B3GNT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. Two transcript variants encoding the same protein have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)6.21721436
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.75333144
3antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.75333144
4antigen processing and presentation of endogenous antigen (GO:0019883)5.04782459
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.95547543
6regulation of gamma-delta T cell differentiation (GO:0045586)4.72594530
7positive regulation of B cell differentiation (GO:0045579)4.64768960
8regulation of gamma-delta T cell activation (GO:0046643)4.53002526
9modulation by symbiont of host defense response (GO:0052031)4.45782038
10modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.45782038
11modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.45782038
12positive regulation by organism of defense response of other organism involved in symbiotic interact4.45782038
13modulation by symbiont of host immune response (GO:0052553)4.45782038
14positive regulation by symbiont of host defense response (GO:0052509)4.45782038
15regulation of histone H3-K9 methylation (GO:0051570)4.35165437
16regulation of interleukin-12 biosynthetic process (GO:0045075)4.34912926
17neutrophil activation involved in immune response (GO:0002283)4.21508327
18regulation of DNA methylation (GO:0044030)4.10086853
19immunoglobulin mediated immune response (GO:0016064)4.01523136
20positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.95048744
21positive regulation of humoral immune response (GO:0002922)3.94399467
22B cell receptor signaling pathway (GO:0050853)3.93603302
23respiratory burst (GO:0045730)3.84895858
24regulation of female gonad development (GO:2000194)3.81420679
25regulation of B cell receptor signaling pathway (GO:0050855)3.78405817
26negative regulation of cell killing (GO:0031342)3.76707045
27negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.76707045
28mast cell activation (GO:0045576)3.75170417
29regulation of B cell differentiation (GO:0045577)3.73094984
30response to protozoan (GO:0001562)3.68879075
31regulation of interferon-beta biosynthetic process (GO:0045357)3.67110030
32defense response to protozoan (GO:0042832)3.66664202
33neutrophil activation (GO:0042119)3.62979652
34cellular extravasation (GO:0045123)3.55701872
35leukocyte aggregation (GO:0070486)3.54610026
36T cell migration (GO:0072678)3.48541777
37granulocyte activation (GO:0036230)3.44513608
38macrophage activation involved in immune response (GO:0002281)3.43548767
39myeloid cell activation involved in immune response (GO:0002275)3.34498138
40response to muramyl dipeptide (GO:0032495)3.26761713
41positive regulation of isotype switching (GO:0045830)3.26133349
42positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.25971696
43cellular response to arsenic-containing substance (GO:0071243)3.23719485
44positive regulation of interferon-alpha production (GO:0032727)3.21108199
45myeloid dendritic cell activation (GO:0001773)3.20916399
46tolerance induction (GO:0002507)3.20485368
47natural killer cell differentiation (GO:0001779)3.15856111
48mast cell activation involved in immune response (GO:0002279)3.12805596
49mast cell degranulation (GO:0043303)3.12805596
50myeloid dendritic cell differentiation (GO:0043011)3.12663565
51interferon-gamma-mediated signaling pathway (GO:0060333)3.12116428
52regulation of interferon-alpha production (GO:0032647)3.11771795
53JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.09934916
54response to type I interferon (GO:0034340)3.09037369
55positive regulation of mitotic sister chromatid separation (GO:1901970)3.06581240
56positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.06581240
57positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.06581240
58negative regulation of phagocytosis (GO:0050765)3.05906961
59T cell homeostasis (GO:0043029)3.05606918
60response to interleukin-15 (GO:0070672)3.05537997
61cellular response to type I interferon (GO:0071357)3.04612452
62type I interferon signaling pathway (GO:0060337)3.04612452
63regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.04178098
64response to host immune response (GO:0052572)3.03929154
65response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.03929154
66B cell mediated immunity (GO:0019724)3.03850328
67positive regulation of histone H3-K4 methylation (GO:0051571)3.02769558
68protein localization to chromosome, centromeric region (GO:0071459)3.02067292
69interferon-gamma production (GO:0032609)3.00829979
70regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.99751321
71positive regulation of B cell mediated immunity (GO:0002714)2.96571466
72positive regulation of immunoglobulin mediated immune response (GO:0002891)2.96571466
