B3GNT9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)6.68612048
2central nervous system myelination (GO:0022010)6.68612048
3protein heterotrimerization (GO:0070208)6.36505151
4bone trabecula formation (GO:0060346)5.75267237
5collagen fibril organization (GO:0030199)5.74088586
6axon ensheathment (GO:0008366)4.94844254
7ensheathment of neurons (GO:0007272)4.94844254
8myelination (GO:0042552)4.85925871
9skin morphogenesis (GO:0043589)4.69827596
10virion attachment to host cell (GO:0019062)4.60757429
11adhesion of symbiont to host cell (GO:0044650)4.60757429
12fatty acid elongation (GO:0030497)4.38004959
13regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.35919581
14response to redox state (GO:0051775)4.29060781
15extracellular matrix assembly (GO:0085029)4.14284028
16type B pancreatic cell proliferation (GO:0044342)4.12093923
17extracellular fibril organization (GO:0043206)4.09060408
18COPI coating of Golgi vesicle (GO:0048205)4.04016867
19Golgi transport vesicle coating (GO:0048200)4.04016867
20collagen catabolic process (GO:0030574)4.01202114
21collagen metabolic process (GO:0032963)3.99070211
22regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.93561140
23protein retention in ER lumen (GO:0006621)3.91729253
24chondrocyte development (GO:0002063)3.88485765
25chondrocyte proliferation (GO:0035988)3.87875824
26signal peptide processing (GO:0006465)3.78125080
27maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.75739918
28negative regulation of neurotransmitter secretion (GO:0046929)3.74634621
29craniofacial suture morphogenesis (GO:0097094)3.73140275
30peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.71576120
31multicellular organismal macromolecule metabolic process (GO:0044259)3.71381453
32long-chain fatty acid biosynthetic process (GO:0042759)3.69320306
33multicellular organismal catabolic process (GO:0044243)3.68647986
34mesenchymal-epithelial cell signaling (GO:0060638)3.66918136
35cell adhesion mediated by integrin (GO:0033627)3.66126598
36cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.59497626
37planar cell polarity pathway involved in neural tube closure (GO:0090179)3.59168315
38sequestering of extracellular ligand from receptor (GO:0035581)3.53938763
39myelination in peripheral nervous system (GO:0022011)3.52592626
40peripheral nervous system axon ensheathment (GO:0032292)3.52592626
41cranial suture morphogenesis (GO:0060363)3.48982586
42multicellular organismal metabolic process (GO:0044236)3.46188441
43short-term memory (GO:0007614)3.45341506
44basement membrane organization (GO:0071711)3.44501529
45adhesion of symbiont to host (GO:0044406)3.40854419
46vascular endothelial growth factor signaling pathway (GO:0038084)3.38548920
47positive regulation of blood vessel endothelial cell migration (GO:0043536)3.33771071
48fibril organization (GO:0097435)3.32716845
49barbed-end actin filament capping (GO:0051016)3.30825990
50venous blood vessel morphogenesis (GO:0048845)3.29722129
51regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.29277151
52cell-substrate junction assembly (GO:0007044)3.28320781
53tooth mineralization (GO:0034505)3.25875483
54apoptotic cell clearance (GO:0043277)3.22507085
55import into cell (GO:0098657)3.21852584
56negative regulation of smooth muscle cell migration (GO:0014912)3.21406157
57stress fiber assembly (GO:0043149)3.19435189
58negative regulation of chondrocyte differentiation (GO:0032331)3.18369177
59retina vasculature morphogenesis in camera-type eye (GO:0061299)3.17914974
60hemidesmosome assembly (GO:0031581)3.16416809
61negative regulation of neurotransmitter transport (GO:0051589)3.14049564
62substrate-dependent cell migration (GO:0006929)3.12010862
63dermatan sulfate biosynthetic process (GO:0030208)3.11342963
64extracellular matrix disassembly (GO:0022617)3.11278680
65myelin maintenance (GO:0043217)3.10151531
66regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.07036703
67negative regulation of JUN kinase activity (GO:0043508)3.05426343
68keratan sulfate catabolic process (GO:0042340)3.04846136
69negative regulation of fatty acid transport (GO:2000192)3.01165464
70cellular response to vitamin (GO:0071295)2.99540989
71endodermal cell differentiation (GO:0035987)2.98485215
72limb bud formation (GO:0060174)2.96288819
73glomerular filtration (GO:0003094)2.95253230
74embryonic cranial skeleton morphogenesis (GO:0048701)2.92175800
75chondroitin sulfate biosynthetic process (GO:0030206)2.89664298
76vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.88388172
77blood vessel maturation (GO:0001955)2.88305262
78peptidyl-proline hydroxylation (GO:0019511)2.87562397
79protein localization to endosome (GO:0036010)2.87550488
80extracellular matrix organization (GO:0030198)2.85983905
81positive regulation of endothelial cell apoptotic process (GO:2000353)2.85626793
82cell migration involved in sprouting angiogenesis (GO:0002042)2.85394418
83photoreceptor cell differentiation (GO:0046530)2.84440667
84eye photoreceptor cell differentiation (GO:0001754)2.84440667
85extracellular structure organization (GO:0043062)2.84429139
86metanephric mesenchyme development (GO:0072075)2.84178453
87negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)2.84055761
88astrocyte development (GO:0014002)2.82853714
89dermatan sulfate metabolic process (GO:0030205)2.82409699
