B3GNT8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1doxorubicin metabolic process (GO:0044598)8.03057101
2daunorubicin metabolic process (GO:0044597)8.03057101
3polyketide metabolic process (GO:0030638)8.03057101
4viral transcription (GO:0019083)5.79104848
5negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.69099155
6translational termination (GO:0006415)5.35540541
7detection of other organism (GO:0098543)5.35368290
8detection of bacterium (GO:0016045)5.28671473
9DNA deamination (GO:0045006)5.27100647
10ribosomal small subunit assembly (GO:0000028)5.24104029
11aminoglycoside antibiotic metabolic process (GO:0030647)4.92857502
12ribosomal small subunit biogenesis (GO:0042274)4.71238849
13SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.67616068
14cotranslational protein targeting to membrane (GO:0006613)4.60619559
15protein targeting to ER (GO:0045047)4.57765587
16response to peptidoglycan (GO:0032494)4.45401784
17translational elongation (GO:0006414)4.39804528
18establishment of protein localization to endoplasmic reticulum (GO:0072599)4.35947494
19detection of external biotic stimulus (GO:0098581)4.30728302
20regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.27979575
21protein localization to endoplasmic reticulum (GO:0070972)4.27450525
22macrophage activation involved in immune response (GO:0002281)4.23464728
23negative regulation of phagocytosis (GO:0050765)4.21693786
24leukocyte migration involved in inflammatory response (GO:0002523)4.13163341
25maturation of SSU-rRNA (GO:0030490)4.05257582
26neutrophil activation involved in immune response (GO:0002283)4.04325017
27cellular protein complex disassembly (GO:0043624)4.04188854
28viral life cycle (GO:0019058)3.97817015
29B cell receptor signaling pathway (GO:0050853)3.96696890
30positive regulation of B cell differentiation (GO:0045579)3.84635387
31positive regulation of gamma-delta T cell activation (GO:0046645)3.79611760
32respiratory burst (GO:0045730)3.78663941
33lymphoid progenitor cell differentiation (GO:0002320)3.73564025
34response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.73378814
35response to host immune response (GO:0052572)3.73378814
36negative regulation of lymphocyte mediated immunity (GO:0002707)3.71669716
37cellular response to zinc ion (GO:0071294)3.70499707
38detection of biotic stimulus (GO:0009595)3.68164615
39nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.65720516
40neutrophil mediated immunity (GO:0002446)3.65290579
41regulation of myeloid leukocyte mediated immunity (GO:0002886)3.61058617
42regulation of B cell receptor signaling pathway (GO:0050855)3.59760422
43pinocytosis (GO:0006907)3.59500142
44negative regulation of leukocyte mediated immunity (GO:0002704)3.53690813
45regulation of leukocyte degranulation (GO:0043300)3.50187137
46protein complex disassembly (GO:0043241)3.49605246
47ribosomal large subunit biogenesis (GO:0042273)3.45549806
48positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.41892144
49response to interleukin-15 (GO:0070672)3.41734495
50response to host (GO:0075136)3.41117931
51response to host defenses (GO:0052200)3.41117931
52response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.41117931
53regulation of gamma-delta T cell activation (GO:0046643)3.31079920
54type I interferon signaling pathway (GO:0060337)3.30905739
55cellular response to type I interferon (GO:0071357)3.30905739
56microglial cell activation (GO:0001774)3.30867796
57myeloid cell activation involved in immune response (GO:0002275)3.30003605
58macromolecular complex disassembly (GO:0032984)3.29129454
59translational initiation (GO:0006413)3.27786165
60response to type I interferon (GO:0034340)3.27309362
61positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.25824443
62negative regulation of mast cell activation (GO:0033004)3.25654381
63regulation of mast cell degranulation (GO:0043304)3.24548202
64macrophage activation (GO:0042116)3.23329588
65regulation of interferon-beta biosynthetic process (GO:0045357)3.23209017
66regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.22632372
67regulation of mast cell activation (GO:0033003)3.21320688
68regulation of dendritic cell antigen processing and presentation (GO:0002604)3.20113991
69negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.20076221
70B cell mediated immunity (GO:0019724)3.15655667
71Arp2/3 complex-mediated actin nucleation (GO:0034314)3.13914961
72antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.12587937
73antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.12587937
74cellular response to interleukin-15 (GO:0071350)3.12134914
75neutrophil activation (GO:0042119)3.10691728
76regulation of B cell differentiation (GO:0045577)3.09796595
77antigen processing and presentation of endogenous antigen (GO:0019883)3.09457662
78production of molecular mediator involved in inflammatory response (GO:0002532)3.08779922
79negative regulation of interleukin-6 production (GO:0032715)3.06881321
80regulation of antigen processing and presentation (GO:0002577)3.06465569
81regulation of mast cell activation involved in immune response (GO:0033006)3.05270267
82regulation of regulated secretory pathway (GO:1903305)3.02791425
83interferon-gamma-mediated signaling pathway (GO:0060333)3.01094777
84leukocyte degranulation (GO:0043299)3.00365514
85antigen processing and presentation via MHC class Ib (GO:0002475)3.00107200