73response to host (GO:0075136)2.96333762
74response to host defenses (GO:0052200)2.96333762
75response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.96333762
76NIK/NF-kappaB signaling (GO:0038061)2.94529507
77negative regulation of histone methylation (GO:0031061)2.94090471
78negative regulation of interleukin-12 production (GO:0032695)2.93157294
79regulation of hypersensitivity (GO:0002883)2.92368092
80positive regulation of natural killer cell differentiation (GO:0032825)2.91011810
81Arp2/3 complex-mediated actin nucleation (GO:0034314)2.90907273
82positive thymic T cell selection (GO:0045059)2.89808348
83positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.89158710
84response to peptidoglycan (GO:0032494)2.86285122
85mature B cell differentiation (GO:0002335)2.85481518
86negative T cell selection (GO:0043383)2.85071342
87regulation of T cell receptor signaling pathway (GO:0050856)2.84747390
88negative thymic T cell selection (GO:0045060)2.84280604
89leukocyte degranulation (GO:0043299)2.82108951
90regulation of T-helper 1 cell differentiation (GO:0045625)2.81643802
91regulation of alpha-beta T cell proliferation (GO:0046640)2.81524160
92regulation of meiosis I (GO:0060631)2.80602655
93regulation of vitamin D biosynthetic process (GO:0060556)2.79479950
94myeloid leukocyte activation (GO:0002274)2.79008944
95lymphocyte homeostasis (GO:0002260)2.77962185
96hepatocyte apoptotic process (GO:0097284)2.77652778
97positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.77509050
98leukocyte cell-cell adhesion (GO:0007159)2.75175045
99regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.74783810
100pinocytosis (GO:0006907)2.74242286
101T-helper 1 type immune response (GO:0042088)2.74135790
102antigen receptor-mediated signaling pathway (GO:0050851)2.72577952
103positive regulation of interleukin-2 production (GO:0032743)2.72354285
104positive regulation of cytokine biosynthetic process (GO:0042108)2.72085585
105establishment of chromosome localization (GO:0051303)2.70124944
106regulation of interleukin-2 biosynthetic process (GO:0045076)2.69293725
107meiotic cell cycle (GO:0051321)2.66639929
108lipopolysaccharide-mediated signaling pathway (GO:0031663)2.65422914
109antigen processing and presentation via MHC class Ib (GO:0002475)2.64822037
110mature B cell differentiation involved in immune response (GO:0002313)2.63984212
111mitotic chromosome condensation (GO:0007076)2.63646374
112natural killer cell activation (GO:0030101)2.63390154
113positive regulation of DNA recombination (GO:0045911)2.63177135
114protein kinase C signaling (GO:0070528)2.62703322
115regulation of type I interferon-mediated signaling pathway (GO:0060338)2.62687667
116positive regulation of interferon-beta production (GO:0032728)2.62370874
117positive regulation of chromosome segregation (GO:0051984)2.61770468
118negative regulation of erythrocyte differentiation (GO:0045647)2.61291751
119negative regulation of interleukin-17 production (GO:0032700)2.61263167
120CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.61235657
121positive regulation of alpha-beta T cell proliferation (GO:0046641)2.60159634
122cellular response to interleukin-15 (GO:0071350)2.59357538
123dendritic cell differentiation (GO:0097028)2.58500122
124protein localization to kinetochore (GO:0034501)2.58461534
125detection of other organism (GO:0098543)2.58341199
126positive regulation of immunoglobulin production (GO:0002639)2.58076217
127viral transcription (GO:0019083)2.57811738
128germinal center formation (GO:0002467)2.57450575
129positive regulation of B cell activation (GO:0050871)2.57044073
130detection of bacterium (GO:0016045)2.51831346
131mitotic metaphase plate congression (GO:0007080)2.44557777
132nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.43188972
133B cell proliferation (GO:0042100)2.42969650
134regulation of chromatin silencing (GO:0031935)2.40645666
135regulation of dendritic cell antigen processing and presentation (GO:0002604)2.40325993
136B cell homeostasis (GO:0001782)2.38404673
137oocyte development (GO:0048599)2.38131988
138negative regulation of myeloid cell apoptotic process (GO:0033033)2.37700088
139T cell lineage commitment (GO:0002360)2.37619203
140positive regulation of B cell proliferation (GO:0030890)2.36824977
141piRNA metabolic process (GO:0034587)2.35411242
142regulation of vitamin metabolic process (GO:0030656)2.34014338
143regulation of interleukin-12 production (GO:0032655)2.33986648
144regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.32201297
145cellular response to thyroid hormone stimulus (GO:0097067)2.31892857
146regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.29965952
147positive regulation of interleukin-10 production (GO:0032733)2.29759263
148regulation of interferon-beta production (GO:0032648)2.29627567