90positive regulation of osteoblast proliferation (GO:0033690)2.82370126
91glomerular basement membrane development (GO:0032836)2.81520345
92endocardial cushion development (GO:0003197)2.81499233
93negative regulation of protein localization to cell surface (GO:2000009)2.79964927
94negative regulation of glucose import (GO:0046325)2.79571134
95adherens junction assembly (GO:0034333)2.78467670
96cholesterol biosynthetic process (GO:0006695)2.78414554
97smooth muscle tissue development (GO:0048745)2.78294481
98regulation of collateral sprouting (GO:0048670)2.77625370
99hyaluronan catabolic process (GO:0030214)2.76776550
100creatine metabolic process (GO:0006600)2.74163402
101apical protein localization (GO:0045176)2.74078737
102focal adhesion assembly (GO:0048041)2.73724151
103cell-substrate adherens junction assembly (GO:0007045)2.73724151
104regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.73578877
105trabecula formation (GO:0060343)2.73218271
106oligodendrocyte differentiation (GO:0048709)2.71511322
107negative regulation of catenin import into nucleus (GO:0035414)2.71197078
108positive regulation of extracellular matrix organization (GO:1903055)2.70482089
109kidney mesenchyme development (GO:0072074)2.68479805
110Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.68120369
111protein hydroxylation (GO:0018126)2.67625806
112positive regulation of receptor recycling (GO:0001921)2.66768626
113cellular response to vitamin D (GO:0071305)2.66127234
114cortical cytoskeleton organization (GO:0030865)2.65384032
115regulation of early endosome to late endosome transport (GO:2000641)2.65120514
116cortical actin cytoskeleton organization (GO:0030866)2.62656592
117heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.62537256
118endothelial cell chemotaxis (GO:0035767)2.62432561
119positive regulation of axon extension (GO:0045773)2.62390111
120positive regulation of oligodendrocyte differentiation (GO:0048714)2.62367606
121wound healing, spreading of epidermal cells (GO:0035313)2.61152921
122embryo implantation (GO:0007566)2.60454678
123asymmetric protein localization (GO:0008105)2.60410165
124epithelial cell-cell adhesion (GO:0090136)2.60056646
125retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.59760991
126substantia nigra development (GO:0021762)2.59310585
127regulation of integrin-mediated signaling pathway (GO:2001044)2.58539061
128regulation of glucocorticoid metabolic process (GO:0031943)2.58433149
129mesenchymal cell proliferation (GO:0010463)2.58158520
130camera-type eye morphogenesis (GO:0048593)2.57119272
131regulation of osteoblast proliferation (GO:0033688)2.56785155
132middle ear morphogenesis (GO:0042474)2.56150916
133negative regulation of epithelial to mesenchymal transition (GO:0010719)2.55764513
134regulation of type B pancreatic cell apoptotic process (GO:2000674)2.55729567
135interleukin-6-mediated signaling pathway (GO:0070102)2.54944956
136negative regulation of osteoblast proliferation (GO:0033689)2.54301709
137response to methylmercury (GO:0051597)2.54162519
138cell migration involved in heart development (GO:0060973)2.53935349
139regulation of establishment of planar polarity (GO:0090175)2.53884354
140mesenchyme morphogenesis (GO:0072132)2.53668431
141dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.52918333
142regulation of extracellular matrix disassembly (GO:0010715)2.52284288
143cellular response to hepatocyte growth factor stimulus (GO:0035729)2.52005198
144response to hepatocyte growth factor (GO:0035728)2.52005198
145cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.51490254
146regulation of apoptotic process involved in morphogenesis (GO:1902337)2.51178957
147negative regulation of embryonic development (GO:0045992)2.50770164
148desmosome organization (GO:0002934)2.50590595
149endocytic recycling (GO:0032456)2.50429796
150glial cell migration (GO:0008347)2.50411128
151renal filtration (GO:0097205)2.50263638
152cellular response to amino acid stimulus (GO:0071230)2.50165230
153endochondral ossification (GO:0001958)2.49402104
154replacement ossification (GO:0036075)2.49402104
155chondroitin sulfate catabolic process (GO:0030207)2.48195241
156endothelial cell morphogenesis (GO:0001886)2.46258244
157cardiac epithelial to mesenchymal transition (GO:0060317)2.45083305
158regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.42535807
159extracellular regulation of signal transduction (GO:1900115)2.42075694
160extracellular negative regulation of signal transduction (GO:1900116)2.42075694

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human6.20457764
2PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.47286276
3WT1_19549856_ChIP-ChIP_CCG9911_Human3.26595283
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.06416023
5EED_16625203_ChIP-ChIP_MESCs_Mouse2.92208681
6THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.67124034
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.54418434
8TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.52580781
9SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.48632140
10* EZH2_27304074_Chip-Seq_ESCs_Mouse2.40871323
11ELK3_25401928_ChIP-Seq_HUVEC_Human2.40303041
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.39224981
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.39224981
14SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.33178285
15PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.32900312
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.30728707
17SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.29911699
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.29545957
19NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.24427109
20JARID2_20064375_ChIP-Seq_MESCs_Mouse2.23982064
21ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.23207568
22SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.14787889
23CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.11990086
24LXR_22292898_ChIP-Seq_THP-1_Human2.09893648
25TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.07425091
26RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.06270294
27JARID2_20075857_ChIP-Seq_MESCs_Mouse2.04479111
28CDX2_19796622_ChIP-Seq_MESCs_Mouse1.97577331
29MTF2_20144788_ChIP-Seq_MESCs_Mouse1.95984305
30ESR2_21235772_ChIP-Seq_MCF-7_Human1.94367994
31SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.94338540
32NRF2_20460467_ChIP-Seq_MEFs_Mouse1.92701090
33NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.92701090
34GBX2_23144817_ChIP-Seq_PC3_Human1.91126310
35RACK7_27058665_Chip-Seq_MCF-7_Human1.90650541
36RARG_19884340_ChIP-ChIP_MEFs_Mouse1.85848306
37EP300_21415370_ChIP-Seq_HL-1_Mouse1.84796316
38CJUN_26792858_Chip-Seq_BT549_Human1.83939857
39AR_21572438_ChIP-Seq_LNCaP_Human1.82556626
40WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.73008082
41RNF2_27304074_Chip-Seq_ESCs_Mouse1.71146513
42P300_27058665_Chip-Seq_ZR-75-30cells_Human1.70493147
43HIF1A_21447827_ChIP-Seq_MCF-7_Human1.67930916
44UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.67059629
45VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.64072991
46ER_23166858_ChIP-Seq_MCF-7_Human1.62765278
47* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.62619498
48CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.61187030
49EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.60059796
50KDM2B_26808549_Chip-Seq_SUP-B15_Human1.58014063
51RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.56561259
52* EZH2_27294783_Chip-Seq_ESCs_Mouse1.56342323
53KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.54137009
54CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.53553708
55OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.52939483
56* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.47652090
57ESR1_21235772_ChIP-Seq_MCF-7_Human1.47400660
58SMAD_19615063_ChIP-ChIP_OVARY_Human1.46795113
59* KDM2B_26808549_Chip-Seq_K562_Human1.45717791
60TBX20_22080862_ChIP-Seq_HEART_Mouse1.45194521
61TBX20_22328084_ChIP-Seq_HEART_Mouse1.45194521
62MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.44929552
63NFIB_24661679_ChIP-Seq_LUNG_Mouse1.44697019
64STAT6_21828071_ChIP-Seq_BEAS2B_Human1.41775079
65SOX9_24532713_ChIP-Seq_HFSC_Mouse1.41666657
66SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.41319027
67TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.41089603
68PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.40921102
69KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.38039891
70SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.37480816
71SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.37480816
72TP53_20018659_ChIP-ChIP_R1E_Mouse1.36726648
73ZNF263_19887448_ChIP-Seq_K562_Human1.35397687
74ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.34950226
75NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.34574850
76CLOCK_20551151_ChIP-Seq_293T_Human1.34195861
77PIAS1_25552417_ChIP-Seq_VCAP_Human1.33512093
78EGR1_19374776_ChIP-ChIP_THP-1_Human1.32848473
79SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.31162864
80HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.31080873
81EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26984928
82* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.26717185
83TP53_18474530_ChIP-ChIP_U2OS_Human1.25537899
84ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.24977393
85* ATF3_27146783_Chip-Seq_COLON_Human1.24398329
86TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.23610195
87PPAR_26484153_Chip-Seq_NCI-H1993_Human1.23356758
88CBX2_27304074_Chip-Seq_ESCs_Mouse1.21797912
89* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.21740908
90TET1_21490601_ChIP-Seq_MESCs_Mouse1.20949331
91ERG_21242973_ChIP-ChIP_JURKAT_Human1.19318349
92SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.17799572
93KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.17122434
94ZFP281_18757296_ChIP-ChIP_E14_Mouse1.15869771
95NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.15089713
96TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15009691
97RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.13966700
98TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13647304
99EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.13633554
100SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.13615954
101SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.11548987
102BRD4_25478319_ChIP-Seq_HGPS_Human1.10962718
103HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.10355206
104BMI1_23680149_ChIP-Seq_NPCS_Mouse1.10317520
105KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.09374507
106KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.09374507
107KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.09374507
108PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.07766643
109EOMES_21245162_ChIP-Seq_HESCs_Human1.07423062
110* SA1_22415368_ChIP-Seq_MEFs_Mouse1.06992555
111DROSHA_22980978_ChIP-Seq_HELA_Human1.06701963
112KDM2B_26808549_Chip-Seq_DND41_Human1.06402575
113TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.05495913
114ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.04638940
115SMC3_22415368_ChIP-Seq_MEFs_Mouse1.03190329
116SOX2_20726797_ChIP-Seq_SW620_Human1.02206947
117SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.01086892
118NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.00907791
119ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.00323530
120JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99972925
121DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.99822041
122ZFP57_27257070_Chip-Seq_ESCs_Mouse0.99650818
123TP63_17297297_ChIP-ChIP_HaCaT_Human0.98789219
124ZFP281_27345836_Chip-Seq_ESCs_Mouse0.97711145
125RAD21_21589869_ChIP-Seq_MESCs_Mouse0.97369896
126CTBP1_25329375_ChIP-Seq_LNCAP_Human0.97291604
127TP53_23651856_ChIP-Seq_MEFs_Mouse0.96937139
128SA1_27219007_Chip-Seq_ERYTHROID_Human0.96877032
129KDM2B_26808549_Chip-Seq_JURKAT_Human0.96659828
130TP53_16413492_ChIP-PET_HCT116_Human0.95934697
131OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.94212788
132RING1B_27294783_Chip-Seq_NPCs_Mouse0.93391063
133* RING1B_27294783_Chip-Seq_ESCs_Mouse0.92790025
134ISL1_27105846_Chip-Seq_CPCs_Mouse0.90535631
135SMAD3_21741376_ChIP-Seq_EPCs_Human0.90249359
136TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.89215866
137STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.88463076
138EZH2_22144423_ChIP-Seq_EOC_Human0.88353485
139FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.88212019
140ZNF217_24962896_ChIP-Seq_MCF-7_Human0.87223874
141WT1_25993318_ChIP-Seq_PODOCYTE_Human0.86589428
142POU5F1_16153702_ChIP-ChIP_HESCs_Human0.85740803
143ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.84912160
144CTBP2_25329375_ChIP-Seq_LNCAP_Human0.84280428
145TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.82667863
146PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.81368257
147ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.80958752
148UBF1/2_26484160_Chip-Seq_HMECs_Human0.80593874
149JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.79737836
150GATA2_21666600_ChIP-Seq_HMVEC_Human0.79211707
151POU3F2_20337985_ChIP-ChIP_501MEL_Human0.78710955
152PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.77825165
153TP53_22127205_ChIP-Seq_IMR90_Human0.77581245
154DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.77510484

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen8.40744657
2MP0005503_abnormal_tendon_morphology6.38976408
3MP0005275_abnormal_skin_tensile4.52058588
4MP0004272_abnormal_basement_membrane2.76577561
5MP0003279_aneurysm2.57875300
6MP0003950_abnormal_plasma_membrane2.51879326
7MP0001958_emphysema2.43988553
8MP0001542_abnormal_bone_strength2.39059609
9MP0005623_abnormal_meninges_morphology2.38183289
10MP0009384_cardiac_valve_regurgitation2.37050249
11MP0000920_abnormal_myelination2.36201731
12MP0002108_abnormal_muscle_morphology2.33449111
13MP0005508_abnormal_skeleton_morphology2.30228496
14MP0005257_abnormal_intraocular_pressure2.26106621
15MP0009250_abnormal_appendicular_skeleto2.10674156
16MP0004134_abnormal_chest_morphology2.08717917
17MP0009780_abnormal_chondrocyte_physiolo2.00993624
18MP0002295_abnormal_pulmonary_circulatio1.92126460
19MP0006054_spinal_hemorrhage1.87979175
20MP0001299_abnormal_eye_distance/1.84587495
21MP0003385_abnormal_body_wall1.68668167
22MP0000013_abnormal_adipose_tissue1.66921449
23MP0002060_abnormal_skin_morphology1.63114117
24MP0003705_abnormal_hypodermis_morpholog1.62290789
25MP0002933_joint_inflammation1.60443871
26MP0000462_abnormal_digestive_system1.59802774
27MP0004185_abnormal_adipocyte_glucose1.58167693
28MP0010030_abnormal_orbit_morphology1.56370814
29MP0005171_absent_coat_pigmentation1.53386209
30MP0010352_gastrointestinal_tract_polyps1.52287548
31MP0005058_abnormal_lysosome_morphology1.50817645
32MP0002896_abnormal_bone_mineralization1.47863388
33MP0004858_abnormal_nervous_system1.46862295
34MP0000762_abnormal_tongue_morphology1.38937787
35MP0000163_abnormal_cartilage_morphology1.35140114
36MP0000428_abnormal_craniofacial_morphol1.34378351
37MP0001243_abnormal_dermal_layer1.33968479
38MP0000003_abnormal_adipose_tissue1.33430166
39MP0000751_myopathy1.29999238
40MP0001661_extended_life_span1.27199718
41MP0002115_abnormal_skeleton_extremities1.26521219
42MP0001346_abnormal_lacrimal_gland1.22537581
43MP0005390_skeleton_phenotype1.21040976
44MP0009840_abnormal_foam_cell1.20723894
45MP0001348_abnormal_lacrimal_gland1.18475085
46MP0001849_ear_inflammation1.14087767
47MP0003937_abnormal_limbs/digits/tail_de1.13843155
48MP0003283_abnormal_digestive_organ1.12430040
49MP0003122_maternal_imprinting1.11868962
50MP0003755_abnormal_palate_morphology1.11090689
51MP0003300_gastrointestinal_ulcer1.10982636
52MP0002877_abnormal_melanocyte_morpholog1.07013094
53MP0000733_abnormal_muscle_development1.06032398
54MP0002932_abnormal_joint_morphology1.05079580
55MP0000681_abnormal_thyroid_gland1.03081416
56MP0004742_abnormal_vestibular_system1.02210012
57MP0002998_abnormal_bone_remodeling1.00840782
58MP0002282_abnormal_trachea_morphology0.99312891