86T cell homeostasis (GO:0043029)2.97916331
87germinal center formation (GO:0002467)2.97230354
88negative regulation of innate immune response (GO:0045824)2.97000189
89detection of molecule of bacterial origin (GO:0032490)2.96064406
90negative regulation of granulocyte differentiation (GO:0030853)2.95342235
91regulation of gamma-delta T cell differentiation (GO:0045586)2.93296247
92regulation of T cell mediated cytotoxicity (GO:0001914)2.92940241
93negative regulation of cytokine production involved in immune response (GO:0002719)2.92020950
94protein targeting to membrane (GO:0006612)2.89544280
95response to muramyl dipeptide (GO:0032495)2.88126791
96positive regulation of T cell mediated cytotoxicity (GO:0001916)2.86610463
97antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.86144212
98cellular extravasation (GO:0045123)2.85745485
99immunoglobulin mediated immune response (GO:0016064)2.85578625
100regulation of cellular extravasation (GO:0002691)2.85470396
101regulation of T cell tolerance induction (GO:0002664)2.85151265
102negative regulation of T cell mediated immunity (GO:0002710)2.84970812
103defense response to fungus (GO:0050832)2.83300754
104mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.82756546
105mitochondrial respiratory chain complex I assembly (GO:0032981)2.82756546
106NADH dehydrogenase complex assembly (GO:0010257)2.82756546
107NIK/NF-kappaB signaling (GO:0038061)2.81904522
108regulation of interleukin-6 biosynthetic process (GO:0045408)2.80985217
109positive regulation of mast cell activation (GO:0033005)2.80256653
110lipopolysaccharide-mediated signaling pathway (GO:0031663)2.79721113
111response to fungus (GO:0009620)2.77816448
112killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.77236970
113disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.77236970
114defense response to protozoan (GO:0042832)2.77109195
115positive regulation of antigen processing and presentation (GO:0002579)2.76732679
116glycoside metabolic process (GO:0016137)2.76452416
117modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.74481081
118positive regulation by organism of defense response of other organism involved in symbiotic interact2.74481081
119modulation by symbiont of host immune response (GO:0052553)2.74481081
120positive regulation by symbiont of host defense response (GO:0052509)2.74481081
121modulation by symbiont of host defense response (GO:0052031)2.74481081
122modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.74481081
123diol metabolic process (GO:0034311)2.74475499
124dendritic cell chemotaxis (GO:0002407)2.73897051
125regulation of tolerance induction (GO:0002643)2.73850284
126leukocyte aggregation (GO:0070486)2.72817533
127sphingoid metabolic process (GO:0046519)2.69633053
128mast cell activation (GO:0045576)2.68953882
129positive regulation of mast cell degranulation (GO:0043306)2.68596667
130positive regulation of mast cell activation involved in immune response (GO:0033008)2.68596667
131granulocyte activation (GO:0036230)2.68411326
132positive regulation of Cdc42 GTPase activity (GO:0043089)2.67683100
133regulation of T-helper 2 cell differentiation (GO:0045628)2.66044908
134superoxide anion generation (GO:0042554)2.65512708
135mitochondrial calcium ion transport (GO:0006851)2.64141392
136dendritic cell migration (GO:0036336)2.63391080
137positive thymic T cell selection (GO:0045059)2.62859557
138tRNA methylation (GO:0030488)2.61585170
139positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.61551652
140myeloid leukocyte activation (GO:0002274)2.60536658
141neutrophil chemotaxis (GO:0030593)2.60385935
142actin nucleation (GO:0045010)2.59328776
143negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.57700115
144mature B cell differentiation (GO:0002335)2.57473008
145regulation of platelet aggregation (GO:0090330)2.55806923
146lymphocyte homeostasis (GO:0002260)2.55123921
147leukotriene metabolic process (GO:0006691)2.53620907
148myeloid leukocyte mediated immunity (GO:0002444)2.52209668
149negative regulation of calcium ion transport into cytosol (GO:0010523)2.52159114
150protein complex biogenesis (GO:0070271)2.51577791
151B cell homeostasis (GO:0001782)2.50806746
152negative regulation of erythrocyte differentiation (GO:0045647)2.50484563
153C-terminal protein lipidation (GO:0006501)2.50231613
154B cell activation (GO:0042113)2.49628997
155negative regulation of interleukin-12 production (GO:0032695)2.49268299
156telomere maintenance via semi-conservative replication (GO:0032201)2.49035543
157negative regulation of cell killing (GO:0031342)2.48971514

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.23506559
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.07409078
3CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human4.05330842
4MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.59509858
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.37270528
6* VDR_21846776_ChIP-Seq_THP-1_Human3.25901279
7SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.24807696
8SCL_19346495_ChIP-Seq_HPC-7_Human3.21983947
9IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.08698926
10SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.95507572
11FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.93659055
12RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.92219393
13IRF8_21731497_ChIP-ChIP_J774_Mouse2.86844711
14LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.77740137
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.70924962
16SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.57063313
17E2F7_22180533_ChIP-Seq_HELA_Human2.48408219
18IRF8_27001747_Chip-Seq_BMDM_Mouse2.44913018
19VDR_24763502_ChIP-Seq_THP-1_Human2.41158057
20SPI1_23547873_ChIP-Seq_NB4_Human2.40558126
21MEIS1_20887958_ChIP-Seq_HPC-7_Mouse2.26872267
22MYB_21317192_ChIP-Seq_ERMYB_Mouse2.26700544
23KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.07431188
24TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.06936458
25NOTCH1_21737748_ChIP-Seq_TLL_Human1.99189757
26GABP_17652178_ChIP-ChIP_JURKAT_Human1.96912823
27STAT4_19710469_ChIP-ChIP_TH1__Mouse1.96100701
28ERG_20887958_ChIP-Seq_HPC-7_Mouse1.95837877
29CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.95018091
30TCF7_22412390_ChIP-Seq_EML_Mouse1.93906007
31LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.93031398
32NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.91133196
33SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.90925609
34KDM2B_26808549_Chip-Seq_SUP-B15_Human1.89927288
35NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.86797561
36RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.82027790
37JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.82000484
38STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.78903389
39ELK3_25401928_ChIP-Seq_HUVEC_Human1.77683373
40THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.77048655
41HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.75542420
42BRD4_27068464_Chip-Seq_AML-cells_Mouse1.73645237
43STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.71708527
44FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.71170781
45RUNX1_22412390_ChIP-Seq_EML_Mouse1.69696732
46HOXB4_20404135_ChIP-ChIP_EML_Mouse1.68974799
47KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.66819412
48KDM2B_26808549_Chip-Seq_DND41_Human1.65911085
49GATA1_19941826_ChIP-Seq_K562_Human1.65409105
50STAT1_20625510_ChIP-Seq_HELA_Human1.65184501
51MYC_22102868_ChIP-Seq_BL_Human1.64820387
52GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.64427173
53IKZF1_21737484_ChIP-ChIP_HCT116_Human1.59353332
54NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.57081268
55E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.57066438
56HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.55644768
57MAF_26560356_Chip-Seq_TH1_Human1.53584846
58EST1_17652178_ChIP-ChIP_JURKAT_Human1.52971741
59Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.52429410
60SRF_21415370_ChIP-Seq_HL-1_Mouse1.50293996
61TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.49376490
62CIITA_25753668_ChIP-Seq_RAJI_Human1.47660927
63FOXP3_21729870_ChIP-Seq_TREG_Human1.47300601
64BCOR_27268052_Chip-Seq_Bcells_Human1.46508565
65GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.46415244
66VDR_23849224_ChIP-Seq_CD4+_Human1.45550889
67IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.44490660
68UTX_26944678_Chip-Seq_JUKART_Human1.44214336
69STAT6_21828071_ChIP-Seq_BEAS2B_Human1.39991897
70MAF_26560356_Chip-Seq_TH2_Human1.39799111
71ETS1_20019798_ChIP-Seq_JURKAT_Human1.39419518
72GATA2_22383799_ChIP-Seq_G1ME_Mouse1.37920436
73GATA1_22383799_ChIP-Seq_G1ME_Mouse1.37767102
74VDR_24787735_ChIP-Seq_THP-1_Human1.37221541
75FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.31044274
76FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.30486105
77CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.30443268
78* GATA3_27048872_Chip-Seq_THYMUS_Human1.30254307
79MYB_26560356_Chip-Seq_TH2_Human1.28463030
80RACK7_27058665_Chip-Seq_MCF-7_Human1.22998035
81KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.20967536
82TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20738987
83SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20098181
84RARG_19884340_ChIP-ChIP_MEFs_Mouse1.19651006
85PU_27001747_Chip-Seq_BMDM_Mouse1.19118559
86EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.18534952
87EGR1_19374776_ChIP-ChIP_THP-1_Human1.17645682
88FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.17335529
89SA1_27219007_Chip-Seq_ERYTHROID_Human1.17261981
90SPI1_23127762_ChIP-Seq_K562_Human1.16052621
91PPARA_22158963_ChIP-Seq_LIVER_Mouse1.15742049
92* GATA2_19941826_ChIP-Seq_K562_Human1.15067064
93GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.15022940
94ELF1_20517297_ChIP-Seq_JURKAT_Human1.13797085
95BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.13487096
96GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13347854
97STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.13206890
98GATA1_19941827_ChIP-Seq_MEL_Mouse1.12420636
99NCOR1_26117541_ChIP-Seq_K562_Human1.12354359
100MYB_26560356_Chip-Seq_TH1_Human1.12257835
101CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.11980530
102P68_20966046_ChIP-Seq_HELA_Human1.11543102
103* GATA2_21666600_ChIP-Seq_HMVEC_Human1.11386730
104EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.11271980
105TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.11251250
106SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09633814
107VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.08438422
108YY1_21170310_ChIP-Seq_MESCs_Mouse1.08237052
109CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.07958469
110NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.07801595