149female gamete generation (GO:0007292)2.28527427

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.59419397
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.52499844
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.23747798
4IRF8_21731497_ChIP-ChIP_J774_Mouse3.81152415
5* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.63694120
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.59116220
7* IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.55213421
8E2F7_22180533_ChIP-Seq_HELA_Human3.34273396
9MYB_21317192_ChIP-Seq_ERMYB_Mouse3.29039697
10MYC_22102868_ChIP-Seq_BL_Human3.18987072
11SCL_19346495_ChIP-Seq_HPC-7_Human3.04411313
12BP1_19119308_ChIP-ChIP_Hs578T_Human2.95367620
13SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.93405710
14* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.92796609
15* VDR_21846776_ChIP-Seq_THP-1_Human2.86182851
16IRF8_27001747_Chip-Seq_BMDM_Mouse2.80893268
17IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.78853512
18NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.78827337
19STAT4_19710469_ChIP-ChIP_TH1__Mouse2.72978174
20STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.70140136
21MYB_26560356_Chip-Seq_TH2_Human2.50523308
22NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.50067673
23RUNX_20019798_ChIP-Seq_JUKART_Human2.49305575
24FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.37204396
25MAF_26560356_Chip-Seq_TH1_Human2.36634359
26KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.35837427
27KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.35837427
28KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.35837427
29SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.33317809
30* VDR_24763502_ChIP-Seq_THP-1_Human2.28539524
31* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.27806265
32MYB_26560356_Chip-Seq_TH1_Human2.26884630
33SPI1_23547873_ChIP-Seq_NB4_Human2.21689769
34BRD4_27068464_Chip-Seq_AML-cells_Mouse2.20836786
35BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.17806811
36RUNX1_22412390_ChIP-Seq_EML_Mouse2.14136468
37FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.12678637
38UTX_26944678_Chip-Seq_JUKART_Human2.09461992
39RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.04919414
40* TCF7_22412390_ChIP-Seq_EML_Mouse1.99680527
41ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.92593225
42NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.92585143
43GATA1_22025678_ChIP-Seq_K562_Human1.87594580
44E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.84839717
45FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.75885289
46MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.69446475
47TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.67983723
48STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.66832874
49NOTCH1_21737748_ChIP-Seq_TLL_Human1.65047660
50FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.63102711
51E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.60890992
52KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.60569799
53SPI1_23127762_ChIP-Seq_K562_Human1.59793331
54SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.56477687
55* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.53721580
56TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.52059687
57GATA3_27048872_Chip-Seq_THYMUS_Human1.49718065
58MAF_26560356_Chip-Seq_TH2_Human1.47442068
59GATA2_22383799_ChIP-Seq_G1ME_Mouse1.46949482
60KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.44526100
61PU_27001747_Chip-Seq_BMDM_Mouse1.43819105
62MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.43571273
63SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.41597949
64FOXM1_23109430_ChIP-Seq_U2OS_Human1.40673342
65* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.40316075
66GATA1_22383799_ChIP-Seq_G1ME_Mouse1.40011289
67EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.38446691
68ELK3_25401928_ChIP-Seq_HUVEC_Human1.37290103
69* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.36867665
70NELFA_20434984_ChIP-Seq_ESCs_Mouse1.35600039
71KDM2B_26808549_Chip-Seq_DND41_Human1.32763837
72CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.27850054
73MYC_18555785_ChIP-Seq_MESCs_Mouse1.24664421
74TP63_17297297_ChIP-ChIP_HaCaT_Human1.23494273
75ERG_20887958_ChIP-Seq_HPC-7_Mouse1.23179600
76CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20396275
77* LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.19192115
78SMAD_19615063_ChIP-ChIP_OVARY_Human1.16050499
79HOXB4_20404135_ChIP-ChIP_EML_Mouse1.15215261
80* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14222331
81* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.13563450
82GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.11551500
83NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.11483657