59MP0003941_abnormal_skin_development0.99050283
60MP0003091_abnormal_cell_migration0.99016369
61MP0000613_abnormal_salivary_gland0.96092706
62MP0003634_abnormal_glial_cell0.95555372
63MP0002113_abnormal_skeleton_development0.95420717
64MP0000049_abnormal_middle_ear0.93633830
65MP0000534_abnormal_ureter_morphology0.91912572
66MP0005595_abnormal_vascular_smooth0.91174789
67MP0005023_abnormal_wound_healing0.90786639
68MP0010368_abnormal_lymphatic_system0.90153998
69MP0004145_abnormal_muscle_electrophysio0.89126702
70MP0000749_muscle_degeneration0.88848642
71MP0009379_abnormal_foot_pigmentation0.86328429
72MP0005164_abnormal_response_to0.86034662
73MP0002133_abnormal_respiratory_system0.82963102
74MP0005388_respiratory_system_phenotype0.82963102
75MP0006072_abnormal_retinal_apoptosis0.82352449
76MP0003795_abnormal_bone_structure0.81991183
77MP0001188_hyperpigmentation0.81978225
78MP0005375_adipose_tissue_phenotype0.81556054
79MP0001879_abnormal_lymphatic_vessel0.80687123
80MP0004510_myositis0.79622818
81MP0005165_increased_susceptibility_to0.79532875
82MP0002116_abnormal_craniofacial_bone0.79226997
83MP0000432_abnormal_head_morphology0.79003687
84MP0005369_muscle_phenotype0.78612255
85MP0001177_atelectasis0.78544971
86MP0002109_abnormal_limb_morphology0.78024542
87MP0003935_abnormal_craniofacial_develop0.77943693
88MP0010386_abnormal_urinary_bladder0.77816221
89MP0003172_abnormal_lysosome_physiology0.77079980
90MP0001340_abnormal_eyelid_morphology0.76920790
91MP0003942_abnormal_urinary_system0.76545304
92MP0000750_abnormal_muscle_regeneration0.76463133
93MP0000467_abnormal_esophagus_morphology0.76383102
94MP0002114_abnormal_axial_skeleton0.75986406
95MP0002249_abnormal_larynx_morphology0.75454584
96MP0005076_abnormal_cell_differentiation0.74260798
97MP0002128_abnormal_blood_circulation0.72409089
98MP0002233_abnormal_nose_morphology0.70772423
99MP0003448_altered_tumor_morphology0.70556170
100MP0005409_darkened_coat_color0.70381366
101MP0001614_abnormal_blood_vessel0.69354495
102MP0003191_abnormal_cellular_cholesterol0.68841009
103MP0000767_abnormal_smooth_muscle0.68704459
104MP0000747_muscle_weakness0.68307182
105MP0001533_abnormal_skeleton_physiology0.67378153
106MP0000759_abnormal_skeletal_muscle0.67280301
107MP0003938_abnormal_ear_development0.67255405
108MP0009053_abnormal_anal_canal0.67241831
109MP0003045_fibrosis0.66893571
110MP0002177_abnormal_outer_ear0.66705049
111MP0005197_abnormal_uvea_morphology0.66399255
112MP0001175_abnormal_lung_morphology0.66291352
113MP0008775_abnormal_heart_ventricle0.65525009
114MP0003566_abnormal_cell_adhesion0.64570920
115MP0003329_amyloid_beta_deposits0.62450318
116MP0003453_abnormal_keratinocyte_physiol0.61672275
117MP0000343_altered_response_to0.60946721
118MP0000538_abnormal_urinary_bladder0.59924200
119MP0004233_abnormal_muscle_weight0.59871016
120MP0002254_reproductive_system_inflammat0.59624947
121MP0000778_abnormal_nervous_system0.59584996
122MP0002089_abnormal_postnatal_growth/wei0.59558943
123MP0002168_other_aberrant_phenotype0.59377457
124MP0001270_distended_abdomen0.59033823
125MP0010771_integument_phenotype0.58813383
126MP0003115_abnormal_respiratory_system0.58126910
127MP0003195_calcinosis0.58018468
128MP0002938_white_spotting0.57890361
129MP0005330_cardiomyopathy0.57322500
130MP0001915_intracranial_hemorrhage0.56956098
131MP0005220_abnormal_exocrine_pancreas0.56792857
132MP0008004_abnormal_stomach_pH0.56464412
133MP0001905_abnormal_dopamine_level0.53922787

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)8.79797815
2Protrusio acetabuli (HP:0003179)7.61367402
3Soft skin (HP:0000977)5.14525516
4Aortic dissection (HP:0002647)4.27475987
5Ankle contracture (HP:0006466)4.22162538
6Broad metatarsal (HP:0001783)4.21870578
7Follicular hyperkeratosis (HP:0007502)4.11355011
8Abnormality of dentin (HP:0010299)4.09275389
9Atrophic scars (HP:0001075)3.87695389
10Shallow orbits (HP:0000586)3.86885124
11Bladder diverticulum (HP:0000015)3.65236259
12Vertebral compression fractures (HP:0002953)3.64144656
13Neonatal short-limb short stature (HP:0008921)3.63909192
14Wormian bones (HP:0002645)3.59601177
15Fragile skin (HP:0001030)3.57460273
16Peritonitis (HP:0002586)3.42931353
17Biconcave vertebral bodies (HP:0004586)3.22884489
18Blue sclerae (HP:0000592)3.20887451
19Cervical subluxation (HP:0003308)3.16515503
20Hyperextensible skin (HP:0000974)3.14642308
21Type 1 muscle fiber predominance (HP:0003803)3.08085192
22Genu recurvatum (HP:0002816)3.04755682
23Spinal rigidity (HP:0003306)2.97964078
24Bowel diverticulosis (HP:0005222)2.94179865
25Increased variability in muscle fiber diameter (HP:0003557)2.91861776
26Slender build (HP:0001533)2.86790028
27Abnormal delivery (HP:0001787)2.82802434
28Infantile muscular hypotonia (HP:0008947)2.81194094
29Coronal craniosynostosis (HP:0004440)2.79960478
30Mild short stature (HP:0003502)2.70355216
31Short nail (HP:0001799)2.67557137
32Osteoarthritis (HP:0002758)2.65544026
33Aortic regurgitation (HP:0001659)2.60543646
34Bell-shaped thorax (HP:0001591)2.59377913
35Cardiovascular calcification (HP:0011915)2.53654641
36Wide anterior fontanel (HP:0000260)2.50205234
37Joint stiffness (HP:0001387)2.50085149
38Mitral valve prolapse (HP:0001634)2.49540925
39Small epiphyses (HP:0010585)2.47164240
40Aneurysm (HP:0002617)2.44416569
41Sensory axonal neuropathy (HP:0003390)2.42547805
