | * MP0002722_abnormal_immune_system | 1.84866886 |
35 | * MP0002429_abnormal_blood_cell | 1.79513005 |
36 | MP0004808_abnormal_hematopoietic_stem | 1.75003238 |
37 | * MP0001845_abnormal_inflammatory_respons | 1.71193846 |
38 | MP0005174_abnormal_tail_pigmentation | 1.69724222 |
39 | MP0000465_gastrointestinal_hemorrhage | 1.63837966 |
40 | MP0005075_abnormal_melanosome_morpholog | 1.60620676 |
41 | * MP0008469_abnormal_protein_level | 1.57009884 |
42 | * MP0004947_skin_inflammation | 1.49452384 |
43 | MP0000490_abnormal_crypts_of | 1.44459817 |
44 | MP0004510_myositis | 1.42412190 |
45 | MP0005310_abnormal_salivary_gland | 1.41915818 |
46 | MP0000703_abnormal_thymus_morphology | 1.40604577 |
47 | MP0009764_decreased_sensitivity_to | 1.38242097 |
48 | MP0002254_reproductive_system_inflammat | 1.37642726 |
49 | MP0001533_abnormal_skeleton_physiology | 1.36969988 |
50 | MP0003191_abnormal_cellular_cholesterol | 1.31868178 |
51 | MP0003300_gastrointestinal_ulcer | 1.31813203 |
52 | * MP0003866_abnormal_defecation | 1.25634982 |
53 | MP0000858_altered_metastatic_potential | 1.23774110 |
54 | MP0002277_abnormal_respiratory_mucosa | 1.23600699 |
55 | MP0006054_spinal_hemorrhage | 1.23382260 |
56 | MP0002933_joint_inflammation | 1.23010436 |
57 | MP0009379_abnormal_foot_pigmentation | 1.18649148 |
58 | MP0002095_abnormal_skin_pigmentation | 1.18476468 |
59 | MP0000343_altered_response_to | 1.17806199 |
60 | MP0005058_abnormal_lysosome_morphology | 1.14837552 |
61 | MP0003806_abnormal_nucleotide_metabolis | 1.13895799 |
62 | MP0003045_fibrosis | 1.10753237 |
63 | MP0002132_abnormal_respiratory_system | 1.07804005 |
64 | MP0003183_abnormal_peptide_metabolism | 1.06237402 |
65 | MP0004883_abnormal_blood_vessel | 1.00789882 |
66 | MP0009763_increased_sensitivity_to | 1.00310298 |
67 | MP0003186_abnormal_redox_activity | 1.00203496 |
68 | MP0009278_abnormal_bone_marrow | 0.98980621 |
69 | MP0003656_abnormal_erythrocyte_physiolo | 0.98279385 |
70 | MP0004147_increased_porphyrin_level | 0.96210788 |
71 | MP0003448_altered_tumor_morphology | 0.95982905 |
72 | MP0003303_peritoneal_inflammation | 0.95641580 |
73 | MP0001348_abnormal_lacrimal_gland | 0.94902056 |
74 | * MP0002019_abnormal_tumor_incidence | 0.91102466 |
75 | MP0001851_eye_inflammation | 0.89905963 |
76 | MP0003172_abnormal_lysosome_physiology | 0.89061839 |
77 | MP0005164_abnormal_response_to | 0.87329006 |
78 | MP0005451_abnormal_body_composition | 0.85198519 |
79 | MP0008007_abnormal_cellular_replicative | 0.84005771 |
80 | MP0002138_abnormal_hepatobiliary_system | 0.82868953 |
81 | MP0003828_pulmonary_edema | 0.82190539 |
82 | MP0000569_abnormal_digit_pigmentation | 0.81353405 |
83 | MP0000604_amyloidosis | 0.80634175 |
84 | MP0002009_preneoplasia | 0.80165837 |
85 | MP0009840_abnormal_foam_cell | 0.79158654 |
86 | MP0002163_abnormal_gland_morphology | 0.78797074 |
87 | MP0000015_abnormal_ear_pigmentation | 0.78501239 |
88 | MP0003252_abnormal_bile_duct | 0.77258425 |
89 | MP0002998_abnormal_bone_remodeling | 0.76300840 |
90 | * MP0002693_abnormal_pancreas_physiology | 0.73381644 |
91 | MP0009765_abnormal_xenobiotic_induced | 0.72669397 |
92 | MP0004381_abnormal_hair_follicle | 0.68934940 |
93 | MP0008260_abnormal_autophagy | 0.68054622 |
94 | MP0003075_altered_response_to | 0.67980786 |
95 | MP0001765_abnormal_ion_homeostasis | 0.67313895 |
96 | MP0001663_abnormal_digestive_system | 0.67190222 |
97 | MP0003943_abnormal_hepatobiliary_system | 0.66149137 |