111RXR_22158963_ChIP-Seq_LIVER_Mouse1.07695198
112MYC_18358816_ChIP-ChIP_MESCs_Mouse1.07588733
113* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07088967
114FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.07047463
115MYC_18940864_ChIP-ChIP_HL60_Human1.06434069
116RUNX_20019798_ChIP-Seq_JUKART_Human1.06347688
117GATA1_22025678_ChIP-Seq_K562_Human1.05932779
118PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05860184
119MYC_18555785_ChIP-Seq_MESCs_Mouse1.03694967
120SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.03168929
121BCL6_27268052_Chip-Seq_Bcells_Human1.02598190
122MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.01866699
123CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01205881
124CTCF_18555785_ChIP-Seq_MESCs_Mouse1.01052765
125PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00763897
126EZH2_22144423_ChIP-Seq_EOC_Human0.97848365
127ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.97465119
128XRN2_22483619_ChIP-Seq_HELA_Human0.97191953
129VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.96640112
130DCP1A_22483619_ChIP-Seq_HELA_Human0.96361667
131RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.96129340
132GATA3_26560356_Chip-Seq_TH2_Human0.95984548
133TTF2_22483619_ChIP-Seq_HELA_Human0.95983733
134SPI1_20517297_ChIP-Seq_HL60_Human0.95221449
135PU.1_20513432_ChIP-Seq_Bcells_Mouse0.95010760
136KDM2B_26808549_Chip-Seq_JURKAT_Human0.94030352
137CTCF_26484167_Chip-Seq_Bcells_Mouse0.93578150
138SA1_27219007_Chip-Seq_Bcells_Human0.92563762
139YY1_22570637_ChIP-Seq_MALME-3M_Human0.92456991
140CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90103675
141PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.88438227
142LXR_22292898_ChIP-Seq_THP-1_Human0.87817712
143CTCF_27219007_Chip-Seq_ERYTHROID_Human0.87811686

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.30021518
2MP0003191_abnormal_cellular_cholesterol3.07982568
3MP0001800_abnormal_humoral_immune2.84139279
4MP0005174_abnormal_tail_pigmentation2.71570436
5MP0001986_abnormal_taste_sensitivity2.71477409
6MP0009785_altered_susceptibility_to2.58121161
7MP0001790_abnormal_immune_system2.57463675
8MP0005387_immune_system_phenotype2.57463675
9MP0000685_abnormal_immune_system2.53540120
10MP0002452_abnormal_antigen_presenting2.50439767
11MP0002419_abnormal_innate_immunity2.45095781
12MP0005000_abnormal_immune_tolerance2.39808941
13MP0002723_abnormal_immune_serum2.36519696
14MP0003436_decreased_susceptibility_to2.36463203
15MP0004381_abnormal_hair_follicle2.33988519
16MP0002396_abnormal_hematopoietic_system2.32969934
17MP0005025_abnormal_response_to2.30725208
18MP0002148_abnormal_hypersensitivity_rea2.23826089
19MP0002420_abnormal_adaptive_immunity2.22921112
20MP0003172_abnormal_lysosome_physiology2.22351853
21MP0001819_abnormal_immune_cell2.20111715
22MP0005671_abnormal_response_to2.18951314
23MP0005409_darkened_coat_color2.18194636
24MP0009379_abnormal_foot_pigmentation2.17294998
25MP0003300_gastrointestinal_ulcer2.08691161
26MP0003303_peritoneal_inflammation2.06723836
27MP0000716_abnormal_immune_system1.93729216
28MP0003646_muscle_fatigue1.92006170
29MP0002398_abnormal_bone_marrow1.89664462
30MP0003724_increased_susceptibility_to1.87959831
31MP0003806_abnormal_nucleotide_metabolis1.87553651
32MP0003011_delayed_dark_adaptation1.82187730
33MP0000465_gastrointestinal_hemorrhage1.82011703
34MP0005464_abnormal_platelet_physiology1.75414619
35MP0000689_abnormal_spleen_morphology1.74677242
36MP0001873_stomach_inflammation1.73022544
37MP0003136_yellow_coat_color1.70055886
38MP0004947_skin_inflammation1.64480754
39MP0002429_abnormal_blood_cell1.61665869
40MP0001188_hyperpigmentation1.61343853
41MP0001984_abnormal_olfaction1.59474639
42MP0003075_altered_response_to1.57830637
43MP0008260_abnormal_autophagy1.55737763
44MP0004510_myositis1.55140063
45MP0002722_abnormal_immune_system1.54197640
46MP0006082_CNS_inflammation1.53106084
47MP0005645_abnormal_hypothalamus_physiol1.52748043
48MP0005058_abnormal_lysosome_morphology1.52319455
49MP0002132_abnormal_respiratory_system1.51330569
50MP0000015_abnormal_ear_pigmentation1.47655744
51MP0003828_pulmonary_edema1.46424689
52MP0003878_abnormal_ear_physiology1.46036949
53MP0005377_hearing/vestibular/ear_phenot1.46036949
54MP0002638_abnormal_pupillary_reflex1.45553788
55MP0009333_abnormal_splenocyte_physiolog1.45138299
56MP0001845_abnormal_inflammatory_respons1.41123682
57MP0009840_abnormal_foam_cell1.39281728
58MP0002095_abnormal_skin_pigmentation1.38891409
59MP0004808_abnormal_hematopoietic_stem1.37389046
60MP0008004_abnormal_stomach_pH1.36940270
61MP0001851_eye_inflammation1.36916844
62MP0005360_urolithiasis1.35910901
63MP0003763_abnormal_thymus_physiology1.35841722
64MP0006292_abnormal_olfactory_placode1.34865588
65MP0002277_abnormal_respiratory_mucosa1.32709445
66MP0002405_respiratory_system_inflammati1.28989634
67MP0005166_decreased_susceptibility_to1.23291756
68MP0005075_abnormal_melanosome_morpholog1.22321244
69MP0002933_joint_inflammation1.21682931
70MP0008469_abnormal_protein_level1.20718176
71MP0010155_abnormal_intestine_physiology1.18484039
72MP0009764_decreased_sensitivity_to1.17320077
73MP0001853_heart_inflammation1.16532688
74MP0000566_synostosis1.16376889
75MP0001663_abnormal_digestive_system1.16160428
76MP0000490_abnormal_crypts_of1.15992495
77MP0003656_abnormal_erythrocyte_physiolo1.11861995
78MP0006276_abnormal_autonomic_nervous1.10890677