84* MYC_19079543_ChIP-ChIP_MESCs_Mouse1.10778308
85* GATA3_26560356_Chip-Seq_TH2_Human1.09666757
86* VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.08951143
87GATA1_19941827_ChIP-Seq_MEL_Mouse1.08007392
88* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.06775990
89FOXP3_21729870_ChIP-Seq_TREG_Human1.04501979
90STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.02956907
91CREB1_15753290_ChIP-ChIP_HEK293T_Human1.01960199
92AR_21909140_ChIP-Seq_LNCAP_Human1.00514218
93* MYC_19030024_ChIP-ChIP_MESCs_Mouse0.99535421
94GATA2_21666600_ChIP-Seq_HMVEC_Human0.99011606
95E2F4_17652178_ChIP-ChIP_JURKAT_Human0.98876554
96CIITA_25753668_ChIP-Seq_RAJI_Human0.97172209
97* PU.1_20513432_ChIP-Seq_Bcells_Mouse0.94507021
98TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94323926
99TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.93609214
100NCOR1_26117541_ChIP-Seq_K562_Human0.93562327
101* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93065469
102* VDR_24787735_ChIP-Seq_THP-1_Human0.89415314
103* GATA1_19941826_ChIP-Seq_K562_Human0.88787192
104PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.87729320
105* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86052550
106PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.85602522
107IRF1_19129219_ChIP-ChIP_H3396_Human0.85277071
108* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.82840476
109SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.81612974
110ZFX_18555785_ChIP-Seq_MESCs_Mouse0.81449959
111E2F1_21310950_ChIP-Seq_MCF-7_Human0.80992885
112KDM2B_26808549_Chip-Seq_JURKAT_Human0.80759206
113* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.80083787
114* MYC_18358816_ChIP-ChIP_MESCs_Mouse0.80071384
115ELF1_17652178_ChIP-ChIP_JURKAT_Human0.78764215
116* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.78724565
117RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.78616959
118* GATA2_19941826_ChIP-Seq_K562_Human0.77904918
119TFEB_21752829_ChIP-Seq_HELA_Human0.77100730
120VDR_23849224_ChIP-Seq_CD4+_Human0.76577659
121ETS1_22383799_ChIP-Seq_G1ME_Mouse0.76472462
122MYCN_18555785_ChIP-Seq_MESCs_Mouse0.76369344
123* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74895810
124KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.73695175
125* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.73422607

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.89886661
2MP0003303_peritoneal_inflammation3.39341380
3MP0003436_decreased_susceptibility_to3.30442803
4MP0000685_abnormal_immune_system3.17868092
5MP0009785_altered_susceptibility_to3.10229839
6MP0001800_abnormal_humoral_immune3.06728804
7MP0003718_maternal_effect3.06662670
8MP0005671_abnormal_response_to2.93497438
9MP0005000_abnormal_immune_tolerance2.91890358
10MP0005387_immune_system_phenotype2.91083330
11MP0001790_abnormal_immune_system2.91083330
12* MP0002452_abnormal_antigen_presenting2.74964690
13MP0002139_abnormal_hepatobiliary_system2.67206076
14* MP0002723_abnormal_immune_serum2.62941801
15MP0005025_abnormal_response_to2.60421509
16* MP0002419_abnormal_innate_immunity2.59838539
17* MP0002420_abnormal_adaptive_immunity2.54151897
18MP0003300_gastrointestinal_ulcer2.53860277
19* MP0001819_abnormal_immune_cell2.51153826
20MP0005464_abnormal_platelet_physiology2.48206822
21MP0002138_abnormal_hepatobiliary_system2.46646511
22MP0003763_abnormal_thymus_physiology2.43231782
23MP0002396_abnormal_hematopoietic_system2.36723047
24* MP0002398_abnormal_bone_marrow2.36239942
25MP0002148_abnormal_hypersensitivity_rea2.31918187
26MP0003724_increased_susceptibility_to2.31836171
27MP0002166_altered_tumor_susceptibility2.22964307
28MP0002405_respiratory_system_inflammati2.19231447
29* MP0000716_abnormal_immune_system2.14968519
30MP0006082_CNS_inflammation2.13603343
31MP0005397_hematopoietic_system_phenotyp2.12237247
32MP0001545_abnormal_hematopoietic_system2.12237247
33MP0009278_abnormal_bone_marrow2.09814822
34MP0000689_abnormal_spleen_morphology2.05441123
35MP0010155_abnormal_intestine_physiology2.03909188
36MP0001873_stomach_inflammation1.97932390
37MP0002722_abnormal_immune_system1.95680026
38MP0009333_abnormal_splenocyte_physiolog1.95057249
39MP0001853_heart_inflammation1.92725956
40MP0004947_skin_inflammation1.92153559
41MP0002006_tumorigenesis1.91836423
42MP0010234_abnormal_vibrissa_follicle1.88105393
43MP0004808_abnormal_hematopoietic_stem1.85015788
44* MP0002429_abnormal_blood_cell1.84647505
45MP0001845_abnormal_inflammatory_respons1.83992273
46MP0000465_gastrointestinal_hemorrhage1.82224934
47MP0001533_abnormal_skeleton_physiology1.67077042
48MP0000703_abnormal_thymus_morphology1.63980389
49MP0003866_abnormal_defecation1.56756826
50MP0004510_myositis1.55696494
51MP0008877_abnormal_DNA_methylation1.54800517
52MP0002933_joint_inflammation1.54520219
53MP0005451_abnormal_body_composition1.45604894