98 | MP0005319_abnormal_enzyme/_coenzyme | 0.64711471 |
99 | MP0003690_abnormal_glial_cell | 0.63842143 |
100 | MP0000249_abnormal_blood_vessel | 0.62905598 |
101 | MP0008004_abnormal_stomach_pH | 0.62203070 |
102 | MP0000598_abnormal_liver_morphology | 0.62118615 |
103 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.61300087 |
104 | MP0001986_abnormal_taste_sensitivity | 0.60782359 |
105 | MP0004782_abnormal_surfactant_physiolog | 0.60759992 |
106 | MP0003795_abnormal_bone_structure | 0.60445394 |
107 | * MP0000609_abnormal_liver_physiology | 0.59446807 |
108 | MP0008872_abnormal_physiological_respon | 0.59349805 |
109 | MP0005390_skeleton_phenotype | 0.58698589 |
110 | MP0005166_decreased_susceptibility_to | 0.58070537 |
111 | MP0005167_abnormal_blood-brain_barrier | 0.57803065 |
112 | MP0005023_abnormal_wound_healing | 0.57748024 |
113 | MP0010352_gastrointestinal_tract_polyps | 0.57012068 |
114 | MP0003693_abnormal_embryo_hatching | 0.56981397 |
115 | MP0001764_abnormal_homeostasis | 0.56869615 |
116 | MP0001879_abnormal_lymphatic_vessel | 0.56681668 |
117 | MP0002136_abnormal_kidney_physiology | 0.56679513 |
118 | MP0010368_abnormal_lymphatic_system | 0.56650842 |
119 | MP0003638_abnormal_response/metabolism_ | 0.55704105 |
120 | MP0000372_irregular_coat_pigmentation | 0.55021101 |
121 | MP0009643_abnormal_urine_homeostasis | 0.53234867 |
122 | MP0005379_endocrine/exocrine_gland_phen | 0.53053533 |
123 | MP0002876_abnormal_thyroid_physiology | 0.50866307 |
124 | MP0000920_abnormal_myelination | 0.50724168 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.43949319 |
2 | Myositis (HP:0100614) | 4.79086645 |
3 | Chronic otitis media (HP:0000389) | 4.43674121 |
4 | Recurrent abscess formation (HP:0002722) | 4.30270246 |
5 | Thrombocytosis (HP:0001894) | 4.26210823 |
6 | IgM deficiency (HP:0002850) | 4.25125667 |
7 | Recurrent bronchitis (HP:0002837) | 4.07625498 |
8 | Eczematoid dermatitis (HP:0000976) | 4.01075687 |
9 | Gastrointestinal infarctions (HP:0005244) | 3.95314307 |
10 | Recurrent bacterial skin infections (HP:0005406) | 3.85132701 |
11 | Aplastic anemia (HP:0001915) | 3.81092447 |
12 | Recurrent fungal infections (HP:0002841) | 3.51694854 |
13 | Abnormality of T cell physiology (HP:0011840) | 3.50983901 |
14 | Abnormality of the nasal mucosa (HP:0000433) | 3.45338218 |
15 | Orchitis (HP:0100796) | 3.37733989 |
16 | Nasal polyposis (HP:0100582) | 3.37680032 |
17 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.37395614 |
18 | Recurrent cutaneous fungal infections (HP:0011370) | 3.37395614 |
19 | Petechiae (HP:0000967) | 3.32644041 |
20 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.27051784 |
21 | Abnormality of macrophages (HP:0004311) | 3.26859597 |
22 | Abnormality of T cells (HP:0002843) | 3.26276673 |
23 | Recurrent skin infections (HP:0001581) | 3.25246131 |
24 | Abnormal number of erythroid precursors (HP:0012131) | 3.22047200 |
25 | Recurrent viral infections (HP:0004429) | 3.20598505 |
26 | Prolonged bleeding time (HP:0003010) | 3.19313145 |
27 | Chest pain (HP:0100749) | 3.10011285 |
28 | Vasculitis (HP:0002633) | 3.00680700 |
29 | Retrobulbar optic neuritis (HP:0100654) | 3.00630897 |
30 | Optic neuritis (HP:0100653) | 3.00630897 |
31 | Epistaxis (HP:0000421) | 2.99822326 |
32 | Panhypogammaglobulinemia (HP:0003139) | 2.97680474 |
33 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.94809660 |
34 | Eosinophilia (HP:0001880) | 2.91068688 |
35 | Meningitis (HP:0001287) | 2.89346805 |