42Mitral stenosis (HP:0001718)2.42459937
43Broad ribs (HP:0000885)2.39916308
44Breech presentation (HP:0001623)2.38424686
45Femoral bowing (HP:0002980)2.37076842
46Abnormality of skeletal muscle fiber size (HP:0012084)2.36106741
47Epiphyseal dysplasia (HP:0002656)2.34156725
48Natal tooth (HP:0000695)2.33567791
49Vascular tortuosity (HP:0004948)2.33007015
50Mildly elevated creatine phosphokinase (HP:0008180)2.32386168
51Hypoplastic ischia (HP:0003175)2.31480400
52Dilatation of the ascending aorta (HP:0005111)2.29512503
53Degeneration of the lateral corticospinal tracts (HP:0002314)2.28192720
54Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.28192720
55Joint laxity (HP:0001388)2.26451116
56Disproportionate tall stature (HP:0001519)2.25837088
57Elbow flexion contracture (HP:0002987)2.24560603
58Aortic aneurysm (HP:0004942)2.24118621
59Buphthalmos (HP:0000557)2.22933130
60Aortic valve stenosis (HP:0001650)2.22915010
61Mitral regurgitation (HP:0001653)2.22879574
62Round ear (HP:0100830)2.22737548
63Cerebral aneurysm (HP:0004944)2.21760333
64Stridor (HP:0010307)2.21391158
65Delayed cranial suture closure (HP:0000270)2.21219889
66Thin bony cortex (HP:0002753)2.20528133
67Cupped ribs (HP:0000887)2.20360444
68Overgrowth (HP:0001548)2.19746208
69Generalized amyotrophy (HP:0003700)2.18365056
70Arterial tortuosity (HP:0005116)2.17363535
71Neurofibrillary tangles (HP:0002185)2.16749259
72Premature skin wrinkling (HP:0100678)2.15454274
73Abnormality of the acetabulum (HP:0003170)2.14929595
74Nuclear cataract (HP:0100018)2.12627149
75Flared iliac wings (HP:0002869)2.11496624
76Ulnar bowing (HP:0003031)2.08719110
77Wrist flexion contracture (HP:0001239)2.08658845
78Platyspondyly (HP:0000926)2.08527198
79Distal upper limb amyotrophy (HP:0007149)2.06389522
80Upper limb amyotrophy (HP:0009129)2.06389522
81Long toe (HP:0010511)2.05541833
82Abnormality of the phalanges of the 2nd finger (HP:0009541)2.04198644
83Abnormality of the ischium (HP:0003174)1.98496977
84Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.97571058
85Urinary glycosaminoglycan excretion (HP:0003541)1.95145443
86Mucopolysacchariduria (HP:0008155)1.95145443
87Deviation of the hallux (HP:0010051)1.93720074
88Nonimmune hydrops fetalis (HP:0001790)1.93682094
89Delayed closure of the anterior fontanelle (HP:0001476)1.93563553
90Coxa vara (HP:0002812)1.93191318
91Osteolytic defects of the phalanges of the hand (HP:0009771)1.92197800
92Osteolytic defects of the hand bones (HP:0009699)1.92197800
93Hallux valgus (HP:0001822)1.91645585
94Camptodactyly of toe (HP:0001836)1.90948828
95Keratoconus (HP:0000563)1.89833076
96Increased corneal curvature (HP:0100692)1.89833076
97Ovoid vertebral bodies (HP:0003300)1.89564935
98Abnormality of mucopolysaccharide metabolism (HP:0011020)1.89546332
99Abnormality of polysaccharide metabolism (HP:0011012)1.89546332
100Abnormality of glycosaminoglycan metabolism (HP:0004371)1.89546332
101Turricephaly (HP:0000262)1.87955135
102Congenital glaucoma (HP:0001087)1.86357916
103Venous abnormality (HP:0002624)1.83742094
104Ectopia lentis (HP:0001083)1.83686279
105Hypophosphatemic rickets (HP:0004912)1.82800442
106Tibial bowing (HP:0002982)1.82639719
107Hyperacusis (HP:0010780)1.82553991
108Achilles tendon contracture (HP:0001771)1.81974116
109Aplasia involving bones of the upper limbs (HP:0009823)1.81812600
110Aplasia of the phalanges of the hand (HP:0009802)1.81812600
111Aplasia involving bones of the extremities (HP:0009825)1.81812600
112Emphysema (HP:0002097)1.81763038
113Bowed forearm bones (HP:0003956)1.81205412
114Bowing of the arm (HP:0006488)1.81205412
115Hypoplasia of the iris (HP:0007676)1.80645898
116Obstructive sleep apnea (HP:0002870)1.80598711
117Inguinal hernia (HP:0000023)1.80480800
118Protruding ear (HP:0000411)1.79012776
119Vascular calcification (HP:0004934)1.78930941
120Venous insufficiency (HP:0005293)1.78663651
121Increased connective tissue (HP:0009025)1.78221681
122Hypoventilation (HP:0002791)1.78215163
123Thin skin (HP:0000963)1.78127099
124Abnormal umbilical cord blood vessels (HP:0011403)1.77894380
125Single umbilical artery (HP:0001195)1.77894380
126Abnormality of the fetal cardiovascular system (HP:0010948)1.77894380
127Hip contracture (HP:0003273)1.77812390
128Limb-girdle muscle weakness (HP:0003325)1.77369656
129Abnormality of the 2nd finger (HP:0004100)1.76952896
130Beaking of vertebral bodies (HP:0004568)1.75777013
131Spondylolisthesis (HP:0003302)1.75273932
132Broad face (HP:0000283)1.74784241
133Spinal cord compression (HP:0002176)1.74640600
134Flat cornea (HP:0007720)1.73729127
135Adrenal hypoplasia (HP:0000835)1.73556456
136Delayed epiphyseal ossification (HP:0002663)1.72474498
137Broad long bones (HP:0005622)1.71854587
138Absent frontal sinuses (HP:0002688)1.71282658
139Abnormality of skull ossification (HP:0002703)1.70564980
140Limited hip movement (HP:0008800)1.69585295
141Dysostosis multiplex (HP:0000943)1.69461112

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK394.42292318
2DDR24.14815299
3MYLK3.97587188
4TRIB33.56246381
5TLK13.31691108
6ERN13.28354245
7TESK12.85724733
8MET2.79160206
9EPHA32.72753742
10OXSR12.66205217
11EPHB12.60205277
12PRPF4B2.41316742
13PBK2.40031687
14MAPKAPK52.31843049
15RIPK12.08787538
16WNK42.03513817
17TGFBR21.95682133
18PKN11.94849569
19FGFR21.90907515
20TESK21.88326443
21DMPK1.80757854
22PAK41.78675376
23CDC42BPA1.76384637