79MP0000703_abnormal_thymus_morphology1.10888148
80MP0003866_abnormal_defecation1.09322282
81MP0002166_altered_tumor_susceptibility1.07729655
82MP0009697_abnormal_copulation1.03525643
83MP0005083_abnormal_biliary_tract1.03434048
84MP0009278_abnormal_bone_marrow1.00188005
85MP0002139_abnormal_hepatobiliary_system0.99783846
86MP0002138_abnormal_hepatobiliary_system0.98012857
87MP0001533_abnormal_skeleton_physiology0.97693023
88MP0000343_altered_response_to0.97549963
89MP0002735_abnormal_chemical_nociception0.96933929
90MP0004883_abnormal_blood_vessel0.95630752
91MP0004742_abnormal_vestibular_system0.94706842
92MP0004264_abnormal_extraembryonic_tissu0.94519969
93MP0000372_irregular_coat_pigmentation0.92539046
94MP0000681_abnormal_thyroid_gland0.92489303
95MP0000604_amyloidosis0.91718727
96MP0004142_abnormal_muscle_tone0.90386407
97MP0005164_abnormal_response_to0.89629393
98MP0005390_skeleton_phenotype0.89524529
99MP0008058_abnormal_DNA_repair0.83762598
100MP0003183_abnormal_peptide_metabolism0.82511906
101MP0005310_abnormal_salivary_gland0.82264277
102MP0001485_abnormal_pinna_reflex0.81651427
103MP0005381_digestive/alimentary_phenotyp0.81329510
104MP0005319_abnormal_enzyme/_coenzyme0.81285690
105MP0009763_increased_sensitivity_to0.81229964
106MP0000858_altered_metastatic_potential0.79913252
107MP0003879_abnormal_hair_cell0.79373530
108MP0002998_abnormal_bone_remodeling0.79320903
109MP0005085_abnormal_gallbladder_physiolo0.78264270
110MP0003448_altered_tumor_morphology0.77161186
111MP0004858_abnormal_nervous_system0.76268380
112MP0002751_abnormal_autonomic_nervous0.76155837
113MP0003690_abnormal_glial_cell0.75152144
114MP0005397_hematopoietic_system_phenotyp0.74815308
115MP0001545_abnormal_hematopoietic_system0.74815308
116MP0008995_early_reproductive_senescence0.72776255
117MP0002006_tumorigenesis0.71860448
118MP0003795_abnormal_bone_structure0.70503750
119MP0003693_abnormal_embryo_hatching0.68566048
120MP0009765_abnormal_xenobiotic_induced0.68472839
121MP0002019_abnormal_tumor_incidence0.68202361
122MP0004147_increased_porphyrin_level0.66457283
123MP0000249_abnormal_blood_vessel0.66371784
124MP0000678_abnormal_parathyroid_gland0.66256355
125MP0005451_abnormal_body_composition0.64915847
126MP0005365_abnormal_bile_salt0.63638879
127MP0003786_premature_aging0.61983419
128MP0010234_abnormal_vibrissa_follicle0.61090703
129MP0005257_abnormal_intraocular_pressure0.60465749
130MP0000609_abnormal_liver_physiology0.60307286
131MP0008874_decreased_physiological_sensi0.58515731
132MP0004019_abnormal_vitamin_homeostasis0.57559640
133MP0006054_spinal_hemorrhage0.57105956
134MP0003045_fibrosis0.56143836

Predicted human phenotypes

RankGene SetZ-score
1Orchitis (HP:0100796)4.97424267
2Reticulocytopenia (HP:0001896)4.34617878
3Hypochromic microcytic anemia (HP:0004840)4.21361717
4Agammaglobulinemia (HP:0004432)4.13134373
5Recurrent abscess formation (HP:0002722)4.09225338
6Chronic otitis media (HP:0000389)3.87888814
7Gastrointestinal infarctions (HP:0005244)3.84363786
8Meningitis (HP:0001287)3.74875570
9Increased IgE level (HP:0003212)3.73861805
10Abnormality of cells of the erythroid lineage (HP:0012130)3.66142715
11Gingivitis (HP:0000230)3.61215101
12Parakeratosis (HP:0001036)3.58842067
13Hypochromic anemia (HP:0001931)3.48977676
14Abnormal number of erythroid precursors (HP:0012131)3.46117592
15Recurrent bacterial skin infections (HP:0005406)3.42881107
16Obstructive lung disease (HP:0006536)3.42184574
17Chronic obstructive pulmonary disease (HP:0006510)3.42184574
18Cellulitis (HP:0100658)3.39508033
19Encephalitis (HP:0002383)3.33076715
20Eczematoid dermatitis (HP:0000976)3.27396904
21Hepatocellular necrosis (HP:0001404)3.25355516
22Pustule (HP:0200039)3.22931606
23Abnormality of DNA repair (HP:0003254)3.19238245
24Vacuolated lymphocytes (HP:0001922)3.19035277
25Abnormality of B cell number (HP:0010975)3.18649775
26B lymphocytopenia (HP:0010976)3.18649775
27Episodic fever (HP:0001954)3.18013265
28Keratoconjunctivitis sicca (HP:0001097)3.16067648
29Abnormality of glycolipid metabolism (HP:0010969)3.06355618
30Abnormality of liposaccharide metabolism (HP:0010968)3.06355618
31Abnormality of glycosphingolipid metabolism (HP:0004343)3.06355618
32Abnormality of the heme biosynthetic pathway (HP:0010472)3.05150821
33Chest pain (HP:0100749)3.04504245
34Abnormality of dental color (HP:0011073)3.00954111
35Amyloidosis (HP:0011034)2.99877912
36Chronic mucocutaneous candidiasis (HP:0002728)2.98154175
37Recurrent cutaneous fungal infections (HP:0011370)2.98154175
38Cheilitis (HP:0100825)2.91699570
39Hepatic necrosis (HP:0002605)2.90232257
40Gingival bleeding (HP:0000225)2.89472614
41Panhypogammaglobulinemia (HP:0003139)2.88647180
42Keratoconjunctivitis (HP:0001096)2.88566463
43Gastrointestinal stroma tumor (HP:0100723)2.88068817
44Microcytic anemia (HP:0001935)2.85681338
45Pallor (HP:0000980)2.83962443
46Thrombocytosis (HP:0001894)2.82320627
47Recurrent skin infections (HP:0001581)2.78346762
48Recurrent fungal infections (HP:0002841)2.76793771
49Increased cerebral lipofuscin (HP:0011813)2.74837595
50Recurrent pneumonia (HP:0006532)2.73519814
51Exertional dyspnea (HP:0002875)2.73341957
52Pulmonary infiltrates (HP:0002113)2.71706717
53Elevated erythrocyte sedimentation rate (HP:0003565)2.70001450
54IgM deficiency (HP:0002850)2.69058931
55Recurrent bronchitis (HP:0002837)2.68493403
56Abnormal delayed hypersensitivity skin test (HP:0002963)2.67670583