36 | Gangrene (HP:0100758) | 2.88551078 |
37 | Agammaglobulinemia (HP:0004432) | 2.87314098 |
38 | Autoimmune hemolytic anemia (HP:0001890) | 2.87215075 |
39 | Abnormality of B cell number (HP:0010975) | 2.83266340 |
40 | B lymphocytopenia (HP:0010976) | 2.83266340 |
41 | Reticulocytopenia (HP:0001896) | 2.82900287 |
42 | Increased IgM level (HP:0003496) | 2.81581562 |
43 | Lymphopenia (HP:0001888) | 2.81278024 |
44 | Mediastinal lymphadenopathy (HP:0100721) | 2.79371339 |
45 | Pulmonary embolism (HP:0002204) | 2.78898108 |
46 | Vacuolated lymphocytes (HP:0001922) | 2.78727787 |
47 | Stomatitis (HP:0010280) | 2.77569799 |
48 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.76050323 |
49 | Interstitial pulmonary disease (HP:0006530) | 2.75406117 |
50 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.75377241 |
51 | Joint swelling (HP:0001386) | 2.74816042 |
52 | Hypergammaglobulinemia (HP:0010702) | 2.74775181 |
53 | Urticaria (HP:0001025) | 2.72032852 |
54 | Abnormality of the pleura (HP:0002103) | 2.69423887 |
55 | Abnormality of T cell number (HP:0011839) | 2.69261579 |
56 | Autoimmune thrombocytopenia (HP:0001973) | 2.66922907 |
57 | Gastrointestinal stroma tumor (HP:0100723) | 2.66446729 |
58 | Anorexia (HP:0002039) | 2.65716123 |
59 | Cellulitis (HP:0100658) | 2.64088579 |
60 | Reduced antithrombin III activity (HP:0001976) | 2.62077990 |
61 | T lymphocytopenia (HP:0005403) | 2.61021677 |
62 | Inflammation of the large intestine (HP:0002037) | 2.60231193 |
63 | Spontaneous hematomas (HP:0007420) | 2.57372636 |
64 | Severe combined immunodeficiency (HP:0004430) | 2.55481252 |
65 | Gastrointestinal inflammation (HP:0004386) | 2.54775577 |
66 | * IgG deficiency (HP:0004315) | 2.54167010 |
67 | Pustule (HP:0200039) | 2.50673912 |
68 | Poikiloderma (HP:0001029) | 2.50406246 |
69 | Abnormal platelet function (HP:0011869) | 2.48379033 |
70 | Impaired platelet aggregation (HP:0003540) | 2.48379033 |
71 | Chronic diarrhea (HP:0002028) | 2.47627322 |
72 | Thyroiditis (HP:0100646) | 2.47210922 |
73 | Gingival bleeding (HP:0000225) | 2.45180244 |
74 | Microcytic anemia (HP:0001935) | 2.41168755 |
75 | Colitis (HP:0002583) | 2.40752729 |
76 | Hemoptysis (HP:0002105) | 2.39586890 |
77 | Hypoplasia of the thymus (HP:0000778) | 2.37297341 |
78 | Pallor (HP:0000980) | 2.32583428 |
79 | Purpura (HP:0000979) | 2.32343218 |
80 | Increased IgE level (HP:0003212) | 2.32153454 |
81 | Leukocytosis (HP:0001974) | 2.31949307 |
82 | Chronic obstructive pulmonary disease (HP:0006510) | 2.31741564 |
83 | Obstructive lung disease (HP:0006536) | 2.31741564 |
84 | Acute hepatic failure (HP:0006554) | 2.31060335 |
85 | Arterial thrombosis (HP:0004420) | 2.30645503 |
86 | Episodic fever (HP:0001954) | 2.30630033 |
87 | Glomerulopathy (HP:0100820) | 2.30024389 |
88 | Skin rash (HP:0000988) | 2.29613730 |
89 | Encephalitis (HP:0002383) | 2.29191207 |
90 | Bronchitis (HP:0012387) | 2.28289160 |
91 | Polyneuropathy (HP:0001271) | 2.27946691 |
92 | Combined immunodeficiency (HP:0005387) | 2.27479433 |
93 | Recurrent sinusitis (HP:0011108) | 2.27387834 |
94 | Abnormality of the prostate (HP:0008775) | 2.26239972 |
95 | Lymphoma (HP:0002665) | 2.26239916 |
96 | Abnormality of eosinophils (HP:0001879) | 2.22131871 |
97 | Chronic sinusitis (HP:0011109) | 2.21124069 |
98 | Muscle fiber atrophy (HP:0100295) | 2.21063848 |
99 | Pulmonary infiltrates (HP:0002113) | 2.18727749 |
100 | Type 2 muscle fiber atrophy (HP:0003554) | 2.18055713 |