54MP0005310_abnormal_salivary_gland1.44402456
55MP0003172_abnormal_lysosome_physiology1.38075291
56MP0008469_abnormal_protein_level1.34851791
57MP0005058_abnormal_lysosome_morphology1.33862428
58MP0003111_abnormal_nucleus_morphology1.32115420
59MP0000858_altered_metastatic_potential1.27983548
60MP0000490_abnormal_crypts_of1.26262100
61MP0009764_decreased_sensitivity_to1.22534023
62MP0003448_altered_tumor_morphology1.21814122
63MP0001851_eye_inflammation1.17422892
64MP0005395_other_phenotype1.17237552
65MP0003656_abnormal_erythrocyte_physiolo1.16516563
66MP0005174_abnormal_tail_pigmentation1.13363161
67MP0004957_abnormal_blastocyst_morpholog1.09619774
68MP0008004_abnormal_stomach_pH1.09217221
69MP0003890_abnormal_embryonic-extraembry1.05809624
70MP0009840_abnormal_foam_cell1.05256383
71MP0010352_gastrointestinal_tract_polyps1.04936681
72MP0005075_abnormal_melanosome_morpholog1.04879986
73MP0010307_abnormal_tumor_latency1.03977495
74MP0000350_abnormal_cell_proliferation1.03864748
75MP0002019_abnormal_tumor_incidence1.02919925
76MP0005166_decreased_susceptibility_to1.02710824
77MP0003191_abnormal_cellular_cholesterol1.02111788
78MP0003075_altered_response_to1.02021230
79MP0005647_abnormal_sex_gland1.00757205
80MP0000343_altered_response_to0.97882445
81MP0005023_abnormal_wound_healing0.97042359
82MP0001730_embryonic_growth_arrest0.96437582
83MP0003183_abnormal_peptide_metabolism0.96356473
84MP0003699_abnormal_female_reproductive0.95655953
85MP0001663_abnormal_digestive_system0.93308784
86MP0006054_spinal_hemorrhage0.91910617
87MP0008058_abnormal_DNA_repair0.91552121
88MP0002796_impaired_skin_barrier0.90875452
89MP0003453_abnormal_keratinocyte_physiol0.90440090
90MP0008057_abnormal_DNA_replication0.88396316
91MP0002998_abnormal_bone_remodeling0.87720322
92MP0002132_abnormal_respiratory_system0.86551824
93MP0003566_abnormal_cell_adhesion0.86357571
94MP0003950_abnormal_plasma_membrane0.83575521
95MP0003828_pulmonary_edema0.83570660
96MP0005410_abnormal_fertilization0.81853581
97MP0005076_abnormal_cell_differentiation0.79521481
98MP0000249_abnormal_blood_vessel0.79336916
99MP0009763_increased_sensitivity_to0.76274609
100MP0000604_amyloidosis0.75893885
101MP0008260_abnormal_autophagy0.73855941
102MP0010678_abnormal_skin_adnexa0.73797453
103MP0004264_abnormal_extraembryonic_tissu0.72968712
104MP0001881_abnormal_mammary_gland0.72723961
105MP0003693_abnormal_embryo_hatching0.71679892
106MP0008873_increased_physiological_sensi0.70439535
107MP0002136_abnormal_kidney_physiology0.69961517
108MP0008007_abnormal_cellular_replicative0.69342664
109MP0003252_abnormal_bile_duct0.69246939
110MP0000015_abnormal_ear_pigmentation0.66250729
111MP0002877_abnormal_melanocyte_morpholog0.65840608
112MP0005390_skeleton_phenotype0.64880522
113MP0002254_reproductive_system_inflammat0.63992057
114MP0010094_abnormal_chromosome_stability0.62463552
115MP0009765_abnormal_xenobiotic_induced0.60861137
116MP0003091_abnormal_cell_migration0.60447101
117MP0005164_abnormal_response_to0.59833549
118MP0003077_abnormal_cell_cycle0.59687913
119MP0000313_abnormal_cell_death0.59238296
120MP0003795_abnormal_bone_structure0.57750034
121MP0001915_intracranial_hemorrhage0.57507767
122MP0009931_abnormal_skin_appearance0.54664427
123MP0001879_abnormal_lymphatic_vessel0.53953317
124MP0005621_abnormal_cell_physiology0.52828145
125MP0002095_abnormal_skin_pigmentation0.51918321

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)5.69720007
2Recurrent abscess formation (HP:0002722)5.34803475
3Recurrent bacterial skin infections (HP:0005406)4.97722378
4Cellulitis (HP:0100658)4.64930711
5Recurrent viral infections (HP:0004429)4.57469018
6Recurrent fungal infections (HP:0002841)4.48623086
7Chronic otitis media (HP:0000389)4.27719581
8Stomatitis (HP:0010280)4.23060376
9Mediastinal lymphadenopathy (HP:0100721)4.08270442
10Elevated erythrocyte sedimentation rate (HP:0003565)3.96276249
11B lymphocytopenia (HP:0010976)3.91200215
12Abnormality of B cell number (HP:0010975)3.91200215
13Meningitis (HP:0001287)3.80532803
14Agammaglobulinemia (HP:0004432)3.79712578
15Myositis (HP:0100614)3.73885291
16Abnormality of macrophages (HP:0004311)3.63663414
17Panhypogammaglobulinemia (HP:0003139)3.61319009
18Recurrent gram-negative bacterial infections (HP:0005420)3.56713946
19Recurrent bronchitis (HP:0002837)3.55548394
20Obstructive lung disease (HP:0006536)3.55241265
21Chronic obstructive pulmonary disease (HP:0006510)3.55241265
22Thyroiditis (HP:0100646)3.54818379
23IgM deficiency (HP:0002850)3.53463476
24T lymphocytopenia (HP:0005403)3.51190353
25Recurrent skin infections (HP:0001581)3.49927853
26Abnormality of T cell number (HP:0011839)3.39897617
27Abnormality of liposaccharide metabolism (HP:0010968)3.35966612
28Abnormality of glycosphingolipid metabolism (HP:0004343)3.35966612