57Inflammation of the large intestine (HP:0002037)2.65547704
58Increased hepatocellular lipid droplets (HP:0006565)2.63905203
59Mitochondrial inheritance (HP:0001427)2.62831027
60Increased IgM level (HP:0003496)2.62673754
61Peritonitis (HP:0002586)2.62341198
62Myositis (HP:0100614)2.61486455
63Gastrointestinal inflammation (HP:0004386)2.59855794
64Chronic sinusitis (HP:0011109)2.59303228
65Malnutrition (HP:0004395)2.59020140
66Abnormality of macrophages (HP:0004311)2.58435079
67Anorexia (HP:0002039)2.58403000
68Mediastinal lymphadenopathy (HP:0100721)2.57211029
69Macrocytic anemia (HP:0001972)2.56381070
70Leukocytosis (HP:0001974)2.54747719
71Vasculitis (HP:0002633)2.53102121
72Systemic lupus erythematosus (HP:0002725)2.50601583
73Hypergammaglobulinemia (HP:0010702)2.48804190
74Osteomyelitis (HP:0002754)2.47658627
75Recurrent viral infections (HP:0004429)2.45328668
76Loss of speech (HP:0002371)2.44885731
77Prolonged bleeding time (HP:0003010)2.43894316
78Colitis (HP:0002583)2.41272199
79Recurrent lower respiratory tract infections (HP:0002783)2.40715524
80Increased neuronal autofluorescent lipopigment (HP:0002074)2.40342176
81Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.39988626
82Purpura (HP:0000979)2.37636400
83Recurrent gram-negative bacterial infections (HP:0005420)2.36667047
84Type I transferrin isoform profile (HP:0003642)2.33537109
85Arterial thrombosis (HP:0004420)2.28742112
86Lymphopenia (HP:0001888)2.27876986
87Entropion (HP:0000621)2.27603233
88Reduced antithrombin III activity (HP:0001976)2.26899919
89Poikiloderma (HP:0001029)2.26622452
90Aplasia/Hypoplasia of the sacrum (HP:0008517)2.26573240
91Pulmonary embolism (HP:0002204)2.26491965
92Recurrent sinusitis (HP:0011108)2.24675500
93Lipid accumulation in hepatocytes (HP:0006561)2.24611324
94Increased serum ferritin (HP:0003281)2.23226700
95Abnormality of cells of the lymphoid lineage (HP:0012140)2.23077004
96Abnormality of iron homeostasis (HP:0011031)2.22482340
97Papilloma (HP:0012740)2.21510180
98Verrucae (HP:0200043)2.21510180
99Granulocytopenia (HP:0001913)2.20249448
100Erythroderma (HP:0001019)2.20059858
101Urticaria (HP:0001025)2.18644532
102Ectropion (HP:0000656)2.18533019
103Polycythemia (HP:0001901)2.18284930
104Hepatosplenomegaly (HP:0001433)2.17334396
105Absent rod-and cone-mediated responses on ERG (HP:0007688)2.16061332
106Abnormality of the pleura (HP:0002103)2.14760859
107Toxemia of pregnancy (HP:0100603)2.14696186
108Glomerulopathy (HP:0100820)2.11659601
109Small epiphyses (HP:0010585)2.11600814
110Abnormality of T cell physiology (HP:0011840)2.11219052
111Renal Fanconi syndrome (HP:0001994)2.10972929
112Hypothermia (HP:0002045)2.10371182
113Keratitis (HP:0000491)2.09879692
114Acne (HP:0001061)2.09129117
115Premature loss of primary teeth (HP:0006323)2.09081489
116Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.07786440
117Abnormality of T cells (HP:0002843)2.07163903
118Sepsis (HP:0100806)2.06420160
119Abnormal hemoglobin (HP:0011902)2.05819354
120Skin ulcer (HP:0200042)2.05620019
121Increased intramyocellular lipid droplets (HP:0012240)2.04965153
122Abnormality of the peritoneum (HP:0002585)2.04580943
123Spontaneous hematomas (HP:0007420)2.03649612
124Petechiae (HP:0000967)2.02931938
125Interstitial pulmonary disease (HP:0006530)2.02347353
126Autoimmune thrombocytopenia (HP:0001973)2.01459326
127Abnormality of the pericardium (HP:0001697)2.01095609
128Abnormality of the prostate (HP:0008775)2.00942421
129Gangrene (HP:0100758)1.98208386
130Dysostosis multiplex (HP:0000943)1.97703967
131Skin rash (HP:0000988)1.97061334
132Chromosomal breakage induced by crosslinking agents (HP:0003221)1.96884088
133Vertigo (HP:0002321)1.94249764
134Epistaxis (HP:0000421)1.93619939
135Hypoplasia of the capital femoral epiphysis (HP:0003090)1.93496438
136Stomatitis (HP:0010280)1.93077495
137Optic neuritis (HP:0100653)1.92537427
138Retrobulbar optic neuritis (HP:0100654)1.92537427
139Increased CSF lactate (HP:0002490)1.92402654
1403-Methylglutaconic aciduria (HP:0003535)1.91757857
141Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.89131357
142Decreased activity of mitochondrial respiratory chain (HP:0008972)1.89131357
143Acute hepatic failure (HP:0006554)1.88299672
144Arthropathy (HP:0003040)1.88093240
145Thyroiditis (HP:0100646)1.87017202
146Hemoptysis (HP:0002105)1.86587274
147Progressive neurologic deterioration (HP:0002344)1.86453226
148Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.85314979
149Unilateral renal agenesis (HP:0000122)1.85251296
150Neutropenia (HP:0001875)1.84262664
151Abnormality of T cell number (HP:0011839)1.83590318
152Hematochezia (HP:0002573)1.83196480
153Abnormality of the renal collecting system (HP:0004742)1.83041363
154Chromsome breakage (HP:0040012)1.82653895
155Abnormality of polysaccharide metabolism (HP:0011012)1.82411371
156Abnormality of glycosaminoglycan metabolism (HP:0004371)1.82411371
157Abnormality of mucopolysaccharide metabolism (HP:0011020)1.82411371
158Abnormal platelet function (HP:0011869)1.82120454
159Impaired platelet aggregation (HP:0003540)1.82120454
160Increased muscle lipid content (HP:0009058)1.81945151
161True hermaphroditism (HP:0010459)1.81862323

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK14.99128198
2BLK3.67837845
3KIT3.13302768
4TAOK12.71053329
5IRAK42.70418152
6MAP4K12.68513047
7SIK32.42107681
8MAP3K102.32627355
9CASK2.28964150
10BTK2.06824034