101 | IgA deficiency (HP:0002720) | 2.17376517 |
102 | Type I transferrin isoform profile (HP:0003642) | 2.17363424 |
103 | Albinism (HP:0001022) | 2.15740614 |
104 | Keratitis (HP:0000491) | 2.15532206 |
105 | Periodontitis (HP:0000704) | 2.14754169 |
106 | Keratoconjunctivitis (HP:0001096) | 2.14331305 |
107 | Erythema (HP:0010783) | 2.13674488 |
108 | Keratoconjunctivitis sicca (HP:0001097) | 2.07300757 |
109 | Granulocytopenia (HP:0001913) | 2.05455317 |
110 | Neutropenia (HP:0001875) | 2.03516368 |
111 | Recurrent pneumonia (HP:0006532) | 2.02558451 |
112 | Abnormality of glycolipid metabolism (HP:0010969) | 2.02421167 |
113 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.02421167 |
114 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.02421167 |
115 | Vertigo (HP:0002321) | 2.01558512 |
116 | Gingivitis (HP:0000230) | 2.01538401 |
117 | Recurrent lower respiratory tract infections (HP:0002783) | 1.98901845 |
118 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.98811111 |
119 | Basal ganglia calcification (HP:0002135) | 1.97876082 |
120 | Pulmonary fibrosis (HP:0002206) | 1.95818119 |
121 | Abnormality of the pericardium (HP:0001697) | 1.95457381 |
122 | Alveolar cell carcinoma (HP:0006519) | 1.95201673 |
123 | Arthralgia (HP:0002829) | 1.94123759 |
124 | Hepatosplenomegaly (HP:0001433) | 1.88535612 |
125 | Increased serum ferritin (HP:0003281) | 1.85359692 |
126 | Thrombophlebitis (HP:0004418) | 1.83357952 |
127 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.83281889 |
128 | Osteomyelitis (HP:0002754) | 1.82688085 |
129 | Systemic lupus erythematosus (HP:0002725) | 1.80921614 |
130 | Skin ulcer (HP:0200042) | 1.80794940 |
131 | Abnormality of the endocardium (HP:0004306) | 1.80276477 |
132 | Sepsis (HP:0100806) | 1.79543169 |
133 | Amaurosis fugax (HP:0100576) | 1.79398072 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP4K1 | 3.56877264 |
2 | KIT | 3.37279814 |
3 | NME2 | 2.94702237 |
4 | TXK | 2.90875755 |
5 | TBK1 | 2.86046931 |
6 | IKBKE | 2.72129442 |
7 | JAK3 | 2.67052572 |
8 | FLT3 | 2.56059570 |
9 | TYK2 | 2.46796211 |
10 | KDR | 2.46542363 |
11 | TEC | 2.40723412 |
12 | MAP3K12 | 2.23596348 |
13 | ZAP70 | 2.20248238 |
14 | BMPR2 | 2.20130336 |
15 | BTK | 2.16504921 |
16 | MAP3K14 | 2.10299658 |
17 | IRAK4 | 1.99129119 |
18 | BLK | 1.95334125 |
19 | PIM2 | 1.93857838 |
20 | TGFBR2 | 1.86033950 |
21 | CSF1R | 1.81644758 |
22 | TGFBR1 | 1.78496678 |
23 | ERN1 | 1.77654217 |
24 | IKBKB | 1.71246912 |
25 | TNIK | 1.66842029 |
26 | FGFR4 | 1.62484804 |
27 | NLK | 1.60363535 |
28 | SYK | 1.57239223 |
29 | JAK1 | 1.48647841 |
30 | MAP2K3 | 1.46474685 |
31 | STK16 | 1.45974343 |
32 | MUSK | 1.39545329 |
33 | LCK | 1.32522017 |
34 | ACVR1B | 1.28827935 |
35 | LRRK2 | 1.28473410 |
36 | TIE1 | 1.18815821 |
37 | TAOK3 | 1.15791044 |
38 | LYN | 1.15432494 |
39 | GRK7 | 1.14829941 |
40 | CDK19 | 1.14274141 |
41 | IRAK3 | 1.11667973 |
42 | ITK | 1.11128233 |
43 | EEF2K | 1.08628689 |
44 | MATK | 1.07372195 |
45 | MYLK | 1.06057759 |
46 | RIPK4 | 1.05061421 |
47 | FRK | 1.04518154 |
48 | RPS6KA4 | 1.02534556 |
49 | FGR | 1.01058575 |
50 | PRKCQ | 0.99307530 |
51 | TLK1 | 0.97888810 |
52 | HCK | 0.96970027 |
53 | PIM1 | 0.87286549 |
54 | FGFR3 | 0.86907913 |
55 | ADRBK2 | 0.86724409 |
56 | CHUK | 0.83291689 |
57 | MAP2K6 | 0.83250601 |
58 | SCYL2 | 0.83219144 |
59 | EIF2AK1 | 0.82583983 |
60 | MARK3 | 0.82372965 |
61 | STK10 | 0.82143154 |
62 | FES | 0.78712208 |