29Abnormality of glycolipid metabolism (HP:0010969)3.35966612
30Thrombocytosis (HP:0001894)3.33516334
31Autoimmune hemolytic anemia (HP:0001890)3.30430137
32Inflammation of the large intestine (HP:0002037)3.24206142
33Severe combined immunodeficiency (HP:0004430)3.23403356
34Vasculitis (HP:0002633)3.23018593
35Osteomyelitis (HP:0002754)3.18976762
36Gastrointestinal inflammation (HP:0004386)3.17180796
37Pustule (HP:0200039)3.14663563
38Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.10615153
39Prolonged bleeding time (HP:0003010)3.10121334
40Papilloma (HP:0012740)3.05836305
41Verrucae (HP:0200043)3.05836305
42Combined immunodeficiency (HP:0005387)3.04707411
43Loss of speech (HP:0002371)3.04308650
44Petechiae (HP:0000967)2.98168128
45Abnormality of T cells (HP:0002843)2.88310546
46Chronic mucocutaneous candidiasis (HP:0002728)2.85458706
47Recurrent cutaneous fungal infections (HP:0011370)2.85458706
48Leukocytosis (HP:0001974)2.80973927
49Colitis (HP:0002583)2.80432110
50Gingivitis (HP:0000230)2.76971724
51Prostate neoplasm (HP:0100787)2.75284029
52Abnormal delayed hypersensitivity skin test (HP:0002963)2.75165701
53Epistaxis (HP:0000421)2.73969105
54Sepsis (HP:0100806)2.73362225
55Increased IgM level (HP:0003496)2.71229801
56Eosinophilia (HP:0001880)2.70498545
57Orchitis (HP:0100796)2.68777293
58Optic neuritis (HP:0100653)2.67876565
59Retrobulbar optic neuritis (HP:0100654)2.67876565
60Autoimmune thrombocytopenia (HP:0001973)2.63450582
61Premature loss of primary teeth (HP:0006323)2.63427661
62Nasal polyposis (HP:0100582)2.63378756
63Interstitial pulmonary disease (HP:0006530)2.60229264
64Spontaneous hematomas (HP:0007420)2.58911671
65Gastrointestinal stroma tumor (HP:0100723)2.58581636
66Recurrent pneumonia (HP:0006532)2.54254141
67Cholecystitis (HP:0001082)2.53884454
68Abnormal gallbladder physiology (HP:0012438)2.53884454
69Lymphopenia (HP:0001888)2.52190950
70Abnormality of eosinophils (HP:0001879)2.51208191
71IgG deficiency (HP:0004315)2.49537419
72Hypoplasia of the thymus (HP:0000778)2.48995019
73Granulocytopenia (HP:0001913)2.44800367
74Pulmonary infiltrates (HP:0002113)2.44686243
75Abnormality of cells of the lymphoid lineage (HP:0012140)2.44684937
76Abnormality of T cell physiology (HP:0011840)2.42671060
77Gingival bleeding (HP:0000225)2.41639863
78Abnormality of the vasculature of the conjunctiva (HP:0008054)2.40693866
79Abnormality of the nasal mucosa (HP:0000433)2.40371998
80Abnormality of cells of the erythroid lineage (HP:0012130)2.38928534
81Arterial thrombosis (HP:0004420)2.36607148
82Diminished motivation (HP:0000745)2.35841875
83Periodontitis (HP:0000704)2.35280739
84Vacuolated lymphocytes (HP:0001922)2.34944407
85Anhidrosis (HP:0000970)2.34905050
86Lymphoma (HP:0002665)2.33772882
87Apathy (HP:0000741)2.31949094
88Chronic sinusitis (HP:0011109)2.31826520
89Skin ulcer (HP:0200042)2.28656738
90Chest pain (HP:0100749)2.27265058
91Abnormal number of erythroid precursors (HP:0012131)2.26372901
92Increased IgE level (HP:0003212)2.25717256
93Supernumerary spleens (HP:0009799)2.25316107
94Hemoptysis (HP:0002105)2.24644293
95Acute lymphatic leukemia (HP:0006721)2.22346377
96Abnormality of the prostate (HP:0008775)2.21173401
97Viral hepatitis (HP:0006562)2.18303319
98Emphysema (HP:0002097)2.17969745
99Multiple enchondromatosis (HP:0005701)2.17397618
100Hematochezia (HP:0002573)2.15671701
101Recurrent lower respiratory tract infections (HP:0002783)2.14986660
102Pulmonary fibrosis (HP:0002206)2.12717562
103Intrahepatic cholestasis (HP:0001406)2.10538766
104Fatigue (HP:0012378)2.08297950
105Xerostomia (HP:0000217)2.07048986
106Facial hemangioma (HP:0000329)2.06451057
107Abnormal platelet function (HP:0011869)2.06381259
108Impaired platelet aggregation (HP:0003540)2.06381259
109Hypergammaglobulinemia (HP:0010702)2.05110501
110Abnormality of the fingertips (HP:0001211)2.05008768
111Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.03258001
112Urticaria (HP:0001025)2.03144026
113IgA deficiency (HP:0002720)2.02592892
114Premature ovarian failure (HP:0008209)2.02377832
115Chromsome breakage (HP:0040012)2.02278344
116Gastrointestinal infarctions (HP:0005244)2.00883864
117Chromosomal breakage induced by crosslinking agents (HP:0003221)2.00024194
118Conjunctival telangiectasia (HP:0000524)1.98618778
119Recurrent sinusitis (HP:0011108)1.98209436
120Hepatosplenomegaly (HP:0001433)1.98018587
121Encephalitis (HP:0002383)1.95937549
122Restrictive lung disease (HP:0002091)1.95362797
123Papillary thyroid carcinoma (HP:0002895)1.94981020
124Keratoconjunctivitis sicca (HP:0001097)1.94850831
125Increased serum ferritin (HP:0003281)1.94638313
126Increased cerebral lipofuscin (HP:0011813)1.93757562
127Skin rash (HP:0000988)1.93194654
128Amaurosis fugax (HP:0100576)1.92236489
129Metaphyseal irregularity (HP:0003025)1.92222935