24WNK11.76157407
25STK381.75684552
26ROCK21.72821980
27PDGFRA1.70554285
28CLK11.60748107
29EPHB21.55934042
30NME21.54043154
31LATS21.52818464
32EPHA21.52239399
33UHMK11.49155961
34IRAK11.48892016
35MST1R1.48102172
36PAK31.47031611
37CDK191.43522968
38LIMK11.41422183
39BCR1.39477391
40MOS1.35299341
41IRAK31.33564148
42CAMK2D1.32577444
43NTRK11.31339250
44SMG11.27020813
45PRKD21.17707357
46ICK1.12996019
47PKN21.12736715
48CAMK2B1.11161800
49CSNK1G11.09902778
50RPS6KA21.09091695
51PDGFRB1.08156096
52LMTK21.04924326
53PRKD11.02070014
54AKT31.01788630
55MTOR1.01278898
56DYRK21.01276963
57PAK20.98997472
58MAP2K30.98043393
59FGFR40.97620932
60TTN0.97499573
61ERBB40.97481680
62CSNK1A1L0.97350612
63CSNK1G30.96631064
64MAPK150.96544205
65MAPK70.96427041
66DAPK30.96333270
67EIF2AK10.94960447
68MAP3K30.94811698
69MAP3K60.93672183
70IRAK20.93138611
71RPS6KA50.92222912
72PRKCE0.90088562
73CASK0.88272004
74PNCK0.86190564
75HIPK20.83958159
76NME10.83902331
77FER0.83731435
78NLK0.83245248
79ARAF0.82423692
80PTK20.81568056
81BMX0.81527845
82ROCK10.81116332
83CDK140.80572763
84PLK20.79823884
85PRKG20.79240506
86TRPM70.78243990
87CAMK2G0.77713389
88TAOK20.76747455
89PAK10.75109078
90BMPR20.74103172
91GSK3A0.71507375
92SCYL20.71498713
93FLT30.71474935
94NEK90.71040309
95NEK60.70912488
96SIK10.70908506
97MKNK10.68242856
98KSR20.62681449
99MAP3K70.61355050
100ILK0.61043508
101RPS6KC10.60495190
102RPS6KL10.60495190
103ZAP700.60460881
104PTK60.60322632
105JAK10.60299293
106EEF2K0.59235886
107TBK10.58322029
108KIT0.56558072
109TYRO30.56232859
110MAP3K20.56206018
111CAMK2A0.55996599
112CDK120.55239702
113MAPKAPK30.55154502
114MARK20.54737567
115LATS10.54721568
116PIM20.54388291
117PAK60.52443717
118FGR0.51925732
119INSR0.51320038
120MAP2K10.50238283
121PIK3CA0.49777775
122PIK3CG0.48662066
123STK30.48619472
124CDK150.48493666
125PTK2B0.48335669
126BMPR1B0.48034346
127PRKD30.47600123
128MAP2K20.47163621
129PDPK10.44937314
130MAP3K10.44829975
131TNIK0.44645907
132INSRR0.44634513
133CDK11A0.43981944
134ABL20.42781518
135MAPKAPK20.42562278
136MELK0.42394674
137CSNK1G20.42218481
138NUAK10.41303021
139ADRBK10.40944941
140TYK20.40533257
141GRK70.40474391
142EIF2AK30.39887600
143CSK0.39881354
144RPS6KA60.38358120
145CDK180.37857301
146LRRK20.37531932
147CSNK1A10.37133864
148MAP3K80.36618688
149STK38L0.36233128
150MAPK110.36132334
151RET0.35186078
152DYRK1B0.33133551
153CAMK1G0.32768488
154CDK80.31586190
155FGFR10.31385952
156MKNK20.31143961
157PRKCQ0.30883212

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030604.49784427
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009004.02413817
3ECM-receptor interaction_Homo sapiens_hsa045123.63222572
4Steroid biosynthesis_Homo sapiens_hsa001003.06753426
5Glycosaminoglycan degradation_Homo sapiens_hsa005312.92512986
6Protein digestion and absorption_Homo sapiens_hsa049742.33431034
7Sphingolipid metabolism_Homo sapiens_hsa006002.22194268
8Fatty acid elongation_Homo sapiens_hsa000622.20965525
9Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.99398395
10Axon guidance_Homo sapiens_hsa043601.94318818
11Focal adhesion_Homo sapiens_hsa045101.91111394
12Ether lipid metabolism_Homo sapiens_hsa005651.89976877
13Vibrio cholerae infection_Homo sapiens_hsa051101.87272575
14Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.67426644
15Hedgehog signaling pathway_Homo sapiens_hsa043401.64484835
16Renal cell carcinoma_Homo sapiens_hsa052111.61698706
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.57811002
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.55822998
19Small cell lung cancer_Homo sapiens_hsa052221.50375256
20PI3K-Akt signaling pathway_Homo sapiens_hsa041511.50374280
21Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.49015484
22Oxidative phosphorylation_Homo sapiens_hsa001901.41443929
23Malaria_Homo sapiens_hsa051441.39467249
24Sulfur metabolism_Homo sapiens_hsa009201.36380177
25Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.31509457
26Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.30305428
27Prion diseases_Homo sapiens_hsa050201.22943946
28Central carbon metabolism in cancer_Homo sapiens_hsa052301.22455681
29Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.20413514
30Dilated cardiomyopathy_Homo sapiens_hsa054141.20063884
31TGF-beta signaling pathway_Homo sapiens_hsa043501.17564759
32Basal cell carcinoma_Homo sapiens_hsa052171.17402531
33Bladder cancer_Homo sapiens_hsa052191.16065399
34Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.14367171
35Proteoglycans in cancer_Homo sapiens_hsa052051.14093111
36Adherens junction_Homo sapiens_hsa045201.13754088
37Prostate cancer_Homo sapiens_hsa052151.13584992
38Thyroid hormone synthesis_Homo sapiens_hsa049181.10089033
39Folate biosynthesis_Homo sapiens_hsa007901.08652154
40Lysosome_Homo sapiens_hsa041421.07293538
41Chronic myeloid leukemia_Homo sapiens_hsa052201.07010731
42Alzheimers disease_Homo sapiens_hsa050101.03969902
43Wnt signaling pathway_Homo sapiens_hsa043101.02408853
44Galactose metabolism_Homo sapiens_hsa000521.02238915
45Other glycan degradation_Homo sapiens_hsa005111.00721528
46Serotonergic synapse_Homo sapiens_hsa047260.99604936
47Phagosome_Homo sapiens_hsa041450.98883533
48AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.96491221
49Cocaine addiction_Homo sapiens_hsa050300.94213986
50Amoebiasis_Homo sapiens_hsa051460.93888166