63 | BCKDK | 0.78710760 |
64 | DYRK3 | 0.78449706 |
65 | RPS6KB2 | 0.76318409 |
66 | PRKG2 | 0.75427630 |
67 | MAPKAPK3 | 0.75382655 |
68 | MAP3K13 | 0.75243230 |
69 | VRK1 | 0.74043091 |
70 | GRK6 | 0.73622893 |
71 | JAK2 | 0.72519227 |
72 | TNK2 | 0.72281766 |
73 | MST4 | 0.69515269 |
74 | CSK | 0.69323346 |
75 | EIF2AK3 | 0.68208690 |
76 | PDK1 | 0.66250014 |
77 | PRPF4B | 0.66166383 |
78 | CAMKK2 | 0.65784030 |
79 | WEE1 | 0.64051310 |
80 | FYN | 0.62138002 |
81 | MAP3K11 | 0.61784915 |
82 | MAP3K1 | 0.60621238 |
83 | MAPKAPK5 | 0.59780675 |
84 | PTK2B | 0.56596103 |
85 | MAPK11 | 0.56248502 |
86 | TESK2 | 0.54616925 |
87 | RAF1 | 0.52654657 |
88 | PKN2 | 0.51731982 |
89 | NEK9 | 0.51453968 |
90 | TAOK1 | 0.49665845 |
91 | EIF2AK2 | 0.47300459 |
92 | DAPK2 | 0.46699195 |
93 | MAP4K2 | 0.45906268 |
94 | EPHA3 | 0.45514863 |
95 | CAMKK1 | 0.44290903 |
96 | PAK4 | 0.43793458 |
97 | IGF1R | 0.43397147 |
98 | MAPK4 | 0.41111386 |
99 | CDK4 | 0.40612981 |
100 | ILK | 0.39701346 |
101 | PIK3CG | 0.39373633 |
102 | YES1 | 0.38800315 |
103 | PRKCD | 0.38326441 |
104 | GRK1 | 0.38273766 |
105 | MAP3K5 | 0.38204166 |
106 | MAP3K3 | 0.37972600 |
107 | EPHB1 | 0.37723830 |
108 | TAOK2 | 0.37106636 |
109 | IRAK1 | 0.37075175 |
110 | MAPK7 | 0.36775869 |
111 | RPS6KA5 | 0.35601700 |
112 | ABL1 | 0.32785021 |
113 | DAPK1 | 0.32740418 |
114 | MAPK12 | 0.32114436 |
115 | CAMK1 | 0.31765158 |
116 | CDK8 | 0.31719900 |
117 | MAP3K7 | 0.31346580 |
118 | MAPKAPK2 | 0.31162653 |
119 | BRSK2 | 0.31013124 |
120 | OXSR1 | 0.30985990 |
121 | GRK5 | 0.30930875 |
122 | NUAK1 | 0.30877851 |
123 | HIPK2 | 0.29525350 |
124 | EGFR | 0.29134908 |
125 | TRPM7 | 0.29022192 |
126 | SIK3 | 0.27847296 |
127 | DYRK1B | 0.27740602 |
128 | PDPK1 | 0.27476154 |
129 | MAP3K2 | 0.25598032 |
130 | INSR | 0.23339739 |
131 | PASK | 0.22787242 |
132 | ADRBK1 | 0.22007786 |
133 | MAP2K2 | 0.21763453 |
134 | CLK1 | 0.21744767 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.91131765 |
2 | Ribosome_Homo sapiens_hsa03010 | 3.40370082 |
3 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.85804794 |
4 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.60480603 |
5 | Leishmaniasis_Homo sapiens_hsa05140 | 2.54798016 |
6 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.46681091 |
7 | Allograft rejection_Homo sapiens_hsa05330 | 2.42145824 |
8 | Measles_Homo sapiens_hsa05162 | 2.39165636 |
9 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.37349743 |
10 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.32331179 |
11 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.09722867 |
12 | DNA replication_Homo sapiens_hsa03030 | 2.05408169 |
13 | * Antigen processing and presentation_Homo sapiens_hsa04612 | 1.92310039 |
14 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.86799862 |
15 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.84374855 |
16 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.81489496 |
17 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.75163901 |
18 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.69477665 |
19 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.66703112 |
20 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.64304410 |
21 | Asthma_Homo sapiens_hsa05310 | 1.58780728 |
22 | Malaria_Homo sapiens_hsa05144 | 1.55828616 |
23 | Legionellosis_Homo sapiens_hsa05134 | 1.55075337 |
24 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.51968365 |
25 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.50698875 |