130Chronic diarrhea (HP:0002028)1.91781732
131Disinhibition (HP:0000734)1.91349577
132Lower limb hyperreflexia (HP:0002395)1.89421307
133Malnutrition (HP:0004395)1.88325732
134Neutropenia (HP:0001875)1.88116657
135Agnosia (HP:0010524)1.85615604
136Aplastic anemia (HP:0001915)1.83936095

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.55838248
2RIPK43.28235022
3PRPF4B3.21710889
4MAP3K102.90499284
5EIF2AK32.82384169
6ARAF2.77782086
7EEF2K2.71678419
8MAP3K142.66255991
9TBK12.51019485
10JAK32.50669237
11TXK2.49928055
12TYK22.28154759
13MAP3K92.25760369
14IKBKE2.21504419
15BTK2.09583146
16GRK62.08868739
17ZAP702.07518642
18BLK2.03097570
19STK102.03040622
20KIT2.00830654
21TEC2.00069596
22NEK91.90406415
23ERN11.82018360
24ITK1.79802667
25SYK1.79612625
26IKBKB1.75840906
27PIM21.70612922
28MAP3K131.64808995
29MOS1.61440273
30PIM11.60220942
31FES1.59342411
32IRAK41.55040893
33MST41.54553287
34TAOK21.48535093
35JAK11.45059390
36HCK1.44966244
37LRRK21.42435578
38PBK1.39529334
39LCK1.37073133
40KDR1.35899356
41NME21.34130234
42EPHB11.32488304
43CSK1.31953834
44RPS6KB21.31565508
45MAP2K31.24975642
46CSF1R1.23090259
47RPS6KA41.22397683
48NEK61.21388024
49TGFBR21.18716408
50LYN1.18272294
51TTK1.18221692
52SIK21.17286998
53CDC71.16667640
54MAP3K111.15739867
55BRAF1.14296488
56PKN21.08894314
57MATK1.04306844
58STK41.03251266
59CLK11.02725401
60BRD41.02645969
61TAOK31.01240549
62FLT30.97274557
63SCYL20.96731173
64TESK20.96547421
65CHUK0.93222180
66TRIB30.92555507
67JAK20.92213340
68NLK0.91485958
69EIF2AK20.84393688
70SMG10.82670622
71AURKA0.81970685
72FGFR40.81643610
73RAF10.80625869
74CDK40.78532222
75GRK70.77653166
76TRPM70.76525655
77KSR20.75656298
78MARK30.75424394
79IRAK30.73234551
80MAP3K70.73083638
81CDK70.66710665
82PRKCI0.66006133
83TIE10.65968759
84RIPK10.65350803
85MAP3K30.65271190
86MAP3K120.62341024
87MAPK40.61797103
88MAPKAPK30.61361685
89FGFR30.61290066
90HIPK20.58590303
91ZAK0.57048348
92NEK20.56982745
93STK240.56160393
94CDK120.56005695
95FGR0.55625665
96ACVR1B0.52910685
97SIK30.50410686
98VRK10.49940330
99ABL10.48526841
100PRKCQ0.48083392
101TAOK10.47401791
102MAP3K10.47383895
103MAP3K80.46731961
104CDK60.45888737
105MAPKAPK20.45671658
106MAPKAPK50.44277370
107IRAK10.43542206
108PTK60.42872595
109PRKG20.41837978
110EGFR0.39042529
111CHEK10.38504921
112MARK20.37616306
113MAP3K50.36816168
114PIK3CG0.36796036
115STK30.36551400
116RPS6KA50.36033056
117TNK20.35596479
118RPS6KA60.34115056
119PDK10.33680151
120PLK10.33582699
121BMPR20.33432795
122MAPK110.32926458
123PRKCD0.32195477
124MKNK10.31476709
125PLK40.31398989
126MAPK30.29157809
127MELK0.28043709
128FYN0.25044283
129CDK90.23256219
130TGFBR10.21390873

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.49263894
2Leishmaniasis_Homo sapiens_hsa051403.04289527
3B cell receptor signaling pathway_Homo sapiens_hsa046622.83251771
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.67501390
5Osteoclast differentiation_Homo sapiens_hsa043802.49732793
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.32467383
7Measles_Homo sapiens_hsa051622.20991014
8Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.11873428
9Hematopoietic cell lineage_Homo sapiens_hsa046402.11076866
10Intestinal immune network for IgA production_Homo sapiens_hsa046722.10635860
11Allograft rejection_Homo sapiens_hsa053302.10569206
12Toll-like receptor signaling pathway_Homo sapiens_hsa046202.06662970
13Graft-versus-host disease_Homo sapiens_hsa053321.97132696
14RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.96767140
15T cell receptor signaling pathway_Homo sapiens_hsa046601.92413153
16Antigen processing and presentation_Homo sapiens_hsa046121.84247769
17NOD-like receptor signaling pathway_Homo sapiens_hsa046211.69468156
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.68946140
19Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.67433577
20Jak-STAT signaling pathway_Homo sapiens_hsa046301.63961751
21Legionellosis_Homo sapiens_hsa051341.63534428
22Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.63120741
23Asthma_Homo sapiens_hsa053101.62908841
24Herpes simplex infection_Homo sapiens_hsa051681.58776360
25Tuberculosis_Homo sapiens_hsa051521.57963959
26Malaria_Homo sapiens_hsa051441.56933478
27Toxoplasmosis_Homo sapiens_hsa051451.56832746
28Cell cycle_Homo sapiens_hsa041101.54360935
29Influenza A_Homo sapiens_hsa051641.51356428
30Staphylococcus aureus infection_Homo sapiens_hsa051501.50136431
31TNF signaling pathway_Homo sapiens_hsa046681.49244791
32Acute myeloid leukemia_Homo sapiens_hsa052211.48122714
33Chemokine signaling pathway_Homo sapiens_hsa040621.44522234
34Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.44251246
35Hepatitis B_Homo sapiens_hsa051611.42820064
36Apoptosis_Homo sapiens_hsa042101.41465150
37Pertussis_Homo sapiens_hsa051331.40684594
