B3GAT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)6.03551833
2presynaptic membrane assembly (GO:0097105)5.38607761
3vocalization behavior (GO:0071625)5.08001644
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.89732146
5protein localization to synapse (GO:0035418)4.89065556
6neuronal action potential propagation (GO:0019227)4.88903993
7postsynaptic membrane organization (GO:0001941)4.82713987
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.80393107
9presynaptic membrane organization (GO:0097090)4.76880793
10behavioral response to nicotine (GO:0035095)4.67984340
11synaptic vesicle exocytosis (GO:0016079)4.65634710
12ionotropic glutamate receptor signaling pathway (GO:0035235)4.60273630
13regulation of short-term neuronal synaptic plasticity (GO:0048172)4.57302861
14regulation of synaptic vesicle exocytosis (GO:2000300)4.37493522
15regulation of glutamate receptor signaling pathway (GO:1900449)4.36033265
16synaptic vesicle maturation (GO:0016188)4.28394075
17neuron recognition (GO:0008038)4.21434435
18locomotory exploration behavior (GO:0035641)4.20803634
19glutamate receptor signaling pathway (GO:0007215)4.20031440
20positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.16546221
21negative regulation of synaptic transmission, GABAergic (GO:0032229)4.13801281
22regulation of respiratory gaseous exchange by neurological system process (GO:0002087)4.00833033
23gamma-aminobutyric acid transport (GO:0015812)3.99340186
24regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.95601625
25synaptic transmission, glutamatergic (GO:0035249)3.91277196
26gamma-aminobutyric acid signaling pathway (GO:0007214)3.89910313
27positive regulation of membrane potential (GO:0045838)3.87624441
28positive regulation of synapse assembly (GO:0051965)3.83178301
29neurotransmitter secretion (GO:0007269)3.82861023
30regulation of synaptic vesicle transport (GO:1902803)3.81567303
31glutamate secretion (GO:0014047)3.72410737
32neuron-neuron synaptic transmission (GO:0007270)3.69569586
33layer formation in cerebral cortex (GO:0021819)3.65461103
34positive regulation of synaptic transmission, GABAergic (GO:0032230)3.64601588
35transmission of nerve impulse (GO:0019226)3.64545114
36axonal fasciculation (GO:0007413)3.59558032
37regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.57525812
38exploration behavior (GO:0035640)3.52494213
39neurotransmitter transport (GO:0006836)3.52363690
40neurotransmitter-gated ion channel clustering (GO:0072578)3.50631602
41regulation of respiratory system process (GO:0044065)3.48635939
42regulation of long-term neuronal synaptic plasticity (GO:0048169)3.37868847
43C4-dicarboxylate transport (GO:0015740)3.31593287
44regulation of synaptic transmission, GABAergic (GO:0032228)3.30643372
45dendritic spine morphogenesis (GO:0060997)3.30477852
46long-term memory (GO:0007616)3.28553169
47membrane hyperpolarization (GO:0060081)3.27520209
48protein polyglutamylation (GO:0018095)3.26207481
49cerebellar granule cell differentiation (GO:0021707)3.24262471
50regulation of respiratory gaseous exchange (GO:0043576)3.24210167
51central nervous system myelination (GO:0022010)3.23807297
52axon ensheathment in central nervous system (GO:0032291)3.23807297
53negative regulation of astrocyte differentiation (GO:0048712)3.21123091
54dendrite morphogenesis (GO:0048813)3.20877567
55regulation of excitatory postsynaptic membrane potential (GO:0060079)3.20204884
56mechanosensory behavior (GO:0007638)3.19095082
57membrane depolarization during action potential (GO:0086010)3.18669511
58negative regulation of neurotransmitter transport (GO:0051589)3.18544089
59auditory behavior (GO:0031223)3.16819770
60negative regulation of cytosolic calcium ion concentration (GO:0051481)3.16400427
61synapse assembly (GO:0007416)3.15402254
62long-term synaptic potentiation (GO:0060291)3.14708850
63regulation of neuronal synaptic plasticity (GO:0048168)3.14447998
64response to histamine (GO:0034776)3.13003470
65regulation of postsynaptic membrane potential (GO:0060078)3.07798812
66regulation of synaptic transmission, glutamatergic (GO:0051966)3.07184815
67G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.06849751
68regulation of neurotransmitter levels (GO:0001505)3.05166504
69positive regulation of action potential (GO:0045760)3.04988266
70serotonin metabolic process (GO:0042428)3.04974448
71regulation of synapse assembly (GO:0051963)3.04930566
72cerebral cortex radially oriented cell migration (GO:0021799)3.04542328
73synaptic vesicle docking involved in exocytosis (GO:0016081)3.04502751
74regulation of neurotransmitter secretion (GO:0046928)2.97789356
75L-amino acid import (GO:0043092)2.97551001
76negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.96148603
77regulation of meiosis I (GO:0060631)2.95912983
78neurotransmitter uptake (GO:0001504)2.95309239
79positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.94468189
80positive regulation of meiosis (GO:0045836)2.93558543
81pyrimidine nucleobase catabolic process (GO:0006208)2.92622308
82negative regulation of neurotransmitter secretion (GO:0046929)2.91358357
83primary amino compound metabolic process (GO:1901160)2.91274970