26 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.49947960 |
27 | Pertussis_Homo sapiens_hsa05133 | 1.45106007 |
28 | Proteasome_Homo sapiens_hsa03050 | 1.38984449 |
29 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.38809663 |
30 | Influenza A_Homo sapiens_hsa05164 | 1.36177931 |
31 | Base excision repair_Homo sapiens_hsa03410 | 1.34160812 |
32 | Other glycan degradation_Homo sapiens_hsa00511 | 1.32688085 |
33 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.31246788 |
34 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.31070617 |
35 | Shigellosis_Homo sapiens_hsa05131 | 1.23308703 |
36 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.21224860 |
37 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.17084260 |
38 | Sulfur relay system_Homo sapiens_hsa04122 | 1.15204999 |
39 | Mismatch repair_Homo sapiens_hsa03430 | 1.15110256 |
40 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.15067275 |
41 | Phagosome_Homo sapiens_hsa04145 | 1.13670842 |
42 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.13125547 |
43 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.11369397 |
44 | Tuberculosis_Homo sapiens_hsa05152 | 1.10519329 |
45 | Apoptosis_Homo sapiens_hsa04210 | 1.10032762 |
46 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.07675426 |
47 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.07248700 |
48 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.05572257 |
49 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.03137882 |
50 | Homologous recombination_Homo sapiens_hsa03440 | 1.02951741 |
51 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.01965188 |
52 | Hepatitis B_Homo sapiens_hsa05161 | 0.98724104 |
53 | Protein export_Homo sapiens_hsa03060 | 0.96822850 |
54 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.96641853 |
55 | Viral myocarditis_Homo sapiens_hsa05416 | 0.91160402 |
56 | Salmonella infection_Homo sapiens_hsa05132 | 0.91048561 |
57 | Platelet activation_Homo sapiens_hsa04611 | 0.90344006 |
58 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.86309312 |
59 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.85778479 |
60 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.84681661 |
61 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.84489041 |
62 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.80291724 |
63 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.79956455 |
64 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.79785146 |
65 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.79400551 |
66 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.76375243 |
67 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.74833190 |
68 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.74774578 |
69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.74622911 |
70 | Hepatitis C_Homo sapiens_hsa05160 | 0.74024174 |
71 | RNA polymerase_Homo sapiens_hsa03020 | 0.70564561 |
72 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.66307544 |
73 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.65478267 |
74 | Spliceosome_Homo sapiens_hsa03040 | 0.65121541 |
75 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.64307596 |
76 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.63738677 |
77 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.62508770 |
78 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.62230440 |
79 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.60450936 |