51Long-term depression_Homo sapiens_hsa047300.93639956
52mTOR signaling pathway_Homo sapiens_hsa041500.93303054
53Hippo signaling pathway_Homo sapiens_hsa043900.92400932
54Vascular smooth muscle contraction_Homo sapiens_hsa042700.91997276
55Rheumatoid arthritis_Homo sapiens_hsa053230.91679339
56Tight junction_Homo sapiens_hsa045300.90149892
57Melanoma_Homo sapiens_hsa052180.89865709
58Ras signaling pathway_Homo sapiens_hsa040140.89459342
59Maturity onset diabetes of the young_Homo sapiens_hsa049500.88662854
60Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.86482879
61Regulation of actin cytoskeleton_Homo sapiens_hsa048100.85832510
62Shigellosis_Homo sapiens_hsa051310.84956766
63Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.84167045
64Phospholipase D signaling pathway_Homo sapiens_hsa040720.83484757
65Sphingolipid signaling pathway_Homo sapiens_hsa040710.82412722
66Gap junction_Homo sapiens_hsa045400.79753736
67Notch signaling pathway_Homo sapiens_hsa043300.79321759
68Cardiac muscle contraction_Homo sapiens_hsa042600.79213712
69Parkinsons disease_Homo sapiens_hsa050120.78767168
70Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.74088823
71MicroRNAs in cancer_Homo sapiens_hsa052060.73876258
72Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.73783268
73Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.73534798
74Complement and coagulation cascades_Homo sapiens_hsa046100.72846909
75Arachidonic acid metabolism_Homo sapiens_hsa005900.72628644
76Neurotrophin signaling pathway_Homo sapiens_hsa047220.71903416
77Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.69526008
78Melanogenesis_Homo sapiens_hsa049160.69165199
79Thyroid hormone signaling pathway_Homo sapiens_hsa049190.68695043
80Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.66656723
81Linoleic acid metabolism_Homo sapiens_hsa005910.66459941
82Endocytosis_Homo sapiens_hsa041440.65712704
83Pertussis_Homo sapiens_hsa051330.63658699
84Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.63368234
85Longevity regulating pathway - mammal_Homo sapiens_hsa042110.63258287
86GABAergic synapse_Homo sapiens_hsa047270.62962125
87RNA polymerase_Homo sapiens_hsa030200.62606355
88Cholinergic synapse_Homo sapiens_hsa047250.61557436
89N-Glycan biosynthesis_Homo sapiens_hsa005100.61381307
90TNF signaling pathway_Homo sapiens_hsa046680.61348119
91Ovarian steroidogenesis_Homo sapiens_hsa049130.60980653
92Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.59792212
93Collecting duct acid secretion_Homo sapiens_hsa049660.59384781
94Hepatitis C_Homo sapiens_hsa051600.58320034
95VEGF signaling pathway_Homo sapiens_hsa043700.57682676
96Toxoplasmosis_Homo sapiens_hsa051450.57335961
97Fructose and mannose metabolism_Homo sapiens_hsa000510.55794913
98Ribosome_Homo sapiens_hsa030100.55753221
99Aldosterone synthesis and secretion_Homo sapiens_hsa049250.55729821
100Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.55084329
101Pathways in cancer_Homo sapiens_hsa052000.54837415
102Pentose phosphate pathway_Homo sapiens_hsa000300.52536317
103Glioma_Homo sapiens_hsa052140.52453947
104Endometrial cancer_Homo sapiens_hsa052130.51433798
105Insulin resistance_Homo sapiens_hsa049310.51415639
106Renin secretion_Homo sapiens_hsa049240.50419053
107Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.50305789
108Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.49992360
109Prolactin signaling pathway_Homo sapiens_hsa049170.48853725
110Platelet activation_Homo sapiens_hsa046110.47406407
111ErbB signaling pathway_Homo sapiens_hsa040120.47294430
112AMPK signaling pathway_Homo sapiens_hsa041520.47201320
113Insulin signaling pathway_Homo sapiens_hsa049100.45963540
114alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.44955998
115Morphine addiction_Homo sapiens_hsa050320.44212776
116Rap1 signaling pathway_Homo sapiens_hsa040150.44073396
117Thyroid cancer_Homo sapiens_hsa052160.43489027
118Arginine and proline metabolism_Homo sapiens_hsa003300.43273016
119HTLV-I infection_Homo sapiens_hsa051660.43211783
120Salmonella infection_Homo sapiens_hsa051320.42912333
121Inositol phosphate metabolism_Homo sapiens_hsa005620.42699862
122Choline metabolism in cancer_Homo sapiens_hsa052310.41763759
123Hepatitis B_Homo sapiens_hsa051610.41701737
124Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.41208736
125Dopaminergic synapse_Homo sapiens_hsa047280.41205025
126Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.40933170
127Estrogen signaling pathway_Homo sapiens_hsa049150.40724163
128Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.40248981
129Circadian entrainment_Homo sapiens_hsa047130.39978175
130Leukocyte transendothelial migration_Homo sapiens_hsa046700.39413696
131Pancreatic cancer_Homo sapiens_hsa052120.38975827
132SNARE interactions in vesicular transport_Homo sapiens_hsa041300.38808729
133cGMP-PKG signaling pathway_Homo sapiens_hsa040220.38735264
134GnRH signaling pathway_Homo sapiens_hsa049120.37380695
135Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.36801299
136Alcoholism_Homo sapiens_hsa050340.36713060
137Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.36043087
138Insulin secretion_Homo sapiens_hsa049110.35262291
139MAPK signaling pathway_Homo sapiens_hsa040100.35069289
140Huntingtons disease_Homo sapiens_hsa050160.34831001

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