84proline transport (GO:0015824)2.91054070
85regulation of neurotransmitter uptake (GO:0051580)2.90637116
86retinal cone cell development (GO:0046549)2.89679571
87positive regulation of potassium ion transmembrane transport (GO:1901381)2.89591779
88detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.89381134
89neuronal action potential (GO:0019228)2.89269413
90amino acid import (GO:0043090)2.87003958
91regulation of glutamate secretion (GO:0014048)2.86838734
92nucleobase catabolic process (GO:0046113)2.86616833
93membrane assembly (GO:0071709)2.86565406
94cell migration in hindbrain (GO:0021535)2.85237202
95piRNA metabolic process (GO:0034587)2.85038087
96regulation of dendritic spine morphogenesis (GO:0061001)2.84999354
97positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.83806726
98intraspecies interaction between organisms (GO:0051703)2.83140586
99social behavior (GO:0035176)2.83140586
100learning (GO:0007612)2.83009022
101protein localization to cilium (GO:0061512)2.82466794
102membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.82403141
103fucose catabolic process (GO:0019317)2.81664661
104L-fucose metabolic process (GO:0042354)2.81664661
105L-fucose catabolic process (GO:0042355)2.81664661
106ATP hydrolysis coupled proton transport (GO:0015991)2.80918495
107energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.80918495
108somite development (GO:0061053)2.79455654
109regulation of synapse structural plasticity (GO:0051823)2.79346654
110cell proliferation in forebrain (GO:0021846)2.79265100
111response to auditory stimulus (GO:0010996)2.78925403
112startle response (GO:0001964)2.78029484
113positive regulation of neurotransmitter secretion (GO:0001956)2.77954904
114cerebellar Purkinje cell differentiation (GO:0021702)2.77523112
115positive regulation of neurotransmitter transport (GO:0051590)2.77489069
116cellular potassium ion homeostasis (GO:0030007)2.76977981
117regulation of dendritic spine development (GO:0060998)2.76913267
118synapse organization (GO:0050808)2.76582858
119regulation of synaptic plasticity (GO:0048167)2.76323710
120positive regulation of synapse maturation (GO:0090129)2.75348728
121protein-cofactor linkage (GO:0018065)2.75237548
122regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.75139413
123positive regulation of oligodendrocyte differentiation (GO:0048714)2.74759281
124response to amphetamine (GO:0001975)2.74595692
125retinal ganglion cell axon guidance (GO:0031290)2.74567947
126regulation of neurotransmitter transport (GO:0051588)2.74484747
127regulation of vesicle fusion (GO:0031338)2.73684852
128regulation of clathrin-mediated endocytosis (GO:2000369)2.72671741
129positive regulation of meiotic cell cycle (GO:0051446)2.68944215
130negative regulation of transcription regulatory region DNA binding (GO:2000678)2.66773874
131response to pheromone (GO:0019236)2.66342112
132otic vesicle formation (GO:0030916)2.63972164
133response to gravity (GO:0009629)2.58437759
134behavioral response to ethanol (GO:0048149)2.57649857
135atrial cardiac muscle cell action potential (GO:0086014)2.57356502
136adaptation of signaling pathway (GO:0023058)2.57032521
137dopamine biosynthetic process (GO:0042416)2.56484413
138nonmotile primary cilium assembly (GO:0035058)2.51596466
139regulation of action potential (GO:0098900)2.51025691
140potassium ion import (GO:0010107)2.49199993
141regulation of collateral sprouting (GO:0048670)2.48851949
142endoderm formation (GO:0001706)2.47879592
143detection of light stimulus involved in sensory perception (GO:0050962)2.47190221
144detection of light stimulus involved in visual perception (GO:0050908)2.47190221
145photoreceptor cell development (GO:0042461)2.46864283
146action potential (GO:0001508)2.45707561
147DNA deamination (GO:0045006)2.45530764
148synaptic transmission, cholinergic (GO:0007271)2.45522914
149behavioral defense response (GO:0002209)2.44950538
150behavioral fear response (GO:0001662)2.44950538
151neurofilament cytoskeleton organization (GO:0060052)2.42401429
152DNA methylation involved in gamete generation (GO:0043046)2.42149581
153negative regulation of appetite (GO:0032099)2.42049295
154negative regulation of response to food (GO:0032096)2.42049295
155adult walking behavior (GO:0007628)2.40669544
156indole-containing compound metabolic process (GO:0042430)2.39767461
157appendage development (GO:0048736)2.39133461
158limb development (GO:0060173)2.39133461
159DNA double-strand break processing (GO:0000729)2.37792322
160neuromuscular synaptic transmission (GO:0007274)2.37641236
161anterograde axon cargo transport (GO:0008089)2.37160057
162reflex (GO:0060004)2.36967947
163axoneme assembly (GO:0035082)2.36896561

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.75113303
2* GBX2_23144817_ChIP-Seq_PC3_Human4.45886527
3* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.12310728
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.99989837
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.92841625
6TAF15_26573619_Chip-Seq_HEK293_Human2.77012736
7* EZH2_27304074_Chip-Seq_ESCs_Mouse2.71563477
8* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.58929477