80 | Lysosome_Homo sapiens_hsa04142 | 0.60307636 |
81 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.59639315 |
82 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.58046580 |
83 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.52555233 |
84 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.51344141 |
85 | HTLV-I infection_Homo sapiens_hsa05166 | 0.49920151 |
86 | RNA degradation_Homo sapiens_hsa03018 | 0.49044033 |
87 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.48875529 |
88 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.47217575 |
89 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.46297068 |
90 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.45717601 |
91 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.43650226 |
92 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.41908951 |
93 | Endocytosis_Homo sapiens_hsa04144 | 0.41809066 |
94 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.40380672 |
95 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.40242050 |
96 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.39744536 |
97 | ABC transporters_Homo sapiens_hsa02010 | 0.38463587 |
98 | Thyroid cancer_Homo sapiens_hsa05216 | 0.38386060 |
99 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.37245562 |
100 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.34794744 |
101 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.32945282 |
102 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.32932475 |
103 | Galactose metabolism_Homo sapiens_hsa00052 | 0.32181437 |
104 | Purine metabolism_Homo sapiens_hsa00230 | 0.31869692 |
105 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.31147519 |
106 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.30338309 |
107 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.30139384 |
108 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.28294003 |
109 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.28034148 |
110 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.27596786 |
111 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.27237782 |
112 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.27198602 |
113 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.26319927 |
114 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.25682431 |
115 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.24507642 |
116 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.24139676 |
117 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.24092608 |
118 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.23870416 |
119 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.17892794 |
120 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.16588734 |
121 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.16013018 |
122 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.12356418 |
123 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.10843141 |
124 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.10264148 |
125 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.07228019 |
126 | Insulin resistance_Homo sapiens_hsa04931 | 0.06197783 |
127 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.04991621 |
128 | Phototransduction_Homo sapiens_hsa04744 | 0.04341195 |
129 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.04142926 |
130 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.03233349 |
131 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.02562998 |