11IRAK32.02211793
12SIK21.99801014
13RIPK41.93744667
14NME21.92209126
15TEC1.83974126
16STK161.81623769
17SYK1.71935322
18MKNK21.71652407
19TAOK21.69614169
20FES1.68817443
21CDK191.64074607
22MAP3K11.61511551
23TNIK1.56175502
24TAOK31.54494608
25FGR1.40099866
26CLK11.35674449
27CSF1R1.28800169
28GRK61.25629729
29PTK61.24997907
30TBK11.23490384
31ZAP701.23103227
32MUSK1.22799450
33MAP2K31.21975067
34JAK21.21156987
35CDK81.14208341
36TNK21.13401301
37MAP3K31.12162669
38SIK11.12064850
39BCKDK1.09767179
40SRPK11.08535842
41MARK31.08534589
42TYK21.08437465
43IRAK11.08302757
44YES11.07789929
45STK241.06830129
46ERN11.06723954
47PRKG21.06594449
48LYN1.06017786
49TXK1.05697875
50VRK11.01160770
51NLK1.01032249
52IRAK20.97202550
53PRKD20.96200517
54PRPF4B0.94335692
55IKBKE0.92502054
56MAPK40.92398924
57MATK0.92108507
58MARK20.91050736
59ADRBK20.91003217
60SMG10.90178387
61JAK10.89518930
62KSR20.88879586
63MAP2K70.85602158
64NEK90.84789006
65GRK70.83675221
66HCK0.83620487
67ACVR1B0.83498908
68MKNK10.82952931
69GRK10.81470143
70IKBKB0.81207514
71MAPKAPK30.79855626
72DAPK20.78896931
73EIF2AK30.78499882
74RIPK10.77386855
75MAP3K120.76922417
76TGFBR20.76026500
77PDPK10.75655581
78LCK0.74538754
79TESK10.74451327
80EPHB10.73666593
81PTK2B0.73177596
82LRRK20.73018650
83DYRK30.72849106
84RPS6KL10.71604249
85RPS6KC10.71604249
86MAP3K20.71356524
87MAP3K50.70633567
88PDK10.69029302
89CDK40.67057811
90MAPK110.66069457
91MAPKAPK50.65067117
92MAP3K110.64516519
93PKN10.63983345
94CSK0.62810667
95FYN0.62645273
96DYRK1B0.62336526
97RPS6KA50.61995894
98CDC42BPA0.61473153
99RPS6KA60.61207669
100ITK0.61019652
101MYLK0.60435393
102PIM20.60350178
103PHKG10.59759817
104PHKG20.59759817
105EPHA30.58663173
106STK40.58577213
107ILK0.58247083
108MAP2K60.57690842
109HIPK20.56100420
110MAP3K140.54699253
111PIM10.53976239
112RPS6KA20.53941355
113MAPK70.53712279
114MAP3K130.53150507
115TRIB30.52357285
116MAPKAPK20.52007332
117STK110.51098115
118MAP2K20.50878567
119JAK30.50820501
120STK380.50565503
121PRKCQ0.49692932
122BRAF0.49539797
123CDK90.46561300
124FLT30.46542038
125KDR0.45275449
126STK100.41082068
127TESK20.40538205
128MAPK120.40187132
129PRKCZ0.39938555
130DAPK30.39663845
131MAP3K70.39631230
132BUB10.39098249
133BMX0.38898085
134MAP2K40.38498350
135FGFR40.38349144
136MAP3K60.38202482
137MST40.37561181
138CAMK10.37341224
139CSNK1G10.36673976
140PRKCD0.35697850
141EIF2AK20.35455894
142RET0.35156943
143MAP3K80.35072125
144PRKD10.31579807

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.87171110
2Primary immunodeficiency_Homo sapiens_hsa053403.11331141
3DNA replication_Homo sapiens_hsa030302.95598104
4Homologous recombination_Homo sapiens_hsa034402.95041300
5Other glycan degradation_Homo sapiens_hsa005112.57343563
6Allograft rejection_Homo sapiens_hsa053302.44941894
7Graft-versus-host disease_Homo sapiens_hsa053322.39896369
8B cell receptor signaling pathway_Homo sapiens_hsa046622.31608376
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.29824629
10Autoimmune thyroid disease_Homo sapiens_hsa053202.26391339
11Base excision repair_Homo sapiens_hsa034102.11774067
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.10514702
13RNA polymerase_Homo sapiens_hsa030202.03458220
14Protein export_Homo sapiens_hsa030601.98654620
15Sulfur relay system_Homo sapiens_hsa041221.89089850
16Hematopoietic cell lineage_Homo sapiens_hsa046401.87416395
17Type I diabetes mellitus_Homo sapiens_hsa049401.85883915
18Oxidative phosphorylation_Homo sapiens_hsa001901.83834287
19Mismatch repair_Homo sapiens_hsa034301.83340383
20Fanconi anemia pathway_Homo sapiens_hsa034601.82518637
21Leishmaniasis_Homo sapiens_hsa051401.81269699
22NF-kappa B signaling pathway_Homo sapiens_hsa040641.66323472
23Non-homologous end-joining_Homo sapiens_hsa034501.65928619
24Nucleotide excision repair_Homo sapiens_hsa034201.62329524
25Glycosaminoglycan degradation_Homo sapiens_hsa005311.62001827
26Sphingolipid metabolism_Homo sapiens_hsa006001.58943382
27Intestinal immune network for IgA production_Homo sapiens_hsa046721.53644585
28Parkinsons disease_Homo sapiens_hsa050121.50040873
29Viral myocarditis_Homo sapiens_hsa054161.44842386
30Pyrimidine metabolism_Homo sapiens_hsa002401.44694447
31Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.39137256
32Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.36827188
33Toll-like receptor signaling pathway_Homo sapiens_hsa046201.33019139
34RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.32776318
35Leukocyte transendothelial migration_Homo sapiens_hsa046701.29923398
36Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.27447039
37Tuberculosis_Homo sapiens_hsa051521.26526896
38Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.25148567
39Osteoclast differentiation_Homo sapiens_hsa043801.23957864
40Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.21530169
41Systemic lupus erythematosus_Homo sapiens_hsa053221.20407986
42TNF signaling pathway_Homo sapiens_hsa046681.20188469
43Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.18342977
44Alzheimers disease_Homo sapiens_hsa050101.17751421
45Hepatitis C_Homo sapiens_hsa051601.14328949
46Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.12497100
47Malaria_Homo sapiens_hsa051441.12491622
48NOD-like receptor signaling pathway_Homo sapiens_hsa046211.10298199
49Measles_Homo sapiens_hsa051621.08634605
50Carbohydrate digestion and absorption_Homo sapiens_hsa049731.06151689