9AR_21572438_ChIP-Seq_LNCaP_Human2.48903515
10SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.46103011
11* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.45208308
12* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.45208308
13* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.41802144
14* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.36330357
15CTBP1_25329375_ChIP-Seq_LNCAP_Human2.32525583
16* EED_16625203_ChIP-ChIP_MESCs_Mouse2.30810839
17CTBP2_25329375_ChIP-Seq_LNCAP_Human2.30300494
18* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.23070730
19REST_21632747_ChIP-Seq_MESCs_Mouse2.21844482
20GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.20480272
21ZFP57_27257070_Chip-Seq_ESCs_Mouse2.17401168
22* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.13572271
23VDR_22108803_ChIP-Seq_LS180_Human2.01429344
24TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.00457741
25* EZH2_27294783_Chip-Seq_ESCs_Mouse1.99765256
26GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.97615271
27* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.96758759
28* RNF2_27304074_Chip-Seq_ESCs_Mouse1.90622499
29SALL1_21062744_ChIP-ChIP_HESCs_Human1.89657564
30DROSHA_22980978_ChIP-Seq_HELA_Human1.85030652
31P300_19829295_ChIP-Seq_ESCs_Human1.83924195
32* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.82380451
33PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.81574509
34ZNF274_21170338_ChIP-Seq_K562_Hela1.78559937
35SMAD4_21799915_ChIP-Seq_A2780_Human1.73002564
36REST_18959480_ChIP-ChIP_MESCs_Mouse1.72638985
37CBX2_27304074_Chip-Seq_ESCs_Mouse1.71835409
38FUS_26573619_Chip-Seq_HEK293_Human1.71795790
39NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.70649067
40SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.65562065
41* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.65245878
42MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.61366559
43OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.60058931
44PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.60048877
45RNF2_27304074_Chip-Seq_NSC_Mouse1.58739688
46SMAD3_21741376_ChIP-Seq_EPCs_Human1.58392629
47CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.58252687
48RARB_27405468_Chip-Seq_BRAIN_Mouse1.57110072
49PIAS1_25552417_ChIP-Seq_VCAP_Human1.55606250
50SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.55377839
51BMI1_23680149_ChIP-Seq_NPCS_Mouse1.51772456
52IKZF1_21737484_ChIP-ChIP_HCT116_Human1.51727914
53ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.49710940
54RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.48931012
55ER_23166858_ChIP-Seq_MCF-7_Human1.45637490
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.44800238
57MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44338176
58AR_25329375_ChIP-Seq_VCAP_Human1.41410668
59STAT6_21828071_ChIP-Seq_BEAS2B_Human1.38610349
60* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.36545618
61MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.35334464
62IRF1_19129219_ChIP-ChIP_H3396_Human1.31977637
63CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.30783467
64IGF1R_20145208_ChIP-Seq_DFB_Human1.28905912
65PCGF2_27294783_Chip-Seq_NPCs_Mouse1.28659028
66CBP_20019798_ChIP-Seq_JUKART_Human1.28428377
67IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.28428377
68AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.28011179
69* FLI1_27457419_Chip-Seq_LIVER_Mouse1.27717485
70UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27669951
71PRDM14_20953172_ChIP-Seq_ESCs_Human1.27366676
72TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.25555267
73* EZH2_27294783_Chip-Seq_NPCs_Mouse1.24853512
74* NFE2_27457419_Chip-Seq_LIVER_Mouse1.23916360
75* CDX2_19796622_ChIP-Seq_MESCs_Mouse1.23731461
76* NANOG_18555785_Chip-Seq_ESCs_Mouse1.22700559
77* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.21784951
78SOX2_21211035_ChIP-Seq_LN229_Gbm1.21714945
79EWS_26573619_Chip-Seq_HEK293_Human1.19769568
80TCF4_22108803_ChIP-Seq_LS180_Human1.19304435
81* P53_22127205_ChIP-Seq_FIBROBLAST_Human1.17918212
82ARNT_22903824_ChIP-Seq_MCF-7_Human1.17403667
83STAT3_23295773_ChIP-Seq_U87_Human1.17174847
84EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.15480087
85* JUN_21703547_ChIP-Seq_K562_Human1.15077514
86GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.15030988
87HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.14610321
88* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.14303524
89* RING1B_27294783_Chip-Seq_ESCs_Mouse1.14222231
90RUNX2_22187159_ChIP-Seq_PCA_Human1.13486832
91FLI1_21867929_ChIP-Seq_TH2_Mouse1.12143042
92ZNF217_24962896_ChIP-Seq_MCF-7_Human1.12129632
93* TP53_22573176_ChIP-Seq_HFKS_Human1.10796715
94AHR_22903824_ChIP-Seq_MCF-7_Human1.10643870
95* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.10299426
96VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.10255468
97NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10179557
98TCF4_23295773_ChIP-Seq_U87_Human1.09425153
99TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09330671
100TAL1_26923725_Chip-Seq_HPCs_Mouse1.08689453
101SOX2_19829295_ChIP-Seq_ESCs_Human1.07931609