38Chronic myeloid leukemia_Homo sapiens_hsa052201.36223911
39Shigellosis_Homo sapiens_hsa051311.32744914
40Leukocyte transendothelial migration_Homo sapiens_hsa046701.26556271
41Ribosome_Homo sapiens_hsa030101.25253199
42AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.16449106
43Salmonella infection_Homo sapiens_hsa051321.15059855
44Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.13296767
45Transcriptional misregulation in cancer_Homo sapiens_hsa052021.12200176
46Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.10948037
47Platelet activation_Homo sapiens_hsa046111.09231237
48Basal transcription factors_Homo sapiens_hsa030221.04992509
49Pancreatic cancer_Homo sapiens_hsa052121.04265494
50Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.02275076
51African trypanosomiasis_Homo sapiens_hsa051431.00125950
52Non-homologous end-joining_Homo sapiens_hsa034500.96609512
53Hepatitis C_Homo sapiens_hsa051600.96257919
54Rheumatoid arthritis_Homo sapiens_hsa053230.95788288
55Glycosaminoglycan degradation_Homo sapiens_hsa005310.93911371
56Other glycan degradation_Homo sapiens_hsa005110.92465688
57Viral carcinogenesis_Homo sapiens_hsa052030.91903591
58RNA degradation_Homo sapiens_hsa030180.90566305
59Epstein-Barr virus infection_Homo sapiens_hsa051690.88391103
60Small cell lung cancer_Homo sapiens_hsa052220.86797086
61Autoimmune thyroid disease_Homo sapiens_hsa053200.80447891
62VEGF signaling pathway_Homo sapiens_hsa043700.80344906
63Neurotrophin signaling pathway_Homo sapiens_hsa047220.79803044
64Lysosome_Homo sapiens_hsa041420.79143884
65RNA transport_Homo sapiens_hsa030130.79078650
66Type I diabetes mellitus_Homo sapiens_hsa049400.78760228
67Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.75512231
68HTLV-I infection_Homo sapiens_hsa051660.75106211
69Systemic lupus erythematosus_Homo sapiens_hsa053220.74137531
70DNA replication_Homo sapiens_hsa030300.74003225
71Prolactin signaling pathway_Homo sapiens_hsa049170.73857381
72Non-small cell lung cancer_Homo sapiens_hsa052230.72843872
73Sulfur relay system_Homo sapiens_hsa041220.71549423
74Viral myocarditis_Homo sapiens_hsa054160.69610797
75Spliceosome_Homo sapiens_hsa030400.65651760
76Base excision repair_Homo sapiens_hsa034100.65552229
77Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63879987
78Nucleotide excision repair_Homo sapiens_hsa034200.63416170
79Dorso-ventral axis formation_Homo sapiens_hsa043200.62897443
80HIF-1 signaling pathway_Homo sapiens_hsa040660.61569316
81Amoebiasis_Homo sapiens_hsa051460.61389479
82Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.60176961
83Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.57403032
84Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.56258743
85Cysteine and methionine metabolism_Homo sapiens_hsa002700.55166677
86Phagosome_Homo sapiens_hsa041450.53175812
87Homologous recombination_Homo sapiens_hsa034400.53040218
88Oocyte meiosis_Homo sapiens_hsa041140.51937153
89mRNA surveillance pathway_Homo sapiens_hsa030150.51373707
90Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50982686
91Bladder cancer_Homo sapiens_hsa052190.50303357
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.49796798
93Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.46055861
94Colorectal cancer_Homo sapiens_hsa052100.45150355
95Caffeine metabolism_Homo sapiens_hsa002320.43964020
96Pentose phosphate pathway_Homo sapiens_hsa000300.43737570
97p53 signaling pathway_Homo sapiens_hsa041150.43343170
98Renal cell carcinoma_Homo sapiens_hsa052110.43315266
99Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43127936
100Carbohydrate digestion and absorption_Homo sapiens_hsa049730.41220226
101Fanconi anemia pathway_Homo sapiens_hsa034600.39373873
102MicroRNAs in cancer_Homo sapiens_hsa052060.36778373
103FoxO signaling pathway_Homo sapiens_hsa040680.35395348
104Sphingolipid metabolism_Homo sapiens_hsa006000.33815680
105Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.33158534
106Notch signaling pathway_Homo sapiens_hsa043300.30363644
107Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.29920609
108Adipocytokine signaling pathway_Homo sapiens_hsa049200.29522640
109MAPK signaling pathway_Homo sapiens_hsa040100.29012511
110Endocytosis_Homo sapiens_hsa041440.28015119
111Thyroid cancer_Homo sapiens_hsa052160.27874241
112Prostate cancer_Homo sapiens_hsa052150.27273833
113Inositol phosphate metabolism_Homo sapiens_hsa005620.25012095
114ABC transporters_Homo sapiens_hsa020100.24761137
115Regulation of actin cytoskeleton_Homo sapiens_hsa048100.24685094
116Renin-angiotensin system_Homo sapiens_hsa046140.23072754
117Phosphatidylinositol signaling system_Homo sapiens_hsa040700.22795252
118Mismatch repair_Homo sapiens_hsa034300.22327314
119mTOR signaling pathway_Homo sapiens_hsa041500.22040884

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