51Lysosome_Homo sapiens_hsa041421.03536945
52Transcriptional misregulation in cancer_Homo sapiens_hsa052021.02966390
53Pertussis_Homo sapiens_hsa051331.01502539
54Herpes simplex infection_Homo sapiens_hsa051681.00369296
55Spliceosome_Homo sapiens_hsa030400.99733047
56Staphylococcus aureus infection_Homo sapiens_hsa051500.98421851
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.97814319
58Acute myeloid leukemia_Homo sapiens_hsa052210.97683834
59SNARE interactions in vesicular transport_Homo sapiens_hsa041300.96325832
60Huntingtons disease_Homo sapiens_hsa050160.93629291
61Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.93000629
62Glycerophospholipid metabolism_Homo sapiens_hsa005640.88615099
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.86533162
64Endocytosis_Homo sapiens_hsa041440.85762330
65Non-small cell lung cancer_Homo sapiens_hsa052230.84452973
66Fatty acid elongation_Homo sapiens_hsa000620.84384533
67Proteasome_Homo sapiens_hsa030500.81570693
68Jak-STAT signaling pathway_Homo sapiens_hsa046300.81536332
69Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.79175202
70Arachidonic acid metabolism_Homo sapiens_hsa005900.78769361
71Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.77459013
72Pancreatic cancer_Homo sapiens_hsa052120.77448433
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.76162867
74Histidine metabolism_Homo sapiens_hsa003400.75263688
75Purine metabolism_Homo sapiens_hsa002300.74953031
76Folate biosynthesis_Homo sapiens_hsa007900.74263029
77Adipocytokine signaling pathway_Homo sapiens_hsa049200.73063405
78Chronic myeloid leukemia_Homo sapiens_hsa052200.70172501
79VEGF signaling pathway_Homo sapiens_hsa043700.69947414
80Galactose metabolism_Homo sapiens_hsa000520.67839652
81Fructose and mannose metabolism_Homo sapiens_hsa000510.67710369
82Basal transcription factors_Homo sapiens_hsa030220.66522610
83Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.66386495
84Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.65765177
85Phagosome_Homo sapiens_hsa041450.64495729
86Epstein-Barr virus infection_Homo sapiens_hsa051690.64163594
87Olfactory transduction_Homo sapiens_hsa047400.63219492
88Vitamin digestion and absorption_Homo sapiens_hsa049770.62999738
89Amoebiasis_Homo sapiens_hsa051460.62836115
90Antigen processing and presentation_Homo sapiens_hsa046120.62000013
91Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.58536920
92Collecting duct acid secretion_Homo sapiens_hsa049660.58068163
93Notch signaling pathway_Homo sapiens_hsa043300.57442047
94Hepatitis B_Homo sapiens_hsa051610.56061690
95Asthma_Homo sapiens_hsa053100.55990822
96Apoptosis_Homo sapiens_hsa042100.53056458
97Shigellosis_Homo sapiens_hsa051310.52972630
98Prolactin signaling pathway_Homo sapiens_hsa049170.52569210
99Chemokine signaling pathway_Homo sapiens_hsa040620.51133262
100Salmonella infection_Homo sapiens_hsa051320.50949797
101Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.50740818
102Insulin resistance_Homo sapiens_hsa049310.49979657
103Mineral absorption_Homo sapiens_hsa049780.48736948
104N-Glycan biosynthesis_Homo sapiens_hsa005100.46827200
105African trypanosomiasis_Homo sapiens_hsa051430.46575539
106Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.46283946
107Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.45188487
108Fat digestion and absorption_Homo sapiens_hsa049750.43695063
109Influenza A_Homo sapiens_hsa051640.43356633
110Legionellosis_Homo sapiens_hsa051340.43287111
111Neurotrophin signaling pathway_Homo sapiens_hsa047220.42654076
112Phospholipase D signaling pathway_Homo sapiens_hsa040720.41056936
113Rheumatoid arthritis_Homo sapiens_hsa053230.39946056
114Renin-angiotensin system_Homo sapiens_hsa046140.39441697
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.39033485
116Platelet activation_Homo sapiens_hsa046110.38716355
117Cyanoamino acid metabolism_Homo sapiens_hsa004600.38641325
118Phosphatidylinositol signaling system_Homo sapiens_hsa040700.38470526
119AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.38307834
120T cell receptor signaling pathway_Homo sapiens_hsa046600.38137576
121Steroid biosynthesis_Homo sapiens_hsa001000.37956090
122Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.37782595
123Renal cell carcinoma_Homo sapiens_hsa052110.37571299
124Toxoplasmosis_Homo sapiens_hsa051450.37495169
125GnRH signaling pathway_Homo sapiens_hsa049120.36860905
126Sulfur metabolism_Homo sapiens_hsa009200.36646330
127Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.35291199
128FoxO signaling pathway_Homo sapiens_hsa040680.34883671
129Peroxisome_Homo sapiens_hsa041460.34765049
130alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.34384510
131Metabolic pathways_Homo sapiens_hsa011000.33112656
132Pentose phosphate pathway_Homo sapiens_hsa000300.32843174
133Alcoholism_Homo sapiens_hsa050340.32424187
134Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.30673729
135Cell cycle_Homo sapiens_hsa041100.29066650
136Drug metabolism - other enzymes_Homo sapiens_hsa009830.28491146
137Regulation of autophagy_Homo sapiens_hsa041400.27741375
138Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.27699805
139Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.27435415
140Pentose and glucuronate interconversions_Homo sapiens_hsa000400.26811884
141beta-Alanine metabolism_Homo sapiens_hsa004100.26105254

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