102NANOG_19829295_ChIP-Seq_ESCs_Human1.07931609
103SMAD_19615063_ChIP-ChIP_OVARY_Human1.07732538
104POU5F1_16153702_ChIP-ChIP_HESCs_Human1.07443654
105* CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07357903
106* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06748508
107TP53_18474530_ChIP-ChIP_U2OS_Human1.05769146
108* E2F1_18555785_Chip-Seq_ESCs_Mouse1.05695287
109SMAD4_21741376_ChIP-Seq_EPCs_Human1.05565015
110NR3C1_23031785_ChIP-Seq_PC12_Mouse1.03619614
111BCAT_22108803_ChIP-Seq_LS180_Human1.03104545
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03025721
113POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.03025721
114TP53_16413492_ChIP-PET_HCT116_Human1.02469047
115* P53_22387025_ChIP-Seq_ESCs_Mouse1.02085427
116ERG_21242973_ChIP-ChIP_JURKAT_Human1.01608503
117* CMYC_18555785_Chip-Seq_ESCs_Mouse1.01452575
118HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.97924338
119* RING1B_27294783_Chip-Seq_NPCs_Mouse0.97481370
120* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97249086
121AR_19668381_ChIP-Seq_PC3_Human0.96207617
122* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95609093
123* SUZ12_18555785_Chip-Seq_ESCs_Mouse0.92905532

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern6.13937238
2MP0004859_abnormal_synaptic_plasticity4.34437084
3MP0003635_abnormal_synaptic_transmissio3.53720371
4MP0009745_abnormal_behavioral_response3.23388866
5MP0002064_seizures3.18946814
6MP0009046_muscle_twitch3.16717014
7MP0004270_analgesia2.95207586
8MP0001968_abnormal_touch/_nociception2.87436773
9MP0002063_abnormal_learning/memory/cond2.80539224
10MP0005423_abnormal_somatic_nervous2.70822660
11MP0002572_abnormal_emotion/affect_behav2.60424828
12MP0006276_abnormal_autonomic_nervous2.54673244
13MP0002734_abnormal_mechanical_nocicepti2.51929539
14MP0009379_abnormal_foot_pigmentation2.51100956
15MP0001486_abnormal_startle_reflex2.46619212
16MP0002272_abnormal_nervous_system2.43073897
17MP0008877_abnormal_DNA_methylation2.42804453
18MP0002736_abnormal_nociception_after2.38698618
19MP0001440_abnormal_grooming_behavior2.27235528
20MP0000778_abnormal_nervous_system2.24186927
21MP0002067_abnormal_sensory_capabilities2.14460849
22MP0002735_abnormal_chemical_nociception2.13893710
23MP0004043_abnormal_pH_regulation1.95188514
24MP0004142_abnormal_muscle_tone1.91059308
25MP0002733_abnormal_thermal_nociception1.81665422
26MP0001188_hyperpigmentation1.81157301
27MP0004885_abnormal_endolymph1.81133322
28MP0001970_abnormal_pain_threshold1.79984864
29MP0003011_delayed_dark_adaptation1.75807134
30MP0005645_abnormal_hypothalamus_physiol1.72521376
31MP0003787_abnormal_imprinting1.69512449
32MP0001529_abnormal_vocalization1.68627387
33MP0002557_abnormal_social/conspecific_i1.66954242
34MP0005253_abnormal_eye_physiology1.62160653
35MP0008569_lethality_at_weaning1.61398804
36MP0003122_maternal_imprinting1.57810137
37MP0002184_abnormal_innervation1.57506245
38MP0001501_abnormal_sleep_pattern1.55759931
39MP0004924_abnormal_behavior1.47683900
40MP0005386_behavior/neurological_phenoty1.47683900
41MP0002102_abnormal_ear_morphology1.47577900
42MP0001905_abnormal_dopamine_level1.47055583
43MP0004742_abnormal_vestibular_system1.46694908
44MP0001986_abnormal_taste_sensitivity1.44447602
45MP0002066_abnormal_motor_capabilities/c1.43511868
46MP0005409_darkened_coat_color1.41592723
47MP0005646_abnormal_pituitary_gland1.39932498
48MP0001984_abnormal_olfaction1.37767268
49MP0002882_abnormal_neuron_morphology1.37709067
50MP0002638_abnormal_pupillary_reflex1.36765947
51MP0008789_abnormal_olfactory_epithelium1.36602703
52MP0000920_abnormal_myelination1.34974602
53MP0002822_catalepsy1.34742785
54MP0000955_abnormal_spinal_cord1.34227661
55MP0002876_abnormal_thyroid_physiology1.23684812
56MP0004811_abnormal_neuron_physiology1.21533391
57MP0005551_abnormal_eye_electrophysiolog1.19591011
58MP0002653_abnormal_ependyma_morphology1.19191851
59MP0004133_heterotaxia1.18108778
60MP0003329_amyloid_beta_deposits1.17948717
61MP0001485_abnormal_pinna_reflex1.15055483
62MP0003121_genomic_imprinting1.11938674
63MP0002751_abnormal_autonomic_nervous1.11348320
64MP0002152_abnormal_brain_morphology1.09113416
65MP0001963_abnormal_hearing_physiology1.06326693
66MP0000427_abnormal_hair_cycle1.05784103
67MP0001765_abnormal_ion_homeostasis1.05215821
68MP0003136_yellow_coat_color1.03878980
69MP0002229_neurodegeneration1.03249340
70MP0003938_abnormal_ear_development1.03161834
71MP0000631_abnormal_neuroendocrine_gland1.01790978
72MP0005195_abnormal_posterior_eye1.01516295
73MP0000049_abnormal_middle_ear1.01243000
74MP0004145_abnormal_muscle_electrophysio1.01220038
75MP0003890_abnormal_embryonic-extraembry1.00639824
76MP0003879_abnormal_hair_cell0.99974567
77MP0002069_abnormal_eating/drinking_beha0.97563168
78MP0001177_atelectasis0.97213201
79MP0009780_abnormal_chondrocyte_physiolo0.97090419
80MP0005174_abnormal_tail_pigmentation0.96798219
81MP0003119_abnormal_digestive_system0.96004034
82MP0002234_abnormal_pharynx_morphology0.95263618
83MP0000026_abnormal_inner_ear0.94415975
84MP0001502_abnormal_circadian_rhythm0.93211648
85MP0003634_abnormal_glial_cell0.92943565
86MP0003937_abnormal_limbs/digits/tail_de0.91813595
87MP0003646_muscle_fatigue0.91429300
88MP0002752_abnormal_somatic_nervous0.89779956
89MP0010386_abnormal_urinary_bladder0.88009907
90MP0005084_abnormal_gallbladder_morpholo0.87011858
91MP0005389_reproductive_system_phenotype0.85686290
92MP0000538_abnormal_urinary_bladder0.85331101
93MP0003633_abnormal_nervous_system0.83803185
94MP0002160_abnormal_reproductive_system0.82539790
95MP0005535_abnormal_body_temperature0.80885260
96MP0001958_emphysema0.80020682
97MP0005499_abnormal_olfactory_system0.78677959
98MP0005394_taste/olfaction_phenotype0.78677959
99MP0005187_abnormal_penis_morphology0.78241382
100MP0003690_abnormal_glial_cell0.77882695
101MP0005171_absent_coat_pigmentation0.76379387
102MP0002909_abnormal_adrenal_gland0.75561228
103MP0003195_calcinosis0.75083163
104MP0001293_anophthalmia0.74738913
105MP0004858_abnormal_nervous_system0.74426776
106MP0003283_abnormal_digestive_organ0.73847852
107MP0003631_nervous_system_phenotype0.73531342
108MP0005391_vision/eye_phenotype0.73383162
109MP0005379_endocrine/exocrine_gland_phen0.72363702
110MP0002163_abnormal_gland_morphology0.70047117
111MP0001943_abnormal_respiration0.68934176
112MP0000751_myopathy0.66981220
113MP0008872_abnormal_physiological_respon0.64384376
114MP0003861_abnormal_nervous_system0.64033195
115MP0002837_dystrophic_cardiac_calcinosis0.60877773
116MP0002082_postnatal_lethality0.60113310
117MP0010770_preweaning_lethality0.60113310
118MP0003137_abnormal_impulse_conducting0.59857588
119MP0006292_abnormal_olfactory_placode0.59822716
120MP0000569_abnormal_digit_pigmentation0.58474624
121MP0001664_abnormal_digestion0.58151894
122MP0001299_abnormal_eye_distance/0.57937630
123MP0010769_abnormal_survival0.57131336
124MP0005332_abnormal_amino_acid0.56622104
125MP0004215_abnormal_myocardial_fiber0.56574570
126MP0006072_abnormal_retinal_apoptosis0.56347904

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.47557821
2Increased circulating renin level (HP:0000848)4.50593199
3Hyperventilation (HP:0002883)4.49172254
4Atonic seizures (HP:0010819)4.34410398
5Focal seizures (HP:0007359)4.32931339
6Metabolic alkalosis (HP:0200114)4.23707580
7Hypomagnesemia (HP:0002917)4.13665903
8Progressive cerebellar ataxia (HP:0002073)3.77106096
9Epileptic encephalopathy (HP:0200134)3.74825185
10Absence seizures (HP:0002121)3.72915004
11Myokymia (HP:0002411)3.66585429
12Broad-based gait (HP:0002136)3.64691456
13Hypokalemic alkalosis (HP:0001949)3.50735419
14Visual hallucinations (HP:0002367)3.43010136
15Dialeptic seizures (HP:0011146)3.40681552
16Febrile seizures (HP:0002373)3.35667742
17Nephronophthisis (HP:0000090)3.32518290
18True hermaphroditism (HP:0010459)3.31464021
19Abnormality of magnesium homeostasis (HP:0004921)3.30662036
20Congenital stationary night blindness (HP:0007642)3.27904539
21Molar tooth sign on MRI (HP:0002419)3.26301843
22Abnormality of midbrain morphology (HP:0002418)3.26301843
23Hyperactive renin-angiotensin system (HP:0000841)3.23101010
24Pancreatic cysts (HP:0001737)3.23076981
25Polyphagia (HP:0002591)3.22525447
26Pancreatic fibrosis (HP:0100732)3.08675344
27Polyuria (HP:0000103)3.07946286
28Volvulus (HP:0002580)3.04667928
29Fetal akinesia sequence (HP:0001989)2.99691768
30Abnormal eating behavior (HP:0100738)2.97316932
31Type II lissencephaly (HP:0007260)2.95398024
32Generalized tonic-clonic seizures (HP:0002069)2.91046381
33Abnormal drinking behavior (HP:0030082)2.83335065
34Polydipsia (HP:0001959)2.83335065
35Drooling (HP:0002307)2.83020619
36Excessive salivation (HP:0003781)2.83020619
37Abnormality of the renal medulla (HP:0100957)2.81979087
38Abnormality of chloride homeostasis (HP:0011422)2.81901852
39Abnormality of renin-angiotensin system (HP:0000847)2.80820150
40Abnormal urine output (HP:0012590)2.75541351
41Progressive inability to walk (HP:0002505)2.68727537
42Abnormality of the renal cortex (HP:0011035)2.67200456
43Abolished electroretinogram (ERG) (HP:0000550)2.59209807
44Gaze-evoked nystagmus (HP:0000640)2.57974140
45Intestinal atresia (HP:0011100)2.53430722
46Hyperaldosteronism (HP:0000859)2.51474017
47Oligodactyly (hands) (HP:0001180)2.50472890
48Hyperphosphaturia (HP:0003109)2.49952327
49Supranuclear gaze palsy (HP:0000605)2.48662110
50Abnormality of renal excretion (HP:0011036)2.47873264
51Optic nerve hypoplasia (HP:0000609)2.46818458
52Mutism (HP:0002300)2.44805145
53Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.42285401
54Anxiety (HP:0000739)2.38684562
55Dysmetria (HP:0001310)2.37523897
56Renal cortical cysts (HP:0000803)2.37066189
57Agitation (HP:0000713)2.36868937
58Mitochondrial inheritance (HP:0001427)2.36243495
59Sleep apnea (HP:0010535)2.35757291
60Congenital primary aphakia (HP:0007707)2.35477239
61Gout (HP:0001997)2.34364974
62Septo-optic dysplasia (HP:0100842)2.31368736
63Ankle clonus (HP:0011448)2.29187523
64Obstructive sleep apnea (HP:0002870)2.28450268
65Blue irides (HP:0000635)2.27945797
66Akinesia (HP:0002304)2.27563246
67Progressive macrocephaly (HP:0004481)2.27186102
68Abnormal rod and cone electroretinograms (HP:0008323)2.27126951
69Neurofibrillary tangles (HP:0002185)2.24704745
70Acute necrotizing encephalopathy (HP:0006965)2.24369605
71Tetany (HP:0001281)2.21635326
72Absent speech (HP:0001344)2.20981612
73Protruding tongue (HP:0010808)2.18751168
74Retinal dysplasia (HP:0007973)2.18639645
75Abnormal urine phosphate concentration (HP:0012599)2.18587955
76Abnormality of the labia minora (HP:0012880)2.17014654
77Dysdiadochokinesis (HP:0002075)2.16627509
78Aplasia/Hypoplasia of the tibia (HP:0005772)2.16467533
79Aplasia/Hypoplasia of the spleen (HP:0010451)2.14888588
80Dyskinesia (HP:0100660)2.14210978
81Truncal ataxia (HP:0002078)2.13968912
82Increased hepatocellular lipid droplets (HP:0006565)2.13856122
83Chronic hepatic failure (HP:0100626)2.12274869
84Gait imbalance (HP:0002141)2.12075805
85Abnormality of the corticospinal tract (HP:0002492)2.11625396
86Pendular nystagmus (HP:0012043)2.10801255
87Abnormality of renal resorption (HP:0011038)2.10401070
88Papilledema (HP:0001085)2.10201133
89Pachygyria (HP:0001302)2.09691240
90Genital tract atresia (HP:0001827)2.09496198
91Genetic anticipation (HP:0003743)2.09113621
92Lissencephaly (HP:0001339)2.08076354
93Abnormality of salivation (HP:0100755)2.07838900
94Acute encephalopathy (HP:0006846)2.07575543
95Inability to walk (HP:0002540)2.07476971
96Hyperthyroidism (HP:0000836)2.07444055
97Renal salt wasting (HP:0000127)2.05758961
98Hepatocellular necrosis (HP:0001404)2.05616255
99Hemiparesis (HP:0001269)2.04630425
100Degeneration of the lateral corticospinal tracts (HP:0002314)2.04620036
101Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.04620036
102Abnormal mitochondria in muscle tissue (HP:0008316)2.04225952
103Short tibia (HP:0005736)2.04111666
104Vaginal atresia (HP:0000148)2.02678514
105Poor eye contact (HP:0000817)2.01912051
106Renal Fanconi syndrome (HP:0001994)1.99910267
107Specific learning disability (HP:0001328)1.99588351
108Absent rod-and cone-mediated responses on ERG (HP:0007688)1.98275007
109Thickened helices (HP:0000391)1.96576085
110Abnormality of binocular vision (HP:0011514)1.96141923
111Diplopia (HP:0000651)1.96141923
112Sclerocornea (HP:0000647)1.95181966
113Stomach cancer (HP:0012126)1.95108296
114Cystic liver disease (HP:0006706)1.94982208
115Humeroradial synostosis (HP:0003041)1.93976743
116Synostosis involving the elbow (HP:0003938)1.93976743
117Action tremor (HP:0002345)1.92865563
118Oligodactyly (HP:0012165)1.92269197
119Postaxial foot polydactyly (HP:0001830)1.91921537
120Medial flaring of the eyebrow (HP:0010747)1.91828393
121Hemiplegia (HP:0002301)1.91269673
122Peripheral hypomyelination (HP:0007182)1.91253536
123Depression (HP:0000716)1.90861108
124Alkalosis (HP:0001948)1.90197855
125Abnormality of the middle phalanges of the toes (HP:0010183)1.89697127
126Asplenia (HP:0001746)1.89576663
127Epileptiform EEG discharges (HP:0011182)1.89341238
128Aplasia/Hypoplasia of the sternum (HP:0006714)1.89301604
129Amblyopia (HP:0000646)1.88739133
130Generalized myoclonic seizures (HP:0002123)1.88447849
131Increased corneal curvature (HP:0100692)1.85775788
132Keratoconus (HP:0000563)1.85775788
133Nephrogenic diabetes insipidus (HP:0009806)1.85287723
134Ectopic kidney (HP:0000086)1.84397615
135Megalencephaly (HP:0001355)1.84096693
136Partial agenesis of the corpus callosum (HP:0001338)1.83659681
137Bony spicule pigmentary retinopathy (HP:0007737)1.82911931
138EEG with generalized epileptiform discharges (HP:0011198)1.82805141
139Pheochromocytoma (HP:0002666)1.82164887
140Limb dystonia (HP:0002451)1.81420250
141Postaxial hand polydactyly (HP:0001162)1.80928478
142Methylmalonic acidemia (HP:0002912)1.80699474
143Abnormal social behavior (HP:0012433)1.80087834
144Impaired social interactions (HP:0000735)1.80087834
145Abnormal hair whorl (HP:0010721)1.79345840
146Gastrointestinal atresia (HP:0002589)1.79138571
147Status epilepticus (HP:0002133)1.78962453
148Cerebral inclusion bodies (HP:0100314)1.77138683
149Abnormality of glycolysis (HP:0004366)1.76800272
150Anencephaly (HP:0002323)1.75917185
151Attenuation of retinal blood vessels (HP:0007843)1.74433236
152Male pseudohermaphroditism (HP:0000037)1.73940832
153IgG deficiency (HP:0004315)1.73728824
154Hypothermia (HP:0002045)1.71518082
155Cerebellar dysplasia (HP:0007033)1.70215732
156Amyotrophic lateral sclerosis (HP:0007354)1.70126958
157Increased CSF lactate (HP:0002490)1.67386596
158Morphological abnormality of the pyramidal tract (HP:0002062)1.65598000
1593-Methylglutaconic aciduria (HP:0003535)1.65067055
160Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.63970891

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK3.58485263
2MARK13.44712508
3OXSR13.43574756
4WNK43.21910046
5NTRK33.14818762
6WNK33.14217549
7STK393.00997787
8MAP2K72.86609536
9FRK2.74546273
10MAP3K42.59999762
11TNIK2.42371447
12TAOK32.35531991
13MAP4K22.29795403
14EPHA42.24163198
15MAP3K122.18311526
16MINK12.11971774
17PINK12.11076797
18ADRBK22.04671900
19GRK12.03891904
20PNCK2.01439650
21ACVR1B1.99852583
22MAPK131.89329262
23NME11.89291652
24MAP3K91.87628054
25NTRK21.82164170
26NUAK11.79893581
27CDK191.69303532
28FES1.66287378
29TXK1.63131827
30ZAK1.57420323
31PLK21.43621020
32KSR11.42184254
33PAK61.39240550
34BCR1.35639125
35UHMK11.34584657
36SIK21.32249287
37INSRR1.31846868
38MAP2K41.30313492
39DAPK21.23036073
40CDK51.22758865
41RIPK41.21345589
42PRKD31.19943865
43TRIM281.15293914
44SGK4941.11980263
45SGK2231.11980263
46MAP2K21.10661414
47DYRK1A1.06268925
48FGR1.03975815
49GRK71.03836510
50TLK11.02591827
51CAMK2A1.02209902
52STK381.00276733
53PKN10.99585426
54PRKCG0.97746634
55WNK10.95483627
56GRK50.93131223
57NTRK10.89203483
58CAMK2B0.87141163
59DYRK20.84288804
60STK110.82013014
61CDK140.79771109
62PLK40.78690160
63CSNK1G20.78521983
64IRAK20.76873917
65PRPF4B0.76870202
66CAMKK20.75315534
67CDK180.74495852
68MST40.74413708
69PAK30.74365884
70WEE10.73943392
71NEK60.73713136
72MAP3K130.73150904
73DMPK0.72582668
74LMTK20.70660586
75CDK150.70566894
76AKT30.70084079
77KSR20.68368298
78BMPR20.67305220
79PRKCE0.66986417
80PHKG10.66707694
81PHKG20.66707694
82LATS20.64586741
83MKNK20.64232139
84SGK10.63026077
85CDK11A0.62350339
86NLK0.59622599
87SGK20.59305581
88ROCK20.58715551
89CAMK2D0.57506613
90CSNK1G30.57307844
91CCNB10.52347713
92PRKCQ0.52026656
93TYRO30.51689753
94ADRBK10.50847435
95FGFR20.49355206
96CAMK10.48488377
97CAMK2G0.47994585
98VRK10.47969787
99EIF2AK20.47339487
100PTK2B0.47181845
101FER0.47112663
102BMPR1B0.46014763
103CSNK1G10.44542957
104MAP2K10.44533944
105PLK30.43805206
106MAPKAPK50.43582233
107BUB10.43506379
108FYN0.43264882
109SIK30.42968460
110EPHA30.42334442
111PRKCZ0.41995327
112CSNK1D0.40330903
113TIE10.40271709
114CDK30.39254744
115MAP3K20.39056132
116BCKDK0.38939939
117PRKACA0.38627926
118DAPK10.37037403
119RAF10.36741521
120ERBB40.36474635
121STK160.36450427
122MAPK150.36286813
123MUSK0.35475645
124PRKCH0.33709847
125PRKCA0.33293844
126ERBB30.32893979
127MARK20.32745163
128IRAK10.32689852
129MAP3K60.31797012
130CSNK1A10.31577455
131SGK30.31330737
132PRKG10.31194083
133CSNK1A1L0.31008554
134PIK3CA0.30992657
135EIF2AK10.30578819
136RPS6KA30.30403963
137TGFBR10.30342745
138ROCK10.30055801
139ERBB20.29752646
140RPS6KA50.29030684
141CAMK40.28826897

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.16879520
2Synaptic vesicle cycle_Homo sapiens_hsa047213.19944945
3Collecting duct acid secretion_Homo sapiens_hsa049662.93442462
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.76187940
5GABAergic synapse_Homo sapiens_hsa047272.75616924
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.49547262
7Oxidative phosphorylation_Homo sapiens_hsa001902.48493440
8Glutamatergic synapse_Homo sapiens_hsa047242.48418085
9Morphine addiction_Homo sapiens_hsa050322.33405665
10Long-term potentiation_Homo sapiens_hsa047202.26156719
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.26029049
12Circadian entrainment_Homo sapiens_hsa047132.15736368
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.99835735
14Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.98291163
15Serotonergic synapse_Homo sapiens_hsa047261.97313442
16Amphetamine addiction_Homo sapiens_hsa050311.93180537
17Long-term depression_Homo sapiens_hsa047301.86394468
18Parkinsons disease_Homo sapiens_hsa050121.84374662
19Gastric acid secretion_Homo sapiens_hsa049711.82783601
20Dopaminergic synapse_Homo sapiens_hsa047281.81808727
21Olfactory transduction_Homo sapiens_hsa047401.78944255
22Salivary secretion_Homo sapiens_hsa049701.78840391
23Taste transduction_Homo sapiens_hsa047421.72207666
24Cardiac muscle contraction_Homo sapiens_hsa042601.69980266
25Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.67599497
26Alzheimers disease_Homo sapiens_hsa050101.66176252
27Renin secretion_Homo sapiens_hsa049241.63524344
28Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.59059810
29Vibrio cholerae infection_Homo sapiens_hsa051101.57589601
30Axon guidance_Homo sapiens_hsa043601.57180760
31Caffeine metabolism_Homo sapiens_hsa002321.54455759
32Cholinergic synapse_Homo sapiens_hsa047251.53980759
33Butanoate metabolism_Homo sapiens_hsa006501.51942823
34Nitrogen metabolism_Homo sapiens_hsa009101.46924401
35Insulin secretion_Homo sapiens_hsa049111.46868365
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.40337559
37Protein export_Homo sapiens_hsa030601.40138175
38Basal transcription factors_Homo sapiens_hsa030221.39914978
39Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.39411727
40Calcium signaling pathway_Homo sapiens_hsa040201.33800338
41Linoleic acid metabolism_Homo sapiens_hsa005911.29251616
42Cocaine addiction_Homo sapiens_hsa050301.28366195
43Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.27365697
44Tryptophan metabolism_Homo sapiens_hsa003801.26018940
45Oxytocin signaling pathway_Homo sapiens_hsa049211.25094127
46Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.23583821
47Fanconi anemia pathway_Homo sapiens_hsa034601.23481999
48Huntingtons disease_Homo sapiens_hsa050161.22094299
49Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.21584239
50Aldosterone synthesis and secretion_Homo sapiens_hsa049251.18298016
51Gap junction_Homo sapiens_hsa045401.18098836
52Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.17970593
53Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.15164629
54ErbB signaling pathway_Homo sapiens_hsa040121.12250014
55Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.10208180
56alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.06380166
57Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.04574121
58RNA degradation_Homo sapiens_hsa030181.03151471
59Phototransduction_Homo sapiens_hsa047441.02567682
60Cyanoamino acid metabolism_Homo sapiens_hsa004601.02486149
61Maturity onset diabetes of the young_Homo sapiens_hsa049500.99649393
62Propanoate metabolism_Homo sapiens_hsa006400.95006036
63cAMP signaling pathway_Homo sapiens_hsa040240.92693363
64GnRH signaling pathway_Homo sapiens_hsa049120.92498519
65Glioma_Homo sapiens_hsa052140.88584864
66RNA polymerase_Homo sapiens_hsa030200.86057572
67Homologous recombination_Homo sapiens_hsa034400.85188801
68Regulation of autophagy_Homo sapiens_hsa041400.85159177
69Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.84539575
70Choline metabolism in cancer_Homo sapiens_hsa052310.84228986
71Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.82078632
72Peroxisome_Homo sapiens_hsa041460.81734465
73Phosphatidylinositol signaling system_Homo sapiens_hsa040700.80471343
74Selenocompound metabolism_Homo sapiens_hsa004500.76555998
75Estrogen signaling pathway_Homo sapiens_hsa049150.74391899
76Melanogenesis_Homo sapiens_hsa049160.74034308
77Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.73727543
78Retinol metabolism_Homo sapiens_hsa008300.73626318
79Chemical carcinogenesis_Homo sapiens_hsa052040.73016454
80Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.71389279
81beta-Alanine metabolism_Homo sapiens_hsa004100.70729234
82Primary bile acid biosynthesis_Homo sapiens_hsa001200.70701107
83Pancreatic secretion_Homo sapiens_hsa049720.68276505
84Circadian rhythm_Homo sapiens_hsa047100.66727034
85Phospholipase D signaling pathway_Homo sapiens_hsa040720.66673383
86Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.65239032
87Rheumatoid arthritis_Homo sapiens_hsa053230.64668802
88Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.63454941
89Vascular smooth muscle contraction_Homo sapiens_hsa042700.62532762
90Hedgehog signaling pathway_Homo sapiens_hsa043400.62399916
91Steroid biosynthesis_Homo sapiens_hsa001000.61552739
92Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.61427380
93Renal cell carcinoma_Homo sapiens_hsa052110.61092767
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61092445
95Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61086657
96Oocyte meiosis_Homo sapiens_hsa041140.61056095
97cGMP-PKG signaling pathway_Homo sapiens_hsa040220.59302621
98Thyroid hormone synthesis_Homo sapiens_hsa049180.58736030
99ABC transporters_Homo sapiens_hsa020100.55174805
100Glycerolipid metabolism_Homo sapiens_hsa005610.54936808
101Ras signaling pathway_Homo sapiens_hsa040140.54760018
102Dorso-ventral axis formation_Homo sapiens_hsa043200.54572496
103Ovarian steroidogenesis_Homo sapiens_hsa049130.54308809
104Vitamin B6 metabolism_Homo sapiens_hsa007500.54273991
105Steroid hormone biosynthesis_Homo sapiens_hsa001400.53965545
106MAPK signaling pathway_Homo sapiens_hsa040100.49840125
107Type II diabetes mellitus_Homo sapiens_hsa049300.49342929
108Alcoholism_Homo sapiens_hsa050340.48704928
109Inositol phosphate metabolism_Homo sapiens_hsa005620.48619339
110Sphingolipid signaling pathway_Homo sapiens_hsa040710.48603623
111Folate biosynthesis_Homo sapiens_hsa007900.48187073
112Sphingolipid metabolism_Homo sapiens_hsa006000.47434424
113Phagosome_Homo sapiens_hsa041450.46720829
114Histidine metabolism_Homo sapiens_hsa003400.46093506
115Ether lipid metabolism_Homo sapiens_hsa005650.45425820
116Purine metabolism_Homo sapiens_hsa002300.44131787
117Wnt signaling pathway_Homo sapiens_hsa043100.43666757
118Basal cell carcinoma_Homo sapiens_hsa052170.42252366
119Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.40013986
120Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.38952447
121Dilated cardiomyopathy_Homo sapiens_hsa054140.38597990
122Fatty acid metabolism_Homo sapiens_hsa012120.38537883
123Arachidonic acid metabolism_Homo sapiens_hsa005900.38531789
124Sulfur metabolism_Homo sapiens_hsa009200.37971887
125* Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37900534
126Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.35359061
127Fatty acid elongation_Homo sapiens_hsa000620.34759115
128Mineral absorption_Homo sapiens_hsa049780.34562947
129Rap1 signaling pathway_Homo sapiens_hsa040150.34315818
130Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.31837435
131Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.31052969
132Melanoma_Homo sapiens_hsa052180.30426578
133Endocytosis_Homo sapiens_hsa041440.30373673
134Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.30262965
135Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.27387586
136Endometrial cancer_Homo sapiens_hsa052130.26203505
137Bile secretion_Homo sapiens_hsa049760.24823162
138Carbohydrate digestion and absorption_Homo sapiens_hsa049730.21829388
139Pyruvate metabolism_Homo sapiens_hsa006200.21625912
140Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.19028391
141Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.16103198
142Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.15541378
143VEGF signaling pathway_Homo sapiens_hsa043700.14983863

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